Genomes and Genes
Summary: The influence of study results on the chances of publication and the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Publication bias has an impact on the interpretation of clinical trials and meta-analyses. Bias can be minimized by insistence by editors on high-quality research, thorough literature reviews, acknowledgement of conflicts of interest, modification of peer review practices, etc.
Publications265 found, 100 shown here
- Selective publication of antidepressant trials and its influence on apparent efficacyErick H Turner
Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA
N Engl J Med 358:252-60. 2008..Selective publication of clinical trials--and the outcomes within those trials--can lead to unrealistic estimates of drug effectiveness and alter the apparent risk-benefit ratio...
- Comparison of two methods to detect publication bias in meta-analysisJaime L Peters
Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester, England
JAMA 295:676-80. 2006Egger's regression test is often used to help detect publication bias in meta-analyses...
- Systematic review of the empirical evidence of study publication bias and outcome reporting biasKerry Dwan
Centre for Medical Statistics and Health Evaluation, University of Liverpool, Liverpool, United Kingdom
PLoS ONE 3:e3081. 2008..Study publication bias has been recognised as a potential threat to the validity of meta-analysis and can make the readily available ..
- The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessedJonathan J Deeks
Screening and Test Evaluation Program, School of Public Health, University of Sydney, Sydney, New South Wales 2006, Australia
J Clin Epidemiol 58:882-93. 2005b>Publication bias and other sample size effects are issues for meta-analyses of test accuracy, as for randomized trials...
- A modified test for small-study effects in meta-analyses of controlled trials with binary endpointsRoger M Harbord
MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK
Stat Med 25:3443-57. 2006b>Publication bias and related bias in meta-analysis is often examined by visually checking for asymmetry in funnel plots of treatment effect against its standard error...
- Effects of common polymorphisms rs11614913 in miR-196a2 and rs2910164 in miR-146a on cancer susceptibility: a meta-analysisWei Xu
Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
PLoS ONE 6:e20471. 2011..Rs11614913 in miR-196a2 and rs2910164 in miR-146a are shown to associate with increased/decreased cancer risk. We performed a meta-analysis to systematically summarize the possible association...
- Publication bias in reports of animal stroke studies leads to major overstatement of efficacyEmily S Sena
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom
PLoS Biol 8:e1000344. 2010..The existence and any impact of such "publication bias" in the laboratory sciences have not been described...
- A comparison of methods to detect publication bias in meta-analysisP Macaskill
Department of Public Health and Community Medicine, University of Sydney, NSW, Australia 2006
Stat Med 20:641-54. 2001Meta-analyses are subject to bias for many of reasons, including publication bias. Asymmetry in a funnel plot of study size against treatment effect is often used to identify such bias...
- GRADE guidelines: 5. Rating the quality of evidence--publication biasGordon H Guyatt
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
J Clin Epidemiol 64:1277-82. 2011..as low-quality evidence, but both can be rated down if a body of evidence is associated with a high risk of publication bias. Even when individual studies included in best-evidence summaries have a low risk of bias, publication bias ..
- Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and selective serotonin reuptake inhibitor controlled trialsDirk Eyding
German Cancer Society, Berlin, Germany
BMJ 341:c4737. 2010To assess the benefits and harms of reboxetine versus placebo or selective serotonin reuptake inhibitors (SSRIs) in the acute treatment of depression, and to measure the impact of potential publication bias in trials of reboxetine.
- Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiologyJohn Attia
Centre for Clinical Epidemiology and Biostatistics, Faculty of Health, University of Newcastle, Royal Newcastle Hospital, David Maddison Building, Newcastle NSW 2300, Australia
J Clin Epidemiol 56:297-303. 2003..Heterogeneity was assessed in 28 (76%), but only 7 of 37 (19%) studies checked for publication bias. Nine (24%) studies assessed the goodness-of-fit of Hardy-Weinberg equilibrium, and eight (22%) gave any ..
- Evidence b(i)ased medicine--selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applicationsHans Melander
Medical Products Agency, Box 23, S 751 03 Uppsala, Sweden
BMJ 326:1171-3. 2003To investigate the relative impact on publication bias caused by multiple publication, selective publication, and selective reporting in studies sponsored by pharmaceutical companies.
- Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database surveyIkhlaaq Ahmed
MRC Midlands Hub for Trials Methodology Research, School of Health and Population Sciences, University of Birmingham, Birmingham B15 2TT, UK
BMJ 344:d7762. 2012To examine the potential for publication bias, data availability bias, and reviewer selection bias in recently published meta-analyses that use individual participant data and to investigate whether authors of such meta-analyses seemed ..
- Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetryJaime L Peters
Department of Health Sciences, University of Leicester, Leicester, UK
J Clin Epidemiol 61:991-6. 2008To present the contour-enhanced funnel plot as an aid to differentiating asymmetry due to publication bias from that due to other factors.
- Outcome reporting among drug trials registered in ClinicalTrials.govFlorence T Bourgeois
Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Ann Intern Med 153:158-66. 2010..Clinical trial registries are in widespread use to promote transparency around trials and their results...
- Direction and impact of language bias in meta-analyses of controlled trials: empirical studyPeter Juni
Medical Research Council Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK
Int J Epidemiol 31:115-23. 2002..We examined the influence of trials published in languages other than English on combined estimates and conclusions of published meta-analyses...
- The association between common genetic variant of microRNA-146a and cancer susceptibilityLi Xin Qiu
Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
Cytokine 56:695-8. 2011..Despite some limitations, this meta-analysis suggests that the miR-146a G allele is a low-penetrant risk factor for papillary thyroid carcinoma development...
- The appropriateness of asymmetry tests for publication bias in meta-analyses: a large surveyJohn P A Ioannidis
Tufts University School of Medicine, Boston, Mass, USA
CMAJ 176:1091-6. 2007..Inappropriate application can generate misleading inferences about publication bias. We aimed to measure, in a survey of meta-analyses, how frequently the application of these tests would be ..
- Pooling of animal experimental data reveals influence of study design and publication biasMalcolm R Macleod
National Stroke Research Institute, Melbourne, Australia
Stroke 35:1203-8. 2004..To our knowledge, such assessments have not been made. Nicotinamide is a candidate neuroprotective drug with efficacy in experimental stroke, but the limits to and characteristics of that efficacy have not been fully described...
- How can we improve the pre-clinical development of drugs for stroke?Emily Sena
Department of Clinical Neurosciences, University of Edinburgh, UK
Trends Neurosci 30:433-9. 2007..We believe the adoption of these standards will lead to improved effectiveness and efficiency in the selection of drugs for clinical trials in stroke and in the design of those trials...
- Comparison of registered and published primary outcomes in randomized controlled trialsSylvain Mathieu
INSERM, U738, Assistance Publique des Hopitaux de Paris, Hopital Bichat Claude Bernard, Département d Epidémiologie Biostatistique et Recherche Clinique, Paris, France
JAMA 302:977-84. 2009..As of 2005, the International Committee of Medical Journal Editors required investigators to register their trials prior to participant enrollment as a precondition for publishing the trial's findings in member journals...
- Systematic review of the empirical evidence of study publication bias and outcome reporting bias - an updated reviewKerry Dwan
Department of Biostatistics, University of Liverpool, Liverpool, England
PLoS ONE 8:e66844. 2013..Study publication bias and outcome reporting bias have been recognised as a potential threat to the validity of meta-analysis and ..
- Preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement and publication biasKarsten Knobloch
Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Germany
J Craniomaxillofac Surg 39:91-2. 2011b>Publication bias is a major problem in evidence based medicine...
- Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentationKristin Rising
School of Medicine, University of California San Francisco, San Francisco, California, USA
PLoS Med 5:e217; discussion e217. 2008....
- Selective reporting biases in cancer prognostic factor studiesPanayiotis A Kyzas
Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece
J Natl Cancer Inst 97:1043-55. 2005..We probed these biases in a meta-analysis of a prognostic factor for head and neck squamous cell cancer (HNSCC) mortality that has drawn wide attention--the status of the tumor suppressor protein TP53...
- Fate of biomedical research protocols and publication bias in France: retrospective cohort studyEvelyne Decullier
Clinical Research Unit, DIM des Hospices Civils de Lyon, 162 Avenue Lacassagne, 69424 Lyon Cedex 03, France
BMJ 331:19. 2005To describe the fate of protocols approved by the French research ethics committees, a national system created by the French 1988 Huriet-Sérusclat Act; to assess publication bias at a national level.
- Has-miR-146a polymorphism (rs2910164) and cancer risk: a meta-analysis of 19 case-control studiesJun Wang
Department of Oncology, General Hospital, Jinan Command of the People s Liberation Army, Shifan Street 25, Tianqiao District, Jinan, 250031, China
Mol Biol Rep 39:4571-9. 2012..However, further well-designed studies with large sample size will be necessary to validate the risk identified in the current meta-analysis...
- "Hardly worth the effort"? Medical journals' policies and their editors' and publishers' views on trial registration and publication bias: quantitative and qualitative studyElizabeth Wager
Sideview, Princes Risborough, Bucks HP27 9DE, UK
BMJ 347:f5248. 2013To determine the proportion of medical journals requiring trial registration and to understand their reasons for adopting (or not adopting) such policies and other measures designed to reduce publication bias.
- Arcsine test for publication bias in meta-analyses with binary outcomesGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Centre, Freiburg, Germany
Stat Med 27:746-63. 2008..One possible reason for such 'small study effects' is publication bias. This is said to occur when the chance of a smaller study being published is increased if it shows a stronger ..
- Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration databaseErick H Turner
Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
PLoS Med 9:e1001189. 2012b>Publication bias compromises the validity of evidence-based medicine, yet a growing body of research shows that this problem is widespread. Efficacy data from drug regulatory agencies, e.g...
- Outcome reporting in industry-sponsored trials of gabapentin for off-label useS Swaroop Vedula
Center for Clinical Trials, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
N Engl J Med 361:1963-71. 2009..There is good evidence of selective outcome reporting in published reports of randomized trials...
- Impact of reporting bias in network meta-analysis of antidepressant placebo-controlled trialsLudovic Trinquart
French Cochrane Centre, Paris, France
PLoS ONE 7:e35219. 2012..Indirect comparisons of competing treatments by network meta-analysis (NMA) are increasingly in use. Reporting bias has received little attention in this context. We aimed to assess the impact of such bias in NMAs...
- Factors associated with findings of published trials of drug-drug comparisons: why some statins appear more efficacious than othersLisa Bero
Clinical Pharmacy and Health Policy, University of California, San Francisco, California, United States of America
PLoS Med 4:e184. 2007....
- Reporting bias in medical research - a narrative reviewNatalie McGauran
Institute for Quality and Efficiency in Health Care, Dillenburger Str 27, 51105 Cologne, Germany
Trials 11:37. 2010..aim of this narrative review is to gain an overview of reporting bias in the medical literature, focussing on publication bias and selective outcome reporting...
- Performance of the trim and fill method in the presence of publication bias and between-study heterogeneityJaime L Peters
Department of Health Sciences, University of Leicester, Leicester LE1 7RH, U K
Stat Med 26:4544-62. 2007The trim and fill method allows estimation of an adjusted meta-analysis estimate in the presence of publication bias. To date, the performance of the trim and fill method has had little assessment...
- Assessing publication bias in genetic association studies: evidence from a recent meta-analysisMarcus R Munafo
Department of Clinical Pharmacology, Cancer Research UK, General Practice Research Group, University of Oxford, Oxford OX2 6HE, UK
Psychiatry Res 129:39-44. 2004b>Publication bias may exist when nonsignificant findings remain unpublished, thereby artificially inflating the apparent magnitude of an effect...
- Too good to be true: publication bias in two prominent studies from experimental psychologyGregory Francis
Department of Psychological Sciences, Purdue University, West Lafayette, IN, USA
Psychon Bull Rev 19:151-6. 2012..the final arbiter of phenomena in science, but replication is undermined when there is evidence for publication bias. Evidence for publication bias in a set of experiments can be found when the observed number of rejections of ..
- Impact of funding on biomedical research: a retrospective cohort studyEvelyne Decullier
Clinical Epidemiology Unit DIM Hospices Civils de Lyon, Lyon, France
BMC Public Health 6:165. 2006....
- Journal prestige, publication bias, and other characteristics associated with citation of published studies in peer-reviewed journalsMichael Callaham
Division of Emergency Medicine, University of California, San Francisco, CA 94143 0208, USA
JAMA 287:2847-50. 2002..Citation by other authors is important in the dissemination of published science, but factors predicting it are little studied...
- miR-196a2 C allele is a low-penetrant risk factor for cancer developmentLi Xin Qiu
Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
Cytokine 56:589-92. 2011..TT: OR=1.19, 95% CI=1.06-1.35; dominant model: OR=1.13, 95% CI=1.01-1.25). Despite some limitations, this meta-analysis suggests that the miR-196a2 C allele is a low-penetrant risk factor for cancer development...
- Associations between asymmetry and human attractiveness: Possible direct effects of asymmetry and signatures of publication biasStefan Van Dongen
Group of Evolutionary Ecology, University of Antwerp, Groenenborgerlaan 171, B 2020, Antwerp, Belgium
Ann Hum Biol 38:317-23. 2011..The evolutionary importance of these associations, however, critically depends on the role of DI in driving these correlations. A direct effect of FA reduces the role of DI...
- Publication bias and time-trend bias in meta-analysis of bicycle helmet efficacy: a re-analysis of Attewell, Glase and McFadden, 2001Rune Elvik
Institute of Transport Economics, Gaustadalleen 21, NO 0349 Oslo, Norway
Accid Anal Prev 43:1245-51. 2011..reported by Attewell, Glase, and McFadden (Accident Analysis and Prevention 2001, 345-352) was influenced by publication bias and time-trend bias that was not controlled for...
- Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: a meta-analysisZhongxia Wang
Department of Hepatobiliary Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, China
PLoS ONE 7:e40039. 2012..However, published results are inconsistent and inconclusive. In the present study, we performed a meta-analysis to systematically summarize the possible association between the two SNPs and the risk for HCC...
- Asymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracyFujian Song
Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, UK
Int J Epidemiol 31:88-95. 2002Despite the great possibility of publication bias in studies of diagnostic test research, empirical studies about publication bias have mainly focused on studies of treatment effect.
- Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studiesFujian Song
School of Medicine, Health Policy and Practice, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK
BMC Med Res Methodol 9:79. 2009..We conducted a meta-analysis to ascertain the strength and consistency of the association between study results and formal publication...
- Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: an exploratory analysis of head-to-head comparison studies of second-generation antipsychoticsStephan Heres
Klinik und Poliklinik für Psychiatrie und Psychotherapie der Technischen Universität München am Klinikum rechts der Isar, Moehlstrasse 26, 81675 Munich, Germany
Am J Psychiatry 163:185-94. 2006....
- Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articlesAn Wen Chan
Centre for Statistics in Medicine, Institute of Health Sciences, Headington, Oxford, England
JAMA 291:2457-65. 2004..Selective reporting of outcomes within published studies based on the nature or direction of their results has been widely suspected, but direct evidence of such bias is currently limited to case reports...
- Obstacles and opportunities in meta-analysis of genetic association studiesGeorgia Salanti
MRC Biostatistics Unit, Cambridge, UK
Genet Med 7:13-20. 2005..We believe that systematic review and meta-analysis has an important role to play in understanding genetic association studies and should help us to separate the wheat from the chaff...
- Assessment of regression-based methods to adjust for publication bias through a comprehensive simulation studySantiago G Moreno
Department of Health Sciences, University of Leicester, Leicester, UK
BMC Med Res Methodol 9:2. 2009..This issue potentially mean inappropriate conclusions are drawn from a meta-analysis. If meta-analysis is to be used to inform decision-making, a reliable way to adjust pooled estimates for potential funnel plot asymmetry is required...
- Increased risk of breast cancer associated with CC genotype of Has-miR-146a Rs2910164 polymorphism in EuropeansHai Lian
Department of Pathology, The Eleventh Institute of Academy of Military Medical Sciences, Changchun, China
PLoS ONE 7:e31615. 2012..However, the results remain conflicting rather than conclusive...
- Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery diseaseHarry Hemingway
Department of Epidemiology and Public Health, University College London, United Kingdom
PLoS Med 7:e1000286. 2010..We sought to evaluate the quality of prognostic research evidence for the association of C-reactive protein (CRP) with fatal and nonfatal events among patients with stable coronary disease...
- Systematic evaluation and comparison of statistical tests for publication biasYasuaki Hayashino
Department of Epidemiology and Healthcare Research, Kyoto University Graduate School of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto, Japan
J Epidemiol 15:235-43. 2005This study evaluates the statistical and discriminatory powers of three statistical test methods (Begg's, Egger's, and Macaskill's) to detect publication bias in meta-analyses.
- Capture-recapture is a potentially useful method for assessing publication biasDerrick A Bennett
The Clinical Trials Research Unit, 3 Ferncroft Street, Grafton, Faculty of Medicine and Health Sciences, Private Bag 92019, University of Auckland, New Zealand
J Clin Epidemiol 57:349-57. 2004b>Publication bias is a problem in systematic reviews of randomized controlled trials...
- What are the implications of optimism bias in clinical research?Iain Chalmers
James Lind Library, Summertown Pavilion, Oxford OX2 7LG, UK
Lancet 367:449-50. 2006
- Publication bias, with a focus on psychiatry: causes and solutionsErick H Turner
Behavioral Health and Neurosciences Division, Portland Veterans Affairs Medical Center, P3MHDC, 3710 SW US Veterans Hospital Rd, Portland, OR 97239, USA
CNS Drugs 27:457-68. 2013b>Publication bias undermines the integrity of the evidence base by inflating apparent drug efficacy and minimizing drug harms, thus skewing the risk-benefit ratio...
- Publication bias in psychological science: prevalence, methods for identifying and controlling, and implications for the use of meta-analysesChristopher J Ferguson
Department of Psychology, Texas A and M International University, 5201 University Blvd, Laredo, TX 78041, USA
Psychol Methods 17:120-8. 2012The issue of publication bias in psychological science is one that has remained difficult to address despite decades of discussion and debate...
- Systematic reviews and meta-analyses of preclinical studies: publication bias in laboratory animal experimentsD A Korevaar
Department of General Practice, Academic Medical Center AMC, University of Amsterdam UvA, PO Box 22700, 1100 DD Amsterdam, The Netherlands
Lab Anim 45:225-30. 2011..They found 46 LAE meta-analyses (MAs), often of poor quality. Six of these 46 MAs tried to assess publication bias. Publication bias is the phenomenon of an experiment's results determining its likelihood of publication, ..
- Searching for unpublished trials in Cochrane reviews may not be worth the effortMieke L Van Driel
Department of General Practice and Primary Health Care, Ghent University, Belgium
J Clin Epidemiol 62:838-844.e3. 2009..To assess the value of searching for unpublished data by exploring the extent to which Cochrane reviews include unpublished data and by evaluating the quality of unpublished trials...
- Inflation of type I error rate in two statistical tests for the detection of publication bias in meta-analyses with binary outcomesGuido Schwarzer
Freiburg Center for Data Analysis and Modelling, University of Freiburg, Germany
Stat Med 21:2465-77. 2002..The validity of a meta-analysis may be affected by various sources of bias (for example, publication bias, language bias). Therefore, an analysis of bias should be an integral part of any systematic review...
- Publication bias and the failure of replication in experimental psychologyGregory Francis
Department of Psychological Sciences, Purdue University, 703 Third Street, West Lafayette, IN 47906, USA
Psychon Bull Rev 19:975-91. 2012..Rather than strengthen confidence in an effect, too much successful replication actually indicates publication bias, which invalidates entire sets of experimental findings...
- Effects of fish oil supplementation on inflammatory markers in chronic heart failure: a meta-analysis of randomized controlled trialsWei Xin
First Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, Peoples Republic of China
BMC Cardiovasc Disord 12:77. 2012..In this meta-analysis, we aimed to evaluate the influence of fish oil supplementation on circulating levels of inflammatory markers in patients with chronic heart failure...
- A meta-analysis of tumor necrosis factor-alpha, interleukin-6, and interleukin-10 in preeclampsiaCui Xie
Central Laboratory and Center of Prenatal Diagnosis, Shenzhen Baoan Maternal and Child Health Hospital, Shenzhen, People s Republic of China
Cytokine 56:550-9. 2011..Our findings strengthen the clinical evidence that PE is accompanied by exaggerated inflammatory responses, but do not support TNF-α-308G/A, IL-6-174G/C, and IL-10-1082A/G as candidate susceptibility loci in PE...
- Detecting and adjusting for small-study effects in meta-analysisGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center, Stefan Meier Strasse 26, D 79104 Freiburg, Germany
Biom J 53:351-68. 2011b>Publication bias and related types of small-study effects threaten the validity of systematic reviews. The existence of small-study effects has been demonstrated in empirical studies...
- MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysisErjiang Zhao
Department of Epidemiology and Biostatistics, Public Health School of Zhengzhou University, Zhengzhou, 450001, China
Mol Biol Rep 39:3471-7. 2012..TT (OR = 1.26, 95% CI = 0.84-1.87). Our meta-analysis suggests that MDM2 SNP309 polymorphism may increase the risk to breast cancer in Asian and African population...
- The Arg194Trp polymorphism in the XRCC1 gene and cancer risk in Chinese Mainland population: a meta-analysisJin Huang
West China Hospital West China Medical School, Sichuan University, Chengdu, Sichuan, China
Mol Biol Rep 38:4565-73. 2011..More intensive and deeper studies are needed to further reveal the mechanism between Arg194Trp polymorphisms of XRCC1 gene and cancer risks in Chinese Mainland population...
- X-ray repair cross-complementing group 1 polymorphisms and hepatocellular carcinoma: a meta-analysisTian Xie
Department of Hepatic Surgery, National Hepatobiliary and Enteric Surgery Research Center, Ministry of Health, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 18:4207-14. 2012..To perform a systematic meta-analysis to investigate the association between X-ray repair cross-complementing group 1 (XRCC1) polymorphisms and hepatocellular carcinoma (HCC) risk...
- Protocol for a systematic review on the extent of non-publication of research studies and associated study characteristicsSusan Portalupi
German Cochrane Centre, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany
Syst Rev 2:2. 2013..that non-published studies often have different results than those that are published, a phenomenon known as publication bias. When results are not published, or are published selectively based on the direction or the strength of the ..
- Publication bias and outcome reporting bias: agomelatine as a case exampleRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 49:11-4. 2011b>Publication bias and outcome reporting bias contribute to distorted perceptions of drug efficacy and the underreporting of adverse events...
- Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese populationXiaowei Xu
Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou, People s Republic of China
Cerebrovasc Dis 26:48-62. 2008..The aim of this study was to confirm the nature and number of genes contributing to stroke risk and qualify the genetic risk of each susceptibility gene in the Han Chinese population...
- Excess significance bias in the literature on brain volume abnormalitiesJohn P A Ioannidis
Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology Hellas, Ioannina, Greece
Arch Gen Psychiatry 68:773-80. 2011..Many studies report volume abnormalities in diverse brain structures in patients with various mental health conditions...
- Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common diseaseKirk E Lohmueller
Whitehead Massachuetts Institute of Technology Center for Genome Research, Cambridge, Massachusetts 02139, USA
Nat Genet 33:177-82. 2003..This excess of replications could not be reasonably explained by publication bias and was concentrated among 11 of the 25 associations...
- Efficacy of cognitive-behavioural therapy and other psychological treatments for adult depression: meta-analytic study of publication biasPim Cuijpers
Department of Clinical Psychology, VU University Amsterdam, Van der Boechorststraat 1, Amsterdam, The Netherlands
Br J Psychiatry 196:173-8. 2010It is not clear whether the effects of cognitive-behavioural therapy and other psychotherapies have been overestimated because of publication bias.
- Do pressures to publish increase scientists' bias? An empirical support from US States DataDaniele Fanelli
INNOGEN and Institute for the Study of Science, Technology and Innovation, The University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e10271. 2010..The same phenomenon might be observed in other countries where academic competition and pressures to publish are high...
- Modelling publication bias in meta-analysis: a reviewA J Sutton
Department of Epidemiology and Public Health, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
Stat Methods Med Res 9:421-45. 2000Meta-analysis is now a widely used technique for summarizing evidence from multiple studies. Publication bias, the bias induced by the fact that research with statistically significant results is potentially more likely to be submitted ..
- Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed moodKatherine M Appleton
School of Psychology, Queen s University, Belfast, UK
Am J Clin Nutr 91:757-70. 2010..The debate over a role for n-3 long-chain polyunsaturated fatty acids (n-3 PUFAs) in depressed mood continues...
- Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication biasM R Munafò
Department of Experimental Psychology, University of Bristol, Bristol, UK
Mol Psychiatry 12:454-61. 2007..and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact ..
- Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug developmentJames F Fries
Stanford University School of Medicine, Palo Alto, California, USA
Arthritis Res Ther 6:R250-5. 2004..0001). Equipoise clearly was being systematically violated. Publication bias appeared to be an incomplete explanation for this dramatic result; this bias occurs after a study is ..
- Almost all articles on cancer prognostic markers report statistically significant resultsPanayiotis A Kyzas
Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
Eur J Cancer 43:2559-79. 2007..Under strong reporting bias, statistical significance loses its discriminating ability for the importance of prognostic markers...
- Delay and failure to publish dental researchJ M Scholey
Department of Clinical Dental Sciences, Liverpool University Dental Hospital and School of Dentistry, Pembroke Place, Liverpool L3 5PS
Evid Based Dent 6:58-61. 2005..To investigate the incidence and time taken to full publication of abstracts presented at dental scientific meetings...
- Cigarette smoking and p16INK4α gene promoter hypermethylation in non-small cell lung carcinoma patients: a meta-analysisBo Zhang
Department of Toxicology, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat Sen University, Guangzhou, China
PLoS ONE 6:e28882. 2011..Recently, many studies have investigated the association between cigarette smoking and p16(INK4α) gene hypermethylation in lung cancer, but could not reach a unanimous conclusion...
- The role of conflict of interest in reporting of scientific informationRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 136:253-9. 2009....
- A meta-analysis of CDH1 C-160A genetic polymorphism and gastric cancer riskYun Cui
Department of Gastroenterology, Renji Hospital, Shanghai Institute of Gastrointestinal Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, People s Republic of China
DNA Cell Biol 30:937-45. 2011..Genotyping techniques, sample size, quality appraisal scores, or article publication time did not constitute the source of heterogeneity across studies; and no publication biases were found in our meta-analysis...
- The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysisXin min Pan
Department of Forensic Pathology, College of Forensic Medicine, Henan University of Science and Technology, 31 Anhui Road, Jianxi District, Luoyang, Henan 471003, People s Republic of China
Mutagenesis 26:667-73. 2011..On the conservative standpoint, well-designed population-based studies with larger sample size in different ethnic groups should be performed to further confirm these results...
- Adjusting for publication biases across similar interventions performed well when compared with gold standard dataSantiago G Moreno
Department of Evaluation of Innovation and New Technologies, Fundació Clínic, C Urgell 216, baixos, Barcelona 08036, Spain
J Clin Epidemiol 64:1230-41. 2011..To extend, apply, and evaluate a regression-based approach to adjusting meta-analysis for publication and related biases. The approach uses related meta-analyses to improve estimation by borrowing strength on the degree of bias...
- Industry support and correlation to study outcome for papers published in SpineRahul V Shah
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA
Spine (Phila Pa 1976) 30:1099-104; discussion 1105. 2005..Retrospective review of articles published in the journal Spine...
- Modelling multiple sources of dissemination bias in meta-analysisJack Bowden
MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 0SR, U K
Stat Med 29:945-55. 2010..This may be caused by publication bias through the decisions of journal editors, by selective reporting of research results by authors or by a ..
- A case study of publication bias in an influential series of reviews of drug educationJim McCambridge
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Centre for Research on Drugs and Health Behaviour, London, UK
Drug Alcohol Rev 26:463-8. 2007There has been remarkably little demonstration of the deleterious impact of publication bias within addiction science or indeed in wider healthcare policy and practice...
- Reporting research results: a moral obligation for all researchersDavid Moher
Can J Anaesth 54:331-5. 2007
- More than numbers: the power of graphs in meta-analysisLeon Bax
Kitasato Clinical Research Center, Kitasato University, Sagamihara, Kanagawa, Japan
Am J Epidemiol 169:249-55. 2009..the assessment of graphs is widely used in an attempt to identify or rule out heterogeneity and publication bias. A variety of graphs are available for this purpose...
- Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication biasTiago V Pereira
Heart Institute InCor, Sao Paulo University Medical School, University of Sao Paulo, Brazil
J Hypertens 25:1763-74. 2007..To explore this hypothesis further, we performed a meta-analysis and re-evaluated the relationship between the three most widely studied NOS3 polymorphisms and hypertension status and blood pressure levels...
- Assessment of risk of bias among pediatric randomized controlled trialsMichael T Crocetti
Department of Pediatrics, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA
Pediatrics 126:298-305. 2010..The goal was to assess the risk of bias among pediatric, randomized, controlled trials (RCTs) reported in 8 high-impact journals...
- Dissemination and publication of research findings: an updated review of related biasesF Song
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
Health Technol Assess 14:iii, ix-xi, 1-193. 2010....
- -765G>C and 8473T>C polymorphisms of COX-2 and cancer risk: a meta-analysis based on 33 case-control studiesWei Zhu
Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Mol Biol Rep 37:277-88. 2010..In summary, this meta-analysis suggesting that -765G>C may cause an increased risk of colorectal carcinoma and esophageal cancer in Asian descents while 8473T>C polymorphism may cause a decreased risk of breast and lung cancer...
- Reporting the findings of clinical trials: a discussion paperD Ghersi
World Health Organization, Geneva, Switzerland
Bull World Health Organ 86:492-3. 2008
- N-acetylcysteine in the prevention of contrast-induced nephropathy: publication bias perpetuated by meta-analysesPaul T Vaitkus
Cardiology Division, M C 715, University of Illinois at Chicago, Chicago, IL 60612, USA
Am Heart J 153:275-80. 2007..We sought to examine the possibility of a publication bias and whether meta-analyses have magnified any potential publication bias.
- Publication bias in epidemiological studiesNazish Siddiqi
Department of Epidemiology, Michigan State University, East Lansing, Michigan, USA
Cent Eur J Public Health 19:118-20. 2011Communication of research findings is the utmost responsibility of all scientists. Publication bias occurs if scientific studies with negative or null results fail to get published...
- Effect of reporting bias on meta-analyses of drug trials: reanalysis of meta-analysesBETH HART
Department of Clinical Pharmacy, Institute for Health Policy Studies, University of California, San Francisco, 3333 California St, Suite 420, San Francisco, CA 94118, USA
BMJ 344:d7202. 2012..To investigate the effect of including unpublished trial outcome data obtained from the Food and Drug Administration (FDA) on the results of meta-analyses of drug trials...
- Time-lag bias in trials of pediatric antidepressants: a systematic review and meta-analysisMagdalena M Reyes
Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA
J Am Acad Child Adolesc Psychiatry 50:63-72. 2011..To determine whether there is evidence of a time-lag bias in the publication of pediatric antidepressant trials...
- Association between +61G polymorphism of the EGF gene and glioma risk in different ethnicities: a meta-analysisDianhui Tan
Department of Neurosurgery, First Affiliated Hospital of Shantou University Medical College, Shantou, PR China
Tohoku J Exp Med 222:229-35. 2010..14, 95%CI (1.02-1.27), P(heterogeneity) = 0.179, I² = 71.8]. In conclusion, EGF +61G allele represents a risk factor for glioma in European population and conversely a protective factor in Chinese population...
- Research funding, conflicts of interest, and the meta-methodology of public relationsSheldon Rampton
Center for Media and Democracy, Madison, WI 53703, USA
Public Health Rep 117:331-9. 2002
- Issues pertaining to data extraction and classification and publication bias in meta-analysis of the diagnostic accuracy of markers for bacterial infectionTroels Bygum Knudsen
Clin Infect Dis 40:1372-3; author reply 1373-4. 2005
- Exploring the Association Between Immune-Related Genetic Variation and HNSCCChaya Levovitz; Fiscal Year: 2013..include low statistical power in detecting modest risk sequence variants, false positive results, positive publication bias, and a moderate prior probability that each SNP individually confers substantial increase in risk14...
- Meta-Analysis of Interventions to Improve Medication AdherenceVicki S Conn; Fiscal Year: 2013..magnitude of effect, sample size weighted calculations, random-effects models, homogeneity (Q) assessment, publication bias analysis (I2), and to facilitate interpretation - Common Language Effect Size and conversion to original ..
- Breastfeeding RCT: Adolescent Neurocognitive and Respiratory FunctionEmily Oken; Fiscal Year: 2013..Existing evidence is largely based on observational studies, which are prone to measurement error, publication bias and reverse causality...
- Circulating Vitamin D Levels and Risk of Breast and Colorectal Cancer: a Pooled AStephanie A Smith-Warner; Fiscal Year: 2013..Further, new data will be generated in seven of the studies which will reduce the influence of publication bias. This proposal takes full advantage of extensive data collected throughout the world, builds upon the ..
- Quantifying Risk And Survival Benefit from Incompatible Kidney TransplantationBABAK JOHN ORANDI; Fiscal Year: 2013..is limited, as the UNOS national transplant registry does not collect data on incompatibilities, and inherent publication bias limits the current paradigm...
- Quantifying Risk And Survival Benefit from Incompatible Kidney TransplantationDorry Segev; Fiscal Year: 2013..in this field, future growth is currently limited by inferences from single-center reports which suffer from publication bias, lack of statistical power, inability to compare protocol effectiveness within a single-center (because of ..
- Treatment Success and Ethical Principle of EquipoiseBenjamin Djulbegovic; Fiscal Year: 2010..g. improving particular methodological deficiency, correcting for publication bias etc) resulting in the immediate practical application of our research...
- Comparative Effectiveness & Medical Interventions for Primary Open Angle GlaucomaKay Dickersin; Fiscal Year: 2010..We will validate the MTC meta-analysis models and assess the impact of publication bias. We will report and disseminate our findings on the comparative effectiveness of medical interventions for ..
- Equipoise and the research integrity of clinical trialsBenjamin Djulbegovic; Fiscal Year: 2003..However, we could not exclude publication bias as the explanation for the higher proportion of positive results in the literature...
- PUBLICATION BIAS IN META ANALYSES FOR MENTAL HEALTHMichael Borenstein; Fiscal Year: 2003DESCRIPTION (Applicant's abstract): The goal of this project is to develop software to address publication bias in meta analysis...
- Pooled Analyses of SNPs and Risk of Head & Neck CancerMia Hashibe; Fiscal Year: 2006..due to: i) low statistical power in detecting modest risk sequence variants, ii) false positive results, iii) publication bias, and iv) a moderate prior probability that each SNP individually confers substantial increase in risk...
- Two Methodological Problems in Psychotherapy ResearchScott Baldwin; Fiscal Year: 2004..First is publication bias. The proposed research will review psychotherapy meta-analyses to assess whether and how meta-analysts attend ..
- Multi-Site Longitudinal Analysis-Psychiatric Risk of SUDELIZABETH COSTELLO; Fiscal Year: 2005..and which depends on investigators' decision to publish on a particular topic; and it is not subject to "publication bias": the tendency to publish only "significant" findings...
- International Lung Cancer Consortium: Pooled analysis o*Paul Brennan; Fiscal Year: 2006..false positive results, (iii) failure to consider effect modifiers such as environmental exposures, and (iv) publication bias. Furthermore, examining the main effects of single modest risk sequence variants is an overly simplified ..
- Nutritional/Inflammatory Evaluation of Dialysis PatientsKamyar Kalantar Zadeh; Fiscal Year: 2005....
- Anti-Inflammatory and Anti-Oxidative Nutrition in Dialysis PatientsKamyar Kalantar Zadeh; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- COST EFFECTIVENESS OF GENETIC SCREENING FOR COLON CANCERScott Ramsey; Fiscal Year: 2002....
- A Genetic Screening Policy Model for Colorectal CancerScott Ramsey; Fiscal Year: 2006..The model will incorporate QOL information from Aim 2, along with family history, clinical, and screening information from the Seattle CFR. ..
- Pramipexole in Treatment-Resistant DepressionRoy Perlis; Fiscal Year: 2007..The proposed investigation and training program will provide critical skills, experience and data to aid the candidate in writing an R01 and becoming an independent investigator. ..
- Pharmacotherapy for Minor DepressionRobert Howland; Fiscal Year: 2004..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..
- DEALING WITH PUBLICATION BIAS IN META-ANALYSISNorma Terrin; Fiscal Year: 2004..Still, key methodological issues remain, including the problem of publication bias, which can threaten the results of any meta-analysis...
- Gene Expression in Inflammatory MyopathiesSteven Greenberg; Fiscal Year: 2005..This work may provide further diagnostic approaches to these disorders and contribute to the understanding of their pathogenesis. ..
- The Perception of Cancer Risk in Patients with Barrett's EsophagusNicholas Shaheen; Fiscal Year: 2007..The resultant study application will assess health-related quality of life, health-related anxiety and healthcare utilization as outcomes. [unreadable] [unreadable]..
- RANDOMIZED TRIAL OF FOLATE AND COLORECTAL ADENOMAEdward Giovannucci; Fiscal Year: 2003..abstract_text> ..
- Comprehensive Support for Alzheimer's Disease CaregiversJOSEPH GAUGLER; Fiscal Year: 2008..The proposed evaluation will provide detailed information on the potential of the ECS to serve as a model intervention for various family caregivers of Alzheimer?s patients in diverse geographic contexts. [unreadable]..
- DIET AND GENETIC INTERACTIONS IN PROSTATE CANCEREdward Giovannucci; Fiscal Year: 2001..The buccal brushings, along with providing the basis for the specific aims in this application, will allow for the rapid testing of future specific hypotheses. ..
- A Cancer Study Among Female Veterans in Texas, 1979-2001Sally Vernon; Fiscal Year: 2005..This research will further knowledge of the health needs of women veterans, serving to identify needed health services and to guide health policy, and will provide a basis for research agendas aimed at this growing occupational cohort. ..
- Higher Throughput Behavioral Screening of Cognitive EnhancersDaniela Brunner; Fiscal Year: 2007..unreadable] [unreadable]..
- Early Identification of Adverse Reactions to HerbsStephen Bent; Fiscal Year: 2007..Ultimately, this research strives to identify improved methods for the early detection of adverse events, providing patients with a safer environment to achieve the potential benefits of herbal products. ..
- CVD Predictors of Cognitive Function Trajectory over 20 YearsElizabeth L Barrett Connor; Fiscal Year: 2010..This information is important given the aging of the population, the fact that CVD risk factors are modifiable, and because the maintenance of cognitive function is an essential component of healthy aging. ..
- Raloxifene in Women with AD: Randomized Controlled TrialVICTOR HENDERSON; Fiscal Year: 2007..It is anticipated that findings from this pilot study will provide useful guidance to plan and conduct future studies of raloxifene in women with mild to moderate symptoms of dementia due to AD. ..
- Outcomes of Sleep Disorders in Older MenElizabeth Barrett Connor; Fiscal Year: 2007..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
- Statistical Methods for Identifying Clonal TumorsColin B Begg; Fiscal Year: 2011....
- Capitalizing upon Genetic HeterogeneityDavid Redden; Fiscal Year: 2007..Redden have been proposed. At the end of this five year research initiative, Dr. Redden will be well positioned to conduct cross-disciplinary research in obesity, genetics, and statistics. ..
- Lay and Expert Models of Gene-Environment InteractionCeleste Condit; Fiscal Year: 2008..This will help recipients to adopt behaviors that will better stave off the risks identified by the tests. [unreadable] [unreadable] [unreadable]..
- Relation of Alignment and Other Risk Factors to Knee OADAVID TOBIN FELSON; Fiscal Year: 2010....
- Structural Correlates of Knee PainDavid Felson; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Effects of Light at Night on Circadian System in NursesEva Schernhammer; Fiscal Year: 2008..abstract_text> ..
- FONDAPARINUM IN CHILDREN WITH THROMBOSISGuy Young; Fiscal Year: 2007..Pharmacokinetic analyses as well as safety and efficacy determinations will be made which will provide valuable information on this new anticoagulant for pediatric patients. [unreadable] [unreadable]..
- EVALUATING VOUCHER-BASED CONTINGENCIES IN A DRUG COURTMichael Prendergast; Fiscal Year: 2003..4) To provide a qualitative assessment of the impact on court operations and costs of introducing a voucher-based contingency management protocol into a drug court treatment program. ..
- A Method for Validating Gene - Disease AssociationsColin Begg; Fiscal Year: 2004..abstract_text> ..
- Comprehensive Database on Spirituality and HealthJeanette Ezzo; Fiscal Year: 2004..Phase II will focus on comprehensively populating the database with a significantly larger and more comprehensive set of research citations and related materials and migrating to a fully functional website, SpiritLit.com. ..
- WOMEN VETERANS AND BREAST CANCER SCREENINGSally Vernon; Fiscal Year: 2003..The infrastructure is in place to institutionalize the intervention should it prove to be effective. ..
- Chronic Illness Exercise Interventions: A Meta-AnalysisVicki Conn; Fiscal Year: 2004..The compelling importance and broad scope of this work make funding necessary to achieve these important aims. ..
- Geographic Tools for Surveillance and Study of DiseaseDaniel Wartenberg; Fiscal Year: 2003..We will explore methods for imputing values and adjusting for edge effects using methods including Markov Chain Monte Carlo simulations. ..
- DIETARY FAT, PLASMA LIPIDS AND OTHER CHD RISK FACTORS.Alice Lichtenstein; Fiscal Year: 2003..The investigators state that data derived from the proposed studies could contribute to the database on which to formulate more specific public health recommendations regarding the variables described. ..
- Endogenous/Exogenous Sex Hormones & CHD Risk FactorsElizabeth Barrett Connor; Fiscal Year: 2003..These observations may aid in deciding whether individual women should use HRT and, if so, which regimen would provide the most benefit with the least risk. ..
- ASTHMA CLINICAL RESEARCH NETWORKVernon Chinchilli; Fiscal Year: 2002....
- Conference--ISEE 16th Annual MeetingDaniel Wartenberg; Fiscal Year: 2004..ISEE provides a variety of forums for discussion, critical reviews, collaborations and education issues for environmental exposures and their human health effects. ..
- Animal Models of Schizophrenia: NRG-erbB FunctionDaniela Brunner; Fiscal Year: 2005..Such models will allow testing of antipsychotic treatments based on novel and standard chemistries, and will define the preferred developmental time and drug regime for an optimal therapeutic treatment. ..
- Epidemiologic Case-control Study of Barrett's EsophagusNicholas Shaheen; Fiscal Year: 2005..Finally, by comparing subjects with Barrett's to controls with reflux, and controlling for severs of reflux, the impact of a Barrett's diagnosis on quality of life and psychological stress may be seen. ..
- Epidemiologic Parameters of Rare Cancer Risk FactorsColin Begg; Fiscal Year: 2005..All of these aims are motivated by an international study of the genetic epidemiology of melanoma that is currently in progress. ..
- Center for the Study of ViolenceCraig Anderson; Fiscal Year: 2004..abstract not provided ..
- EXERCISE, DISABILITY, OSTEOARTHRITIS AND COSTSJames Fries; Fiscal Year: 2006..They further state that the overall project objective is to understand how improvements in exercise and other risk factor status may retard functional decline and reduce the need for medical care. ..
- Quality of Care for Adolescent Suicide AttemptersJeffrey Bridge; Fiscal Year: 2008..Together, these projects will inform the design of a future R01 proposal aimed at studying quality of care factors and outcome for at-risk youth across a broader range of service providers and treatment settings. ..
- Tailored Interactive Intervention to Increase CRC ScreenSally Vernon; Fiscal Year: 2006..Telephone follow-up and medical record review will be conducted 6 months after delivery of the intervention to ascertain completion of CRCS. ..
- RESEARCH ETHICS IN SCHIZOPHRENIAWilliam Carpenter; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Race and Public Communication about Human VariationCeleste Condit; Fiscal Year: 2003..The project will focus on the concerns of African Americans about discrimination and genetics and on attitudes about African Americans and genetics held by European Americans and the general population. ..
- TREATMENT OF NEGATIVE SYMPTOMS & COGNITIVE IMPAIRMENTSWilliam Carpenter; Fiscal Year: 2003..The study will provide new information on the efficacy of d- cyclosporine and glycine for both persistent primary and secondary negative symptoms and its effect on cognitive functioning. ..
- A Pilot Trial of Oral Melatonin Supplementation in Breast Cancer SurvivorsEva Schernhammer; Fiscal Year: 2007..This pilot data could lay the groundwork for a large scale trial to assess the chemopreventive potential of melatonin in women, both with and without a personal history of breast cancer. [unreadable] [unreadable] [unreadable]..
- National Assessment of the Mortality and Morbidity Effects of Tropospheric OzoneMichelle L Bell; Fiscal Year: 2010..The goal of this work is to provide policy-makers, scientists, and the public with a better understanding of how ozone affects health in order to aid more effective decisions regarding protection of human health. ..
- Clock Genes, Night Work, and Breast Cancer RiskEva Schernhammer; Fiscal Year: 2008..The results from this study could help identify individuals who are more susceptible to night work than others, based on their genetic profile. ..
- Family Involvement /Resident Psychosocial Status in LTCJOSEPH GAUGLER; Fiscal Year: 2002..abstract_text> ..
- Training for US Cochrane Contributors and OthersKay Dickersin; Fiscal Year: 2006..The applicant will collaborate and partner with investigators associated with the EPCs in all stages of the project. [unreadable] [unreadable]..
- St. John's Wort for tobacco cessationAmit Sood; Fiscal Year: 2006..This study is anticipated to provide the data needed to develop a larger randomized controlled clinical trial submitted through the R01 funding mechanism to NCCAM. [unreadable] [unreadable]..
- Management Decisions in Financial Conflicts of InterestLisa Bero; Fiscal Year: 2002..Our findings will allow us to develop a framework for decision-making regarding conflict identification and management. ..
- IONDT FOLLOW-UP STUDYKay Dickersin; Fiscal Year: 2002....
- Information Technologies to Improve Patient AdherenceRaymond Ownby; Fiscal Year: 2006..Ownby to develop as a clinical researcher capable of carrying out patient-oriented research studies and give him additional tools in applied cognitive aging and human factors research, especially applications of emerging information. ..
- Glycemic Index and Metabolic SyndromeANASTASSIOS PITTAS; Fiscal Year: 2005..abstract_text> ..
- Gabapentin for Smoking AbstinenceAmit Sood; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- A Qualitative Study of Editorial Decision-MakingLisa Bero; Fiscal Year: 2003..abstract_text> ..
- Translating Evidence to Quality Care: Getting the Message to Your ConstituencyKay Dickersin; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Data Coordinating Center for Sleep Heart HealthMarie Diener West; Fiscal Year: 2007..abstract_text> ..