pregnancy rate

Summary

Summary: The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.

Top Publications

  1. ncbi Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE
    J de Mouzon
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 25:1851-62. 2010
  2. ncbi Assisted reproductive technology in Europe, 2004: results generated from European registers by ESHRE
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 23:756-71. 2008
  3. ncbi The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count
    Simone L Broer
    Department of Reproductive Medicine, Division of Obstetrics, Neonatology, and Gynecology, University Medical Center, Utrecht, The Netherlands
    Fertil Steril 91:705-14. 2009
  4. pmc Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function
    David Barad
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    J Assist Reprod Genet 24:629-34. 2007
  5. ncbi A lower ongoing pregnancy rate can be expected when GnRH agonist is used for triggering final oocyte maturation instead of HCG in patients undergoing IVF with GnRH antagonists
    E M Kolibianakis
    Centre of Reproductive Medicine, Dutch Speaking Brussels Free University, Belgium
    Hum Reprod 20:2887-92. 2005
  6. ncbi Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer
    D K Gardner
    Colorado Center for Reproductive Medicine, Englewood, Colorado, USA
    Fertil Steril 73:1155-8. 2000
  7. ncbi Highly efficient vitrification method for cryopreservation of human oocytes
    Masashige Kuwayama
    Kato Ladies Clinic, Tokyo, Japan
    Reprod Biomed Online 11:300-8. 2005
  8. ncbi Clomiphene citrate or letrozole for ovulation induction in women with polycystic ovarian syndrome: a prospective randomized trial
    Ahmed Badawy
    Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt
    Fertil Steril 92:849-52. 2009
  9. ncbi Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE)
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60 B 1852, Grimbergen, Belgium
    Hum Reprod 24:1267-87. 2009
  10. ncbi Comparing anti-Müllerian hormone (AMH) and follicle-stimulating hormone (FSH) as predictors of ovarian function
    David H Barad
    Center for Human Reproduction, New York, New York 10021, USA
    Fertil Steril 91:1553-5. 2009

Detail Information

Publications366 found, 100 shown here

  1. ncbi Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE
    J de Mouzon
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 25:1851-62. 2010
    ..In this 10th European IVF-monitoring (EIM) report, the results of assisted reproductive techniques from treatments initiated in Europe during 2006 are presented. Data were mainly collected from existing national registers...
  2. ncbi Assisted reproductive technology in Europe, 2004: results generated from European registers by ESHRE
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 23:756-71. 2008
    ..European results of assisted reproductive techniques from treatments initiated during 2004 are presented in this eighth report...
  3. ncbi The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count
    Simone L Broer
    Department of Reproductive Medicine, Division of Obstetrics, Neonatology, and Gynecology, University Medical Center, Utrecht, The Netherlands
    Fertil Steril 91:705-14. 2009
    ..To assess the value of antimullerian hormone (AMH) as a test to predict poor ovarian response and pregnancy occurrence after IVF and to compare it with the performance of the antral follicle count (AFC)...
  4. pmc Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function
    David Barad
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    J Assist Reprod Genet 24:629-34. 2007
    ..We assessed the role of DHEA supplementation on pregnancy rates in women with diminished ovarian function...
  5. ncbi A lower ongoing pregnancy rate can be expected when GnRH agonist is used for triggering final oocyte maturation instead of HCG in patients undergoing IVF with GnRH antagonists
    E M Kolibianakis
    Centre of Reproductive Medicine, Dutch Speaking Brussels Free University, Belgium
    Hum Reprod 20:2887-92. 2005
    ..However, the efficacy of this intervention in patients treated for IVF with GnRH antagonists remains to be assessed...
  6. ncbi Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer
    D K Gardner
    Colorado Center for Reproductive Medicine, Englewood, Colorado, USA
    Fertil Steril 73:1155-8. 2000
    ..To determine the relationship between blastocyst score and pregnancy outcome...
  7. ncbi Highly efficient vitrification method for cryopreservation of human oocytes
    Masashige Kuwayama
    Kato Ladies Clinic, Tokyo, Japan
    Reprod Biomed Online 11:300-8. 2005
    ..The results suggest that vitrification using the Cryotop is the most efficient method for human oocyte cryopreservation...
  8. ncbi Clomiphene citrate or letrozole for ovulation induction in women with polycystic ovarian syndrome: a prospective randomized trial
    Ahmed Badawy
    Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt
    Fertil Steril 92:849-52. 2009
    ..To compare the effects of letrozole (5 mg) and clomiphene citrate (100 mg) for ovulation induction in women with polycystic ovary syndrome (PCOS)...
  9. ncbi Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE)
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60 B 1852, Grimbergen, Belgium
    Hum Reprod 24:1267-87. 2009
    ..Results of assisted reproductive techniques from treatments initiated in Europe during 2005 are presented in this ninth report. Data were mainly collected from existing national registers...
  10. ncbi Comparing anti-Müllerian hormone (AMH) and follicle-stimulating hormone (FSH) as predictors of ovarian function
    David H Barad
    Center for Human Reproduction, New York, New York 10021, USA
    Fertil Steril 91:1553-5. 2009
    ..In 76 IVF cycles investigated, AMH was clearly superior in predicting IVF outcomes in comparison with FSH...
  11. ncbi Live birth chances in women with extremely low-serum anti-Mullerian hormone levels
    Andrea Weghofer
    Department of Obstetrics and Gynecology, Medical University Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Hum Reprod 26:1905-9. 2011
    ..To determine whether women with extremely low-serum anti-Mullerian hormone (AMH) levels (<0.1-0.4 ng/ml) still demonstrate live birth potential with assisted reproduction and whether such potential is age dependent...
  12. ncbi Closed blastocyst vitrification of biopsied embryos: evaluation of 100 consecutive warming cycles
    L Van Landuyt
    Centre for Reproductive Medicine, UZ Brussel, Laarbeeklaan 101, 1090 Jette, Belgium
    Hum Reprod 26:316-22. 2011
    ..The aim of this study was to analyse the outcome of closed blastocyst vitrification of embryos biopsied at the cleavage stage...
  13. ncbi Vitrification of human blastocysts with the Hemi-Straw carrier: application of assisted hatching after thawing
    P Vanderzwalmen
    Schoysman Infertility Management Foundation, AZ Jan Portaels, Gendarmeriestraat 65, 1800 Vilvoorde, Belgium
    Hum Reprod 18:1504-11. 2003
    ..The present study was undertaken to examine the usefulness of both vitrification and assisted hatching (AH) on blastocysts that originate from embryos showing different qualities during their cleavage stage...
  14. ncbi Anti-Müllerian hormone (AMH) defines, independent of age, low versus good live-birth chances in women with severely diminished ovarian reserve
    Norbert Gleicher
    The Center for Human Reproduction and Foundation for Reproductive Medicine, New York, New York 10021, USA
    Fertil Steril 94:2824-7. 2010
    ..04 ng/mL but significantly increased at AMH 0.41-1.05 ng/mL, resulting in similarly low live-birth rates at all AMH levels ≤1.05 ng/mL and significantly improved live-birth rates at AMH ≥1.06 ng/mL...
  15. pmc Starting and resulting testosterone levels after androgen supplementation determine at all ages in vitro fertilization (IVF) pregnancy rates in women with diminished ovarian reserve (DOR)
    Norbert Gleicher
    Center for Human Reproduction, New York, NY 10021, USA
    J Assist Reprod Genet 30:49-62. 2013
    ....
  16. ncbi Radical vaginal trachelectomy as a fertility-sparing procedure in women with early-stage cervical cancer-cumulative pregnancy rate in a series of 123 women
    J H Shepherd
    The Gynaecological Cancer Centre, St Bartholomew s Hospital, West Smithfield, London, UK
    BJOG 113:719-24. 2006
    ..To analyse the fertility rates, complications and recurrences in a group of women who have undergone radical vaginal trachelectomy and pelvic lymphadenectomy for early-stage cervical cancer...
  17. pmc Lessons from elective in vitro fertilization (IVF) in, principally, non-infertile women
    Norbert Gleicher
    Center for Human Reproduction, New York, NY 10021, USA
    Reprod Biol Endocrinol 10:48. 2012
    ..Since IVF outcome in women with infertility are always influenced by underlying causes of infertility, a study on non-infertile women may offer new insights...
  18. ncbi Understanding maternal contributions to fertility in recipient cattle: development of herds with contrasting pregnancy rates
    W H McMillan
    AgResearch Ruakura, Hamilton, New Zealand
    Anim Reprod Sci 57:127-40. 1999
    ..Heifers were ranked on their aggregate pregnancy rate performance, and the highest (High) and lowest (Low) 25 were retained...
  19. ncbi Ovarian stimulation by concomitant administration of cetrorelix acetate and HMG following Diane-35 pre-treatment for patients with polycystic ovary syndrome: a prospective randomized study
    Jiann Loung Hwang
    Department of Obstetrics and Gynecology, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
    Hum Reprod 19:1993-2000. 2004
    ..We proposed a stimulation protocol incorporating Diane-35 and GnRH antagonist (Diane/cetrorelix protocol) and compared it with the GnRH agonist long protocol for PCOS patients...
  20. ncbi Circulating progesterone levels and ongoing pregnancy rates in controlled ovarian stimulation cycles for in vitro fertilization: analysis of over 4000 cycles
    E Bosch
    Department of Reproduction, Instituto Valenciano de Infertilidad, University of Valencia, Plaza de la Policia Local, 3, 46015 Valencia, Spain
    Hum Reprod 25:2092-100. 2010
    ..Efforts to resolve this question have been impeded by the various assays used to measure progesterone and the different, arbitrary threshold values for defining 'high' progesterone levels...
  21. ncbi What is the preferred GnRH analogue for polycystic ovary syndrome patients undergoing controlled ovarian hyperstimulation for in vitro fertilization?
    Raoul Orvieto
    Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel
    Fertil Steril 91:1466-8. 2009
    ..The PCOS patients undergoing COH using the GnRH agonist protocol (n = 50) showed a significantly higher pregnancy rate (36% vs. 19.6%, respectively), compared with the GnRH antagonist protocol (n = 102).
  22. ncbi Blastocyst culture is associated with an elevated incidence of monozygotic twinning after single embryo transfer
    Satoshi Kawachiya
    Kato Ladies Clinic, Tokyo, Japan
    Fertil Steril 95:2140-2. 2011
    ..04; 95% confidence interval, 1.29-4.48), whereas embryo freezing, type of stimulation protocol used, intracytoplasmic sperm injection fertilization, or zona removal did not influence its incidence...
  23. ncbi Factors predicting the cumulative outcome of IVF/ICSI treatment: a multivariable analysis of 2450 patients
    Q F Cai
    Reproductive Medicine Center, Women and Children s Hospital of Guangdong Province, Guangzhou 510000, PR China
    Hum Reprod 26:2532-40. 2011
    ....
  24. pmc Stress reduces conception probabilities across the fertile window: evidence in support of relaxation
    Germaine M Buck Louis
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland 20852, USA
    Fertil Steril 95:2184-9. 2011
    ..To assess salivary stress biomarkers (cortisol and α-amylase) and female fecundity...
  25. ncbi Can dopamine agonists reduce the incidence and severity of OHSS in IVF/ICSI treatment cycles? A systematic review and meta-analysis
    Mohamed A F M Youssef
    Department of Obstetrics and Gynaecology, Cairo University, Cairo, Egypt
    Hum Reprod Update 16:459-66. 2010
    ..Recently, dopamine agonists were proposed as a prophylactic treatment for ovarian hyperstimulation syndrome (OHSS) in women at high risk in IVF/ICSI treatment cycles...
  26. ncbi Oocyte karyotyping by comparative genomic hybridization [correction of hybrydization] provides a highly reliable method for selecting "competent" embryos, markedly improving in vitro fertilization outcome: a multiphase study
    Geoffrey Sher
    Sher Institute for Reproductive Medicine, Las Vegas, Nevada 89109, USA
    Fertil Steril 87:1033-40. 2007
    ....
  27. ncbi Evaluating the performance of serum antimullerian hormone concentration in predicting the live birth rate of controlled ovarian stimulation and intrauterine insemination
    Hang Wun Raymond Li
    Centre of Assisted Reproduction and Embryology, Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Fertil Steril 94:2177-81. 2010
    ..To evaluate the role of serum antimullerian hormone (AMH) concentration in predicting live birth outcome in controlled ovarian stimulation and intrauterine insemination (IUI)...
  28. ncbi Management of poor responders: can outcomes be improved with a novel gonadotropin-releasing hormone antagonist/letrozole protocol?
    William B Schoolcraft
    Colorado Center for Reproductive Medicine, Englewood, Colorado, USA
    Fertil Steril 89:151-6. 2008
    ..To compare the efficacy of a microdose GnRH agonist flare (ML) with a GnRH antagonist/letrozole (AL) protocol before IVF-ET in poor responders...
  29. ncbi Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis
    Kalliopi E Loutradi
    Unit for Human Reproduction, 1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, Thessaloniki, Greece
    Fertil Steril 90:186-93. 2008
    ..the literature systematically in order to identify prospective comparative trials answering the following question: Is vitrification of human embryos associated with a higher postthawing survival rate as compared with slow freezing?..
  30. pmc Serum anti-Müllerian hormone predicts ovarian response and cycle outcome in IVF patients
    Cheng Hsuan Wu
    Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, 500 Taiwan, Republic of China
    J Assist Reprod Genet 26:383-9. 2009
    ..This prospective study was designed to investigate whether anti-Müllerian hormone (AMH) levels at basal and ovulation triggering day are associated with ovarian response and pregnancy outcome for in vitro fertilization (IVF)...
  31. ncbi A randomized trial of superovulation with two different doses of letrozole
    Raedah Al-Fadhli
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Fertil Steril 85:161-4. 2006
    ..The aim of this study was to evaluate the effects of either a 2.5-mg or a 5-mg daily dose of letrozole in women undergoing superovulation and intrauterine insemination (IUI)...
  32. ncbi Aromatase inhibitors for female infertility: a systematic review of the literature
    Nikolaos P Polyzos
    PACMeR Panhellenic Association for Continual Medical Research, Section of Obstetrics and Gynaecology and Public Health, Athens 10438, Greece
    Reprod Biomed Online 19:456-71. 2009
    ..If solid data from future large adequately powered randomized trials support current evidence regarding efficacy and safety, AI might offer a new treatment choice for infertile women...
  33. ncbi Sperm nuclear vacuoles, as assessed by motile sperm organellar morphological examination, are mostly of acrosomal origin
    O Kacem
    Service d Histologie Embryologie Biologie de la Reproduction, Hopital Cochin, AP HP, 123, Bd Port Royal 75013 Paris, Universite Paris Descartes, France
    Reprod Biomed Online 20:132-7. 2010
    ....
  34. ncbi Slow freezing, vitrification and ultra-rapid freezing of human embryos: a systematic review and meta-analysis
    Faten F AbdelHafez
    Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, OH, USA
    Reprod Biomed Online 20:209-22. 2010
    ..Primary outcomes were clinical pregnancy rate (CPR) and incidence of congenital abnormalities...
  35. ncbi Conventional testicular sperm extraction combined with the microdissection technique in nonobstructive azoospermic patients: a prospective comparative study
    Tahsin Turunc
    Department of Urology, Baskent University, Faculty of Medicine, Ankara, Turkey
    Fertil Steril 94:2157-60. 2010
    ..To perform conventional and microdissection testicular sperm extraction (TESE) at the same session and compare their effectiveness...
  36. ncbi Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization
    Emre Seli
    Department of Obstetrics, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Fertil Steril 90:2183-9. 2008
    ..To identify biomarkers associated with reproductive outcome using proton nuclear magnetic resonance ((1)H NMR) metabolomic profiling of embryo culture media...
  37. ncbi Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review
    P Donoso
    Reproductive Medicine Unit, Clinica Alemana, Vitacura 5951, Santiago, Chile
    Hum Reprod Update 13:539-49. 2007
    ..However, so far there appears to be no impact of the technique itself on success rates...
  38. ncbi A prospective study of stress among women undergoing in vitro fertilization or gamete intrafallopian transfer
    H Klonoff-Cohen
    Department of Family and Preventive Medicine, Division of Epidemiology, University of California San Diego, La Jolla, California 92093 0607, USA
    Fertil Steril 76:675-87. 2001
    ..To evaluate whether baseline or procedural stress during in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT) affects pregnancy or live birth delivery rates...
  39. ncbi Trends in the use of intracytoplasmic sperm injection in the United States
    Tarun Jain
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Illinois at Chicago College of Medicine, Chicago, IL 60612, USA
    N Engl J Med 357:251-7. 2007
    ..However, despite the added cost, uncertain efficacy, and potential risks of ICSI, its use has been extended to include some patients without documented male-factor infertility...
  40. ncbi Gonadotropin-releasing hormone agonists versus antagonists for controlled ovarian hyperstimulation in oocyte donors: a systematic review and meta-analysis
    Daniel Bodri
    Clinica Eugin, Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva, Universitat Autonoma de Barcelona, Barcelona, Spain
    Fertil Steril 95:164-9. 2011
    ..To compare GnRH agonists and antagonists in oocyte-donation IVF treatment cycles by a systematic review and meta-analysis of trials...
  41. ncbi Clinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration
    A Borini
    Tecnobios Procreazione, Via Dante 15 University of Bologna, 40125 Bologna, Italy
    Hum Reprod 21:512-7. 2006
    ..However, the clinical efficiency of these protocols has not been exhaustively explored and therefore remains controversial...
  42. ncbi Assisted reproductive technology in Europe, 2001. Results generated from European registers by ESHRE
    A Nyboe Andersen
    Hum Reprod 20:1158-76. 2005
    ..4 million, corresponding to 829 cycles per million inhabitants. For IVF, the clinical pregnancy rate per aspiration and per transfer was 25.1 and 29.0%, respectively. For ICSI, the corresponding rates were 26...
  43. ncbi GnRH agonist for triggering of final oocyte maturation: time for a change of practice?
    P Humaidan
    The Fertility Clinic, Skive Regional Hospital, Resenvej 25, Skive, Denmark
    Hum Reprod Update 17:510-24. 2011
    ..Therefore, the challenge has been to rescue the luteal phase. Studies now report a luteal phase rescue, with a reproductive outcome comparable to that seen after hCG triggering...
  44. ncbi A new era in ovulation induction
    Hananel Holzer
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Fertil Steril 85:277-84. 2006
    ..To evaluate the efficacy of aromatase inhibitors in ovulation induction, superovulation, and IVF...
  45. ncbi The morphology of human pronuclear embryos is positively related to blastocyst development and implantation
    L Scott
    The A R T Institute of Washington, Inc at Walter Reed Army Medical Center, Walter Reed Army Medical Center, Washington DC 20012, USA
    Hum Reprod 15:2394-403. 2000
    ..Zygote scoring can maintain pregnancy rates for both day 3 and day 5 transfers, increase implantation rates and reduce the numbers of embryos required to achieve a pregnancy...
  46. ncbi Cytokines and chemokines in follicular fluids and potential of the corresponding embryo: the role of granulocyte colony-stimulating factor
    N Ledee
    Service de Gynécologie Obstétrique et Médecine de la Reproduction et Service de cytogenétique et Biologie de la Reproduction, centre hospitalier intercommunal Poissy Saint Germain en Laye, Univ UVSQ, UPRES EA 2493, Poissy, France
    Hum Reprod 23:2001-9. 2008
    ..The cytokine/chemokine levels of individual follicular fluids (FFs) were measured to determine whether a biomarker could be linked to the developmental potential of the derived embryo...
  47. ncbi Effect of endometriosis on in vitro fertilization
    Kurt Barnhart
    Center for Reproductive Medicine and Surgery, University of Pennsylvania Medical Center and Health System, Philadelphia, Pennsylvania, USA
    Fertil Steril 77:1148-55. 2002
    ..To investigate the IVF outcome for patients with endometriosis...
  48. ncbi Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: a randomized prospective study
    A Wiser
    IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel
    Hum Reprod 25:2496-500. 2010
    ..The aim of this study was to evaluate the effect of dehydroepiandrosterone (DHEA) supplementation on in vitro fertilization (IVF) data and outcomes among poor-responder patients...
  49. ncbi Relevance of anti-Mullerian hormone measurement in a routine IVF program
    C Gnoth
    Center for Family Planning, Gynecological Endocrinology and Reproductive Medicine, Rheydter Strasse 143, 41515 Grevenbroich, Germany
    Hum Reprod 23:1359-65. 2008
    ..This prospective study was conducted to evaluate the relevance of AMH in a routine IVF program...
  50. ncbi Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial
    Monica Antinori
    RAPRUI Day Hospital International Associated Research Institute for Human Reproduction, Via Timavo 2, Rome, Italy
    Reprod Biomed Online 16:835-41. 2008
    ..The data showed that IMSI resulted in a higher clinical pregnancy rate (39.2% versus 26.5%; P = 0.004) than ICSI when applied to severe male infertility cases...
  51. ncbi Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiol
    André Hazout
    ART Unit Eylau la Muette, Clinic La Muette, Paris, France
    Fertil Steril 82:1323-9. 2004
    ..To test the hypothesis that the concentration of early follicular phase serum antimullerian hormone (AMH) or mullerian-inhibiting substance (MIS) is a useful marker of ovarian response and assisted reproductive technology (ART) outcome...
  52. ncbi A randomized single-blind controlled trial of letrozole as a low-cost IVF protocol in women with poor ovarian response: a preliminary report
    S K Goswami
    Institute of Reproductive Medicine, Salt Lake, Kolkata 700091, India
    Hum Reprod 19:2031-5. 2004
    ..Use of letrozole, a selective inhibitor of aromatase, reduces the gonadotrophin dose required to induce follicular maturation. We evaluated whether incorporation of letrozole could be an effective low-cost IVF protocol for poor responders...
  53. pmc Pregnancy prediction models and eSET criteria for IVF patients--do we need more information?
    Lars D M Ottosen
    The Fertility Clinic, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Skejby Sygehus, Brendstrupgaardsvej, DK 8200, Arhus N, Denmark
    J Assist Reprod Genet 24:29-36. 2007
    ..The purpose of the present study was to evaluate statistical prediction models and simple allocation criteria, based on predictors for pregnancy, as tools to identify a good prognosis group in a possible eSET setting...
  54. pmc Embryo development of fresh 'versus' vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study
    Laura Rienzi
    G E N E R A Centre for Reproductive Medicine, Clinica Valle Giulia, Via De Notaris 2b, Rome, Italy
    Hum Reprod 25:66-73. 2010
    ..Vitrification has been recently proposed as an effective procedure for this purpose...
  55. ncbi Influence of atmospheric versus reduced oxygen concentration on development of human blastocysts in vitro: a prospective study on sibling oocytes
    B Kovacic
    Department of Reproductive Medicine, University Clinical Centre Maribor, Ljubljanska 5, SI 2000 Maribor, Slovenia
    Reprod Biomed Online 17:229-36. 2008
    ..9 versus 11.4%; P < 0.01). The ratio of successful embryo development to optimal blastocyst stage on day 5 of culture, calculated for two oxygen concentrations, was 2.1 for IVF and 1.7 for ICSI, in favour of lower oxygen tension...
  56. ncbi Antimüllerian hormone in gonadotropin releasing-hormone antagonist cycles: prediction of ovarian response and cumulative treatment outcome in good-prognosis patients
    Joan Carles Arce
    Reproductive Health, Ferring Pharmaceuticals A S, Copenhagen, Denmark
    Fertil Steril 99:1644-53. 2013
    ....
  57. ncbi Interaction between season and culture with insulin-like growth factor-1 on survival of in vitro produced embryos following transfer to lactating dairy cows
    J Block
    Department of Animal Sciences, University of Florida, Gainesville, FL 32611 0910, USA
    Theriogenology 67:1518-29. 2007
    ..There was a tendency (P<0.09) for an interaction between embryo treatment and season for pregnancy rate at Day 21; this interaction was significant at Days 30 and 45 (P<0.02)...
  58. ncbi Couples offered free assisted reproduction treatment have a very high chance of achieving a live birth within 4 years
    Yechezkel Lande
    Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel
    Fertil Steril 95:568-72. 2011
    ..To assess the long-term success rate among couples with primary infertility offered unrestricted, free in vitro fertilization (IVF) treatments...
  59. ncbi Intrauterine injection of human chorionic gonadotropin before embryo transfer significantly improves the implantation and pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection: a prospective randomized study
    Ragaa Mansour
    The Egyptian IVF ET Center, Cairo, Egypt
    Fertil Steril 96:1370-1374.e1. 2011
    ..To investigate the value of intrauterine injection of human chorionic gonadotropin (hCG) before embryo transfer (ET)...
  60. ncbi Spermatogenesis affects the outcome of ICSI for azoospermic patients rather than sperm retrieval method
    Xiaojin He
    Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
    Syst Biol Reprod Med 56:457-64. 2010
    ..This study indicates that defective spermatogenesis affects the ICSI clinical outcome of azoospermic patients rather than the sperm retrieval methods...
  61. ncbi Evidence of impaired endometrial receptivity after ovarian stimulation for in vitro fertilization: a prospective randomized trial comparing fresh and frozen-thawed embryo transfer in normal responders
    Bruce S Shapiro
    Fertility Center of Las Vegas, Las Vegas, Nevada, USA
    Fertil Steril 96:344-8. 2011
    ..To compare success rates between fresh ETs after ovarian stimulation and frozen-thawed ETs (FET) after artificial endometrial preparation, to compare endometrial receptivity...
  62. ncbi The effect of coenzyme Q₁₀ supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis, Private Clinic Specialized in Urological and Andrological Genetics, PO Box 19395 1849, Tehran, Iran
    Int Urol Nephrol 44:689-700. 2012
    ..In present study, we evaluated the effects of coenzyme CoQ(10) supplementation on semen parameters and pregnancy rates in infertile men with idiopathic OAT...
  63. ncbi Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis
    Evangelos G Papanikolaou
    Centre for Reproductive Medicine, University Hospital, Vrije Univestiteit Brussel Free University of Brussels, Laarbeeklaaan 101, B 1090 Brussels, Belgium
    Hum Reprod 23:91-9. 2008
    ..Both cleavage-stage and blastocyst-stage embryo transfer policies have advantages and drawbacks. The number of embryos transferred, however, is a crucial parameter that needs to be considered before attempting any comparison...
  64. ncbi How to improve the probability of pregnancy in poor responders undergoing in vitro fertilization: a systematic review and meta-analysis
    Dimitra Kyrou
    First Department of Obstetrics and Gynecology, Unit for Human Reproduction, Papageorgiou General Hospital, Thessaloniki, Greece
    Fertil Steril 91:749-66. 2009
    ..To systematically review the literature to identify randomized controlled trials, which evaluate interventions aiming to improve the probability of pregnancy in poor responders undergoing in vitro fertilization (IVF)...
  65. ncbi Steroid receptor expression in late follicular phase endometrium in GnRH antagonist IVF cycles is already altered, indicating initiation of early luteal phase transformation in the absence of secretory changes
    Evangelos G Papanikolaou
    University Hospital, Dutch Speaking Brussels Free University, AZ VUB, Centre for Reproductive Medicine, Laarbeeklaaan 101, 1090 Jette, Brussels, Belgium
    Hum Reprod 20:1541-7. 2005
    ....
  66. ncbi Embryo loss in cattle between Days 7 and 16 of pregnancy
    D K Berg
    AgResearch, Ruakura Campus, Hamilton, New Zealand
    Theriogenology 73:250-60. 2010
    ..05; winter-spring, P<0.001). Lastly, transuterine migration in cattle, when transferring multiple embryos, commenced at Day 14 (4%) and had occurred in all recipients by Day 16 (38% of embryos found contralaterally)...
  67. ncbi Egg production predicts a doubling of in vitro fertilization pregnancy rates even within defined age and ovarian reserve categories
    Melissa C Yih
    The Center for Reproductive Medicine and Infertility Weill Medical College of Cornell University, New York, New York, USA
    Fertil Steril 83:24-9. 2005
    ..To examine the age-independent association of ovarian response and IVF outcome in women with normal and abnormal ovarian reserve...
  68. pmc Clinical benefit of metaphase I oocytes
    Leen Vanhoutte
    Infertility Centre, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Reprod Biol Endocrinol 3:71. 2005
    ..We studied the benefit of using in vitro matured metaphase I (MI) oocytes for ICSI in patients with a maximum of 6 mature metaphase II (MII) oocytes at retrieval...
  69. ncbi Prediction of pregnancy rate by blastocyst morphological score and age, based on 1,488 single frozen-thawed blastocyst transfer cycles
    Sakae Goto
    Hanabusa Women s Clinic, Kobe, Japan
    Fertil Steril 95:948-52. 2011
    To present an estimation of the pregnancy rate after IVF or intracytoplasmic sperm injection stratified by blastocyst morphology and age.
  70. ncbi Timing intercourse to achieve pregnancy: current evidence
    Joseph B Stanford
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City 84108, USA
    Obstet Gynecol 100:1333-41. 2002
    ..Proper information given early in the course of trying to achieve pregnancy is likely to reduce time to conception for many couples, and also to reduce unnecessary intervention and cost...
  71. ncbi Preovulatory progesterone concentration associates significantly to follicle number and LH concentration but not to pregnancy rate
    Claus Yding Andersen
    Laboratory of Reproductive Biology, University Hospital of Copenhagen, University of Copenhagen, Section 5712, Blegdamsvej 9, DK 2100 Copenhagen, Copenhagen, Denmark
    Reprod Biomed Online 23:187-95. 2011
    ..was no significant association between the late-follicular-phase progesterone concentration and the clinical pregnancy rate. However, progesterone concentration was strongly associated with the number of follicles and retrieved ..
  72. pmc A double-blind, non-inferiority RCT comparing corifollitropin alfa and recombinant FSH during the first seven days of ovarian stimulation using a GnRH antagonist protocol
    P Devroey
    Center for Reproductive Medicine, UZ Brussel, Brussels, Belgium
    Hum Reprod 24:3063-72. 2009
    ..A single injection of corifollitropin alfa may replace seven daily gonadotrophin injections during the first week of ovarian stimulation...
  73. ncbi Artificial shrinkage of blastocoeles using either a micro-needle or a laser pulse prior to the cooling steps of vitrification improves survival rate and pregnancy outcome of vitrified human blastocysts
    T Mukaida
    Hiroshima HART Clinic, Naka ku, Hiroshima, Japan
    Hum Reprod 21:3246-52. 2006
    ..Therefore, we evaluated the effectiveness of artificial shrinkage (AS) of blastocoeles before vitrification, on increasing the survival rate of vitrified blastocysts...
  74. ncbi Ovulation induction management of PCOS
    David S Guzick
    University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Clin Obstet Gynecol 50:255-67. 2007
    ..If there is no pregnancy despite several cycles of successful ovulation induction, gonadotropin treatment should be considered, in which case in vitro fertilization is recommended as the safest and most effective strategy...
  75. ncbi Prospects for improving reproductive performance through genetic selection
    Kent A Weigel
    Department of Dairy Science, University of Wisconsin, 1675 Observatory Drive, Madison, WI 53706, USA
    Anim Reprod Sci 96:323-30. 2006
    ..indirect selection for longevity or body condition score, or by direct selection for traits such as daughter pregnancy rate. Most leading dairy countries have implemented genetic evaluation systems for female fertility in the past ..
  76. pmc Individualised controlled ovarian stimulation (iCOS): maximising success rates for assisted reproductive technology patients
    Ernesto Bosch
    Instituto Valenciano de Infertilidad, Valencia, Spain
    Reprod Biol Endocrinol 9:82. 2011
    ....
  77. ncbi Triggering final oocyte maturation using different doses of human chorionic gonadotropin: a randomized pilot study in patients with polycystic ovary syndrome treated with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating horm
    Efstratios M Kolibianakis
    Centre for Reproductive Medicine, Vrije Universiteit Brussel, Brussels, Belgium
    Fertil Steril 88:1382-8. 2007
    ..To evaluate the effect of different human chorionic gonadotropin (hCG) doses on the ongoing pregnancy rates in patients with polycystic ovary syndrome (PCOS)...
  78. pmc Human cleavage-stage embryo vitrification is comparable to slow-rate cryopreservation in cycles of assisted reproduction
    Martin Graham Wilding
    Centro Fecondazione Assistita, Clinica Villa del Sole, Napoli, Italy
    J Assist Reprod Genet 27:549-54. 2010
    ..To compare embryo survival, pregnancy and implantation rates after cryopreservation of human cleavage-stage embryos with slow-rate cryopreservation or vitrification...
  79. ncbi Prolongation of the follicular phase in in vitro fertilization results in a lower ongoing pregnancy rate in cycles stimulated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonists
    Efstratios M Kolibianakis
    Centre for Reproductive Medicine, Dutch Speaking Brussels Free University, Brussels, Belgium
    Fertil Steril 82:102-7. 2004
    ..To assess the effect of altering the timing of hCG administration on ongoing pregnancy rates in patients stimulated with recombinant FSH (rec-FSH) and GnRH antagonists for IVF...
  80. ncbi Anxiety and depression have no influence on the cancellation and pregnancy rates of a first IVF or ICSI treatment
    A M E Lintsen
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Hum Reprod 24:1092-8. 2009
    ..This study aimed to determine the influences of anxiety and depression before and during IVF or ICSI treatment on the cancellation and pregnancy rates of inductees...
  81. ncbi Levels of follicular G-CSF and interleukin-15 appear as noninvasive biomarkers of subsequent successful birth in modified natural in vitro fertilization/intracytoplasmic sperm injection cycles
    Nathalie Ledee
    INSERM U782, University Paris Sud, and AP HP, Service d Histologie, Embryologie, cytogenetique, HôpitalAntoine Béclère, Clamart, France
    Fertil Steril 95:94-8. 2011
    ..The modified natural IVF/intracytoplasmic sperm injection (ICSI) cycle was used as an experimental model by measuring levels of cytokines, chemokines, and growth factors in individual follicular fluids (FF)...
  82. ncbi Effect of androgen supplementation or modulation on ovarian stimulation outcome in poor responders: a meta-analysis
    Sesh Kamal Sunkara
    Assisted Conception Unit, Guy s Hospital, St Thomas Street, London, UK
    Reprod Biomed Online 22:545-55. 2011
    ..The main outcome measure was clinical pregnancy rate. The secondary outcome measures were dose and duration of gonadotrophin use, cycles cancelled before oocyte ..
  83. ncbi Effect of ovarian stimulation with recombinant follicle-stimulating hormone, gonadotropin releasing hormone antagonists, and human chorionic gonadotropin on endometrial maturation on the day of oocyte pick-up
    Efstratios Kolibianakis
    Centre for Reproductive Medicine, Dutch Speaking Brussels Free University, Brussels, Belgium
    Fertil Steril 78:1025-9. 2002
    ..To assess the effect of ovarian stimulation with recombinant FSH, GnRH antagonists, and hCG on endometrial maturation on the day of oocyte pick-up...
  84. ncbi Selection of first in vitro fertilization cycle stimulation protocol for good prognosis patients: gonadotropin releasing hormone antagonist versus agonist protocols
    Erika B Johnston-MacAnanny
    Wake Forest University Center for Reproductive Medicine, Winston Salem, North Carolina, USA
    J Reprod Med 56:12-6. 2011
    ....
  85. ncbi Strategies to prevent unintended pregnancy: increasing use of long-acting reversible contraception
    P D Blumenthal
    Department of Obstetrics and Gynecology, Stanford University, Stanford, CA 94305 5317, USA
    Hum Reprod Update 17:121-37. 2011
    ..In this review we aim to discuss the role of LARC methods and importance of contraceptive counseling in reducing unintended pregnancy rates...
  86. ncbi Relationship between hyaluronic acid binding assay and outcome in ART: a pilot study
    Martine Nijs
    Genk Institute for Fertility Technology, Ziekenhuis Oost Limburg, Genk, Belgium
    Andrologia 42:291-6. 2010
    ..Outcome measures studied were fertilisation rate, embryo quality, ongoing pregnancy rate and cumulative pregnancy rate...
  87. ncbi Vitrified-warmed blastocyst transfer cycles yield higher pregnancy and implantation rates compared with fresh blastocyst transfer cycles--time for a new embryo transfer strategy?
    Dandan Zhu
    IVF Program, Nanjing Maternity and Child Health Hospital, Nanjing Medical University, Jiangsu, People s Republic of China
    Fertil Steril 95:1691-5. 2011
    ..To compare the clinical outcome of fresh versus vitrified-warmed blastocyst transfer (BT) cycles...
  88. ncbi Can 200 IU of hCG replace recombinant FSH in the late follicular phase in a GnRH-antagonist cycle? A pilot study
    C Blockeel
    Centre for Reproductive Medicine, UZ Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Hum Reprod 24:2910-6. 2009
    ..This randomised controlled trial (RCT) further explored whether low-dose hCG can be used clinically to replace recombinant FSH (rFSH) during the late follicular phase in a GnRH-antagonist protocol...
  89. ncbi Development of a national genetic evaluation for cow fertility
    P M Vanraden
    Animal Improvement Programs Laboratory, Agricultural Research Service, USDA, Beltsville, MD 20705 2350, USA paul aipl arsusda gov
    J Dairy Sci 87:2285-92. 2004
    A national fertility evaluation was developed based on pregnancy rate, which measures the percentage of nonpregnant cows becoming pregnant within each 21-d opportunity period...
  90. pmc Single-embryo transfer reduces clinical pregnancy rates and live births in fresh IVF and Intracytoplasmic Sperm Injection (ICSI) cycles: a meta-analysis
    Ricardo L R Baruffi
    Center for Human Reproduction, Sao Paolo, Brazil
    Reprod Biol Endocrinol 7:36. 2009
    ..This meta-analysis aimed to compare current data on single-embryo versus double-embryo transfer in fresh IVF/ICSI cycles with respect to implantation, ongoing pregnancy and live birth rates...
  91. ncbi Embryo and uterine influences on IVF outcomes: an analysis of a UK multi-centre cohort
    S A Roberts
    Health Sciences Methodology, Manchester Academic Health Science Centre MAHSC, University of Manchester, Manchester, UK
    Hum Reprod 25:2792-802. 2010
    ..Here, we develop a model to allow such prediction, and the structure of the models point to more general conclusions about the mode of action of prognostic factors...
  92. ncbi Low-dose HCG may improve pregnancy rates and lower OHSS in antagonist cycles: a meta-analysis
    I P Kosmas
    Centre for Reproductive Medicine, Department of Obstetrics and Gynecology, Ioannina University School of Medicine, Ioannina, Greece
    Reprod Biomed Online 19:619-30. 2009
    ..studies, in the gonadotrophin-releasing hormone antagonist group, a trend for significance in clinical pregnancy rate was evident (odds ratio [OR], 1.54; 95% confidence interval [CI], 0.98-2.42)...
  93. ncbi Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology
    Hassan W Bakos
    Discipline of Obstetrics and Gynaecology, School of Paediatrics and Reproductive Health, Robinson Institute, University of Adelaide, Adelaide, Australia
    Fertil Steril 95:1700-4. 2011
    ..To determine the relationship between paternal body mass index (BMI), embryo development and pregnancy, and live birth outcomes after assisted reproductive technology (ART)...
  94. ncbi Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients
    William B Schoolcraft
    Colorado Center for Reproductive Medicine, Lone Tree, CO 80124, USA
    Fertil Steril 96:638-40. 2011
    ....
  95. ncbi Impact of luteinizing hormone administration on gonadotropin-releasing hormone antagonist cycles: an age-adjusted analysis
    Ernesto Bosch
    Instituto Valenciano de Infertilidad, Valencia, Spain
    Fertil Steril 95:1031-6. 2011
    ..To analyze the impact of LH administration on cycle outcome in ovarian stimulation with GnRH antagonists...
  96. ncbi Impact of recombinant FSH dose adjustments on ovarian response in the second treatment cycle with IVF or ICSI in "standard" patients treated with 150 IU/day during the first cycle
    B Popovic-Todorovic
    The Fertility Clinic, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Acta Obstet Gynecol Scand 83:842-9. 2004
    ..In the second cycle, the starting dose is adjusted in those patients who had an inappropriate response during the first cycle. The purpose of the study was to assess the impact of dose adjustments on ovarian response...
  97. ncbi The effect of an individualized GnRH antagonist protocol on folliculogenesis in IVF/ICSI
    M H Mochtar
    Hum Reprod 19:1713-8. 2004
    ..The aim of this study was to assess the effect of an individualized GnRH antagonist regimen on folliculogenesis...
  98. ncbi Mastitis and fertility in cattle - possible involvement of inflammation or immune activation in embryonic mortality
    Peter J Hansen
    Department of Animal Sciences, University of Florida, Gainesville, FL, USA
    Am J Reprod Immunol 51:294-301. 2004
    ..Infection of the mammary gland in dairy cattle is associated with a reduction in pregnancy rate (proportion of inseminated cows that become pregnant) and an increase in the number of inseminations required ..
  99. ncbi Comparison of two different starting multiple dose gonadotropin-releasing hormone antagonist protocols in a selected group of in vitro fertilization-embryo transfer patients
    Ernesto Escudero
    Instituto Valenciano de Infertilidad, Valencia, Spain
    Fertil Steril 81:562-6. 2004
    ..To compare the efficacy of two starting protocols of multiple dose GnRH antagonists (GnRH-a)...
  100. ncbi Vaginal progesterone gel for luteal phase support in IVF/ICSI cycles: a meta-analysis
    Nikolaos P Polyzos
    Department of Obstetrics and Gynecology, University Hospital of Larissa, University of Thessalia, Larissa, Greece
    Fertil Steril 94:2083-7. 2010
    ..To investigate whether vaginal progesterone gel may result in similar or higher pregnancy rates compared with all other vaginal progesterone forms when used for luteal-phase support...
  101. pmc Use of the natural cycle and vitrification thawed blastocyst transfer results in better in-vitro fertilization outcomes : cycle regimens of vitrification thawed blastocyst transfer
    Eun Mi Chang
    Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650 9 Yeoksam, Kangnamgu, Seoul, 135 081, Korea
    J Assist Reprod Genet 28:369-74. 2011
    ..To compare the IVF outcomes of vitrification-thawed blastocyst transfer cycles utilizing different endometrial preparation methods...

Research Grants63

  1. Outcomes of Infertility Treatments in Clinic and Population-Based Cohorts
    Joseph B Stanford; Fiscal Year: 2010
    ..The results of this study will describe clinically relevant outcomes for couples seeking to have healthy children and will also inform the development of future targeted randomized trials. ..
  2. Validation of Novel Infertility Biomarker
    PETER SUTOVSKY SUTOVSKY; Fiscal Year: 2012
    ..Annually, more than 135,000 infertile couples are treated for infertility in US clinics, where the treatment-decision making still relies on outdated, highly subjective light microscopic method of semen evaluation. ..
  3. Functional Analysis of the Embryonic Epigenome in a Non-rodent Model
    Mark E Westhusin; Fiscal Year: 2013
    ....
  4. Molecular Analysis of GnRH Action
    Mark S Roberson; Fiscal Year: 2012
    ..Moreover, these studies will define the in vivo impact of genetic loss of key GnRH-regulated signaling molecules on fertility. ..
  5. Treatment of Hyperandrogenism vs. Insulin Resistance in Infertile PCOS Women
    Richard S Legro; Fiscal Year: 2012
    ..Our goal is to develop safe and effective treatments to improve the treatment of infertility in women with PCOS, but the findings can be generalized to all women with PCOS. ..
  6. Using Mixed Reality to build peer resistance skills in Latina middle schoolers
    ANNE E contact NORRIS; Fiscal Year: 2010
    ..Latinas are part of one of the fastest growing minority groups in the US and currently have a pregnancy rate that is nearly double that of non-Hispanic whites...
  7. Luteal Progesterone Supplementation in Clomiphene Citrate-IUI Cycles
    KARL RICHARD HANSEN; Fiscal Year: 2013
    ..The proposed investigation will determine whether supplemental progesterone improves pregnancy rates in women with unexplained infertility that undergo commonly utilized fertility treatments. ..
  8. GLUTS AND GLUCOSE TRANSPORT IN THE MOUSE BLASTOCYST
    Kelle H Moley; Fiscal Year: 2012
    ..By modulating the rate of autophagy during the preimplantation period in these models and then transferring these embryos into surrogate mice, the outcomes of these manipulations are determined. ..
  9. ACES: Abstinence and Contraception Education Storehouse
    JOSEFINA JAYME CARD; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Although the U.S. teen pregnancy rate has declined significantly over the last decade, it remains higher than that of many other industrialized countries and U.S...
  10. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    Christos Coutifaris; Fiscal Year: 2013
    ..The proposed clinical trial aims at markedly decreasing this undesired outcome taking advantage of recent advances that have resulted in embryos of high implantation potential...
  11. Chromium VI-induced toxicity on Female Reproductive Function
    SAKHILA BANU; Fiscal Year: 2012
    ..induce apoptosis of granulosa cells and follicular atresia, decrease oocyte quality, decrease ovulation and pregnancy rate, and induce preterm labor;and (ii) vitamin C will mitigate CrVI toxicity and protect the reproductive health ..
  12. Yo Puedo: Future Opportunities for Youth
    Alexandra M Minnis; Fiscal Year: 2011
    ..The study findings will guide design of a future Phase 3 effectiveness evaluation of this intervention. ..
  13. Role of Brg1 in Embryo Development and Pluripotency
    JASON GLENN KNOTT; Fiscal Year: 2013
    ..Collectively, these studies are highly relevant to the mission of the NICHD. ..
  14. Measuring and Explaining Unintended Pregnancy in the United States, 1987-2009
    Lawrence B Finer; Fiscal Year: 2013
    ..by incomplete information about its incidence, by inadequate understanding of the factors driving unintended pregnancy rate trends and differences across sociodemographic groups, and by lack of easy-to-use tools for regular monitoring ..
  15. Embryotropic actions of follistatin: mechanisms and translational relevance
    George W Smith; Fiscal Year: 2013
    ....
  16. Competing Priorities: Pregnancy and Disease Prevention among Young Adults
    SANDY MARIE HARVEY; Fiscal Year: 2013
    ..Findings will inform the design of clinical counseling and other programs to increase dual protection and prevent the acquisition/transmission of HIV/STIs and unintended pregnancy in this vulnerable population. ..
  17. Improving long-acting reversible contraception access for adolescents
    SUSAN ELIZABETH RUBIN; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Poor contraception adherence contributes to the U.S. adolescent pregnancy rate being among the highest in the industrialized world...
  18. Adolescent Latino Sexual Behavior: More Reactive or Reasoned?
    FELISA GONZALES; Fiscal Year: 2012
    ..The applicant is firmly committed to a research career that will contribute to the understanding and reduction of high STI, HIV, and unintended pregnancy rates among Latino adolescents. ..
  19. Race, contraceptive behavior, and unintended pregnancy
    Sonya B Borrero; Fiscal Year: 2013
    ....
  20. EC Method: Determinants for Copper IUD Use and Future Unintended Pregnancy
    David Turok; Fiscal Year: 2011
    ..This project will help family planning clinics meet the long term contraceptive needs of women presenting for emergency contraception and prevent unplanned pregnancies in this high risk group. ..
  21. Contraceptive Decision-Making: Women's Preferences for IUD-related Health States
    Bryna J Harwood; Fiscal Year: 2012
    ..it an appropriate method to investigate interventions to increase use and thereby decrease the unintended pregnancy rate. Increasing the use of highly effective methods such as the IUD will reduce the prevalence of unintended ..
  22. Adolescent Sex, Well-Being, and Normative Contexts
    Ann M Meier; Fiscal Year: 2013
    ..Adolescent sexual intercourse has clear and direct links to several aspects of physical health: the U.S. teen pregnancy rate is 71 (per 1000 girls 15-19), the teen birth rate is 42, and recent estimates indicate that one in four teen ..
  23. Improving Contraceptive Use in High-Risk Women
    TINA RENEE RAINE-BENNETT; Fiscal Year: 2013
    ..It is important to mentor the next generation of obstetricians and gynecologist trained in epidemiologic research and clinical trials methodology. ..
  24. A preclinical assessment of monthly intramuscular GSK1265744, an InSTI, as PrEP
    MARTIN H MARKOWITZ; Fiscal Year: 2013
    ....
  25. School-based Health Clinics: Effects on Youth and Young Adult Sexual Behavior
    Melina Bersamin; Fiscal Year: 2013
    ..Additionally, results will provide important data that can be used in efforts to help better understand how access to medical services more generally influences health behaviors. ..
  26. Effect of Continuous vs. Sequential Oral Contraception
    RICHARD LEGRO; Fiscal Year: 2004
    ..Therefore, the risks and benefits of a CCOCP regimen are an important women's health issue that warrant investigation. ..
  27. Urban American Indian Adolescent Female Sexual Risk Behavior
    MELISSA ANN SAFTNER; Fiscal Year: 2011
    ..These processes and factors will be examined with regards to sexual risk behavior and the unique culture that urban American Indians live within. ..
  28. Comprehensive aneuploidy diagnosis in single cells
    Nury Steuerwald; Fiscal Year: 2005
    ..The detection and avoidance of all aneuploid oocytes will lead to improved IVF outcomes for thousands of patients. Multiple births might also be reduced a s increased IVF success rates mean that fewer embryos need be transferred. ..
  29. Adolescent Perceptions of Risk in Research Participation
    C Lynn Sorsoli; Fiscal Year: 2010
    ..The study will offer empirical directions on how to design research studies optimizing protections for adolescent participants. ..
  30. Improved Implantation and Pregnancy Using Microfluidic Embryo Culture
    Xiaoyue Zhu; Fiscal Year: 2007
    ..This project will advance current technologies that provide near physiologic conditions to improve the developmental rate and cell formation for early stage embryos. [unreadable] [unreadable] [unreadable]..
  31. OXIDATIVE DAMAGE TO CRYOPRESERVED SPERM
    BAYARD STOREY; Fiscal Year: 1992
    ..The results of the proposed research are expected to form a completely new approach to the development of cryopreservation procedures for human sperm...
  32. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004
    ..We will also assess dual method use for STD prevention in the study to adoption of and adherence to oral contraceptives. We will also assess dual method use for STD prevention in the study population. ..
  33. CONVENTIONAL INFERTILITY THERAPY VS FAST TRACK TO IVF
    Richard Reindollar; Fiscal Year: 2004
    ..2) Because insurance coverage for infertility is required by Massachusetts law for all participants, the choice of therapeutic alternatives is not affected by the patients' ability to pay for treatment. ..
  34. A RCT of LNG-IUD vs. DMPA for young postpartum women
    Nancy Stanwood; Fiscal Year: 2005
    The U.S. has the highest unintended pregnancy rate of any developed country, mostly in teens and women in their early twenties due to ineffective contraceptive use...
  35. NORPLANT USE BY LOW-INCOME WOMEN
    Leslie Clarke; Fiscal Year: 1993
    ..This study responds to the need for research on new contraceptive methods and the need for reductions in unintended pregnancies in the U.S. as set forth in Healthy People 2000. ..
  36. RMU--EVALUATION OF TREATMENTS OF MALE FACTOR INFERTILITY
    Luigi Mastroianni; Fiscal Year: 1990
    ..Since they differ in cost and risk, this information will be most useful in establishing standards of care in the treatment of male factor infertility...
  37. Understanding unintended pregnancy among New Latinas: A mixed method approach.
    Anna Christensen; Fiscal Year: 2009
    ....
  38. CONTRACEPTION WITH MINI DOSE ANTIPROGESTIN IN MACAQUES
    MARY ZELINSKI WOOTEN; Fiscal Year: 2001
    ....
  39. ACES: Abstinence and Contraception Education Storehouse
    JOSEFINA CARD; Fiscal Year: 2006
    ..An estimated half of all new HIV infections in the U.S. occur in people under age 25. Further, the U.S. teen pregnancy rate remains significantly higher than that of other industrialized countries, and its unintended-pregnancy and ..
  40. DEPO PROVERA AND BONE MINERAL DENSITY IN ADOLESCENTS
    Barbara Cromer; Fiscal Year: 2003
    ..The statistical analysis will estimate the effect of DMPA on bone density while taking account of constant treatment discontinuation throughout the study period. ..
  41. Development of Superactive Analogs of Follice Stimulating Hormone (FSH)
    Bruce Weintraub; Fiscal Year: 2007
    ..In addition we plan to characterize selected purified analogs by multiple physicochemical methods relating to both protein and carbohydrate structure. [unreadable] [unreadable]..
  42. HIV DYNAMICS AND PREVENTION, RAKAI DISTRICT UGANDA
    Maria Wawer; Fiscal Year: 1992
    ..Women aged 20 to 24 had the highest prevalence (52%). The pregnancy rate among HIV positive and HIV negative was 12%...
  43. A NOVEL ORAL CONTRACEPTIVE INITIATION METHOD
    Patricia Murphy; Fiscal Year: 2000
    ..These data will then be used to estimate sample size, power and budget for the larger randomized trial to follow. ..
  44. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    David Guzick; Fiscal Year: 1990
    ....
  45. HIV PREVENTION FOR ADOLESCENT MOTHERS
    Deborah Koniak Griffin; Fiscal Year: 1999
    ....
  46. DEVELOPMENT OF A COORDINATED CERVICAL CAP SYSTEM
    JAMES KOCH; Fiscal Year: 1992
    ..available prefabricated cervical caps are ill fitting, are easily dislodged and provide an unacceptably high pregnancy rate. Experience, to date, suggests that a custom fitted cap might provide a means of long-term wear without ..
  47. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    Alan DeCherney; Fiscal Year: 1990
    ..order to establish normative data for pregnancy rates, and to assess the effect of clomiphene treatment on the pregnancy rate. The experimental protocol is constructed upon the randomized, double-blind crossover model...
  48. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    Alan DeCherney; Fiscal Year: 1991
    ..order to establish normative data for pregnancy rates, and to assess the effect of clomiphene treatment on the pregnancy rate. The experimental protocol is constructed upon the randomized, double-blind crossover model...
  49. PROCESSING CRYOPRESERVED HUMAN SPERM
    RUPERT AMANN; Fiscal Year: 2002
    ..from many/most patients (donors are highly selected) is unacceptable, 40 percent of the sperm are damaged, and pregnancy rate is low...
  50. A Dynamic Model of Teen Sex, Abortion and Childbearing
    Ahmed Khwaja; Fiscal Year: 2005
    ..The dynamic model will then be used to forecast both short and long run teen pregnancy and birth rates under different state policies regarding sex education, and access to reproductive health services. ..
  51. POLICY CHANGE EFFECTS ON PREGNANCY OUTCOMES
    ALLAN PARNELL; Fiscal Year: 2001
    ..Some of these outcomes are analyzed for socio-economic subgroups that are most extensively affected by changes in policies. ..
  52. PHI-443: Novel Non-Spermicidal Anti-HIV Microbicide
    OSMOND D CRUZ; Fiscal Year: 2003
    ..Specific Aims 1 and 2 may provide the foundation for the clinical development of PHI-443 in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
  53. PHI 346: A Novel Dual-Function Microbicide
    OSMOND D CRUZ; Fiscal Year: 2003
    ..Following successful completion of the Phase I in vivo efficacy studies, gel formulation of PHI-346 will be further explored as a vaginal dual-function microbicide in Phase II. ..
  54. METVAN: A Novel Anticancer Agent
    OSMOND D CRUZ; Fiscal Year: 2003
    ..The knowledge gained from these studies described under Specific Aims 1-2 is expected to facilitate the design of innovative treatment regimens employing METVAN for metastatic breast cancer and brain tumor patients. ..
  55. Increased Access to Emergency Contraceptive Pills
    Elizabeth Raymond; Fiscal Year: 2004
    ..These secondary analyses should help explain the primary biologic outcomes and should be useful in the development of counseling messages and service protocols in the future. ..
  56. Stampidine: A Novel Broad-Spectrum Anti-HIV Microbicide
    OSMOND D CRUZ; Fiscal Year: 2005
    ..Specific Aims 1 and 2 may provide the foundation for the clinical development of STAMP in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
  57. Phase II SBIR: WHI-07: A Novel Dual-Function Microbicide
    OSMOND D CRUZ; Fiscal Year: 2005
    ....
  58. FLP-102: Rationally Engineered Antiviral Protein
    OSMOND D CRUZ; Fiscal Year: 2003
    ..The preclinical data on FLP-102 will be essential to further explore the utility of this novel recombinant PAP mutant for Phase II. ..
  59. NOVEL CONTRACEPTIVES WITH ANTI-HIV ACTIVITY
    OSMOND D CRUZ; Fiscal Year: 2001
    ..The preclinical data on in vivo efficacies of WHI-05 and WHI-07 will be essential to further explore the utility of these novel drugs for clinical studies in human patients. ..
  60. Vanadocenes as a New Class of Spermicidal Drugs
    OSMOND D CRUZ; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  61. Full karyotype single cell interphase analysis
    Santiago Munne; Fiscal Year: 2005
    ..In phase-I we propose to develop two of the three sets of probes, and to test that these probes will work with 90% efficiency after three rounds of hybridization in single polar bodies. ..
  62. Supporting Human ART Through Basic Science
    Barry Bavister; Fiscal Year: 2004
    ..This Symposium will attract members of the human ART community and scientists working in animal ART, and will provide a basis for continued and expanded interactions between these two groups. ..
  63. MARKER ASSISTED SELECTION OF BOVINE BLASTOCYSTS
    HANS KUBISCH; Fiscal Year: 2002
    ....