infant mortality

Summary

Summary: Postneonatal deaths between 28 days and 365 days after BIRTH in a given population (as defined by National Center for Health Statistics). Perinatal mortality represents deaths from 28th week of GESTATION to 7th day after birth. Neonatal mortality represents deaths from birth to 27 days after birth.

Top Publications

  1. ncbi Where and why are 10 million children dying every year?
    Robert E Black
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 361:2226-34. 2003
  2. ncbi Effect of a participatory intervention with women's groups on birth outcomes in Nepal: cluster-randomised controlled trial
    Dharma S Manandhar
    Mother and Infant Research Activities MIRA, PO Box 921, Kathmandu, Nepal
    Lancet 364:970-9. 2004
  3. ncbi 4 million neonatal deaths: when? Where? Why?
    Joy E Lawn
    Saving Newborn Lives Save the Children USA, and International Perinatal Care Unit, Institute of Child Health, London, Cape Town, South Africa
    Lancet 365:891-900. 2005
  4. doi Causes of deaths in children younger than 5 years in China in 2008
    Igor Rudan
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Lancet 375:1083-9. 2010
  5. doi Progress towards Millennium Development Goals 4 and 5 on maternal and child mortality: an updated systematic analysis
    Rafael Lozano
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA
    Lancet 378:1139-65. 2011
  6. ncbi Evidence-based, cost-effective interventions: how many newborn babies can we save?
    Gary L Darmstadt
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Lancet 365:977-88. 2005
  7. doi Countdown to 2015 decade report (2000-10): taking stock of maternal, newborn, and child survival
    Zulfiqar A Bhutta
    Aga Khan University, Karachi, Pakistan
    Lancet 375:2032-44. 2010
  8. pmc Neonatal mortality levels for 193 countries in 2009 with trends since 1990: a systematic analysis of progress, projections, and priorities
    Mikkel Zahle Oestergaard
    World Health Organization, Department of Health statistics and informatics, Geneva, Switzerland
    PLoS Med 8:e1001080. 2011
  9. doi An overview of mortality and sequelae of preterm birth from infancy to adulthood
    Saroj Saigal
    Department of Paediatrics, McMaster University, Hamilton, ON, Canada
    Lancet 371:261-9. 2008
  10. doi Neonatal, postneonatal, childhood, and under-5 mortality for 187 countries, 1970-2010: a systematic analysis of progress towards Millennium Development Goal 4
    JULIE KNOLL RAJARATNAM
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA
    Lancet 375:1988-2008. 2010

Detail Information

Publications342 found, 100 shown here

  1. ncbi Where and why are 10 million children dying every year?
    Robert E Black
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 361:2226-34. 2003
    ..A better understanding of child health epidemiology could contribute to more effective approaches to saving children's lives...
  2. ncbi Effect of a participatory intervention with women's groups on birth outcomes in Nepal: cluster-randomised controlled trial
    Dharma S Manandhar
    Mother and Infant Research Activities MIRA, PO Box 921, Kathmandu, Nepal
    Lancet 364:970-9. 2004
    ..90% of deliveries in the poorest quintile of households happen at home. We postulated that a community-based participatory intervention could significantly reduce neonatal mortality rates...
  3. ncbi 4 million neonatal deaths: when? Where? Why?
    Joy E Lawn
    Saving Newborn Lives Save the Children USA, and International Perinatal Care Unit, Institute of Child Health, London, Cape Town, South Africa
    Lancet 365:891-900. 2005
    ..While we neglect these challenges, 450 newborn children die every hour, mainly from preventable causes, which is unconscionable in the 21st century...
  4. doi Causes of deaths in children younger than 5 years in China in 2008
    Igor Rudan
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Lancet 375:1083-9. 2010
    ..We identified the main causes of deaths in neonates (<1 month), postneonatal infants (1-11 months), and children (<5 years) in China using information that was available to the public...
  5. doi Progress towards Millennium Development Goals 4 and 5 on maternal and child mortality: an updated systematic analysis
    Rafael Lozano
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA
    Lancet 378:1139-65. 2011
    ..Our aim was to update previous estimates of maternal and child mortality using better data and more robust methods to provide the best available evidence for tracking progress on MDGs 4 and 5...
  6. ncbi Evidence-based, cost-effective interventions: how many newborn babies can we save?
    Gary L Darmstadt
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Lancet 365:977-88. 2005
    ..Simultaneous expansion of clinical care for babies and mothers is essential to achieve the reduction in neonatal deaths needed to meet the Millennium Development Goal for child survival...
  7. doi Countdown to 2015 decade report (2000-10): taking stock of maternal, newborn, and child survival
    Zulfiqar A Bhutta
    Aga Khan University, Karachi, Pakistan
    Lancet 375:2032-44. 2010
    ..However, much more can and should be done to address maternal and newborn health and improve coverage of interventions related to family planning, care around childbirth, and case management of childhood illnesses...
  8. pmc Neonatal mortality levels for 193 countries in 2009 with trends since 1990: a systematic analysis of progress, projections, and priorities
    Mikkel Zahle Oestergaard
    World Health Organization, Department of Health statistics and informatics, Geneva, Switzerland
    PLoS Med 8:e1001080. 2011
    ..To better assess progress, we developed annual estimates for neonatal mortality rates (NMRs) and neonatal deaths for 193 countries for the period 1990-2009 with forecasts into the future...
  9. doi An overview of mortality and sequelae of preterm birth from infancy to adulthood
    Saroj Saigal
    Department of Paediatrics, McMaster University, Hamilton, ON, Canada
    Lancet 371:261-9. 2008
    ..In addition, follow-up to middle age and beyond is warranted to identify the risks, especially for cardiovascular and metabolic disorders that are likely to be experienced by preterm survivors...
  10. doi Neonatal, postneonatal, childhood, and under-5 mortality for 187 countries, 1970-2010: a systematic analysis of progress towards Millennium Development Goal 4
    JULIE KNOLL RAJARATNAM
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA
    Lancet 375:1988-2008. 2010
    ..In view of policy initiatives and investments made since 2000, it is important to see if there is acceleration towards the MDG 4 target. We assessed levels and trends in child mortality for 187 countries from 1970 to 2010...
  11. doi Effect of community-based newborn-care intervention package implemented through two service-delivery strategies in Sylhet district, Bangladesh: a cluster-randomised controlled trial
    Abdullah H Baqui
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 371:1936-44. 2008
    ..Therefore the project for advancing the health of newborns and mothers (Projahnmo) implemented a community-based intervention package through government and non-government organisation infrastructures to reduce neonatal mortality...
  12. ncbi How many child deaths can we prevent this year?
    Gareth Jones
    Division of Policy and Planning, United Nations Children s Fund, New York, NY 10017, USA
    Lancet 362:65-71. 2003
    ....
  13. doi Effects of prenatal micronutrient and early food supplementation on maternal hemoglobin, birth weight, and infant mortality among children in Bangladesh: the MINIMat randomized trial
    Lars Ake Persson
    Department of Women s and Children s Health, International Maternal and Child Health, Uppsala University, Uppsala, Sweden
    JAMA 307:2050-9. 2012
    ..Nutritional insult in fetal life and small size at birth are common in low-income countries and are associated with serious health consequences...
  14. doi Effect of a participatory intervention with women's groups on birth outcomes and maternal depression in Jharkhand and Orissa, India: a cluster-randomised controlled trial
    Prasanta Tripathy
    Ekjut, Chakradharpur, Jharkhand, India
    Lancet 375:1182-92. 2010
    ..Community mobilisation through participatory women's groups might improve birth outcomes in poor rural communities. We therefore assessed this approach in a largely tribal and rural population in three districts in eastern India...
  15. ncbi Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis
    Marie Louise Newell
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, UK
    Lancet 364:1236-43. 2004
    ..With individual data from seven randomised mother-to-child transmission (MTCT) intervention trials, we estimate mortality in African children born to HIV-infected mothers and analyse selected risk factors...
  16. ncbi Continuum of care for maternal, newborn, and child health: from slogan to service delivery
    Kate J Kerber
    Saving Newborn Lives, Save the Children, Washington, DC, USA
    Lancet 370:1358-69. 2007
    ....
  17. doi Effect of community-based behaviour change management on neonatal mortality in Shivgarh, Uttar Pradesh, India: a cluster-randomised controlled trial
    Vishwajeet Kumar
    International Center for Advancing Neonatal Health, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Lancet 372:1151-62. 2008
    ..We developed an intervention of behaviour change management, with a focus on prevention of hypothermia, aimed at modifying practices and reducing neonatal mortality...
  18. ncbi Maternal health in poor countries: the broader context and a call for action
    Veronique Filippi
    Maternal and Neonatal Health Group, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Lancet 368:1535-41. 2006
    ..Finally, after examining the political and financial context, we call for action. The need for strategic vision, financial resources, human resources, and information are discussed...
  19. ncbi Rates of caesarean section: analysis of global, regional and national estimates
    Ana P Betrán
    Department of Making Pregnancy Safer, World Health Organisation, Geneva, Switzerland
    Paediatr Perinat Epidemiol 21:98-113. 2007
    ..There is some suggestion of a direct positive association at lower levels of mortality. CS levels may respond primarily to economic determinants...
  20. ncbi Applying an equity lens to child health and mortality: more of the same is not enough
    Cesar G Victora
    Universidade Federal de Pelotas, Pelotas, Brazil
    Lancet 362:233-41. 2003
    ..Equity must be a priority in the design of child survival interventions and delivery strategies, and mechanisms to ensure accountability at national and international levels must be developed...
  21. ncbi Caesarean delivery rates and pregnancy outcomes: the 2005 WHO global survey on maternal and perinatal health in Latin America
    Jose Villar
    UNDP UNFPA WHO World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, WHO, 1211 Geneva 27, Switzerland
    Lancet 367:1819-29. 2006
    ..Our aim was to assess the association between caesarean delivery and pregnancy outcome at the institutional level, adjusting for the pregnant population and institutional characteristics...
  22. doi Effect of scaling up women's groups on birth outcomes in three rural districts in Bangladesh: a cluster-randomised controlled trial
    Kishwar Azad
    Perinatal Care Project, Diabetic Association of Bangladesh, Shahbagh, Dhaka, Bangladesh
    Lancet 375:1193-202. 2010
    ..We assessed the effectiveness of a scaled-up development programme with women's groups to address maternal and neonatal care in three rural districts of Bangladesh...
  23. doi Newborn survival: a multi-country analysis of a decade of change
    Joy E Lawn
    Save the Children, Cape Town, South Africa
    Health Policy Plan 27:iii6-28. 2012
    ..Accelerating progress requires data-driven investments and addressing context-specific implementation realities...
  24. ncbi On the importance--and the unimportance--of birthweight
    A J Wilcox
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham NC 27709, USA
    Int J Epidemiol 30:1233-41. 2001
    ..Under this assumption of causality, birthweight is used to explain variations in infant mortality and later morbidity, and is also used as an intermediate health endpoint in itself...
  25. doi Alma-Ata: Rebirth and Revision 6 Interventions to address maternal, newborn, and child survival: what difference can integrated primary health care strategies make?
    Zulfiqar A Bhutta
    Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan
    Lancet 372:972-89. 2008
    ..Strengthening MNCH at the primary health-care level should be a priority for countries to reach their Millennium Development Goal targets for reducing maternal and child mortality...
  26. doi 3.6 million neonatal deaths--what is progressing and what is not?
    Joy E Lawn
    Saving Newborn Lives Save the Children US, Cape Town, South Africa
    Semin Perinatol 34:371-86. 2010
    ..A critical step is improving the quantity, quality and use of data to select and implement the most effective interventions and strengthen existing programs, especially at district level...
  27. pmc Newborn-care training and perinatal mortality in developing countries
    Waldemar A Carlo
    University of Alabama at Birmingham, Birmingham, AL 35233, USA
    N Engl J Med 362:614-23. 2010
    ..Of the 3.7 million neonatal deaths and 3.3 million stillbirths each year, 98% occur in developing countries. An evaluation of community-based interventions designed to reduce the number of these deaths is needed...
  28. pmc Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data
    Joy E Lawn
    Saving Newborn Lives Save the Children, 11 South Way, Pinelands Cape Town, South Africa
    BMC Pregnancy Childbirth 10:S1. 2010
    ..This is the first of seven articles from a preterm birth and stillbirth report. Presented here is an overview of the burden, an assessment of the quality of current estimates, review of trends, and recommendations to improve data...
  29. doi Countdown to 2015 for maternal, newborn, and child survival: the 2008 report on tracking coverage of interventions
    Jennifer Bryce
    Johns Hopkins School of Public Health, USA
    Lancet 371:1247-58. 2008
    ..We aimed to report on 68 countries which have 97% of maternal and child deaths worldwide, and on 22 interventions that have been proven to improve maternal, newborn, and child survival...
  30. pmc Causes of neonatal and child mortality in India: a nationally representative mortality survey
    Diego G Bassani
    Centre for Global Health Research, Li Ka Shing Knowledge Institute, St Michael s Hospital and Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5B 1W8, Canada
    Lancet 376:1853-60. 2010
    ..More than 2·3 million children died in India in 2005; however, the major causes of death have not been measured in the country. We investigated the causes of neonatal and child mortality in India and their differences by sex and region...
  31. pmc Influence of definition based versus pragmatic birth registration on international comparisons of perinatal and infant mortality: population based retrospective study
    K S Joseph
    Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada V6H 3N1
    BMJ 344:e746. 2012
    To examine variations in the registration of extremely low birthweight and early gestation births and to assess their effect on perinatal and infant mortality rankings of industrialised countries.
  32. doi Topical application of chlorhexidine to neonatal umbilical cords for prevention of omphalitis and neonatal mortality in a rural district of Pakistan: a community-based, cluster-randomised trial
    Sajid Soofi
    Division of Women and Child Health, Aga Khan University, Karachi, Pakistan
    Lancet 379:1029-36. 2012
    ..We aimed to assess the effect of umbilical-cord cleansing with 4% chlorhexidine (CHX) solution, with or without handwashing with antiseptic soap, on the incidence of omphalitis and neonatal mortality...
  33. doi Nasal CPAP or intubation at birth for very preterm infants
    Colin J Morley
    Neonatal Services, Royal Women s Hospital, Melbourne, Australia
    N Engl J Med 358:700-8. 2008
    ....
  34. pmc A cluster randomised controlled trial of the community effectiveness of two interventions in rural Malawi to improve health care and to reduce maternal, newborn and infant mortality
    Sonia Lewycka
    Centre for International Health and Development, UCL Institute of Child Health, London, UK
    Trials 11:88. 2010
    ..The MaiMwana Project aims to test community-based interventions that tackle maternal and child health problems through increasing awareness and local action...
  35. pmc Effects of early, abrupt weaning on HIV-free survival of children in Zambia
    Louise Kuhn
    Gertrude H Sergievsky Center and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York 10032, USA
    N Engl J Med 359:130-41. 2008
    ..We conducted a randomized trial to evaluate whether abrupt weaning at 4 months as compared with the standard practice has a net benefit for HIV-free survival of children...
  36. pmc Determinants of neonatal mortality in Indonesia
    Christiana R Titaley
    School of Public Health, Edward Ford Building A27, University of Sydney, NSW 2006, Australia
    BMC Public Health 8:232. 2008
    ..This study aimed to identify the determinants of neonatal mortality in Indonesia, for a nationally representative sample of births from 1997 to 2002...
  37. ncbi The burden of malaria in pregnancy in malaria-endemic areas
    R W Steketee
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 64:28-35. 2001
    ..prematurity and intrauterine growth retardation (IUGR), fetal parasite exposure and congenital infection, and infant mortality (IM) linked to preterm-LBW and IUGR-LBW...
  38. pmc Impact of malaria at the end of pregnancy on infant mortality and morbidity
    Azucena Bardaji
    Barcelona Centre for International Health Research and Department of Pathology, Hospital Clinic, Institut d Investigacions Biomedicas August Pi i Sunyer, Universitat de Barcelona, Spain
    J Infect Dis 203:691-9. 2011
    ..There is some consensus that malaria in pregnancy may negatively affect infant's mortality and malaria morbidity, but there is less evidence concerning the factors involved...
  39. doi Newborn survival in low resource settings--are we delivering?
    J E Lawn
    Saving Newborn Lives Save the Children USA, Cape Town 7405, South Africa
    BJOG 116:49-59. 2009
    ..There are promising models that have been tested mainly in research studies in Asia that are now being adapted and evaluated at scale including through a network of African implementation research trials...
  40. pmc Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trial
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
    Lancet 367:910-8. 2006
    ..Omphalitis contributes to neonatal morbidity and mortality in developing countries. Umbilical cord cleansing with antiseptics might reduce infection and mortality risk, but has not been rigorously investigated...
  41. ncbi Effect of pneumonia case management on mortality in neonates, infants, and preschool children: a meta-analysis of community-based trials
    Sunil Sazawal
    Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet Infect Dis 3:547-56. 2003
    ..Community-based interventions to identify and treat pneumonia have a substantial effect on neonatal, infant, and child mortality and should be incorporated into primary health care...
  42. doi Preventing preterm birth and neonatal mortality: exploring the epidemiology, causes, and interventions
    Lavone E Simmons
    Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195 6460, USA
    Semin Perinatol 34:408-15. 2010
    ....
  43. pmc A prospective study on neonatal mortality and its predictors in a rural area in Burkina Faso: can MDG-4 be met by 2015?
    A H Diallo
    Centre MURAZ Research Institute, Ministry of Health Burkina Faso, Bobo Dioulasso, Burkina Faso
    J Perinatol 31:656-63. 2011
    ..To measure the neonatal mortality rate (NMR) and investigate its predictors in a rural area of Burkina Faso...
  44. pmc Effect of implementation of Integrated Management of Neonatal and Childhood Illness (IMNCI) programme on neonatal and infant mortality: cluster randomised controlled trial
    Nita Bhandari
    Centre for Health Research and Development, Society for Applied Studies, 45 Kalu Sarai, New Delhi 110016, India
    BMJ 344:e1634. 2012
    ..To evaluate the Indian Integrated Management of Neonatal and Childhood Illness (IMNCI) programme, which integrates improved treatment of illness for children with home visits for newborn care, to inform its scale-up...
  45. ncbi Effects of preceding birth intervals on neonatal, infant and under-five years mortality and nutritional status in developing countries: evidence from the demographic and health surveys
    S O Rutstein
    ORC Macro, 11785 Beltsville Drive, Calverton, MD 20705, USA
    Int J Gynaecol Obstet 89:S7-24. 2005
    ..This paper examines the association between birth intervals and infant and child mortality and nutritional status...
  46. doi Behavior change for newborn survival in resource-poor community settings: bridging the gap between evidence and impact
    Vishwajeet Kumar
    Habitat for Global Health, Shivgarh, Uttar Pradesh, India
    Semin Perinatol 34:446-61. 2010
    ..We finally touch upon key overarching principles that should guide intervention execution for maximal impact...
  47. doi Improvement of perinatal and newborn care in rural Pakistan through community-based strategies: a cluster-randomised effectiveness trial
    Zulfiqar A Bhutta
    Division of Women and Child Health, Aga Khan University, Karachi, Pakistan zulfi
    Lancet 377:403-12. 2011
    ....
  48. pmc Risk factors of infant and child mortality in rural Burkina Faso
    Heiko Becher
    University of Heidelberg, Department of Tropical Hygiene and Public Health, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
    Bull World Health Organ 82:265-73. 2004
    ..The aim of the study was to quantify the effect of risk factors for childhood mortality in a typical rural setting in sub-Saharan Africa...
  49. pmc No cry at birth: global estimates of intrapartum stillbirths and intrapartum-related neonatal deaths
    Joy Lawn
    Saving Newborn Lives Save the Children, International Perinatal Care Unit, Institute of Child Health, London, England
    Bull World Health Organ 83:409-17. 2005
    ..7 to 1.2 million. Estimates for intrapartum stillbirths are not available. We aimed to estimate the numbers of intrapartum-related neonatal deaths and intrapartum stillbirths in the year 2000...
  50. ncbi Decomposing socioeconomic inequality in infant mortality in Iran
    Ahmad Reza Hosseinpoor
    Department of Equity, Poverty and Social Determinants of Health, Evidence and Information for Policy, World Health Organization, Geneva, Switzerland
    Int J Epidemiol 35:1211-9. 2006
    Although measuring socioeconomic inequality in population health indicators like infant mortality is important, more interesting for policy purposes is to try to explain infant mortality inequality...
  51. ncbi Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study
    Ibou Thior
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 296:794-805. 2006
    ..Postnatal transmission of human immunodeficiency virus-1 (HIV) via breastfeeding reverses gains achieved by perinatal antiretroviral interventions...
  52. doi Stillbirths: how can health systems deliver for mothers and babies?
    Robert Pattinson
    Medical Research Council Maternal and Infant Health Care Strategies Research Unit, Department of Obstetrics and Gynaecology, University of Pretoria, Pretoria, South Africa
    Lancet 377:1610-23. 2011
    ....
  53. ncbi The perinatal effects of delayed childbearing
    K S Joseph
    Perinatal Epidemiology Research Unit, Departments of Obstetrics and Gynaecology and Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Obstet Gynecol 105:1410-8. 2005
    ....
  54. pmc 'Kangaroo mother care' to prevent neonatal deaths due to preterm birth complications
    Joy E Lawn
    Saving Newborn Lives Save the Children USA, Cape Town, South Africa
    Int J Epidemiol 39:i144-54. 2010
    ..Whilst increasingly accepted in both high- and low-income countries, a Cochrane review (2003) did not find evidence of KMC's mortality benefit, and did not report neonatal-specific data...
  55. ncbi Are some perinatal deaths in immigrant groups linked to suboptimal perinatal care services?
    Birgitta Essen
    Department of Obstetrics and Gynaecology, Malmo University Hospital, Lund University, Sweden
    BJOG 109:677-82. 2002
    ..To test the hypothesis that suboptimal factors in perinatal care services resulting in perinatal deaths were more common among immigrant mothers from the Horn of Africa, when compared with Swedish mothers...
  56. ncbi Trends in mortality and morbidity for very low birth weight infants, 1991-1999
    Jeffrey D Horbar
    University of Vermont Department of Pediatrics, Burlington, Vermont Vermont Oxford Network, Burlington, Vermont, USA
    Pediatrics 110:143-51. 2002
    ..Medical care for very low birth weight (VLBW) infants and their mothers has changed dramatically during the 1990s, yet it is unclear how these changes have affected mortality and morbidity...
  57. ncbi Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis
    Rebecca A Jackson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 505 Parnassus Avenue, Box 0132, San Francisco, CA 94143, USA
    Obstet Gynecol 103:551-63. 2004
    ....
  58. pmc Maternal and neonatal individual risks and benefits associated with caesarean delivery: multicentre prospective study
    Jose Villar
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford OX3 9DU
    BMJ 335:1025. 2007
    ..To assess the risks and benefits associated with caesarean delivery compared with vaginal delivery...
  59. doi How access to health care relates to under-five mortality in sub-Saharan Africa: systematic review
    Merrin E Rutherford
    Centre for International Health, University of Otago, Dunedin, New Zealand
    Trop Med Int Health 15:508-19. 2010
    ..Analytical studies that comprehensively evaluate both traditional and additional variables in developing countries are required...
  60. pmc Measuring under-five mortality: validation of new low-cost methods
    JULIE KNOLL RAJARATNAM
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America
    PLoS Med 7:e1000253. 2010
    ..As a result, there is a demand for improvement of the methods employing summary birth history data to produce more accurate as well as subnational estimates of child mortality...
  61. doi One-year survival of extremely preterm infants after active perinatal care in Sweden
    Vineta Fellman
    Department of Obstetrics and Gynecology, Lund University Hospital, S 221 85 Lund, Sweden
    JAMA 301:2225-33. 2009
    ..Up-to-date information on infant survival after extremely preterm birth is needed for assessing perinatal care services, clinical guidelines, and parental counseling...
  62. pmc Effect of training traditional birth attendants on neonatal mortality (Lufwanyama Neonatal Survival Project): randomised controlled study
    Christopher J Gill
    Center for Global Health and Development, Boston University, Boston, MA, USA
    BMJ 342:d346. 2011
    ..To determine whether training traditional birth attendants to manage several common perinatal conditions could reduce neonatal mortality in the setting of a resource poor country with limited access to healthcare...
  63. doi Arsenic exposure and risk of spontaneous abortion, stillbirth, and infant mortality
    Anisur Rahman
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Epidemiology 21:797-804. 2010
    ..We assessed the association of arsenic exposure with adverse pregnancy outcomes and infant mortality in a prospective cohort study of pregnant women.
  64. ncbi Neonatal survival: a call for action
    Jose Martines
    Department of Child and Adolescent Health and Development, WHO, Geneva, Switzerland
    Lancet 365:1189-97. 2005
    ..International donors and leaders of developing countries should be held accountable for meeting their commitments and increasing resources...
  65. pmc Neonatal mortality, risk factors and causes: a prospective population-based cohort study in urban Pakistan
    Imtiaz Jehan
    Aga Khan University, Karachi, Pakistan
    Bull World Health Organ 87:130-8. 2009
    ..To evaluate the prevalence, sex distribution and causes of neonatal mortality, as well as its risk factors, in an urban Pakistani population with access to obstetric and neonatal care...
  66. pmc Risk factors for early infant mortality in Sarlahi district, Nepal
    Joanne Katz
    Division of Disease Prevention and Control, Center for Human Nutrition, Sight and Life Research Institute, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Bull World Health Organ 81:717-25. 2003
    Early infant mortality has not declined as rapidly as child mortality in many countries. Identification of risk factors for early infant mortality may help inform the design of intervention strategies.
  67. pmc What explains the rural-urban gap in infant mortality: household or community characteristics?
    Ellen Van de Poel
    Erasmus School of Economics, Erasmus University Rotterdam, Burg Oudlaan 50, 3000 DR Rotterdam, The Netherlands
    Demography 46:827-50. 2009
    The rural-urban gap in infant mortality rates is explained by using a new decomposition method that permits identification of the contribution of unobserved heterogeneity at the household and the community level...
  68. doi The effect of distance to health-care facilities on childhood mortality in rural Burkina Faso
    Anja Schoeps
    Institute of Public Health, University of Heidelberg, Germany
    Am J Epidemiol 173:492-8. 2011
    ..The findings of this study emphasize the importance of geographic accessibility of health care for child survival in sub-Saharan Africa and demonstrate the need to improve health-care access to achieve the Millennium Development Goals...
  69. pmc Young and vulnerable: spatial-temporal trends and risk factors for infant mortality in rural South Africa (Agincourt), 1992-2007
    Benn K D Sartorius
    MRC Wits Rural Public Health and Health Transitions Research Unit, Agincourt, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    BMC Public Health 10:645. 2010
    b>Infant mortality is an important indicator of population health in a country...
  70. doi Term pregnancy: a period of heterogeneous risk for infant mortality
    Uma M Reddy
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
    Obstet Gynecol 117:1279-87. 2011
    ..To estimate the trend of maternal racial and ethnic differences in mortality for early-term (37 0/7 to 38 6/7 weeks of gestation) compared with full-term births (39 0/7 to 41 6/7 weeks of gestation)...
  71. ncbi Malaria in pregnancy as an indirect cause of infant mortality in sub-Saharan Africa
    H L Guyatt
    Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
    Trans R Soc Trop Med Hyg 95:569-76. 2001
    ..have demonstrated an increase in the birthweight of the newborn in primigravidae, the subsequent impact on infant mortality in all-parities has not been assessed...
  72. ncbi The contribution of mild and moderate preterm birth to infant mortality. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System
    M S Kramer
    1020 Pine Ave W, Montreal, Quebec, Canada H3A 1A2
    JAMA 284:843-9. 2000
    ..However, infants born at 32 through 36 weeks are more common and their public health impact has not been well studied...
  73. doi A comparison of four prenatal care indices in birth outcome models: comparable results for predicting small-for-gestational-age outcome but different results for preterm birth or infant mortality
    Tyler J VanderWeele
    University of Chicago, Department of Health Studies, Chicago, IL 60637, USA
    J Clin Epidemiol 62:438-45. 2009
    ..to analyze the relationship between the adequacy of prenatal care and low birthweight, preterm birth, and infant mortality. This investigation compared the performance of the Kessner index, the GINDEX, the adequacy of prenatal care ..
  74. pmc Factors associated with trends in infant and child mortality in developing countries during the 1990s
    S O Rutstein
    ORC Macro International, Inc, Calverton, MD 20705, USA
    Bull World Health Organ 78:1256-70. 2000
    ..Other factors that were not measured, such as the increasing resistance of malaria to drug treatment and the increased prevalence of parental HIV/AIDS, may be contributing to the increase noted...
  75. doi Welfare state regimes, infant mortality and life expectancy: integrating evidence from East Asia
    Ying Chih Chuang
    School of Public Health, Taipei Medical University, Taipei, Taiwan
    J Epidemiol Community Health 66:e23. 2012
    ....
  76. pmc Equity and geography: the case of child mortality in Papua New Guinea
    Anna E Bauze
    Burnet Institute, Melbourne, Victoria, Australia
    PLoS ONE 7:e37861. 2012
    ..This study aims to estimate under-five mortality in PNG at national and subnational levels to examine the importance of geographical inequities in health outcomes and track progress towards Millennium Development Goal (MDG) 4...
  77. pmc Causes of stillbirths and early neonatal deaths: data from 7993 pregnancies in six developing countries
    Nhu Thi Nguyen Ngoc
    Hung Vuong Hospital, 128 Hungvuong Street, 105 Ho Chi Minh City, Viet Nam
    Bull World Health Organ 84:699-705. 2006
    ....
  78. pmc The effect of changing patterns of obstetric care in Scotland (1980-2004) on rates of preterm birth and its neonatal consequences: perinatal database study
    Jane E Norman
    University of Edinburgh Centre for Reproductive Biology, Edinburgh, UK
    PLoS Med 6:e1000153. 2009
    ..We aimed, in a population-based database of 5 million people, to determine the temporal trends and obstetric antecedents of singleton preterm birth and its associated neonatal mortality and morbidity for the period 1980-2004...
  79. pmc Distance decay in delivery care utilisation associated with neonatal mortality. A case referent study in northern Vietnam
    Mats Målqvist
    International Maternal and Child Health IMCH, Department of Women s and Children s Health, Uppsala University, Uppsala, Sweden
    BMC Public Health 10:762. 2010
    ..This study examined the association between distance from the mother's home to the closest health facility and neonatal mortality, and investigated the influence of distance on patterns of perinatal health care utilisation...
  80. pmc QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali
    Alexandre Dumont
    Department of Obstetrics and Gynecology, Universite de Montreal, Canada
    Trials 10:85. 2009
    ..Secondary goals include evaluation of the relationships between effectiveness and resource availability, service organization, medical practices, and satisfaction among health personnel...
  81. pmc Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies
    Frans M Helmerhorst
    Department of Obstetrics, Gynaecology and Reproductive Medicine, Leiden University Medical Center, NL 2300 Leiden, Netherlands
    BMJ 328:261. 2004
    ..To compare the perinatal outcome of singleton and twin pregnancies between natural and assisted conceptions...
  82. pmc Care seeking at time of childbirth, and maternal and perinatal mortality in Matlab, Bangladesh
    Carine Ronsmans
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, England
    Bull World Health Organ 88:289-96. 2010
    ..To examine the nature of the relationship between the use of skilled attendance around the time of delivery and maternal and perinatal mortality...
  83. ncbi Estimating the causes of 4 million neonatal deaths in the year 2000
    Joy E Lawn
    Saving Newborn Lives Save the Children USA, 11 South Way, Pinelands, Cape Town 7405, South Africa
    Int J Epidemiol 35:706-18. 2006
    ....
  84. pmc The effect of maternal child marriage on morbidity and mortality of children under 5 in India: cross sectional study of a nationally representative sample
    Anita Raj
    Boston University of Public Health, Department of Social and Behavioral Sciences, Boston, MA 02118, USA
    BMJ 340:b4258. 2010
    ..Data about child morbidity and mortality reported by participants. Analyses restricted to births in past five years reported by ever married women aged 15-24 years (n=19 302 births to 13 396 mothers)...
  85. ncbi Social determinants for infant mortality in the Nordic countries, 1980-2001
    Annett Arntzen
    Faculty of Social Science, Vestfold University College, Tønsberg, Norway
    Scand J Public Health 32:381-9. 2004
    Social equity in health is an important goal of public health policies in the Nordic countries. Infant mortality is often used as an indicator of the health of societies, and has decreased substantially in the Nordic welfare states over ..
  86. pmc Transition to skilled birth attendance: is there a future role for trained traditional birth attendants?
    Lynn M Sibley
    Center for Research on Maternal and Newborn Survival, Emory University, 1520 Clifton Road, Suite 436, Atlanta, GA 30322, USA
    J Health Popul Nutr 24:472-8. 2006
    ....
  87. pmc Cost effectiveness analysis of strategies for maternal and neonatal health in developing countries
    Taghreed Adam
    Health Systems Financing, Evidence and Information for Policy, World Health Organization, Switzerland
    BMJ 331:1107. 2005
    ..To determine the costs and benefits of interventions for maternal and newborn health to assess the appropriateness of current strategies and guide future plans to attain the millennium development goals...
  88. ncbi An intervention involving traditional birth attendants and perinatal and maternal mortality in Pakistan
    Abdul Hakeem Jokhio
    Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan
    N Engl J Med 352:2091-9. 2005
    ..There are approximately 4 million neonatal deaths and half a million maternal deaths worldwide each year. There is limited evidence from clinical trials to guide the development of effective maternity services in developing countries...
  89. ncbi Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland
    Claire L Townsend
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK
    AIDS 21:1019-26. 2007
    ..To explore the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005...
  90. doi Persistent neonatal mortality despite improved under-five survival: a retrospective cohort study in northern Vietnam
    Dinh P Hoa
    Department of Reproductive Health, Ministry of Health, Hanoi, Vietnam
    Acta Paediatr 97:166-70. 2008
    ..To examine trends in neonatal, infant and under-five mortality rates in a northern Vietnamese district during 1970-2000, and to analyze socioeconomic differences in child survival over time...
  91. ncbi Predictors of neonatal sepsis in developing countries
    Martin W Weber
    Medical Research Council Laboratories, Fajara, The Gambia
    Pediatr Infect Dis J 22:711-7. 2003
    ..Neonatal infections are a major cause of death worldwide. Simple procedures for identifying infants with infection that need referral for treatment are therefore of major public health importance...
  92. pmc Effect of 50,000 IU vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau: randomised placebo controlled trial
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    BMJ 336:1416-20. 2008
    To investigate the effect of high dose vitamin A supplementation given with BCG vaccine at birth in an African setting with high infant mortality.
  93. ncbi Pathways to infant mortality in urban slums of Delhi, India: implications for improving the quality of community- and hospital-based programmes
    Nita Bhandari
    Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
    J Health Popul Nutr 20:148-55. 2002
    ..into the processes underlying infant deaths to help identify preventive interventions which may bring down infant mortality rates further...
  94. doi Reduction in child mortality in Niger: a Countdown to 2015 country case study
    Agbessi Amouzou
    Institute for International Programs, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 380:1169-78. 2012
    ..Countdown therefore invited Niger to do an in-depth analysis of their child survival programme between 1998 and 2009...
  95. pmc Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths: a systematic review, meta-analysis and Delphi estimation of mortality effect
    Anne C C Lee
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    BMC Public Health 11:S12. 2011
    ..03 million from complications of prematurity. No systematic assessment of mortality reduction from tactile stimulation or resuscitation has been published...
  96. doi Stillbirths and early neonatal mortality in rural Northern Ghana
    Cyril Engmann
    Department of Pediatrics, University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, NC 27599 7596, USA
    Trop Med Int Health 17:272-82. 2012
    ....
  97. doi Emergency obstetric care availability: a critical assessment of the current indicator
    Sabine Gabrysch
    Institute of Public Health, Ruprecht Karls Universitat, Heidelberg, Germany
    Trop Med Int Health 17:2-8. 2012
    ....
  98. pmc Perinatal mortality in eastern Uganda: a community based prospective cohort study
    Victoria Nankabirwa
    Department of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda
    PLoS ONE 6:e19674. 2011
    ..We report stillbirth and early neonatal mortality risks as well as determinants of perinatal mortality in Eastern Uganda...
  99. pmc Infant and child mortality in India in the last two decades: a geospatial analysis
    Abhishek Singh
    Department of Public Health and Mortality Studies, International Institute for Population Sciences, Mumbai, Maharashtra, India
    PLoS ONE 6:e26856. 2011
    ....
  100. pmc Survival of neonates in rural Southern Tanzania: does place of delivery or continuum of care matter?
    Rose Nathan
    Ifakara Health Institute, Dar es Salaam, Ifakara, Tanzania
    BMC Pregnancy Childbirth 12:18. 2012
    ..This paper uses longitudinal data generated in a Health and Demographic Surveillance System in rural Southern Tanzania to assess associations of neonatal mortality and place of delivery...
  101. pmc Does air pollution trigger infant mortality in Western Europe? A case-crossover study
    Hans Scheers
    Department of Public Health, Occupational and Environmental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Environ Health Perspect 119:1017-22. 2011
    ..Numerous studies show associations between fine particulate air pollutants [particulate matter with an aerodynamic diameter ≤ 10 μm (PM₁₀)] and mortality in adults...

Research Grants78

  1. ORGANIZATION OF CENTRAL SYMPATHETIC PATHWAYS
    Patrice G Guyenet; Fiscal Year: 2013
    ..syndrome and is a probable mechanism of sudden infant death syndrome (SIDS), the main cause of infant mortality in industrialized countries (5 per thousand live births)...
  2. Polycyclic aromatic hydrocarbons and birth outcomes in Mexico City
    MARIE SYLVIA O'NEILL; Fiscal Year: 2013
    ..Reducing infant mortality is one of the Millennium Development Goals, so the public health importance of understanding and minimizing ..
  3. Impact of the P479L Variant in CPT1A on Infant Mortality in Alaska
    David M Koeller; Fiscal Year: 2011
    ..1436C?T sequence variant also have the highest rates of infant mortality in Alaska. Based on these observations the investigators hypothesize that homozygosity for the c...
  4. SPEAKER TRAVEL AND SCIENTIFIC SESSION SUPPORT FOR THE TERATOLOGY SOCIETY 50TH
    Christina Chambers; Fiscal Year: 2011
    ..Birth defects constitute a major public health concern in the world today and are the leading cause of infant mortality in the United States...
  5. Wireless At-Risk Infant Monitoring System
    JASON HOLMSTEDT; Fiscal Year: 2012
    ..S. and account for approximately 69% of annual infant deaths;the remaining 31% [1,2] of infant mortality is attributable to known at-risk infants and other deaths (e.g., sudden infant death syndrome)...
  6. The effect of trichloroethylene exposure on adverse pregnancy outcomes
    Iman Hassan; Fiscal Year: 2013
    ..small for gestational age, intrauterine growth restriction and stillbirth,are significant determinants of infant mortality and morbidity [1, 2]...
  7. Mouse models of genomic instability and birth defects
    CATHERINE ELIZABETH KEEGAN; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Birth defects are the leading cause of infant mortality in the United States, accounting for 1 in 5 infant deaths annually...
  8. BRAINSTEM MATURATION IN THE SUDDEN INFANT DEATH SYNDROME
    HANNAH CHASE KINNEY; Fiscal Year: 2013
    ..provided by applicant): The sudden infant death syndrome (SIDS) is the leading cause of postneonatal infant mortality in the United States today...
  9. High-affinity RNA targets of Survival Motor Neuron Protein
    Ravindra N Singh; Fiscal Year: 2013
    ..Based on the frequency of occurrence, SMA is ranked as the second leading genetic cause of infant mortality after cystic fibrosis...
  10. Biochemical, Biomechanical & Morphological Properties of Quantitative Ultrasound
    Barbara L McFarlin; Fiscal Year: 2010
    ..In the United States, prematurity is the second leading cause of infant mortality and the leading cause of infant mortality for African Americans...
  11. The upper airway and the Sudden Infant Death Syndrome
    Donald Bartlett; Fiscal Year: 2012
    ..Despite this success, SIDS remains a major contributor to infant mortality. Further progress in the prevention of SIDS is likely to require improved understanding of its pathogenesis...
  12. BRAINSTEM MATURATION IN THE SUDDEN INFANT DEATH SYNDROME
    Hannah C Kinney; Fiscal Year: 2010
    The sudden infant death syndrome (SEDS) is the leading cause of postneonatal infant mortality, with an overall incidence of 0.8/1000 live births. Its cause(s) is unknown...
  13. Testing Compounds that Increase SMN levels for Efficacy in Mouse Models of SMA
    Elliot J Androphy; Fiscal Year: 2010
    ..goal is to develop an effective drug treatment of spinal muscular atrophy, the leading genetic cause of infant mortality. PUBLIC HEALTH RELEVANCE: Spinal muscular atrophy (SMA), a form of muscular dystrophy, is the leading genetic ..
  14. The development of probiotic yeast as an inexpensive vaccine delivery platform
    TRACEY JANE LAMB; Fiscal Year: 2013
    ..provided by applicant): Infectious diseases of the gastrointestinal tract are a significant cause of infant mortality and morbidity in the developing world...
  15. Transforming Women's Health: Discovery, Development, and Delivery
    Ellen M Daley; Fiscal Year: 2012
    ..e. infant mortality, low birth weight, preterm birth) and are less likely to isit a dentist compared to women in the U.S...
  16. North Carolina Birth Defects Study To Evaluate Pregnancy Exposures (NC BD-STEPS)
    Andrew Olshan; Fiscal Year: 2013
    Project Abstract Birth defects are a leading cause of infant mortality, morbidity and healthcare costs in the United States, yet the etiology of most birth defects remains unknown...
  17. A geostatistical framework for the multi-scale boundary analysis of space-time tr
    PIERRE E GOOVAERTS; Fiscal Year: 2013
    ..geographical and racial disparities in temporal trends of several health outcomes (late-stage breast cancer, infant mortality and low birth weight), and the exploration of their relationships with potential factors, such as proximityto ..
  18. Small Oligonucleotides As Therapeutic Agents Of Spinal Muscular Atrophy
    Ravindra N Singh; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Spinal Muscular Atrophy (SMA) is a leading genetic cause of infant mortality. Most commonly, SMA results from the reduced levels of full-length SMN protein (SMN) in motor neurons and spinal chord due ..
  19. The survival of motor neuron protein in axonal mRNA localization
    PAUL GREGORY DONLIN-ASP; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Spinal muscular atrophy (SMA) is the leading genetic cause of infant mortality and the second most common autosomal recessive genetic disorder worldwide...
  20. CANCER AND CHANGING TRENDS IN US MORTALITY INEQUITIES: 1960-2004
    Nancy Krieger; Fiscal Year: 2010
    ..in socioeconomic health inequities has focused on such outcomes as all-cause mortality, life expectancy, or infant mortality, with analyses typically extending back only to the 1980s...
  21. Pregnancy and EARly Lifestyle improvement Study (PEARLS)
    Kaumudi J Joshipura; Fiscal Year: 2013
    ..and fruit, vegetable and whole grain intake, and the highest rates of diabetes, childhood obesity and infant mortality of all U.S...
  22. A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and Anxiety
    Michelle A Williams; Fiscal Year: 2013
    ..among reproductive age women, and are risk factors of preterm delivery (PTD) an important determinant of infant mortality. We submit that our research is significant and can make a difference insofar as helping to: (1) identify ..
  23. Does ArsenicMitigation in BangladeshRaiseExposure to Bacterial and ViralPathogens
    ALEXANDER FRANS VAN GEEN; Fiscal Year: 2010
    ..efforts by international organizations, including UNICEF, the Bangladesh government, and many NGOs to reduce infant mortality by encouraging a switch from surface water to groundwater, which is generally less contaminated with human ..
  24. Cooperative lead development program for treatment of spinal muscular atrophy
    Elliot J Androphy; Fiscal Year: 2012
    ..Spinal Muscular Atrophy (SMA) is a common form of muscular dystrophy and the leading genetic cause of infant mortality. This autosomal recessive disorder is characterized by progressive muscle weakness due to loss of motor ..
  25. Function of the Zinc Finger Protein ZPR1 in neurodegeneration
    LAXMAN DASS GANGWANI; Fiscal Year: 2013
    ..SMA is one of the leading causes of infant mortality in the United States with an estimated 7.5 million Americans as carriers of disease...
  26. Academic-Community Partnerships to Brdge Across the U.S. Pacific Islands
    Alice Tse; Fiscal Year: 2012
    ..Key areas of CBPR focus will likely include: infant mortality, obesity other nutritional disorders;and techniques for outreach and information dissemination...
  27. The role of the primitive choana in amniote craniofacial morphogenesis
    John Abramyan; Fiscal Year: 2013
    ..separating the choana from the nasal passage) in humans, which results in choanal atresia (CA), can lead to infant mortality. Several recent studies have identified genetic pathways which, when perturbed, can cause CA in mouse models...
  28. A Novel Oral Combination Pediatric HIV and TB Vaccine
    Michelle H Larsen; Fiscal Year: 2012
    ..Both HIV-1 and TB are major causes of infant mortality and morbidity in Africa, and the successful development of a combination vaccine effective against both ..
  29. Climate Change and Health: Assessing the Risk of Preterm Delivery
    Rupa Basu; Fiscal Year: 2013
    ..Pre-term delivery (PTD) is the leading cause of infant mortality and morbidity and among the top public health challenges facing our nation as well as the rest of the world...
  30. Maternal Intestinal Infections and Low Birth Weight in a Rural Indian Cohort
    RACHEL MARGARET WHELAN; Fiscal Year: 2012
    ..weight and preterm delivery are highly correlated and continue to be among the major refractory causes of infant mortality and childhood morbidity (Gutbrod et al, 2000)...
  31. Cooperative Multicenter Maternal Fetal Medicine Units Networks
    John M Thorp; Fiscal Year: 2013
    ..This is particularly important in North Carolina as the state ranks in the bottom third of the nation with regard to perinatal/maternal health and infant mortality.
  32. Regulation of SMN and Identification of its Downstream Target
    Judith Jebanathirajah Steen; Fiscal Year: 2013
    ..a disease caused by the mutations of Survival Motor Neuron 1 (SMN1) gene, is the most common genetic cause of infant mortality. Humans have two copies of the SMN gene, the telomeric SMN1, which encodes for a full-length form (FL-SMN), ..
  33. Effect of Prenatal Nicotinic Exposure on Control of Hypoxic Ventilatory Response
    Fadi Xu; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Sudden infant death syndrome (SIDS) is a leading cause of infant mortality. Cigarette smoke (nicotinic exposure) is the key risk factor and hypoxemia is an acute precursor for SIDS...
  34. The Ventral Medulla and the Sudden Infant Death Syndrome
    HANNAH CHASE KINNEY; Fiscal Year: 2013
    ..review of the history, autopsy, and death scene investigation;it is the leading cause of postneonatal infant mortality in the United States today...
  35. Impact of Sunflower Oil Massage on Neonatal Mortality in Nepal
    Luke C Mullany; Fiscal Year: 2013
    ..that can be delivered at the community level in low-resource settings to reduce neonatal and early infant mortality. There is increasing evidence of the role of the neonatal skin and the potential for newborn massage with ..
  36. Community-based interventions to reduce mortality from neonatal infection
    Waldemar A Carlo; Fiscal Year: 2012
    ..young infants with suspected serious bacterial infection may result in an important reduction in neonatal and infant mortality and morbidity worldwide...
  37. Iowa PRAMS Surveillance Program
    Gretchen Hageman; Fiscal Year: 2013
    ..Iowa's maternal-child health (MCH) priorities are to reduce infant mortality, address racial disparities in access to prenatal care and birth outcomes, reduce maternal smoking during ..
  38. A Neural Development mRNA Decay Network
    Michael Cleary; Fiscal Year: 2013
    ..most common form of hereditary mental impairment) and spinal muscular atrophy (a leading genetic cause of infant mortality)...
  39. Estimating Ultrasound Attenuation in Human Pregnant Cervix
    BARBARA L contact MCFARLIN; Fiscal Year: 2010
    ..In the United States, prematurity is the second leading cause of infant mortality and the leading cause of infant mortality for Black infants...
  40. Maryland Pregnancy Risk Assessment Monitoring System: population-based surveillan
    Diana Cheng; Fiscal Year: 2013
    ..The goal is to use generated data to identify ways to prevent maternal and infant mortality and morbidity...
  41. Michigan Pregnancy Risk Assessment and Monitoring System (MI PRAMS)
    Robert Wahl; Fiscal Year: 2013
    ..analyses to thus develop and implement targeted strategies for addressing racial disparities in maternal and infant mortality and morbidity...
  42. Gender Equity-Focused, Male-Centered Family Planning for Rural India
    Niranjan Saggurti; Fiscal Year: 2012
    ..These concerns are considered to drive the persistent and unacceptably high rates of maternal and infant mortality in India...
  43. Impact of TB on Outcome of HIV in Pregnant Women
    Richard E Chaisson; Fiscal Year: 2013
    ..and mortality, and may be associated with increased mother-to-child transmission (MTCT) of HIV and excess infant mortality. We have found that 2-3% of HIV-infected pregnant women in Soweto, South Africa, have previously undetected ..
  44. Regulation of cardiovascular transcription
    Brian L Black; Fiscal Year: 2013
    ..applicant): Congenital cardiac defects affect nearly 1% of all live births and are the most common cause of infant mortality in the United States...
  45. Effect of Air Pollution and Traffic on Birth Outcomes
    Michelle L Bell; Fiscal Year: 2012
    ..by investigator): Preterm delivery, intrauterine growth restriction and low birth weight are major causes of infant mortality and severe morbidity in the United States...
  46. Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirgh (PASS) Network
    Kimberly A Dukes; Fiscal Year: 2013
    ..The long-term goals of the Safe Passage Study are to decrease fetal and infant mortality and improve child health in communities at high risk for prenatal maternal alcohol consumption...
  47. MEHARRY CLINICAL RESEARCH CENTER
    Valerie Rice; Fiscal Year: 2009
    ..research including cancer, cardiovascular, infectious disease, HIV/AIDS, neurological/behavioral, and infant mortality. The MT will develop relationships with community health centers to expand CRC activities in population-based,..
  48. A Multimodality Approach to Estimating Newborn Brain Oxygen Metabolism (CMRO2)
    PATRICIA ELLEN GRANT; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Perinatal brain injury remains a significant cause of infant mortality and morbidity, occurring in over 6 out of every 1,000 live births...
  49. Bisphenol A and Phthalate Exposure in Relation to Fetal Growth and Preterm Birth
    John D Meeker; Fiscal Year: 2013
    DESCRIPTION (provided by investigator): Preterm birth is the leading cause of infant mortality worldwide, and also greatly increases the risk of developing serious health complications in childhood and throughout life...
  50. 2012 Craniofacial Morphogenesis &Tissue Regeneration GRS &GRC
    Robert E Maxson; Fiscal Year: 2012
    ..They are also a major cause of infant mortality. Collectively they have a dramatic impact on the cost of health care nationally...
  51. Pulmonary Blood Flow in Lung Development and Congenital Diaphragmatic Hernia
    Douglas A Potoka; Fiscal Year: 2013
    ..with pulmonary hypoplasia results in often severe respiratory distress in neonates with CDH resulting in high infant mortality of up to 40%...
  52. Regulation and function of innate lymphoid cells in the gut
    David Artis; Fiscal Year: 2013
    ..by bacterial-induced diarrhea and the associated dehydration represents the second most common cause of infant mortality around the world...
  53. Synapse Loss in Spinal Muscular Atrophy
    Chien Ping Ko; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Proximal Spinal Muscular Atrophy (SMA), a leading genetic cause of infant mortality, is an autosomal recessive disease characterized by the loss of spinal motoneurons, muscle atrophy, and motor ..
  54. Innovative Approaches to Inform Evidence-Based Pregnancy Weight Gain Guidelines
    JENNIFER ANNE HUTCHEON; Fiscal Year: 2013
    ..and maternal postpartum body mass index change at 22 years postpartum) and offspring (stillbirth, infant mortality, spontaneous preterm birth, small- and large-for-gestational-age births, neurocognitive deficits, child ..
  55. A Study of Heterologous Immunity Induced by Neonatal BCG Vaccination
    Daniel H Libraty; Fiscal Year: 2012
    ..against disseminated forms of tuberculosis, BCG vaccination has also been reported to reduce overall infant mortality and suggested to have beneficial heterologous immune effects...
  56. Exome Sequencing in Familial Cardiovascular Malformations
    KIM LEWIS MCBRIDE; Fiscal Year: 2012
    ..to provide better risk counseling for a group of malformations that contribute to a large proportion of infant mortality due to birth defects...
  57. Oklahoma Pregnancy Risk Assessment Monitoring System (PRAMS): Category B[Existing
    JOYCE Y MARSHALL; Fiscal Year: 2013
    ..Those priorities are: reduce infant mortality;improve access to comprehensive health services for the MCH population;reduce the prevalence of tobacco use ..
  58. Study of Attitudes and Factors Affecting Infant Care
    Michael J Corwin; Fiscal Year: 2013
    ..RELEVANCE: Since SIDS is the most common cause of infant mortality beyond the neonatal period, and adherence to safe infant sleep practices has been proven to reduce the risk ..
  59. Inflammatory Cytokine Polymorphisms, Air Pollution, and Very Preterm Birth
    Ondine von Ehrenstein; Fiscal Year: 2013
    ..VPTB is the most frequent cause of infant mortality in the US, and a main contributor to neurological and pulmonary disorders in children with infants born at ..
  60. Informing Evidence-based Maternal Weight Gain Guidelines for Twin Pregnancies
    JENNIFER ANNE HUTCHEON; Fiscal Year: 2013
    ..preeclampsia, unplanned cesarean delivery, weight retention at 5 years postpartum) and offspring (stillbirth, infant mortality, spontaneous preterm birth <32 weeks, abnormal fetal growth, child overweight, and poor cognitive ..
  61. Neonatal EEG Monitor
    Tammy Tsuchida; Fiscal Year: 2012
    ..systems can help diagnose and treat neonatal seizures and thus potentially reduce neurological disorders or infant mortality. This application aims to address the challenges of neonatal EEG by developing a portable, wireless, dry-..
  62. Building Partnerships to Enhance Health and Health Care Delivery in Alabama and G
    RUEBEN CLIFTON WARREN; Fiscal Year: 2012
    ..Cardiovascular diseases and stroke, chemical dependency, diabetes, homicide and accidents, HIV/AIDS and infant mortality added to cancer account for more than 80 percent of the excess mortality observed among Blacks and other ..
  63. MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS
    T O SHEA; Fiscal Year: 2005
    ..Multicenter Neonatal Research Network is to contribute to the identification of therapies to reduce infant mortality and morbidity ...
  64. Air Pollution and Adverse Birth Outcomes
    Beate Ritz; Fiscal Year: 2004
    ..abstract_text> ..
  65. KANGAROO MOTHER CARE TO PREVENT INFANT MORTALITY
    Nancy Sloan; Fiscal Year: 2001
    ..Dramatic improvements in child survival in developing countries, there is limited success in reducing infant mortality. The Kangaroo Mother Care (KMC) method, whereby hospital-born stabilized LBW newborns are placed in an ..
  66. MECHANISM OF CARBOHYDRATE TRANSPORT IN BACTERIA
    Milton Saier; Fiscal Year: 2000
    ..They are primary causes of infant mortality, malnutrition and retarded mental and physical development worldwide...
  67. RACE AND ETHNIC DIFFERENCES IN U.S. BIRTH OUTCOMES
    Michael Grossman; Fiscal Year: 1990
    ..and cause-specific postneonatal mortality for whites and blacks as the outcomes), states (the 1980 National Infant Mortality Surveillance with race-specific postneonatal mortality by birthweight and cause, by birthweight and mother's ..
  68. A Collaborative, Intersectional Approach to Health Disparities in Pregnancy
    Tina Bloom; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): Serious health disparities in pregnancy outcomes (maternal and infant mortality, preterm birth, and low birth weight) exist, and in many cases, are growing worse...
  69. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..We do not have contemporary, nationally representative, population-based estimates of the increased infant mortality risk associated with multiple pregnancies...
  70. MYOMETRIAL GAP JUNCTION MODULATION IN PRETERM LABOR
    WILLIAM LARSEN; Fiscal Year: 1990
    Preterm labor is a major cause of infant mortality in the United States and results in major medical expenditures for the care of surviving infants...
  71. Congenital and neonatal malaria in Mali
    Abdoulaye Djimde; Fiscal Year: 2006
    ..In the West African nation of Mali, malaria is indeed the lead killer disease. Nationwide, infant mortality rate is estimated to be 149 per thousand live births while the mortality rate for neonates (age 0-28 days) is ..
  72. Immortalization of Pregnant Human Myometrial Cells
    MELVYN SOLOFF; Fiscal Year: 2004
    Preterm birth is the leading cause of infant mortality, yet we know little of human myometrial signals that initiate of labor contractions in normal-length pregnancies, let alone preterm pregnancies...
  73. Formula with antimicrobials to decrease infant mortality
    Koteswara Chintalacharuvu; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  74. COSTS OF CARE FOR VLBW INFANTS
    Jeannette Rogowski; Fiscal Year: 2002
    ..The high rates of infant mortality in the United States are concentrated among these babies...
  75. Identification of Factors Influencing Climbing Fiber Neuron Fate in the Dorsal Hi
    REBECCA LANDSBERG; Fiscal Year: 2009
    ..syndromes, autism, fetal alcohol syndrome, and sudden infant death syndrome (SIDS), the leading cause of infant mortality in the United States...
  76. MORTALITY BY RACE AMONG LOW BIRTH WEIGHT INFANTS
    Robert Michielutte; Fiscal Year: 1990
    The primary goal of the proposed study is to examine the relationship between race and infant mortality in the context of a general model of risk factors for infant mortality...
  77. Nitrates, Nitrites, and Nitrosatable Drugs and Risk of Selected Birth Defects
    JEAN DIANE BRENDER; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Congenital defects remain the greatest contributor to infant mortality;yet, the causes for the majority of these defects are either unknown or poorly understood...
  78. A Novel Approach to the Development of a Syphilis Vaccine Using Rabbit Monoclonal
    James Miller; Fiscal Year: 2009
    Syphilis is a global public health problem that results in significant morbidity and infant mortality. The continued worldwide prevalence of adult and congenital syphilis, and the increased risk of transmitting HIV infection in patients ..