hospital mortality

Summary

Summary: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.

Top Publications

  1. ncbi Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    D C Angus
    Critical Care Medicine Division, Department of Anesthesiology and Critical Care Medicine, and the Center for Research on Health Care, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 29:1303-10. 2001
  2. ncbi The epidemiology of sepsis in the United States from 1979 through 2000
    Greg S Martin
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Emory University School of Medicine, Atlanta, USA
    N Engl J Med 348:1546-54. 2003
  3. ncbi Comorbidity measures for use with administrative data
    A Elixhauser
    MEDTAP International, Inc, Bethesda, MD 20814, USA
    Med Care 36:8-27. 1998
  4. ncbi Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
    Anand Kumar
    Section of Critical Care Medicine, Health Sciences Centre St Boniface Hospital, University of Manitoba, Winnipeg, MB, Canada
    Crit Care Med 34:1589-96. 2006
  5. ncbi Sepsis in European intensive care units: results of the SOAP study
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care Med 34:344-53. 2006
  6. ncbi Acute renal failure in critically ill patients: a multinational, multicenter study
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    JAMA 294:813-8. 2005
  7. ncbi Acute kidney injury, mortality, length of stay, and costs in hospitalized patients
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118 1211, USA
    J Am Soc Nephrol 16:3365-70. 2005
  8. ncbi Incidence and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
    N Engl J Med 353:1685-93. 2005
  9. ncbi Early goal-directed therapy in the treatment of severe sepsis and septic shock
    E Rivers
    Department of Emergency Medicine, Henry Ford Health Systems, Case Western Reserve University, Detroit, MI 48202, USA
    N Engl J Med 345:1368-77. 2001
  10. ncbi Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data
    Hude Quan
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Med Care 43:1130-9. 2005

Detail Information

Publications311 found, 100 shown here

  1. ncbi Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    D C Angus
    Critical Care Medicine Division, Department of Anesthesiology and Critical Care Medicine, and the Center for Research on Health Care, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 29:1303-10. 2001
    ..To determine the incidence, cost, and outcome of severe sepsis in the United States...
  2. ncbi The epidemiology of sepsis in the United States from 1979 through 2000
    Greg S Martin
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Emory University School of Medicine, Atlanta, USA
    N Engl J Med 348:1546-54. 2003
    ..We investigated the epidemiology of sepsis in the United States, with specific examination of race and sex, causative organisms, the disposition of patients, and the incidence and outcome...
  3. ncbi Comorbidity measures for use with administrative data
    A Elixhauser
    MEDTAP International, Inc, Bethesda, MD 20814, USA
    Med Care 36:8-27. 1998
    ..This study attempts to develop a comprehensive set of comorbidity measures for use with large administrative inpatient datasets...
  4. ncbi Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
    Anand Kumar
    Section of Critical Care Medicine, Health Sciences Centre St Boniface Hospital, University of Manitoba, Winnipeg, MB, Canada
    Crit Care Med 34:1589-96. 2006
    ..To determine the prevalence and impact on mortality of delays in initiation of effective antimicrobial therapy from initial onset of recurrent/persistent hypotension of septic shock...
  5. ncbi Sepsis in European intensive care units: results of the SOAP study
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care Med 34:344-53. 2006
    ..To better define the incidence of sepsis and the characteristics of critically ill patients in European intensive care units...
  6. ncbi Acute renal failure in critically ill patients: a multinational, multicenter study
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    JAMA 294:813-8. 2005
    ....
  7. ncbi Acute kidney injury, mortality, length of stay, and costs in hospitalized patients
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118 1211, USA
    J Am Soc Nephrol 16:3365-70. 2005
    The marginal effects of acute kidney injury on in-hospital mortality, length of stay (LOS), and costs have not been well described...
  8. ncbi Incidence and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
    N Engl J Med 353:1685-93. 2005
    ..Despite recent advances in our understanding of the mechanism and treatment of acute lung injury, its incidence and outcomes in the United States have been unclear...
  9. ncbi Early goal-directed therapy in the treatment of severe sepsis and septic shock
    E Rivers
    Department of Emergency Medicine, Henry Ford Health Systems, Case Western Reserve University, Detroit, MI 48202, USA
    N Engl J Med 345:1368-77. 2001
    ..The purpose of this study was to evaluate the efficacy of early goal-directed therapy before admission to the intensive care unit...
  10. ncbi Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data
    Hude Quan
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Med Care 43:1130-9. 2005
    ..Recognizing this, we conducted a multistep process to develop ICD-10 coding algorithms to define Charlson and Elixhauser comorbidities in administrative data and assess the performance of the resulting algorithms...
  11. ncbi Predictors of hospital mortality in the global registry of acute coronary events
    Christopher B Granger
    Division of Cardiology, University Medical Center, Durham, NC, USA
    Arch Intern Med 163:2345-53. 2003
    ..Management of acute coronary syndromes (ACS) should be guided by an estimate of patient risk...
  12. ncbi The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis
    Mitchell M Levy
    Division of Pulmonary, Sleep and Critical Care Medicine Care Medicine, Brown University School of Medicine, Rhode Island Hospital, Providence, RI, USA
    Crit Care Med 38:367-74. 2010
    ..A performance improvement initiative targeted changing clinical behavior (process improvement) via bundles based on key SSC guideline recommendations...
  13. ncbi Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study
    Andres Esteban
    Unidad de Cuidados Intensivos, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 5, 28905 Getafe, Madrid, Spain
    JAMA 287:345-55. 2002
    ..The outcome of patients receiving mechanical ventilation for particular indications has been studied, but the outcome in a large number of unselected, heterogeneous patients has not been reported...
  14. ncbi International study of the prevalence and outcomes of infection in intensive care units
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    JAMA 302:2323-9. 2009
    ..Infection is a major cause of morbidity and mortality in intensive care units (ICUs) worldwide. However, relatively little information is available about the global epidemiology of such infections...
  15. ncbi Adverse events and potentially preventable deaths in Dutch hospitals: results of a retrospective patient record review study
    M Zegers
    NIVEL, Netherlands Institute for Health Services Research, Utrecht, The Netherlands
    Qual Saf Health Care 18:297-302. 2009
    ..This study determined the incidence, type, nature, preventability and impact of adverse events (AEs) among hospitalised patients and potentially preventable deaths in Dutch hospitals...
  16. ncbi Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock
    Mark E Mikkelsen
    Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Crit Care Med 37:1670-7. 2009
    ..e., refractory hypotension)...
  17. ncbi Nurse-staffing levels and the quality of care in hospitals
    Jack Needleman
    Department of Health Policy and Management, Harvard School of Public Health, Boston, Mass 02115, USA
    N Engl J Med 346:1715-22. 2002
    ..It is uncertain whether lower levels of staffing by nurses at hospitals are associated with an increased risk that patients will have complications or die...
  18. ncbi Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    Kirkwood F Adams
    Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA
    Am Heart J 149:209-16. 2005
    ..Most available data on these patients are limited by patient selection criteria and study design of clinical trials and single-center studies...
  19. ncbi Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine
    J L Vincent
    Department of Intensive Care, Erasme University Hospital, Brussels, Belgium
    Crit Care Med 26:1793-800. 1998
    ..To evaluate the use of the Sequential Organ Failure Assessment (SOFA) score in assessing the incidence and severity of organ dysfunction in critically ill patients...
  20. ncbi Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients
    F Roques
    Service de chirurgie cardiovasculaire, CHU de Fort de France, Martinique, France
    Eur J Cardiothorac Surg 15:816-22; discussion 822-3. 1999
    ..To assess risk factors for mortality in cardiac surgical adult patients as part of a study to develop a European System for Cardiac Operative Risk Evaluation (EuroSCORE)...
  21. pmc Evidence of methodological bias in hospital standardised mortality ratios: retrospective database study of English hospitals
    Mohammed A Mohammed
    Unit of Public Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham B15 2TT
    BMJ 338:b780. 2009
    ..To assess the validity of case mix adjustment methods used to derive standardised mortality ratios for hospitals, by examining the consistency of relations between risk factors and mortality across hospitals...
  22. ncbi Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009
    Seema Jain
    Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 361:1935-44. 2009
    ..We describe the clinical characteristics of patients who were hospitalized with 2009 H1N1 influenza in the United States from April 2009 to mid-June 2009...
  23. ncbi Hospital nurse staffing and patient mortality, nurse burnout, and job dissatisfaction
    Linda H Aiken
    Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, 420 Guardian Dr, Philadelphia, PA 19104 6096, USA
    JAMA 288:1987-93. 2002
    ....
  24. ncbi Hospital volume and surgical mortality in the United States
    John D Birkmeyer
    Veterans Affairs Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT 05009, USA
    N Engl J Med 346:1128-37. 2002
    ..Although numerous studies suggest that there is an inverse relation between hospital volume of surgical procedures and surgical mortality, the relative importance of hospital volume in various surgical procedures is disputed...
  25. pmc Developing a summary hospital mortality index: retrospective analysis in English hospitals over five years
    Michael J Campbell
    ScHARR, University of Sheffield, Sheffield S1 4DA, UK
    BMJ 344:e1001. 2012
    ....
  26. ncbi Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward
    Andres Esteban
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 35:1284-9. 2007
    ..To describe the outcome of patients with sepsis according to location on a ward or in an intensive care unit...
  27. ncbi Comparison of the Elixhauser and Charlson/Deyo methods of comorbidity measurement in administrative data
    Danielle A Southern
    Department of Community Health Sciences and The Centre for Health and Policy Studies, University of Calgary, Calgary, Alberta, Canada
    Med Care 42:355-60. 2004
    ..However, a new method defined by Elixhauser et al. has been introduced recently and could be superior, although it has not been validated widely...
  28. ncbi Weekend mortality for emergency admissions. A large, multicentre study
    Paul Aylin
    Dr Foster Unit at Imperial College, Department of Primary Care and Social Medicine, Imperial College London, London SW7 2AZ, UK
    Qual Saf Health Care 19:213-7. 2010
    ..Several studies have identified higher mortality for patients admitted as emergencies at the weekend compared with emergency admissions during the week, but most have focused on specific conditions or have had a limited sample size...
  29. ncbi A national evaluation of the effect of trauma-center care on mortality
    Ellen J MacKenzie
    Johns Hopkins Bloomberg School of Public Health, Center for Injury Research and Policy, Baltimore, MD 21205 1996, USA
    N Engl J Med 354:366-78. 2006
    ..To address this gap, we examined differences in mortality between level 1 trauma centers and hospitals without a trauma center (non-trauma centers)...
  30. ncbi Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome
    Kenneth P Steinberg
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Box 359762, 325 Ninth Ave, Seattle, WA 98104, USA
    N Engl J Med 354:1671-84. 2006
    ..Because previous reports suggested that corticosteroids may improve survival, we performed a multicenter, randomized controlled trial of corticosteroids in patients with persistent ARDS...
  31. ncbi The association between hospital overcrowding and mortality among patients admitted via Western Australian emergency departments
    Peter C Sprivulis
    Department of Emergency Medicine, University of Western Australia, 2nd Floor R Block, Queen Elizabeth II, Medical Centre, Verdun Street, Nedlands, WA 6009, Australia
    Med J Aust 184:208-12. 2006
    ..To examine the relationship between hospital and emergency department (ED) occupancy, as indicators of hospital overcrowding, and mortality after emergency admission...
  32. pmc Acute kidney injury and mortality in hospitalized patients
    Henry E Wang
    Department of Emergency Medicine, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Am J Nephrol 35:349-55. 2012
    ..The objective of this study was to determine the incidence of acute kidney injury (AKI) and its relation with mortality among hospitalized patients...
  33. ncbi The DECAF Score: predicting hospital mortality in exacerbations of chronic obstructive pulmonary disease
    John Steer
    Department of Respiratory Medicine, North Tyneside General Hospital, Rake Lane, North Shields, UK
    Thorax 67:970-6. 2012
    ..For exacerbations complicated by pneumonia, the CURB-65 prognostic tool is frequently used but its use in this population is suboptimal...
  34. ncbi Mortality among patients admitted to hospitals on weekends as compared with weekdays
    C M Bell
    Department of Medicine, University of Toronto, Sunnybrook and Women's College Health Sciences Centre, ON, Canada
    N Engl J Med 345:663-8. 2001
    ..It is uncertain whether in-hospital mortality rates among patients with serious conditions differ according to whether they are admitted on a weekend or ..
  35. ncbi The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis
    J G F Cleland
    Department of Cardiology, University of Hull, Castle Hill Hospital, Castle Road, Kingston upon Hull HU16 5JQ UK
    Eur Heart J 24:442-63. 2003
    ..Accordingly, the EuroHeart Failure survey was conducted to ascertain if appropriate tests were being performed with which to confirm or refute a diagnosis of heart failure and how this influenced subsequent management...
  36. ncbi Hospital mortality, length of stay, and preventable complications among critically ill patients before and after tele-ICU reengineering of critical care processes
    Craig M Lilly
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    JAMA 305:2175-83. 2011
    The association of an adult tele-intensive care unit (ICU) intervention with hospital mortality, length of stay, best practice adherence, and preventable complications for an academic medical center has not been reported.
  37. pmc Impact of a statewide intensive care unit quality improvement initiative on hospital mortality and length of stay: retrospective comparative analysis
    Allison Lipitz-Snyderman
    Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 624 N Broadway, Baltimore, MD 21205, USA
    BMJ 342:d219. 2011
    ..ICU project, a comprehensive statewide quality improvement initiative focused on reduction of infections, was associated with reductions in hospital mortality and length of stay for adults aged 65 or more admitted to intensive care units.
  38. ncbi The more the better?: the impact of surgeon and hospital volume on in-hospital mortality following colorectal resection
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Ann Surg 249:954-9. 2009
    To determine the in-hospital mortality rates for patients undergoing colorectal resection for malignant or benign conditions, and to identify risk factors for in-hospital death, particularly the relationships with surgeon and hospital ..
  39. ncbi Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients
    Philipp G H Metnitz
    Department of Reanimation Medicale, Hopital St Louis, University Lariboisière St Louis, Paris, France
    Crit Care Med 30:2051-8. 2002
    ..renal failure is a complication in critically ill patients that has been associated with an excess risk of hospital mortality. Whether this reflects the severity of the disease or whether acute renal failure is an independent risk ..
  40. ncbi Is worsening multiple organ failure the cause of death in patients with severe sepsis?
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Crit Care Med 39:1050-5. 2011
    ..We used the INDEPTH (International Integrated Database for the Evaluation of Severe Sepsis and Drotrecogin alfa activated) database to investigate the reported cause of death in patients with severe sepsis...
  41. pmc An administrative claims model for profiling hospital 30-day mortality rates for pneumonia patients
    Dale W Bratzler
    Oklahoma Foundation for Medical Quality, Oklahoma City, Oklahoma, United States of America
    PLoS ONE 6:e17401. 2011
    ..We sought to develop and validate a hierarchical regression model using Medicare claims data that produces hospital-level, risk-standardized 30-day mortality rates useful for public reporting for patients hospitalized with pneumonia...
  42. ncbi EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population
    Markku S Nieminen
    Division of Cardiology, Department of Medicine, Helsinki University Central Hospital, Haartmaninkatu 4, PO Box 340, 00029 HUS, Finland
    Eur Heart J 27:2725-36. 2006
    ....
  43. pmc Brazilian Sepsis Epidemiological Study (BASES study)
    Eliezer Silva
    Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
    Crit Care 8:R251-60. 2004
    ..This study was designed to verify the actual incidence density and outcome of sepsis in Brazilian ICUs. We also assessed the association between the Consensus Conference criteria and outcome..
  44. pmc Nonrecovery of kidney function and death after acute on chronic renal failure
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:891-8. 2009
    ..Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure)...
  45. ncbi An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with heart failure
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Circulation 113:1693-701. 2006
    ..A model using administrative claims data that is suitable for profiling hospital performance for heart failure would be useful in quality assessment and improvement efforts...
  46. ncbi New ICD-10 version of the Charlson comorbidity index predicted in-hospital mortality
    Vijaya Sundararajan
    Victorian Department of Human Services, Level 18, 120 Spencer Street, Melbourne, 3000 Victoria, Australia
    J Clin Epidemiol 57:1288-94. 2004
    ..With the transition into ICD-10 coding worldwide, an ICD-10 version of the Deyo adaptation was developed and validated using population-based hospital data from Victoria, Australia...
  47. ncbi Quality of care information makes a difference: an analysis of market share and price changes after publication of the New York State Cardiac Surgery Mortality Reports
    D B Mukamel
    Department of Community and Preventive Medicine, University of Rochester Medical Center, NY, USA
    Med Care 36:945-54. 1998
    ..The authors test the hypotheses that hospitals and surgeons with better outcomes reported in the NYS Cardiac Surgery Reports experience a relative increase in their market share and prices...
  48. ncbi Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality
    Christina M Wyatt
    Division of Nephrology, Department of Medicine, Mount Sinai Medical Center, New York, NY 10029 6574, USA
    AIDS 20:561-5. 2006
    ..Kidney disease is an increasingly important complication of HIV...
  49. pmc The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada
    G Ross Baker
    Department of Health Policy, Management and Evaluation, University of Toronto, McMurrich Building Room 2031, 12 Queen s Park Crescent West, Toronto, Ontario M5S 1A8, Canada
    CMAJ 170:1678-86. 2004
    ..AEs are unintended injuries or complications resulting in death, disability or prolonged hospital stay that arise from health care management. We estimated the incidence of AEs among patients in Canadian acute care hospitals...
  50. ncbi Predictors of in-hospital mortality and attributable risks of death after ischemic stroke: the German Stroke Registers Study Group
    Peter U Heuschmann
    Institute of Epidemiology and Social Medicine, University of Muenster, Muenster, Germany
    Arch Intern Med 164:1761-8. 2004
    ..We investigated predictors for in-hospital mortality and attributable risks of death after ischemic stroke in a pooled analysis of large German stroke registers.
  51. ncbi Use of comorbidity scores for control of confounding in studies using administrative databases
    S Schneeweiss
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 29:891-8. 2000
    ..Our objective was to compare metrical and practical properties of published comorbidity scores for use in epidemiological research with administrative databases...
  52. ncbi Variation in hospital mortality associated with inpatient surgery
    Amir A Ghaferi
    Michigan Surgical Collaborative for Outcomes Research and Evaluation, The Department of Surgery, University of Michigan, Ann Arbor 48104, USA
    N Engl J Med 361:1368-75. 2009
    b>Hospital mortality that is associated with inpatient surgery varies widely. Reducing rates of postoperative complications, the current focus of payers and regulators, may be one approach to reducing mortality...
  53. pmc Effects of nurse staffing and nurse education on patient deaths in hospitals with different nurse work environments
    Linda H Aiken
    Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, PA 19104 4217, USA
    Med Care 49:1047-53. 2011
    ..more educated nurses, and improved nurse work environments have been shown to be associated with lower hospital mortality. Little is known about whether and under what conditions each type of investment works better to improve ..
  54. ncbi A validated risk score for in-hospital mortality in patients with heart failure from the American Heart Association get with the guidelines program
    Pamela N Peterson
    Denver Health Medical Center, Denver, CO, USA
    Circ Cardiovasc Qual Outcomes 3:25-32. 2010
    ..Our objective was to derive and validate a risk score for in-hospital mortality in patients hospitalized with heart failure using American Heart Association Get With the Guidelines-Heart ..
  55. ncbi Severe bloodstream infections: a population-based assessment
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary Health Region, and Calgary Laboratory Services, Calgary, Alberta, Canada
    Crit Care Med 32:992-7. 2004
    ..We sought to define the incidence and microbiology of severe bloodstream infection (bloodstream infection associated with intensive care unit admission within 48 hrs) and assess risk factors for acquisition and death...
  56. pmc The hospital standardised mortality ratio: a powerful tool for Dutch hospitals to assess their quality of care?
    B Jarman
    Dr Foster Unit, Faculty of Medicine, Imperial College London EC1A 9LA, UK
    Qual Saf Health Care 19:9-13. 2010
    ..To use the hospital standardised mortality ratio (HSMR), as a tool for Dutch hospitals to analyse their death rates by comparing their risk-adjusted mortality with the national average...
  57. ncbi Factors influencing in-hospital mortality and morbidity in patients treated on a stroke unit
    Hans Christian Koennecke
    Department of Neurology, Vivantes Klinikum im Friedrichshain, Berlin, Germany
    Neurology 77:965-72. 2011
    To determine the extent that demographics, clinical characteristics, comorbidities, and complications contribute to the risk of in-hospital mortality and morbidity in acute stroke.
  58. ncbi Effects of the introduction of the WHO "Surgical Safety Checklist" on in-hospital mortality: a cohort study
    W A Van Klei
    Division of Perioperative Care and Emergency Medicine, University Medical Centre Utrecht, Utrecht, NL
    Ann Surg 255:44-9. 2012
    ..To evaluate the effect of implementation of the WHO's Surgical Safety Checklist on mortality and to determine to what extent the potential effect was related to checklist compliance...
  59. ncbi Association of age and sex with myocardial infarction symptom presentation and in-hospital mortality
    John G Canto
    Watson Clinic and Lakeland Regional Medical Center, Lakeland, Florida 33805, USA
    JAMA 307:813-22. 2012
    ..However, few studies have taken age into account when examining sex differences in clinical presentation and mortality...
  60. pmc Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 4:e7782. 2009
    ..We conducted a prospective observational study reporting the management and outcomes of severely septic patients in two Ugandan hospitals. We describe their epidemiology, management, and clinical correlates for mortality...
  61. ncbi Female gender is an independent predictor of in-hospital mortality after STEMI in the era of primary PCI: insights from the greater Paris area PCI Registry
    Hakim Benamer
    European Hospital of Paris La Roseraie, Aubervilliers, France
    EuroIntervention 6:1073-9. 2011
    To determine if female gender is an independent predictor of in-hospital mortality after percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI)...
  62. ncbi The association of registered nurse staffing levels and patient outcomes: systematic review and meta-analysis
    Robert L Kane
    University of Minnesota School of Public Health, Minneapolis, Minnesota 55455, USA
    Med Care 45:1195-204. 2007
    ..To examine the association between registered nurse (RN) staffing and patient outcomes in acute care hospitals...
  63. pmc Hospital standardized mortality ratio: consequences of adjusting hospital mortality with indirect standardization
    Maurice E Pouw
    Department of Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS ONE 8:e59160. 2013
    ..Different methods can be used to standardize the hospital mortality ratio...
  64. pmc Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 12:R161. 2008
    ..To systematically review studies evaluating the performance of Sequential Organ Failure Assessment (SOFA)-based models for predicting mortality in patients in the intensive care unit (ICU)...
  65. ncbi Risk factors for in-hospital mortality of visceral leishmaniasis patients in eastern Uganda
    Yolanda Mueller
    Medecins Sans Frontieres, Geneva, Switzerland
    Trop Med Int Health 14:910-7. 2009
    To identify risk factors for in-hospital mortality in patients treated for visceral leishmaniasis (VL) in Uganda.
  66. ncbi Promoting Global Research Excellence in Severe Sepsis (PROGRESS): lessons from an international sepsis registry
    R Beale
    Adult Intensive Care Unit, Guy s and St Thomas NHS Foundation Trust, St Thomas Hospital, Lambeth Palace Road, SE1 7EH, London, UK
    Infection 37:222-32. 2009
    ....
  67. ncbi Medical Emergency Triage and Treatment System (METTS): a new protocol in primary triage and secondary priority decision in emergency medicine
    Bengt R Widgren
    Department of Accident and Emergency Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
    J Emerg Med 40:623-8. 2011
    ..In many Emergency Department (ED) triage scoring systems, vital signs are not included as an assessment parameter...
  68. ncbi Serum lactate as a predictor of mortality in emergency department patients with infection
    Nathan I Shapiro
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Emerg Med 45:524-8. 2005
    ..We determine whether a serum venous lactate is associated with an increased risk of death in ED patients with infection...
  69. ncbi Occult hypoperfusion and mortality in patients with suspected infection
    Michael D Howell
    Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Medicine, KB 23, 330 Brookline Avenue, Boston, MA 02215, USA
    Intensive Care Med 33:1892-9. 2007
    To determine, in the early stages of suspected clinically significant infection, the independent relationship of the presenting venous lactate level to 28-day in-hospital mortality.
  70. ncbi Cytokine production and hospital mortality in patients with sepsis-induced stress hyperglycemia
    Leonidia Leonidou
    Department of Internal Medicine, Section of Infectious Diseases, Patras University Hospital, Rion Patras 26500, Greece
    J Infect 55:340-6. 2007
    To investigate whether stress hyperglycemia affects the production of the main pro- and anti-inflammatory cytokines and the 28-day hospital mortality in patients with severe sepsis.
  71. ncbi Nurse staffing and inpatient hospital mortality
    Jack Needleman
    Department of Health Services, University of California, Los Angeles, School of Public Health, Los Angeles, USA
    N Engl J Med 364:1037-45. 2011
    ..However, such studies have been criticized because they have not shown a direct link between the level of staffing and individual patient experiences and have not included sufficient statistical controls...
  72. pmc SAPS 3--From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission
    Rui P Moreno
    Unidade de Cuidados Intensivos Polivalente, Hospital de St António dos Capuchos, Centro Hospitalar de Lisboa zona central, Lisbon, Portugal
    Intensive Care Med 31:1345-55. 2005
    ..To develop a model to assess severity of illness and predict vital status at hospital discharge based on ICU admission data...
  73. ncbi Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States
    Vladimir Kaplan
    Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Respir Crit Care Med 165:766-72. 2002
    ..The sex differences are of concern and require further investigation...
  74. ncbi Patients readmitted to ICUs* : a systematic review of risk factors and outcomes
    A L Rosenberg
    Department of Anesthesiology and Critical Care, University of Michigan Medical Center, Ann Arbor 48109, USA
    Chest 118:492-502. 2000
    ..To evaluate the causes, risk factors, and mortality rates associated with unexpected readmission to medical and surgical ICUs...
  75. pmc Health care-associated pneumonia and community-acquired pneumonia: a single-center experience
    Scott T Micek
    Department of Pharmacy, Barnes Jewish Hospital, St Louis, MO, USA
    Antimicrob Agents Chemother 51:3568-73. 2007
    ..8%), methicillin-sensitive Staphylococcus aureus (13.8%), and Haemophilus influenzae (8.5%). The hospital mortality rate was statistically greater among patients with HCAP than among those with CAP (24.6% versus 9...
  76. pmc Trends in hospital volume and operative mortality for high-risk surgery
    Jonathan F Finks
    Center for Healthcare Outcomes and Policy and the Section of General Surgery, Department of Surgery, University of Michigan, Ann Arbor, USA
    N Engl J Med 364:2128-37. 2011
    ..It remains unknown whether referral patterns for high-risk surgery have changed as a result and how operative mortality has been affected...
  77. ncbi Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial
    Tim C Jansen
    Department of Intensive Care, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
    Am J Respir Crit Care Med 182:752-61. 2010
    ..It is unknown whether lactate monitoring aimed to decrease levels during initial treatment in critically ill patients improves outcome...
  78. ncbi Site of bleeding and early outcome in primary intracerebral hemorrhage
    A Arboix
    Acute Stroke Unit, Department of Neurology, Hospital del Sagrat Cor, Barcelona, Spain
    Acta Neurol Scand 105:282-8. 2002
    ..To describe the influence of the site of the bleeding on clinical spectrum and early outcome of patients with acute spontaneous intracerebral hemorrhage (ICH)...
  79. ncbi A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patients
    Sean M Bagshaw
    Division of Critical Care Medicine, University of Alberta Hospital, 3C1 16 Walter C Mackenzie Centre, 8440 122 Street, Edmonton, Alberta T6G2B7, Canada
    Nephrol Dial Transplant 23:1203-10. 2008
    ..We sought to evaluate the RIFLE criteria on the day of ICU admission in a large heterogenous population of critically ill patients...
  80. ncbi Sex differences in medical care and early death after acute myocardial infarction
    Hani Jneid
    Division of Cardiology, Michael E DeBakey VA Medical Center and Baylor College of Medicine, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Circulation 118:2803-10. 2008
    ..It is unclear whether efforts undertaken to improve AMI care have mitigated these sex disparities in the current era...
  81. ncbi Effect of age, polymicrobial disease, and maternal HIV status on treatment response and cause of severe pneumonia in South African children: a prospective descriptive study
    Lisa M McNally
    Centre for International Child Health and Development, Institute of Child Health, University College London, London WC1N 1EH, UK
    Lancet 369:1440-51. 2007
    ..We aimed to measure predictors of treatment failure and the cause of non-responsive pneumonia in children admitted to hospital with severe pneumonia in Durban, South Africa...
  82. ncbi Association between clinically abnormal observations and subsequent in-hospital mortality: a prospective study
    Michael Buist
    Department of Intensive Care, Dandenong Hospital, P O Box 478, Dandenong, VIC 3175, Australia
    Resuscitation 62:137-41. 2004
    ..Previous studies have suggested that a medical emergency team responding to such patients may decrease in-hospital mortality from cardiac arrest, but the association between any abnormal clinical observation and subsequent increased ..
  83. ncbi The epidemiology of severe sepsis in children in the United States
    R Scott Watson
    Department of Critical Care Medicine, Center for Research on Health Care, and the CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Respir Crit Care Med 167:695-701. 2003
    ..60 versus 0.52 per 1,000, p < 0.001). Hospital mortality was 10.3%, or 4,383 deaths nationally (6.2 per 100,000 population)...
  84. ncbi Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Chest 115:462-74. 1999
    To evaluate the relationship between inadequate antimicrobial treatment of infections (both community-acquired and nosocomial infections) and hospital mortality for patients requiring ICU admission.
  85. ncbi Prognosis of patients on extracorporeal membrane oxygenation: the impact of acute kidney injury on mortality
    Yung Chang Chen
    Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Ann Thorac Surg 91:137-42. 2011
    ....
  86. ncbi Baseline characteristics, management practices, and long-term outcomes of Middle Eastern patients in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-2)
    Khalid F AlHabib
    King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:9-18. 2012
    ..We evaluated the clinical features, management, in-hospital, and long-term outcomes of in such a population...
  87. ncbi Epidemiology of critical care syndromes, organ failures, and life-support interventions in a suburban US community
    Rodrigo Cartin-Ceba
    Multidisciplinary Epidemiology and Translational Research in Intensive Care M E T R I C, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Chest 140:1447-55. 2011
    ..We aimed to determine the incidence of critical care syndromes, organ failures, and life-support interventions in a defined US suburban community with unrestricted access to critical care services...
  88. ncbi Representativeness of the Get With The Guidelines-Stroke Registry: comparison of patient and hospital characteristics among Medicare beneficiaries hospitalized with ischemic stroke
    Mathew J Reeves
    Department of Epidemiology, Michigan State University, B601 West Fee Hall, East Lansing, Michigan 48824, USA
    Stroke 43:44-9. 2012
    ..We used fee-for-service Medicare claims to ascertain the representativeness of ischemic stroke admissions in GWTG-Stroke...
  89. ncbi Trends in presenting characteristics and hospital mortality among patients with ST elevation and non-ST elevation myocardial infarction in the National Registry of Myocardial Infarction from 1990 to 2006
    William J Rogers
    University of Alabama Medical Center, Birmingham, AL 35294, USA
    Am Heart J 156:1026-34. 2008
    ..have been the focus of intense clinical investigation, limited information exists on characteristics and hospital mortality of patients not enrolled in clinical trials...
  90. ncbi The impact of weekends on outcome for acute exacerbations of COPD
    R Barba
    Depts of Internal Medicine, Hospital Infanta Cristina, Avda 9 Junio no 2, 28981, Parla, Madrid, Spain
    Eur Respir J 39:46-50. 2012
    ..Weekend admissions were associated with a significantly higher in-hospital mortality (12.9%) than weekday admissions (12.1%) among COPD patients (OR 1.07 (95% CI 1.04-1.10))...
  91. ncbi Impact of age on treatment and outcomes in ST-elevation myocardial infarction
    Marc C Newell
    Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
    Am Heart J 161:664-72. 2011
    ..We hypothesized that older patients in a regional ST-elevation myocardial infarction (STEMI) transfer program would attain comparable treatment to younger patients...
  92. ncbi An emergency department septic shock protocol and care guideline for children initiated at triage
    Gitte Y Larsen
    Pediatric Critical Care, Primary Children s Medical Center, Salt Lake City, UT 84158 0289, USA
    Pediatrics 127:e1585-92. 2011
    ..Unrecognized and undertreated septic shock increases morbidity and mortality. Septic shock in children is defined as sepsis and cardiovascular organ dysfunction, not necessarily with hypotension...
  93. pmc Comparison of hospital risk-standardized mortality rates calculated by using in-hospital and 30-day models: an observational study with implications for hospital profiling
    Elizabeth E Drye
    Yale University School of Medicine, Yale New Haven Hospital Center for Outcomes Research and Evaluation, New Haven, Connecticut 06510, USA
    Ann Intern Med 156:19-26. 2012
    In-hospital mortality measures, which are widely used to assess hospital quality, are not based on a standardized follow-up period and may systematically favor hospitals with shorter lengths of stay (LOSs).
  94. ncbi Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, USA
    JAMA 308:257-64. 2012
    ....
  95. ncbi Impact of HAART advent on admission patterns and survival in HIV-infected patients admitted to an intensive care unit
    Enrique Casalino
    Infectious Diseases Intensive Care Unit and the Epidemiology and Biostatistics Department, Bichat Claude Bernard University Hospital, Paris, France
    AIDS 18:1429-33. 2004
    ..Several studies found increased survival times and decreased hospitalization rates since the introduction of highly active antiretroviral therapy (HAART)...
  96. ncbi Comparison of men and women with acute coronary syndrome in six Middle Eastern countries
    Ayman El-Menyar
    Department of Cardiology, Hamad Medical Corporation Hospital, Doha, Qatar
    Am J Cardiol 104:1018-22. 2009
    ..not only ranked higher on Global Registry of Acute Coronary Events risk score but also had increased in-hospital mortality, 1.75 times that of men...
  97. ncbi Significant decrease in in-hospital mortality and major adverse cardiac events in Swiss STEMI patients between 2000 and December 2007
    Valérie Stolt Steiger
    Division of Cardiology, Hopital Cantonal, Fribourg, Switzerland
    Swiss Med Wkly 139:453-7. 2009
    To evaluate the in-hospital outcome of STEMI (ST elevation myocardial infarction) patients admitted to Swiss hospitals between 2000 and December 2007, and to identify the predictors of in-hospital mortality and major cardiac events.
  98. ncbi Effect of hospital volume on clinical outcome in patients with acute pancreatitis, based on a national administrative database
    Atsuhiko Murata
    Department of Preventive Medicine and Community Health, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    Pancreas 40:1018-23. 2011
    ..This study aimed to investigate the relationship between hospital volume and clinical outcome in patients with acute pancreatitis, using a Japanese national administrative database...
  99. ncbi Using hospital standardised mortality ratios to assess quality of care--proceed with extreme caution
    Ian A Scott
    Department of Internal Medicine and Clinical Epidemiology, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Med J Aust 194:645-8. 2011
    ..It may be better suited to monitoring changes in outcomes over time within individual institutions...
  100. ncbi The New Injury Severity Score: a more accurate predictor of in-hospital mortality than the Injury Severity Score
    Andre Lavoie
    Centre Hospitalier Affilie Universitaire De Quebec, Enfant Jésus Hospital, Quebec City, Quebec, Canada
    J Trauma 56:1312-20. 2004
    ....
  101. ncbi The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection
    Nathan Shapiro
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA
    Ann Emerg Med 48:583-90, 590.e1. 2006
    ....

Research Grants63

  1. C. Difficile Outcomes and Effectiveness of Treatment Strategies in SCI
    Charlesnika T Evans; Fiscal Year: 2013
    ..time, 2) recent fluoroquinolone exposure will be a significant risk factor for CDI in SCI/D veterans, 3) in-hospital mortality will be higher for SCI/D veterans with CDI diagnosis compared to those without such a diagnosis, 4) length ..
  2. Biochemical, Biomechanical & Morphological Properties of Quantitative Ultrasound
    Barbara L McFarlin; Fiscal Year: 2010
    ..Reducing the preterm birth rate to 7% in the United States is a goal of the Healthy People 2010 initiative, and it is only by reducing the incidence of preterm birth that infant mortality in the United States can be addressed. ..
  3. Perioperative Use and Outcomes of Noninvasive Ventilation in Sleep Apnea
    Peter K Lindenauer; Fiscal Year: 2013
    ..Secondary outcomes will include other respiratory and cardiovascular complications, in-hospital mortality, length of stay, and cost of hospitalization...
  4. Effectiveness of ICP Monitoring in Pediatric Traumatic Brain Injury
    TELLEN BENNETT; Fiscal Year: 2013
    ..to test the hypothesis that intracranial pressure (ICP) monitoring is associated with a lower likelihood of hospital mortality or poor functional outcome in children with severe TBI...
  5. In Silico Model for Acute Lung Injury Prediction and Clinical Trial Design
    Ognjen Gajic; Fiscal Year: 2010
    ..ARDS) are a major public health problem afflicting 200,000 patients per year and accounting for an in-hospital mortality of 40% and 3.5 million hospital-days...
  6. Novel Anti-infective and Anti-thrombotic Micro-patterned Central Venous Catheter
    SHRAVANTHI REDDY; Fiscal Year: 2012
    ..the risk of infection, CRT is associated with thromboembolic conditions that are the leading cause of in-hospital mortality in the U.S...
  7. Prospective Validation and Cost Analysis of the National Guidelines for Field Tri
    Craig D Newgard; Fiscal Year: 2011
    ..intervention, interventional radiology, ICU stay e 2 days, transfusion, prolonged ventilation or in- hospital mortality). Costs will be translated using hospital cost-to-charge ratios, plus EMS and physician costs...
  8. CEREBRAL FUNCTION AFTER HYPOTHERMIC CIRCULATORY ARREST
    Gabriele DiLuozzo; Fiscal Year: 2012
    ..centers focusing on aortic surgery, fewer than 2000 per year (10%) are treated surgically, with a nationwide hospital mortality rate of at least 20% and a one-year survival of only 60 to 70%...
  9. Determining the Effect of Chronic Ethanol Ingestion on Pulmonary Macrophages
    Sheena D Brown; Fiscal Year: 2010
    ..The outcome of alcoholic patients with ARDS is worse than in non-alcoholics, as seen by a 30% increase in in-hospital mortality rates...
  10. Urinary Biomarkers for Recovery After Acute Kidney Injury and Prognosis in Hospit
    ISAAC ELI HALL; Fiscal Year: 2010
    ..g. length of stay and in-hospital mortality) in a prospective cohort of 200 general hospitalized patients with acute kidney injury (AKI)...
  11. Efficacy and Mechanisms of GLN Dipeptide in the SICU
    Thomas R Ziegler; Fiscal Year: 2012
    ..Specific Aim 1 is to determine whether AG-PN decreases hospital mortality, nosocomial infection and other important indices of morbidity...
  12. Intrathoracic Pressure Regulation for the Treatment of Septic Shock
    Keith Lurie; Fiscal Year: 2009
    ..It has been estimated that >750,000 cases of severe sepsis occur annually in the United States, with a hospital mortality rate of ~35%. This number continues to grow annually...
  13. Patient-Centered Adherence Intervention After ACS Hospitalization
    P Michael Ho; Fiscal Year: 2013
    ..Recent advances in the treatment of acute MI have led to declines in hospital mortality. Despite this, the risk of recurrent events and mortality after the index MI hospitalization remains ..
  14. MYOCARDIAL PROTECTION: REPERFUSION INJURY AMELIORATION
    James D McCully; Fiscal Year: 2010
    ..rates than equally matched men in low-risk and medium-risk groups and significant differences in in-hospital mortality for women persist despite the fact that women have better cardiac function pre-operatively and fewer bypass ..
  15. Patient safety and outcomes in sepsis
    Vincent Liu; Fiscal Year: 2010
    ..Increasing in both incidence and severity, sepsis is also associated with extremely high in-hospital mortality rates, increased risks of death among survivors, and considerable use of healthcare resources...
  16. Pediatric Heart Network Regents of the University of Michigan
    Richard G Ohye; Fiscal Year: 2013
    ..b>Hospital mortality for the Stage I, Norwood operation has improved dramatically in recent years;the period between hospital ..
  17. Mexican Chronic Renal Insufficiency Cohort Study
    James P Lash; Fiscal Year: 2013
    ..Furthermore, CKD is the third most common cause of in-hospital mortality in Mexico. Despite the magnitude of this problem, little is known about the epidemiology of CKD in Mexico...
  18. Randomized Clinical Trial of a Less-Invasive Resuscitation Protocol for Sepsis
    Alan E Jones; Fiscal Year: 2010
    ..has suggested that fully invasive goal- directed resuscitation in the ED could substantially reduce the in-hospital mortality and hospital resources in severe sepsis and septic shock...
  19. Measuring and Mitigating Patient Safety Threats Due to Strains on ICU Capacity
    SCOTT DAVID HALPERN; Fiscal Year: 2013
    ..therapies, 2) failures to perform tests designed to diagnose adverse events, and 3) risks for in-hospital mortality following transitions of care...
  20. Statistical Methodology Development in Blood Transfusion Protocol Research
    Mohammad H Rahbar; Fiscal Year: 2013
    ..MT), defined as 10 or more units within 24 hours, consume 71% of all RBC transfusions with a 40% risk of in-hospital mortality. Plasma and platelets (separate components) are given to 90% and 71% of MT patients, respectively...
  21. Effects of publicly reporting intensive care unit outcomes
    LORA ANN REINECK; Fiscal Year: 2013
    ..gaps by taking advantage of a natural experiment in which California has been publicly reporting ICU in-hospital mortality rates since 2007, while other states have not...
  22. Development of a point of care diagnostic to guide efficient usage of blood produ
    Francesco Viola; Fiscal Year: 2013
    ..odds of severe infection by 76%, cardiac morbidity by 55%, neurological morbidity by 39%, and overall in- hospital mortality by 77%. Furthermore post-operative length of stay increases by 0.82 days per unit transfused...
  23. Referral Patterns and Risk of Early Revision after Primary Total Joint Arthroplas
    STEPHEN L LYMAN; Fiscal Year: 2010
    ..improves short-term outcomes, particularly rates of surgical complication, 90 day readmission, 90 day in-hospital mortality, and subsequent revision surgery...
  24. Renal Replacement in Acute Kidney Injury During Moderate Metabolic Disarray
    Francis Perry Wilson; Fiscal Year: 2012
    ..with these methods (censored at initiation of dialysis or development of severe disarray) on predicting in-hospital mortality. Aim 2: Assess the impact of renal replacement therapy (RRT) initiated during moderate metabolic disarray on ..
  25. Palpitations in the ED Epidemiology and Variation in Clinical Management
    Marc Probst; Fiscal Year: 2013
    ..testing (EKG, chest x-ray, cardiac enzyme), medication usage, admission patterns, discharge diagnoses and in-hospital mortality. This will be accomplished by conducting a secondary data analysis of the ED portion of the National ..
  26. Field Triage of Head Injured Older Adults Taking Anticoagulants or Platelet Inhib
    DANIEL KIDEN NISHIJIMA; Fiscal Year: 2013
    ..by the primary outcome of immediate tICH and the secondary outcomes of serious injury (Injury Severity Score greater than 15) and trauma center resource use (ICU admission, major non-orthopedic surgery, and/or in-hospital mortality).
  27. Validation of the Denver Trauma Organ Failure Score
    JODY ANN VOGEL; Fiscal Year: 2013
    ..The third hypotheses are that in-hospital mortality and intensive care resource utilization (defined by need for and duration of mechanical ventilation, ..
  28. Evaluation of Inpatient Care Teams to Improve Quality
    David H Howard; Fiscal Year: 2013
    ..We hypothesize that ACUs will reduce the incidence of in-hospital mortality and other markers for poor quality care (e.g...
  29. Exploring the role of dyssynchrony in pediatric heart disease with MRI
    Brandon K Fornwalt; Fiscal Year: 2013
    ..cost the United States an estimated $2 billion in 2006 and is increasing in prevalence and cost despite hospital mortality unfortunately remaining constant at 7%...
  30. An Evaluation of the Effectiveness and Process of a Rapid Response System
    TANYA ELISE LORD; Fiscal Year: 2010
    ..a RRS to reduce cardiac arrests on hospital medical or surgical floors, un-anticipated ICU transfers and all hospital mortality rates remains inconclusive, partly because of weak study designs and partly due to a failure of published ..
  31. The impact of pediatric trauma centers on the outcome of injured children in Ohio
    Laura D Cassidy; Fiscal Year: 2013
    ..A total of 19,187 pediatric patients, over a 5-year period, will be analyzed to evaluate in-hospital mortality, length of stay, operations and complications by relevant covariates...
  32. Contextual Factors Associated with Implementation Effectiveness within a QIColla
    Peter K Lindenauer; Fiscal Year: 2012
    ..One of the most ambitious goals of the QUEST collaborative is to reduce risk-adjusted hospital mortality rates...
  33. Pediatric Heart Network Emory University
    William T Mahle; Fiscal Year: 2013
    ..The study will focus on neonatal cardiac surgery which currently has a hospital mortality of greater than 10%...
  34. Integrated Multifunctional Imaging of Deep Vein Thrombosis
    Walter Scott; Fiscal Year: 2009
    ..pulmonary embolism (PE), is a significant clinical problem, representing the leading cause of preventable in-hospital mortality in the USA and other developed countries...
  35. Mortality Risk Adjustment with Present On Admission Diagnoses
    George J Stukenborg; Fiscal Year: 2012
    Project Summary / Abstract Hospital mortality outcomes are a focus of quality improvement programs conducted by federal and state government agencies and other organizations...
  36. Targeting Hospital-Acquired Complications: Impact on the Care of Complex Patients
    JENNIFER ANN MEDDINGS; Fiscal Year: 2013
    ..These two knowledge gaps are significant, as public reporting of other patient outcomes (e.g., hospital mortality) has demonstrated that evaluating and reporting outcome data is complicated, and can have both intended and ..
  37. Preventable Mortality in Maryland Medicaid SMI
    Gail Daumit; Fiscal Year: 2009
    ..In the SMI cohort we will then: 3) Examine the risk of in-hospital mortality or mortality within 30 days of hospital discharge associated with the occurrence of adverse events in ..
  38. Gender as a Risk Factor for Pediatric Cardiac Surgery
    Ruey Kang Chang; Fiscal Year: 2002
    ..This project will provide important information to clinicians and healthcare policymakers, and lead to future research on eliminating the gender differences in cardiovascular outcomes. ..
  39. MEDICAL OUTCOMES IN THE PRICING OF HOSPITAL PROCEDURES
    Avi Dor; Fiscal Year: 2001
    ..Hospital quality is defined in terms of medical outcomes, i.e., less-than-expected in-hospital mortality rates. We will focus on cardiac procedures such as CABG and PTCA...
  40. Hospital Care IDUs with Soft Tissue Infections
    Traci Takahashi; Fiscal Year: 2004
    ..and costs, and (3) identify hospital factors associated with increased health care utilization and in-hospital mortality among illicit drug users with soft tissue infections...
  41. ASSESSING RISK FACTORS AND HOSPITAL QUALITY FOR CABG
    Edward Hannan; Fiscal Year: 1992
    ..significantly related to the probability of a coronary artery bypass graft (CABG) patient experiencing an in-hospital mortality or perioperative complication, and (b) to use this information to assess the relative quality of care ..
  42. Comparative Evaluation of Urinary Biological Markers for the Prognostic Stratific
    Bertrand Jaber; Fiscal Year: 2009
    ..scores in predicting adverse outcomes in patients with established ARF, including dialysis requirement and hospital mortality. We will test these hypotheses in a large cohort of 300 hospitalized patients with ARF, of which over 200 ..
  43. ARDS - EDEN OMEGA Protocol
    TERRI HOUGH; Fiscal Year: 2011
    ..outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as ..
  44. Re-Exploring Racial Disparities in Hospital Care
    Jay Shen; Fiscal Year: 2002
    ..to examines the interactive effects between race and other factors on outcome that are measured by the in-hospital mortality risk...
  45. EFFECTIVENESS OF DELIRIUM PREVENTION IN ELDERLY PATIENTS
    SHARON INOUYE; Fiscal Year: 2004
    ..and potentially preventable problem for hospitalized older patients, with occurrence rates of 25-60 percent, hospital mortality rates of 25-33 percent, and annual Medicare expenditures of over $4 billion (1994)...
  46. Urinary Biomarkers for Acute Kidney Injury in Critical Illness
    Steven Coca; Fiscal Year: 2007
    ..concentrations can risk-statify patients with AKI in terms of the need for renal replacement therapy and in-hospital mortality. The results from this study will help later guide a definitive large multicenter study by developing the ..
  47. DECLINING HOSPITAL MORTALITY IN CLEVELAND: IS IT REAL
    David Baker; Fiscal Year: 2000
    Aims: Since the start of the Cleveland Health Quality Choice (CHQC) Program in 1991, in-hospital mortality for 6 key medical conditions declined 16-45 percent, and length of stay declined 24-37 percent...
  48. LUNG WATER MEASUREMENTS IN INTENSIVE CARE
    Daniel Schuster; Fiscal Year: 1990
    ..in study duration) 2) time required for mechanical ventilatory support, time in the ICU, and both ICU and hospital mortality. 3) mortality as a function of initial EVLW measurement, or as a function of change in the EVLW measurement ..
  49. Impact of Neonatal Heart Rate Characteristics Monitoring
    JOSEPH MOORMAN; Fiscal Year: 2009
    ..Secondary endpoints are length of stay, antibiotic usage, and in-hospital mortality, and we will study the supergroup of all NICU admissions...
  50. NIDDM, EXERCISE REFERRAL, & OLDER AFRICAN AMERICAN WOMEN
    Daniel Clark; Fiscal Year: 2001
    ..of developing type 2 diabetes, but experience twice the rate of nephropathy, retinopathy, amputation, and in-hospital mortality related to amputations...
  51. Tree-Structured Prediction Model for Outcomes after PCI
    Abdissa Negassa; Fiscal Year: 2007
    ..System (PCIRS) database, this study proposes to develop a tree-structured prognostic classification for in-hospital mortality, post-procedural complications and long-term survival...
  52. Mortality Risk Adjustment Using Hospital Claims Data
    George Stukenborg; Fiscal Year: 2004
    This project describes Dr. Stukenborg's plan to develop improved public domain hospital mortality prediction methods for use with administrative data, in collaboration with faculty sponsors who have substantial expertise in health care ..
  53. Measuring the Value of Romote ICU Monitoring
    Eric Thomas; Fiscal Year: 2006
    ..consultation or closed ICU where intensivists see all patients) is associated with a 29 percent reduction in hospital mortality and a 49 percent reduction in ICU mortality. However, only 10-15 percent of U.S...
  54. Regionalizing Cancer Surgery
    Vivian Ho; Fiscal Year: 2007
    ..In past research, lower competition for patients between hospitals has also been associated with both higher hospital mortality and higher costs...
  55. ARDS - EDEN Protocol
    Rolf D Hubmayr; Fiscal Year: 2009
    ..outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as ..
  56. ARDS - EDEN Protocol
    Jay Steingrub; Fiscal Year: 2009
    ..outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as ..
  57. ARDS - EDEN Protocol
    Alan H Morris; Fiscal Year: 2009
    ..outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as ..
  58. ARDS - EDEN Protocol
    Leonard Hudson; Fiscal Year: 2009
    ..outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as ..
  59. EFFECTS OF INTERN WORKLOAD ON INPATIENT MEDICAL CARE
    Steven Hillson; Fiscal Year: 1990
    ..In-hospital mortality, early readmission, nursing home placement, and rate of nosocomial infection will be the indicators of ..