prevalence

Summary

Summary: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.

Top Publications

  1. ncbi The global burden of headache: a documentation of headache prevalence and disability worldwide
    Lj Stovner
    Norwegian National Headache Centre, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Cephalalgia 27:193-210. 2007
  2. ncbi HIV infection and multidrug-resistant tuberculosis: the perfect storm
    Charles D Wells
    Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 196:S86-107. 2007
  3. doi Prevalence and trends in obesity among US adults, 1999-2008
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 303:235-41. 2010
  4. pmc A new equation to estimate glomerular filtration rate
    Andrew S Levey
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 150:604-12. 2009
  5. doi Prevalence of diabetes among men and women in China
    Wenying Yang
    China Japan Friendship Hospital, Beijing, China
    N Engl J Med 362:1090-101. 2010
  6. doi Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 307:491-7. 2012
  7. doi Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    JAMA 307:483-90. 2012
  8. ncbi Global cancer statistics, 2002
    D Max Parkin
    Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France
    CA Cancer J Clin 55:74-108. 2005
  9. doi Maternal and child undernutrition: global and regional exposures and health consequences
    Robert E Black
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 371:243-60. 2008
  10. doi Prevalence of high body mass index in US children and adolescents, 2007-2008
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 303:242-9. 2010

Detail Information

Publications332 found, 100 shown here

  1. ncbi The global burden of headache: a documentation of headache prevalence and disability worldwide
    Lj Stovner
    Norwegian National Headache Centre, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Cephalalgia 27:193-210. 2007
    ..Campaign to Reduce the Burden of Headache Worldwide', assesses and presents all existing evidence of the world prevalence and burden of headache disorders...
  2. ncbi HIV infection and multidrug-resistant tuberculosis: the perfect storm
    Charles D Wells
    Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 196:S86-107. 2007
    ..The global human immunodeficiency virus (HIV) infection epidemic has caused explosive increases in TB incidence and may be contributing to increases in MDR-TB prevalence.
  3. doi Prevalence and trends in obesity among US adults, 1999-2008
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 303:235-41. 2010
    The prevalence of obesity increased in the United States between 1976-1980 and 1988-1994 and again between 1988-1994 and 1999-2000.
  4. pmc A new equation to estimate glomerular filtration rate
    Andrew S Levey
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 150:604-12. 2009
    ..Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher values...
  5. doi Prevalence of diabetes among men and women in China
    Wenying Yang
    China Japan Friendship Hospital, Beijing, China
    N Engl J Med 362:1090-101. 2010
    Because of the rapid change in lifestyle in China, there is concern that diabetes may become epidemic. We conducted a national study from June 2007 through May 2008 to estimate the prevalence of diabetes among Chinese adults.
  6. doi Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 307:491-7. 2012
    Between 1980 and 1999, the prevalence of adult obesity (body mass index [BMI] ≥30) increased in the United States and the distribution of BMI changed. More recent data suggested a slowing or leveling off of these trends.
  7. doi Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    JAMA 307:483-90. 2012
    The prevalence of childhood obesity increased in the 1980s and 1990s but there were no significant changes in prevalence between 1999-2000 and 2007-2008 in the United States.
  8. ncbi Global cancer statistics, 2002
    D Max Parkin
    Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France
    CA Cancer J Clin 55:74-108. 2005
    Estimates of the worldwide incidence, mortality and prevalence of 26 cancers in the year 2002 are now available in the GLOBOCAN series of the International Agency for Research on Cancer...
  9. doi Maternal and child undernutrition: global and regional exposures and health consequences
    Robert E Black
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 371:243-60. 2008
  10. doi Prevalence of high body mass index in US children and adolescents, 2007-2008
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 303:242-9. 2010
    The prevalence of high body mass index (BMI) among children and adolescents in the United States appeared to plateau between 1999 and 2006.
  11. ncbi Short screening scales to monitor population prevalences and trends in non-specific psychological distress
    R C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Psychol Med 32:959-76. 2002
    ..A 10-question screening scale of psychological distress and a six-question short-form scale embedded within the 10-question scale were developed for the redesigned US National Health Interview Survey (NHIS)...
  12. pmc Global data on visual impairment in the year 2002
    Serge Resnikoff
    Programme for the Prevention of Blindness and Deafness, World Health Organization, Geneva 1211, Switzerland
    Bull World Health Organ 82:844-51. 2004
    This paper presents estimates of the prevalence of visual impairment and its causes in 2002, based on the best available evidence derived from recent studies...
  13. ncbi Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    Ali H Mokdad
    Division of Adult and Community Health, 4770 National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341 3717, USA
    JAMA 289:76-9. 2003
    ..Obesity and diabetes are increasing in the United States...
  14. pmc Prevalence of childhood and adult obesity in the United States, 2011-2012
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland
    JAMA 311:806-14. 2014
    More than one-third of adults and 17% of youth in the United States are obese, although the prevalence remained stable between 2003-2004 and 2009-2010.
  15. doi IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030
    David R Whiting
    International Diabetes Federation, Brussels, Belgium
    Diabetes Res Clin Pract 94:311-21. 2011
    Diabetes is an increasingly important condition globally and robust estimates of its prevalence are required for allocating resources.
  16. ncbi Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections
    H King
    Division of Noncommunicable Diseases, World Health Organization, Geneva, Switzerland
    Diabetes Care 21:1414-31. 1998
    To estimate the prevalence of diabetes and the number of people with diabetes who are > or =20 years of age in all countries of the world for three points in time, i.e...
  17. ncbi Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
    J M Walboomers
    Department of Pathology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands
    J Pathol 189:12-9. 1999
    ..001). Combining the data from this and the previous study and excluding inadequate specimens, the worldwide HPV prevalence in cervical carcinomas is 99.7 per cent...
  18. ncbi Vitamin D deficiency
    Michael F Holick
    Department of Medicine, Section of Endocrinology, Nutrition, and Diabetes, the Vitamin D, Skin, and Bone Research Laboratory, Boston University Medical Center, Boston, MA 02118, USA
    N Engl J Med 357:266-81. 2007
  19. pmc The number of people with glaucoma worldwide in 2010 and 2020
    H A Quigley
    The Glaucoma Service and the Dana Center for Preventive Opthalmalogy, Wilmer Opthalmological Institute, Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Br J Ophthalmol 90:262-7. 2006
    ..To estimate the number of people with open angle (OAG) and angle closure glaucoma (ACG) in 2010 and 2020...
  20. doi National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
    Goodarz Danaei
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Lancet 378:31-40. 2011
    Data for trends in glycaemia and diabetes prevalence are needed to understand the effects of diet and lifestyle within populations, assess the performance of interventions, and plan health services...
  21. ncbi Depression, chronic diseases, and decrements in health: results from the World Health Surveys
    Saba Moussavi
    Department of Measurement and Health Information Systems, World Health Organization, Geneva, Switzerland
    Lancet 370:851-8. 2007
    ..Depression is often comorbid with other chronic diseases and can worsen their associated health outcomes. Few studies have explored the effect of depression, alone or as a comorbidity, on overall health status...
  22. ncbi Worldwide trends in childhood overweight and obesity
    Youfa Wang
    Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Int J Pediatr Obes 1:11-25. 2006
    ..This paper summarises the available information on recent trends in child overweight and obesity prevalence.
  23. ncbi The global burden of asthma: executive summary of the GINA Dissemination Committee report
    Matthew Masoli
    Allergy 59:469-78. 2004
  24. doi Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model
    Reuben M Granich
    Department of HIV AIDS, WHO, Geneva, Switzerland
    Lancet 373:48-57. 2009
    ..We investigated a theoretical strategy of universal voluntary HIV testing and immediate treatment with ART, and examined the conditions under which the HIV epidemic could be driven towards elimination...
  25. pmc A world malaria map: Plasmodium falciparum endemicity in 2007
    Simon I Hay
    Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute University of Oxford Wellcome TrustCollaborative Programme, Nairobi, Kenya
    PLoS Med 6:e1000048. 2009
    ..It is exactly 40 y since the last global map of malaria endemicity was published. This paper describes the generation of a new world map of Plasmodium falciparum malaria endemicity for the year 2007...
  26. ncbi Cardiovascular morbidity and mortality associated with the metabolic syndrome
    B Isomaa
    Department of Internal Medicine, Jakobstad Hospital, Finland
    Diabetes Care 24:683-9. 2001
    To estimate the prevalence of and the cardiovascular risk associated with the metabolic syndrome using the new definition proposed by the World Health Organization
  27. ncbi Prevalence of chronic kidney disease in the United States
    Josef Coresh
    Department of Epidemiology, Bloomberg School of Public Health, and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland 21287, USA
    JAMA 298:2038-47. 2007
    The prevalence and incidence of kidney failure treated by dialysis and transplantation in the United States have increased from 1988 to 2004...
  28. pmc Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Gen Psychiatry 62:617-27. 2005
    Little is known about the general population prevalence or severity of DSM-IV mental disorders.
  29. ncbi Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
    Sarah Wild
    Public Health Sciences, University of Edinburgh, Edinburgh, Scotland
    Diabetes Care 27:1047-53. 2004
    The goal of this study was to estimate the prevalence of diabetes and the number of people of all ages with diabetes for years 2000 and 2030.
  30. ncbi The obesity epidemic in the United States--gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis
    Youfa Wang
    Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Epidemiol Rev 29:6-28. 2007
    ..Average annual increase in and future projections for prevalence were estimated by using linear regression models...
  31. doi US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, 135 Rutledge Ave, 1230 RT, Charleston, SC 29425, USA
    JAMA 303:2043-50. 2010
    ..Hypertension is a major risk factor for cardiovascular disease and treatment and control of hypertension reduces risk. The Healthy People 2010 goal was to achieve blood pressure (BP) control in 50% of the US population...
  32. ncbi The growing burden of tuberculosis: global trends and interactions with the HIV epidemic
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England, UK
    Arch Intern Med 163:1009-21. 2003
    ..The increasing global burden of tuberculosis (TB) is linked to human immunodeficiency virus (HIV) infection...
  33. pmc The projected effect of risk factor reduction on Alzheimer's disease prevalence
    Deborah E Barnes
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94121, USA
    Lancet Neurol 10:819-28. 2011
    At present, about 33·9 million people worldwide have Alzheimer's disease (AD), and prevalence is expected to triple over the next 40 years...
  34. ncbi Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    Mark J Sarnak
    Circulation 108:2154-69. 2003
  35. ncbi Global burden of hypertension: analysis of worldwide data
    Patricia M Kearney
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
    Lancet 365:217-23. 2005
    Reliable information about the prevalence of hypertension in different world regions is essential to the development of national and international health policies for prevention and control of this condition...
  36. doi Global estimates of cancer prevalence for 27 sites in the adult population in 2008
    Freddie Bray
    Section of Cancer Information, International Agency for Research on Cancer, Lyon, France
    Int J Cancer 132:1133-45. 2013
    Recent estimates of global cancer incidence and survival were used to update previous figures of limited duration prevalence to the year 2008...
  37. doi Global estimates of the prevalence of diabetes for 2010 and 2030
    J E Shaw
    Epidemiology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Res Clin Pract 87:4-14. 2010
    ..We estimated the number of people worldwide with diabetes for the years 2010 and 2030...
  38. ncbi Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    Klaus F Rabe
    Leiden University Medical Center, Pulmonology, P O Box 9600, NL 2300 RC, Leiden, The Netherlands
    Am J Respir Crit Care Med 176:532-55. 2007
    ..GOLD national leaders, a network of international experts, have initiated investigations of the causes and prevalence of COPD in their countries, and developed innovative approaches for the dissemination and implementation of COPD ..
  39. ncbi The global health burden of infection-associated cancers in the year 2002
    Donald Maxwell Parkin
    Clinical Trials Service Unit and Epidemiological Studies Unit, University of Oxford, Headington, UK
    Int J Cancer 118:3030-44. 2006
    ..several methods; primarily by reviewing the evidence for the strength of the association (relative risk) and the prevalence of infection in different world areas...
  40. ncbi Screening for serious mental illness in the general population
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Suite 215, Boston, MA 02115, USA
    Arch Gen Psychiatry 60:184-9. 2003
    Public Law 102-321 established a block grant for adults with "serious mental illness" (SMI) and required the Substance Abuse and Mental Health Services Administration (SAMHSA) to develop a method to estimate the prevalence of SMI.
  41. ncbi Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys
    M Innes Asher
    Department of Paediatrics, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1010, New Zealand
    Lancet 368:733-43. 2006
    Data for trends in prevalence of asthma, allergic rhinoconjunctivitis, and eczema over time are scarce...
  42. pmc Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II
    Reva C Lawrence
    NIH, Bethesda, Maryland, USA
    Arthritis Rheum 58:26-35. 2008
    To provide a single source for the best available estimates of the US prevalence of and number of individuals affected by osteoarthritis, polymyalgia rheumatica and giant cell arteritis, gout, fibromyalgia, and carpal tunnel syndrome, as ..
  43. ncbi Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    Earl S Ford
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E 17, Atlanta, GA 30333
    JAMA 287:356-9. 2002
    ..Limited information is available about the prevalence of the metabolic syndrome in the United States, however.
  44. ncbi Global patterns of influenza a virus in wild birds
    Bjorn Olsen
    Department of Infectious Diseases, Umea University, SE 90187 Umea, Sweden
    Science 312:384-8. 2006
    ....
  45. ncbi The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    JAMA 289:3095-105. 2003
    Uncertainties exist about prevalence and correlates of major depressive disorder (MDD).
  46. ncbi Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial
    Robert C Bailey
    Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, IL 60612, USA
    Lancet 369:643-56. 2007
    ..Our aim was to determine whether male circumcision had a protective effect against HIV infection, and to assess safety and changes in sexual behaviour related to this intervention...
  47. ncbi Global and societal implications of the diabetes epidemic
    P Zimmet
    International Diabetes Institute, 260 Kooyong Road, Caulfield, Victoria 3162, Australia
    Nature 414:782-7. 2001
    ..The prevention of diabetes and control of its micro- and macrovascular complications will require an integrated, international approach if we are to see significant reduction in the huge premature morbidity and mortality it causes...
  48. pmc G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map
    Rosalind E Howes
    Spatial Ecology and Epidemiology Group, Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS Med 9:e1001339. 2012
    ..We present a continuous evidence-based prevalence map of G6PDd and estimates of affected populations, together with a national index of relative haemolytic risk.
  49. ncbi Multi-Ethnic Study of Atherosclerosis: objectives and design
    Diane E Bild
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Am J Epidemiol 156:871-81. 2002
    The Multi-Ethnic Study of Atherosclerosis was initiated in July 2000 to investigate the prevalence, correlates, and progression of subclinical cardiovascular disease (CVD) in a population-based sample of 6,500 men and women aged 45-84 ..
  50. ncbi Trends in prevalence and outcome of heart failure with preserved ejection fraction
    Theophilus E Owan
    Cardiorenal Research Laboratory, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    N Engl J Med 355:251-9. 2006
    The prevalence of heart failure with preserved ejection fraction may be changing as a result of changes in population demographics and in the prevalence and treatment of risk factors for heart failure...
  51. pmc A commentary on studies presenting projections of the future prevalence of dementia
    Sam Norton
    Institute of Public Health, University of Cambridge, Cambridge, UK
    BMC Public Health 13:1. 2013
    Population ageing over the first half of this century is likely to lead to dramatic increases in the prevalence of dementia. This will affect all regions of the world, but particularly developing regions...
  52. ncbi Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    Giulio Marchesini
    Unit of Metabolic Diseases and Department of Internal Medicine, Alma Mater Studiorum University of Bologna, Bologna, Italy
    Hepatology 37:917-23. 2003
    ..We assessed the prevalence of the metabolic syndrome in 304 consecutive NAFLD patients without overt diabetes, on the basis of 3 or more ..
  53. ncbi The worldwide prevalence of ADHD: a systematic review and metaregression analysis
    Guilherme Polanczyk
    ADHD Outpatient Program, Child and Adolescent Psychiatric Division, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil 90035 003
    Am J Psychiatry 164:942-8. 2007
    The worldwide prevalence estimates of attention deficit hyperactivity disorder (ADHD)/hyperkinetic disorder (HD) are highly heterogeneous. Presently, the reasons for this discrepancy remain poorly understood...
  54. doi Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    Jurgen Rehm
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Lancet 373:2223-33. 2009
    ..We assess alcohol exposure and prevalence of alcohol-use disorders on the basis of reviews of published work...
  55. ncbi Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
    A S Go
    Division of Research, Kaiser Permanente of Northern California, 3505 Broadway, 12th Floor, Oakland, CA 94611, USA
    JAMA 285:2370-5. 2001
    Atrial fibrillation is the most common arrhythmia in elderly persons and a potent risk factor for stroke. However, recent prevalence and projected future numbers of persons with atrial fibrillation are not well described.
  56. pmc Body mass index cut offs to define thinness in children and adolescents: international survey
    Tim J Cole
    Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London WC1N 1EH
    BMJ 335:194. 2007
    ..To determine cut offs to define thinness in children and adolescents, based on body mass index at age 18 years...
  57. ncbi WHO analysis of causes of maternal death: a systematic review
    Khalid S Khan
    Academic Department of Obstetrics and Gynaecology, University of Birmingham, Birmingham, UK
    Lancet 367:1066-74. 2006
    ..Evidence-based health policies and programmes aiming to reduce maternal deaths need reliable and valid information. We undertook a systematic review to determine the distribution of causes of maternal deaths...
  58. doi Prevalence and control of diabetes in Chinese adults
    Yu Xu
    Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, E Institute of Shanghai Universities, Shanghai, China
    JAMA 310:948-59. 2013
    ..Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide...
  59. doi International study of the prevalence and outcomes of infection in intensive care units
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    JAMA 302:2323-9. 2009
    ..Infection is a major cause of morbidity and mortality in intensive care units (ICUs) worldwide. However, relatively little information is available about the global epidemiology of such infections...
  60. pmc Epidemiology and etiology of childhood pneumonia
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
    Bull World Health Organ 86:408-16. 2008
    ..Although based on limited available evidence, recent studies have identified Streptococcus pneumoniae, Haemophilus influenzae and respiratory syncytial virus as the main pathogens associated with childhood pneumonia...
  61. ncbi An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    O Johnell
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 17:1726-33. 2006
    ..The aim of this study was to quantify the global burden of osteoporotic fracture worldwide...
  62. doi HIV prevalence in China: integration of surveillance data and a systematic review
    Lei Zhang
    The Kirby Institute, University of New South Wales, Sydney, NSW, Australia Comprehensive AIDS Research Center, Tsinghua University, Beijing, China Electronic address
    Lancet Infect Dis 13:955-63. 2013
    ..We aimed to understand the complexity of HIV epidemics in China by systematically analysing prevalence trends by data source, region, population group, and time period.
  63. ncbi Frailty in older adults: evidence for a phenotype
    L P Fried
    Center on Aging and Health, The John Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Gerontol A Biol Sci Med Sci 56:M146-56. 2001
    ..A standardized definition has not yet been established...
  64. doi Submicroscopic infection in Plasmodium falciparum-endemic populations: a systematic review and meta-analysis
    Lucy C Okell
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    J Infect Dis 200:1509-17. 2009
    ..Quantifying these submicroscopic infections is therefore key to understanding transmission dynamics and successfully reducing parasite transmission...
  65. pmc The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Am J Psychiatry 163:716-23. 2006
    Despite growing interest in adult attention deficit hyperactivity disorder (ADHD), little is known about its prevalence or correlates.
  66. pmc Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio
    Aluisio J D Barros
    Programa de Pós Graduação em Epidemiologia, Universidade Federal de Pelotas, Brazil
    BMC Med Res Methodol 3:21. 2003
    ..However, the odds ratio can importantly overestimate the prevalence ratio, the measure of choice in these studies...
  67. ncbi Nonalcoholic fatty liver disease
    Paul Angulo
    Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, Minn 55905, USA
    N Engl J Med 346:1221-31. 2002
  68. ncbi Health consequences of intimate partner violence
    Jacquelyn C Campbell
    Johns Hopkins University School of Nursing, 525 North Wolfe Street, Baltimore, MD 21205 2110, USA
    Lancet 359:1331-6. 2002
    ..I recommend increased assessment and interventions for intimate partner violence in health-care settings...
  69. doi The levelling off of the obesity epidemic since the year 1999--a review of evidence and perspectives
    B Rokholm
    Institute of Preventive Medicine, Copenhagen University Hospital, Denmark
    Obes Rev 11:835-46. 2010
    ..Eligible studies and data sources were required to have at least two measures of obesity prevalence since 1999. A literature and Internet search resulted in 52 studies from 25 different countries...
  70. ncbi The metabolic syndrome in children and adolescents - an IDF consensus report
    Paul Zimmet
    International Diabetes Institute, Melbourne, Victoria, Australia
    Pediatr Diabetes 8:299-306. 2007
  71. ncbi The asthma epidemic
    Waltraud Eder
    University Children s Hospital, Munich, Germany
    N Engl J Med 355:2226-35. 2006
  72. doi Global prevalence and trends of overweight and obesity among preschool children
    Mercedes de Onis
    Growth Assessment and Surveillance Unit, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland
    Am J Clin Nutr 92:1257-64. 2010
    ..Childhood obesity is associated with serious health problems and the risk of premature illness and death later in life. Monitoring related trends is important...
  73. ncbi Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys
    Koen Demyttenaere
    JAMA 291:2581-90. 2004
    ..Little is known about the extent or severity of untreated mental disorders, especially in less-developed countries...
  74. ncbi Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa
    Marieke J van der Werf
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Acta Trop 86:125-39. 2003
    ..4 million and hepatomegaly in 8.5 million. As the associations between prevalence of S...
  75. ncbi Epidemiologic classification of human papillomavirus types associated with cervical cancer
    Nubia Munoz
    International Agency for Research on Cancer, Lyons, France
    N Engl J Med 348:518-27. 2003
    ..Infection with human papilloma virus (HPV) is the main cause of cervical cancer, but the risk associated with the various HPV types has not been adequately assessed...
  76. doi Diabetes in sub-Saharan Africa
    Jean Claude N Mbanya
    Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
    Lancet 375:2254-66. 2010
    In Sub-Saharan Africa, prevalence and burden of type 2 diabetes are rising quickly. Rapid uncontrolled urbanisation and major changes in lifestyle could be driving this epidemic...
  77. doi A systematic review of the global prevalence of low back pain
    Damian Hoy
    University of Queensland, Herston, Queensland, Australia
    Arthritis Rheum 64:2028-37. 2012
    To perform a systematic review of the global prevalence of low back pain, and to examine the influence that case definition, prevalence period, and other variables have on prevalence.
  78. ncbi International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study
    A Sonia Buist
    Oregon Health and Sciences University, Portland, OR 97239, USA
    Lancet 370:741-50. 2007
    ..pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide, and accurate estimates of the prevalence of this disease are needed to anticipate the future burden of COPD, target key risk factors, and plan for ..
  79. pmc Burden of major musculoskeletal conditions
    Anthony D Woolf
    Peninsula Medical School, Duke of Cornwall Department of Rheumatology, Royal Cornwall Hospital, Truro TR1 3LJ, England
    Bull World Health Organ 81:646-56. 2003
    ..decline, but the increase in the number of older people in some regions makes it difficult to estimate future prevalence. Osteoporosis, which is characterized by low bone mass and microarchitectural deterioration, is a major risk ..
  80. pmc HIV and syphilis prevalence among men who have sex with men: a cross-sectional survey of 61 cities in China
    Zunyou Wu
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention
    Clin Infect Dis 57:298-309. 2013
    ..We sought to test 3 hypotheses: (1) The prevalence of both HIV and syphilis among MSM in China is high, (2) the 2 epidemics each have unique geographical ..
  81. ncbi ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Sur
    Alan T Hirsch
    Circulation 113:e463-654. 2006
  82. ncbi Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994
    Stephen Cook
    Strong Children s Research Center, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Arch Pediatr Adolesc Med 157:821-7. 2003
    In adults the metabolic syndrome imposes a substantial risk for type 2 diabetes mellitus and premature coronary heart disease. Even so, no national estimate is currently available of the prevalence of this syndrome in adolescents.
  83. ncbi Global burden of COPD: systematic review and meta-analysis
    R J Halbert
    Center Life Sciences, Beverly Hills, CA 90212, USA
    Eur Respir J 28:523-32. 2006
    The aim of this study was to quantify the global prevalence of chronic obstructive pulmonary disease (COPD) by means of a systematic review and random effects meta-analysis...
  84. ncbi Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    Jeffrey D Browning
    Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9046, USA
    Hepatology 40:1387-95. 2004
    Despite the increasing prevalence of nonalcoholic fatty liver disease (NAFLD), its pathogenesis and clinical significance remain poorly defined...
  85. doi Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findings
    Laia Bruni
    Unit of Infections and Cancer, Cancer Epidemiology Research Program, IDIBELL Institut Català d Oncologia, Barcelona, Spain
    J Infect Dis 202:1789-99. 2010
    Baseline information on human papillomavirus (HPV) prevalence and type distribution is highly desirable to evaluate the impact of prophylactic HPV vaccines in the near future.
  86. doi Assessment of baseline age-specific antibody prevalence and incidence of infection to novel influenza A/H1N1 2009
    P Hardelid
    Centre for Infections, Health Protection Agency, London, UK
    Health Technol Assess 14:115-92. 2010
    The objectives of the H1N1 2009 serological surveillance project were twofold: to document (1) the prevalence of cross-reactive antibodies to H1N1 2009 by age group in the population of England prior to arrival of the pandemic strain ..
  87. ncbi Global burden of COPD: risk factors, prevalence, and future trends
    David M Mannino
    Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health, Lexington, KY 40536, USA
    Lancet 370:765-73. 2007
    ..As the global population ages, the burden of COPD will increase in years to come. Prevalence estimates of the disorder show considerable variability across populations, suggesting that risk factors can ..
  88. doi Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study
    Jean Francois Trape
    Research Unit on Emerging Infectious and Tropical Diseases, Institut de Recherche pour le Developpement, Dakar, Senegal
    Lancet Infect Dis 11:925-32. 2011
    ..Our aim was to assess the effect of these policies on malaria morbidity, mosquito populations, and asymptomatic infections in a west African rural population...
  89. doi Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
    Natalie A Molodecky
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Gastroenterology 142:46-54.e42; quiz e30. 2012
    We conducted a systematic review to determine changes in the worldwide incidence and prevalence of ulcerative colitis (UC) and Crohn's disease (CD) in different regions and with time.
  90. ncbi Causes and prevalence of visual impairment among adults in the United States
    Nathan Congdon
    Wilmer Eye Institute, Wilmer 120, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Arch Ophthalmol 122:477-85. 2004
    To estimate the cause-specific prevalence and distribution of blindness and low vision in the United States by age, race/ethnicity, and gender, and to estimate the change in these prevalence figures over the next 20 years.
  91. ncbi Prevalence of intimate partner violence: findings from the WHO multi-country study on women's health and domestic violence
    Claudia Garcia-Moreno
    WHO, Geneva, Switzerland
    Lancet 368:1260-9. 2006
    ....
  92. ncbi Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment
    Harald Breivik
    University of Oslo, Faculty of Medicine, Faculty Division Rikshospitalet, Department of Anaesthesiology, Rikshospitalet University Hospital, Norway
    Eur J Pain 10:287-333. 2006
    This large scale computer-assisted telephone survey was undertaken to explore the prevalence, severity, treatment and impact of chronic pain in 15 European countries and Israel...
  93. ncbi The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    Joseph F Perz
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of Viral Hepatitis, Epidemiology Branch, Atlanta, GA 30333, USA
    J Hepatol 45:529-38. 2006
    ..Chronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) are well-recognized risk factors for cirrhosis and liver cancer, but estimates of their contributions to worldwide disease burden have been lacking...
  94. doi Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity
    T J Cole
    MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health, London, UK
    Pediatr Obes 7:284-94. 2012
    ..International Obesity Task Force; IOTF) body mass index (BMI) cut-offs are widely used to assess the prevalence of child overweight, obesity and thinness...
  95. doi Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis
    Stefan Baral
    Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
    Lancet Infect Dis 12:538-49. 2012
    ..However, three decades into the HIV pandemic, understanding of the burden of HIV among these women remains limited. We aimed to assess the burden of HIV in this population compared with that of other women of reproductive age...
  96. ncbi Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Gen Psychiatry 62:593-602. 2005
    Little is known about lifetime prevalence or age of onset of DSM-IV disorders.
  97. ncbi The kappa statistic in reliability studies: use, interpretation, and sample size requirements
    Julius Sim
    Primary Care Sciences Research Centre, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom
    Phys Ther 85:257-68. 2005
    ..This article examines and illustrates the use and interpretation of the kappa statistic in musculoskeletal research...
  98. doi Obesity and the metabolic syndrome in developing countries
    Anoop Misra
    Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi 110070, India
    J Clin Endocrinol Metab 93:S9-30. 2008
    b>Prevalence of obesity and the metabolic syndrome is rapidly increasing in developing countries, leading to increased morbidity and mortality due to type 2 diabetes mellitus (T2DM) and cardiovascular disease.
  99. ncbi Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    Farin Kamangar
    Nutritional Epidemiology and Biostatistics Branches, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7244, USA
    J Clin Oncol 24:2137-50. 2006
    ..global cancer disparities begin with an understanding of geographic patterns in cancer incidence, mortality, and prevalence. Using the GLOBOCAN (2002) and Cancer Incidence in Five Continents databases, we describe overall cancer ..
  100. pmc Estimates of the prevalence of pandemic (H1N1) 2009, United States, April-July 2009
    Carrie Reed
    Influenza Division, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop A32, Atlanta, GA 30033, USA
    Emerg Infect Dis 15:2004-7. 2009
    ..Correcting for under-ascertainment using a multiplier model, we estimate that 1.8 million-5.7 million cases occurred, including 9,000-21,000 hospitalizations...
  101. doi Prevalence and characteristics of tinnitus among US adults
    Josef Shargorodsky
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Mass, USA
    Am J Med 123:711-8. 2010
    ..Tinnitus is common; however, few risk factors for tinnitus are known...

Research Grants132 found, 100 shown here

  1. A Phase II Trial of Levodopa in Angelman Syndrome
    Wen Hann Tan; Fiscal Year: 2013
    ..and movement disorders in children with Angelman Syndrome (AS), a rare neurodevelopmental disorder with a prevalence of approximately 1 in 10,000 to 1 in 20,000 individuals...
  2. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  3. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..The prevalence of cancer of the kidney and renal pelvis is 296,074, with 61.3% localized or 181493 patients...
  4. Cardiovascular Responses to Sleep Apnea in Tetraplegia: A Pilot Study
    Jill M Wecht; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Screening studies suggest that the prevalence of moderate to severe obstructive sleep apnea (OSA) in persons with tetraplegia ranges from 22% to 36%, thus greatly exceeding prevalence estimates of 9...
  5. Iron-mediated vascular disease in sickle cell disease.
    John C Wood; Fiscal Year: 2010
    ..In fact, no study has examined the prevalence of iron overload in SCD adults by direct measurement of total body or tissue iron...
  6. Correction of glutathione deficiency for treatment of diabetic nephropathy
    Paolo Fanti; Fiscal Year: 2013
    ..Veterans have high prevalence of T2DM, diabetic kidney disease, and associated OS...
  7. Exercise training and blood pressure in hypertension: integrated mechanisms
    Noreen F Rossi; Fiscal Year: 2012
    ..While essential hypertension is most common, the prevalence of atherosclerotic renovascular hypertension is rising with prevalence as high as 50% in high risk patients who ..
  8. Pharmacogenetics of obesity and endocannabinergic modulation (POEM)
    Russell A Wilke; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: The current obesity epidemic represents a major international health crisis. The prevalence of obesity-related medical problems is continuing to increase, placing an unprecedented burden on health care ..
  9. Brain mast cells and Chronic Fatigue Syndrome
    Theoharis C Theoharides; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Chronic Fatigue Syndrome (CFS) is a complex disease with a prevalence as high as 1%...
  10. Autonomic, Endothelial, and Inflammatory Correlates of Sleep Duration
    MERCEDES RENEE CARNETHON; Fiscal Year: 2012
    Short sleep duration (<6 hours/night) is associated with a higher prevalence and incidence of hypertension, diabetes, and overweight/obesity, all of which can contribute to coronary heart disease...
  11. Principles of Therapy in Cerebellar Disease: Explorations in Ion Channel Mutants
    JOHN SAMUEL STAHL; Fiscal Year: 2013
    ..The high prevalence arises because there are so many causes of cerebellar dysfunction, and because they are generally compatible ..
  12. Effective treatment of sleep apnea in prediabetes to reduce cardiometabolic risk
    Esra Tasali; Fiscal Year: 2010
    ..analysis of over 2500 non- diabetic individuals, the presence of OSA was associated with a significantly higher prevalence of prediabetes and incident diabetes, independently of obesity...
  13. Tyrosine Availability Influences Mesocortico-Limbic Catecholamines
    GEORGE EUGENE JASKIW; Fiscal Year: 2012
    ..There are several reasons why this might be so. The veteran population is predominantly male and has a high prevalence of psychiatric co-morbidity...
  14. Targeting Galectin-3 with novel drugs for treatment of eczema
    Fu Tong Liu; Fiscal Year: 2010
    Eczema affects a wide population age group, and prevalence of the disease has increased two- to three-fold during the past three decades in industrialized countries, where the current incidence in children is estimated to be 15-20%...
  15. Development of a Nonpsychotropic Cannabinoid Agonist for the Treatment of Sclerod
    Robert B Zurier; Fiscal Year: 2012
    ..Available data, while variable, indicate an incidence in the United States of 9 t 19 cases /million/year, and prevalence rates ranging from 28 to 253 cases/million (2). Current therapy is limited, with 10 year survival of 55%...
  16. Retinoid and Carotenoid Depletion in Patients at High-Risk for Liver Cancer
    Peter H Gann; Fiscal Year: 2010
    ..A and carotenoid stores in high-risk patients can be designed, we need exploratory studies to: a) determine the prevalence and determinants of retinoid-carotenoid depletion in well-characterized subgroups of patients typically seen in ..
  17. Natural History and Prevention of Viral Hepatitis Among Alaska Natives
    BRIAN JAMES MCMAHON; Fiscal Year: 2013
    ..strategies for infants, children, adolescents and adults have significantly decreased the incidence and prevalence of acute and chronic hepatitis B infection...
  18. Pathogenesis and Treatment of Liver Disease in Transaldolase Deficiency
    Andras Perl; Fiscal Year: 2013
    ..We also found an increased prevalence of TAL haploinsufficiency in human livers with cirrhosis and HCC...
  19. Reactive (AA)Amyloidosis
    Merrill D Benson; Fiscal Year: 2013
    ..The Veteran population also has an increase in prevalence of the age related amyloidoses including immunoglobulin amyloid, Alzheimer disease and senile cardiac ..
  20. Ang II and Overnutrition and Insulin resistance in Cardiovascular Tissue
    JAMES RUSSELL SOWERS; Fiscal Year: 2013
    ..especially that characterized by excess intake of fat and carbohydrates) is a major factor in the increased prevalence of hypertension and diabetes...
  21. Impact of the P479L Variant in CPT1A on Infant Mortality in Alaska
    David M Koeller; Fiscal Year: 2011
    ..1436C?T sequence variant, and an additional 34% are heterozygous. The high prevalence of this sequence variant has led to the speculation that it may be a benign polymorphism...
  22. Regulation of mural cells during pulmonary capillary formation
    Stephen E McGowan; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: PROJECT NARRATIVE: Although the prevalence of smoking has declined, chronic obstructive pulmonary disease (COPD) and its attendant pathological pulmonary ..
  23. METABOLIC SYNDROME AND PERIODONTITIS IN POSTMENOPAUSAL WOMEN
    Michael J LaMonte; Fiscal Year: 2013
    ..existing prospective data to examine associations of Metsyn, physical activity and body habitus with measures of prevalence and progression of periodontal disease in a cohort of postmenopausal women...
  24. Patient-Derived Stem Cells for Phosphoproteomic Profiling Neuropsychopathology
    Dieter A Wolf; Fiscal Year: 2011
    ..A major impediment to proper diagnosis has been such confounders as the prevalence of substance &alcohol abuse/dependence among those meeting criteria for BPD...
  25. Genetic and physiological causes of inherited Vascular and Metabolic Diseases
    Arya Mani; Fiscal Year: 2013
    ..In addition, to explore the prevalence and spectrum of LRP6 mutations in patients with metabolic syndrome and CAD, a cohort of 200 cases with early ..
  26. Statin modulation of immunotherapy for Alzheimer disease
    Jun Tan; Fiscal Year: 2012
    ..The frequency doubles every five years after age 60, increasing from a prevalence of about 1% in individuals aged 60 years to about 40% among those aged 85 years or greater...
  27. Mechanism of Bladder Overactivity in Pelvic Ischemia
    Kazem M Azadzoi; Fiscal Year: 2013
    ..The incidence of bladder overactivity and LUTS increases with age. Clinical studies suggest that the prevalence of bladder overactivity and LUTS among Veterans is almost five fold higher than its incidence in the general ..
  28. Epigenetics of Sex Differences in Brain and Behavior
    BRIDGET NUGENT; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: The pervasiveness of strong gender biases in the prevalence and intensity of mental health and neurological disorders highlights the importance of understanding the ..
  29. Tat and CDK9 on gene expression alterations coupled to HIV-1 Associated Dementia
    Xavier Grana; Fiscal Year: 2010
    ..Also, increased survival rates resulting from HAART have led to an increase in the prevalence of neurological disorders...
  30. Cellular &Molecular Defects in Human B Cell Development
    Charlotte Cunningham-Rundles; Fiscal Year: 2013
    ..variable immune deficiency (CVID) is the clinically most important primary antibody deficiency disease due to prevalence, complications, hospitalizations and requirement for lifelong immune globulin therapy...
  31. Role of CD44 in experimental Multiple Sclerosis
    Mitzi Nagarkatti; Fiscal Year: 2013
    ..There are over 28,000 veterans currently diagnosed with MS. Due to its high prevalence, in 2003, the Veterans Health Administration (VHA) established the MS Centers of Excellence which are committed ..
  32. Maternal obesity depresses essential fatty acid transport in the placenta
    PERRIE F O'TIERNEY-GINN; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: The prevalence of obesity in women who give birth in the US is 1 in 5, which is associated with severe health consequences for ..
  33. Combination drug treatment to inhibit multiple cell death pathways after TBI
    ALAN IRA FADEN; Fiscal Year: 2010
    ..A disability prevalence of 37% has been reported for TBI patients followed more than one year after hospitalization;based on this figure,..
  34. Nicotinic Acetylcholine Receptor Density and Veteran Cigarette Smokers
    Arthur Brody; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Despite improvements in tobacco control, the prevalence of cigarette smoking remains high at 27% among Veterans and 21% among the general U.S. population (~46 million U.S. adults)...
  35. Latin American Center for Malaria Research and Control
    SOCRATES HERRERA VALENCIA; Fiscal Year: 2013
    ..The studies proposed for aim 1 are directed to determine the real prevalence and incidence of malaria by considering both symptomatic and asymptomatic individuals living in seasonal areas ..
  36. Central Action of Brain-Derived Neurotrophic Factor in Male and Female Rats
    Haifei Shi; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: As the prevalence of overweight and obesity is rising, the incidence of type 2 diabetes, cardiovascular disease, and some types of ..
  37. Human neutrophils, phospholipase A2 and S.aureus: microbial targets and responses
    William M Nauseef; Fiscal Year: 2013
    ..According to a VA-based study, the prevalence of SA infections increased from 26.93 per 1,000 discharges in 2000 to 30.59 in 2007 ( 14%)...
  38. Parathyroid Hormone & Vitamin D Effects on Salt Sensitivity and Vascular Function
    ANNA LIZA BELEN VALINA TOTH; Fiscal Year: 2010
    ..The prevalence of elevated parathyroid hormone (PTH), typically a consequence of depressed vitamin D levels and/or low calcium ..
  39. Molecular mechanisms of lung disease in ataxia telangiectasia
    JoAnn M Sekiguchi; Fiscal Year: 2013
    ..Despite the prevalence of ILD as a cause of death in A-T patients, the underlying mechanisms that lead to this phenotype are not well ..
  40. Adenosine and the Basal Forebrain in the Control of Behavioral State
    Robert E Strecker; Fiscal Year: 2012
    ..daytime sleepiness and difficulty maintaining alertness are very common medical complaints, with even greater prevalence in older males, such as the population of US veterans...
  41. Efficacy of Yoga for Treatment-Resistant PTSD
    Bessel Van der Kolk; Fiscal Year: 2010
    ..1 Saper, R.B., Eisenberg, D.M., Davis, R.B., Culpepper, L., Phillips, R.S., 2004. Prevalence and patterns of adult yoga use in the United States: results of a national survey. Altern. Ther. Health Med...
  42. INTERNET ENHANCED HEALTH PROMOTION FOR OBESE ETHNIC MINORITY ADOLESCENTS
    Jessica A Whiteley; Fiscal Year: 2011
    A.1. Overview. The prevalence of childhood and adolescent obesity is increasing at alarming rates. The prevalence of overweight among adolescents aged 12 to 19 has tripled between 1980 and 2004 (Ogden et al., 2006)...
  43. Dietary Lipids and Silica-Accelerated Autoimmunity
    James J Pestka; Fiscal Year: 2013
    ..S. The prevalence of autoimmune diseases is markedly impacted by environmental factors (e.g...
  44. Regulation of Innate and Adaptive Immunity in Human COPD and Emphysema
    Farrah Kheradmand; Fiscal Year: 2012
    ..Despite an overall decline in the smoking prevalence in the United States, smoking incidence remains higher in veterans when compared to the same age group in the ..
  45. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..sensitivity is reliably increased, correlates with disease severity and outcomes, and contributes to the high prevalence of sleep-disordered breathing...
  46. Ghrelin: Behavioral, Anatomical, and Physiological Components of Obesity
    BRETT JOHN WARREN TEUBNER; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): The prevalence of obesity and its associated deleterious health consequences is growing in the United States making it a critical area of research...
  47. Understanding Pain of Gastrointestinal Origin in Women that Serve in OEF/OIF
    Beverley Greenwood-Van Meerveld; Fiscal Year: 2013
    ..Recent findings have shown that female veterans have a high prevalence of posttraumatic stress disorder (PTSD) and chronic gastrointestinal symptoms compared to their male ..
  48. Surgical amelioration of type 2 diabetes: Hormones, microbiota and mitochondria
    PETER J contact HAVEL; Fiscal Year: 2010
    ..With the increased prevalence to type-2 diabetes mellitus (T2DM), new strategies for diabetes prevention are needed...
  49. Exome re-sequencing candidate loci for familial essential tremor
    Barry E Kosofsky; Fiscal Year: 2012
    ..provided by applicant): Essential tremor (ET) is one of the most common neurological disorders in humans with a prevalence reaching almost four percent...
  50. The genetics and pathophysiology of impaired Wnt signaling in metabolic syndrome
    Arya Mani; Fiscal Year: 2012
    ..early CAD, metabolic syndrome and osteoporosis for mutations in LRP6, in order to identify the spectrum and prevalence of LRP6 mutation and establish genotype-phenotype correlations...
  51. Neural Functioning of Feeding Centers in Obese Youth
    ROBERT STANLEY SHERWIN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Adolescent obesity is fueling the increase in the prevalence of T2DM in youth...
  52. Conditional HSF1 Expression for Ischemic Cardioprotection
    Ivor J Benjamin; Fiscal Year: 2012
    ..Ischemic heart disease-the most common acquired heart disease in both men and women- has a higher prevalence in veterans of both sexes due to higher rates of obesity and cigarette use than the general population...
  53. Effects of Standardized Aerobic Exercise-Training on Neurocognitive and Neurodege
    Thomas O Obisesan; Fiscal Year: 2010
    ..Given that AAs: i) have higher incidence and prevalence of AD than Caucasians, ii) have paucity of cross-sectional, and lack prospective data on the beneficial effect ..
  54. Stem Cell Homing for Treatment of Female Pelvic Floor Disorders
    Margot S Damaser; Fiscal Year: 2013
    ..Since age, diabetes, and obesity are risk factors for FPFD, the aging US population and increasing prevalence of obesity and diabetes portend an FPFD epidemic in the U.S. in the coming decades...
  55. Targeting Cell Death to Prevent Ventricular Remodeling and Heart Failure
    Abhinav Diwan; Fiscal Year: 2011
    ..Project Narrative Heart failure is a very common disease of the aging population, with the highest incidence and prevalence in the age group above 65, which is also the largest Veteran population group (more than 40%)...
  56. 4th ASM Conference on Prokaryotic Cell Biology and Development
    Susan S Golden; Fiscal Year: 2012
    ..These insights into cell function are vitally important because of the increasing prevalence of antibiotic resistant pathogens...
  57. Predicting Bilirubin-induced Auditory Toxicity in Infants with Severe Jaundice
    Sanjiv B Amin; Fiscal Year: 2010
    ..Because the prevalence of severe jaundice is low in the USA, an international collaborative study is required, that includes infants ..
  58. Effect of diet & commensal bacteria on diabetes outcome in NOD mouse
    Li Wen; Fiscal Year: 2010
    ..To account for these changes in incidence and prevalence, the "Hygiene" or "Old Friends" hypothesis has been suggested...
  59. Non-invasive zoonotic pathogen exposure and outcome biomarkers with follow-up in
    Christopher D Heaney; Fiscal Year: 2013
    ..Devon Hall of the Rural Empowerment Association for Community Help (REACH) - from a CBPR cross-sectional MDRSA prevalence study among livestock workers and household members to a community-based participatory panel study among ..
  60. Identification of Compounds to treat Charcot-Marie-Tooth type 2E neuropathy
    RONALD K LIEM; Fiscal Year: 2010
    ..CMT is the most commonly inherited neurological disorder with a reported prevalence of 1 in 2,500 people worldwide. It is found in all races and ethnic groups...
  61. Role of GDNF in the regulation of hepatic steatosis
    SHANTHI K SRINIVASAN; Fiscal Year: 2013
    ..Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease in Veterans and its prevalence continues to increase, with the growing obesity epidemic...
  62. Respiratory and autonomic plasticity following intermittent hypoxia
    JASON HAROLD MATEIKA; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: Narrative The prevalence of obstructive sleep apnea is high in the Veteran population...
  63. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..Preliminary data demonstrated a high prevalence of risk factors: 62% of recruited participants are hypertensive, 59% of the women and 43% of men are obese (BMI &..
  64. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..Preliminary data demonstrated a high prevalence of risk factors: 62% of recruited participants are hypertensive, 59% of the women and 43% of men are obese (BMI &..
  65. JACKSON HEART STUDY
    Asoka Srinivasan; Fiscal Year: 2010
    ..Preliminary data demonstrated a high prevalence of risk factors: 62% of recruited participants are hypertensive, 59% of the women and 43% of men are obese (BMI &..
  66. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2013
    ..Preliminary data demonstrated a high prevalence of risk factors: 62% of recruited participants are hypertensive, 59% of the women and 43% of men are obese (BMI &..
  67. The Impact of Obstructive Sleep Apnea on Non-Alcoholic Fatty Liver Disease
    KATHLEEN ELIZABETH COREY; Fiscal Year: 2013
    ..Corey's proposal will focus on testing three hypotheses;1) OSA is associated with an increased prevalence of NAFLD, 2) The interaction between OSA and NAFLD is mediated by lipid peroxidation as measured by OxLDL and 3) ..
  68. Development and Validation of an Instrument to Assess Cognitive Function Regulati
    Xi Chen; Fiscal Year: 2013
    ..assessment focusing on oral hygiene status, denture hygiene (if applicable), gum inflammation and dental caries prevalence. The association between oral health measures and DRF in cognitively-impaired patients will be examined to ..
  69. Study of zidovudine addition in HIV-associated neurocognitive disorders
    Albert Anderson; Fiscal Year: 2013
    ..The CNS complications of HIV continue to be a major source of morbidity and mortality. The prevalence of HIV-associated neurocognitive disorder (HAND) is increasing...
  70. Mechanisms Regulating Reduced c-Kit-Dependent EAE Susceptibility in Male SJL Mice
    MELISSA ANN BROWN; Fiscal Year: 2013
    ..The prevalence of this disease is estimated to be at least three times greater in females than males and while genetic, ..
  71. New drug VS-110 for treating inflammatory bowel diseases
    Jinshyun Ruth Wu-Wong; Fiscal Year: 2013
    ..IBD primarily includes ulcerative colitis (UC) and Crohn's disease (CD). In the West, the prevalence has increased in the past 50 years to 120-200/100,000 persons for UC and 50-200/100,000 persons for CD...
  72. Mindfulness Based Stress Reduction as an Adjunctive Treatment for Psoriasis
    Jan A Moynihan; Fiscal Year: 2013
    ..Psoriasis is an inflammatory skin disease, and may also be a systemic condition associated with increased prevalence of metabolic syndrome;it affects millions of individuals in the US and is associated with significant heath care ..
  73. Characterization of an essential mitochondrial rRNA methyltransferase
    Kip E Guja; Fiscal Year: 2013
    ..diseases have a large impact in the population since, when considered as a class, they are estimated to have a prevalence of at least 1 in 5000...
  74. Real-Time Optical Diagnosis of Inflammatory Bowel Disease using SFDI
    Sylvain Gioux; Fiscal Year: 2013
    ..Given that IBD has a prevalence of over 1...
  75. Early social stress, novelty seeking, and impulsive behavior
    David M Lyons; Fiscal Year: 2013
    ..Novelty seeking can be costly, however, as it increases the prevalence of reckless driving, pathological gambling, unprotected sex, under-age drinking, and other forms of alcohol and ..
  76. Prevalence and Impact of Frailty among Dialysis Patients
    Kirsten L Johansen; Fiscal Year: 2013
    ..The specific research to be supported under this award is an exploration of the prevalence and significance of frailty among patients new to dialysis...
  77. Graves'Disease Therapy Risks to Mother and Fetus
    Scott A Rivkees; Fiscal Year: 2013
    ..Databases will be analyzed to assess the prevalence of GD in pregnancy, ATD treatment use in pregnant women with GD, co-morbid conditions (i.e...
  78. Misregulation of receptor tyrosine kinase signaling in PKD
    Jordan A Kreidberg; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Polycystic kidney disease (PKD) is a hereditary disease with a high prevalence and without a cure. PKD is characterized by numerous cysts within the kidneys of afflicted individuals...
  79. RYGB Improves Metabolism by Interrupting the Gastric Adipose Tissue Axis
    Naji N Abumrad; Fiscal Year: 2013
    ..More alarming is the increase in prevalence of "super-obesity" (Class III obese) reaching in some localities 7% of the population, as in Tennessee where the ..
  80. Air Toxics, Neighborhood Environment and Risk of Oral Clefts
    Philip J Lupo; Fiscal Year: 2013
    ..little is known about the etiology of CL[unreadable]P , and there are currently no strategies for reducing its prevalence. Because of this, the identification of risk factors for CL[unreadable]P is part of the National Institute of ..
  81. Body composition, bone structure, and joint damage in rheumatoid arthritis
    Joshua F Baker; Fiscal Year: 2013
    ..1 Recent studies suggest a greater prevalence and severity of arthritis in US veterans, compared with non-veterans...
  82. Role in Myopia Development of Retinal Pigment Epithelium - A New Therapeutic Targ
    Yan Zhang; Fiscal Year: 2013
    ..It is the product of eyes growing excessively long. The prevalence and the severity of myopia have risen worldwide during the past several decades, stimulating increased research ..
  83. Functional Studies of Variants of the Bipolar Risk Gene CACNA1C in Human Neurons
    JEN PAN; Fiscal Year: 2013
    ..Bipolar disorder is a chronic and severe mental illness with 1-2% lifetime prevalence in population of the United States...
  84. Mediators &prognostic value of muscle mass &function in chronic kidney disease
    Francis Perry Wilson; Fiscal Year: 2013
    ..Insufficiency Cohort (CRIC), we will leverage multiple measures of muscle mass and function to characterize the prevalence, predictors, and impact of muscle loss and muscle dysfunction in a broad and diverse CKD population...
  85. Endothelial Cell Dysregulation in Neovascular AMD
    Mark E Kleinman; Fiscal Year: 2013
    ..AMD is a devastating blinding disease that affects as many as 10 million Americans, a number that rivals the prevalence of all cancers combined and is unfortunately expected to double by 2020...
  86. Liver cancer risk and prevention among persons living with HIV/AIDS
    LESLEY SUEJEAN PARK; Fiscal Year: 2013
    ..The aging of this population, impaired immune function, and high prevalence of liver cancer risk factors hepatitis C virus, hepatitis B virus, an alcohol abuse and dependency contribute to ..
  87. Integrated PTSD and Smoking Treatment
    Mark B Powers; Fiscal Year: 2013
    ..PTSD is associated with increased smoking and failed cessation attempts.2-7 The prevalence of smoking in persons with PTSD is 44.6 %, compared to 22.5% in persons with no psychiatric disorder...
  88. The Role of Syntrophic Bacteria in Methanogenic Metabolism in the Human Gut
    Catherine Lozupone; Fiscal Year: 2013
    ..e. have a higher influence on community composition and function than their prevalence would suggest) and 3) they closely associate with specific syntrophic bacteria in other environments such as ..
  89. Antiviral prophylaxis to prevent perinatal transmission of HBV in Thailand
    GONZAGUE JOSEPH JOURDAIN; Fiscal Year: 2013
    ..About 7% of Thai adults are HBsAg carriers. Universal immunization programs have dramatically reduced the prevalence of infection wherever they have been implemented...
  90. Impact of Cardiovascular and Weight Loss diets on Uric Acid and Gout Risk
    Hyon K Choi; Fiscal Year: 2013
    ..With the continued "western" lifestyle in the US, the prevalence and incidence of gout have increased over the last few decades and it is estimated that 3.9% of US adults (8...
  91. Delivery of Polyphenols in Gum for Treatment of Gingivitis
    Craig S Miller; Fiscal Year: 2013
    ..S., with an even higher prevalence in the underserved and developing and undeveloped countries...
  92. Coronary Artery Risk Development in Young Adults (CARDIA) Study - CC
    James Shikany; Fiscal Year: 2012
    ..possible racial differences in CVD pathogenesis, we will compare the factors associated with CAC incidence and prevalence, and with IMT prevalence, across risk-gender groups...
  93. A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and Anxiety
    Michelle A Williams; Fiscal Year: 2013
    ..We will study the relation of maternal history of childhood sexual abuse, lifetime- and pregnancy-IPV with the prevalence of mood and anxiety disorders (e.g...
  94. Diet, Insulin, Dopamine, and Reward.
    Margaret E Rice; Fiscal Year: 2013
    ..The increasing prevalence of insulin resistance and obesity and the high comorbidity of disordered eating and substance abuse indicate ..
  95. Obesity, Biomechanics, and Inflammation in Osteoarthritis
    Farshid Guilak; Fiscal Year: 2013
    ..As the prevalence of obesity has risen dramatically in the past two decades, we now know that obesity is likely to be the primary ..
  96. Immune-based detection of rifampicin-resistance in HIV/TB
    Gregory P Bisson; Fiscal Year: 2013
    ..INH) and rifampicin, has become a public health emergency in some parts of sub-Saharan Africa, where the HIV prevalence and TB incidence rates are the highest in the world...
  97. Recombinant Polymers for Transarterial Chemoembolization of Liver Cancer
    AZADEH POURSAID; Fiscal Year: 2013
    ..carcinoma (HCC) of the liver is diagnosed in over 500,000 people annually and trends indicate increasing prevalence. Current improvements in diagnosis and treatment, however, have not produced an increase in survival rates...