internet

Summary

Summary: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

Top Publications

  1. pmc MUSCLE: multiple sequence alignment with high accuracy and high throughput
    Robert C Edgar
    Nucleic Acids Res 32:1792-7. 2004
  2. pmc Bioconductor: open software development for computational biology and bioinformatics
    Robert C Gentleman
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Genome Biol 5:R80. 2004
  3. pmc WebLogo: a sequence logo generator
    Gavin E Crooks
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Genome Res 14:1188-90. 2004
  4. pmc Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    Ron Edgar
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Lister Hill Center, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 30:207-10. 2002
  5. ncbi Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes
    A Krogh
    Center for Biological Sequence Analysis, Technical University of Denmark, Building 208, 2800 Lyngby, Denmark
    J Mol Biol 305:567-80. 2001
  6. pmc The Protein Data Bank
    H M Berman
    Research Collaboratory for Structural Bioinformatics RCSB, Rutgers University, Piscataway, NJ 08854 8087, USA
    Nucleic Acids Res 28:235-42. 2000
  7. pmc Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    Jeremy Goecks
    Department of Biology and Department of Mathematics and Computer Science, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA
    Genome Biol 11:R86. 2010
  8. pmc OrthoMCL: identification of ortholog groups for eukaryotic genomes
    Li Li
    Department of Biology and Genetics, Center for Bioinformatics, and Genomics Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Genome Res 13:2178-89. 2003
  9. pmc Cytoscape: a software environment for integrated models of biomolecular interaction networks
    Paul Shannon
    Institute for Systems Biology, Seattle, Washington 98103, USA
    Genome Res 13:2498-504. 2003
  10. pmc dbSNP: the NCBI database of genetic variation
    S T Sherry
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA
    Nucleic Acids Res 29:308-11. 2001

Detail Information

Publications280 found, 100 shown here

  1. pmc MUSCLE: multiple sequence alignment with high accuracy and high throughput
    Robert C Edgar
    Nucleic Acids Res 32:1792-7. 2004
    ..The MUSCLE program, source code and PREFAB test data are freely available at http://www.drive5. com/muscle...
  2. pmc Bioconductor: open software development for computational biology and bioinformatics
    Robert C Gentleman
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Genome Biol 5:R80. 2004
    ..We describe details of our aims and methods, identify current challenges, compare Bioconductor to other open bioinformatics projects, and provide working examples...
  3. pmc WebLogo: a sequence logo generator
    Gavin E Crooks
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Genome Res 14:1188-90. 2004
    ..A command line interface and the complete, open WebLogo source code are available for local installation and customization...
  4. pmc Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    Ron Edgar
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Lister Hill Center, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 30:207-10. 2002
    ..A series organizes samples into the meaningful data sets which make up an experiment. The GEO repository is publicly accessible through the World Wide Web at http://www.ncbi.nlm.nih.gov/geo...
  5. ncbi Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes
    A Krogh
    Center for Biological Sequence Analysis, Technical University of Denmark, Building 208, 2800 Lyngby, Denmark
    J Mol Biol 305:567-80. 2001
    ..We discuss the possible relevance of this finding for our understanding of membrane protein assembly mechanisms. A TMHMM prediction service is available at http://www.cbs.dtu.dk/services/TMHMM/...
  6. pmc The Protein Data Bank
    H M Berman
    Research Collaboratory for Structural Bioinformatics RCSB, Rutgers University, Piscataway, NJ 08854 8087, USA
    Nucleic Acids Res 28:235-42. 2000
    ..This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans for the future development of the resource...
  7. pmc Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    Jeremy Goecks
    Department of Biology and Department of Mathematics and Computer Science, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA
    Genome Biol 11:R86. 2010
    ..Galaxy Pages are interactive, web-based documents that provide users with a medium to communicate a complete computational analysis...
  8. pmc OrthoMCL: identification of ortholog groups for eukaryotic genomes
    Li Li
    Department of Biology and Genetics, Center for Bioinformatics, and Genomics Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Genome Res 13:2178-89. 2003
    ..cbil.upenn.edu/gene-family). Analysis of clusters incorporating P. falciparum genes identifies numerous enzymes that were incompletely annotated in first-pass annotation of the parasite genome...
  9. pmc Cytoscape: a software environment for integrated models of biomolecular interaction networks
    Paul Shannon
    Institute for Systems Biology, Seattle, Washington 98103, USA
    Genome Res 13:2498-504. 2003
    ....
  10. pmc dbSNP: the NCBI database of genetic variation
    S T Sherry
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA
    Nucleic Acids Res 29:308-11. 2001
    ..The complete contents of dbSNP are available to the public at website: http://www.ncbi.nlm.nih.gov/SNP. The complete contents of dbSNP can also be downloaded in multiple formats via anonymous FTP at ftp://ncbi.nlm.nih.gov/snp/...
  11. pmc Mfold web server for nucleic acid folding and hybridization prediction
    Michael Zuker
    Department of Mathematical Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Nucleic Acids Res 31:3406-15. 2003
    ..The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'...
  12. pmc CONSORT-EHEALTH: improving and standardizing evaluation reports of Web-based and mobile health interventions
    Gunther Eysenbach
    University Health Network, Centre for Global eHealth Innovation and Techna Institute, Toronto, Ontario, Canada
    J Med Internet Res 13:e126. 2011
    Web-based and mobile health interventions (also called "Internet interventions" or "ehealth/mhealth interventions") are tools or treatments, typically behaviorally based, that are operationalized and transformed for delivery via the ..
  13. pmc Database resources of the National Center for Biotechnology Information
    Eric W Sayers
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D13-25. 2012
    ..Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov...
  14. pmc SIFT: Predicting amino acid changes that affect protein function
    Pauline C Ng
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N A1 162, Seattle, WA 98109, USA
    Nucleic Acids Res 31:3812-4. 2003
    ..We have shown that SIFT can distinguish between functionally neutral and deleterious amino acid changes in mutagenesis studies and on human polymorphisms. SIFT is available at http://blocks.fhcrc.org/sift/SIFT.html...
  15. pmc Galaxy: a platform for interactive large-scale genome analysis
    Belinda Giardine
    Center for Comparative Genomics and Bioinformatics, Huck Institutes for Life Sciences, Penn State University, University Park, Pennsylvania 16802, USA
    Genome Res 15:1451-5. 2005
    ..Galaxy can be accessed at http://g2.bx.psu.edu...
  16. pmc Reactome: a database of reactions, pathways and biological processes
    David Croft
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 39:D691-7. 2011
    ..The resulting inferred pathway sets can be browsed and analyzed with our Species Comparison tool. Collaborations are also underway to create manually curated data sets on the Reactome framework for chicken, Drosophila and rice...
  17. ncbi Primer3 on the WWW for general users and for biologist programmers
    S Rozen
    Whitehead Institute for Biomedical Research, Cambridge, MA, USA
    Methods Mol Biol 132:365-86. 2000
  18. pmc InterProScan: protein domains identifier
    E Quevillon
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 33:W116-20. 2005
    ..O'Reilly Publishers, Sebastopol, CA, http://www.w3.org/TR/soap/] are also available to the users. Various output formats are supported and include text tables, XML documents, as well as various graphs to help interpret the results...
  19. pmc The HHpred interactive server for protein homology detection and structure prediction
    Johannes Söding
    Department of Protein Evolution, Max Planck Institute for Developmental Biology Spemannstrasse 35, 72076 Tubingen, Germany
    Nucleic Acids Res 33:W244-8. 2005
    ..A detailed help facility is available. As a demonstration, we analyze the sequence of SpoVT, a transcriptional regulator from Bacillus subtilis. HHpred can be accessed at http://protevo.eb.tuebingen.mpg.de/hhpred...
  20. pmc The IntAct molecular interaction database in 2012
    Samuel Kerrien
    EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 40:D841-6. 2012
    ..IntAct is an active contributor to the IMEx consortium (http://www.imexconsortium.org). IntAct source code and data are freely available at http://www.ebi.ac.uk/intact...
  21. pmc The UCSC Genome Browser database: extensions and updates 2011
    Timothy R Dreszer
    Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA
    Nucleic Acids Res 40:D918-23. 2012
    ..We have also introduced several usability features including track search and a context-sensitive menu of options available with a right-click anywhere on the Browser's image...
  22. pmc An efficient algorithm for large-scale detection of protein families
    A J Enright
    Computational Genomics Group, The European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge CB10 1SD, UK
    Nucleic Acids Res 30:1575-84. 2002
    ..The method has been used to detect and categorise protein families within the draft human genome and the resulting families have been used to annotate a large proportion of human proteins...
  23. pmc Human non-synonymous SNPs: server and survey
    Vasily Ramensky
    European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 30:3894-900. 2002
    ..The strongest selective pressure was detected for proteins involved in transcription regulation...
  24. pmc The IntAct molecular interaction database in 2010
    B Aranda
    EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 38:D525-31. 2010
    ..Specialized views then allows 'zooming in' on the full annotation of interactions, interactors and their properties. IntAct source code and data are freely available at http://www.ebi.ac.uk/intact...
  25. pmc TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes
    V Matys
    BIOBASE GmbH, Halchtersche Strasse 33, D 38304 Wolfenbuttel, Germany
    Nucleic Acids Res 34:D108-10. 2006
    ..The here described public releases, TRANSFAC 7.0 and TRANSCompel 7.0, are accessible under http://www.gene-regulation.com/pub/databases.html...
  26. pmc Database resources of the National Center for Biotechnology Information
    Eric W Sayers
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 38:D5-16. 2010
    ..Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. All these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov...
  27. pmc The metagenomics RAST server - a public resource for the automatic phylogenetic and functional analysis of metagenomes
    F Meyer
    Mathematics and Computer Science Division, Argonne National Laboratory, 9700 S Cass Avenue, Argonne, IL 60439, USA
    BMC Bioinformatics 9:386. 2008
    ..High-throughput, low-cost next-generation sequencing has provided access to metagenomics to a wide range of researchers...
  28. pmc The RCSB Protein Data Bank: redesigned web site and web services
    Peter W Rose
    San Diego Supercomputer Center, University of California San Diego, 9500 Gilman Drive, Mailcode 0743, La Jolla, CA 92093 0743, USA
    Nucleic Acids Res 39:D392-401. 2011
    ..These improvements enable a range of new possibilities to analyze and understand structure data. The next generation of the RCSB PDB web site, as described here, provides a rich resource for research and education...
  29. pmc Plant cis-acting regulatory DNA elements (PLACE) database: 1999
    K Higo
    Department of Genetic Resources, National Institute of Agrobiological Resources, 2 1 2 Kannondai, Tsukuba, Ibaraki 305, Japan
    Nucleic Acids Res 27:297-300. 1999
    ..This report summarizes the present status of this database and available tools...
  30. pmc miRBase: tools for microRNA genomics
    Sam Griffiths-Jones
    Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester, UK
    Nucleic Acids Res 36:D154-8. 2008
    ..miRBase is available at http://microrna.sanger.ac.uk/...
  31. pmc The law of attrition
    Gunther Eysenbach
    Centre for Global eHealth Innovation, University Health Network, 190 Elizabeth Street, Toronto ON, M5G 2C4, Canada
    J Med Internet Res 7:e11. 2005
    ..However, for many eHealth trials, in particular those conducted on the Internet and in particular with self-help applications, high dropout rates may be a natural and typical feature...
  32. pmc The microRNA.org resource: targets and expression
    Doron Betel
    Computational and Systems Biology Center, Memorial Sloan Kettering Cancer Center, NY, USA
    Nucleic Acids Res 36:D149-53. 2008
    ..The web resource provides users with functional information about the growing number of microRNAs and their interaction with target genes in many species and facilitates novel discoveries in microRNA gene regulation...
  33. pmc The Pfam protein families database
    Robert D Finn
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Nucleic Acids Res 38:D211-22. 2010
    ..Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/)...
  34. ncbi Haploview: analysis and visualization of LD and haplotype maps
    J C Barrett
    Whitehead Institute for Biomedical Research Cambridge, MA 02142, USA
    Bioinformatics 21:263-5. 2005
    ..Haploview is a software package that provides computation of linkage disequilibrium statistics and population haplotype patterns from primary genotype data in a visually appealing and interactive interface...
  35. pmc The RCSB Protein Data Bank: new resources for research and education
    Peter W Rose
    San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093 0743, USA
    Nucleic Acids Res 41:D475-82. 2013
    ..These improvements enable new opportunities for analyzing and understanding structure data...
  36. pmc The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
    Ron Caspi
    SRI International, 333 Ravenswood, Menlo Park, CA 94025, USA, USA
    Nucleic Acids Res 40:D742-53. 2012
    ..New developments include a zoomable web interface for diagrams; flux-balance analysis model generation from PGDBs; web services; and a new tool called Web Groups...
  37. pmc BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
    Chunlei Wu
    Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Dr, San Diego, CA 92121, USA
    Genome Biol 10:R130. 2009
    ..gnf.org, a centralized gene portal for aggregating distributed gene annotation resources. Moreover, BioGPS embraces the principle of community intelligence, enabling any user to easily and directly contribute to the BioGPS platform...
  38. pmc The UCSC Genome Browser database: update 2011
    Pauline A Fujita
    Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA
    Nucleic Acids Res 39:D876-82. 2011
    ..New data highlights include seven new genome assemblies, a Neandertal genome data portal, phenotype and disease association data, a human RNA editing track, and a zebrafish Conservation track. We also describe updates to existing tracks...
  39. pmc Persuasive system design does matter: a systematic review of adherence to web-based interventions
    Saskia M Kelders
    Center for eHealth Research and Disease Management, Department of Psychology, Health and Technology, University of Twente, Enschede, Netherlands
    J Med Internet Res 14:e152. 2012
    ..In this paper we examine technology from a holistic perspective. We see it as a vital and inseparable aspect of web-based interventions to help explain and understand adherence...
  40. ncbi Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research
    Ana Conesa
    Centro de Genomica, Instituto Valenciano de Investigaciones Agrarias, Moncada, Valencia, Spain
    Bioinformatics 21:3674-6. 2005
    ..This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application that allows monitoring and comprehension of the whole annotation and analysis process...
  41. ncbi Detecting influenza epidemics using search engine query data
    Jeremy Ginsberg
    Google Inc, 1600 Amphitheatre Parkway, Mountain View, California 94043, USA
    Nature 457:1012-4. 2009
    ..This approach may make it possible to use search queries to detect influenza epidemics in areas with a large population of web search users...
  42. pmc ArrayExpress update--trends in database growth and links to data analysis tools
    Gabriella Rustici
    Functional Genomics Team, EMBL EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
    Nucleic Acids Res 41:D987-90. 2013
    ..Additionally, R objects, for microarray data, and binary alignment format files, for sequencing data, have been generated for a significant proportion of ArrayExpress data...
  43. pmc WoLF PSORT: protein localization predictor
    Paul Horton
    Computational Biology Research Center, AIST, Tokyo, Japan
    Nucleic Acids Res 35:W585-7. 2007
    ..Taken together, this information allows a user to understand the evidence (or lack thereof) behind the predictions made for particular proteins. WoLF PSORT is available at wolfpsort.org...
  44. ncbi GenePattern 2.0
    Michael Reich
    Nat Genet 38:500-1. 2006
  45. pmc miRBase: microRNA sequences, targets and gene nomenclature
    Sam Griffiths-Jones
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nucleic Acids Res 34:D140-4. 2006
    ..miRBase Sequences is the primary online repository for miRNA sequence data and annotation. miRBase Targets is a comprehensive new database of predicted miRNA target genes. miRBase is available at http://microrna.sanger.ac.uk/...
  46. pmc The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes
    Ross Overbeek
    Fellowship for Interpretation of Genomes, 15W155 81st Street, Burr Ridge, IL 60527, USA
    Nucleic Acids Res 33:5691-702. 2005
    ..The initial release of data includes 180 177 distinct proteins with 2133 distinct functional roles. This data comes from 173 subsystems and 383 different organisms...
  47. pmc Ensembl's 10th year
    Paul Flicek
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 38:D557-62. 2010
    ....
  48. pmc InParanoid 7: new algorithms and tools for eukaryotic orthology analysis
    Gabriel Ostlund
    Department of Biochemistry and Biophysics, Stockholm Bioinformatics Centre, AlbaNova University Centre, Stockholm University, SE 10691 Stockholm, Sweden
    Nucleic Acids Res 38:D196-203. 2010
    ..To facilitate data exchange and comparisons among ortholog databases, we have developed and are making available two XML schemas: SeqXML for the input sequences and OrthoXML for the output ortholog clusters...
  49. pmc Cytoscape Web: an interactive web-based network browser
    Christian T Lopes
    Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
    Bioinformatics 26:2347-8. 2010
    ..Multiple file exchange formats can be used to load data into Cytoscape Web, including GraphML, XGMML and SIF...
  50. pmc Entrez Gene: gene-centered information at NCBI
    Donna Maglott
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20852, USA
    Nucleic Acids Res 39:D52-7. 2011
    ....
  51. pdf DAVID: Database for Annotation, Visualization, and Integrated Discovery
    Glynn Dennis
    Science Applications International Corporation Frederick, Clinical Services Program, Laboratory of Immunopathogenesis and Bioinformatics, National Cancer Institute at Frederick, MD 21702, USA
    Genome Biol 4:P3. 2003
    ..A more judicious approach is to provide query-based access to an integrated database that disseminates biologically rich information across large datasets and displays graphic summaries of functional information...
  52. pmc GenBank
    Dennis A Benson
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D48-53. 2012
    ..Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI home page: www.ncbi.nlm.nih.gov...
  53. pmc WebGestalt: an integrated system for exploring gene sets in various biological contexts
    Bing Zhang
    Graduate School in Genome Science and Technology, University of Tennessee Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Nucleic Acids Res 33:W741-8. 2005
    ..Exploration of all the 48 gene sets using WebGestalt is available for the public at http://genereg.ornl.gov/webgestalt/wg_enrich.php...
  54. pmc The COG database: a tool for genome-scale analysis of protein functions and evolution
    R L Tatusov
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 28:33-6. 2000
    ..The COG database is accompanied by the COGNITOR program that is used to fit new proteins into the COGs and can be applied to functional and phylogenetic annotation of newly sequenced genomes...
  55. pmc Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
    William McLaren
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Bioinformatics 26:2069-70. 2010
    ..In Ensembl, a web-based tool (the SNP Effect Predictor) and API interface can now functionally annotate variants in all Ensembl and Ensembl Genomes supported species...
  56. pmc Biopython: freely available Python tools for computational molecular biology and bioinformatics
    Peter J A Cock
    Plant Pathology, SCRI, Invergowrie, Dundee, UK
    Bioinformatics 25:1422-3. 2009
    ....
  57. pmc PROSITE, a protein domain database for functional characterization and annotation
    Christian J A Sigrist
    Structural Biology and Bioinformatics Department, University of Geneva, Swiss Institute of Bioinformatics, Centre Medical Universitaire, CH 1211 Geneva 4, Switzerland
    Nucleic Acids Res 38:D161-6. 2010
    ..The latest version of PROSITE (release 20.54, of 22 September 2009) contains 1308 patterns, 863 profiles and 869 ProRules. PROSITE is accessible at: http://www.expasy.org/prosite/...
  58. pmc Genenames.org: the HGNC resources in 2013
    Kristian A Gray
    HUGO Gene Nomenclature Committee, European Bioinformatics Institute EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 41:D545-52. 2013
    ..The site provides a public access portal to our database with no restrictions imposed on access or the use of the data. Within this article, we review our online resources and data with particular emphasis on the updates to our website...
  59. pmc SMART 6: recent updates and new developments
    Ivica Letunic
    EMBL, Meyerhofstrasse 1, 69012 Heidelberg, Germany
    Nucleic Acids Res 37:D229-32. 2009
    ..In addition to the standard web access to the database, users can now query SMART using distributed annotation system (DAS) or through a simple object access protocol (SOAP) based web service...
  60. ncbi Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation
    Ivica Letunic
    EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Bioinformatics 23:127-8. 2007
    ..Various types of data such as genome sizes or protein domain repertoires can be mapped onto the tree. Export to several bitmap and vector graphics formats is supported. AVAILABILITY: iTOL is available at http://itol.embl.de..
  61. pmc MINT, the molecular interaction database: 2009 update
    Arnaud Ceol
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome
    Nucleic Acids Res 38:D532-9. 2010
    ..MINT has adopted the PSI-MI standards for the annotation and for the representation of molecular interactions and is a member of the IMEx consortium...
  62. pmc PID: the Pathway Interaction Database
    Carl F Schaefer
    National Cancer Institute, Center for Biomedical Informatics and Information Technology, Rockville MD, USA
    Nucleic Acids Res 37:D674-9. 2009
    ..The database is updated with new pathway content every month and supplemented by specially commissioned articles on the practical uses of other relevant online tools...
  63. pmc AmiGO: online access to ontology and annotation data
    Seth Carbon
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 25:288-9. 2009
    ..AmiGO is free open source software developed and maintained by the GO Consortium...
  64. pmc Using the internet to promote health behavior change: a systematic review and meta-analysis of the impact of theoretical basis, use of behavior change techniques, and mode of delivery on efficacy
    Thomas L Webb
    Department of Psychology, University of Sheffield, Western Bank, Sheffield, UK
    J Med Internet Res 12:e4. 2010
    The Internet is increasingly used as a medium for the delivery of interventions designed to promote health behavior change...
  65. pmc New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
    Ian Sillitoe
    Institute of Structural and Molecular Biology, Division of Biosciences, University College London, Gower Street, London WC1E 6BT, UK
    Nucleic Acids Res 41:D490-8. 2013
    ..The CATH website has been redesigned. We have improved the display of functional data and of conserved sequence features associated with FunFams within each CATH superfamily...
  66. ncbi Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: a meta-analysis
    Viola Spek
    Department of Psychology and Health, Tilburg University, The Netherlands
    Psychol Med 37:319-28. 2007
    We studied to what extent internet-based cognitive behaviour therapy (CBT) programs for symptoms of depression and anxiety are effective.
  67. ncbi Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
    E Krissinel
    European Bioinformatics Institute, Genome Campus, Hinxton, Cambridge CB10 1SD, England
    Acta Crystallogr D Biol Crystallogr 60:2256-68. 2004
    ..A new score, balancing the r.m.s.d. and alignment length Nalign, is proposed. It is found that different servers agree reasonably well on the new score, while showing considerable differences in r.m.s.d. and Nalign...
  68. ncbi Some remarks on protein attribute prediction and pseudo amino acid composition
    Kuo Chen Chou
    Gordon Life Science Institute, 13784 Torrey Del Mar Drive, San Diego, CA 92130, USA
    J Theor Biol 273:236-47. 2011
    ....
  69. ncbi IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
    Zsuzsanna Dosztanyi
    Institute of Enzymology, BRC, Hungarian Academy of Sciences, PO Box 7, H 1518 Budapest, Hungary
    Bioinformatics 21:3433-4. 2005
    ..Optional to the prediction are built-in parameter sets optimized for predicting short or long disordered regions and structured domains...
  70. ncbi Internet-based and other computerized psychological treatments for adult depression: a meta-analysis
    Gerhard Andersson
    Department of Behavioural Sciences and Learning, Swedish Institute for Disability Research, Linkoping University, Linkoping, Sweden
    Cogn Behav Ther 38:196-205. 2009
    Computerized and, more recently, Internet-based treatments for depression have been developed and tested in controlled trials...
  71. pmc CD-HIT Suite: a web server for clustering and comparing biological sequences
    Ying Huang
    California Institute for Telecommunications and Information Technology, University of California San Diego, La Jolla, CA, USA
    Bioinformatics 26:680-2. 2010
    ..Users can now interactively explore the clusters within web browsers. We also provide downloadable clusters for several public databases (NCBI NR, Swissprot and PDB) at different identity levels...
  72. pmc KEGG for representation and analysis of molecular networks involving diseases and drugs
    Minoru Kanehisa
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Nucleic Acids Res 38:D355-60. 2010
    ..The new disease/drug information resource named KEGG MEDICUS can be used as a reference knowledge base for computational analysis of molecular networks, especially, by integrating large-scale experimental datasets...
  73. pmc JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update
    Jan Christian Bryne
    Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate 55, N 5008 Bergen, Norway
    Nucleic Acids Res 36:D102-6. 2008
    ..JASPAR is available at http://jaspar.genereg.net...
  74. pmc The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
    David Warde-Farley
    Department of Computer Science, University of Toronto, Toronto, Ontario, Canada
    Nucleic Acids Res 38:W214-20. 2010
    ..The high accuracy of the GeneMANIA prediction algorithm, an intuitive user interface and large database make GeneMANIA a useful tool for any biologist...
  75. pmc The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
    Ron Caspi
    SRI International, 333 Ravenswood, Menlo Park, CA 94025, USA
    Nucleic Acids Res 38:D473-9. 2010
    ..The BioCyc PGDBs generated by SRI are offered for adoption by any party interested in curation of metabolic, regulatory, and genome-related information about an organism...
  76. pmc WormBase 2012: more genomes, more data, new website
    Karen Yook
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Nucleic Acids Res 40:D735-41. 2012
    ..We report on the growth of our database and on our work in keeping pace with the growing demand for data, efforts to anticipate the requirements of users and new collaborations with the larger science community...
  77. ncbi Improved prediction of signal peptides: SignalP 3.0
    Jannick Dyrløv Bendtsen
    Center for Biological Sequence Analysis, BioCentrum DTU, Building 208, Technical University of Denmark, DK 2800 Lyngby, Denmark
    J Mol Biol 340:783-95. 2004
    ..The new method has been benchmarked against other available methods. Predictions can be made at the publicly available web server..
  78. pmc The TIGR Rice Genome Annotation Resource: improvements and new features
    Shu Ouyang
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 35:D883-7. 2007
    ..Enhanced data access is available through web interfaces, FTP downloads and a Data Extractor tool developed in order to support discrete dataset downloads...
  79. pmc Pathway Commons, a web resource for biological pathway data
    Ethan G Cerami
    Computational Biology Center, Memorial Sloan Kettering Cancer Center 1275 York Avenue, Box 460, New York, NY 10065, USA
    Nucleic Acids Res 39:D685-90. 2011
    ..Pathway Commons currently contains data from nine databases with over 1400 pathways and 687,000 interactions and will be continually expanded and updated...
  80. pmc Primer3Plus, an enhanced web interface to Primer3
    Andreas Untergasser
    Laboratory of Molecular Biology, Department of Plant Science, Wageningen University, Dreijenlaan 3, 6703HA, Wageningen, The Netherlands
    Nucleic Acids Res 35:W71-4. 2007
    ..The Primer3Plus Perl source code is available under GPL license from SourceForge. Primer3Plus is available at http://www.bioinformatics.nl/primer3plus...
  81. pmc Rfam: updates to the RNA families database
    Paul P Gardner
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK
    Nucleic Acids Res 37:D136-40. 2009
    ..Recent improvements to the website, methodologies and data used by Rfam are discussed. Rfam is freely available on the Web at http://rfam.sanger.ac.uk/and http://rfam.janelia.org/...
  82. pmc PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium
    Huaiyu Mi
    Evolutionary Systems Biology Group, SRI International, Lawrence Berkeley National Laboratory, USA
    Nucleic Acids Res 38:D204-10. 2010
    ..In addition, PANTHER trees are being annotated with gene function as part of the Gene Ontology Reference Genome project, resulting in an increasing number of curated functional annotations...
  83. pmc PubChem: a public information system for analyzing bioactivities of small molecules
    Yanli Wang
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 37:W623-33. 2009
    ..Most of the tools described in this work can be directly accessed at http://pubchem.ncbi.nlm.nih.gov/assay/. URLs for accessing other tools described in this work are specified individually...
  84. pmc The Vienna RNA websuite
    Andreas R Gruber
    Institute for Theoretical Chemistry, University of Vienna, Wahringerstrasse 17, 1090 Wien, Austria
    Nucleic Acids Res 36:W70-4. 2008
    ..The web server together with software packages for download is freely accessible at http://rna.tbi.univie.ac.at/...
  85. ncbi Network motifs: simple building blocks of complex networks
    R Milo
    Departments of Physics of Complex Systems and Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel 76100
    Science 298:824-7. 2002
    ..Motifs may thus define universal classes of networks. This approach may uncover the basic building blocks of most networks...
  86. pmc DrugBank: a knowledgebase for drugs, drug actions and drug targets
    David S Wishart
    Department of Computing Science, University of Alberta, Edmonton, AB, Canada T6G 2E8
    Nucleic Acids Res 36:D901-6. 2008
    ..DrugBank has also significantly improved the power and simplicity of its structure query and text query searches. DrugBank is available at http://www.drugbank.ca...
  87. pmc GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis
    Qi Zheng
    State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences and Graduate University of the Chinese Academy of Sciences, Beijing 100101, China
    Nucleic Acids Res 36:W358-63. 2008
    ..GOEAST also provides rigorous statistical tests to enhance the reliability of analysis results. GOEAST is freely accessible at http://omicslab.genetics.ac.cn/GOEAST/..
  88. pmc Which intervention characteristics are related to more exposure to internet-delivered healthy lifestyle promotion interventions? A systematic review
    Wendy Brouwer
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands
    J Med Internet Res 13:e2. 2011
    The Internet has become a popular medium for the delivery of tailored healthy lifestyle promoting interventions...
  89. pmc Chemical Entities of Biological Interest: an update
    Paula de Matos
    Chemoinformatics and Metabolism Team, European Bioinformatics Institute, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 38:D249-54. 2010
    ....
  90. pmc GenBank
    Dennis A Benson
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 38:D46-51. 2010
    ..Complete bi-monthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI homepage: www.ncbi.nlm.nih.gov...
  91. pmc BioMart Central Portal--unified access to biological data
    Syed Haider
    EMBL European Bioinformatics Institute, Hinxton, Cambridge CB10 1SD, Computer Laboratory, University of Cambridge, 15 JJ Thomson Avenue, Cambridge CB3 0FD, UK
    Nucleic Acids Res 37:W23-7. 2009
    ..The website is free and open to all users and there is no login requirement...
  92. pmc EcoCyc: a comprehensive view of Escherichia coli biology
    Ingrid M Keseler
    SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA
    Nucleic Acids Res 37:D464-70. 2009
    ..A new advanced query page guides users in interactively constructing complex database queries against EcoCyc. A Macintosh version of EcoCyc is now available. A series of Webinars is available to instruct users in the use of EcoCyc...
  93. pmc ELM: the status of the 2010 eukaryotic linear motif resource
    Cathryn M Gould
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 38:D167-80. 2010
    ..Using the links, researchers can explore the motifs, proteins, complex structures and associated literature to evaluate whether candidate motifs might be worth experimental investigation...
  94. pmc The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata
    Konstantinos Liolios
    Genome Biology Program, DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA, USA
    Nucleic Acids Res 38:D346-54. 2010
    ..GOLD is available at: http://www.genomesonline.org and has a mirror site at the Institute of Molecular Biology and Biotechnology, Crete, Greece, at: http://gold.imbb.forth.gr/..
  95. pmc The BioGRID Interaction Database: 2008 update
    Bobby Joe Breitkreutz
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Nucleic Acids Res 36:D637-40. 2008
    ..Source code for the BioGRID and the linked Osprey network visualization system is now freely available without restriction...
  96. pmc ENCODE whole-genome data in the UCSC Genome Browser
    Kate R Rosenbloom
    Center for Biomolecular Science and Engineering, School of Engineering, University of California, Santa Cruz, CA 95064, USA
    Nucleic Acids Res 38:D620-5. 2010
    ..The UCSC Genome Browser Database: update 2010, in this issue). The ENCODE web portal at UCSC (http://encodeproject.org or http://genome.ucsc.edu/ENCODE) provides information about the ENCODE data and convenient links for access...
  97. pmc Ensembl Genomes: extending Ensembl across the taxonomic space
    P J Kersey
    EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK
    Nucleic Acids Res 38:D563-9. 2010
    ..Additionally, extensive comparative analysis has been performed, both within defined clades and across the wider taxonomy, and sequence alignments and gene trees resulting from this can be accessed through the site...
  98. pmc The Arabidopsis Information Resource (TAIR): gene structure and function annotation
    David Swarbreck
    Carnegie Institution, Department of Plant Biology, 260 Panama St, Stanford, CA 94305, USA
    Nucleic Acids Res 36:D1009-14. 2008
    ..A total of 681 new genes and 1002 new splice variants were added. Overall, 10,098 loci (one-third of all loci from the previous TAIR6 release) were updated for the TAIR7 release...
  99. pmc Infrastructure for the life sciences: design and implementation of the UniProt website
    Eric Jain
    Swiss Prot group, Swiss Institute of Bioinformatics, CMU, 1 Michel Servet, 1211 Geneva 4, Switzerland
    BMC Bioinformatics 10:136. 2009
    ..Following several years of intense development and a year of public beta testing, the http://www.uniprot.org domain was switched to the newly developed site described in this paper in July 2008...
  100. ncbi Bio2RDF: towards a mashup to build bioinformatics knowledge systems
    François Belleau
    Centre de Recherche du CHUL, Universite Laval, 2705 Boulevard Laurier, Que, Canada G1V4G2
    J Biomed Inform 41:706-16. 2008
    ..The Bio2RDF repository can be queried at http://bio2rdf.org...

Research Grants105 found, 100 shown here

  1. Interactive Mature-Driver Safety and Decision Course
    BRIAN DANAHER; Fiscal Year: 2004
    ..The underlying theories for supporting behavior change are the Theory of Reasoned Action and Social Cognitive Theory. Phase I will target female mature-drivers and will be evaluated in a randomized trial. ..
  2. Pregnancy Prevention Program for the Learning Disabled
    BRIAN DANAHER; Fiscal Year: 2002
    ..This product will be attractive to people with learning disabilities and anyone serving this population (e.g., parents, schools, training centers, vocational and residential services, public health clinics, and group homes). ..
  3. A Multimedia Program to Promote Exercise by Older Adults
    A Irvine; Fiscal Year: 2005
    ..Delivered via Internet/Intranet or CD/DVD-ROM, the system may be used from homes or in conjunction with classes in senior centers...
  4. Multimedia Support for Caregivers of the Seriously Ill
    A Irvine; Fiscal Year: 2007
    ..The fully developed Phase II program will be produced in both Internet and CD-ROM versions and will be evaluated in a large randomized trial...
  5. INTERACTIVE TRAINING FOR PARENTS OF AT-RISK ADOLESCENTS
    A Irvine; Fiscal Year: 2003
    ..Benefits of the IMM format include: proven effectiveness, low-cost; individualized, self-paced mastery learning, easy scheduling for busy parents, and objective tracking of parents' progress. ..
  6. MULTIMEDIA ELDERCARE SUPPORT FOR FAMILY CAREGIVERS
    A Irvine; Fiscal Year: 2004
    ..The award-winning Phase I prototype will be marketed as a CD-ROM and in Internet/Intranet format. The Phase II program also will be produced in these formats.
  7. Training Parents to Advocate for Students with TBI
    A Irvine; Fiscal Year: 2006
    ..g., elementary or secondary), and (d) the information modules. In addition, a web-based bulletin board will provide social support to parents applying the advocacy skills in their own schools. ..
  8. CARE OF THE AGED: A MULTIMEDIA STAFF DEVELOPMENT PROGRAM
    A Irvine; Fiscal Year: 2002
    ..In Phase II, the program's content will be expanded, and it will be evaluated with a randomized trial at multiple residential worksites. PROPOSED COMMERCIAL APPLICATION: Not available ..
  9. Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
    Lawrence Chu; Fiscal Year: 2008
    ..abstract_text> ..
  10. Validation of Web-based Multimedia Dietary Assessment Tools
    Lenore Arab; Fiscal Year: 2010
    ..Theepidemiology. The study will als contribute to our confidence in these dietary and activity assessment instruments in multiracial populations. ..
  11. Cancer Pain Management-Decision Support Computer Program
    Eun Ok Im; Fiscal Year: 2007
    ..Using theoretical triangulation, a feminist approach and fuzzy logic will guide the research process. Innovative internet data collection methods will be used including a quantitative Internet survey among 400 cancer patients recruited ..
  12. A Multiethnic Internet Study on Menopausal Symptoms
    Eun Ok Im; Fiscal Year: 2008
    ..S., and few studies have been national in scope. With advances in computer technologies, the Internet now provides an excellent medium of national and international communication and allows people in different ..
  13. Bisphosphonate therapy for HIV-Associated osteopenia
    Jeannie Huang; Fiscal Year: 2005
    ..Finally, data generated by this pilot study will lay the foundation for future studies of bisphosphonate therapy in HIV-infected persons with bone disease. ..
  14. Bone Marrow Fat and Osteopenia in HIV Lipodystrophy
    Jeannie Huang; Fiscal Year: 2006
    ....
  15. Reducing Postpartum Weight Retention Among Low Income, Ethnically Diverse Women
    Lorraine Walker; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  16. Proactive Cessation Intervention with Biomarker Feedback
    JENNIFER MC CLURE; Fiscal Year: 2008
    ..If effective, this treatment strategy could have broad potential as a public health intervention. ..
  17. A New Measure of Nursing Home Care Quality
    Marilyn Rantz; Fiscal Year: 2003
    ..abstract_text> ..
  18. OVERWEIGHT STATUS AFTER CHILDBIRTH
    Lorraine Walker; Fiscal Year: 2003
    ....
  19. PREVENTIVE ONCOLOGY AWARD--SMOKING CESSATION AND WOMEN
    JENNIFER MC CLURE; Fiscal Year: 2003
    ..Such knowledge is important as it may lead to the development of more targeted, and therefore potentially more effective, cessation interventions. ..
  20. Functional Health CAT in Diabetes
    Carolyn Schwartz; Fiscal Year: 2004
    ..abstract_text> ..
  21. An Internet-based intervention for problem drinking
    John Cunningham; Fiscal Year: 2008
    ..The Internet is one promising route for distributing such materials to a large segment of the population...
  22. A Lifestyle Change Program to Prevent Type 2 Diabetes
    Robin Whittemore; Fiscal Year: 2006
    ..3. To explore the reach, adoption, implementation, and maintenance of a lifestyle change program delivered by NPs in primary care settings. ..
  23. AN ALTERNATIVE FOR INCARCERATED SUBSTANCE ABUSERS
    Emil Chiauzzi; Fiscal Year: 2002
    ..If such a program could demonstrate clinical efficacy in field trials with this high-risk population, the commercial potential would be extraordinary. ..
  24. Internet-Based Stress Management for College Students
    Emil Chiauzzi; Fiscal Year: 2004
    ..The final product will be marketed as part of a comprehensive college health website. ..
  25. Quality of Life Intervention in Breast Cancer Survivors
    Karen Dow; Fiscal Year: 2004
    ....
  26. C-CAPRELA: Cervical Cancer Prevention for Latinas
    SCOTT RHODES; Fiscal Year: 2008
    ..developing effective interventions to reduce those disparities, and facilitating intervention delivery." [unreadable] [unreadable] [unreadable]..
  27. Social skills training for aggressive adolescents
    MELISSA DEROSIER; Fiscal Year: 2005
    ..Parent and adolescent evaluations of the PF product will also be gathered. This research will be instrumental in establishing the PF product as an efficacious competitor in the intervention marketplace. ..
  28. Behavioral Intervention for Type 2 Diabetes in Youth
    Alan Delamater; Fiscal Year: 2005
    ..The results from this research will provide the preliminary feasibility and efficacy data needed for the development and submission of a subsequent R18 application. ..
  29. Computerized PAINRelieveIt Protocol for Cancer Pain
    Diana Wilkie; Fiscal Year: 2006
    ..abstract_text> ..
  30. Patterns and Contexts of Club Drug Abuse
    Jeffrey Parsons; Fiscal Year: 2007
    ..Mixed-methods strategies will be used to examine the qualitative and quantitative data together in order to further understand the data and potential implications for intervention development. ..
  31. HIT Support for Safe Nursing Care
    Gail Keenan; Fiscal Year: 2006
    ..h.r.). ..
  32. Shared Medical Records and Chronic Illness Care
    James D Ralston; Fiscal Year: 2010
    ..Results of this study will help inform the development, evaluation and dissemination of patient Web portals designed to support the care of patients with diabetes and multiple co-morbidities. ..
  33. Promoting Healthy Living: Assessing More Effects
    Diane Elliot; Fiscal Year: 2009
    ..We welcome the opportunity to continue our collaborations with other health promotion researchers in address compelling questions and advancing these critical aspects of our nation's health. ..
  34. Multilevel Intervention to Improve Nursing Home Outcomes
    Marilyn Rantz; Fiscal Year: 2009
    ..Similarly, we will observe processes of care delivery before, during and after the multilevel intervention to describe the adoption of the care delivery strategies recommended in the intervention. ..
  35. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2003
    ..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
  36. Technology to Automatically Detect Early Signs of Illness in Senior Housing
    Marilyn J Rantz; Fiscal Year: 2010
    ..Subjects will not use any expensive telehealth equipment or wear any devices. We propose to use this information to detect changes in health status which could indicate an impending acute illness or exacerbation of chronic illness. ..
  37. Usability testing Okay with Asthma V.2.0: An interactive narrataive asthmna progr
    TAMI H contact WYATT; Fiscal Year: 2010
    ..The feasibility testing is guided by Nielsen's usability model and Said's engaging multimedia design model. ..
  38. The Effects of Acute Events on ADL Trajectories of Nursing Home Residents
    Robin L Kruse; Fiscal Year: 2010
    ....
  39. GENOME SCIENCE EDUCATION PROGRAM
    LOUISA STARK; Fiscal Year: 2006
    ..The goal of the GSC is to bridge this knowledge gap, combining Internet-based educational materials with teacher professional development workshops and public courses to increase ..
  40. Improving Mental Health Outcomes of Child Brain Injury
    Shari L Wade; Fiscal Year: 2010
    ..The current project builds upon these investigations by comparing counselor-assisted problem-solving (CAPS) to an internet resource comparison group (IRC)...
  41. Malaria risk reduction among travelers using web-based simulation tool
    LAURIE BETH HARTJES; Fiscal Year: 2010
    ..This program of research addresses NINR objectives by 1) designing/testing an interactive web-based tool to improve self-management, and '2) using evolving technology for on-line data collection and simulation software [56]. ..
  42. Effects of Nicotine on Environmental Stimuli
    Jesse Dallery; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  43. Reducing Obesity & Diabetes in High Risk Youth
    ROBIN G WHITTEMORE; Fiscal Year: 2010
    ..skills training (CST) intervention developed to reduce obesity and T2D risk in minority teens (Tween") and an internet CST program developed for youth with T1D (TeenCope") collaboratively with teens, parents, high school teachers, ..
  44. Tribal Community-Based Prevention of Noise-Induced Hearing Loss and Tinnitus
    William Martin; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  45. Computerized PAINRelievelt for Adult Sickle Cell Disease
    Diana Wilkie; Fiscal Year: 2009
    ..Findings will guide large-scale implementation of this innovation in SC care throughout the USA. ..
  46. A home-based behavioral treatment for cigarette smoking
    Jesse Dallery; Fiscal Year: 2009
    ..The system uses Internet technology to obtain video of smokers providing carbon monoxide samples, which is a simple yet innovative way to ..
  47. Trace Amine Receptor as Medication Development Targets
    ANITA LEWIN; Fiscal Year: 2008
    ..Evaluation of active compounds in other neuromodulatory systems will assist in the determination of selectivity, an important consideration in medication development. [unreadable] [unreadable]..
  48. ADHD: Detection and Service Use
    Regina Bussing; Fiscal Year: 2008
    ..The research team has an extensive track record of success with similar study designs and will use innovative technologies to adhere to an efficient management plan. ..
  49. The Sleep Heart Health Study (SHHS)
    STUART QUAN; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..
  50. Tobacco Cessation via Public Health Dental Clinics
    Judith Gordon; Fiscal Year: 2008
    ..4) The RE-AIM framework will be used to translate and evaluate the intervention in a "real world'' setting. 5) It is a disseminable model that, if effective, can used by public dental clinics throughout the US. ..
  51. First-Time Parent Interactive Parenting Intervention
    Edward Feil; Fiscal Year: 2007
    ..In addition, the meteoric rise of Internet use has created a new avenue for people to communicate and share ideas...
  52. Clinical & Web-based Diet & Activity Counseling for Men
    Kevin Patrick; Fiscal Year: 2006
    ..abstract_text> ..
  53. Impulsivity and Treatments for Relapse Prevention in Smo
    Jesse Dallery; Fiscal Year: 2004
    ..g., cue exposure, contextual factors, nicotine deprivation, drugs of abuse, pharmacotherapies, stress, etc) affect the impulsive choices that lead to or prevent relapse. ..
  54. Effects of Establishing focus in the Medical Interview
    Lynne Robins; Fiscal Year: 2004
    ..If successful, it should be easily disseminated into many practice settings as well as incorporated into professional training. ..
  55. INNOVATIVE JOB PLACEMENT MODEL FOR METHADONE PATIENTS
    Stephen Magura; Fiscal Year: 2004
    ..4) To conduct benefit-cost and cost-effectiveness analyses of the modified IPS vocational rehabilitation program. ..
  56. A home-based behavioral treatment for cigarette smoking
    Jesse Dallery; Fiscal Year: 2004
    ..abstract_text> ..
  57. COMPARATIVE GENOMIC ANALYSIS OF CARDIOVASCULAR GENE REGU
    Inna Dubchak; Fiscal Year: 2003
    ..6) The establishment of an educational program for cardiovascular researchers in the use of genomic databases and tools. ..
  58. DEVELOPMENT OF THE METACYC METABOLIC PATHWAY DATABASE
    Peter Karp; Fiscal Year: 2003
    ....
  59. Supporting School Readiness in Social & literacy Domains
    Edward Feil; Fiscal Year: 2002
    ..abstract_text> ..
  60. Parents' Multimedia Guide to Child Nutrition and Health
    Rebekah Hersch; Fiscal Year: 2003
    ..In Phase II, the effectiveness of the program will be rigorously field tested with parents. ..
  61. INTERNET-BASED INTERVENTIONS FOR YOUTH DISORDERS
    Gregory Clarke; Fiscal Year: 2004
    ..Adapted from Applicant's Abstract): This application proposes to develop and pilot several variants of Internet WWW mental health "self help" skills training sites for children, adolescents and parents...
  62. LEVELS OF CARE AND OUTCOMES IN ALCOHOLISM TREATMENT
    Stephen Magura; Fiscal Year: 2002
    ..Using treatment cost data and outcome results, a cost-effectiveness analysis of matching and mismatching at different Levels of Care will be conducted. ..
  63. Blood lead levels and development of asthma
    Christine Joseph; Fiscal Year: 2002
    ....
  64. Health Communication: NIHL and Tinnitus Prevention
    William Martin; Fiscal Year: 2006
    ..The goal is to decrease the number of cases of preventable noise induced hearing loss and tinnitus, and to promote healthy hearing and good aural communication in the population. ..
  65. Offspring of Maltreated Mothers:Prenatal & Infant Health
    Jennie Noll; Fiscal Year: 2006
    ..The training component will involve extensive independent reading, coursework, seminars, conferences, and concentrated time with mentors. ..
  66. MULTIRISK FACTOR INTERVENTION FOR COLON POLYP PATIENTS
    Karen Emmons; Fiscal Year: 2001
    ..The intervention is suited to the managed care environment, thus increasing its potential generalize ability and disseminability. A process tracking system will enable a detailed cost-effectiveness evaluation. ..
  67. All-Atom Contact Analysis In Improving Structure Quality
    Jane Richardson; Fiscal Year: 2002
    ..abstract_text> ..
  68. Depression in Black and White Adolescent Girls
    Debra Franko; Fiscal Year: 2002
    ....
  69. GROUP MOTIVATIONAL INTERVENTION IN DRUG ABUSE TREATMENT
    Stephen Magura; Fiscal Year: 2002
    ..Because even a brief group therapy may add to treatment costs, it is important6 to determine the cost per patient for each additional unit of positive outcome achieved (assuming outcomes improve). ..
  70. HORMONE REPLACEMENT THERAPY AND BREAST CANCER
    Patricia Carney; Fiscal Year: 2004
    ..abstract_text> ..
  71. Antecedents of Drug Abuse and Dependence
    Kate Fothergill; Fiscal Year: 2003
    ..The use of hierarchical regression analyses and multi-level analyses will allow for examination of both the direct and indirect effects of these factors on adult drug abuse and dependence. ..
  72. Feasibility of a Theory-Based Online Hip Fracture Resource Center for Caregivers
    Eun Shim Nahm; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  73. Combining Computational and Experimentation to Interrogate NF-kappaB Signaling
    Markus Covert; Fiscal Year: 2008
    ..We propose to use computer modeling and experiments to help us understand the NF-kappaB signaling network and its role in cancer development, particularly with regard to diffuse large B cell lymphomas. ..
  74. Preventing Type 2 Diabetes in At-Risk Youth
    Margaret Grey; Fiscal Year: 2006
    ..It is expected that this important and timely study will provide valuable information to help youth manage obesity, and potentially prevent T2DM and its long-term physical and psychosocial complications. [unreadable] [unreadable]..
  75. Counseling for Overweight Women for Diet and Activity
    Kevin Patrick; Fiscal Year: 2005
    ..The PACE+ intervention is particularly innovative in that three components - computer, primary care provider counseling, and an extended home-based intervention - are unified through a common theoretical framework. ..
  76. Interactive Program to Manage and Prevent Back Pain
    A Irvine; Fiscal Year: 2007
    ..The Internet/CD-Rom training program will include a Back Pain Assessment Tool, feedback and recommendations, and assistance ..
  77. Diffusing Sun Safe Policies and Environments to Schools
    David Buller; Fiscal Year: 2008
    ..On-site observations of sun protection policies, environmental features, and employee clothing will validate principal reports. [unreadable] [unreadable]..
  78. Stress, Coping, and Well-Being of Custodial Grandparents
    Gregory Smith; Fiscal Year: 2003
    ..Aim 5 is to archive the data for eventual use by other researchers; The findings of this study will inform the development of interventions tailored to assist custodial grandparents and their families. ..
  79. Stigma & Behavioral Health in Urban Employers from China & US
    Patrick Corrigan; Fiscal Year: 2007
    ..Data from this study will be especially important for the development of future stigma-change programs. ..
  80. PRIDE: Program to Reduce Incontinence by Diet & Exercise
    Rena Wing; Fiscal Year: 2007
    ..If effective in womenwith incontinence, the methods and strategies of this innovative motivationally-focusedmaintenance intervention can beexamined n other obese populations. ..
  81. Stepped Care for Depression and Musculoskeletal Pain
    Kurt Kroenke; Fiscal Year: 2007
    ..Longitudinal assessment of the nondepressed cohort will establish the frequency and risk factors for incident depression. ..
  82. INTERNET BASED SMOKING EDUCATION FOR COLLEGE STUDENTS
    Emil Chiauzzi; Fiscal Year: 2003
    ..Finally, we will gather satisfaction data from participating students and acceptance feedback from health professionals at participating colleges. ..
  83. Prevention of Weight Gain in Young Adults
    Rena Wing; Fiscal Year: 2009
    ..This approach shows promise for reducing weight gain and thereby improving long-term cardiovascular health. (End of Abstract) ..
  84. Personalized Feedback Intervention for Marijuana Use
    Christine Lee; Fiscal Year: 2005
    ..The primary aim of the current project is to document the efficacy of an internet-based personalized normative feedback (PNF) intervention, compared to an assessment-only condition, in preventing ..
  85. Toolkits-Will Implementing an Evidence-Based Curriculum Improve Group Counseling?
    Adam C Brooks; Fiscal Year: 2010
    ..abstract_text> ..
  86. Long-Term Weight Loss Maintenance
    Rena Wing; Fiscal Year: 2007
    ..Such information is important for providing an accurate picture to those individuals seeking to lose weight of what it takes to be a successful weight loss maintainer. ..
  87. College Administrator Website for Alcohol Programming
    Emil Chiauzzi; Fiscal Year: 2006
    ..The goal is a final product that will help colleges and universities develop task forces so that comprehensive, cohesive alcohol prevention programming replaces piecemeal and reactive program development. ..
  88. INTERNET-BASED ALCOHOL INFORMATION FOR COLLEGE STUDENTS
    Emil Chiauzzi; Fiscal Year: 2002
    ..current application combines state-of-the-art knowledge about tailoring preventive strategies with advances in Internet- based technologies...
  89. National Nutrient Databank Conference
    Phyllis Stumbo; Fiscal Year: 2004
    ..Scholarships are requested to increase participation by minority and disadvantaged students. ..
  90. Pathway Prediction and Assessment Integrating Multiple Evidence Types
    Peter Karp; Fiscal Year: 2009
    ..We will search the MetaCyc reaction space (comprising almost 6000 reactions) for novel subpathways, explicitly constraining our search using organism-specific evidence (i.e., homology, experimental evidence, etc.) at each step. ..
  91. GENETIC EDUCATION FOR NATIVE AMERICANS
    Linda Burhansstipanov; Fiscal Year: 2003
    ..The overall goal of this application is to develop culturally acceptable materials providing Native American students with information so that they can make informed decisions about genetic issues. ..
  92. Using the Internet to Improve Patient's Self-Management of Chronic Illness
    Deborah Miller; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): Title: Using the Internet to Improve Patient's Self-Management of Chronic Illness Background: Telemedicine has been defined as the use of electronic information and communication technologies to ..
  93. MouseCyc: A Biochemical Pathway Database for the Mouse
    Carol Bult; Fiscal Year: 2008
    ..Relevance to Public Health The MouseCyc database will serve as a publicly accessible internet resource that the scientific community will use to analyze mouse genetic and genomic data in the context of ..
  94. Palliative Oxygen for the Relief of Breathlessness
    Amy Abernethy; Fiscal Year: 2007
    ..The results will also advance a long-standing international debate about the role of palliative oxygen for intractable dyspnea and it's funding. [unreadable] [unreadable] [unreadable]..
  95. HIV Among Rural Latino Gay Men and MSM in the Southeast
    SCOTT RHODES; Fiscal Year: 2007
    ..Study findings also will help shape new multilevel intervention approaches and strategies to reduce the disproportionate HIV/AIDS disease burden of Latino men. [unreadable] [unreadable] [unreadable]..
  96. Trabajando Juntos: Working for Health Disparity Reduction among Latinos
    SCOTT RHODES; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  97. Therapeutic Computer Activity Intervention in Alzheimer's Disease
    Sunghee Tak; Fiscal Year: 2009
    ..Using a standardized videotape-recording protocol, data collection will occur at baseline, treatment, and one-week follow-up. A mixed model ANOVA (time as a repeated factor) will be used to assess changes in agitated behaviors. ..
  98. Robust Software Components for Model Organism Databases
    Peter Karp; Fiscal Year: 2003
    ..Although Pathway Tools is particularly well adapted to microbial MODs, one goal of this application is to adapt the metabolic pathway part of Pathway Tools to work with MODs for higher organisms. ..