computer assisted signal processing

Summary

Summary: Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.

Top Publications

  1. ncbi A robust, real-time control scheme for multifunction myoelectric control
    Kevin Englehart
    Department of Biomedical Engineering, University of New Brunswick, 25 Dineen Drive, Fredericton, NB E3B5A3, Canada
    IEEE Trans Biomed Eng 50:848-54. 2003
  2. ncbi Localization of brain electrical activity via linearly constrained minimum variance spatial filtering
    B D Van Veen
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison 53706, USA
    IEEE Trans Biomed Eng 44:867-80. 1997
  3. pmc Mapping the signal-to-noise-ratios of cortical sources in magnetoencephalography and electroencephalography
    Daniel M Goldenholz
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, USA
    Hum Brain Mapp 30:1077-86. 2009
  4. ncbi Cramér-Rao bounds: an evaluation tool for quantitation
    S Cavassila
    Laboratoire RMN, CNRS UMR 5012, UCB Lyon I CPE, Villeurbanne, France
    NMR Biomed 14:278-83. 2001
  5. ncbi Properties of the ballistocardiogram artefact as revealed by EEG recordings at 1.5, 3 and 7 T static magnetic field strength
    Stefan Debener
    Medical Research Council Institute of Hearing Research, Royal South Hants Hospital, Southampton, SO14 OYG, United Kingdom
    Int J Psychophysiol 67:189-99. 2008
  6. ncbi A multivariate, spatiotemporal analysis of electromagnetic time-frequency data of recognition memory
    E Duzel
    Department of Neurology II, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Neuroimage 18:185-97. 2003
  7. ncbi Extracting information from neuronal populations: information theory and decoding approaches
    Rodrigo Quian Quiroga
    Department of Engineering, University of Leicester, Leicester, LE1 7RH, UK
    Nat Rev Neurosci 10:173-85. 2009
  8. ncbi Automatic classification of heartbeats using ECG morphology and heartbeat interval features
    Philip de Chazal
    Department of Electronic and Electrical Engineering, University College Dublin, Belfield, Dublin 4, Ireland
    IEEE Trans Biomed Eng 51:1196-206. 2004
  9. ncbi A comparison of surface and intramuscular myoelectric signal classification
    Levi J Hargrove
    Institute of Biomedical Engineering, Department of Electrical and Computer Engineering, University of New Brunswick, P O Box 4400, Fredericton, NB E3B 5A3, Canada
    IEEE Trans Biomed Eng 54:847-53. 2007
  10. ncbi Natural frequencies of human corticothalamic circuits
    Mario Rosanova
    Department of Clinical Sciences, Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci 29:7679-85. 2009

Detail Information

Publications295 found, 100 shown here

  1. ncbi A robust, real-time control scheme for multifunction myoelectric control
    Kevin Englehart
    Department of Biomedical Engineering, University of New Brunswick, 25 Dineen Drive, Fredericton, NB E3B5A3, Canada
    IEEE Trans Biomed Eng 50:848-54. 2003
    ..Finally, minimal storage capacity is required, which is an important factor in embedded control systems...
  2. ncbi Localization of brain electrical activity via linearly constrained minimum variance spatial filtering
    B D Van Veen
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison 53706, USA
    IEEE Trans Biomed Eng 44:867-80. 1997
    ..The effect on the algorithm of covariance matrix estimation, correlation between sources, and choice of reference is discussed. Simulated and measured data is used to illustrate the efficacy of the approach...
  3. pmc Mapping the signal-to-noise-ratios of cortical sources in magnetoencephalography and electroencephalography
    Daniel M Goldenholz
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, USA
    Hum Brain Mapp 30:1077-86. 2009
    ..Clinically, SNR maps in a patient explained differential sensitivity of MEG and EEG in detecting epileptic activity. Our results emphasize the benefits of recording MEG and EEG simultaneously...
  4. ncbi Cramér-Rao bounds: an evaluation tool for quantitation
    S Cavassila
    Laboratoire RMN, CNRS UMR 5012, UCB Lyon I CPE, Villeurbanne, France
    NMR Biomed 14:278-83. 2001
    ..The influence of constraints (chemical prior knowledge) on spectral parameters of the peaks of doublets is demonstrated and the inherent benefits for quantitation are shown. Abbreviations used: CRB Cramér-Rao lower bounds..
  5. ncbi Properties of the ballistocardiogram artefact as revealed by EEG recordings at 1.5, 3 and 7 T static magnetic field strength
    Stefan Debener
    Medical Research Council Institute of Hearing Research, Royal South Hants Hospital, Southampton, SO14 OYG, United Kingdom
    Int J Psychophysiol 67:189-99. 2008
    ..This is summarized in a preliminary BCG model that may help to explain recent inconsistencies regarding the usefulness of ICA for BCG removal. It may also guide the future development of more advanced BCG removal procedures...
  6. ncbi A multivariate, spatiotemporal analysis of electromagnetic time-frequency data of recognition memory
    E Duzel
    Department of Neurology II, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Neuroimage 18:185-97. 2003
    ....
  7. ncbi Extracting information from neuronal populations: information theory and decoding approaches
    Rodrigo Quian Quiroga
    Department of Engineering, University of Leicester, Leicester, LE1 7RH, UK
    Nat Rev Neurosci 10:173-85. 2009
    ..Such population analysis can give us more information about how neurons encode stimulus features than traditional single-cell studies...
  8. ncbi Automatic classification of heartbeats using ECG morphology and heartbeat interval features
    Philip de Chazal
    Department of Electronic and Electrical Engineering, University College Dublin, Belfield, Dublin 4, Ireland
    IEEE Trans Biomed Eng 51:1196-206. 2004
    ..For the VEB class, the sensitivity was 77.7%, the positive predictivity was 81.9%, and the false positive rate was 1.2%. These results are an improvement on previously reported results for automated heartbeat classification systems...
  9. ncbi A comparison of surface and intramuscular myoelectric signal classification
    Levi J Hargrove
    Institute of Biomedical Engineering, Department of Electrical and Computer Engineering, University of New Brunswick, P O Box 4400, Fredericton, NB E3B 5A3, Canada
    IEEE Trans Biomed Eng 54:847-53. 2007
    ..Impressive classification accuracy (97%) could be achieved by optimally selecting only three channels of surface MES...
  10. ncbi Natural frequencies of human corticothalamic circuits
    Mario Rosanova
    Department of Clinical Sciences, Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci 29:7679-85. 2009
    ..The natural frequency can be directly measured in virtually any area of the cerebral cortex and may represent a straightforward and flexible way to probe the state of human thalamocortical circuits at the patient's bedside...
  11. ncbi Wavelets in bioinformatics and computational biology: state of art and perspectives
    Pietro Lio
    Department of Zoology, University of Cambridge, UK
    Bioinformatics 19:2-9. 2003
    ..Wavelets are more efficient and faster than Fourier methods in capturing the essence of data. Nowadays there is a growing interest in using wavelets in the analysis of biological sequences and molecular biology-related signals...
  12. ncbi Wavelet entropy: a new tool for analysis of short duration brain electrical signals
    O A Rosso
    Facultad de Ciencias Exactas y Naturales, Instituto de Calculo, Universidad de Buenos Aires, Pabellon II, Ciudad Universitaria, 1428, Buenos Aires, Argentina
    J Neurosci Methods 105:65-75. 2001
    ..Further, specific quantifiers were derived to characterize how stimulus affects electrical events in terms of frequency synchronization (tuning) in the event related potentials...
  13. ncbi Functional electrical stimulation for neuromuscular applications
    P Hunter Peckham
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA
    Annu Rev Biomed Eng 7:327-60. 2005
    ....
  14. ncbi A wavelet-based ECG delineator: evaluation on standard databases
    Juan Pablo Martinez
    Communications Technology Group, Aragon Institute of Engineering Research, University of Zaragoza, Maria de Luna, 1, 50015 Zaragoza, Spain
    IEEE Trans Biomed Eng 51:570-81. 2004
    ....
  15. ncbi P wave signal-averaged electrocardiography to identify risk for atrial fibrillation
    Dawood Darbar
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pacing Clin Electrophysiol 25:1447-53. 2002
    ..Combining P wave duration with other predictors for AF improves the diagnostic value of P wave SAECG...
  16. ncbi Adaptive time-frequency parametrization in pharmaco EEG
    Piotr J Durka
    Laboratory of Medical Physics, Institute of Experimental Physics, Warsaw University, ul Hoza 69, 00 681 Warszawa, Poland
    J Neurosci Methods 117:65-71. 2002
    ..The observed decrease of frequency of the SWA under the influence of sleep-inducing drugs gives an example of an effect elusive to classical methodology...
  17. ncbi Phase synchronization measurements using electroencephalographic recordings: what can we really say about neuronal synchrony?
    Ramon Guevara
    Abdus Salam ICTP, Strada Costiera 11, 34100, Miaramare, Trieste, Italy
    Neuroinformatics 3:301-14. 2005
    ....
  18. ncbi Texture-based classification of atherosclerotic carotid plaques
    C I Christodoulou
    Cyprus Institute of Neurology and Genetics, P O Box 3462, 1683 Nicosia, Cyprus
    IEEE Trans Med Imaging 22:902-12. 2003
    ..This group of patients may benefit from a carotid endarterectomy whereas other patients may be spared from an unnecessary operation...
  19. ncbi The time course of visual word recognition as revealed by linear regression analysis of ERP data
    O Hauk
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    Neuroimage 30:1383-400. 2006
    ....
  20. ncbi Parameter-optimized digital holographic microscope for high-resolution living-cell analysis
    Daniel Carl
    Laboratory of Biophysics, University of Munster, Robert Koch Strasse 45, D 48129 Munster, Germany
    Appl Opt 43:6536-44. 2004
    ..The lateral and the axial resolutions of the system are discussed and quantified by application to technical objects and to living cells...
  21. ncbi Visually guided movements suppress subthalamic oscillations in Parkinson's disease patients
    Ramin Amirnovin
    Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114 3117, USA
    J Neurosci 24:11302-6. 2004
    ..One possible explanation for these observations is that the increased cortical drive associated with movement preparation and execution leads to a transient dampening of STN oscillations, hence facilitating movement...
  22. ncbi A new approach to neuroimaging with magnetoencephalography
    Arjan Hillebrand
    Wellcome Trust Laboratory for MEG Studies, Neurosciences Research Institute, Aston University, Birmingham, United Kingdom
    Hum Brain Mapp 25:199-211. 2005
    ..What is more, MEG beamformer analysis facilitates the study of these complex interactions within cortical networks that are involved in both sensory-motor and cognitive processes...
  23. ncbi CPR artifact removal from human ECG using optimal multichannel filtering
    S O Aase
    Stavanger University College, Department of Electrical and Computer Engineering, Norway
    IEEE Trans Biomed Eng 47:1440-9. 2000
    ..The success of the proposed method is demonstrated through graphic examples, SNR, and rhythm classification evaluations...
  24. ncbi Sampling, noise-reduction and amplitude estimation issues in surface electromyography
    E A Clancy
    Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609
    J Electromyogr Kinesiol 12:1-16. 2002
    ..Theoretical and experimental research related to each of the above topics is reviewed and the current recommended practices are described...
  25. ncbi Artifact correction and source analysis of early electroencephalographic responses evoked by transcranial magnetic stimulation over primary motor cortex
    Vladimir Litvak
    Faculty of Biomedical Engineering, Technion Israel Institute of Technology, Haifa, Israel
    Neuroimage 37:56-70. 2007
    ..The methodology developed in the present study paves the way for the detailed study of early responses to TMS in a wide variety of brain areas...
  26. ncbi Single versus multiple probe blocks of P300-based concealed information tests for self-referring versus incidentally obtained information
    J P Rosenfeld
    Department of Psychology, Northwestern University, Evanston, IL, USA
    Biol Psychol 74:396-404. 2007
    ..In contrast, in the multiple probe (and category) block, rare probes, rare targets and frequent irrelevant items were repeatedly presented in a Bernoulli series within one block...
  27. ncbi Nonlinear multivariate analysis of neurophysiological signals
    Ernesto Pereda
    Department of Basic Physics, College of Physics and Mathematics, University of La Laguna, Avda Astrofísico Fco Sánchez s n, 38205 La Laguna, Tenerife, Spain
    Prog Neurobiol 77:1-37. 2005
    ..Finally, we illustrate the use of multivariate surrogate data test for the assessment of the strength (strong or weak) and the type (linear or nonlinear) of interdependence between neurophysiological signals...
  28. pmc Sensory-evoked gamma oscillations in chronic schizophrenia
    Kevin M Spencer
    Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 63:744-7. 2008
    ..We investigated these issues by examining the VGO and AGO in chronic schizophrenic (SZ) and matched healthy control (HC) subjects...
  29. ncbi Interaction dynamics of neuronal oscillations analysed using wavelet transforms
    Xiaoli Li
    Cercia, School of Computer Science, The University of Birmingham, Birmingham B15 2TT, UK
    J Neurosci Methods 160:178-85. 2007
    ..The results of this real case study show that the computational tool can successfully analyse and quantify the temporal interactions between neuronal oscillators and could be employed to investigate the mechanisms underlying epilepsy...
  30. pmc Regional differences in the sensitivity of MEG for interictal spikes in epilepsy
    Geertjan Huiskamp
    Department of Neurology and Clinical Neurophysiology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, F02 230 Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Brain Topogr 23:159-64. 2010
    ....
  31. ncbi CPR artifact removal in ventricular fibrillation ECG signals using Gabor multipliers
    Tobias Werther
    Faculty of Mathematics, University of Vienna, A 1090 Vienna, Austria
    IEEE Trans Biomed Eng 56:320-7. 2009
    ..Removing motion artifacts in ECG allows for uninterrupted rhythm analysis and reduces "hands-off" time during resuscitation...
  32. ncbi Comparative study of morphological and time-frequency ECG descriptors for heartbeat classification
    Ivaylo Christov
    Centre of Biomedical Engineering Prof Ivan Daskalov, Bulgarian Academy of Sciences, Acad G Bonchev Str Bl 105, 1113 Sofia, Bulgaria
    Med Eng Phys 28:876-87. 2006
    ....
  33. pmc An ERP study of emotional face processing in the adult and infant brain
    Jukka M Leppanen
    Human Information Processing Laboratory, Department of Psychology, University of Tampere, Tampere, FIN 33014 Finland
    Child Dev 78:232-45. 2007
    ....
  34. ncbi Wavelet transform-based QRS complex detector
    S Kadambe
    Information Sciences Laboratory, HRL Laboratories, Malibu CA 90265, USA
    IEEE Trans Biomed Eng 46:838-48. 1999
    ..For multiform premature ventricular contractions, bigeminy, and couplets tapes, the Dy WT-based detector exhibited excellent performance...
  35. ncbi Independent component approach to the analysis of EEG and MEG recordings
    R Vigário
    Laboratory of Computer and Information Science, Helsinki University of Technology, HUT, Finland
    IEEE Trans Biomed Eng 47:589-93. 2000
    ..In addition, ICA has been applied to the analysis of brain signals evoked by sensory stimuli. This paper reviews our recent results in this field...
  36. ncbi Combined wavelet transformation and radial basis neural networks for classifying life-threatening cardiac arrhythmias
    A S Al-Fahoum
    SPIRE Laboratory, Electrical Engineering and Computer Science Department, Milwaukee, WI 53201, USA
    Med Biol Eng Comput 37:566-73. 1999
    ..Utilising the Daubechies wavelet transform, an overall correct classification of 97.5% is obtained, with 100% correct classification for both ventricular fibrillation and ventricular tachycardia...
  37. ncbi Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources
    Cornelis J Stam
    Department of Clinical Neurophysiology, VU University Medical Center, Amsterdam, The Netherlands
    Hum Brain Mapp 28:1178-93. 2007
    ....
  38. ncbi Drosophila courtship song cycles in normal and period mutant males revisited
    C P Kyriacou
    Department of Genetics, University of Leicester, U K
    Behav Genet 20:617-44. 1990
    ..We discuss the implications of these findings and of some recently reported results that have challenged the existence of rhythmicity in Drosophila songs...
  39. ncbi Commonalities and differences among vectorized beamformers in electromagnetic source imaging
    M X Huang
    Center for Functional Brain Imaging, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Brain Topogr 16:139-58. 2004
    ..Excellent agreement is also found between the results of our beamformer and the known neurophysiology of the median-nerve MEG response...
  40. ncbi Digital pathology: DICOM-conform draft, testbed, and first results
    Ralf Zwönitzer
    Department of Biometry and Medical Informatics, Otto von Guericke University, Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Comput Methods Programs Biomed 87:181-8. 2007
    ..The results showed that digital pathology is feasible but strong efforts by users and vendors are still necessary to integrate Digital Pathology into existing information systems...
  41. ncbi P300 and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4s229A, MSC 1379, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 60:1158-67. 2003
    ....
  42. ncbi Identification of rhythmic subsystems in the circadian cycle of crassulacean acid metabolism under thermoperiodic perturbations
    Andreas Bohn
    Institute of Applied Physics, Darmstadt University of Technology, D 64289 Darmstadt, Germany
    Biol Chem 384:721-8. 2003
    ....
  43. ncbi Auditory space-time receptive field dynamics revealed by spherical white-noise analysis
    R L Jenison
    Departments of Psychology, and Waisman Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 21:4408-15. 2001
    ..Our results show that approximately 14% of AI neurons evidence significant space-time interaction (inseparability)...
  44. ncbi The principles of software QRS detection
    Bert Uwe Köhler
    Department of Electrical Engineering, Biomedical Electronics Group, Berlin University of Technology
    IEEE Eng Med Biol Mag 21:42-57. 2002
  45. ncbi Dynamic visualization of lung sounds with a vibration response device: a case series
    R Phillip Dellinger
    Division of Cardiovascular Disease and Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
    Respiration 75:60-72. 2008
    ..The field of computer-assisted mapping of lung sounds is constantly evolving and several devices have been developed in this field...
  46. ncbi Small-world networks and epilepsy: graph theoretical analysis of intracerebrally recorded mesial temporal lobe seizures
    S C Ponten
    Department of Clinical Neurophysiology, VU University Medical Centre, 1007 MB Amsterdam, The Netherlands
    Clin Neurophysiol 118:918-27. 2007
    ..We tested the hypothesis that real functional brain networks during seizures display small-world features, using intracerebral recordings of mesial temporal lobe seizures...
  47. ncbi A new method to identify multiple sources of oscillatory activity from magnetoencephalographic data
    Ole Jensen
    Brain Research Unit, Helsinki University of Technology, Helsinki, FIN 02015 HUT, Finland
    Neuroimage 15:568-74. 2002
    ..The main advantage of the proposed method is that it provides an efficient approach for simultaneous estimation of multiple sources of oscillatory activity in the same frequency band...
  48. ncbi Electrocardiogram signal preprocessing for automatic detection of QRS boundaries
    I K Daskalov
    Centre of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia
    Med Eng Phys 21:37-44. 1999
    ..Examples of detection of QRS onset and offset points and a comparison with observer markings are presented for the assessment of preprocessing efficiency and detection consistency...
  49. ncbi Recognition of motor imagery electroencephalography using independent component analysis and machine classifiers
    Chih I Hung
    Institute of Radiological Sciences, National Yang Ming University, Taipei, ROC, Taiwan
    Ann Biomed Eng 33:1053-70. 2005
    ..65, .60, .62, and .64 to .74, .76, .80 and .81, respectively...
  50. ncbi A nonlinear adaptive method of elimination of power line interference in ECG signals
    Alireza K Ziarani
    Edward S Rogers Sr Department of Electrical and Computer Engineering, University of Toronto, ON, Canada
    IEEE Trans Biomed Eng 49:540-7. 2002
    ..The proposed method presents a simple and robust structure which complies with practical constraints involved in the problem such as low computational resource availability and low sampling frequency...
  51. ncbi Wavelength-scanning digital interference holography for tomographic three-dimensional imaging by use of the angular spectrum method
    Lingfeng Yu
    Department of Physics, University of South Florida, Tampa, Florida 33620, USA
    Opt Lett 30:2092-4. 2005
    ..Experiments are performed to demonstrate the effectiveness of the method...
  52. ncbi A comparison of adaptive and nonadaptive filters for reduction of power line interference in the ECG
    P S Hamilton
    Department of Electrical Engineering, Lafayette College, Easton, PA 18042, USA
    IEEE Trans Biomed Eng 43:105-9. 1996
    ..37 bits per sample (bps) lower than the unfiltered signal. The nonadaptive 60-Hz filter produced an average entropy decrease of 0.08 bps relative to the unfiltered ECG...
  53. ncbi Computer-aided tumor detection in endoscopic video using color wavelet features
    Stavros A Karkanis
    Realtime Systems and Image Analysis Group, Department of Informatics and Telecommunications, University of Athens, Greece
    IEEE Trans Inf Technol Biomed 7:141-52. 2003
    ..The performance in the detection of abnormal colonic regions corresponding to adenomatous polyps has been estimated high, reaching 97% specificity and 90% sensitivity...
  54. ncbi Maturation of human central auditory system activity: separating auditory evoked potentials by dipole source modeling
    Curtis Ponton
    Electrophysiology Laboratory, House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA
    Clin Neurophysiol 113:407-20. 2002
    ..Thus, the purpose of this study was to evaluate central auditory system maturation based dipole modeling of multi-electrode long-latency AEPs recordings...
  55. ncbi A network model of perceptual suppression induced by transcranial magnetic stimulation
    Yoichi Miyawaki
    RIKEN Brain Science Institute, Saitama 351 0198, Japan
    Neural Comput 16:309-31. 2004
    ..These results agree well with typical experimental data for occipital TMS and support the conclusion that dynamical interaction in a neural population plays an important role in TMS-induced perceptual suppression...
  56. ncbi Phase-coupling of theta-gamma EEG rhythms during short-term memory processing
    B Schack
    Institute of Medical Statistics, Computer Science and Documentation, University of Jena, Jahnstr 3, D 07740, Jena, Germany
    Int J Psychophysiol 44:143-63. 2002
    ..This finding is interpreted as an EEG aspect of the functional linking between the prefrontal areas and the G.cinguli (as part of the limbic system), which are both extremely important for memory functions...
  57. ncbi Suppression of interference and artifacts by the Signal Space Separation Method
    Samu Taulu
    Elekta Neuromag Oy, Helsinki, Finland
    Brain Topogr 16:269-75. 2004
    ..When used with properly designed sensor array, SSS does not affect the morphology or the signal-to-noise ratio of the interesting signals...
  58. ncbi Automatic detection of the electrocardiogram T-wave end
    I K Daskalov
    Centre of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria
    Med Biol Eng Comput 37:348-53. 1999
    ..Automatic detection methods are in fact faced with 'high-gain' data, as high-resolution analogue-to-digital conversion is already widely used...
  59. ncbi A wavelet transform-based ECG compression method guaranteeing desired signal quality
    J Chen
    Graduate School of Information Systems, University of Electro Communications, Chofu, Tokyo, Japan
    IEEE Trans Biomed Eng 45:1414-9. 1998
    ....
  60. ncbi The Berlin Brain--Computer Interface: accurate performance from first-session in BCI-naïve subjects
    Benjamin Blankertz
    Machine Learning Laboratory, Technical University of Berlin, Berlin, Germany
    IEEE Trans Biomed Eng 55:2452-62. 2008
    ..Thus, 12 out of 14 BCI-novices had significant above-chance level performances without any subject training even in the first session, as based on an optimized EEG analysis by advanced machine-learning algorithms...
  61. ncbi Digital holographic microscopy: a noninvasive contrast imaging technique allowing quantitative visualization of living cells with subwavelength axial accuracy
    Pierre Marquet
    Department of Physiology, University of Lausanne, CH 1005 Lausanne, Switzerland
    Opt Lett 30:468-70. 2005
    ..These DHM images are compared with those obtained by use of the widely used phase contrast and Nomarski differential interference contrast techniques...
  62. ncbi Heritability of "small-world" networks in the brain: a graph theoretical analysis of resting-state EEG functional connectivity
    Dirk J A Smit
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Hum Brain Mapp 29:1368-78. 2008
    ..It is asserted that C, L, and a small-world organization are viable markers of genetic differences in brain organization...
  63. ncbi Statistical flattening of MEG beamformer images
    Gareth R Barnes
    The Wellcome Trust Laboratory for MEG Studies, Neurosciences Research Institute, Aston University, Birmingham B4 7ET, United Kingdom
    Hum Brain Mapp 18:1-12. 2003
    ..Per-voxel threshold estimates, based on the voxels extent (or cluster size) in flattened space, provide accurate corrected false positive error rates for these highly inhomogeneously smooth images...
  64. pmc Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation
    Benjamin R Biedermann
    Lehrstuhl fur BioMolekulare Optik, Fakultat fur Physik, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Opt Lett 33:2556-8. 2008
    ....
  65. pmc Re-entrant projections modulate visual cortex in affective perception: evidence from Granger causality analysis
    Andreas Keil
    NIMH Center for the Study of Emotion and Attention, University of Florida, Gainesville, FL, USA
    Hum Brain Mapp 30:532-40. 2009
    ..Thus, we provide evidence for re-entrant signal flow during emotional perception, which originates from higher tiers and enters lower tiers of visual cortex...
  66. pmc Spike train analysis toolkit: enabling wider application of information-theoretic techniques to neurophysiology
    David H Goldberg
    Laboratory of Neuroinformatics D 404 and Department of Physiology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA
    Neuroinformatics 7:165-78. 2009
    ..org , maintained as a resource for the computational neuroscience and neuroinformatics communities. Use cases drawn from somatosensory and gustatory neurophysiology, and community use of STAToolkit, demonstrate its utility and scope...
  67. ncbi Spatio-temporal dynamics prior to neocortical seizures: amplitude versus phase couplings
    Mario Chavez
    laboratoire de neurosciences cognitives et imagerie cérébrale LENA, CNRS UPR 640 Hôpital de la Salpêtrière, Paris, 76651 Cedex 13, France
    IEEE Trans Biomed Eng 50:571-83. 2003
    ..The possibility of forecasting the onset of seizures has important implications for a better understanding, diagnosis and a potential treatment of the epilepsy...
  68. ncbi Automatic sorting for multi-neuronal activity recorded with tetrodes in the presence of overlapping spikes
    Susumu Takahashi
    Department of Computer Science, Graduate School of Science and Technology, Keio University, Yokohama 223 8522, Japan
    J Neurophysiol 89:2245-58. 2003
    ..The present method provides insights into the local circuit bases of excitatory and inhibitory interactions among neighboring neurons...
  69. pmc Real-time polarization-sensitive optical coherence tomography data processing with parallel computing
    Gangjun Liu
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, California 92612, USA
    Appl Opt 48:6365-70. 2009
    ..The real-time 2D and 3D polarization-sensitive imaging of chicken muscle and pig tendon is also demonstrated...
  70. ncbi Time Domain Parameters as a feature for EEG-based Brain-Computer Interfaces
    Carmen Vidaurre
    Machine Learning Group, Berlin Institute of Technology, Franklinstr 28 29, 10587 Berlin, Germany
    Neural Netw 22:1313-9. 2009
    ..We compare Time Domain Parameters with logarithmic band power in subject-specific bands and show that these features are advantageous in this situation as well...
  71. ncbi Abnormal fronto-parietal coupling of brain rhythms in mild Alzheimer's disease: a multicentric EEG study
    Claudio Babiloni
    Dip Fisiologia Umana e Farmacologia, University La Sapienza Rome, Italy
    Eur J Neurosci 19:2583-90. 2004
    ..These results suggest that mild AD is characterized by an abnormal fronto-parietal coupling of the dominant human cortical rhythm at 8-10.5 Hz...
  72. pmc Cancellation of EEG and MEG signals generated by extended and distributed sources
    Seppo P Ahlfors
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Charlestown, 02129, USA
    Hum Brain Mapp 31:140-9. 2010
    ..Furthermore, the selective cancellation may be used to explain some observed differences between EEG and MEG in terms of focal vs. widespread cortical activity...
  73. ncbi Quantifying statistical interdependence by message passing on graphs-part II: multidimensional point processes
    J Dauwels
    Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neural Comput 21:2203-68. 2009
    ..Numerical results suggest that SES is significantly more sensitive to perturbations in EEG synchrony than a large variety of classical synchrony measures...
  74. ncbi Myoelectric signal processing for control of powered limb prostheses
    P Parker
    Institute of Biomedical Engineering, Department of Electrical and Computer Engineering, University of New Brunswick, 15 Dineen Drive, P O Box 4400, Fredericton, NB, Canada E3B 5A3
    J Electromyogr Kinesiol 16:541-8. 2006
    ..The paper demonstrates that considerable progress has been made in providing clients with useful and reliable myoelectric communication channels, and that exciting work and developments are on the horizon...
  75. pmc The design and testing of a novel mechanomyogram-driven switch controlled by small eyebrow movements
    Natasha Alves
    Bloorview Research Institute, Bloorview Kids Rehab, Toronto, Ontario, Canada
    J Neuroeng Rehabil 7:22. 2010
    ..In this study, we describe the design and demonstrate the performance of a binary switch controlled by mechanomyogram (MMG) signals recorded from the frontalis muscle during eyebrow movements...
  76. ncbi Prior intention can locally tune inhibitory processes in the primary motor cortex: direct evidence from combined TMS-EEG
    M Bonnard
    Mediterranean Institute of Cognitive Neuroscience, UMR 6193, CNRS University of Aix Marseille, Marseille Cedex 20, France
    Eur J Neurosci 30:913-23. 2009
    ..In conclusion, prior intention can tune the excitability of M1. When subjects prepare to resist a TMS-evoked movement, the anticipatory processes cause a decreased cortical excitability by locally increasing the inhibitory processes...
  77. ncbi Use of MMG signals for the control of powered orthotic devices: development of a rectus femoris measurement protocol
    Michele Gabrio Antonelli
    Dipartimento di Ingegneria Meccanica, Energetica e Gestionale, Universita degli Studi di L Aquila, Roio Poggio, Italy
    Assist Technol 21:1-12. 2009
    ..This conclusion is supported by the qualitative characteristics of the mean rectus femoris MMG power spectral densities obtained using 25 averages...
  78. pmc Time-series analysis for rapid event-related skin conductance responses
    Dominik R Bach
    Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    J Neurosci Methods 184:224-34. 2009
    ..We suggest our approach provides greater flexibility in analysing SCRs than existing methods...
  79. ncbi Orientation-tuned FMRI adaptation in human visual cortex
    Fang Fang
    Department of Psychology, University of Minnesota, Minneapolis, 55455, USA
    J Neurophysiol 94:4188-95. 2005
    ..In addition to supporting the existence of adaptable orientation-tuned neurons in human visual cortex, our results show the importance of considering timing parameters in fMRI adaptation experiments...
  80. ncbi Improved peak detection in mass spectrum by incorporating continuous wavelet transform-based pattern matching
    Pan Du
    Robert H Lurie Comprehensive Cancer Center, Northwestern University Chicago, IL 60611, USA
    Bioinformatics 22:2059-65. 2006
    ..This approach is very sensitive to the amount of smoothing and aggressiveness of the baseline correction, which contribute to making peak detection results inconsistent between runs, instrumentation and analysis methods...
  81. ncbi Hemispheric asymmetry of auditory evoked fields elicited by spectral versus temporal stimulus change
    Hidehiko Okamoto
    Institute for Biomagnetism and Biosignalanalysis, University of Muenster, Muenster, Germany
    Cereb Cortex 19:2290-7. 2009
    ..These original findings support the hypothesis that spectral change is dominantly processed in the right hemisphere, whereas temporal change is dominantly processed in the left...
  82. ncbi Relations between digital thermal monitoring of vascular function, the Framingham risk score, and coronary artery calcium score
    Naser Ahmadi
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 West Carson Street, RB2, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 2:382-8. 2008
    ..Digital thermal monitoring (DTM) of vascular function was shown to correlate with the presence of known coronary artery disease (CAD)...
  83. ncbi Neuronal population oscillations of rat hippocampus during epileptic seizures
    Xiaoli Li
    Institute of Electrical Engineering, Yanshan University, 066004, China
    Neural Netw 21:1105-11. 2008
    ..These findings demonstrate that this method is very helpful to decompose neuronal population for understanding the underlying mechanism of epileptic seizures...
  84. ncbi A least mean-square filter for the estimation of the cardiopulmonary resuscitation artifact based on the frequency of the compressions
    Unai Irusta
    Department of Electronics and Telecommunications Engineering, University of Basque Country, Bilbao 48013, Spain
    IEEE Trans Biomed Eng 56:1052-62. 2009
    ..Our results show that the CPR artifact can be accurately modeled using only the frequency of the compressions. These can be easily registered after small changes in the hardware of the CPR compression pads...
  85. ncbi Cardiac repolarization analysis using the surface electrocardiogram
    Esther Pueyo
    Communications Technology Group, Aragon Institute for Engineering Research I3A, University of Zaragoza, 50018 Zaragoza, Spain
    Philos Trans A Math Phys Eng Sci 367:213-33. 2009
    ..Techniques that evaluate temporal dispersion of repolarization include the analysis of QT interval adaptation to heart rate changes, QT interval and T-wave variability, and T-wave alternans...
  86. ncbi A comparative study of pattern synchronization detection between neural signals using different cross-entropy measures
    Hong Bo Xie
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, People s Republic of China
    Biol Cybern 102:123-35. 2010
    ....
  87. ncbi Critical comparison of 31 commercially available digital slide systems in pathology
    Marcial Garcia Rojo
    Pathology Department, Hospital General de Ciudad Real, Spain
    Int J Surg Pathol 14:285-305. 2006
    ..The efficient use of digital microscopy by means of image analysis systems can offer important benefits to pathology departments...
  88. ncbi Exploratory data analysis of evoked response single trials based on minimal spanning tree
    N A Laskaris
    Laboratory for Human Brain Dynamics, Brain Science Institute, RIKEN, Wako-shi 351-01, Japan
    Clin Neurophysiol 112:698-712. 2001
    ....
  89. ncbi Ipsilateral area 3b responses to median nerve somatosensory stimulation
    Akitake Kanno
    Ryogo Center, Kohnan Hospital, 4 20 1 Nagamachi minami, Taihaku ku, Sendai, Japan
    Neuroimage 18:169-77. 2003
    ..Therefore, the somatosensory afferent pathway from the hand may reach directly to the ipsilateral area 3b at least in part of the human population...
  90. ncbi On the use of wavelet denoising and spike sorting techniques to process electroneurographic signals recorded using intraneural electrodes
    Luca Citi
    ARTS and CRIM Labs, Scuola Superiore Sant Anna, Pisa, Italy
    J Neurosci Methods 172:294-302. 2008
    ..This strategy could allow the development of more effective closed-loop neuroprostheses and hybrid bionic systems connecting the human nervous system with artificial devices...
  91. ncbi Tissue characterization with an electrical spectroscopy SVM classifier
    Shlomi Laufer
    Research Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    IEEE Trans Biomed Eng 56:525-8. 2009
    ..The results demonstrate the feasibility of the concept and illustrate the tissue characterization ability of this classifier...
  92. ncbi Breathing cardiovascular variability and baroreflex in mechanically ventilated patients
    Andry Van de Louw
    Unité de Biologie Intégrative des Adaptations à l Exercise INSERM 902 EA 3872, Genopole, ZAC du Bras de Fer, Evry, France
    Am J Physiol Regul Integr Comp Physiol 295:R1934-40. 2008
    ..Positive pressure ventilation exerts mainly a mechanical effect on SBP, whereas its influence on HR variability seems more complex, suggesting a role for neural influences...
  93. ncbi Respiratory cycle as time basis: an improved method for averaging olfactory neural events
    Stéphane G Roux
    Laboratoire de Physique, Ecole Normale Superieure de Lyon, 46 allee d Italie, 69364 Lyon Cedex 07, France
    J Neurosci Methods 152:173-8. 2006
    ....
  94. ncbi Orientation-specific adaptation in human visual cortex
    Geoffrey M Boynton
    The Salk Institute, La Jolla, California 92037 1099, USA
    J Neurosci 23:8781-7. 2003
    ....
  95. ncbi Randomization tests for ERP topographies and whole spatiotemporal data matrices
    Eric Maris
    Nijmegen Institute of Cognition and Information, University of Nijmegen, 6500 HE Nijmegen, The Netherlands
    Psychophysiology 41:142-51. 2004
    ..New randomization tests are presented and applied to two data sets, one coming from a psychopharmacological experiment and the other from an ERP experiment in visual word recognition...
  96. ncbi Detection of very low-frequency oscillations of cerebral haemodynamics is influenced by data detrending
    T Muller
    Centre for Data Analysis and Modelling, University of Freiburg, Freiburg, Germany
    Med Biol Eng Comput 41:69-74. 2003
    ..021 +/- 0.007 Hz, mean +/- SD), confirming earlier findings based on visual inspection of data...
  97. ncbi Gamma-band activity dissociates between matching and nonmatching stimulus pairs in an auditory delayed matching-to-sample task
    Susanne Leiberg
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, MEG Center, Otfried Müller Str 47, 72076 Tubingen, Germany
    Neuroimage 30:1357-64. 2006
    ..When S1 and S2 were identical, no further representation was required. In contrast, for nonmatching pairs, a second representation was activated over right parietal areas...
  98. ncbi Motion processing in the macaque: revisited with functional magnetic resonance imaging
    A S Tolias
    Max Planck Institute for Biological Cybernetics, Tuebingen, 72076 Germany
    J Neurosci 21:8594-601. 2001
    ....
  99. ncbi Comparison of time-frequency analysis techniques in intraoperative somatosensory evoked potential (SEP) monitoring
    Yong Hu
    Department of Orthopaedic Surgery, The University of Hong Kong, Duchess of Kent Children s Hospital, 12 Sandy Bay Road, Hong Kong
    Comput Biol Med 32:13-23. 2002
    ..The most appropriate TFA technique may depend on the type of SEP signal, Short term Fourier transform (STFT) with a 20 point length Hanning window probably provides the best result for SEP signals...
  100. ncbi Machine learning for real-time single-trial EEG-analysis: from brain-computer interfacing to mental state monitoring
    Klaus Robert Muller
    Technical University Berlin, Str des 17 Juni 135, 10623 Berlin, Germany
    J Neurosci Methods 167:82-90. 2008
    ..Also, spelling with the novel BBCI-based Hex-o-Spell text entry system, which gains communication speeds of 6-8 letters per minute, is discussed. Finally the results of a real-time arousal monitoring experiment are presented...
  101. ncbi Epileptic transitions: model predictions and experimental validation
    Piotr Suffczynski
    Laboratory of Biomedical Physics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
    J Clin Neurophysiol 22:288-99. 2005
    ..Predictions of bistable computational model with experimental results from different types of epilepsy are compared...

Research Grants69

  1. Hemodynamic and Cognitive Function in Cardiovascular Disease
    Lawrence H Sweet; Fiscal Year: 2011
    ..Findings are expected to provide data and methods that will increase the clinical utility of FMRI for the assessment of CVD patients, and a better understanding of the mechanisms causing cognitive impairment. ..
  2. Decoupling Dynamics of the Autonomic Nervous System
    Ki Chon; Fiscal Year: 2005
    ..abstract_text> ..
  3. Very-High-Frequency Ultrasound Imaging With Coded Signals and Annular Arrays
    Jonathan Mamou; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  4. Phase resetting using DC stimulation for seizure blockage
    Ivan Osorio; Fiscal Year: 2007
    ..3B. The significant advances made in the control of fatal arrhythmias are in part attributable to the use by cardiologists of phase resetting as an investigative and therapeutic tool. [unreadable] [unreadable] [unreadable]..
  5. Third International Workshop on Seizure Prediction - Freiburg, Germany, 2007
    Hitten Zaveri; Fiscal Year: 2007
    ..Investigators whose participation will be supported will be invited speakers and junior and senior investigators including women and racial and ethnic minorities. [unreadable] [unreadable] [unreadable]..
  6. Automated Test of Word Recognition - Phase II
    Robert Margolis; Fiscal Year: 2006
    ..A pilot study will test the method on a Spanish-language speech-recognition test. [unreadable] [unreadable]..
  7. Decoupling of Principal Renal Autoregulatory Mechanisms
    Ki Chon; Fiscal Year: 2005
    ..By exercising this model, as described under Specific Aim (5), we plan to begin understanding the underlying reasons for the changes observed in autoregulation under pathological conditions. ..
  8. Development of Improved Earphone for Hearing Testing
    Robert Margolis; Fiscal Year: 2008
    ..In this project an earphone is being developed that can be used in both automated and manual testing and will significantly increase the efficiency, accuracy, and accessibility. [unreadable] [unreadable] [unreadable]..
  9. Inferring Cortical Feed-Forward and Feedback Processes with Human Neuroimaging
    SEPPO AHLFORS; Fiscal Year: 2009
    ..It could lead to a better understanding of the neural mechanisms underlying cognitive functions, as well as to potential applications for revealing mechanisms of neural disorders. ..
  10. Developing Predictive Methods for Sudden Cardiac Death
    Ki Chon; Fiscal Year: 2002
    ..It is intended that the algorithm will be applicable to other physiological systems and may become a widely accepted noninvasive clinical alternative. ..
  11. Individual Differences in Extrastriatal DA Release
    David Zald; Fiscal Year: 2009
    ..abstract_text> ..
  12. Measurement of Absolute Cerebral Blood Volume using Magnetic Resonance Imaging
    Hanzhang Lu; Fiscal Year: 2008
    ..In this project, a new technique will be developed to measure CBV in human brain using MRI. [unreadable] [unreadable] [unreadable]..
  13. OPTICAL DETECTION OF INTRAVENOUS INFILTRATION
    LEONARD WINCHESTER; Fiscal Year: 2008
    ..Specific aims of the Competing Continuation effort are: to refine the IV infiltration detection device, to conduct a clinical trial, and to submit a 510 (k) application to the U.S. Food and Drug Administration. ..
  14. MECHANICS OF ACUTE LUNG INJURY
    Jason Bates; Fiscal Year: 2009
    ..The results of our studies are expected to lead to the design of physiologically-based lung recruitment strategies that can be tailored to the individual patient with ALI. This will set the stage for future clinical trials. ..
  15. A Computational Approach for 3D Brain Source Imaging
    Bin He; Fiscal Year: 2010
    ..The availability of a noninvasive imaging technology to identify and image the epileptogenic foci would benefit numerous patients suffering from epilepsy and the healthcare system. ..
  16. Noninvasive Methemoglobin Monitoring Technology
    LEONARD WINCHESTER; Fiscal Year: 2007
    ..A noninvasive and reliable methemoglobin sensor will have great impact on therapeutic decision time. [unreadable] [unreadable] [unreadable]..
  17. Three Dimensional Electrocardiographic Imaging
    Bin He; Fiscal Year: 2010
    ....
  18. Structural-functional MRI Studies of Memory in MCI & AD
    Bradford Dickerson; Fiscal Year: 2007
    ..abstract_text> ..
  19. Low power analog electronics for an implantable cortical prosthetic
    Rahul Sarpeshkar; Fiscal Year: 2010
    ..It will also enable portable large-scale long-term instrumentation and monitoring of the brain in experimental neuroscience in a wireless fashion. ..
  20. Randomized Trial of Tinnitus Retraining Therapy
    Richard Tyler; Fiscal Year: 2008
    ..If TRT is shown to be no more effective than masking or counseling, professionals should focus on more efficient therapeutic techniques. This experiment will test the neurophysiological model of tinnitus. [unreadable] [unreadable]..
  21. Electrocorticographic Study of Categorical Phoneme Perception in the Human Tempor
    Edward Chang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  22. In-vivo intravascular autoradiography with storage phosphor detector
    POLAD SHIKHALIEV; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  23. MULTI-MODAL INTERACTIONS IN SPATIAL AND TEMPORAL PERCEPTION
    Gregg Recanzone; Fiscal Year: 2009
    ..These insights will provide a cornerstone for understanding complex perceptions and cognitive ability. ..
  24. Ultrasound-Enhanced Delivery of Medications to the Eye
    Ronald Silverman; Fiscal Year: 2008
    ..We will visualize the distribution of the molecules within the sclera, choroid and retina to evaluate transport and characterize any tissue damage that might have occurred microscopically and by apoptosis assays. ..
  25. Hot Flashes and Anxiety Sensitivity Among Breast Cancer Survivors
    Laura Hanisch; Fiscal Year: 2008
    ..The goal is to develop better strategies for the self-management of hot flashes using cognitive-behavioral techniques. [unreadable] [unreadable] [unreadable]..
  26. Three-Class ROC Analysis for Task-Based Medical Image Quality Assessment
    Xin He; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  27. Center for Pediatric Stem/Progenitor Cell Translational Research
    Alice Tarantal; Fiscal Year: 2008
    ..If imaging techniques can be developed that allows one to monitor the cells over time, this would provide a very powerful tool to determine the fate of the cells after injection into humans. ..
  28. Non-invasive Fast Optical Imaging of Visual and Motor Processing
    Andrei Medvedev; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  29. Assessment of Lung function in Mice
    Jason Bates; Fiscal Year: 2009
    ....
  30. Function of Vestibular-Nerve Afferent Types
    Timothy Hullar; Fiscal Year: 2008
    ..Findings from this study will allow better understanding of pathologies of the peripheral vestibular system. ..
  31. Reduction and Telemetry of Neural Data for an Implantable Data Acquisition System
    MICHAEL RIZK; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  32. Time course of learning perceptual pop-out in V1 and V2
    Matthew Smith; Fiscal Year: 2006
    ..In addition, knowledge of the limits of visual cortical plasticity are important in understanding diseases such as amblyopia, in which there are known changes in the cortex as a result of a visual impairment. ..
  33. Multiple Memory Systems in Action Selection
    JOSHUA BERKE; Fiscal Year: 2005
    ..abstract_text> ..
  34. FMRI Investigations of Anterior Temporal Lobe Function
    Colin Humphries; Fiscal Year: 2006
    ..Finally, the third experiment will investigate the influence of prosody on ATSA activation. We predict that disrupting sentence prosody will affect activation levels in the ATSA. ..
  35. Modeling and Assessment of Cerebrovascular Autoregulation
    Michael Daley; Fiscal Year: 2006
    ..Simulation of ICP with a third order windkessel model of intracranial pressure dynamics will be used to examine the biomechanical mechanisms underlying active and passive regulation of cerebral blood flow. [unreadable] [unreadable]..
  36. Optical Imaging of Retinal Blood Circulation
    LEONARD WINCHESTER; Fiscal Year: 2005
    ..A noninvasive, realtime retinal imager allows the physicians to record and keep track of patients' retinal hemodynamics to detect early signs of ocular disorders. ..
  37. ALCOHOL MODULATION OF CARDIAC CALCIUM CHANNELS
    Gary Aistrup; Fiscal Year: 2003
    ..This novel action may have major implications, given the widespread clinical use of dihydropyridines and other calcium channel antagonists. Drug interactions of this type will be an important focus of the project. ..
  38. Neurocognitive Outcome of Infants of Diabetic Mothers
    Charles Nelson; Fiscal Year: 2009
    ..Given that approximately 10% of all pregnancies are complicated by maternal diabetes, the current project has important implications for public health. ..
  39. VERY-HIGH-FREQUENCY ULTRASOUND ARRAYS FOR OPHTHALMOLOGY
    Jeffrey Ketterling; Fiscal Year: 2005
    ..Concepts are validated and refined using scans of in-vitro porcine eyes and in-vivo rabbit eyes. ..
  40. Phonetic and prosodic effects in perceptual assimilation
    JAMES HARNSBERGER; Fiscal Year: 2005
    ....
  41. UWMC POSITRON EMISSION IMAGING ANIMAL FACILITY
    Thomas Lewellen; Fiscal Year: 2005
    ..Animal support and radiopharmaceuticals will be provided by existing cost centers within the University of Washington Department of Radiology. ..
  42. Effects of High-Rate Pulse Trains on Discrimination
    Christina Runge Samuelson; Fiscal Year: 2006
    ..The data analyses will focus on comparisons between discrimination ability, with and without high-rate pulse trains. ..
  43. COGNITIVE EVENT-RELATED POTENTIALS AND BRAIN MATURATION
    Patricia Davies; Fiscal Year: 2002
    ..The PI will prepare manuscripts for peer reviewed journals reporting the results of these studies and supervise graduate students in related research projects. ..
  44. HIGH RESOLUTION PET DETECTORS FOR ONCOLOGY APPLICATIONS
    Thomas Lewellen; Fiscal Year: 2002
    ..g. mouse, rat, rabbit, dog, and primate). The final detector module designs will be fully documented (including ASIC fabrication files) to allow duplication at other laboratories. ..
  45. Flow Visualization in the Canine Larynx During Phonation
    Siddarth Khosla; Fiscal Year: 2006
    ..Training in recognizing clinical applications of the work will be fostered by consultations with two prominent laryngologists, Dr. Gerald Berke and Dr. Randal Paniello. ..
  46. ROLES OF NEUROTROPHINS IN OCULAR DOMINANCE PLASTICITY
    Takuji Kasamatsu; Fiscal Year: 2002
    ..Using the "in vivo dilution curve" thus obtained, we will titrate the lowest-yet-effective concentrations of BDNF for its physiological effects. ..
  47. Raman Determination of Ligament Tension
    LEONARD WINCHESTER; Fiscal Year: 2006
    ..Measurements of MCL and ACL ligaments as functions of applied stress will be used to demonstrate the feasibility of the proposed technique. [unreadable] [unreadable] [unreadable] [unreadable]..
  48. New Wavelet-based and Source Separation Methods for fMRI
    INGRID DAUBECHIES; Fiscal Year: 2006
    ..By using sparsity together with time-frequency methods, we will develop new source separation algorithms and will demonstrate their robustness on both simulated and real data. ..
  49. PERINATAL ASSESSMENT OF AT RISK POPULATIONS
    WILLIAM FIFER; Fiscal Year: 2005
    ....
  50. Mesenchymal Stem Cells for Fetal Gene Delivery
    Alice Tarantal; Fiscal Year: 2006
    ..abstract_text> ..
  51. The Pathophysiology of T-wave Alternans
    Sanjiv Narayan; Fiscal Year: 2005
    ..This structured approach will ensure the successful completion of this project and, in this way, the development of the applicant into an independent clinician-investigator. ..
  52. Age related effects on macaque auditory cortex
    Gregg Recanzone; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  53. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2003
    ..The position of the investigators is that this study will provide definitive evidence that the TDH is incorrect and that a more complex model of the functional neuroanatomy of syntactic processing is needed. ..
  54. fMRI studies of semantic and episodic memory retrieval
    Lee Ryan; Fiscal Year: 2007
    ..The study will not only directly test some of the assertions from MTT, but it will also provide important information regarding the neural mechanisms underlying long-term storage and retrieval in humans. [unreadable] [unreadable]..
  55. Human Epileptic Foci: Hidden Cortical Relationships
    Vernon Towle; Fiscal Year: 2004
    ..abstract_text> ..
  56. Improved MRI techniques for measurement of absolute temperature distributions
    NICHOLAS TODD; Fiscal Year: 2008
    ..A temporally constrained reconstruction algorithm has been shown to be capable of reducing scan time and can also be implemented with any pulse sequence. [unreadable] [unreadable] [unreadable]..
  57. Channel Interaction in Cochlear Implant Subjects
    JULIE BIERER; Fiscal Year: 2004
    ..The results of these studies could influence the development of future cochlear implant electrodes and speech processing strategies, ideally, leading to improved performance for most cochlear implant subjects. ..
  58. Interest of IKr-related Abnormalities of ECGs to Improve Drug-safety Evaluation
    Jean Philippe Couderc; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  59. Network mechanisms for respiratory rhythm generation
    Nicholas Mellen; Fiscal Year: 2008
    ..We propose to test this hypothesis at the network level, by selectively modulating VIEB and VDEB networks, and at the single neuron level, by characterizing perturbation responses in synaptically isolated VIEBs and VDEBs. ..
  60. Reducing the Disproportionate Burden of Orofacial Injury
    Vivek Shetty; Fiscal Year: 2007
    ..abstract_text> ..
  61. VOLUMETRIC PROTON MR SPECTROSCOPIC IMAGING
    ANDREW MAUDSLEY; Fiscal Year: 2001
    ..As techniques are developed, they will support ongoing clinical studies investigating changes of brain metabolites associated with Alzheimer's disease and aging, epilepsy, substance abuse, and schizophrenia. ..
  62. Data Processing for Clinical MR Spectroscopy and Imaging
    ANDREW MAUDSLEY; Fiscal Year: 2006
    ..Grant support will be directed towards providing awards for student- and postdoctoral- level attendees to attend the meeting. [unreadable] [unreadable]..
  63. Optimizing Hearing Aid Fitting for Older Adults
    Robyn Cox; Fiscal Year: 2007
    ..For these individuals, resources presently allocated to hearing aid purchase would be used more effectively for alternate rehabilitation methods. Outcomes of 100 bilateral hearing aid fittings will be evaluated. [unreadable] [unreadable]..
  64. PROTON MR SPECTROSCOPIC IMAGING OF EPILEPSY
    ANDREW MAUDSLEY; Fiscal Year: 2005
    ..The improved metabolite image reconstruction and regional pH measurement techniques also have potential clinical applications in other areas, such as cancer, stroke, and brain trauma. ..
  65. DATA PROCESSING FOR MR SPECTROSCOPIC IMAGING
    ANDREW MAUDSLEY; Fiscal Year: 2001
    ..This development will support ongoing clinical studies investigating changes of brain metabolites associated with Alzheimer's disease and aging, epilepsy, and multiple sclerosis. ..
  66. DATA PROCESSING FOR MR SPECTROSCOPIC IMAGING
    ANDREW MAUDSLEY; Fiscal Year: 2003
    ..This development will support ongoing clinical studies investigating changes of brain metabolites associated with Alzheimer's disease and aging, epilepsy, and multiple sclerosis. ..
  67. VOLUMETRIC MR MOLECULAR IMAGING OF BRAIN
    ANDREW MAUDSLEY; Fiscal Year: 2006
    ..Matson). This development will establish the range and variance of normal metabolite profiles and provide valuable comparative data for numerous clinical investigations that use short-TE 1H MRS. [unreadable] [unreadable]..