Genomes and Genes
Summary: A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.
Publications262 found, 100 shown here
- MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammalsJohn Tsang
Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Mol Cell 26:753-67. 2007..Our results strongly suggest that coordinated transcriptional and miRNA-mediated regulation is a recurrent motif to enhance the robustness of gene regulation in mammalian genomes...
- Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alphaI Novoa
Skirball Institute of Biomolecular Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
J Cell Biol 153:1011-22. 2001..These findings implicate GADD34-mediated dephosphorylation of eIF2alpha in a negative feedback loop that inhibits stress-induced gene expression, and that might promote recovery from translational inhibition ..
- The p53 pathway: positive and negative feedback loopsSandra L Harris
The Cancer Institute of New Jersey and the Institute for Advanced Study, New Jersey, NJ, USA
Oncogene 24:2899-908. 2005..number of other signal transduction pathways in the cell and a number of positive and negative autoregulatory feedback loops act upon the p53 response...
- A chemokine-driven positive feedback loop organizes lymphoid folliclesK M Ansel
Department of Microbiology and Immunology, University of California San Francisco, 94143, USA
Nature 406:309-14. 2000..a cytokine that promotes follicular dendritic cell development and BLC expression, establishing a positive feedback loop that is likely to be important in follicle development and homeostasis...
- Optimal feedback control as a theory of motor coordinationEmanuel Todorov
Department of Cognitive Science, University of California, San Diego, 9500 Gilman Dr, La Jolla, California 92093 0515, USA
Nat Neurosci 5:1226-35. 2002..Here we propose an alternative theory based on stochastic optimal feedback control...
- The decision to enter mitosis: feedback and redundancy in the mitotic entry networkArne Lindqvist
Department of Medical Oncology, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands
J Cell Biol 185:193-202. 2009..Within this network, several positive feedback loops can amplify cyclin B-Cdk1 activation to ensure complete commitment to a mitotic state once the decision to ..
- Computational principles of movement neuroscienceD M Wolpert
Sobell Department of Neurophysiology, Institute of Neurology, University College London, UK
Nat Neurosci 3:1212-7. 2000..Our goal is to demonstrate how specific models emerging from the computational approach provide a theoretical framework for movement neuroscience...
- Optimality principles in sensorimotor controlEmanuel Todorov
Department of Cognitive Science, University of California San Diego, La Jolla, California 92093 0515, USA
Nat Neurosci 7:907-15. 2004..Traditional emphasis has been on optimizing desired movement trajectories while ignoring sensory feedback. Recent work has redefined optimality in terms of feedback control laws, and focused on the mechanisms that ..
- Bayesian integration in sensorimotor learningKonrad P Kording
Sobell Department of Motor Neuroscience, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
Nature 427:244-7. 2004..results from combining information about the distribution of velocities-the prior-with evidence from sensory feedback. As uncertainty increases, when playing in fog or at dusk, the system should increasingly rely on prior knowledge...
- Delay in feedback repression by cryptochrome 1 is required for circadian clock functionMaki Ukai-Tadenuma
Laboratory for Systems Biology, RIKEN Center for Developmental Biology, Chuo Ku, Kobe, Hyogo, Japan
Cell 144:268-81. 2011Direct evidence for the requirement of delay in feedback repression in the mammalian circadian clock has been elusive...
- Preventing smoking relapse via Web-based computer-tailored feedback: a randomized controlled trialIman Elfeddali
Department of Health Promotion, School for Public Health and Primary Care CAPHRI, Maastricht University, Maastricht, Netherlands
J Med Internet Res 14:e109. 2012..The Stay Quit for You (SQ4U) study compared two Web-based computer-tailored smoking relapse prevention programs with different types of planning strategies versus a control group...
- ERP correlates of feedback and reward processing in the presence and absence of response choiceNick Yeung
Department of Psychology, Princeton University, Princeton, NJ 08544, USA
Cereb Cortex 15:535-44. 2005The feedback negativity is a component of the event-related brain potential that is elicited by feedback stimuli associated with unfavorable outcomes...
- Engineering stability in gene networks by autoregulationA Becskei
EMBL, Structures and Biocomputing, Heidelberg, Germany
Nature 405:590-3. 2000..It has been proposed, but not demonstrated, that autoregulatory, negative feedback loops in gene circuits provide stability, thereby limiting the range over which the concentrations of network ..
- Using theory to synthesise evidence from behaviour change interventions: the example of audit and feedbackBenjamin Gardner
Centre for Outcomes Research and Effectiveness, University College London, 1 19 Torrington Place, London WC1E 7HB, UK
Soc Sci Med 70:1618-25. 2010..We illustrate this method with an analysis of 'audit and feedback' interventions, based on data from a Cochrane review...
- Feedback control of regulatory T cell homeostasis by dendritic cells in vivoGuillaume Darrasse-Jèze
Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
J Exp Med 206:1853-62. 2009..We demonstrate the existence of a feedback regulatory loop between DCs and T reg cells...
- Dependence of stem cell fate in Arabidopsis on a feedback loop regulated by CLV3 activityU Brand
Institut fur Entwicklungsbiologie, Universitat zu Koln, Gyrhofstrabetae 17, D 50923 Köln, Germany
Science 289:617-9. 2000..fate of stem cells in plant meristems is governed by directional signaling systems that are regulated by negative feedback. In Arabidopsis thaliana, the CLAVATA (CLV) genes encode the essential components of a negative, stem cell-..
- puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in DrosophilaE Martin-Blanco
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK
Genes Dev 12:557-70. 1998..a consequence of the activity of the JNK pathway and that during dorsal closure, JNK signaling has a dual role: to activate an effector, encoded by decapentaplegic, and an element of negative feedback regulation encoded by puckered.
- Impact of workplace based assessment on doctors' education and performance: a systematic reviewAlice Miller
Peninsula College of Medicine and Dentistry, University of Plymouth, Plymouth PL4 8AA, UK
BMJ 341:c5064. 2010..To investigate the literature for evidence that workplace based assessment affects doctors' education and performance...
- Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulationC Meno
Division of Molecular Biology, Osaka University, Japan
Mol Cell 4:287-98. 1999..Expression of antivin is dependent on Nodal signaling, revealing a feedback loop wherein Nodal signals induce their antagonists Lefty2 and Antivin to restrict Nodal signaling during ..
- Chronic stress promotes palatable feeding, which reduces signs of stress: feedforward and feedback effects of chronic stressNorman Pecoraro
Department of Physiology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143 0444
Endocrinology 145:3754-62. 2004..The results of this experiment tend to support our model of chronic effects of stress and GCs, showing a stressor-induced preference for comfort food, and a comfort-food reduction in activity of the HPA axis...
- Systematic review of the literature on assessment, feedback and physicians' clinical performance: BEME Guide No. 7Jon Veloski
Center for Research in Medical Education and Health Care, Jefferson Medical College, Thomas Jefferson University, Philadelphia 19107, USA
Med Teach 28:117-28. 2006There is a basis for the assumption that feedback can be used to enhance physicians' performance. Nevertheless, the findings of empirical studies of the impact of feedback on clinical performance have been equivocal.
- Meta-analysis: audit and feedback features impact effectiveness on care qualitySylvia J Hysong
Houston VA HSR and D Center of Excellence, Health Services Research and Development Service, Department of Veterans Affairs Medical Center, TX, USA
Med Care 47:356-63. 2009Audit and feedback (A&F) has long been used to improve quality of care, albeit with variable results...
- The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2F J Stott
Imperial Cancer Research Fund Laboratories, P O Box 123, 44 Lincoln s Inn Fields, London WC2A 3PX, UK
EMBO J 17:5001-14. 1998..However, p14(ARF) expression is not involved in the response to DNA damage. These results place p14(ARF) in an independent pathway upstream of p53 and imply that CDKN2A encodes two proteins that are involved in tumour suppression...
- Sensory prediction errors drive cerebellum-dependent adaptation of reachingYa weng Tseng
Dept of Neurology, The Johns Hopkins School of Medicine, Kennedy Krieger Institute, Baltimore, MD 21205, USA
J Neurophysiol 98:54-62. 2007..Therefore adaptation to visuomotor perturbations depends on the cerebellum and is driven by the mismatch between predicted and actual sensory outcome of motor commands...
- Feedback regulation in multistage cell lineagesWing Cheong Lo
Departments of Mathematics, University of California, Irvine, CA, United States
Math Biosci Eng 6:59-82. 2009..self-renewal and differentiation of stem and progenitor cells within such lineages have been shown to be under feedback regulation...
- Internet-based brief personalized feedback intervention in a non-treatment-seeking population of adult heavy drinkers: a randomized controlled trialAnders Blædel Gottlieb Hansen
National Institute of Public Health, Faculty of Health Sciences, University of Southern Denmark, Copenhagen, Denmark
J Med Internet Res 14:e98. 2012..Internet-based interventions for heavy drinkers show promising results, but existing research is characterized by few studies in nonstudent adult populations and few comparisons with appropriate control groups...
- MiR-34, SIRT1 and p53: the feedback loopMunekazu Yamakuchi
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cell Cycle 8:712-5. 2009..Based on this observation, we propose a positive feedback loop, in which p53 induces expression of miR-34a which suppresses SIRT1, increasing p53 activity.
- A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosisFangwei Wang
Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Curr Biol 21:1061-9. 2011..We propose that Aurora B activity triggers a CPC-Haspin-H3T3ph feedback loop that promotes generation of H3T3ph on chromatin...
- Spatio-temporal prediction modulates the perception of self-produced stimuliS J Blakemore
Wellcome Department of Cognitive Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
J Cogn Neurosci 11:551-9. 1999..e., its tickliness) is proportional to the error between the sensory feedback predicted by an internal forward model of the motor system and the actual sensory feedback produced by the ..
- How emotion shapes behavior: feedback, anticipation, and reflection, rather than direct causationRoy F Baumeister
Florida State University, Florida, USA
Pers Soc Psychol Rev 11:167-203. 2007..Instead, the authors develop a theory of emotion as a feedback system whose influence on behavior is typically indirect...
- The impact of feedback semantics in visual word recognition: number-of-features effects in lexical decision and naming tasksPenny M Pexman
Department of Psychology, University of Calgary, Alberta, Canada
Psychon Bull Rev 9:542-9. 2002The notion of feedback activation from semantics to both orthography and phonology has recently been used to explain a number of semantic effects in visual word recognition, including polysemy effects (Hino & Lupker, 1996; Pexman &..
- Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1Pin Wang
National Key Laboratory of Medical Immunology, Institute of Immunology, Second Military Medical University, Shanghai, China
J Immunol 185:6226-33. 2010..And the inducible miR-155 feedback promotes type I IFN signaling, thus suppressing viral replication...
- Contribution of feedforward, lateral and feedback connections to the classical receptive field center and extra-classical receptive field surround of primate V1 neuronsAlessandra Angelucci
Department of Ophthalmology and Visual Science, Moran Eye Center, University of Utah, 50 North Medical Drive, Salt Lake City, UT 84132, USA
Prog Brain Res 154:93-120. 2006..Geniculocortical feedforward (FF), V1 lateral and extrastriate feedback (FB) connections to V1 could all contribute to generating the RF center and surround of V1 neurons...
- MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammationMagdalena M Gorska
Division of Allergy and Immunology, Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
J Exp Med 204:1637-52. 2007..This pattern of activation is essential for many NF-kappaB-regulated genes and development of inflammation. Thus, the MK2-HSP27 pathway is an excellent target for therapeutic control of localized inflammatory diseases...
- Written online situational feedback via mobile phone to support self-management of chronic widespread pain: a usability study of a Web-based interventionÓlöf Birna Kristjánsdóttir
Faculty of Nursing, Oslo University College, Oslo, Norway
BMC Musculoskelet Disord 12:51. 2011..This pretrial study aimed to develop and test the usability of a four-week Internet intervention delivered by a Web-enabled mobile phone to support self-management of chronic widespread pain...
- The coordination of movement: optimal feedback control and beyondJorn Diedrichsen
Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queens Square, London, UK
Trends Cogn Sci 14:31-9. 2010Optimal control theory and its more recent extension, optimal feedback control theory, provide valuable insights into the flexible and task-dependent control of movements...
- Redundant pathways for negative feedback regulation of bile acid productionLi Wang
Department of Molecular and Cellular Biology, Houston, TX 77030, USA
Dev Cell 2:721-31. 2002The orphan nuclear hormone receptor SHP has been proposed to have a key role in the negative feedback regulation of bile acid production...
- Brief intervention for heavy-drinking college students: 4-year follow-up and natural historyJ S Baer
Center of Excellence in Substance Abuse Treatment and Education, VA Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
Am J Public Health 91:1310-6. 2001..This study examined long-term response to an individual preventive intervention for high-risk college drinkers relative to the natural history of college drinking...
- Feedback and reward processing in high-functioning autismMichael J Larson
Department of Psychology, Brigham Young University, Provo, UT 84602, USA
Psychiatry Res 187:198-203. 2011..Such deficits may be influenced by poor ability to process feedback and rewards...
- Control of Dpp morphogen signalling by a secreted feedback regulatorRobin Vuilleumier
Institute for Biology I, Albert Ludwigs University of Freiburg, Hauptstrasse 1, D 79104 Freiburg, Germany
Nat Cell Biol 12:611-7. 2010..We show that Pent interacts with the glypican Dally to control Dpp distribution and provide evidence that proper establishment of the BMP morphogen gradient requires the inbuilt feedback loop embodied by Pent.
- Competition between feedback loops underlies normal and pathological dynamics in the basal gangliaArthur Leblois
Laboratoire de Neurophysique et Physiologie du Système Moteur, Centre National de la Recherche Scientifique, Unite Mixte de Recherche 8119, Universite Rene Descartes, 75270 Paris, France
J Neurosci 26:3567-83. 2006..the subthalamic nucleus, the internal pallidum (GPi), the thalamus, and the cortex are involved in closed feedback loops...
- A positive feedback loop coordinates growth and patterning in the vertebrate limbL Niswander
Department of Anatomy, School of Medicine, University of California at San Francisco 94143 0452
Nature 371:609-12. 1994..Moreover, Shh expression in mesenchyme can be activated by FGF4 in combination with retinoic acid. Once induced, Shh expression can be maintained by FGF4 alone, thus establishing a positive feedback loop between ZPA and ridge.
- Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levelsP E Hardin
Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02254
Nature 343:536-40. 1990..The observations indicate that the cycling of per-encoded protein could result from per RNA cycling, and that there is a feedback loop through which the activity of per-encoded protein causes cycling of its own RNA.
- IFN induces miR-21 through a signal transducer and activator of transcription 3-dependent pathway as a suppressive negative feedback on IFN-induced apoptosisChuan He Yang
Departments of Pathology and Laboratory Medicine and Physiology and Center for Integrative Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Cancer Res 70:8108-16. 2010..Our results identify miR-21 as a novel IFN target gene that functions as a key feedback regulator of IFN-induced apoptosis.
- Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stressYanjun Ma
Department of Genetics and Tumor Cell Biology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Biol Chem 278:34864-73. 2003..Our study delineates a negative feedback regulatory loop in which the eIF-2 alpha-controlled inhibition of protein translation leads to GADD34 induction, ..
- Long-distance feedback projections to area V1: implications for multisensory integration, spatial awareness, and visual consciousnessSimon Clavagnier
INSERM U371, IFR19 corrected Université Claude Bernard Lyon 1, Bron, France
Cogn Affect Behav Neurosci 4:117-26. 2004..We have, therefore, reexamined feedback projections to area V1, using retrograde tracer injections in this area In addition to well-known areas, ..
- Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitroEdward O Mann
University Laboratory of Physiology, Oxford University, Parks Road, Oxford OX1 3PT, UK
Neuron 45:105-17. 2005..AMPA receptor-mediated recurrent excitation was necessary for the synchronization of interneuronal discharge, which strongly supports a synaptic feedback model for the generation of hippocampal gamma oscillations.
- PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loopVardit Lavi-Moshayoff
Minerva Center for Calcium and Bone Metabolism, Nephrology Services, Hadassah Hebrew Univ Medical Center, PO Box 12000, Jerusalem, Israel 91120
Am J Physiol Renal Physiol 299:F882-9. 2010..The effect of PTH on FGF23 completes a bone-parathyroid endocrine feedback loop. Importantly, secondary hyperparathyroidism is essential for the high-FGF23 levels in early CKD.
- Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor proteinElena Tamagno
Department of Experimental Medicine and Oncology, University of Torino, Torino, Italy
J Neurochem 104:683-95. 2008..Our findings suggest a mechanism by which OS induces BACE1 transcription, thereby promoting production of pathological levels of amyloid beta in AD...
- Feedback control of the protein kinase TAK1 by SAPK2a/p38alphaPeter C F Cheung
MRC Protein Phosphorylation Unit, School of Life Sciences, MSI WTB complex, Dow Street, University of Dundee, Dundee DD1 5EH, UK
EMBO J 22:5793-805. 2003..Our results suggest that TAB1 participates in a SAPK2a/p38alpha-mediated feedback control of TAK1, which not only limits the activation of SAPK2a/p38alpha but synchronizes its activity with other ..
- Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuitPaul S Buckmaster
Department of Comparative Medicine, Stanford University School of Medicine, Stanford, California 94305 5330, USA
J Neurosci 22:6650-8. 2002..Rather, it replaces a distally distributed and disynaptic excitatory feedback circuit with one that is local and monosynaptic.
- Effects of correct and transformed visual feedback on rhythmic visuo-motor tracking: tracking performance and visual search behaviorM Roerdink
Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, 1081BT Amsterdam, The Netherlands
Hum Mov Sci 24:379-402. 2005The effects of correct and transformed visual feedback on rhythmic unimanual visuo-motor tracking were examined, focusing on tracking performance (accuracy and stability) and visual search behavior...
- The development of computer-generated tailored interventionsA Dijkstra
Department of Clinical and Health Psychology, Leiden University, P O Box 9555, 2300 RB, Leiden, Netherlands
Patient Educ Couns 36:193-203. 1999..This methodology may result in largely different tailored interventions depending on the theoretical framework used, the adaptation of the messages and the inclusion of feedback.
- Neural mechanisms underlying auditory feedback control of speechJason A Tourville
Department of Cognitive and Neural Systems, Boston University, 677 Beacon St, Boston, MA 02215, USA
Neuroimage 39:1429-43. 2008The neural substrates underlying auditory feedback control of speech were investigated using a combination of functional magnetic resonance imaging (fMRI) and computational modeling...
- Neural correlates of verbal feedback processing: an fMRI study employing overt speechIngrid K Christoffels
Department of Cognitive Neuroscience, Faculty of Psychology, Maastricht University, The Netherlands
Hum Brain Mapp 28:868-79. 2007Speakers use external auditory feedback to monitor their own speech. Feedback distortion has been found to increase activity in the superior temporal areas...
- vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clockShawn A Cyran
Department of Biology, New York University, 100 Washington Square East, New York, NY 10003, USA
Cell 112:329-41. 2003The Drosophila circadian clock consists of two interlocked transcriptional feedback loops. In one loop, dCLOCK/CYCLE activates period expression, and PERIOD protein then inhibits dCLOCK/CYCLE activity...
- User testing and stakeholder feedback contributed to the development of understandable and useful Summary of Findings tables for Cochrane reviewsSarah E Rosenbaum
Norwegian Knowledge Centre for the Health Services, St Olavs Plass, Oslo, Norway
J Clin Epidemiol 63:607-19. 2010..To develop a Summary of Findings (SoF) table for use in Cochrane reviews that is understandable and useful for health professionals, acceptable to Cochrane Collaboration stakeholders, and feasible to implement...
- A fast, robust and tunable synthetic gene oscillatorJesse Stricker
Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA
Nature 456:516-9. 2008..oscillator was designed using a previously modelled network architecture comprising linked positive and negative feedback loops...
- Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolinE Carballo
Office of Clinical Research and Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Science 281:1001-5. 1998..These findings identify TTP as a component of a negative feedback loop that interferes with TNF-alpha production by destabilizing its messenger RNA...
- What is feedback in clinical education?J M Monica van de Ridder
Centre for Research and Development, University Medical Centre Utrecht, Utrecht, The Netherlands
Med Educ 42:189-97. 2008b>Feedback is important in clinical education. However, the medical education literature provides no consensual definition of feedback...
- A systematic review of the use of theory in randomized controlled trials of audit and feedbackHeather L Colquhoun
Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital, General Campus, 501 Smyth Road, Centre for Practice Changing Research, Box 201B, Ottawa, Ontario K1H 8L6, Canada
Implement Sci 8:66. 2013Audit and feedback is one of the most widely used and promising interventions in implementation research, yet also one of the most variably effective...
- Effects of remote feedback in home-based physical activity interventions for older adults: a systematic reviewHilde Geraedts
Center for Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Patient Educ Couns 91:14-24. 2013To evaluate the literature on effectiveness of remote feedback on physical activity and capacity in home-based physical activity interventions for older adults with or without medical conditions...
- Factors contributing to inappropriate ordering of tests in an academic medical department and the effect of an educational feedback strategySpiros Miyakis
Third Department of Internal Medicine, University of Athens, Sotiria General Hospital, Athens, Greece
Postgrad Med J 82:823-9. 2006To identify factors contributing to laboratory overutilisation in an academic medical department, and to assess the effect of an educational feedback strategy on inappropriate test-ordering behaviour.
- Separable neural mechanisms contribute to feedback processing in a rule-learning taskK Zanolie
Leiden University Institute for Psychological Research LU IPR, Leiden University, The Netherlands
Neuropsychologia 46:117-26. 2008..appropriately to environmental demands, it is important to monitor ongoing action and process performance feedback for possible errors...
- Faculty staff perceptions of feedback to residents after direct observation of clinical skillsJennifer R Kogan
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Med Educ 46:201-15. 2012..Given the inaccuracy of self-assessment, the provision of external feedback to residents about their clinical skills is necessary for the development of expertise...
- Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasionThomas M Kitzing
Institute of Pharmacology, University of Heidelberg, 69120 Heidelberg, Germany
Genes Dev 21:1478-83. 2007..Our results reveal that Dia1 is necessary for LPA-stimulated Rho/ROCK signaling and bleb-associated cancer cell invasion. Thus, Dia1-dependent RhoA activation constitutes a positive feedback mechanism to modulate cell behavior.
- Mechanical feedback as a possible regulator of tissue growthBoris I Shraiman
Kavli Institute for Theoretical Physics, Kohn Hall, University of California, Santa Barbara, CA 93106, USA
Proc Natl Acad Sci U S A 102:3318-23. 2005..stress, and we propose that dependence of the rate of cell division on local stress could provide an "integral-feedback" mechanism stabilizing uniform growth...
- Visual feedback distortion in a robotic environment for hand rehabilitationBambi Roberts Brewer
Carnegie Mellon University, Pittsburgh, PA, United States
Brain Res Bull 75:804-13. 2008..Our research uses a paradigm called visual feedback distortion in which the visual feedback corresponding to force or distance is gradually changed by an ..
- Enhanced negative feedback responses in remitted depressionDiane L Santesso
Department of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA
Neuroreport 19:1045-8. 2008Major depressive disorder (MDD) is characterized by hypersensitivity to negative feedback that might involve frontocingulate dysfunction...
- Multiple parietal reach regions in humans: cortical representations for visual and proprioceptive feedback during on-line reachingFlavia Filimon
Department of Cognitive Science, University of California, San Diego, La Jolla, California 92093, USA
J Neurosci 29:2961-71. 2009Reaching toward a visual target involves at least two sources of information. One is the visual feedback from the hand as it approaches the target...
- Feedforward, horizontal, and feedback processing in the visual cortexV A Lamme
Graduate School of Neurosciences, Department of Medical Physics, University of Amsterdam, The Netherlands
Curr Opin Neurobiol 8:529-35. 1998..These modulations reflect lateral interactions within areas and feedback from higher to lower areas...
- Frequency control of motor patterning by negative sensory feedbackJessica Ausborn
Institute of Neurobiology, Ulm University, D 89069 Ulm, Germany
J Neurosci 27:9319-28. 2007..key role in the generation of behavior by providing the nervous system with information about the environment and feedback about body movements such that motor output can continuously be adapted to changing circumstances...
- Vocalization-induced enhancement of the auditory cortex responsiveness during voice F0 feedback perturbationRoozbeh Behroozmand
Speech Physiology Laboratory, Department of Communication Science and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA
Clin Neurophysiol 120:1303-12. 2009The present study investigated whether self-vocalization enhances auditory neural responsiveness to voice pitch feedback perturbation and how this vocalization-induced neural modulation can be affected by the extent of the feedback ..
- Learning-induced enhancement of feedback inhibitory synaptic transmissionInbar Brosh
Departments of Neurobiology and Biology, Faculty of Sciences, University of Haifa 31905, Israel
Learn Mem 16:413-6. 2009..We suggest that learning is accompanied by long-lasting enhancement of synaptic inhibition onto excitatory neurons, thus compensating for the increase of excitation in these neurons...
- Self-esteem modulates medial prefrontal cortical responses to evaluative social feedbackLeah H Somerville
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Cereb Cortex 20:3005-13. 2010..As such, self-esteem may bias neural responses to positive and negative social feedback across individuals...
- It was not MY fault: event-related brain potentials in active and observational learning from feedbackChristian Bellebaum
Institute of Cognitive Neuroscience, Department of Neuropsychology, Ruhr University of Bochum, Universitaetsstraße 150, Bochum, Germany
Cereb Cortex 20:2874-83. 2010Performance feedback during learning is accompanied by a negative event-related potentials (ERP) component, the feedback-related negativity (FRN), which codes a reward prediction error...
- p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional programLisa Y Pang
CRUK Cell Signalling Unit, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, UK
Cell Cycle 10:932-50. 2011The regulation of p53 activity through the MDM2 negative feedback loop is driven in part by an extrinsic ATM-pulse that maintains p53 oscillations in response to DNA damage...
- Neural correlates of auditory feedback control in humanA Toyomura
Research Institute of Science and Technology for Society, Japan Science and Technology Agency, Japan
Neuroscience 146:499-503. 2007Auditory feedback plays an important role in natural speech production...
- CPR quality improvement during in-hospital cardiac arrest using a real-time audiovisual feedback systemBenjamin S Abella
Department of Emergency Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Resuscitation 73:54-61. 2007..We hypothesized that real-time feedback during CPR would improve the performance of chest compressions and ventilations during in-hospital cardiac arrest.
- Translational feedback regulation of the gene for L35 in Escherichia coli requires binding of ribosomal protein L20 to two sites in its leader mRNA: a possible case of ribosomal RNA-messenger RNA molecular mimicryMaude Guillier
Institut de Biologie Physico Chimique, Unité Propre de Recherche 9073 du Centre National de la Recherche Scientifique, Paris, France
RNA 8:878-89. 2002..However L20 can bind to each site independently in vitro. One site is similar to the L20-binding site on 23S rRNA. Here we propose that L20 recognizes its mRNA and its rRNA in similar way...
- Effective desynchronization by nonlinear delayed feedbackOleksandr V Popovych
Institute of Medicine, Research Center Julich, 52425 Julich, Germany
Phys Rev Lett 94:164102. 2005We show that nonlinear delayed feedback opens up novel means for the control of synchronization. In particular, we propose a demand-controlled method for powerful desynchronization, which does not require any time-consuming calibration...
- Contribution of sensory feedback to ongoing ankle extensor activity during the stance phase of walkingJ Maxwell Donelan
Department of Physiology, Centrre for Neuroscience, University of Alberta, Edmonton T6G 2H7, Alberta, Canada
Can J Physiol Pharmacol 82:589-98. 2004Numerous investigations over the past 15 years have demonstrated that sensory feedback plays a critical role in establishing the timing and magnitude of muscle activity during walking...
- Social feedback and the emergence of leaders and followersJennifer L Harcourt
Department of Zoology, University of Cambridge, Cambridge, UK
Curr Biol 19:248-52. 2009..We conclude that leadership in this case is reinforced by positive social feedback.
- Postnatal maternal separation during the stress hyporesponsive period enhances the adrenocortical response to novelty in adult rats by affecting feedback regulation in the CA1 hippocampal fieldG Biagini
Department of Biomedical Sciences, University of Modena, Italy
Int J Dev Neurosci 16:187-97. 1998....
- Human glucocorticoid feedback inhibition is reduced in older individuals: evening studyC W Wilkinson
Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington 98108, USA
J Clin Endocrinol Metab 86:545-50. 2001..To confirm this finding and to determine whether aging-related changes in feedback responsiveness are exaggerated near the time of the circadian nadir in adrenocortical secretion, we performed a ..
- Individual-level interventions to reduce college student drinking: a meta-analytic reviewKate B Carey
Center for Health and Behavior, Syracuse University, Syracuse, NY 13244 2340, USA
Addict Behav 32:2469-94. 2007..suggest that individual, face-to-face interventions using motivational interviewing and personalized normative feedback predict greater reductions in alcohol-related problems...
- CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loopQun He
Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, 75390, USA
Genes Dev 20:2552-65. 2006The eukaryotic circadian oscillators consist of circadian negative feedback loops. In Neurospora, it was proposed that the FREQUENCY (FRQ) protein promotes the phosphorylation of the WHITE COLLAR (WC) complex, thus inhibiting its activity...
- Improving quality improvement using achievable benchmarks for physician feedback: a randomized controlled trialC I Kiefe
University of Alabama at Birmingham, 1717 11th Ave S, MT 700, Birmingham, AL 35205 4785, USA
JAMA 285:2871-9. 2001Performance feedback and benchmarking, common tools for health care improvement, are rarely studied in randomized trials...
- Brain states: top-down influences in sensory processingCharles D Gilbert
The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Neuron 54:677-96. 2007..are determined by the interactions between multiple cortical areas and the modulation of intrinsic circuits by feedback connections...
- The effects of spike frequency adaptation and negative feedback on the synchronization of neural oscillatorsB Ermentrout
Department of Mathematics, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neural Comput 13:1285-310. 2001..The shunting behavior is captured in a simple two-variable reduced model that arises near certain types of bifurcations. A one-dimensional map is derived from the simplified model...
- Self-controlled feedback is effective if it is based on the learner's performanceSuzete Chiviacowsky
School of Physical Education, Federal University of Pelotas, Brazil
Res Q Exerc Sport 76:42-8. 2005The study follows up on the contention that self-controlled feedback schedules benefit learning because they are more tailored to the performers' needs than externally controlled feedback schedules (Chiviacowsky & Wulf, 2002)...
- Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lungPao Tien Chuang
Cardiovascular Research Institute, University of California, San Francisco, California 94143, USA
Genes Dev 17:342-7. 2003..Our studies focused on Hip1 in the lung. Here, a dynamic interaction between Hh and fibroblast growth factor (Fgf) signaling, modulated at least in part by Hip1, controls early lung branching...
- Adaptation to visual feedback delays in manual tracking: evidence against the Smith Predictor model of human visually guided actionR C Miall
Behavioural Brain Sciences, School of Psychology, University of Birmingham, B15 2TT Birmingham, UK
Exp Brain Res 172:77-84. 2006We report adaptation to delayed visual feedback during a manual tracking task, testing the nature of the adapted responses with frequency analysis...
- Dorsal anterior cingulate cortex shows fMRI response to internal and external error signalsClay B Holroyd
Department of Psychology, Green Hall, Princeton University, Princeton, New Jersey 08544, USA
Nat Neurosci 7:497-8. 2004..imaging (fMRI) experiment, participants learned to select between two response options by trial-and-error, using feedback stimuli that indicated monetary gains and losses...
- Postural feedback responses scale with biomechanical constraints in human standingSukyung Park
Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 2125, USA
Exp Brain Res 154:417-27. 2004We tested whether human postural responses can be described in terms of feedback control gains, and whether these gains are scaled by the central nervous system to accommodate biomechanical constraints...
- Positive feedback and noise activate the stringent response regulator rel in mycobacteriaKamakshi Sureka
Department of Chemistry, Bose Institute, Kolkata, India
PLoS ONE 3:e1771. 2008..two distinct peaks corresponding to low (L) and high (H) expression states, and further establish that a positive feedback loop involving the mprAB operon along with stochastic gene expression are responsible for the phenotypic ..
- Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expressionStéphanie Decherf
Departement Regulations, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7221, Evolution des Regulations Endocriniennes, Museum national d histoire naturelle, Paris, France
Proc Natl Acad Sci U S A 107:4471-6. 2010..These facts led us to test the hypothesis that energy homeostasis should require negative feedback by T(3) on Mc4r expression...
- Spatial positive feedback at the onset of mitosisSilvia D M Santos
Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305 5174, USA
Cell 149:1500-13. 2012..Positive feedback loops regulate the activation of Cdk1-cyclin B1 and help make the process irreversible and all-or-none in ..
- A systematic review of selected interventions for worksite health promotion. The assessment of health risks with feedbackRobin E Soler
National Center for Health Marketing, CDC, Atlanta, Georgia 30333, USA
Am J Prev Med 38:S237-62. 2010..report provides recommendations on the effectiveness of interventions that use an Assessment of Health Risks with Feedback (AHRF) when used alone or as part of a broader worksite health promotion program to improve the health of ..
- Training with virtual visual feedback to alleviate phantom limb painCatherine Mercier
Center for Cognitive Neuroscience, Bron, France
Neurorehabil Neural Repair 23:587-94. 2009Performing phantom movements with visual virtual feedback, or mirror therapy, is a promising treatment avenue to alleviate phantom limb pain. However the effectiveness of this approach appears to vary from one patient to another.
- Error and feedback processing in children with ADHD and children with Autistic Spectrum Disorder: an EEG event-related potential studyYvonne Groen
Department of Psychiatry, University Medical Center Groningen, University of Groningen, P O Box 660, 9700 AR Groningen, The Netherlands
Clin Neurophysiol 119:2476-93. 2008....
- Adjuvant Treatment Decision Making for Lung CancerJamie Studts; Fiscal Year: 2006..Only when patients understand the necessary information about the risks and benefits of each treatment option will they be able to make informed treatment decisions that are consistent with their values. [unreadable] [unreadable]..
- Ensemble Disruption of the GnRH-LH-Testosterone AxisJohannes Veldhuis; Fiscal Year: 2007..Interpreted from this vantage, published literature, laboratory experiments, background data and ensemble feedback/feed forward simulations predict that hydroandrogenemia in aging men could arise nonexclusively by way of: (i) ..
- Mechanistic bases for age-related androgen deficiencyJohannes Veldhuis; Fiscal Year: 2007..HYPOTHESIS III: Reduced negative feedback by testosterone, which unleashes high-frequency, low- amplitude and irregular LH release...
- THE AGING GH AXIS IN POSTMENOPAUSAL WOMENJohannes Veldhuis; Fiscal Year: 2005..Hypothesis III: Estrogen add back can override GH's autonegative feedback restraint of GH secretion...
- ENSEMBLE MODEL OF STRESS ACTH-ADRENAL AXISJohannes Veldhuis; Fiscal Year: 2005..sheep, horse and human, the stress-responsive corticotropic-adrenal axis can be viewed as a dynamically adaptive feedback system supervised by key brain (hypothalamic) regulatory centers...
- Analytical Reconstruction of Feedback Signaling in Aging MenJohannes Veldhuis; Fiscal Year: 2008..provided by applicant): Self-adaptive (homeostatic) biological systems operate via repeated incremental feedback and feed forward signaling adjustments to maintain species, gender and age-defined physiological norms...
- An Internet-based intervention for problem drinkingJohn Cunningham; Fiscal Year: 2008..be randomly assigned to be sent a World Wide Web page Internet address and password for the personalized alcohol feedback program or to a no intervention control group...
- Motion Sensor Array for Vestibular-deficient IndividualsConrad Wall; Fiscal Year: 2005....
- Patient Feedback Effectiveness StudyPaul Crits Christoph; Fiscal Year: 2008..The proposed study tests the effectiveness of one Ql system - Patient Feedback (PF) - at increasing outpatient group therapy attendance and self-reported abstinence...
- Combined Treatment for GADPaul Crits Christoph; Fiscal Year: 2008..Data analysis will focus on differential rate of change (mixed model analyses) for the two groups. If promising results are obtained for combined treatment, a larger more definitive trial will be planned. [unreadable] [unreadable]..
- NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATIONESTHER GARDNER; Fiscal Year: 2008..activity in S-I confirms or rebuts the subject[unreadable]s expectation of haptic features, and provides feedback needed for error correction...
- Skill acquisition in older adultsRachael Seidler; Fiscal Year: 2009....
- NEUROINFORMATICS AND EYE-HAND COORDINATIONESTHER GARDNER; Fiscal Year: 2005....
- Persistence and Desistence in Heavy Drinking and ViolenceHelene R White; Fiscal Year: 2010..Within a 2-year period, we will be able to make a significant contribution to the scholarly literature and provide data to be used in the development of targeted pre,vention programs. ..
- COMMUNITY-FRIENDLY MANUAL GUIDED DRUG COUNSELINGPaul Crits Christoph; Fiscal Year: 2004..The proposed treatment development work will include (1) obtaining feedback on the new treatment manuals by a sample of 15 community-based drug counselors, (2) evaluating whether a group of ..
- A Spiking Model of Hippocampus for Guiding BehaviorMichael Hasselmo; Fiscal Year: 2006..U., which focuses on modeling operant tasks used in experimental studies of drug self-administration phenomena, in work supported by a supplement to a previous grant from NIDA. [unreadable] [unreadable]..
- Female Anti-Problem Drinking Group & Campus InitiativesJoseph LaBrie; Fiscal Year: 2006..Campus awareness will increase and campus culture will be changed. Evaluation/analysis plan is included. ..
- Reducing Antimicrobial Use Associated with Ventilator Associated Pneumonia and CaSARA ELIZABETH COSGROVE; Fiscal Year: 2010..and guidelines for catheter removal and dissemination of these materials via pocket cards and posters as well as feedback both to individual physicians about appropriate use of catheters and antimicrobials and to nurses regarding ..
- The Process of Group Therapy for Cocaine DependencePaul Crits Christoph; Fiscal Year: 2007..degree of patient participation, quality of participation, quality of the therapeutic alliance, and frequency of feedback (and positive feedback), as assessed in group drug counseling sessions, as predictors of treatment outcome...
- THERAPY DEVELOPMENT FOR MENTALLY ILL DRUG ABUSERSKate Carey; Fiscal Year: 2003..This award would allow the applicant protected time (teaching relief and summer support) to continue to develop her research on the treatment of substance abuse among the severely mentally ill. ..
- Portable low-cost glove for functional hand measuresLISA SIMONE; Fiscal Year: 2007..unreadable] [unreadable]..
- Examining Psychosocial Mediators of Exercise BehaviorBeth Lewis; Fiscal Year: 2007..theoretical constructs) are most effective for increasing physical activity, which will have an important public health impact given that this will likely lead to more efficacious and less costly interventions. [unreadable] [unreadable]..
- Cognitive Neurogenetics of SchizophreniaCameron Carter; Fiscal Year: 2008..The work proposed in this application has the potential to have important implications for developing behavioral genetic tools to isolate the genes that cause schizophrenia. ..
- Alcohol Research Collabortive: Peer ProgramsMary Larimer; Fiscal Year: 2007..the efficacy of the Alcohol EDU web-based educational intervention in comparison to web-delivered motivational feedback and assessment-only, in reducing alcohol use and consequences of high-risk freshmen; 3) Test the longer-term ..
- Clinical Investigation of E.coli Biofilm Formation in the Human BladderBARBARA TRAUTNER; Fiscal Year: 2007..No effective strategy exists to prevent CAUTI in persons who require ongoing catheter use. Identifying genes that are required to cause CAUTI will lead to new strategies to prevent this illness. [unreadable] [unreadable] [unreadable]..
- Reflex control of multi-joint mechanics following strokeERIC PERREAULT; Fiscal Year: 2007..A small, complementary animal study will be performed to investigate possible mechanisms underlying the actions of tizanidine. [unreadable] [unreadable]..
- Steering Flexible Needles in Soft TissueALLISON MARIKO OKAMURA; Fiscal Year: 2010....
- Randomized Trial of Tinnitus Retraining TherapyRichard Tyler; Fiscal Year: 2008..If TRT is shown to be no more effective than masking or counseling, professionals should focus on more efficient therapeutic techniques. This experiment will test the neurophysiological model of tinnitus. [unreadable] [unreadable]..
- Dietary Adherence Enhancement in Peritoneal DialysisMARY SEVICK; Fiscal Year: 2007..Measurements will occur as baseline, 4 months, and 8 months for both groups. [unreadable] [unreadable]..
- Untethered Home Therapy SystemJOSEPH GIUFFRIDA; Fiscal Year: 2008..By monitoring EMG and kinetic signals we will discriminate therapy tasks, monitor compliance time, and provide feedback. Additionally, movements, coordination patterns, and/or EMG will be used as inputs to an algorithm trained to ..
- Evaluating Nicotine Lozenges for Treatment of Smokeless Tobacco AddictionJon Ebbert; Fiscal Year: 2009..No drug therapies have been shown to be effective for helping smokeless tobacco users quit for good. The purpose of this study is to test drugs that can be used to help smokeless tobacco users quit for good. ..
- Modeling the Role of Priming in Executive ControlGordon Logan; Fiscal Year: 2009..The first aim will establish the validity of the model, the second will establish its limits and set the stage for a general model of executive control. ..
- Treatment and/or Prevention of Urinary Tract InfectionsBARBARA TRAUTNER; Fiscal Year: 2008..An agent to prevent and treat UTI that does not encourage microbial resistance would have a significant impact on public health. [unreadable] [unreadable] [unreadable]..
- The Value of CPOE in Pediatric Inpatient Units and Its Impact on Safety and WorkBen Tzion Karsh; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Improving Weight Loss Outcomes in African AmericansJamy Ard; Fiscal Year: 2008..The proposed training and research will provide Dr. Ard with the necessary skills and experience to advance his career to an independent investigator in obesity in special populations such as African Americans. ..
- Electrocorticographic Study of Categorical Phoneme Perception in the Human TemporEdward Chang; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Theoretical analysis of the effects of aging on memory and reaction timeRoger Ratcliff; Fiscal Year: 2010....
- Treatment of Child Physical Abuse: An Effectiveness TrialDavid Kolko; Fiscal Year: 2010..This study will provide initial data on the transportability and adoption of EBTs in community settings serving the child welfare system. ..
- Regulation of vascular smooth muscle calcium sensitivityPaul H Ratz; Fiscal Year: 2010..The Specific Aim of this study will be to test the hypothesis that ROK and PKCzeta both mediate KCI- induced Ca sensitization of FA, and that iPLA2 and PI3K are required as upstream activators of ROK and PKCzeta. ..
- Novel Active Repressor Model of Human LDL-Receptor RegulationJohannes Veldhuis; Fiscal Year: 2008..This would represent a new treatment approach for patients with atherosclerotic disease. [unreadable] [unreadable] [unreadable] [unreadable]..
- Cerebromicrovascular disease in elderly with diabetesVera Novak; Fiscal Year: 2010..This study will provide new data and biomarkers on cerebral perfusion and functional outcomes in type 2 DM, that can be used to initialize the efforts to implement brain protection as a new target for prevention of DM complications. ..
- Synaptic plasticity in the medial superior oliveLUISA SCOTT; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Adenosine and Nitric Oxide DeficiencyItalo Biaggioni; Fiscal Year: 2004....
- REGULATION OF DETRUSOR SMOOTH MUSCLE CONTRACTIONPAUL RATZ; Fiscal Year: 2005..Collectively, these studies will provide new insights into the cellular mechanisms regulating DSM contractions. ..
- EGO DEPLETION PATTERNS AND SELF-CONTROL FAILUREROY BAUMEISTER; Fiscal Year: 2001..The fourth section will explore several implications and applications of the depletion of self: vulnerability to loss of self-esteem from ego threat; prejudice; procrastination; and overeating. ..
- ENHANCING ADHD RX EFFECTIVENESS BY PEDIATRICS & SCHOOLSLeonard Bickman; Fiscal Year: 2001..An important element of this study is that it will not only examine the effectiveness of the intervention on individual children but will examine the effect community-wide. ..
- CUTANEOUS CONTROL OF EXPLORATORY HAND MOVEMENTALLAN SMITH; Fiscal Year: 2001..Prehensile movements of the hand use cutaneous feedback to adjust grip forces to the weight and friction of a handled object to minimize slip on the skin...
- IMPROVING PEDIATRICIANS' USE OF AD/HD GUIDELINESLeonard Bickman; Fiscal Year: 2003....
- PHARMACOLOGIC PROBES IN NEURALLY-MEDIATED SYNCOPEItalo Biaggioni; Fiscal Year: 2003..These studies will be directly applicable to the evaluation and treatment of patients with these incapacitating disorders. ..
- ADULT NEUROGENESIS & VOCAL PLASTICITY IN SONGBIRDSLUISA SCOTT; Fiscal Year: 2003..abstract_text> ..
- NEURONAL ORGANIZATION OF BASAL GANGLIACharles Wilson; Fiscal Year: 2003..This latter will allow us to determine whether there is an actual mismatch between physiological and anatomical estimates of connectivity (i.e. non-functional synaptic connections). ..
- Metacognition and Control in Human Learning MemoryJANET A METCALFE; Fiscal Year: 2010....
- ACTIONS OF ESTROGEN IN MATURING GRAAFIAN FOLLICLESJohannes Veldhuis; Fiscal Year: 2005..Understanding such fundamental interactions is important to the rational design of alternative strategies to interrupt normal and rescue impaired steroidogenesis in the maturing Graafian follicle and corpus luteum. ..
- Cognitive Neuroscience of SchizophreniaCameron Carter; Fiscal Year: 2005....
- Time course of learning perceptual pop-out in V1 and V2Matthew Smith; Fiscal Year: 2006..In addition, knowledge of the limits of visual cortical plasticity are important in understanding diseases such as amblyopia, in which there are known changes in the cortex as a result of a visual impairment. ..
- Intelligent Task Assist Device for Motor Control in Cerebral PalsyJOSEPH GIUFFRIDA; Fiscal Year: 2006..The system should help subjects complete activities of daily living, thereby increasing their independence and societal participation. [unreadable] [unreadable]..
- Dynamical Assessment of Cerebral AutoregulationVera Novak; Fiscal Year: 2007..Therefore, this project may have substantial socioeconomic impact. [unreadable] [unreadable] [unreadable]..
- COORDINATION OF SITTING UPPaul Cordo; Fiscal Year: 2001..The vertical forces produced on the support surface will be recorded along with segmental kinematics and muscle (EMG) activity. ..
- Age Effects in Attention & Memory: Process DissociationsLARRY JACOBY; Fiscal Year: 2006..The aim of experiments in that series is to show that changes in neural activation result from training that reduces age difference in vulnerability to interference...
- Functional Substrates of Long-Term Motor LearningScott Grafton; Fiscal Year: 2006..Specific Aim 1: Characterize the internal representation of a continuous motor skill as a function of feedback and control mechanisms. [unreadable] [unreadable] Specific Aim 2: Identify convergence of functional anatomy...
- PDE-5 Inhibition in HIV+ and HIV- MenRaymond Rosen; Fiscal Year: 2005..Key personnel for the project are Raymond C. Rosen, Ph.D., Professor of Psychiatry and Medicine at UMDNJ, who will serve as PI, and Joseph Catania, PhD, co-PI, from the AIDS Research Institute at UCSF. ..
- Brief Dental Office Intervention with Tobacco QuitlineJon Ebbert; Fiscal Year: 2005..S. adult population smoking; and 3) 75% of smokers quitting for at least one day or longer because they are trying to quit. ..
- Neural Systems Underlying Sign Language ProductionKaren Emmorey; Fiscal Year: 2009..abstract_text> ..
- Volunteer Activities on Long-Term Care ResidentsHon Yuen; Fiscal Year: 2002..It is expected that findings will support the activity theory of aging and validate the beneficial effects of residents in LTC facilities participating in structured volunteer activities. ..
- Effectiveness Trial of Attention Shaping for SchizophreniaSteven M Silverstein; Fiscal Year: 2010....
- Problem Solving Environment for Modeling the Cell CycleJohn Tyson; Fiscal Year: 2002..and some outstanding collaborators (Sible and Cross, experimental cell cycle research; Kitano and Bolouri, software development for molecular cell biology; and Kohn, bioinformatics of mammalian cell cycle controls). ..
- Oral Health in People with Systemic SclerosisHon Yuen; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- PITUITARY CELLS TO STUDY MALE INFERTILITYSTEPHEN WINTERS; Fiscal Year: 2002..abstract_text> ..
- G PROTEIN MEDIATED CA++ SENSITIZATION IN SMOOTH MUSCLEToshio Kitazawa; Fiscal Year: 2002....
- Mechanism of Ca2+ Sensitization in Smooth MuscleToshio Kitazawa; Fiscal Year: 2006..abstract_text> ..
- BEHAVIORAL/PHARMACOLOGIC TREATMENT OF ALCOHOLISMWilliam Miller; Fiscal Year: 2004..However, each study site has provided site-specific information on the budget, budget justifications, listing of key personnel, consultant/consortium agreements, and human subjects sections of their respective proposals. ..
- PROGRAMMATIC TREATMENT INNOVATION RESEARCHWilliam Miller; Fiscal Year: 2004..abstract_text> ..
- Proprioceptive feedback gain modulation during movementMark Shapiro; Fiscal Year: 2008..The two main mechanisms by which movement is produced are predictive feedforward control and sensory feedback control. The interplay of these two mechanisms in single-joint goal-oriented movements will be studied...
- MOVING MOTIVATIONAL INTERVIEWING INTO PRACTICEWilliam Miller; Fiscal Year: 2002..Two promising training enhancement procedures (individualized feedback to clinicians, and reinforced practice through individual consultations) will be evaluated via a design combining ..
- Acceptance Therapy During Methadone DetoxificationAngela Stotts; Fiscal Year: 2007..Effective treatment provided in conjunction with detoxification from agonist medication could result in significant decreases in the substantial health and social costs associated with chronic opiate dependence. ..