wit and humor


Summary: The faculty of expressing the amusing, clever, or comical or the keen perception and cleverly apt expression of connections between ideas that awaken amusement and pleasure. (From Random House Unabridged Dictionary, 2d ed)

Top Publications

  1. ncbi Alleviating stress with humour: a literature review
    Winifred Chinery
    Southend Hospital
    J Perioper Pract 17:172, 174, 176-9 passim. 2007
  2. ncbi Humor in hospice care: who, where, and how much?
    Kathleen N Adamle
    Kent State University Kent, Ohio, USA
    Am J Hosp Palliat Care 22:287-90. 2005
  3. ncbi [Emotional intelligence, social support and affect regulation]
    Ramiro Verissimo
    Serviço de Psicologia Médica, Faculdade de Medicina, Universidade do Porto, Porto
    Acta Med Port 18:345-52. 2005
  4. ncbi The phenomenon of resilience in crisis care mental health clinicians
    Karen Leigh Edward
    School of Nursing, Faculty of Health and Behavioural Sciences, Deakin University, Burwood, Australia
    Int J Ment Health Nurs 14:142-8. 2005
  5. ncbi The experience of a good day: a phenomenological study to explain a good day as experienced by a newly qualified RN
    Carole Jackson
    Florence Nightingale School of Nursing and Midwifery, Kings College London, James Clarke Maxwell Building, 57 Waterloo Road, London SE1 8WA, UK
    Accid Emerg Nurs 13:110-21. 2005
  6. ncbi Nurse-patient communication: an exploration of patients' experiences
    Catherine McCabe
    Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland
    J Clin Nurs 13:41-9. 2004
  7. ncbi Responding to patient-initiated humor: guidelines for practice
    Kathleen Adamle
    College of Nursing, Kent State University, Kent, OH 44242, USA
    Home Healthc Nurse 24:638-44. 2006
  8. ncbi Therapeutic play: developing humor in the nurse-patient relationship
    Martha Greenberg
    Pace University, Lienhard School of Nursing, Pleasantville, NY, USA
    J N Y State Nurses Assoc 34:25-31. 2003
  9. ncbi Interactions between nurses and men admitted with chest pain
    Alan K White
    School of Health and Community Care, Leeds Metropolitan University, Calverly Street, Leeds LS1 3HE, UK
    Eur J Cardiovasc Nurs 2:47-55. 2003
  10. ncbi Humor in medicine
    Howard J Bennett
    Department of Pediatrics, The George Washington University Medical Center, Washington, DC, USA
    South Med J 96:1257-61. 2003

Detail Information

Publications241 found, 100 shown here

  1. ncbi Alleviating stress with humour: a literature review
    Winifred Chinery
    Southend Hospital
    J Perioper Pract 17:172, 174, 176-9 passim. 2007
  2. ncbi Humor in hospice care: who, where, and how much?
    Kathleen N Adamle
    Kent State University Kent, Ohio, USA
    Am J Hosp Palliat Care 22:287-90. 2005
    ..These findings were consistent regardless of hospice setting. Humor was spontaneous and frequent, and instances of humorous interactions were a prevalent part of everyday hospice work...
  3. ncbi [Emotional intelligence, social support and affect regulation]
    Ramiro Verissimo
    Serviço de Psicologia Médica, Faculdade de Medicina, Universidade do Porto, Porto
    Acta Med Port 18:345-52. 2005
    ..These findings are consistent with the hypothesis that social support can be considered, somehow, as a way of mood repair; and thus not surprisingly is also associated with more Positive Affects and Sensation Seeking...
  4. ncbi The phenomenon of resilience in crisis care mental health clinicians
    Karen Leigh Edward
    School of Nursing, Faculty of Health and Behavioural Sciences, Deakin University, Burwood, Australia
    Int J Ment Health Nurs 14:142-8. 2005
  5. ncbi The experience of a good day: a phenomenological study to explain a good day as experienced by a newly qualified RN
    Carole Jackson
    Florence Nightingale School of Nursing and Midwifery, Kings College London, James Clarke Maxwell Building, 57 Waterloo Road, London SE1 8WA, UK
    Accid Emerg Nurs 13:110-21. 2005
    ..They need to ensure that all levels of knowledge are addressed before they can carry out care. Additionally, the team dynamics and the way the team work together had a significant effect on the day...
  6. ncbi Nurse-patient communication: an exploration of patients' experiences
    Catherine McCabe
    Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland
    J Clin Nurs 13:41-9. 2004
    ..Nurses are frequently described in the literature as poor communicators, however, very few studies have examined patients' experiences of how nurses communicate...
  7. ncbi Responding to patient-initiated humor: guidelines for practice
    Kathleen Adamle
    College of Nursing, Kent State University, Kent, OH 44242, USA
    Home Healthc Nurse 24:638-44. 2006
  8. ncbi Therapeutic play: developing humor in the nurse-patient relationship
    Martha Greenberg
    Pace University, Lienhard School of Nursing, Pleasantville, NY, USA
    J N Y State Nurses Assoc 34:25-31. 2003
    ..This study offers nurses and others involved in professional relationships an explanation of the development of humor as an alternative healing-caring strategy...
  9. ncbi Interactions between nurses and men admitted with chest pain
    Alan K White
    School of Health and Community Care, Leeds Metropolitan University, Calverly Street, Leeds LS1 3HE, UK
    Eur J Cardiovasc Nurs 2:47-55. 2003
    ..This paper reports on an analysis of the interactions that occurred between nurses and men admitted with acute chest pain...
  10. ncbi Humor in medicine
    Howard J Bennett
    Department of Pediatrics, The George Washington University Medical Center, Washington, DC, USA
    South Med J 96:1257-61. 2003
  11. ncbi The professional role of breast cancer nurses in multi-disciplinary breast cancer care teams
    Z Amir
    Macmillan Practice Development Unit, School of Nursing, Midwifery and Health Visiting, University of Manchester, Gateway House, Piccadilly South, Manchester M60 7LP, UK
    Eur J Oncol Nurs 8:306-14. 2004
    ..Cancer nurses including the BCNs should develop and participate in programmes of research in line with cancer legislation in order to build an evidence base that ultimately supports their unique role...
  12. ncbi Using cooperative inquiry and clinical supervision to improve practice
    Emrys Jenkins
    Centre for Philosophy, Humanities and Law in Health Care, School of Health Science, University of Wales, Swansea
    Br J Community Nurs 12:63-9. 2007
    ..Our relationships and humour help us to seek more holistic appreciation of experience than solitary self-reflection can provide, and we need dedicated time for this social, more critical appreciation...
  13. ncbi Sustaining well-being and enabling recovery: the therapeutic effect of nurse friendliness on clients and nursing environments
    Rene Geanellos
    School of Nursing, Family and Community Health, University of Western Sydney, Hawkesbury, New South Wales
    Contemp Nurse 19:242-52. 2005
    ..In revealing the phenomenon of nurse friendliness, this study findings add to knowledge regarding the therapeutic potential and significance of nurse-client relationships...
  14. ncbi 'Am I being over-sensitive?' Women's experience of sexual harassment during medical training
    Susan W Hinze
    Department of Sociology, Case Western Reserve University, Cleveland, OH 44106 7124, USA
    Health (London) 8:101-27. 2004
    ..I conclude with a discussion of how reforms in medical education must tend to the gendered, everyday realities of women and men in training...
  15. ncbi The use of humor and its influences on spirituality and coping in breast cancer survivors
    Paige Johnson
    Department of Breast Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Oncol Nurs Forum 29:691-5. 2002
    ..To describe patients' perspectives concerning the use of humor in their care and recovery...
  16. ncbi Can patients tell when they are unwanted? "Turfing" in residency training
    Catherine V Caldicott
    Center for Bioethics and Humanities, SUNY Upstate Medical University, 725 Irving Avenue, Suite 406, Syracuse, NY 13210, USA
    Patient Educ Couns 56:104-11. 2005
    ..This study aims to discover if "turfed" patients (TPs) experience their hospitalizations differently from patients whose admissions are perceived more favorably by their physicians...
  17. ncbi Working with patients who have big burns: exploring the perspectives of senior medical staff of different professional groups
    Claudia Camhi
    Hillingdon Child, Family, and Adolescent Consultation Service, Uxbridge, UK
    J Burn Care Res 28:187-94. 2007
    ..Finally, they reflected on intragroup ways of support generated by their burns team and they highlight the use of humor and the use informal networks as ways of support...
  18. ncbi Improving patient care and quality of life after laryngectomy/glossectomy
    M Dobbins
    ENT Department, Royal Gwent Hospital, Newport, South Wales
    Br J Nurs 14:634-40. 2005
    ..And then when you wake up properly that's the bit I always say you wish you were dead. That's when you wish you had died.'..
  19. ncbi Psychological well-being of adults with acquired hearing impairment
    Anne Sofie Helvik
    Ear, Nose and Throat Department, St Olav s University Hospital of Trondheim, Norway
    Disabil Rehabil 28:535-45. 2006
  20. ncbi Experiencing the "good life": literary views of craniofacial conditions and quality of life
    Ronald P Strauss
    Department of Dental Ecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7450, USA
    Cleft Palate Craniofac J 42:14-8. 2005
    ..Many adults with craniofacial conditions find ways to live with their difference and to succeed using the measures they construct...
  21. ncbi The relationship between prayer, health behaviors, and protective resources in school-age children
    Lynn Rew
    The University of Texas at Austin, Austin, Texas 78701 1499, USA
    Issues Compr Pediatr Nurs 27:245-55. 2004
    ..In addition, children who prayed frequently reported significantly higher levels of positive health behaviors than children who never prayed. These two groups of children did not significantly differ in their levels of perceived stress...
  22. ncbi Coping and emotional adjustment following traumatic brain injury
    Katie Anson
    School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne, Australia
    J Head Trauma Rehabil 21:248-59. 2006
    ..To examine the association between coping style and emotional adjustment following traumatic brain injury...
  23. ncbi Comparison of three modes of measuring stress, coping, and humor in school-age children
    Rachel T Fouladi
    Department of Psychology, Simon Fraser University Burnaby, BC, Canada
    J Nurs Meas 14:79-98. 2006
    ..This study suggests the importance of the continued examination of the impact of mode of questionnaire administration when assessing these and other domains of well-being in school-age children...
  24. ncbi The comprehension of humorous materials by adolescents with high-functioning autism and Asperger's syndrome
    David M Emerich
    Kenton County Public Schools, Erlanger Kentucky, USA
    J Autism Dev Disord 33:253-7. 2003
    ..Examination of the error patterns revealed that subjects with autism had difficulty handling surprise and coherence within humorous narratives...
  25. ncbi Increase in dermcidin-derived peptides in sweat of patients with atopic eczema caused by a humorous video
    Hajime Kimata
    Department of Allergy, Moriguchi Keijinkai Hospital, Moriguchi City, Osaka Prefecture, Japan
    J Psychosom Res 62:57-9. 2007
    ..However, the levels of DCD-derived peptide in sweat were decreased in patients with atopic eczema (AE). The effect of viewing a humorous video on the levels of DCD-derived peptide was studied...
  26. ncbi Positive psychological measure: constructing and evaluating the reliability and validity of a Chinese Humor Scale applicable to professional nursing
    Chia Jung Hsieh
    School of Nursing, Taipei Medical University, Taiwan
    J Nurs Res 13:206-15. 2005
    ..Further research is needed to explore more fully the implications of humor in nursing...
  27. ncbi Kinematical analysis of emotionally induced facial expressions in patients with obsessive-compulsive disorder
    R Mergl
    Department of Psychiatry, Ludwig Maximilians Universitat Munchen, Laboratory of Clinical Neurophysiology, Munchen, Germany
    Psychol Med 33:1453-62. 2003
    ..To investigate subtle motor dysfunction, kinematical analysis of emotional facial expressions can be used. Our aim was to investigate facial movements in response to humorous film stimuli in OCD patients...
  28. ncbi Nurses' and patients' perceptions of dignity
    Ken Walsh
    Department of Clinical Nursing, University of Adelaide, South Australia, Australia
    Int J Nurs Pract 8:143-51. 2002
    ..The characteristics that patients attributed to dignity and its maintenance included respect, privacy, control, choice, humour and matter-of-factness...
  29. ncbi The impact of staff case manager-case management supervisor relationship on job satisfaction and retention of RN case managers
    Tierney D Hogan
    Regence BlueShield, Seattle, WA, USA
    Lippincotts Case Manag 10:246-53. 2005
    ..Staff case managers need to have a voice at work and feel empowered, and a supervisor's leadership style can influence job satisfaction and retention in their staff...
  30. ncbi Youth Resilience Framework for reducing health-risk behaviors in adolescents
    Lynn Rew
    School of Nursing, The University of Texas at Austin, 78701, USA
    J Pediatr Nurs 18:379-88. 2003
    ..This framework incorporates a developmental approach to address precursors and health-risk behaviors that may be amenable to early health-promoting interventions...
  31. ncbi Making fun of patients: medical students' perceptions and use of derogatory and cynical humor in clinical settings
    Delese Wear
    Northeastern Ohio Universities College of Medicine, Rootstown, Ohio, USA
    Acad Med 81:454-62. 2006
    ..quot; This study examines one dimension of this phenomenon: how medical students perceive and use derogatory and cynical humor directed at patients...
  32. ncbi Coping responses of emergency physicians and nurses to the 2003 severe acute respiratory syndrome outbreak
    D H Phua
    Emergency Department, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433
    Acad Emerg Med 12:322-8. 2005
    ..The study hospital introduced psychosocial interventions to help HCWs. This study aimed to examine the coping strategies adopted by the emergency department (ED) HCWs who cared for the SARS patients...
  33. ncbi [Study on psychiatric disorders and defensive process assessed by the "defense style questionnaire" in sterile males SAMPLE consulting in andrology]
    M Bellone
    Psychiatre assistant des Hôpitaux, CHRU de Lille, F59037 Lille
    Encephale 31:414-25. 2005
    ..These are a clinical entity recently introduced in the quantitative psychopathology research. The defense style questionnaire (DSQ) is a psychometric scale used in common practice in order to measure the defense styles...
  34. ncbi [Humor as an additional component of psychological and psychiatric diagnostics in children and adolescents: concept of a humor-diagnostic model]
    Joachim Schreiner
    Kinder und Jugendpsychiatrische Universitätsklinik und Poliklinik, Basel
    Prax Kinderpsychol Kinderpsychiatr 53:468-82. 2004
    ..g. humorous drawings) can be used. Central in using humor as a diagnostic assessment device is the knowledge of humor development and of the relations between psychiatric illnesses and humor...
  35. ncbi Humor coping, health status, and life satisfaction among older adults residing in assisted living facilities
    B G Celso
    Florida State University, Florida, USA
    Aging Ment Health 7:438-45. 2003
    ..Humor as a coping strategy seems to be available to older adults who are in better health...
  36. ncbi An investigation of worry and sense of humor
    William E Kelly
    Department of Counseling, University of Nevada, Las Vegas, USA
    J Psychol 136:657-66. 2002
    ..The results are discussed in relation to W. E. Kelly and M. J. Miller's (1999) cognitive model of worry and worry as a coping strategy...
  37. ncbi Adolescent humor and its relationship to coping, defense strategies, psychological distress, and well-being
    Sarah J Erickson
    Psychology Department, Logan Hall, University of New Mexico, Albuquerque, NM 87131, USA
    Child Psychiatry Hum Dev 37:255-71. 2007
  38. ncbi Humor. An antidote for terrorism
    Elaine Anne Pasquali
    Adelphi University, USA
    J Holist Nurs 21:398-414. 2003
    ..Awareness of the phases of emotional adjustment, associated humor styles, and ways to incorporate therapeutic humor into crisis management approaches are essential for effectively using humor as an antidote for terrorism...
  39. ncbi Coping sense of humor reduces effects of stereotype threat on women's math performance
    Thomas E Ford
    Department of Sociology, Western Michigan University, Kalamazoo 49008, USA
    Pers Soc Psychol Bull 30:643-53. 2004
    ..Women higher in coping sense of humor performed better because they felt less anxiety while taking the test...
  40. ncbi Documenting and explaining the common AAB pattern in music and humor: establishing and breaking expectations
    Paul Rozin
    Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
    Emotion 6:349-55. 2006
    ..We also provide experimental evidence that the AAB pattern in jokes is maximally effective in producing a humor response in participants...
  41. ncbi Native American humor: implications for transcultural care
    Ruth A Dean
    Faculty of Nursing, University of Manitoba, Canada
    J Transcult Nurs 14:62-5. 2003
    ..If non-Native nurses and caregivers are to deliver culturally competent care, they would do well to familiarize themselves with the benefits that humor has to offer as well as the pitfalls they may encounter...
  42. ncbi Supportive-expressive group therapy: the transformation of existential ambivalence into creative living while enhancing adherence to anti-cancer therapies
    David W Kissane
    Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Psychooncology 13:755-68. 2004
    ..This promotes compliance with anti-cancer treatments, including both the initiation of and perseverance with chemotherapy. This mechanism could prove to be a potentially important pathway in promoting longer survival...
  43. ncbi Social cognition in frontal lobe epilepsy
    Annette Farrant
    Department of Psychology, Institute of Psychiatry, London, UK
    Epilepsy Behav 7:506-16. 2005
    ..Hence the patients with FLE exhibited impairments on tests of social cognition following a distinct pattern, with relatively preserved ToM, but impaired humor appreciation and ability to detect emotional expression...
  44. ncbi Rare or remarkable microfungi from Oaxaca (south Mexico)--Part II
    N Ale-Agha
    Department of General Botany, University Duisburg Essen, Universitätsstr 5, 45117 Essen, Germany
    Commun Agric Appl Biol Sci 73:147-55. 2008
    ..Shoemaker on Prosopis juliflora (Sw.) DC.; Cylindrocladium scoparium Morg. on Ficus benjamina L.; Acremonium sp. on Bougainvillea sp. All specimens are located in the herbarium ESS. Mycotheca Parva collection G.B. Feige and N. Ale-Agha...
  45. ncbi [Synthetic biocompatible degradable material for juvenile bone cyst treatment]
    P Gal
    Klinika detské chirurgie, ortopedie a traumatologie FN Brno
    Acta Chir Orthop Traumatol Cech 76:495-500. 2009
    ..These cysts are usually diagnosed between; five and twenty years of age outside this age range their occurrence is rare...
  46. ncbi Sentinel lymph node biopsy has no benefit for patients with primary cutaneous melanoma metastatic to a lymph node: an assertion based on comprehensive, critical analysis: part I
    N S Medalie
    Ackerman Academy of Dermatopathology, New York, NY 10021, USA
    Am J Dermatopathol 25:399-417. 2003
    ..There is no justification, whatsoever, for the procedure, scientifically or practically, and for that reason it should be abandoned, without delay, now...
  47. ncbi Modelling the effect of ethanol on growth rate of food spoilage moulds
    Philippe Dantigny
    Laboratoire de Microbiologie, UMR Universite de Bourgogne INRA 1232, ENS BANA, 1 Esplanade Erasme, F 21000 Dijon, France
    Int J Food Microbiol 98:261-9. 2005
    ..harzianum (E(max) 2.14%) and P. variotii (E(max) 6.43%). Ethanol would appear an effective additional barrier to inhibit fungal growth in food products and would represent an interesting alternative to the use of preservatives...
  48. ncbi Extranodal natural killer/T-cell lymphoma, nasal-type
    Dimitrios Chorianopoulos
    Department of Pulmonary Medicine, Athens Medical School, Sotiria General Hospital, Athens, Greece
    Skinmed 8:56-8. 2010
    ..Although the lung lesions had diminished at that time, the patient develope paraplegia, his clinical course rapidly deteriorated, and he eventually died...
  49. ncbi Transurethral resection versus minimally invasive treatments of benign prostatic hyperplasia: results of treatments. Our experience
    Daniele Minardi
    Institute of Urology, Polytechnic University of the Marche Region, Medical School, Ancona, Italy
    Arch Ital Urol Androl 76:11-8. 2004
    ..In this non-randomized prospective study the results of standard TURP (Transurethral Resection of the Prostate) versus other minimally invasive treatments were compared...
  50. ncbi Islet isolation from juvenile porcine pancreas after 24-h hypothermic machine perfusion preservation
    Michael J Taylor
    Cell and Tissue Systems, N Charleston, SC, USA
    Cell Transplant 19:613-28. 2010
    ..The edema appears to aid in enzymatic digestion, producing a greater yield and purity of islets compared with pancreas subjected to 24 h of static cold storage...
  51. ncbi [INFORNUT process: validation of the filter phase-FILNUT--and comparison with other methods for the detection of early hospital hyponutrition]
    J L Villalobos Gámez
    Equipo de Soporte Nutricional, Hospital Virgen de la Victoria, Malaga, Espana
    Nutr Hosp 21:491-504. 2006
    ..The high prevalence justifies the need for early detection from admission. There several classical screening tools that show important limitations in their systematic application in daily clinical practice...
  52. ncbi [Morphology of the glottis and perceptiv-acoustic characteristic of the voice and speech after extended fronto-lateral epiglotttoplasty]
    Czesława Tarnowska
    Katedra i Klinika Otolaryngologii i Onkologii Laryngologicznej PAM
    Otolaryngol Pol 63:496-503. 2009
  53. pmc The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm
    D Kraemer
    Laboratory of Cell Biology, Rockefeller University, Howard Hughes Medical Institute, New York, NY 10021
    Proc Natl Acad Sci U S A 91:1519-23. 1994
    ..In agreement with previously proposed nomenclature for nucleoporins, we propose the alternative term nup214 (nucleoporin of 214 kDa) for the CAN protein...
  54. ncbi Wit: using drama to teach first-year medical students about empathy and compassion
    Linda A Deloney
    College of Medicine, University of Arkansas for Medical Sciences, 4301 West Markham, Slot 556, Little Rock, AR 72205, USA
    Teach Learn Med 15:247-51. 2003
    ..Training in empathy and compassion can foster altruism in medical students...
  55. ncbi Cilia in the head of hornets: form and function
    Jacob S Ishay
    Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel
    Microsc Res Tech 67:71-8. 2005
    ..In summary, ciliary structures are involved in the hornet in gravity sensing, in acoustical communication and in light sensing, i.e., with some similarity with what happens in vertebrates in the inner ear and in the photoreceptor...
  56. ncbi Effect of maternal lead exposure on craniofacial ossification in rat fetuses and the role of antioxidant therapy
    H A Saleh
    Department of Anatomy, Faculty of Medicine, King Abdul Aziz University, 21589 Jeddah, Kingdom of Saudi Arabia
    Anat Histol Embryol 38:392-9. 2009
  57. ncbi [Geriatric management of the frail elderly with hip fracture may improve their clinical outcome]
    J I Gonzalez-Montalvo
    Unidad de Geriatría Hospital Universitario La Paz Madrid
    Med Clin (Barc) 116:1-5. 2001
  58. ncbi Priming of D1-dopamine receptor responses: long-lasting behavioral supersensitivity to a D1-dopamine agonist following repeated administration to neonatal 6-OHDA-lesioned rats
    H Criswell
    Biological Sciences Research Center, School of Medicine, University of North Carolina, Chapel Hill 27599
    J Neurosci 9:125-33. 1989
    ..In addition, responses to indirect-acting agonists were enhanced in rats that had been primed with a D1-dopamine agonist when compared wit responses in unprimed animals.(ABSTRACT TRUNCATED AT 250 WORDS)..
  59. ncbi Eosinophilic pustular folliculitis in infancy: not a distinctive inflammatory disease of the skin
    Mirjana Ziemer
    Department of Dermatology, Friedrich Schiller University of Jena, Germany
    Am J Dermatopathol 27:443-55. 2005
  60. ncbi [Anxiety and depression in cardiology patients: how to diagnose, how to treat?]
    C Herrmann-Lingen
    Klinik für Psychosomatik und Psychotherapie, Universitat Gottingen
    Herz 26:326-34. 2001
  61. ncbi A tribute to the life and accomplishments of Birdwell Finlayson
    Lawrence L Yeung
    Department of Urology, University of Florida, College of Medicine, Gainesville, Florida 32610 0247, USA
    J Urol 179:842-6; discussion 846. 2008
    ..We researched his life and accomplishments to provide a historical account of his career...
  62. ncbi Nomenclature for very superficial squamous cell carcinoma of the skin and of the cervix: a critique in historical perspective
    Galen M Kessler
    Ackerman Academy of Dermatopathology, 145 E 32 St, Fl 10, New York, NY 10016, USA
    Am J Dermatopathol 28:537-45. 2006
    ..In that way, physicians charged with management of patients can plan therapy rationally...
  63. ncbi Sequencing and mutational analysis of the non-coding regions of influenza A virus
    Leyi Wang
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, United States
    Vet Microbiol 135:239-47. 2009
    ..Our study reaffirms the importance of NCRs in influenza virus replication and further analysis of their roles will lead to better understanding of influenza pathogenesis...
  64. ncbi Improved preservation of warm ischemic livers by hypothermic machine perfusion with supplemented University of Wisconsin solution
    Shailendra Jain
    Department of Mechanical Engineering and Engineering Science, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA
    J Invest Surg 21:83-91. 2008
    ..05) higher in UW group. Histology showed well-preserved hepatic structure in the SUW group. In conclusion, this study suggests that HMP with SUW solution has the potential to restore and preserve livers with extended WIT...
  65. ncbi Standards for humidification and filtration devices
    John Stevens
    London W4 3UR, United Kingdom
    Respir Care Clin N Am 12:203-32. 2006
    ..While caveat emptor must always be the shibboleth of the purchaser, statutory or advisory regulations are no defense for an incompetent user...
  66. pmc MPW: the Metabolic Pathways Database
    E Selkov
    Intitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow Region, Russia
    Nucleic Acids Res 26:43-5. 1998
    ..An auxiliary database of compound names and structures, encoded in the SMILES format, is maintained to unambiguously connect the pathways to the chemical structures of their intermediates...
  67. ncbi Isolation and characterisation of a novel stress-inducible PDI-family gene from Aspergillus niger
    D J Jeenes
    Department of Genetics and Microbiology, Institute of Food Research, Colney, Norwich, UK
    Gene 193:151-6. 1997
    ..Transcription of tigA is induced 2-3-fold after treatment with tunicamycin, an inhibitor of N-linked glycosylation. Strains overexpressing a heterologous protein show no increased tigA mRNA levels...
  68. pmc Lower Miocene stratigraphy along the Panama Canal and its bearing on the Central American Peninsula
    Michael Xavier Kirby
    Center for Tropical Paleoecology and Archaeology, Smithsonian Tropical Research Institute, Balboa, Republic of Panama
    PLoS ONE 3:e2791. 2008
  69. ncbi Influence of fractionated irradiation on neutrophilic granulocyte function
    Alfred Haidenberger
    Department of Radiotherapy, Leopold Franzens University Innsbruck, Austria
    Strahlenther Onkol 179:45-9. 2003
    ..In clinical practice, by contrast, fractionated irradiation is applied. Therefore, the aim of the current study was to verify the influence of fractionated radiation therapy on granulocyte function...
  70. ncbi [Leptin in patients wit nephrotic syndrome]
    M Merta
    1 interní klinika, 1 LF UK a VFN, U nemocnice 2, 128 08 Praha 2, Czech Republic
    Sb Lek 104:279-84. 2003
  71. ncbi Achieving glycemic control in young children with type 1 diabetes: approaches, pitfalls and new technologies
    Philip A Gruppuso
    Brown Medical School, Hasbro Children s Hospital, Providence, RI, USA
    Med Health R I 86:107-11. 2003
    ..All technologies have improved our ability to attain glycemic control, thereby reducing the risk of long-term complication in even our youngest patients...
  72. ncbi A novel technique for laparoscopic or robotic partial nephrectomy: feasibility study
    Ronney Abaza
    Robotic Urologic Surgery, Ohio State University Medical Center and James Cancer Hospital, Columbus, Ohio 43210, USA
    J Endourol 22:1715-9. 2008
    ..We investigate the feasibility of a novel approach with the potential to minimize ischemia time as well as maximize precision of tumor excision...
  73. ncbi Intravenous immunoglobulin therapy influences T cell adhesion to extracellular matrix in women with a history of recurrent spontaneous abortions
    M Jerzak
    Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław
    Am J Reprod Immunol 44:336-41. 2000
    ..In addition, to evaluate a small-dose intravenous immunoglobulin (IVIG) therapy influences on T cell adhesion to ECM...
  74. pmc Impulsivity, frontal lobes and risk for addiction
    Fulton Timm Crews
    Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
    Pharmacol Biochem Behav 93:237-47. 2009
    ..This review will examine the relationships between impulsivity and executive function behaviors to changes in cortical structure during alcohol dependence and recovery...
  75. ncbi Effect of exogenous administration of melatonin and growth hormone on pro-antioxidant functions of the liver in aging male rats
    R A Kireev
    Department Biochemistry and Biophysics, Saratov State University, Saratov, Russia
    J Pineal Res 42:64-70. 2007
    ..In conclusion, GH and melatonin treatment seems to have beneficial effects against age-induced damage in the liver...
  76. pmc Regulation of beta-galactoside transport and accumulation in heterofermentative lactic acid bacteria
    A H Romano
    Department of Molecular and Cell Biology, University of Connecticut, Storrs 06268
    J Bacteriol 169:5589-96. 1987
    ..brevis, although this lactobacillus lacked a functional phaosphoenolpyruvate-dependent phosphortransferase system for glucose, 2-deoxyglucose, or TMG...
  77. ncbi The economic costs of alcohol, tobacco and illicit drugs in Canada, 1992
    E Single
    Canadian Centre on Substance Abuse, University of Toronto, Ontario, Canada
    Addiction 93:991-1006. 1998
    ..AIMS, DESIGN AND SETTING: The economic costs of alcohol, tobacco and illicit drugs in Canadian society in 1992 are estimated utilizing a cost-of-illness framework and recently developed international guidelines...
  78. ncbi Age-dependent susceptibility of CNS glial populations in situ to the antimetabolite 6-aminonicotinamide
    J M Krum
    Department of Anatomy, George Washington University Medical Center, Washington, DC 20037, USA
    Mol Chem Neuropathol 26:79-94. 1995
    ..The results suggest the presence of heterogeneous populations of glia whose preferred use of the hexose monophosphate pathway is predicated on both the age of the animal and their location in the CNS...
  79. ncbi Interaction of some benzothiadiazine diuretics with beta-cyclodextrin
    S I Abdel-Rahman
    Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Egypt
    Acta Pharm Hung 60:69-75. 1990
    ..The variation in the extent of binding between each of the three drugs and beta-cyclodextrin was attributed to their variation in molecular volume, partition coefficient and electrostatic properties of the binding sites...
  80. pmc Dynamical changing patterns of histological structure and ultrastructure of liver graft undergoing warm ischemia injury from non-heart-beating donor in rats
    Yi Ma
    Organ Transplantation Center, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, Guangdong Province, China
    World J Gastroenterol 12:4902-5. 2006
    ..To investigate the histological and ultra-structural characteristics of liver graft during different of warm ischemia time (WIT) in rats and to predict the maximum limitation of liver graft to warm ischemia...
  81. ncbi [Intraoperative complications of corticosubcortical mapping]
    P Teixidor
    Hospital Germans Trias y Pujol, Badalona, Barcelona
    Neurocirugia (Astur) 21:99-107. 2010
    ..Regarding complications, respiratory complications are the most common and the most dangerous, as they can influence in the surgical procedure for difficult cases...
  82. ncbi Invasive pneumococcal disease in Greenland
    J Christiansen
    Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland
    Int J Circumpolar Health 63:214-8. 2004
    ..The purpose of the present study was to evaluate the incidence and outcome of pneumococcal infections in Greenland with special reference to serotypes...
  83. ncbi Usefulness of monitoring congestive heart failure by multiple impedance vectors
    Dorin Panescu
    St Jude Medical, Sunnyvale, CA, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:5668-70. 2008
    ..We investigated trends in intrathoracic impedance measured between multiple implanted electrodes for monitoring pulmonary edema secondary to congestive heart failure (CHF) in an experimental model...
  84. ncbi Progressive deceleration in growth as an early sign of delayed puberty in boys
    M V Du Caju
    Department of Pediatrics, University Hospital Antwerp, Belgium
    Horm Res 54:126-30. 2000
    ..To describe the prepubertal growth pattern in boys with delayed puberty...
  85. ncbi Synergistic effect of cold and warm ischemia time on postoperative graft outcome in human liver transplantation
    Eishi Totsukali
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki Japan
    Hepatogastroenterology 51:1413-6. 2004
    ..The aim of this study was to determine whether simultaneously prolonged CIT and WIT was associated with early graft outcome after clinical OLT...
  86. ncbi Prevention of warm ischemic injury by neuropeptide bombesin in small bowel transplantation
    O Kimura
    Division of Surgery, Children s Research Hospital, Kyoto Prefectural University of Medicine, 465 Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 0841, Japan
    Transplant Proc 38:1794-5. 2006
    ..This study investigated whether preoperative administration of neuropeptide bombesin (BBS) had a protective effect against IR/I and subsequent acute rejection...
  87. ncbi [Vena cava superior syndrome: surgical treatment of the thrombosis of the superior vena cava after implantation of a hemodialysis catheter--a case report and review of the literature]
    Laszlo Lenard
    Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, Szívgyógyászati Klinika, Pecs
    Orv Hetil 149:29-34. 2008
    ..Apropos of this case, the authors outline the causes of malignant, non-malignant and iatrogenic superior vena cava syndrome, furthermore the conservative, surgical and catheter therapy of the syndrome...
  88. ncbi Mini-incision for strictly retroperitoneal nephrectomy in living kidney donation vs flank incision
    A A Schnitzbauer
    University of Regensburg Medical Center, Department of Surgery, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Nephrol Dial Transplant 21:2948-52. 2006
    ..In this study, we investigated intra-operative and post-operative data on outcome following MIDN in comparison with ODN data...
  89. ncbi Molecular cloning of wound inducible transcript (wit 3.0) differentially expressed in edentulous oral mucosa undergoing tooth extraction wound-healing
    C Sukotjo
    Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, UCLA School of Dentistry, Box 951668, CHS B3 087, 90095 1668, USA
    J Dent Res 81:229-35. 2002
    ..0 alpha) and 253-(wit 3.0 beta) amino-acid-long peptides with the characteristics of an intracellular molecule. Analysis of these data may provide new clues to the molecular mechanism of edentulous mucosa formation...
  90. ncbi TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain
    Xiaoyan Zheng
    Department of Cell and Structural Biology, University of Illinois, Urbana, IL 61801, USA
    Cell 112:303-15. 2003
    ..We conclude that the Drosophila Activin signaling pathway mediates neuronal remodeling in part by regulating EcR-B1 expression...
  91. ncbi Biological and behavioral markers of alcohol sensitivity
    Kim Fromme
    Department of Psychology, The University of Texas at Austin, Austin, Texas 78712, USA
    Alcohol Clin Exp Res 28:247-56. 2004
    ..Dr. David Goldman provides concluding remarks...
  92. ncbi Genome encyclopedias and their use for comparative analysis of Rhodobacter capsulatus strains
    M Fonstein
    Department of Molecular Genetics and Cell Biology, The University of Chicago, IL 60637, USA
    Electrophoresis 19:469-77. 1998
    ..capsulatus in order to assign functions to unknown ORFs has been started. Preliminary data demonstrate the extreme convenience of the unique gene transfer agent (GTA) system to perform such work...
  93. ncbi Trans-sinusal maxillary distraction for correction of midfacial hypoplasia: long-term clinical results
    N Nadjmi
    Department of Cranio Maxillofacial Surgery, Eeuwfeestkliniek, Harmoniestraat 68, B 2018 Antwerpen, Belgium
    Int J Oral Maxillofac Surg 35:885-96. 2006
    ..Results up to 5 years after distraction showed considerable maxillary advancement with long-term stability. Ongoing growth of the facial skeleton must be considered when distraction osteogenesis is chosen in growing patients...
  94. ncbi Resilience: a concept analysis
    Marie Earvolino-Ramirez
    University of Texas at Austin, TX, USA
    Nurs Forum 42:73-82. 2007
    ..Concept analysis of resilience...
  95. pmc Sir Robert Hutchison (1871-1960) of London and the causes and treatment of rickets
    P M Dunn
    University of Bristol, Southmead Hospital, Southmead, Bristol BS10 5BN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F537-9. 2005
    ..His wisdom and wit educated and amused successive generations of students and doctors...
  96. ncbi Healing hearts: laughter and learning
    Melany Cueva
    Alaska Native Tribal Health Consortium, Anchor age, AK 99508, USA
    J Cancer Educ 21:104-7. 2006
    ..Cultural values of Alaska Native people acknowledge laughter as good medicine. It is heard in their words and stories...
  97. ncbi Role of vasodilation during normothermic machine perfusion of DCD porcine livers
    Ahmed Nassar
    Transplantation Center, Department of General Surgery, Cleveland Clinic, OH USA
    Int J Artif Organs 37:165-72. 2014
    ..We present our data on the impact of different vasodilators on DCD porcine livers preserved with NMP...
  98. ncbi Brominated flame retardants and other organobromines in Norwegian predatory bird eggs
    D Herzke
    Norwegian Institute for Air Research, NO 9296 Tromsø and NO 2027 Kjeller, Norway
    Chemosphere 61:441-9. 2005
    ..The naturally occurring halogenated compounds Q1, the dibromotrichloro monoterpene MHC-1, and 2,4,6-tribromoanisole (TBA) were detected in all of seven analysed samples except for one peregrine falcon egg...
  99. ncbi [Dimensional proposal to assess humor appreciation]
    Hugo Carretero Dios
    Universidad de Granada, Spain
    Psicothema 18:465-70. 2006
    ..Their judgments are presented and they are analyzed considering reviewed empirical and theoretical works. The results support some theoretical validity evidences of this dimensional proposal about humor appreciation...
  100. ncbi You can't use plywood: The perilous success of spirituality and medicine
    Arthur W Frank
    University of Calgary, Alberta, Canada
    Explore (NY) 1:142-3. 2005
    ..In doing so, he brings that which is intimately personal into a larger discourse that is social, political, and cultural. At the same time, he protects the inviolate intimacy granted to each individual on the threshold. Bravo!..
  101. ncbi [Songs in music therapy with children]
    Thomas Stegemann
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters des Universitätsklinikums Hamburg, Hamburg
    Prax Kinderpsychol Kinderpsychiatr 56:40-58. 2007
    ..Finally, the article reviews the diverse therapeutical functions of songs within the process of music therapy as well as essential qualifications for a music therapist...

Research Grants76

  1. Role of Peroxidasin in Glomerular Matrix Homeostasis
    Gautam Bhave; Fiscal Year: 2013
    ..Ultimately, Dr. Bhave hopes to translate his seminal biochemical discovery into an independent line of investigation examining the role of peroxidasin in matrix remodeling and expansion in renal disease. ..
  2. Functional Studies of Variants of the Bipolar Risk Gene CACNA1C in Human Neurons
    JEN PAN; Fiscal Year: 2013
  3. Adherence intervention to promote optimal use of insulin pumps in adolescents wit
    Kimberly Driscoll; Fiscal Year: 2013
  4. Targeted delivery of osteoinductive molecules to biologic HA in bone grafts
    Jennifer L Bain; Fiscal Year: 2012
    ..By developing a method of anchoring these important proteins back to this commercially available bone we hope to increase the regenerative capacity of allograft bone comparable to the level of autogenous bone. ..
  5. Metformin as a novel chemopreventive agent for prostate cancer
    Xin Li; Fiscal Year: 2013
    ..e. those with PIN or high-grade PIN). The novel combined cancer prevention therapy using metformin and mTOR inhibitors proposed in this study may display promising synergistic efficacy and will be translational to clinical application. ..
  6. Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action
    Daniel Shoskes; Fiscal Year: 2013
    ..We hope to show that CyA can be an effective therapy for recalcitrant IC/PBS which can be safely administered with appropriate monitoring and identify which patients benefit most from treatment ..
    Samuel Klein; Fiscal Year: 2012
    ..We aim to determine the effects of surgical induced weight loss on glucose metabolism as it relates to the duration of T2DM diagnosis (recent vs. longstanding). ..
  8. In vivo observations of transcription at single-nucleotide resolution
    MATTHEW HERBERT LARSON; Fiscal Year: 2013
    ..pylori) and Chlamydia trachomatis (C. trachomatis), as well as providing a useful tool to probe the role transcriptional pausing in human cancer cells. ..
  9. Genetic Basis of Opioid Reward and Aversion in Mice
    Camron D Bryant; Fiscal Year: 2013
    ..I am also interested in the intersection between reward/aversion and pain pathways and would like to further explore this area of research as a future proposal. ..
  10. Genetic Basis of Opioid Reward and Aversion in Mice
    Camron D Bryant; Fiscal Year: 2012
    ..I am also interested in the intersection between reward/aversion and pain pathways and would like to further explore this area of research as a future application. ..
  11. Unmetabolized folic acid and retinoblastoma.
    Manuela A Orjuela; Fiscal Year: 2013
    ..Results of our study could significantly affect both public policy, and our understanding of pediatric carcinogenesis. ..
  12. Eosinophils and lung immunity to Pneumocystis
    Chad Steele; Fiscal Year: 2013
  13. Glycoproteins and Glycan-Binding IgGs: Biomarkers for Cancer and Inflammatory Di
    Hyesook Kim; Fiscal Year: 2013
    ..Identification of prostate cancer- specific glycans recognized by autoantibodies will lead to development of glycan-based therapeutics. ..
  14. Development of human thioredoxin as a mucolytic therapy for Cystic Fibrosis
    Peter B Heifetz; Fiscal Year: 2012
  15. HIV Testing and Educating Male Partners to Improve Maternal and Infant Outcomes
    Carey Farquhar; Fiscal Year: 2013
  16. Nicotine and the roles of nicotinic receptors in a rodent model of schizophrenia
    Russell W Brown; Fiscal Year: 2013
    ..The critical hypothesis tested is that adult rats neonatally treated with quinpirole wil self-administer more nicotine than animals neonatally treated with saline. ..
  17. Endogenous opioid activity and affective state in insulin resistant women
    Alison Renee Berent-Spillson; Fiscal Year: 2013
    ..The relationship between metabolic and mood disorders exemplifies the increasing importance of investigators with multidisciplinary expertise, and the ability to conduct research that traverses traditional disciplinary boundaries. ..
  18. ACE2 Deficiency: A new model of maternal and fetal growth restriction.
    Liliya M Yamaleyeva; Fiscal Year: 2013
    ..Specific Aim 3 will determine whether maternal or fetal ACE2 KO is necessary for the fetal weight restriction using embryo transfer. ..
  19. Mechanisms of Immune Evasion and Recognition in Human Syphilis
    ADRIANA RAQUEL CRUZ; Fiscal Year: 2013
  20. Interventions to Test the alpha 7 Nicotinic Receptor Model in Schizophrenia
    Stephen Deutsch; Fiscal Year: 2009
    ..If the results of this pilot trial are positive, the next steps will be a definitive trial and efforts to develop medications that combine the allosteric modulatory and agonist properties of the combination in a single molecule. ..
  21. Technology to Assess Vulnerable Older Adults with Cancer and Their Caregivers
    Arti Hurria; Fiscal Year: 2013
    ..Ultimately these data could serve as the basis for integrating technology into future clinical care and research studies of older adults wit cancer. ..
  22. Impact of Neprilysin on Islet Function
    Sakeneh Zraika; Fiscal Year: 2013
    ..These studies will delineate a novel role for islet and intestinal NEP in modulating [unreadable]-cell function, and will have significant implications for development of therapeutics to treat [unreadable]-cell dysfunction in diabetes. ..
  23. Grp94 targeted therapy for pancreatic ductal adenocarcinoma
    Soldano Ferrone; Fiscal Year: 2013
    ..C. Ferrone's access to her patients wit PDAC at Massachusetts General Hospital, Boston, MA, her newly acquired skills in conducting clinical trials, and by the fully human nature of the mAb W9. ..
  24. IL-2 scintigraphy as a guide to cancer immunotherapy
    SVETOMIR NENAD MARKOVIC; Fiscal Year: 2013
  25. PDRemote: Automated Telehealth Diagnostics for Remote Parkinson's Monitoring
    JOSEPH GIUFFRIDA; Fiscal Year: 2013
  26. IQGAP1 In Vascular Barrier Regulation During Acute Lung Injury
    Mallar Bhattacharya; Fiscal Year: 2013
  27. Interactive Effect of Environmental Exposures and Alcohol in the Navajo Birth Coh
    Johnnye L Lewis; Fiscal Year: 2013
    ..If the hypothesis is supported by the study outcomes, the findings would have impact beyond the current population. ..
  28. Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac Outcomes
    Donald Edmondson; Fiscal Year: 2013
  29. Flt3L Treatment of Pancreatic Cancer
    Joyce C Solheim; Fiscal Year: 2013
    ..By the completion of this project, it is our expectation that we will have obtained preclinical results on Flt3L therapy for pancreatic cancer that will facilitate the start of a clincal trial. ..
  30. Optogenetic Population Clamp to Study Long-term Plasticity in Vitro
    Robert J Butera; Fiscal Year: 2013
  31. Developing a Medical Biometric Identification System wit a Secure Database Networ
    Jason W Sohn; Fiscal Year: 2012
  32. Investigating the Neural Circuits of Itch
    SARAH ELIZABETH ROSS; Fiscal Year: 2013
    GARY G MATTHEWS; Fiscal Year: 2013
    ..The results of the project will significantly advance fundamental knowledge about the early steps in transmission of sensory information in both vision and hearing. ..
  34. Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients wit*
    Robert A Wise; Fiscal Year: 2013
    ..If CPAP at night is effective, it will represent an entirely new approach to treating asthma. (End of Abstract) ..
  35. Targeting Binge Eating to Prevent Weight Gain in College Students
    Ruth H Striegel; Fiscal Year: 2012
    ..The proposed work advances public health by developing and evaluating a new strategy for targeted prevention of obesity in young adults who binge eat, a group especially likely to experience rapid and significant weight gain. ..
  36. Lineage bias and clonal expansion of hematopoietic stem cell differentiation
    Rong Lu; Fiscal Year: 2013
    ..In addition, it will help me locate an independent research position and provide the initial support to prepare for my first R01 application. ..
  37. Infections in Hematopoietic Cell Transplant Recipients
    Michael J Boeckh; Fiscal Year: 2013
    ..The studies conducted under these aims have a high potential of advancing our knowledge of the spectrum of infectious complications, the genetic basis of diseases, and factors that affect outcome. (End of Abstract) ..
  38. Mechanistic Analysis of Age-Induced Changes in Protein Hemostasis
    ERIC JOHN SOLIS; Fiscal Year: 2013
    ..Further, we will explore the ability of engineered variation, leading to increased protein folding capacity, can prevent the age-induced accumulation of protein aggregates and extend lifespan. ..
  39. Predoctoral Training Program in Human Genetics
    David Valle; Fiscal Year: 2013
    ..The success of our graduates, who obtain postdoctoral positions in top laboratories and go on to productive academic careers in top universities, strongly supports this conclusion. ..
  40. A research and training program for junior clinicians in treating metastatic mela
    Harriet M Kluger; Fiscal Year: 2013
    ..In aim 2, I will mentor a junior faculty clinician in conducting a clinical trial of an antibody against an immune-checkpoint inhibitory molecule (PD-1), and development of a panel of predictive biomarkers. ..
  41. Identification of Inhibitors of the N-Terminal Region of the Androgen Receptor
    Matthew B Rettig; Fiscal Year: 2013
    ..Our objective subsequent to the successful execution of the proposed work is to select a lead optimized AR transcriptional inhibitor for rapid translation to early phas human trials in patients with metastatic CRPC. ..
  42. A Patient Advocate to improve real-world asthma management for inner city adults
    Andrea J Apter; Fiscal Year: 2013
  43. Oxidative stress and programmed death pathways: Cross talk in pancreatic cancer
    Addanki P Kumar; Fiscal Year: 2013
    ..These studies will provide a rational basis for developing alternative and complementary medicinal strategies for targeting pancreatic cancer. ..
  44. Examining Opportunity for Participation in Cancer Clinical Trials
    JESSICA ROSE REARDEN; Fiscal Year: 2013
    ..This application reflects the National Instituteof Nursing Research (NINR) strategic goals of promoting health for patients with chronic illness and eliminating health disparities. ..
  45. The Diagnosis and Treatment of Critical Illness Polyneuromyopathy in Patients wit
    Marc Moss; Fiscal Year: 2013
    ..This trial will establish the efficacy of the physical therapy programs that is currently performed for patients with acute respiratory failure in a non-evidence based manner across the United States. ..
  46. Neurocognitive Disinhibition and Cannabis Addiction: A Career Development Award
    Raul Gonzalez; Fiscal Year: 2010
    ..This will lead to future studies that may identify youth at risk for cannabis addiction and inform interventions. ..
  47. Promoting regeneration in muscular dystrophy with adipose derived stem cells.
    Gretchen A Meyer; Fiscal Year: 2013
    ..We will show that adipose-derived stem cells are a clinically viable cell source for promoting muscle regeneration and improving contractile performance in dystrophic muscle. ..
  48. CRCNS: Large Scale Brain Connectivity in HIV-Related Cognitive Impairment
    AXEL W E WISMUELLER; Fiscal Year: 2013
    ..We will publicly disseminate scientific results and research infrastructure resources, which will ensure the translational research effectiveness of our project for sustainable clinical and educational use. ..
  49. Mechanisms of Regulatory B Cell Function
    Bonnie N Dittel; Fiscal Year: 2013
    ..Characterization and functional analysis of a novel IgDlow-neg follicular Breg. ..
  50. Chronic Renal Insufficiency Cohort (CRIC) Study
    Akinlolu O Ojo; Fiscal Year: 2013
    ..Our Clinical Center will cooperate with other CRIC study awardees and the NIDDK in the implementation of study protocols and procedures to accomplish the specific aims outlined above. ..
  51. Pregnancy Outcomes in Women with Disabilities: Exploratory Research
    Beth A Mueller; Fiscal Year: 2013
  52. Defining the Role for Orexin Transmission in Nicotine Reinforcement
    JONATHAN ALAN HOLLANDER; Fiscal Year: 2013
    ..Collectively, these experiments will provide important insight into the psychobiological mechanisms underlying nicotine addiction, and promise to yield a novel therapeutic strategy for treating human smokers. ..
  53. Affective and Genetic Correlates of Amphetamine Response
    ADAM MATTHEW LEVENTHAL; Fiscal Year: 2013
  54. Impact of Alcohol on HIV Protease Inhibitor-induced ER Stress and Lipotoxicity
    HUIPING ROSE ZHOU; Fiscal Year: 2013
    ..abstract_text> ..
    John S Werner; Fiscal Year: 2010
    ..Fortype specifications, see on page6.) RESEARCH GRANT TABLE OF CONTENTS . i PageNumbers Face Page .,4 1 Description, ..
  56. The functional contribution and clinical value of ALCAM in cancer metastasis
    Celestial Jones-Paris; Fiscal Year: 2013
    ..In addition, the recruitment of both clinical as well as basic science mentors allows for a comprehensive perspective in the training program. ..
  57. PAHs: New Technologies and Emerging Health Risks
    David E Williams; Fiscal Year: 2013
    ..Accomplishing these goals will provide significant scientific advancement and improve the quality of life for impacted communities. ..
  58. Mobile Tools for Improving Treatment of High Risk Alcohol Use in Primary Care
    Susan A Stoner; Fiscal Year: 2012
    ..In order to promote uptake of SBI in primary care settings and streamline delivery of SBI, the proposed project would develop a web-based screening tool and mobile phone-based alcohol risk reduction intervention. ..
  59. Training in Fundamental Neuroscience
    MARK THOMAS WALLACE; Fiscal Year: 2013
    ..The program is currently home to 83 trainees and 64 training faculty. The proposal requests an increase in support from 7 to 10 slots and provides the rationale and justification for this request. ..
  60. Neurophysiology underlying neural representations of value
    C Daniel Salzman; Fiscal Year: 2013
    ..In those disorders, dysfunction in amygdala- prefrontal circuitry likely impairs the type of emotional flexibility required for normal mental health. ..
  61. Novel Molecular Tools for Imaging Synaptic Dynamics
    HAIG S KESHISHIAN; Fiscal Year: 2010
    ..As there are numerous neurological disorders that involve defects in synaptic growth, maintenance, and/or plasticity, these studies will contribute to a rational analysis of these disorders of the nervous system. ..
  62. A Novel Motivational Ecological Momentary Intervention for Anorexia Nervosa
    ..Relevant research, coursework, hands-on training, and mentorship will support the applicant's goal to become a research scientist in this area. ..
  63. Listeria Immunotherapy for Pancreatic and Ovarian Cancer
    Thomas Dubensky; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  64. Trafficking of BMP signals in neurons
    Guillermo Marques; Fiscal Year: 2007
    ..unreadable] [unreadable]..
    Robert Colbert; Fiscal Year: 2001
    ..Furthermore, they will essential to our determining how polymorphic gene products involved at different sites in the class I antigen processing pathway might interact to predispose certain individuals to JRA. ..
    Pascal Goldschmidt Clermont; Fiscal Year: 1999
  67. Sedation and Psychopharmacology in Critical care
    Marjolein de Wit; Fiscal Year: 2007
    ..Psychiatric morbidity will be assessed by administration of validated questionnaires. This study design creates a pathway for new understanding of the impact of sedation and the incidence of morbidity. ..
    Frank Jordan; Fiscal Year: 2004
    ASRU SINHA; Fiscal Year: 1990
    Lawrence Hunsicker; Fiscal Year: 1993
    ..In addition six regional nephrologists, 5 HMOs, and a clinic caring for low income patients have agreed to refer patients...
    Patricia Rodier; Fiscal Year: 2000
    ..Identification of a mutation underlying autism would allow a clinical test r the deficit and the creation of transgenic animals in which teratogens coul be tested for the potential to trigger the disease. ..
    MOHAN CHELLADURAI; Fiscal Year: 1993
    ..These studies will in the long term provide a biochemical basis for the hypothesized correlation between expression of PAA/PCA and metastatic potential...
  73. Using Affymetrix Microflora array to study microflora composition in children wit
    Oleg Paliy; Fiscal Year: 2009
    Alvin Schmaier; Fiscal Year: 1999
    ..The importance of these studies is that they could introduce a novel pharmacologic approach to prevent arterial thrombosis. ..
    Kerim Munir; Fiscal Year: 1991
    Bruce Craig; Fiscal Year: 1999
    ..We will investigate several difference screening and treatment programs for each type of diabetes. ..