scientific misconduct

Summary

Summary: Intentional falsification of scientific data by presentation of fraudulent or incomplete or uncorroborated findings as scientific fact.

Top Publications

  1. pmc Misconduct accounts for the majority of retracted scientific publications
    Ferric C Fang
    Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 109:17028-33. 2012
  2. pmc How many scientists fabricate and falsify research? A systematic review and meta-analysis of survey data
    Daniele Fanelli
    INNOGEN and ISSTI Institute for the Study of Science, Technology and Innovation, The University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 4:e5738. 2009
  3. ncbi Why and how do journals retract articles? An analysis of Medline retractions 1988-2008
    Elizabeth Wager
    Sideview, Princes Risborough, UK
    J Med Ethics 37:567-70. 2011
  4. ncbi Scientists behaving badly
    Brian C Martinson
    HealthPartners Research Foundation, 8100 34th Avenue South, PO Box 1524, Mailstop 21111R, Minneapolis, Minnesota 55440 1524, USA
    Nature 435:737-8. 2005
  5. ncbi Good publication practice for pharmaceutical companies
    Elizabeth Wager
    Sideview, Princes Risborough, Buckinghamshire, UK
    Curr Med Res Opin 19:149-54. 2003
  6. pmc Retraction rates are on the rise
    Murat Cokol
    EMBO Rep 9:2. 2008
  7. pmc A systematic review of research on the meaning, ethics and practices of authorship across scholarly disciplines
    Ana Marusic
    Department of Research in Biomedicine and Health, University of Split School of Medicine, Split, Croatia
    PLoS ONE 6:e23477. 2011
  8. ncbi Lack of involvement of medical writers and the pharmaceutical industry in publications retracted for misconduct: a systematic, controlled, retrospective study
    Karen L Woolley
    ProScribe Medical Communications, Noosaville, Queensland, Australia
    Curr Med Res Opin 27:1175-82. 2011
  9. ncbi What do mentoring and training in the responsible conduct of research have to do with scientists' misbehavior? Findings from a National Survey of NIH-funded scientists
    Melissa S Anderson
    Department of Educational Policy and Administration, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Acad Med 82:853-60. 2007
  10. ncbi Retractions in the scientific literature: do authors deliberately commit research fraud?
    R Grant Steen
    Medical Communications Consultants LLC, 103 Van Doren Place, Chapel Hill, NC 27517, USA
    J Med Ethics 37:113-7. 2011

Detail Information

Publications243 found, 100 shown here

  1. pmc Misconduct accounts for the majority of retracted scientific publications
    Ferric C Fang
    Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 109:17028-33. 2012
    ..The percentage of scientific articles retracted because of fraud has increased ∼10-fold since 1975. Retractions exhibit distinctive temporal and geographic patterns that may reveal underlying causes...
  2. pmc How many scientists fabricate and falsify research? A systematic review and meta-analysis of survey data
    Daniele Fanelli
    INNOGEN and ISSTI Institute for the Study of Science, Technology and Innovation, The University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 4:e5738. 2009
    The frequency with which scientists fabricate and falsify data, or commit other forms of scientific misconduct is a matter of controversy...
  3. ncbi Why and how do journals retract articles? An analysis of Medline retractions 1988-2008
    Elizabeth Wager
    Sideview, Princes Risborough, UK
    J Med Ethics 37:567-70. 2011
    ..Anecdotal evidence suggested a lack of consistency in journal policies and practices regarding retraction. In order to develop guidelines, we reviewed retractions in Medline to discover how and why articles were retracted...
  4. ncbi Scientists behaving badly
    Brian C Martinson
    HealthPartners Research Foundation, 8100 34th Avenue South, PO Box 1524, Mailstop 21111R, Minneapolis, Minnesota 55440 1524, USA
    Nature 435:737-8. 2005
  5. ncbi Good publication practice for pharmaceutical companies
    Elizabeth Wager
    Sideview, Princes Risborough, Buckinghamshire, UK
    Curr Med Res Opin 19:149-54. 2003
    ..We also hope that pharmaceutical companies and others involved in developing publications arising from sponsored clinical trials will endorse the guidelines...
  6. pmc Retraction rates are on the rise
    Murat Cokol
    EMBO Rep 9:2. 2008
  7. pmc A systematic review of research on the meaning, ethics and practices of authorship across scholarly disciplines
    Ana Marusic
    Department of Research in Biomedicine and Health, University of Split School of Medicine, Split, Croatia
    PLoS ONE 6:e23477. 2011
    ..The purpose of this systematic review was to evaluate evidence about authorship issues and provide synthesis of research on authorship across all research fields...
  8. ncbi Lack of involvement of medical writers and the pharmaceutical industry in publications retracted for misconduct: a systematic, controlled, retrospective study
    Karen L Woolley
    ProScribe Medical Communications, Noosaville, Queensland, Australia
    Curr Med Res Opin 27:1175-82. 2011
    ..e., not ghostwriters) or declared pharmaceutical industry support. The secondary objective was to investigate factors associated with misconduct retractions...
  9. ncbi What do mentoring and training in the responsible conduct of research have to do with scientists' misbehavior? Findings from a National Survey of NIH-funded scientists
    Melissa S Anderson
    Department of Educational Policy and Administration, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Acad Med 82:853-60. 2007
    ..The authors examine training in the responsible conduct of research and mentoring in relation to behaviors that may compromise the integrity of science...
  10. ncbi Retractions in the scientific literature: do authors deliberately commit research fraud?
    R Grant Steen
    Medical Communications Consultants LLC, 103 Van Doren Place, Chapel Hill, NC 27517, USA
    J Med Ethics 37:113-7. 2011
    ....
  11. ncbi The role of culture in research misconduct
    Mark S Davis
    Institute for the Study and Prevention of Violence, 230 Auditorium Building, Kent State University, Kent, OH 44242, USA
    Account Res 10:189-201. 2003
    ..Acknowledging the role of culture in the adherence to research ethics underscores the importance of education and training of both researchers and administrators in the responsible conduct of research and cultural diversity...
  12. pmc Misconduct policies in high-impact biomedical journals
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
    PLoS ONE 7:e51928. 2012
    ..This study assessed the prevalence and content policies of the most influential biomedical journals on misconduct and procedures for handling and responding to allegations of misconduct...
  13. ncbi How long does it take for the scientific literature to purge itself of fraudulent material?: the Breuning case revisited
    K M Korpela
    Department of Psychology, University of Tampere, Tampere, Finland
    Curr Med Res Opin 26:843-7. 2010
    ..It has been proposed that the scientific literature purges itself of articles known to be fraudulent. To test this, an investigation was carried out of post-retraction citations over a 19-year period in the Breuning case...
  14. ncbi Sociology. Scientific misconduct: do the punishments fit the crime?
    Barbara K Redman
    College of Nursing, Wayne State University, Detroit, MI, 48202 USA
    Science 321:775. 2008
  15. pmc Scientific misconduct from the perspective of research coordinators: a national survey
    Erica R Pryor
    School of Nursing, University of Alabama at Birmingham, Birmingham, AL 35294 1210, USA
    J Med Ethics 33:365-9. 2007
    To report results from a national survey of coordinators and managers of clinical research studies in the US on their perceptions of and experiences with scientific misconduct.
  16. ncbi Handling of scientific dishonesty in the Nordic countries. National Committees on Scientific Dishonesty in the Nordic Countries
    M Nylenna
    Research Council of Norway, Oslo
    Lancet 354:57-61. 1999
    Despite a widely recognised need, most countries still have no coherent system to deal with scientific misconduct. Committees have been established by the national medical research councils in Denmark (1992), Norway (1994), and Sweden (..
  17. doi Repairing research integrity
    Sandra L Titus
    Office of Research Integrity, 1101 Wootton Parkway, Suite 750, Rockville, Maryland 20852, USA
    Nature 453:980-2. 2008
  18. pmc The importance of organizational justice in ensuring research integrity
    Brian C Martinson
    HealthPartners Research Foundation HPRF, Minneapolis, MN 55440 1524, USA
    J Empir Res Hum Res Ethics 5:67-83. 2010
    ..Thus, perceptions of fair treatment in the work environment appear to play important roles in fostering-or undermining-research integrity...
  19. pmc Males are overrepresented among life science researchers committing scientific misconduct
    Ferric C Fang
    Departments of Laboratory Medicine and Microbiology, University of Washington, School of Medicine, Seattle, Washington, USA
    MBio 4:e00640-12. 2013
    ..This exceeds the overall proportion of males among life science trainees and faculty. These observations underscore the need for additional efforts to understand scientific misconduct and to ensure the responsible conduct of research.
  20. ncbi Causal factors implicated in research misconduct: evidence from ORI case files
    Mark S Davis
    Criminal Justice Research Center, The Ohio State University, Columbus, OH 43210, USA
    Sci Eng Ethics 13:395-414. 2007
    ..The authors discuss the implications of their findings for policy and for future research...
  21. ncbi Science journal editors' views on publication ethics: results of an international survey
    E Wager
    Sideview, 19 Station Road, Princes Risborough HP27 9DE, UK
    J Med Ethics 35:348-53. 2009
    ..We surveyed journal editors to determine their views about a range of publication ethics issues...
  22. ncbi The perverse effects of competition on scientists' work and relationships
    Melissa S Anderson
    Department of Educational Policy and Administration, University of Minnesota, Minneapolis, MN 55455, USA
    Sci Eng Ethics 13:437-61. 2007
    ..When competition is pervasive, such effects may jeopardize the progress, efficiency and integrity of science...
  23. pmc Tobacco industry influence on science and scientists in Germany
    Thilo Grüning
    Department of Anaesthesia and Intensive Care, Royal Free Hospital, Royal Free Hampstead NHS Trust, London, England
    Am J Public Health 96:20-32. 2006
    ..The industry introduced serious bias that probably influenced scientific and public opinion in Germany. This influence likely undermined efforts to control tobacco use...
  24. ncbi Role of editors and journals in detecting and preventing scientific misconduct: strengths, weaknesses, opportunities, and threats
    Ana Marusic
    Croatian Medical Journal, Zagreb University School of Medicine, Croatia
    Med Law 26:545-66. 2007
    ..Journal editors cannot be the policing force of the scientific community but they should actively ensure the integrity of the scientific record...
  25. ncbi The IRB paradox: could the protectors also encourage deceit?
    Patricia Keith-Spiegel
    Department of Pyschology, Children s Hospital, Boston and Harvard Medical School, USA
    Ethics Behav 15:339-49. 2005
    ..The authors contend that, by fostering a climate in which investigators perceive that they receive fair and unbiased treatment, IRBs optimize the likelihood of collegial compliance with appropriate participant protections...
  26. pmc Investigating allegations of scientific misconduct
    Jane Smith
    BMJ 331:245-6. 2005
  27. ncbi Misconduct by researchers and authors
    Harvey Marcovitch
    BMJ Publishing Group, Committee on Publication Ethics, London, United Kingdom
    Gac Sanit 21:492-9. 2007
    ..Examples are provided of cases involving epidemiological or public health research, reported to COPE over the last 9 years. Suggestions are offered as to how misconduct might be handled in future...
  28. pmc No short-cut in assessing trial quality: a case study
    Karim F Hirji
    Department of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, P O Box 65015, Dar es Salaam, Tanzania
    Trials 10:1. 2009
    ..Using a trial of antibiotic treatment for acute otitis media, Burke et al., BMJ, 1991, as the case study, this paper illustrates some limitations of the check-list approach to trial quality assessment...
  29. pmc Self-correction in biomedical publications and the scientific impact
    Armen Yuri Gasparyan
    Armen Yuri Gasparyan, Departments of Rheumatology and Research and Development, Dudley Group NHS Foundation Trust, Russells Hall Hospital, North Block, Clinical Research Unit, Dudley, West Midlands, DY1 2HQ, United Kingdom
    Croat Med J 55:61-72. 2014
    ..To analyze mistakes and misconduct in multidisciplinary and specialized biomedical journals...
  30. pmc Investigating the previous studies of a fraudulent author
    Richard Smith
    UnitedHealth Europe, London SW1P 1SB
    BMJ 331:288-91. 2005
  31. ncbi Scientific misconduct. Even retracted papers endure
    Katherine Unger
    Science 312:40-1. 2006
  32. ncbi Commentary: the power of the unrelenting impact factor--is it a force for good or harm?
    Richard Smith
    Int J Epidemiol 35:1129-30. 2006
  33. ncbi Retracted publications in the drug literature
    Jennifer C Samp
    Center for Pharmacoeconomic Research, Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA
    Pharmacotherapy 32:586-95. 2012
    ..Articles were grouped according to reason for retraction, which was classified as scientific misconduct or error...
  34. ncbi The Scientific Misconduct Questionnaire--Revised (SMQ-R): validation and psychometric testing
    Marion E Broome
    School of Nursing, Indiana University, 1111 Middle Dr NU 132, Indianapolis, IN 46202, USA
    Account Res 12:263-80. 2005
    The overall purposes of this article are to report the development of a survey instrument, Scientific Misconduct Questionnaire-Revised (SMQ-R) that elicits the perceptions of research coordinators managing clinical trials about the ..
  35. pmc Research misconduct policies of social science journals and impact factor
    David B Resnik
    NIEHS NIH, Research Triangle Park, North Carolina 27709, USA
    Account Res 17:79-84. 2010
    ..Another important finding is that less than half of the journals that responded to the survey had a formal misconduct policy...
  36. ncbi [What can we learn from the Scott Reuben case? Scientific misconduct in anaesthesiology]
    H L Rittner
    Klinik und Poliklinik für Anästhesiologie, Zentrum Operative Medizin, Universitatsklinikum Wurzburg, 97080 Wurzburg
    Anaesthesist 58:1199-209. 2009
    In February 2009 a major case of scientific misconduct was discovered. The American pain researcher Dr. S. Reuben had published 21 papers over a period of 15 years that were found to be fraudulent...
  37. pmc What should be done to tackle ghostwriting in the medical literature?
    Peter C Gøtzsche
    Nordic Cochrane Centre, Copenhagen, Denmark
    PLoS Med 6:e23. 2009
    ..It is considered bad publication practice in the medical sciences, and some argue it is scientific misconduct. At its extreme, medical ghostwriting involves pharmaceutical companies hiring professional writers to ..
  38. ncbi Haunted manuscripts: ghost authorship in the medical literature
    Stephanie Ngai
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, M6A 2E1, Canada
    Account Res 12:103-14. 2005
    ..Other approaches have been taken by the United Kingdom and Denmark. A solution is necessary, as the relationship between authorship and accountability must be maintained...
  39. ncbi Using criminalization and due process to reduce scientific misconduct
    Benjamin K Sovacool
    Center for Science and Technology, Society Virginia Polytechnic Institute and State University, USA
    Am J Bioeth 5:W1-7. 2005
    The issue of how to best minimize scientific misconduct remains a controversial topic among bioethicists, professors, policymakers, and attorneys...
  40. pmc The persistence of error: a study of retracted articles on the Internet and in personal libraries
    Philip M Davis
    J Med Libr Assoc 100:184-9. 2012
    ..To determine the accessibility of retracted articles residing on non-publisher websites and in personal libraries...
  41. ncbi Scientific misconduct. Truth and consequences
    Jennifer Couzin
    Science 313:1222-6. 2006
  42. ncbi Scientific misconduct: a new approach to prevention
    Magne Nylenna
    Department of Public Health and General Practice, Norwegian University of Science and Technology, N 7489 Trondheim, Norway
    Lancet 367:1882-4. 2006
  43. ncbi Research misconduct policies of high impact biomedical journals
    Barbara K Redman
    Department of Medical Ethics, University of Pennsylvania, 3401 Market Street, Suite 320, Philadelphia, PA 19104 3308, USA
    Account Res 13:247-58. 2006
    ..Publicly available policies may have a deterrent effect and can prevent arbitrariness in handling cases...
  44. ncbi [Control of research ethics standards by the scientific community is not sufficient]
    Anders Persson
    Linkopings Universitet
    Lakartidningen 104:2244-7. 2007
  45. ncbi What can we learn from the Hwang and Sudbø affairs?
    Paul Gerber
    Faculty of Health Sciences, University of Queensland, Brisbane, QLD, Australia
    Med J Aust 184:632-5. 2006
    ..The present guidelines for contributors in large team investigations may need to be updated to avoid giving credit to co-authors who may have made little, if any, contribution to the work...
  46. pmc Research from tobacco industry affiliated authors: need for particular vigilance
    S Chapman
    Tob Control 14:217-9. 2005
  47. ncbi Scientific misconduct. Scandals shake Chinese science
    Hao Xin
    Science 312:1464-6. 2006
  48. ncbi New graduate students' baseline knowledge of the responsible conduct of research
    Elizabeth Heitman
    Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville Tennessee 37232, USA
    Acad Med 82:838-45. 2007
    ....
  49. ncbi Perspective: research misconduct: the search for a remedy
    Donald S Kornfeld
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Acad Med 87:877-82. 2012
    ..An increase in whistleblowing activity would provide greater, earlier exposure of misconduct and serve as a deterrent...
  50. ncbi Cooperation between research institutions and journals on research integrity cases: guidance from the Committee on Publication Ethics (COPE)
    Elizabeth Wager
    Sideview, Princes Risborough, UK
    Maturitas 72:165-9. 2012
    ....
  51. ncbi Falsified papers in high-impact journals were slow to retract and indistinguishable from nonfraudulent papers
    Nikolaos A Trikalinos
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Clin Epidemiol 61:464-70. 2008
    ..The aim was to evaluate papers retracted due to falsification in high-impact journals...
  52. ncbi Neonatal jaundice and scientific fraud in 1804
    T W R Hansen
    Department of Pediatrics, Rikshospitalet, University of Oslo, Norway
    Acta Paediatr 91:1135-8. 2002
    ..Unfortunately, university records from that period are incomplete, and it is not clear what, if anything, was done about the matter. Baumes had a very distinguished career and achieved a great reputation as both a teacher and clinician...
  53. ncbi Scientific dishonesty--questionnaire to doctoral students in Sweden
    Tore Nilstun
    Department of Medical Ethics, Lund University, Sångarevägen 4c, Lund S 224 71, Sweden
    J Med Ethics 36:315-8. 2010
    ..Participants in the research groups concerned should also be required to analyse published articles about scientific dishonesty and critically discuss what could be done about unethical conduct...
  54. pmc Research integrity in China: problems and prospects
    Weiqin Zeng
    NIEHS NIH, Box 12233 Mail Drop NH06, Research Triangle Park, North Carolina 27709, USA
    Dev World Bioeth 10:164-71. 2010
    ..Some of the challenges China faces include additional policy development, promoting education in responsible conduct of research, protecting whistle-blowers, and cultivating an ethical research environment...
  55. pmc Analysis of citations to biomedical articles affected by scientific misconduct
    Anne Victoria Neale
    Department of Family Medicine and Public Health Sciences, Wayne State University School of Medicine, 101 E Alexandrine, 249, Detroit, MI 48201, USA
    Sci Eng Ethics 16:251-61. 2010
    We describe the ongoing citations to biomedical articles affected by scientific misconduct, and characterize the papers that cite these affected articles...
  56. ncbi The university and the responsible conduct of research: who is responsible for what?
    Katherine Alfredo
    Department of Civil, Architectural and Environmental Engineering, The University of Texas, Austin, TX, USA
    Sci Eng Ethics 17:447-57. 2011
    ..This paper reflects on the rights and responsibilities of research advisers and their students and offers suggestions for clarifying both those responsibilities and the particularly murky areas of research-conduct guidelines...
  57. ncbi Teaching authorship and publication practices in the biomedical and life sciences
    Francis L Macrina
    VCU Philips Institute and Office of Research, Virginia Commonwealth University, Richmond, VA 23298 0568, USA
    Sci Eng Ethics 17:341-54. 2011
    ..These common elements provide a foundation for teaching about scientific authorship and publication practices across biomedical and life sciences disciplines...
  58. doi A tale of two citations
    Mounir Errami
    Division of Translational Research Department, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9185, USA
    Nature 451:397-9. 2008
  59. pmc Ghost authorship in industry-initiated randomised trials
    Peter C Gøtzsche
    Nordic Cochrane Centre, Copenhagen, Denmark
    PLoS Med 4:e19. 2007
    ..The prevalence and nature of ghost authorship in industry-initiated randomised trials is not known...
  60. ncbi Research misconduct, retraction, and cleansing the medical literature: lessons from the Poehlman case
    Harold C Sox
    American College of Physicians, Philadelphia, Pennsylvania 19106, USA
    Ann Intern Med 144:609-13. 2006
    ..Finally, it requires authors to take pains to avoid citing retracted articles and to issue a correction when they inadvertently cite a retracted article...
  61. pmc Tobacco industry manipulation of research
    Lisa A Bero
    Department of Clinical Pharmacy, School of Pharmacy, Institute for Health Policy Studies, University of California, San Francisco 94143, USA
    Public Health Rep 120:200-8. 2005
  62. pmc Conflicts of interest at medical journals: the influence of industry-supported randomised trials on journal impact factors and revenue - cohort study
    Andreas Lundh
    The Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark
    PLoS Med 7:e1000354. 2010
    ..We investigated industry-supported trials' influence on journal impact factors and revenue...
  63. ncbi Research misconduct and crime lessons from criminal science on preventing misconduct and promoting integrity
    Douglas Adams
    Department of Sociology and Criminal Justice, University of Arkansas, 211 Main, Fayetteville, AR 72701, USA
    Account Res 12:225-40. 2005
    ..These so-called "opportunity" theories have been shown to have practical value in reducing crime rates. We explore the promise of these newer theories for the responsible conduct of research (RCR)...
  64. ncbi The role of biostatistics in the prevention, detection and treatment of fraud in clinical trials
    M Buyse
    International Institute for Drug Development, Brussels, and Limburgs Universitair Centrum, Diepenbeek, Belgium
    Stat Med 18:3435-51. 1999
    ..Many instances of fraud in clinical trials, although morally reprehensible, have a negligible impact on the trial's scientific conclusions...
  65. pmc What have we learnt from Vioxx?
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, 333 Cedar Street, PO Box 208088, New Haven, CT 06520 8088, USA
    BMJ 334:120-3. 2007
  66. ncbi Six domains of research ethics. A heuristic framework for the responsible conduct of research
    Kenneth D Pimple
    Poynter Center for the Study of Ethics and American Institutions, Indiana University, 618 East Third Street, Bloomington, IN 47405 3602, USA
    Sci Eng Ethics 8:191-205. 2002
    ..The six domains are scientific integrity, collegiality, protection of human subjects, animal welfare, institutional integrity, and social responsibility...
  67. ncbi From authorship to contributorship. Promoting integrity in research publication
    A H White
    University of Southern Indiana, Evansville, USA
    Nurse Educ 23:26-32. 1998
    ..A method of "contributorship" is proposed which would delineate individual contributions to the research project while maintaining professional integrity, scientific accountability, and scholarly recognition...
  68. ncbi Ethical issues faced by nursing editors
    Margaret Comerford Freda
    Department of Obstetrics and Gynecology and Women s Health, Albert Einstein College of Medicine, Montefiore Medical Center
    West J Nurs Res 27:487-99. 2005
    ..Professional discussions about ethics in nursing publications should be the subject of ongoing research and scientific inquiry...
  69. ncbi Views of Iranian medical journal editors on medical research publication
    Arash Etemadi
    Endocrine Research Center and the International Journal of Endocrinology and Metabolism, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Saudi Med J 25:S29-33. 2004
    ..Medical journal editors play an important role in optimizing research publication. This study evaluates the views of Iranian medical journal editors, and their knowledge of medical publication standards...
  70. ncbi Scientific authorship. Part 1. A window into scientific fraud?
    Larry D Claxton
    Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27709, USA
    Mutat Res 589:17-30. 2005
    ..A companion paper reviews the non-fraudulent issues associated with scientific publication...
  71. ncbi Self-plagiarism: oxymoron, fair use, or scientific misconduct?
    Marion E Broome
    Nurs Outlook 52:273-4. 2004
  72. doi Integrity: Croatia's standards unusual in much of Europe
    Xavier Bosch
    Nature 454:574; author reply 575. 2008
  73. ncbi Scientific authorship. Part 2. History, recurring issues, practices, and guidelines
    Larry D Claxton
    National Health and Environmental Effects Research Laboratory, Environmental Carcinogenesis Division, U S Environmental Protection Agency, Research Triangle Park, NC 27709, USA
    Mutat Res 589:31-45. 2005
    ..Open dialogue is healthy, and it is essential for scientific integrity to be protected so that younger scientists can confidently follow the lead of their predecessors...
  74. pmc Authors, ghosts, damned lies, and statisticians
    Elizabeth Wager
    PLoS Med 4:e34. 2007
  75. ncbi Where are they now?
    Lucy Odling-Smee
    Nature 445:244-5. 2007
  76. ncbi Should journals police scientific fraud?
    Emma Marris
    Nature 439:520-1. 2006
  77. ncbi When conflict-of-interest is a factor in scientific misconduct
    Sheldon Krimsky
    Department of Urban and Environmental Policy and Planning, Tufts University, Medford, USA
    Med Law 26:447-63. 2007
    Under the guidelines adopted by the United States (U.S.) Office of Research Integrity (ORI), scientific misconduct is defined by one or more of three activities: fabrication of data, falsification of results, and plagiarism or the ..
  78. ncbi Complainant issues in research misconduct: the office of research integrity experience
    Chris B Pascal
    Office of Research Integrity, U S Department of Health and Human Services, Suite 750, Tower Building, 1101 Wootton Parkway, Rockville, MD 20852, USA
    Exp Biol Med (Maywood) 231:1264-70. 2006
    ....
  79. ncbi Scientific misconduct and research integrity for the bench scientist
    C B Pascal
    Office of Research Integrity, U S Department of Health and Human Services, Rockville, Maryland 20852, USA
    Proc Soc Exp Biol Med 224:220-30. 2000
    ..of the Office of Research Integrity (ORI), a component of the Public Health Service (PHS), in defining scientific misconduct in research supported with PHS funds and in establishing standards for responding to allegations of ..
  80. ncbi Fraud in medical research: an international survey of biostatisticians. ISCB Subcommittee on Fraud
    J Ranstam
    Malmo University, Malmo, Sweden
    Control Clin Trials 21:415-27. 2000
    ..Further research, however, is needed to assess the prevalence of different types of fraud, as well as its impact on the validity of results published in the medical literature...
  81. ncbi The Poehlman case: running away from the truth
    John E Dahlberg
    U S Department of Health and Human Services, Tower Oaks Bldg, Suite 750, Rockville, Maryland 20852, USA
    Sci Eng Ethics 12:157-73. 2006
    ..This suspicion developed into one of the most significant cases of scientific misconduct in the history of the US Department of Health and Human Services' (HHS) Office of Research Integrity (ORI),..
  82. ncbi Responding to fraud
    Donald Kennedy
    Science 314:1353. 2006
  83. ncbi Scientific misconduct. Cleaning up the paper trail
    Jennifer Couzin
    Science 312:38-43. 2006
  84. ncbi Scientific misconduct: from salami slicing to data fabrication
    Stefania M Mojon-Azzi
    Ophthalmologica 218:1-3. 2004
  85. ncbi Can authorship policies help prevent scientific misconduct? What role for scientific societies?
    Anne Hudson Jones
    Institute for the Medical Humanities, 2 210 Ashbel Smith Bldg, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1311, USA
    Sci Eng Ethics 9:243-56. 2003
    ....
  86. ncbi Multiple authors, multiple problems
    Donald Kennedy
    Science 301:733. 2003
  87. ncbi Stem cells. ...and how the problems eluded peer reviewers and editors
    Jennifer Couzin
    Science 311:23-4. 2006
  88. ncbi Plagiarize or perish?
    Tinker Ready
    Nat Med 12:494. 2006
  89. ncbi Scientific misconduct in Japan: the present paucity of oversight policy
    Brian Taylor Slingsby
    University of Tokyo Graduate School of Medicine, Japan
    Camb Q Healthc Ethics 15:294-7. 2006
  90. ncbi Seeking an international dialogue on research integrity
    Christie Aschwanden
    Cell 131:9-11. 2007
    b>Scientific misconduct is a global problem, yet protocols for addressing it remain highly fragmented and uneven...
  91. pmc A survey of newly appointed consultants' attitudes towards research fraud
    D Geggie
    Accident and Emergency Department, Arrowe Park Hospital, Arrowe Park Road, Upton, Wirral, Merseyside, CH49 5PE UK
    J Med Ethics 27:344-6. 2001
    ..To determine the prevalence of, and attitudes towards, observed and personal research misconduct among newly appointed medical consultants...
  92. ncbi Scientific misconduct. More of Bell Labs physicist's papers retracted
    Robert F Service
    Science 299:31. 2003
  93. ncbi Medical specialists and pharmaceutical industry-sponsored research: a survey of the Australian experience
    David A Henry
    School of Medical Practice and Population Health, University of Newcastle, NSW
    Med J Aust 182:557-60. 2005
    ..To characterise research relationships between medical specialists and the pharmaceutical industry in Australia...
  94. ncbi Sitting in judgement
    Erika Check
    Nature 419:332-3. 2002
  95. ncbi Authors' reports about research integrity problems in clinical trials
    William Gardner
    Department of Pediatrics and Children s Research Institute, Ohio State University, Columbus, OH, USA
    Contemp Clin Trials 26:244-51. 2005
    ..We sought to determine how frequently authors of published pharmaceutical clinical trials reported fabrication of data or misrepresentation of research...
  96. pmc Enhancing research integrity
    Vincent V Richman
    CMAJ 177:375. 2007
  97. ncbi Research ethics and lessons from Hwanggate: what can we learn from the Korean cloning fraud?
    R Saunders
    Department of Statistics, University of Oxford, Oxford, UK
    J Med Ethics 34:214-21. 2008
    ....
  98. ncbi Scientific misconduct. Researcher faces prison for fraud in NIH grant applications and papers
    Eli Kintisch
    Science 307:1851. 2005
  99. ncbi p53 tumour suppressor gene and the tobacco industry
    David H Phillips
    Lancet 365:1026; author reply 1026-7. 2005
  100. ncbi A proposal for transparency
    Drummond Rennie
    Science 298:1554; author reply 1554. 2002
  101. pmc Suspected research fraud: difficulties of getting at the truth
    Caroline White
    BMJ 331:281-8. 2005

Research Grants64

  1. Mentoring the Responsible Conduct of Research
    Celia Fisher; Fiscal Year: 2006
    ..to public health and welfare have increased heightening its public visibility especially in cases of scientific misconduct. Despite the fact that research psychologists are uniquely trained to develop psychometrically valid ..
  2. Analysis of Research Misconduct Policies: Surveys of Officers
    REBECCA LIND; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Given the ramifications of scientific misconduct, and the importance of educational/other efforts to foster the responsible conduct of research, a university's research misconduct (..
  3. Ethical Challenges for Research Extenders Responsible for the Integrity of Commun
    Celia B Fisher; Fiscal Year: 2010
    ..scientists and marginalized populations, recently the Office of Research Integrity (ORI) has uncovered scientific misconduct involving REs...
  4. Veterinary Medical Student Research Training
    LESLIE GARRY ADAMS; Fiscal Year: 2013
    ..in the Responsible Conduct of Research, emphasizing the ethical and humane use of animals in research, scientific misconduct, mentor-mentee relationships, responsible data management, conflict of interest, conflict of interest, and ..
  5. Perceived Organizational Justice and Scientific Dishone*
    GERALD KOOCHER; Fiscal Year: 2002
    Problems facing Institutional Review Boards (IRBs) and the causes and extent of scientific misconduct are described in two separate bodies of scientific literature...
  6. Human Subjects Research Enhancements Program
    Frederick Samaha; Fiscal Year: 2003
    ..The RCP will have oversight responsibilities of the Review Board, Radiation Safety Committee, Scientific Misconduct Committee, Institutional Biosafety Committee, Conflict of Interest Committee, and a Research Advocate ..
  7. A Collegial Defense Against Irresponsible Science
    GERALD KOOCHER; Fiscal Year: 2006
    Whether reports of scientific misconduct are accurate or whether publicized cases of irresponsible research represent merely the tip of the iceberg continues to be debated...
  8. Maintaining Physical Activity in Older Adult MCO Members
    Brian Martinson; Fiscal Year: 2008
    ..abstract_text> ..
  9. Work-Strain, Career Course and Research Integrity
    Brian Martinson; Fiscal Year: 2002
    ..of research integrity point to these new and unprecedented value conflicts as the driving factors in scientific misconduct. And yet, most proposals for ensuring research integrity tend to focus on "bad actors," individuals ..
  10. Procedural Justice, Identity, and Research Integrity
    Brian Martinson; Fiscal Year: 2006
    ....
  11. Research Culture of Practice-Based Research Networks
    ANNE NEALE; Fiscal Year: 2007
    ..A team of investigators from the PBRN Resource Center at Indiana University, and the Wayne State University Division of Practice-based Research will collaborate to ensure the success of the project. [unreadable] [unreadable] [unreadable]..
  12. Correcting the Literature After Scienctific Misconduct
    ANNE NEALE; Fiscal Year: 2003
    ..the nature and scope of the corrections made to the published biomedical literature affected by scientific misconduct and to make recommendations to the appropriate entities when warranted by the results of the study...
  13. New Graduate Students' Baseline Knowledge of RCR
    Elizabeth Heitman; Fiscal Year: 2003
    ..The test itself will also be readily adaptable to the evaluation of specific groups of students and others preparing for RCR instruction. ..
  14. Novel Plasmids for Porphyromonas Post-Genomic Research
    FRANCIS MACRINA; Fiscal Year: 2006
    ..Distribute these new genetic tools and knowledge about their use to workers studying Porphyromonas gingivalis and other black pigmented Gram-negative anaerobes. ..
  15. Iron Deficiency and Anemia in HIV and HCV-Infected Women
    Richard Semba; Fiscal Year: 2005
    ..S. and elsewhere. ..
  16. DNA DAMAGE AND REPAIR IN SALMONELLA PATHOGENESIS
    Ferric Fang; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  17. Genetic approach for transneuronal NA circuitry mapping
    Kwang Soo Kim; Fiscal Year: 2008
    ..Therefore, these approaches will serve as invaluable tools to elucidate the function and regulation of NA circuitry in the normal and diseased brain. [unreadable] [unreadable]..
  18. Olympus FV1000 Confocal Fluorescence Microscope
    James Goldenring; Fiscal Year: 2007
    ..Confocal fluorescence microscopy, especially in its uses for the study of living cells, holds the key to performing all of these studies. PHS 398/2590 (Rev. 09/04) [unreadable] [unreadable] [unreadable]..
  19. Modeling Research Participant Compensation
    ELIZABETH RIPLEY; Fiscal Year: 2008
    ..An R01 proposal will be submitted to further develop and test this model for feasibility, usefulness and practicality. [unreadable] [unreadable] [unreadable]..
  20. COCAINE: A STUDY OF THE BIOCHEMICAL MECHANISM OF ACTION
    Frank Carroll; Fiscal Year: 2007
    ..abstract_text> ..
  21. NOVEL PHARMACOTHERAPY FOR TREATMENT OF COCAINE ADDICTION
    Frank Carroll; Fiscal Year: 2008
    ..abstract_text> ..
  22. Iron Homeostasis in Salmonella-Host Interactions
    Ferric C Fang; Fiscal Year: 2010
    ..This work will have fundamental implications for understanding the strategies by which pathogenic microbes evade innate immunity by minimizing iron- dependent cell damage and maintaining iron homeostasis. ..
  23. Design and Development of Pharmacotherapies for Treating Stimulant Abuse
    Frank Ivy Carroll; Fiscal Year: 2010
    ..3) To continue on a limited basis our development of selected 3-phenyltropane analogs as second-generation pharmacotherapies to treat cocaine addiction. ..
  24. Community Partnership for Ethical Research
    ELIZABETH B RIPLEY; Fiscal Year: 2010
    ....
  25. Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies
    WILLIAM MARION VOLLMER; Fiscal Year: 2010
    ..This research should also be broadly applicable to other diseases and treatments. ..
  26. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  27. Developmental Stress and Vulnerability to Brain Injury
    Michael Zigmond; Fiscal Year: 2004
    ..Moreover, the methods and reagents that we develop will be made available to others in the field. ..
  28. A Qualitative Study of Editorial Decision-Making
    Lisa Bero; Fiscal Year: 2003
    ..abstract_text> ..
  29. ADAPTIVE BEHAVIOR AND BRAIN MONOAMINES
    Michael Zigmond; Fiscal Year: 2002
    ..The longer-term objectives of this project are to provide new insights into the basic neurobiology of LC neurons and the psychopathology that develops from chronic stress. ..
  30. NOVEL PHARMACOTHERAPIES FOR COCAINE DEPENDENCE
    Frank Carroll; Fiscal Year: 2001
    ..An ideal candidate compound would not only have efficacy in the preclinical models but would be safe, orally active, and potent, would not show tolerance or sensitization, and if abusable, would be less so than cocaine. ..
  31. CONSTRUCTION OF SIGNALLING FACILITY
    FRANCIS MACRINA; Fiscal Year: 2002
    ..The long-term objective of this application is to provide new infrastructure that will stimulate the development of a nationally recognized center of expertise in the field of cellular and molecular signaling. ..
  32. Management Decisions in Financial Conflicts of Interest
    Lisa Bero; Fiscal Year: 2002
    ..Our findings will allow us to develop a framework for decision-making regarding conflict identification and management. ..
  33. EFFECTS OF GENE PATENTS ON GENETIC TESTING AND RESEARCH
    Mildred Cho; Fiscal Year: 2002
    ..Our analysis will form inform public policy by indicating whether intellectual property policies or their implementation should be changed to encourage research and technology transfer, and if so, how. ..
  34. STREPTOCOCCUS SANGUIS MICROBIAL GENOME PROJECT
    FRANCIS MACRINA; Fiscal Year: 2002
    ..This, in turn, will provide researchers with new targets for vaccines and rationally designed drugs. ..
  35. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..The relationship between mastitis and breastmilk HIV load and the epidemiology and microbiology of mastitis will be examined in a new cohort of HIV-infected lactating women. ..
  36. HOSPITAL PERFORMANCE & BETA-BLOCKER USE AFTER AMI
    Harlan Krumholz; Fiscal Year: 2001
    ..abstract_text> ..
  37. GENETICS & DISABILITY INSURANCE--ETHICS, LAW & POLICY
    Jeffrey Kahn; Fiscal Year: 2001
    ....
  38. ANALYSIS OF TOBACCO DEPOSITIONS AND TRIAL TESTIMONY
    Ronald Davis; Fiscal Year: 2003
    ....
  39. Rab25 in the Pathogenesis of Ichthyosis Vulgaris
    James Goldenring; Fiscal Year: 2003
    ..In addition, it will provide the first investigations of alterations in membrane recycling in skin diseases. ..
  40. Scientific Misconduct: Role of the Research Coordinator
    Barbara Habermann; Fiscal Year: 2004
    ..a national survey of clinical research coordinators in order to describe a) their beliefs and values about scientific misconduct, b) their perceptions of factors in their institution that could influence scientific misconduct, c) their ..
  41. IMMUNOBIOLOGY OF AGING
    MARC WEKSLER; Fiscal Year: 2003
    ..The influence of anti-influenza T cell clones on the immune system of young and old mice as well as the function of the anti- influenza TCR T cell clone in young and old mice will be studied. ..
  42. Effectiveness of RCR Instruction
    FRANCIS MACRINA; Fiscal Year: 2003
    ..Although our study focuses solely on authorship and publication practices, we expect our approach will set the stage for parallel studies in other core topic areas. ..
  43. Hepcidin and the pathogenesis of anemia in older adults.
    Richard D Semba; Fiscal Year: 2010
    ..This study should provide new insight into the epidemiology and biological mechanisms of anemia among older adults and help identify strategies aimed at the prevention and treatment of anemia. ..
  44. Oxidative Stress and the Pathogenesis of Sarcopenia and Disability in Older Women
    Richard Semba; Fiscal Year: 2008
    ..AGEs are a potentially modifiable risk factor, as circulating AGEs can be lowered by dietary modification and by pharmacological intervention. ..
  45. VITAMIN A SUPPLEMENTATION FOR HIV INFECTED CHILDREN
    Richard Semba; Fiscal Year: 2002
    ....
  46. Research Ethics Course for Research Nurse Coordinators
    ANN HAMRIC; Fiscal Year: 2004
    ..abstract_text> ..
  47. B Cell Repertoire and B cell Neoplasms in Old Mice
    MARC WEKSLER; Fiscal Year: 2006
    ..abstract_text> ..
  48. Telemonitoring to improve heart failure outcomes
    Harlan Krumholz; Fiscal Year: 2008
    ..abstract_text> ..
  49. A Program for Expanding ELSI Undergraduate Pedagogy
    Ronald Green; Fiscal Year: 2005
    ..This proposal represents a logical next step in the employment of the skills and resources we have developed at Dartmouth for undergraduate ELSI education. ..
  50. TRAINING FACULTY TO TEACH SURVIVAL SKILLS AND ETHICS
    Michael Zigmond; Fiscal Year: 2005
    ..Efforts will be made to promote diversity with regard to the demographics of both the workshop participants and those they serve. Instruction will be provided by the PI's together with a highly qualified group of trainers. ..
  51. Development Stress, Exercise, and Vulnerability to Neuronal Injury
    Michael J Zigmond; Fiscal Year: 2010
    ....
  52. Osteopontin regulates ubiquitin-proteasome degradation of STAT1
    Paul Kuo; Fiscal Year: 2008
    ..Characterization of this regulatory pathway may identify potential regulatory targets for therapy in septic shock. ..
  53. GENETICS OF A NEWLY EVOLVED TESTES SPECIFIC GENE SDIC
    Daniel Hartl; Fiscal Year: 2003
    ..Aim 5 recognizes Sdic as a candidate gene with a possible role in postmating reproductive isolation between D. melanogaster and D. simulans, which will be tested by interspecific germline transformation. ..
  54. GENOME EVOLUTION AND THE INSERTION/DELETION SPECTRUM
    Daniel Hartl; Fiscal Year: 2002
    ..Analysis of the limited data presently available for these pseudogenes yields inconclusive, and possibly inconsistent, results. ..
  55. Strategies to reduce time to reperfusion therapy for MI
    Harlan Krumholz; Fiscal Year: 2005
    ..Data generated from these studies will guide efforts by clinicians, administrators, researchers, and policy makers to decrease time to reperfusion therapy for patients with STEMI. ..
  56. Evolutionary Genomics of Drosophila
    Daniel Hartl; Fiscal Year: 2007
    ..abstract_text> ..
  57. Culture of differentiated C elegans embryonic cells
    Kevin Strange; Fiscal Year: 2002
    ..The speed and economy with which this can be done in C. elegans cannot be duplicated in other metazoan animals. ..
  58. Use of Automated Phone Calls to Promote Adherence with Inhaled Corticosteroids
    William Vollmer; Fiscal Year: 2009
    ..This method, if it helps people take their medications as prescribed, could be used with a variety of other long-term medical conditions. ..
  59. American Association for Cancer Education Annual Meeting
    ARTHUR MICHALEK; Fiscal Year: 2005
    ..It presents an opportunity to network and pilot innovative approaches in cancer education. ..
  60. Genetic analysis of C. elegans cellular ormoregulation
    Kevin Strange; Fiscal Year: 2004
    ..elegans will likely provide unique insights into osmoregulation, signaling mechanisms, and cellular stress and damage repair )rocesses in kidney cells as well as other mammalian cell types and tissues. ..
  61. Hepatocyte iNOS expression is redox-regulated by HNF-4
    Paul Kuo; Fiscal Year: 2007
    ..Our studies will define a novel and, as yet, poorly described redox-dependent signal transduction pathway which regulates iNOS as an antioxidant mechanism in hepatocytes. [unreadable] [unreadable]..
  62. Redox-mediated p300 regulation of hepatocyte NF-kB
    Paul Kuo; Fiscal Year: 2007
    ..Given the novel and high risk nature of this experimental venture, we believe the R21 funding mechanism to be particularly relevant. [unreadable] [unreadable] [unreadable]..
  63. ENTERIC PHYSIOLOGY OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 2007
    ..This proposal will define important, novel neural mechanisms regulating motor and absorptive function in the denervated gut. Selected aspects have translational value to clinical gut transplantation. [unreadable] [unreadable]..
  64. Responsible Record Keeping Practices: Standards & Practices of Funded Researchers
    Kenneth Wilson; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..