conflict of interest
Summary: A situation in which an individual might benefit personally from official or professional actions. It includes a conflict between a person's private interests and official responsibilities in a position of trust. The term is not restricted to government officials. The concept refers both to actual conflict of interest and the appearance or perception of conflict.
Publications304 found, 100 shown here
- Scope and impact of financial conflicts of interest in biomedical research: a systematic reviewJustin E Bekelman
Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
JAMA 289:454-65. 2003..Despite increasing awareness about the potential impact of financial conflicts of interest on biomedical research, no comprehensive synthesis of the body of evidence relating to financial conflicts of interest has been performed...
- Physicians and the pharmaceutical industry: is a gift ever just a gift?A Wazana
McGill University, Montreal, Quebec, Canada
JAMA 283:373-80. 2000....
- Conflict of interest: use of pyrethroids and amidines against tsetse and ticks in zoonotic sleeping sickness endemic areas of UgandaKevin Bardosh
Division of Pathway Medicine and Centre for Infectious Diseases, School of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
Parasit Vectors 6:204. 2013..This study explored insecticide sales, demand and use in four districts of Uganda where mass cattle treatments have been undertaken by the 'Stamp Out Sleeping Sickness' programme...
- Prevalence of financial conflicts of interest among panel members producing clinical practice guidelines in Canada and United States: cross sectional studyJennifer Neuman
Department of Preventive Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1057, New York, NY 10029, USA
BMJ 343:d5621. 2011..To determine the prevalence of financial conflicts of interest among members of panels producing clinical practice guidelines on screening, treatment, or both for hyperlipidaemia or diabetes...
- Physician professionalism and changes in physician-industry relationships from 2004 to 2009Eric G Campbell
Mongan Institute for Health Policy, Massachusetts General Hospital, 50 Staniford St, Ninth Floor, Boston, MA 02114, USA
Arch Intern Med 170:1820-6. 2010..Since 2004 much has been done at the institutional, state, and national levels to limit PIRs. This study estimates the nature, extent, consequences, and changes in PIRs nationally...
- Factors associated with findings of published trials of drug-drug comparisons: why some statins appear more efficacious than othersLisa Bero
Clinical Pharmacy and Health Policy, University of California, San Francisco, California, United States of America
PLoS Med 4:e184. 2007....
- A social science perspective on gifts to physicians from industryJason Dana
Department of Social and Decision Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA
JAMA 290:252-5. 2003
- Requirements and definitions in conflict of interest policies of medical journalsJared A Blum
Brown University College of Medicine, Providence, Rhode Island, USA
JAMA 302:2230-4. 2009..Conflicts of interest (COIs) may influence medical literature. However, it is unclear whether medical journals have consistent policies for defining and soliciting COI disclosures...
- Conflict of interest in clinical practice guideline development: a systematic reviewSusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon, United States of America
PLoS ONE 6:e25153. 2011..We performed a systematic review of the prevalence of COI and its effect on CPG recommendations...
- Bias in published cost effectiveness studies: systematic reviewChaim M Bell
St Michael s Hospital, Toronto, Ontario, Canada M5B 1W8
BMJ 332:699-703. 2006....
- Conflicts of interest at medical journals: the influence of industry-supported randomised trials on journal impact factors and revenue - cohort studyAndreas Lundh
The Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark
PLoS Med 7:e1000354. 2010transparency in reporting of conflict of interest is an increasingly important aspect of publication in medical journals...
- Accuracy of conflict-of-interest disclosures reported by physiciansKanu Okike
Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
N Engl J Med 361:1466-74. 2009..The recent public reporting of payments made to physicians by manufacturers of orthopedic devices provides an opportunity to assess the accuracy of physicians' conflict-of-interest disclosures...
- The perils of ignoring history: Big Tobacco played dirty and millions died. How similar is Big Food?Kelly D Brownell
Rudd Center for Food Policy andObesity, Yale University, 309 Edwards Street, New Haven, CT06520 8369, USA
Milbank Q 87:259-94. 2009..In the hope that the food history will be written differently, this article both highlights important lessons that can be learned from the tobacco experience and recommends actions for the food industry...
- Author's specialty and conflicts of interest contribute to conflicting guidelines for screening mammographySusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR 97239, USA
J Clin Epidemiol 65:725-33. 2012..To examine the relationship between guideline panel members' conflicts of interest and guideline recommendations on screening mammography in asymptomatic, average-risk women aged 40-49 years...
- Conflict of interest disclosures for clinical practice guidelines in the national guideline clearinghouseSusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon, United States of America
PLoS ONE 7:e47343. 2012b>Conflict of interest (COI) is an important potential source of bias in the development of clinical practice guidelines (CPGs) and high rates of COI among guideline authors have been reported in the past...
- Responses of medical schools to institutional conflicts of interestSusan H Ehringhaus
Association of American Medical Colleges, Washington, DC 20037, USA
JAMA 299:665-71. 2008..Institutional financial conflicts of interest may affect research results. No national data exist on the extent to which US medical schools have formally responded to challenges associated with institutional conflicts of interest (ICOI)...
- How pharmaceutical industry funding affects trial outcomes: causal structures and responsesSergio Sismondo
Queen s University, Philosophy, John Watson Hall, Kingston, Canada
Soc Sci Med 66:1909-14. 2008..Given these points, most proposed measures to respond to this bias are too piecemeal to be adequate...
- Nonfinancial conflicts of interest in researchNorman G Levinsky
Boston University Medical Center, Boston, MA 02118, USA
N Engl J Med 347:759-61. 2002
- Association between industry affiliation and position on cardiovascular risk with rosiglitazone: cross sectional systematic reviewAmy T Wang
Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
BMJ 340:c1344. 2010..To explore a possible link between authors' financial conflicts of interest and their position on the association of rosiglitazone with increased risk of myocardial infarction in patients with diabetes...
- From disclosure to transparency: the use of company payment dataSusan Chimonas
Center on Medicine as a Profession, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Arch Intern Med 171:81-6. 2011..However, these requirements vary among journals and often lack specificity. As a result, disclosures may not consistently reveal author-industry ties...
- Do pressures to publish increase scientists' bias? An empirical support from US States DataDaniele Fanelli
INNOGEN and Institute for the Study of Science, Technology and Innovation, The University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e10271. 2010..The same phenomenon might be observed in other countries where academic competition and pressures to publish are high...
- The vexing problem of guidelines and conflict of interest: a potential solutionGordon Guyatt
McMaster University Health Sciences Centre, Henderson General Hospital, Hamilton, Ontario, Canada
Ann Intern Med 152:738-41. 2010Issues of financial and intellectual conflict of interest in clinical practice guidelines have raised increasing concern. Professional organizations have responded by more rigorous regulation of conflict of interest...
- Reporting of conflicts of interest in meta-analyses of trials of pharmacological treatmentsMichelle Roseman
Department of Psychiatry, McGill University, Montreal, Quebec, Canada
JAMA 305:1008-17. 2011..Authors of meta-analyses, however, are not required to report COIs disclosed in original reports of included RCTs...
- The development of clinical practice guidelines and guidance statements of the American College of Physicians: summary of methodsAmir Qaseem
American College of Physicians, Philadelphia, Pennsylvania 19106, USA
Ann Intern Med 153:194-9. 2010..All ACP clinical practice guidelines and clinical guidance statements, if not updated, are considered automatically withdrawn or invalid 5 years after publication or once an update has been issued...
- Level of evidence and conflict of interest disclosure associated with higher citation rates in orthopedicsKanu Okike
Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
J Clin Epidemiol 64:331-8. 2011..To identify the scientific and nonscientific factors associated with rates of citation in the orthopedic literature...
- Doctors and drug companies--scrutinizing influential relationshipsEric G Campbell
Massachusetts General Hospital and Harvard Medical School, Boston, USA
N Engl J Med 357:1796-7. 2007
- Medical merchants: conflict of interest, office product sales and notifiable conductMalcolm H Parker
School of Medicine, University of Queensland, Brisbane, QLD, Australia
Med J Aust 194:34-7. 2011Professional ethical codes identify the issue of conflict of interest, which can distort doctors' objective judgements concerning the best interests of patients...
- Conflict of interest and FCTC implementation in ChinaXia Wan
Department of Epidemiology and Statistics, Institute of Basic Medical Sciences of Chinese Academy of Medical Sciences, School of Basic Medicine of Peking Union Medical College, Beijing, China
Tob Control 21:412-5. 2012..To critically review the structure of tobacco control policy making in China, examine conflicts of interest within this structure, and consider how these affected the introduction of on-pack warnings...
- Disclosing conflicts of interest in German publications concerning health services researchNils Schneider
Department of Epidemiology, Social Medicine and Health System Research, Hannover Medical School, Hannover, Germany
BMC Health Serv Res 7:78. 2007..The objective of this work is to examine the disclosure practice of financial and non-financial conflicts of interest in German language publications concerning health services research for the first time...
- Conflict of interest guidelines for clinical guidelinesMichael J Williams
School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic
Med J Aust 195:442-5. 2011..on the National Health and Medical Research Council portal from the most prolific developers have published conflict of interest statements, and fewer detail the processes used to manage conflicts...
- Prescribers and pharmaceutical representatives: why are we still meeting?Melissa A Fischer
University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
J Gen Intern Med 24:795-801. 2009..This work has primarily been with physicians and physician-trainees. Questions remain regarding why prescribers continue to meet with pharmaceutical representatives (PRs)...
- Conflict of interest in economic analyses of aromatase inhibitors in breast cancer: a systematic reviewSekwon Jang
Division of Hematology, Oncology and Transplantation, University of Minnesota, 14 142 PWB, 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455, USA
Breast Cancer Res Treat 121:273-9. 2010..Economic evaluations of aromatase inhibitors in breast cancer that are funded by a pharmaceutical company are less likely to reach unfavorable conclusions about the sponsor's product...
- Tobacco industry sponsorship of a book and conflict of interestMi Kyung Hong
Department of Clinical Pharmacy and Center for Tobacco Control Research and Education, University of California, San Francisco, CA, USA
Addiction 101:1202-11. 2006..The objective of this study is to examine tobacco industry involvement in the development of scientific books...
- Does exposure to conflict of interest policies in psychiatry residency affect antidepressant prescribing?Andrew J Epstein
Department of Veterans Affairs Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA
Med Care 51:199-203. 2013Academic medical institutions have instituted conflict of interest (COI) policies in response to concerns about pharmaceutical industry influence.
- Ethical assessment of industry-sponsored clinical trials: a case analysisFranklin G Miller
Department of Clinical Bioethics, National Institutes of Health, Bethesda, MD 20892 1156, USA
Chest 121:1337-42. 2002....
- Frequency, nature, effects, and correlates of conflicts of interest in published clinical cancer researchReshma Jagsi
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 5010, USA
Cancer 115:2783-91. 2009..Relationships between clinical researchers and industry are becoming increasingly complex. The frequency and impact of conflicts of interest in the full range of high-impact, published clinical cancer research is unknown...
- Conflict-of-interest policies for investigators in clinical trialsB Lo
Medical Ethics, Center for AIDS Prevention Studies, University of California at San Francisco, USA
N Engl J Med 343:1616-20. 2000..There is substantial concern that financial conflicts of interest on the part of investigators conducting clinical trials may compromise the well-being of research subjects...
- Quantifying the variability of financial disclosure information reported by authors presenting at annual spine conferencesBrian L Ju
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT 06520 8071, USA
Spine J 11:1-8. 2011..However, the consistency of such reporting among spine surgeons remains unknown. This study quantifies the variability in the self-reported disclosures of individual authors presenting at multiple spine conferences during the same year...
- The impact of disclosing financial ties in research and clinical care: a systematic reviewAdam Licurse
Section of General Internal Medicine, Yale School of Medicine, PO Box 208025, New Haven, CT 06520 8025, USA
Arch Intern Med 170:675-82. 2010..Despite increased demand for disclosure of physician and researcher financial ties (FTs) to industry, little is known about patients', research participants', or journal readers' attitudes toward FTs...
- The role of conflict of interest in reporting of scientific informationRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 136:253-9. 2009..Therefore, this commentary has been written to review what we know about the role of conflict of interest (COI) in the reporting of scientific information and to challenge those of us in educator roles to do a ..
- Managing conflicts of interest in the conduct of clinical trialsKarine Morin
Council on Ethical and Judicial Affairs, Ethics Standards Group, American Medical Association, 515 N State St, Chicago, IL 60610, USA
JAMA 287:78-84. 2002..Finally, the article addresses disclosure of financial incentives and related funding issues...
- Final report of the Lyme disease review panel of the Infectious Diseases Society of AmericaPaul M Lantos
Duke University Medical Center, Durham, North Carolina 27710, USA
Clin Infect Dis 51:1-5. 2010....
- An official American Thoracic Society Policy statement: managing conflict of interest in professional societiesHolger J Schunemann
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Am J Respir Crit Care Med 180:564-80. 2009Competing interests occur frequently in health care. This results in the potential for conflict of interest (COI). COI can lead to biased generation or assessment of evidence and misinform healthcare decision makers...
- Study of neurontin: titrate to effect, profile of safety (STEPS) trial: a narrative account of a gabapentin seeding trialSamuel D Krumholz
Never Again Consulting LLC, Providence, Rhode Island, USA
Arch Intern Med 171:1100-7. 2011..Seeding trials, clinical studies conducted by pharmaceutical companies for marketing purposes, have rarely been described in detail...
- Partisan perspectives in the medical literature: a study of high frequency editorialists favoring hormone replacement therapyAthina Tatsioni
Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina 45110, Greece
J Gen Intern Med 25:914-9. 2010..Unfavorable results of major studies have led to a large shrinkage of the market for hormone replacement therapy (HRT) in the last 6 years. Some scientists continue to strongly support the use of HRT...
- Invited Article: Conflicts of interest for authors of American Academy of Neurology clinical practice guidelinesR G Holloway
Department of Neurology, University of Rochester, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
Neurology 71:57-63. 2008..Clinical practice guidelines (CPGs) shape clinical care worldwide but are prone to potential error and bias due to conflicts of interest (COI)...
- Financial conflicts of interest in physicians' relationships with the pharmaceutical industry--self-regulation in the shadow of federal prosecutionDavid M Studdert
Harvard School of Public Health, Boston, USA
N Engl J Med 351:1891-900. 2004
- Financial and intellectual conflicts of interest: confusion and clarityJulian Bion
Department of Intensive Care Medicine, University of Birmingham, Birmingham, UK
Curr Opin Crit Care 15:583-90. 2009..To examine the literature on competing interests for individuals and organizations involved in healthcare and to determine the nature and extent of the problem, and the most effective methods of management...
- Conflicts of interest in cardiovascular clinical practice guidelinesTodd B Mendelson
School of Medicine, Center for Bioethics, University of Pennsylvania, Philadelphia, PA 19104, USA
Arch Intern Med 171:577-84. 2011..The extent of conflicts of interest (COIs) in cardiology guideline production has not been well studied. Herein, we describe the scope of COIs in CPGs...
- Extent and impact of industry sponsorship conflicts of interest in dermatology researchClifford S Perlis
Department of Dermatology, Rhode Island Hospital and Brown Medical School, Providence, Rhode Island, USA
J Am Acad Dermatol 52:967-71. 2005..Despite this evolving discussion in the general medical literature, little is known about the extent or role of financial conflicts of interest in dermatology research...
- The ADVANTAGE seeding trial: a review of internal documentsKevin P Hill
McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Ann Intern Med 149:251-8. 2008..Seeding trials, clinical studies conducted by pharmaceutical companies that are designed to seem as if they answer a scientific question but primarily fulfill marketing objectives, have not been described in detail...
- Consistency of financial interest disclosures in the biomedical literature: the case of coronary stentsKevin P Weinfurt
Duke Clinical Research Institute, Duke Translational Medicine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America
PLoS ONE 3:e2128. 2008..We examined whether authors' financial interests were disclosed consistently in articles on coronary stents published in 2006...
- The effect of conflict of interest on biomedical research and clinical practice guidelines: can we trust the evidence in evidence-based medicine?John Abramson
Ambulatory Care and Prevention, Harvard Medical School, Cambridge, MA, USA
J Am Board Fam Pract 18:414-8. 2005
- Tobacco industry influence on science and scientists in GermanyThilo Grüning
Department of Anaesthesia and Intensive Care, Royal Free Hospital, Royal Free Hampstead NHS Trust, London, England
Am J Public Health 96:20-32. 2006..The industry introduced serious bias that probably influenced scientific and public opinion in Germany. This influence likely undermined efforts to control tobacco use...
- Association between competing interests and authors' conclusions: epidemiological study of randomised clinical trials published in the BMJLise L Kjaergard
Cochrane Hepatobiliary Group, Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital, Department 7102, H S Rigshospitalet, DK 2100 Copenhagen, Denmark
BMJ 325:249. 2002..To assess the association between competing interests and authors' conclusions in randomised clinical trials...
- Reporting of conflicts of interest in guidelines of preventive and therapeutic interventionsG N Papanikolaou
Clinical Trials and Evidence Based Medicine Unit, and Social Medicine and Public Health Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina 45110, Greece
BMC Med Res Methodol 1:3. 2001....
- Early Toronto experience with new standards for industry-sponsored clinical research: a progress reportC David Naylor
Faculty of Medicine, University of Toronto, Ont
CMAJ 166:453-6. 2002
- Managing conflicts of interest in clinical care: a national survey of policies at U.S. medical schoolsSusan Chimonas
Center on Medicine as a Profession, Columbia University, New York, New York 10032, USA
Acad Med 86:293-9. 2011..However, no reliable data exist on the extent to which schools have policies to manage CCOIs. The authors sought to determine the extent and strength of medical schools' CCOI policies...
- Task force 1: The ACCF and AHA codes of conduct in human subjects researchJoseph S Alpert
J Am Coll Cardiol 44:1724-8. 2004
- Scientific and legal perspectives on science generated for regulatory activitiesCarol J Henry
American Chemistry Council, Arlington, Virginia, USA
Environ Health Perspect 116:136-41. 2008..In a closely related example, the U.S. Environmental Protection Agency considered but abandoned a program to implement standards aimed at "external" information...
- Financial ties between DSM-IV panel members and the pharmaceutical industryLisa Cosgrove
University of Massachusetts, Boston, USA
Psychother Psychosom 75:154-60. 2006..The authors examined the degree and type of financial ties to the pharmaceutical industry of panel members responsible for revisions of the Diagnostic and Statistical Manual of Mental Disorders(DSM)...
- Do doctors rely on pharmaceutical industry funding to attend conferences and do they perceive that this creates a bias in their drug selection? Results from a questionnaire surveyPhilip Rutledge
Lothian Primary Care Trust, Edinburgh, Scotland, UK
Pharmacoepidemiol Drug Saf 12:663-7. 2003To determine the sources of funding for doctors attending conferences and meetings and the doctors' perception on whether their involvement with the pharmaceutical industry created a conflict of interest or bias in their drug selection.
- Influence of drug company authorship and sponsorship on drug trial outcomesTongeji Tungaraza
North East Wales Trust, UK
Br J Psychiatry 191:82-3. 2007..Independent studies were more likely to report negative findings than industry-funded studies. However, the involvement of a drug company employee had a much greater effect on study outcome than financial sponsorship alone...
- Keeping science on top in drug evaluationJerry Avorn
Harvard Medical School and Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women s Hospital, Boston, USA
N Engl J Med 357:633-5. 2007
- Poor reporting of search strategy and conflict of interest in over 250 narrative and systematic reviews of two biologic agents in arthritis: a systematic reviewAimee Kendall Roundtree
The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Epidemiol 62:128-37. 2009..To evaluate the quality of reviews about etanercept (ETN) and infliximab (IFX), two biologic treatments for rheumatoid arthritis (RA)...
- Assessing whether to receive funding support from tobacco, alcohol, gambling and other dangerous consumption industriesPeter J Adams
School of Population Health, University of Auckland, Auckland, New Zealand
Addiction 102:1027-33. 2007..To examine the risks taken by health, research and community organizations when they opt to receive funding from dangerous consumption industries and to identify ways in which they might generate their own assessment of these risks...
- Current levels of conflict of interest disclosure in medical publications from KoreaBo Hyoung Kang
Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Seoul, Korea
J Korean Med Sci 28:978-82. 2013..The aims of this study were to determine the prevalence of author-related conflict of interest (COI) policies and evaluate the actual state of COI disclosure in Korean medical journals...
- ACCP evidence-based guideline development: a successful and transparent approach addressing conflict of interest, funding, and patient-centered recommendationsMichael H Baumann
University of Mississippi Medical Center, Jackson, MS, USA
Chest 132:1015-24. 2007..A review of this process is provided to inform the ACCP membership and those wishing to embark on EBG development...
- The tobacco industry and pesticide regulations: case studies from tobacco industry archivesPatricia A McDaniel
Center for Tobacco Control Research and Education, University of California, San Francisco, California 94143 1390, USA
Environ Health Perspect 113:1659-65. 2005....
- Haunted manuscripts: ghost authorship in the medical literatureStephanie Ngai
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, M6A 2E1, Canada
Account Res 12:103-14. 2005..Other approaches have been taken by the United Kingdom and Denmark. A solution is necessary, as the relationship between authorship and accountability must be maintained...
- The Philip Morris External Research Program: results from the first round of projectsN Hirschhorn
Tob Control 15:267-9. 2006..We concluded that a prime reason for PMERP's existence was to garner scientific credibility for PM...
- Gifts to physicians from the pharmaceutical industry: an ethical analysisCatherine A Marco
Department of Emergency Medicine, St Vincent Mercy Medical Center, Toledo, OH 43608 2691, USA
Ann Emerg Med 48:513-21. 2006..We conclude with a list of summary recommendations designed to help individual physicians, educators, and administrators engage in careful reflection and analysis and make sound ethical decisions about acceptance of gifts...
- Conflict of interest in clinical practiceMark R Tonelli
University of Washington, Seattle, WA 98195 6522, USA
Chest 132:664-70. 2007..Recognition and acknowledgment are the first steps in ameliorating conflicts of interest, which can then be disclosed and potentially eliminated...
- Conflicts of interest among authors of clinical practice guidelines for glycemic control in type 2 diabetes mellitusSusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon, United States of America
PLoS ONE 8:e75284. 2013b>Conflict of interest (COI) is an important potential source of bias in the development of clinical practice guidelines (CPGs).
- Quantitative analysis of sponsorship bias in economic studies of antidepressantsC Bruce Baker
Department of Psychiatry, Yale School of Medicine, and Connecticut Mental Health Center, New Haven, Connecticut 06519, USA
Br J Psychiatry 183:498-506. 2003..Concern is widespread about potential sponsorship influence on research, especially in pharmacoeconomic studies. Quantitative analysis of possible bias in such studies is limited...
- Reporting of conflicts of interest from drug trials in Cochrane reviews: cross sectional studyMichelle Roseman
Lady Davis Institute for Medical Research, Jewish General Hospital and McGill University, Montreal, Quebec, Canada, H3T 1E4
BMJ 345:e5155. 2012..To investigate the degree to which Cochrane reviews of drug interventions published in 2010 reported conflicts of interest from included trials and, among reviews that reported this information, where it was located in the review documents...
- Author disclosure of conflict of interest in vascular surgery journalsThomas L Forbes
Division of Vascular Surgery, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada
J Vasc Surg 54:55S-8S. 2011..This study reviewed conflict of interest (COI) disclosure in the vascular surgery journals regarding several selected technology-driven topics, ..
- A statement by the editors of The LancetRichard Horton
The Lancet, 32 Jamestown Road, London NW1 7BY, UK
Lancet 363:820-1. 2004
- Editors' declaration of their own conflicts of interestIrina Haivas
BMJ Editorial Office, BMA House, Tavistock Square, London, UK
CMAJ 171:475-6. 2004
- Research misconduct policies of scientific journalsDavid B Resnik
National Institute of Environmental Health Sciences NIEHS, National Institutes of Health NIH, Research Triangle Park, North Carolina 27709, USA
Account Res 16:254-67. 2009..88). Our research indicates that more than half of scientific journals have developed misconduct policies, but that most of these policies do not define research misconduct and most of these policies were not generated by the journal...
- Nurse practitioners' perceptions and participation in pharmaceutical marketingNancy Crigger
William Jewell College, Liberty, Missouri, USA
J Adv Nurs 65:525-33. 2009..This paper reports on a study conducted to describe family nurse practitioners' perceptions towards and participation in pharmaceutical marketing and to explore the relationships among related variables...
- "Under the radar": nurse practitioner prescribers and pharmaceutical industry promotionsElissa C Ladd
Institute of Health Professions School of Nursing, 36 First Ave, Boston, MA 02129, USA
Am J Manag Care 16:e358-62. 2010..To assess nurse practitioners' interactions with pharmaceutical industry promotional activities and their perception of information reliability and self-reported prescribing behaviors...
- Conflicts of interest in medical science: peer usage, peer review and 'CoI consultancy'Bruce G Charlton
Med Hypotheses 63:181-6. 2004..b>Conflict of interest (CoI) declarations have traditionally been considered inappropriate in pure science since its evaluation ..
- Conflicts of interest: a review of institutional policy in Australian medical schoolsPaul R Mason
Royal Melbourne Hospital, Melbourne, Vic, Australia
Med J Aust 194:121-5. 2011..To examine the adequacy of policies at Australian medical schools for managing potential conflicts of interest with the pharmaceutical industry...
- Financial payments by orthopedic device makers to orthopedic surgeonsJason M Hockenberry
Department of Health Policy and Management, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA 30322, USA
Arch Intern Med 171:1759-65. 2011There is ongoing concern over potential conflict of interest inherent in physician relationships with industry. However, there are limited empirical data detailing the prevalence and magnitude of these relationships...
- Are self-regulation and declaration of conflict of interest still the benchmark for relationships between physicians and industry?Ian E Haines
Melbourne Oncology Group, Cabrini Health, Melbourne, Vic, Australia
Med J Aust 189:263-6. 2008..literature reviews and treatment guidelines have been associated with widespread declarations of conflict of interest. Some potential solutions are: regulating pharmaceutical companies to declare all gifts to clinicians, or ..
- Conflict of interest policies and disclosure requirements among European Society of Cardiology National Cardiovascular JournalsFernando Alfonso
Interventional Cardiology, Cardiovascular Institute, Clinico San Carlos University Hospital, Plaza de Cristo Rey, Cuidad Universitaria, Madrid, Spain
Rev Port Cardiol 31:329-36. 2012..b>Conflict of interest disclosure, however, is not systematically nor consistently dealt with by journals...
- Disclosure of industry payments to physiciansRobert Steinbrook
N Engl J Med 359:559-61. 2008
- Prevalence and reliability of self-reported authorship disclosures in Otolaryngology-Head and Neck SurgeryNeil Bhattacharyya
Division of Otolaryngology Head and Neck Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
Otolaryngol Head Neck Surg 141:311-5. 2009..Determine reliability of self-reported authorship disclosures of potential conflicts of interest in American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF)-sponsored presentations and publications...
- Task force 3: Disclosure of relationships with commercial interests: policy for educational activities and publicationsAlice K Jacobs
J Am Coll Cardiol 44:1736-40. 2004
- Promotional tone in reviews of menopausal hormone therapy after the Women's Health Initiative: an analysis of published articlesAdriane Fugh-Berman
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC, USA
PLoS Med 8:e1000425. 2011....
- Characteristics of physicians receiving large payments from pharmaceutical companies and the accuracy of their disclosures in publications: an observational studySusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Mail Code BICC, Portland, OR 97239, USA
BMC Med Ethics 13:24. 2012..Our objectives were to describe physician recipients of large total payments from these seven companies, and to examine discrepancies between these payments and conflict of interest (COI) disclosures in authors' concurrent publications.
- Policies on faculty conflicts of interest at US universitiesM K Cho
Stanford University Center for Biomedical Ethics, 701 Welch Rd, Suite 1105, Palo Alto, CA 94304, USA
JAMA 284:2203-8. 2000..Public scrutiny of these ties is increasing, especially in cases where researchers have financial interests in the corporate sponsors of their clinical research...
- Conflicts of interest and disclosure in the American Psychiatric Association's Clinical Practice GuidelinesLisa Cosgrove
Department of Counseling and School Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Psychother Psychosom 78:228-32. 2009..The present study examined the degree and type of financial ties to the pharmaceutical industry held by authors of 3 major CPG...
- Perceptions of conflict of interest disclosures among peer reviewersSuzanne Lippert
Department of Emergency Medicine, Alameda County Medical Center, Oakland, California, United States of America
PLoS ONE 6:e26900. 2011..We investigate reviewers' perceptions of potential bias introduced by particular author disclosures, and whether reviewer characteristics are associated with a greater likelihood of perceiving bias...
- Conflict of interest in oncology publications: a survey of disclosure policies and statementsAaron S Kesselheim
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Cancer 118:188-95. 2012..The authors sought to define current disclosure policies and how they relate to disclosure statements provided by authors in major oncology journals...
- Conflict of interest policies for organizations producing a large number of clinical practice guidelinesSusan L Norris
Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon, United States of America
PLoS ONE 7:e37413. 2012b>Conflict of interest (COI) of clinical practice guideline (CPG) sponsors and authors is an important potential source of bias in CPG development...
- Vinyl chloride: a case study of data suppression and misrepresentationJennifer Beth Sass
Natural Resources Defense Council, Washington, DC 20005, USA
Environ Health Perspect 113:809-12. 2005..S. EPA reverse its trend toward ever-increasing collaborations with the regulated industries when generating scientific reviews and risk assessments...
- Disclosure of competing financial interests and role of sponsors in phase III cancer trialsJean Jacques Tuech
Laboratoire d Ethique Médicale et Médecine Légale, Faculté de médecine de Paris 5, 45 Rue des Saints Peres, 75006 Paris, France
Eur J Cancer 41:2237-40. 2005..In the meantime, researchers do well to arm themselves with the rules for research partnerships and editors to take on the role of watchdog...
- Conflict of interest or contravention of science?Christopher J Borgert
President and Principal Scientist, Applied Pharmacology and Toxicology, Inc, 2250 NW 24th Avenue, Gainesville, FL 32605, USA
Regul Toxicol Pharmacol 48:4-5. 2007Invasive conflict of interest disclosures are now normative requirements for participation in the operations of science, pursuant to a sea of ink intended ostensibly to advocate for objectivity...
- Research funding, conflicts of interest, and the meta-methodology of public relationsSheldon Rampton
Center for Media and Democracy, Madison, WI 53703, USA
Public Health Rep 117:331-9. 2002
- Surrogate Consent in ResearchMichelle Ng Gong; Fiscal Year: 2010..vulnerable themselves or in studies involving genetic testing where the surrogates may have a potential conflict of interest. The broad objective of this proposal is to examine the protections afforded to adults who are too sick to ..
- A national screening test for hearing, administered by telephone.Charles S Watson; Fiscal Year: 2013..and (2) it is made available by a consortium of two universities and a test- development company, none of which have any financial connections to the hearing aid industry and thus have no conflict of interest in the test outcomes.
- Novel Methods for Hemodialysis Access EvaluationWilliam F Weitzel; Fiscal Year: 2010..lectures and symposia on responsibility in research, responsible authorship, responsible data management, conflict of interest, and protections for human subjects in research...
- Molecular Modulation of Catalytic Sites of Escherichia coli F1Fo ATP SynthaseZulfiqar Ahmad; Fiscal Year: 2009..Professor Senior is retired leaving no conflict of interest. E. coli is easily amenable to molecular biology, biophysical, biochemical, and genetic techniques...
- Conference on Clinical Research for Rare DiseasesPeter A Merkel; Fiscal Year: 2012..for rare diseases research, 4) pathways for developing orphan products, 5) working with industry, 6) conflict of interest in rare diseases research, 7) the roles of patient advocacy groups in rare diseases research;;and 8) career ..
- Southwest Oncology Group Treatment GrantCharles D Blanke; Fiscal Year: 2013..moral and ethical conduct of clinical research by the group members is emphasized by ethics training, the conflict of interest policy, affirmation of integrity and data and safety monitoring...
- Veterinary Medical Student Research TrainingLESLIE GARRY ADAMS; Fiscal Year: 2013..Conduct of Research, emphasizing the ethical and humane use of animals in research, scientific misconduct, mentor-mentee relationships, responsible data management, conflict of interest, conflict of interest, and more.
- Int'l Center for Indigenous Phytotherapy Studies--TICIPSWilliam Folk; Fiscal Year: 2004..regulations on the conduct of research with human subjects and animal subjects, financial disclosure, conflict of interest and intellectual property rights...
- Board of Trustees: Systemic Conflict of Interest at Research UniversitiesSHEILA SLAUGHTER; Fiscal Year: 2007..research (with a focus on biomedical fields) by identifying the way research institutions deal with conflict of interest (COI) at the level of the institutions and their trustees...
- Human Subjects Protection Outreach-Education and ISLEONARD ZWELLING; Fiscal Year: 2003..abstract_text> ..
- Human Subjects Research Enhancements ProgramJames Patrick; Fiscal Year: 2003..BCM to further expand the types of data that are collected from this electronic platform, to facilitate conflict of interest reporting, to establish data-driven performance improvement standards guided by regulatory, accreditation ..
- Human Subjects Research Enhancements Program at MUSCJohn Raymond; Fiscal Year: 2003..g., biosafety, academic compliance (education, audits), and conflict of interest. These databases will be linked to the new IRB database, creating an array of relational databases that can ..
- DIFFICULT ETHICAL CHALLENGES IN EPIDEMIOLOGYKenneth Goodman; Fiscal Year: 2000..The role of the "company doctor" raises a problem in terms of conflict of interest, workplace testing and screening, international harmonization and cultural relativism...
- DIFFICULT ETHICAL CHALLENGES IN EPIDEMIOLOGYKenneth Goodman; Fiscal Year: 2001..The role of the "company doctor" raises a problem in terms of conflict of interest, workplace testing and screening, international harmonization and cultural relativism...
- Research Subjects Protection Program EnhancementsMARSHA ADDIS; Fiscal Year: 2002..and reliability of certain administrative and monitoring functions of the IRB, the CPRMC, and the Research Conflict of Interest committee; (B) Facilitate the use of electronic documents by the IRB and CPRMC for protocol review and ..
- Integrating and coordinating efforts in COPD guideline developmentHolger Schunemann; Fiscal Year: 2007..Conference participants will provide input regarding implementation products and on how to deal with conflict of interest. Outcomes: 1) Expert review of strengths and weaknesses of existing COPD guidelines; 2) Recommendations for ..
- Human Subjects Research Enhancements ProgramFrederick Samaha; Fiscal Year: 2003..Board, Radiation Safety Committee, Scientific Misconduct Committee, Institutional Biosafety Committee, Conflict of Interest Committee, and a Research Advocate Program for patients...
- Ethics and Safeguards in Psychiatric ResearchLaura W Roberts; Fiscal Year: 2010..e., institutional review, conflict of interest management, tissue/sample retention, &community consent)...
- Human Subjects Research Enhancements ProgramsWilliam Rosner; Fiscal Year: 2002..are new educational requirements dealing with the protection of human subjects and a real understanding of conflict of interest. SLRHC has put in place activities supporting both of these important mandates, as well as systems to ..
- Integrated Human Research Subjects Protection ProjectRoss McKinney; Fiscal Year: 2003..query the Research Data Repository (RDR) to determine whether the investigator has up-to-date training and conflict of interest information...
- Analysis and Design of a Database SystemREBECCA DAHL; Fiscal Year: 2002..and new program components, 2) Develop new program components including: education and training, financial conflict of interest, and adverse events, and 3) Design and create security measures to allow protection of data systems ..
- Authorship and Conflicts of Interest in Clinical TrailsWilliam Gardner; Fiscal Year: 2006..important data for discussions of editorial policies at scientific journals, for ethical standards and conflict of interest policies at universities and research institutions, and for ethics education in scientific training...
- WWW-BASED GENETICS CURRICULUM FOR MEDICAL STUDENTST Tanner; Fiscal Year: 2003..the above lessons including issues related to confidentiality of genetic information, provider bias, and conflict of interest. As necessary, each lesson will include basic discussions of molecular genetics, emerging technologies and ..
- Valid Consent/Refusal: A Core Competency for ResearchSusan Goold; Fiscal Year: 2006..Finally, learners demonstrate skills as they ask a "patient" to participate in research and disclose a conflict of interest. Simulated patient instructors (SPIs) are trained to play the part of the patient, assess the learner'..
- Human Subject Research Enhancement ProgramDavid Hamilton; Fiscal Year: 2003..3.Expand on goals of a recent grant from ORI in the "RCR Resource Development Program" on Conflict of Interest area to develop tools for IRB or "Conflict Management Committee" members, in multiple institutions, to ..
- Enhancements to KUMC Human Research ProtectionsTHOMAS NOFFSINGER; Fiscal Year: 2003..all institutional approvals for the conduct of human research, including biosafety, radiation safety, conflict of interest management, and data safety monitoring. 4...
- Trainee-Focusted Training for Research IntegritySteven Jacobsen; Fiscal Year: 2003..probe trainee perspectives before, immediately after, and one year after an RCR course on two key topics- Conflict of Interest and Authorship. 5...
- Dilemmas Academic Scientists FaceKAREN SEASHORE; Fiscal Year: 2004..The interviews will focus on the respondent's specific research programs, and activities that engender (or have engendered) the need to make decisions in each of the above areas. ..
- Human Subjects Research Enhancements ProgramEUGENE FEIGELSON; Fiscal Year: 2003..Foreign language translations of informed consent materials; . Fuller integration of the campus conflict of interest policy and procedure into the IRB review process; and ...
- Human Participants in Research Enhancement Program IIE Stinson; Fiscal Year: 2003..and compliance program, (4) improve communication between the four IRBs at WSU and the University Conflict of Interest Committee, and (5) collaborate with other institutions conducting human participant research but who do not ..
- Infrastructure for Human Research Protection Program-USARA ELLIS; Fiscal Year: 2003..The system will have functional linkages to our conflict of interest committees...
- Human Research Protections Programs and CollaborationsJOHN BRIGHTON; Fiscal Year: 2003..2. Linking the compliance review processes of the IRB to administrative processes of the conflict of interest review committee point of contact, the institutional biosafety committee, the radiation safety committee ..
- Government Industry Relationships in ScienceEric Campbell; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROMEMichael Camilleri; Fiscal Year: 2008..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
- Conflict of Interest in Clinical Practice Guideline DevelopmentSusan L Norris; Fiscal Year: 2010..Understanding the impact of industry relationships will help guideline sponsors to develop appropriate policies for managing conflict of interest.
- Data Sharing & Data Withholding Among Trainees in Scien*Eric Campbell; Fiscal Year: 2002..Hypotheses will be tested using univariate and multivariate statistical techniques. Results will be disseminated through publications in peer-reviewed journals and presentations at scientific meetings. ..
- ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBSMichael Camilleri; Fiscal Year: 2007..abstract_text> ..
- Academic Industry Relationships in GeneticsEric Campbell; Fiscal Year: 2006..Results will be disseminated through publications in peer-reviewed journals and presentations at scientific meetings. ..
- Academic Industry Relationships Among IRB MembersEric Campbell; Fiscal Year: 2005..Results will be disseminated through publications in peer-reviewed journals and presentations at scientific meetings. ..
- Research Integrity & Financial Conflicts of InterestPatricia Tereskerz; Fiscal Year: 2004..prevalence of various financial arrangements undertaken by investigators, that may constitute a financial conflict of interest; B) determine the national prevalence of various, questionable practices in the conduct and reporting of ..
- Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsMICHAEL L CAMILLERI; Fiscal Year: 2010..These actions may be relevant to develop new treatments for IBS. The studies will also provide further understanding of the potential of medications like medical marijuana on stomach function that may be relevant to appetite control. ..
- Evaluating Alcohol Brief Intervention ImplementationThomas Babor; Fiscal Year: 2006..abstract_text> ..
- Ethics and Clinical Trials in Advanced Cancer CareChristopher Daugherty; Fiscal Year: 2009....
- Delphi Evaluation of Alcohol Advertising CodesThomas Babor; Fiscal Year: 2009..abstract_text> ..
- Views of Privacy of Genetic InformationRobert Klitzman; Fiscal Year: 2005..The findings of this study can enhance further policy, professional and public education, and future research in this area. ..
- Evaluating industry codes governing malt liquor adsThomas Babor; Fiscal Year: 2003....
- A Qualitative Study of Editorial Decision-MakingLisa Bero; Fiscal Year: 2003..of the findings), author characteristics (such as institutional affiliation, funding source, and conflict of interest statement), organizational characteristics (such as number of competing papers and number of slots ..
- Views and Approaches Toward Research Integrity Among IRBsRobert Klitzman; Fiscal Year: 2007..We anticipate that the data from this study will serve as a significant foundation in assisting future research and the improvement of Rl through guidelines, education and other capacity building. [unreadable] [unreadable] [unreadable]..
- Brief Interventions for nicotine and cannabis useThomas Babor; Fiscal Year: 2007..unreadable] [unreadable]..
- Brief Intervention for Drug Abuse Using the WHO ASSISTThomas Babor; Fiscal Year: 2006....
- Management Decisions in Financial Conflicts of InterestLisa Bero; Fiscal Year: 2002..this same period; (3) Describe the processes used by the individual campuses to decide when a potential conflict of interest exists; (4) Define the factors that contribute to the decision-making processes regarding identification ..
- EFFECTS OF GENE PATENTS ON GENETIC TESTING AND RESEARCHMildred Cho; Fiscal Year: 2002..Our analysis will form inform public policy by indicating whether intellectual property policies or their implementation should be changed to encourage research and technology transfer, and if so, how. ..
- MUTATIONS, HORMONE THERAPY, AND VENOUS THROMBOEMBOLISMBruce Psaty; Fiscal Year: 2001....
- Trends in and Outcomes of Medication Use in Older AdultsBruce Psaty; Fiscal Year: 2004..abstract_text> ..
- Genome-wide case-only study of antihypertensive drug-gene interactionsBruce M Psaty; Fiscal Year: 2010....
- ANALYSIS OF TOBACCO DEPOSITIONS AND TRIAL TESTIMONYRonald Davis; Fiscal Year: 2003....
- Exacerbation of Alzheimer's Disease by Nitrous OxideW Kofke; Fiscal Year: 2003..Moreover, observation of a protective effect may result in discovery of an easily implemented preventative drug therapy for AD. ..
- Hormone Replacement Therapy and Prothrombotic VariantsBruce Psaty; Fiscal Year: 2005..Power for primary and secondary aims is excellent. Information from this project may help physicians counsel women about HRT to maximize either effectiveness, or safety, or both. ..
- Pharmacogenetics and Cardiovascular EventsBruce Psaty; Fiscal Year: 2006..The primary defense is replication: we would therefore welcome collaboration from others in the Pharmacogenetics Network in validation efforts. ..
- Analysis of Research Misconduct Policies: Surveys of OfficersREBECCA LIND; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- WGA Study to Identify Genetic Variants Associated with CV Events in CHSBruce Psaty; Fiscal Year: 2009..The proposed three-part study is efficient, has excellent power to detect small to modest-sized hazard ratios, provides a large sample of WG scans for aim 2, and includes an external replication. (End of Abstract) ..
- Effects of major changes in alcohol availabilityRobin Room; Fiscal Year: 2008..unreadable] [unreadable]..
- Disclosing Conflict of Interest to Research ParticipantsJeremy Sugarman; Fiscal Year: 2008..abstract_text> ..
- Respondent Burden and Retention in Cancer Clinical TrialsConnie Ulrich; Fiscal Year: 2009..Early identification and pre-emptive interventions prior to encountering retention problems in cancer clinical trials may mitigate respondent burden and lead to completion of important, resource intensive clinical trials. ..
- ANTIHYPERTENSIVE DRUG/GENE INTERACTIONS AND CV EVENTSBruce Psaty; Fiscal Year: 2004..58 (the difference between an odds ratio of 0.46 and 0.79 in subjects with and without the variant, respectively). Power for other primary aims is excellent; power for secondary aims is good to excellent. ..
- Competence to Consent in Schizophrenia ResearchScott Kim; Fiscal Year: 2005..abstract_text> ..