- Knock out, knock in, knock down--genetically manipulated mice and the Nobel Prize
John P Manis
Department of Pathology, Harvard Medical School, Children s Hospital, Boston, USA
N Engl J Med 357:2426-9. 2007
- An analysis of a wrong Nobel Prize-Johannes Fibiger, 1926: a study in the Nobel archives
Carl Magnus Stolt
Karolinska Institute, Department of Learning, Informatics, Management and Ethics, Stockholm, Sweden S 17177
Adv Cancer Res 92:1-12. 2004
- Robert Koch, the Nobel Prize, and the ongoing threat of tuberculosis
Stefan H E Kaufmann
Department of Immunology at the Max Planck Institute for Infection Biology, Berlin
N Engl J Med 353:2423-6. 2005
- [Researchers of the olfactory nerve function were awarded the Medicine and Physiology Nobel prize]
Suomen Terveystalo Oyj, Hemon lääkärikeskus, Lahti
Duodecim 120:2865-7. 2004
- Acidic lipids, H(+)-ATPases, and mechanism of oxidative phosphorylation. Physico-chemical ideas 30 years after P. Mitchell's Nobel Prize award
Biomime, Urbana, IL 61801, USA
Prog Biophys Mol Biol 99:20-41. 2009
Peter D. Mitchell, who was awarded the Nobel Prize in Chemistry 30 years ago, in 1978, formulated the chemiosmotic theory of oxidative phosphorylation...
- G-protein-coupled receptors and their (Bio) chemical significance win 2012 Nobel Prize in Chemistry
Hsi Hsien Lin
Department of Microbiology and Immunology, College of Medicine, Chang Gung University, Taoyuan, Taiwan
Biomed J 36:118-24. 2013
..The Nobel Prize in Chemistry for the year 2012 acknowledges the importance of GPCRs in these processes, especially for the ..
- Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research
W M Xu
Wolfson Institute for Biomedical Research, Rayne Institute, University College London
Cell Res 8:251-8. 1998
..This review will focus on the nitric oxide synthase gene family and recent progress on molecular genetic analysis of NOS1, NOS2 and NOS3 genes...
- Worm cast in starring role for Nobel prize
Nature 419:548-9. 2002
- Innate immunity's path to the Nobel Prize 2011 and beyond
Institute of Medicine Microbiology, Immunology and Hygiene, Technische Universitat Munchen, Trogerstr 30, Munchen, Germany
Eur J Immunol 42:1089-92. 2012
The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity...
- 100th anniversary of Robert Koch's Nobel Prize for the discovery of the tubercle bacillus
Stefan H E Kaufmann
Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
Trends Microbiol 13:469-75. 2005
The year 2005 marks the 100th anniversary of Robert Koch's Nobel Prize. Here, we describe the scientific career of Robert Koch, the discoverer of the etiologic agent of tuberculosis but also of those of anthrax, cholera and wound ..
- Prophet in his own country: Carlos Chagas and the Nobel Prize
Faculty of Medical Sciences, State University of Campinas SP UNICAMP, Brazil
Perspect Biol Med 46:532-49. 2003
..Chagas's name was repeatedly proposed for the Nobel Prize but he never received it; this hostile campaign may have been instrumental in costing him the award.
- Recent development of the mononuclear phagocyte system: in memory of Metchnikoff and Ehrlich on the 100th Anniversary of the 1908 Nobel Prize in Physiology or Medicine
Zong Liang Chang
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Biol Cell 101:709-21. 2009
..Additionally, I will honour the 100th anniversary of the 1908 Nobel Prize in Physiology or Medicine...
- Peter Agre, 2003 Nobel Prize winner in chemistry
Mark A Knepper
National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Room 6N260, 10 Center Drive MSC 1603, Bethesda, MD 20892 1603, USA
J Am Soc Nephrol 15:1093-5. 2004
Peter C. Agre, an American Society of Nephrology member, is the recipient of the 2003 Nobel Prize in Chemistry for his discovery of the aquaporin water channels...
- On viruses, discovery, and recognition
Robin A Weiss
MRC UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London W1T4JF, UK
Cell 135:983-6. 2008
This year's Nobel Prize in Physiology or Medicine rewards the discoverers of two viruses that cause major afflictions of humankind...
- Sources of funding for Nobel Prize-winning work: public or private?
Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, 45110, Greece
FASEB J 24:1335-9. 2010
..We analyzed the funding sources reported in the landmark scientific papers of Nobel Prize winners. Between 2000 and 2008, 70 Nobel laureates won recognition in medicine, physics, and chemistry...
- [Sydney Brenner, Robert Horvitz and John Sulston. Winners of the 2002 Nobel Prize in medicine or physiology. Genetic regulation of organ development and programmed cell death]
Institutionen för cell och molekylärbiologi, Karolinska Institutet, Stockholm
Lakartidningen 99:4026-32. 2002
- The 2005 Nobel Prize in physiology or medicine
Martin B Van Der Weyden
Med J Aust 183:612-4. 2005
..The Helicobacter story illustrates some of the human hallmarks of revolutionary research...
- Scientometric identification of elite 'revolutionary science' research institutions by analysis of trends in Nobel prizes 1947-2006
Bruce G Charlton
Med Hypotheses 68:931-4. 2007
..At present these elite institutions are found almost exclusively in the USA. The USA is apparently the only nation with a research system that nurtures revolutionary science on a large scale...
- Why there should be more science Nobel prizes and laureates - And why proportionate credit should be awarded to institutions
Bruce G Charlton
Med Hypotheses 68:471-3. 2007
..In future, the Nobel committee should also officially allocate proportionate credit to institutions for each laureate, and a historical task force could also award institutional credit for past prizes...
- [The Nobel Prize in Physiology or Medicine for 2006 for the discovery of RNA interference]
Nederlands Kanker Instituut Antoni van Leeuwenhoek Ziekenhuis, afd Moleculaire Carcinogenese, Amsterdam
Ned Tijdschr Geneeskd 150:2849-53. 2006
The Nobel Prize in Physiology or Medicine has been awarded to Andrew Fire and Craig Mello for their discovery of RNA interference, i.e. the suppression of gene activity by double-stranded RNA...
- A humble bacterium sweeps this year's Nobel Prize
INSERM ERI 10, Laboratoire de Bacteriologie, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Cell 123:975-6. 2005
- The Nobel Prize of 1906
Ronald S Fishman
Arch Ophthalmol 125:690-4. 2007
December 2006 marked 100 years since the Nobel Prize in Physiology or Medicine was awarded jointly to 2 pioneers in the cellular anatomy of the central nervous system (CNS), Camillo Golgi and Santiago Ramon y Cajal...
- Love at first smell--the 2004 Nobel Prize in Physiology or Medicine
Rockefeller University, New York, USA
N Engl J Med 351:2579-80. 2004
- The contributions of Paul Ehrlich to pharmacology: a tribute on the occasion of the centenary of his Nobel Prize
Esteve Foundation, Barcelona, Spain
Pharmacology 82:171-9. 2008
On the centenary of Paul Ehrlich's Nobel Prize, this German researcher deserves to be remembered as a pioneer in a large number of scientific disciplines...
- Ilya Ilich Metchnikoff (1845-1915) and Paul Ehrlich (1854-1915): the centennial of the 1908 Nobel Prize in Physiology or Medicine
Frank C Schmalstieg
University of Texas Medical Branch, Galvseton, Texas 77555 0369, USA
J Med Biogr 16:96-103. 2008
Ilya Metchnikoff and Paul Ehrlich shared the 1908 Nobel Prize in Physiology or Medicine - Metchnikoff for discovering the major types and functions of phagocytes and Ehrlich for discovering the types of blood leukocytes, helping to ..
- From nerves and hormones to bacteria in the stomach; Nobel prize for achievements in gastrology during last century
S J Konturek
Department of Clinical Physiology, Jagiellonian University College of Medicine, Cracow, Poland
J Physiol Pharmacol 56:507-30. 2005
..P. Pavlov at the end of 19th century of neuro-reflex stimulation of secretion of this acid that was awarded by Nobel prize in 1904. Then, J. W. Black, who followed L...
- Yellow fever and Max Theiler: the only Nobel Prize for a virus vaccine
Center for the History of Science, The Royal Swedish Academy of Sciences, SE 104 05 Stockholm, Sweden
J Exp Med 204:2779-84. 2007
In 1951, Max Theiler of the Rockefeller Foundation received the Nobel Prize in Physiology or Medicine for his discovery of an effective vaccine against yellow fever--a discovery first reported in the JEM 70 years ago...
- Nobel Prize in Chemistry. Mastering macromolecules
Science 298:527-8. 2002
- The 2011 Nobel Prize in physiology or medicine
Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
Scand J Immunol 75:1-4. 2012
..Ralph M. Steinman received the award for the discovery of dendritic cells, a cell type bridging innate and adaptive immunity, and how these cells orchestrate immune responses...
- The first nobel prize for integrated systems physiology: Ivan Petrovich Pavlov, 1904
Jackie D Wood
College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA
Physiology (Bethesda) 19:326-30. 2004
- The 2003 Nobel Prize for MRI: significance and impact
C Leon Partain
J Magn Reson Imaging 19:515. 2004
- [The 2009 Nobel Prize in Medicine and its surprising message: lifestyle is associated with telomerase activity]
Semmelweis Egyetem, Általános Orvostudományi Kar, Genetikai Sejt és Immunbiológiai Intézet, Budapest
Orv Hetil 151:965-70. 2010
The 2009 Nobel Prize in Physiology and Medicine was awarded to three scientists for their pioneer research on telomeres - and the enzyme that forms them - telomerase...
- Water channel proteins: from their discovery in 1985 in Cluj-Napoca, Romania, to the 2003 Nobel Prize in Chemistry
Department of Cell and Molecular Biology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj Napoca, Romania
Cell Mol Biol (Noisy-le-grand) 52:10-9. 2006
..first water channel by Benga's group must be properly credited; the omission of Gheorghe Benga from the 2003 Nobel Prize in Chemistry (half of which was awarded to Peter Agre "for the discovery of the water channels") was a new ..
- GFP: from jellyfish to the Nobel prize and beyond
Chemistry Department, Connecticut College, New London, CT 06320, USA
Chem Soc Rev 38:2823-32. 2009
On December 10, 2008 Osamu Shimomura, Martin Chalfie and Roger Tsien were awarded the Nobel Prize in Chemistry for "the discovery and development of the green fluorescent protein, GFP"...
- Polio and Nobel prizes: looking back 50 years
Center for History of Science, The Royal Swedish Academy of Sciences, Stockholm, Sweden
Ann Neurol 61:385-95. 2007
In 1954, John Enders, Thomas Weller, and Frederick Robbins were awarded the Nobel Prize in Physiology or Medicine "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue...
- Nobel Prize in Physiology or Medicine. HIV, HPV researchers honored, but one scientist is left out
Science 322:174-5. 2008
- Mortality and immortality: the Nobel Prize as an experiment into the effect of status upon longevity
Matthew D Rablen
University of Warwick, Coventry, United Kingdom
J Health Econ 27:1462-71. 2008
..This paper attempts to formulate a test in that spirit. It collects 19th-century birth data on science Nobel Prize winners...
- Nobel Prize in Physiology or Medicine. Method to silence genes earns loud praise
Science 314:34. 2006
- Nobel Prize honors HIV, HPV discoveries
JAMA 300:2109. 2008
- The 1932 and 1944 Nobel Prizes in physiology or medicine: rewards for ground-breaking studies in neurophysiology
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Hist Neurosci 15:341-57. 2006
In 1932 Sherrington and Adrian were awarded the Nobel Prize in Physiology or Medicine "for their discoveries regarding the functions of neurons" and in 1944 Erlanger and Gasser were awarded the same prize "for their discoveries relating ..
- Portrait of Science. Scientist, technologist, proto-feminist, superstar
Roger M Macklis
Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Science 295:1647-8. 2002
..By nature shy and reserved, Marie's fame, as both a scientist and as an exemplar of a liberated professional woman of the roaring twenties, grew to superstar proportions...
- Spectroscopic view of life and work of the Nobel Laureate Sir C.V. Raman
Amrith Raj Rao
Department of Urology, Wexham Park Hospital, Slough, UK
J Endourol 21:8-11. 2007
..V. Raman of India, who in 1930 brought the Nobel Prize in Physics to the East side of Suez. We present the life and work of Sir C.V...
- [Closing words of the Minister of Education and Science]
Jesús San Segundo Gomez de Cadiñanos
An R Acad Nac Med (Madr) 123:299-303. 2006
- Berson, Yalow, and the JCI: the agony and the ecstasy
C Ronald Kahn
J Clin Invest 114:1051-4. 2004
..two years passed between the initial experiments in dogs to widespread human application to the awarding of the Nobel Prize in 1923...
- [Karl Landsteiner (1868-1943) and the specificity of serological reactions, one hundred years ago and now]
K de Meer
VU Medisch Centrum, afd Kindergeneeskunde, Postbus 7075, 1007 MB Amsterdam
Ned Tijdschr Geneeskd 146:575-9. 2002
..his discovery of the AB0 blood groups, the monumental work of Austrian physician Karl Landsteiner (1868-1943, Nobel Prize 1930) on the specificity of serological reactions is widely recognised...
- [Einthoven: the man and his invention]
Servicio de Salud Concepción
Rev Med Chil 132:260-4. 2004
Einthoven, a Dutch physician, was awarded the Nobel Prize for Physiology or Medicine for his discovery of the mechanism of the electrocardiogram. He was born on May 21, 1860, in Semarang, on the island of Java...
- Lord Rayleigh: John William Strutt, third Baron Rayleigh
Peter N T Wells
Institute of Medical Engineering and Medical Physics, Cardiff University, School of Engineering, Queen s Buildings, The Parade, Cardiff CF24 3AA, UK
IEEE Trans Ultrason Ferroelectr Freq Control 54:591-6. 2007
..He received the 1904 Nobel Prize in Physics for the discovery of argon and made numerous seminal contributions to scientific progress...
- [Women the thought and works of Cajal (remembrances on the 100th anniversary of the Nobel Prize Award)]
Julio Cruz Hermida
An R Acad Nac Med (Madr) 123:689-707; discussion 707-10. 2006
..The conference finishes with an account of the last moments of Cajal and the moving words by D. Teófilo Hernando, who was at the side of the Maestro when he passed away...
- Robert Koch
Freie Universitat Berlin, Institut fur Geschichte der Medizin, Klingsorstr 119, 12203, Berlin, Germany
Microbes Infect 5:69-74. 2003
..By chronologically following Koch's work on anthrax, germ photography and tuberculosis, it shows how the visual representation of germs transformed laboratory research in medical science...
- [Albert Claude, an exceptional man]
Bull Mem Acad R Med Belg 161:543-55. 2006
- Sir Howard Walter Florey--the force behind the development of penicillin
B Lee Ligon
Department of Pediatrics, Baylor College of Medicine, 66212 Fannin, A 150, Houston, TX 77030, USA
Semin Pediatr Infect Dis 15:109-14. 2004
..They, along with Fleming, were given the 1945 Nobel Prize in Physiology or Medicine for their roles in the discovery and development of this agent...
- The origins of protein phosphorylation
MRC Protein Phosphorylation Unit, School of Life Sciences, University of Dundee, Scotland, UK
Nat Cell Biol 4:E127-30. 2002
..Here I review the discovery of protein phosphorylation and give a personal view of the key findings that have helped to shape the field as we know it today...
- [In memoriam: Niels Ryberg Finsen]
H D Göring
Hautklinik und Immunologisches Zentrum, Städtisches Klinikum Dessau, Dessau
Hautarzt 55:753-5. 2004
Niels Ryberg Finsen who won the Nobel Prize in Medicine in 1903 for introducing phototherapy for lupus vulgaris...
- The first Nobel Peace Prize, Henry Dunant (founder of the International Red Cross) and his "Mémoirs"
Clinical Biochemistry Laboratory, IOT, Florence, Italy
Vesalius 9:20-7. 2003
..The authors' intention is to give due recognition to Dunant for his work, and to highlight the humanity and the moral and social worth of the face behind the International Red Cross...
- "Who's on first?" - medical discoveries and scientific priority
Center for the History of Medicine, University of Michigan Medical School, Ann Arbor, USA
N Engl J Med 351:2792-4. 2004
- Revisiting the 1981 Nobel Prize to Roger Sperry, David Hubel, and Torsten Wiesel on the occasion of the centennial of the Prize to Golgi and Cajal
University of Verona, Verona, Italy
J Hist Neurosci 15:369-75. 2006
In 1981 the Nobel Prize for Medicine or Physiology was awarded to Roger Sperry for his work on the functional specialization of the cerebral hemispheres, and to David Hubel and Torsten Wiesel for their work on information processing in ..
- The making of a physician-scientist--the process has a pattern: lessons from the lives of Nobel laureates in medicine and physiology
Stephen L Archer
Department of Medicine Cardiology and the Vascular Biology Group, University of Alberta, Edmonton, Canada
Eur Heart J 28:510-4. 2007
..Further inspiration comes from those great researchers whose contributions shaped Medicine but did not lead to the Prize...
- The scientific roots of José A. Campos-Ortega, a German neurobiologist born in Spain
Departamento de Bioquímica de la Universidad Autónoma de Madrid, Instituto de Investigaciones Biomedicas Alberto Sols, UAM CSIC, C Arzobipo Morcillo 4, Madrid 28029, Spain
Dev Dyn 235:855-60. 2006
..Campos-Ortega and the studies he undertook. Particular emphasis will be placed on how these early experiences shaped his personality and his future scientific contributions...
- Giuseppe Levi: mentor of three Nobel laureates
Department of Morphological and Biomedical Sciences, University of Verona, Verona, Italy
J Hist Neurosci 15:358-68. 2006
..Rita Levi-Montalcini, who was awarded the Nobel Prize (1986) for the discovery of Nerve Growth Factor, was stimulated and assisted in her work by Giuseppe Levi ..
- [The Nobel Prize in Physiology or Medicine for 2005 for the discovery of the stomach bacterium Helicobacter pylori]
J H Kleibeuker
Universitair Medisch Centrum Groningen, afd Maag, Darm en Leverziekten, Postbus 30 001, 9700 RB Groningen
Ned Tijdschr Geneeskd 149:2955-7. 2005
This year, the Nobel Prize in Physiology or Medicine was awarded to the Australian doctors Marshall and Warren for their discovery and further identification of the stomach bacterium Helicobacter pylori...
- Robert Koch: the grandfather of cloning?
Robin A Weiss
Wohl Virion Centre, Division of Infection and Immunity, University College London, London W1T 4JF, United Kingdom
Cell 123:539-42. 2005
This year marks the centenary of Robert Koch's Nobel Prize for discovering the cause of tuberculosis. Koch was also the first scientist to isolate the anthrax and cholera microbes...
- [Recording instruments in the physiology of the late nineteenth century]
Dipartimento di Filosofia, Universita di Torino, I
Med Secoli 17:95-122. 2005
..The contributions in the field of vacuum-tube methods completed the development and the progress in the analysis of the action potential of nerve...
- Nobel laureates at the Stazione Zoologica Anton Dohrn: phenomenology and paths to discovery in neuroscience
History of Science Unit and Historical Archives, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples, Italy
J Hist Neurosci 15:376-95. 2006
..a survey of the Zoological Station's contribution to neurosciences, especially to the Naples experience of the Nobel Prize winner Sir Bernard Katz and his assistant Ricardo Miledi, between 1965 and 1970...
- Yeast and cancer
Leland H Hartwell
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Biosci Rep 24:523-44. 2004
..The discovery of genes that control cell division in yeast, and their relation to cancer, is reviewed...
- [The marksman of medicine, Paul Ehrlich (1854-1915)]
Orv Hetil 146:1499-502. 2005
- Werner Forssmann, Eberswalde, the 1956 Nobel Prize for medicine
Director em of the Institute for Cardiology and Sports Medicine, German Sport University, 50933 Cologne, Germany
Eur J Med Res 11:409-12. 2006
..After the notification that Werner Forssmann had been awarded the Nobel Prize for Medicine in 1956, Hugo Wilhelm Knipping instructed me to help Werner Forssmann with the preparation of his ..
- [Maximilian Mehl and the treatment with concentrated sunlight]
Institut für Geschichte der Medizin der Heinrich Heine Universität Düsseldorf
Dtsch Med Wochenschr 131:2920-4. 2006
..In 1903 Finsen was awarded the Nobel Prize for his work while Mehl's discovery remained practically unknown...
- RNA interference: big applause for silencing in Stockholm
Phillip D Zamore
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA
Cell 127:1083-6. 2006
..For this landmark discovery, Mello and Fire are honored with this year's Nobel Prize in Physiology or Medicine.
- A long time in the making--the Nobel Prize for RNA polymerase
Department of Bacteriology, 420 Henry Mall, University of Wisconsin Madison, Madison, WI 53706, USA
Cell 127:1087-90. 2006
The 2006 Nobel Prize in Chemistry has been awarded to Roger Kornberg for elucidating the molecular basis of eukaryotic transcription...
- Portraits of science. Mosquitoes bite more than once
W F Bynum
Wellcome Trust Centre for the History of Medicine at University College London, 24 Eversholt Street, London NW1 1AD, UK
Science 295:47-8. 2002
..This discovery won him a Nobel Prize in 1902, but the route to this success was by no means clear...
- [Women in natural sciences--Nobel Prize winners]
Skola narodnog zdravlja Andrija Stampar, Medicinski fakultet, Sveuciliste u Zagrebu
Acta Med Croatica 60:1-5. 2006
..life and accomplishments of Alfred Bernhard Nobel are described as well as scientific achivements of 11 women, Nobel prize winners in the field of physics, chemistry, physiology and/or medicine...
- The discovery of chemical neurotransmitters
Elliot S Valenstein
Department of Psychology, University of Michigan, Ann Arbor 48109 1109, USA
Brain Cogn 49:73-95. 2002
- The Nobel trail of Vincent du Vigneaud
Department of Biochemistry and Organic Chemistry, University of Uppsala, Biomedical Center, SE 751 23 Uppsala, Sweden
J Pept Sci 13:431-3. 2007
The Nobel Prize for chemistry of 1955 was awarded to Vincent du Vigneaud. After a brief outline of his career and accomplishments, some archive material related to this decision of the Royal Swedish Academy of Sciences is presented...
- Cyclic nucleotide research -- still expanding after half a century
Joseph A Beavo
Department of Pharmacology, University of Washington, Seattle, Washington 98195 7280, USA
Nat Rev Mol Cell Biol 3:710-8. 2002
..The breadth and impact of this work is reflected by five different Nobel prizes...
- Bose-Einstein condensation in a dilute gas: the first 70 years and some recent experiments (Nobel Lecture)
Eric A Cornell
Department of Physics, University of Colorado, NIST National Institute of Standards and Technology, Boulder, CO 80309 0440, USA
Chemphyschem 3:476-93. 2002
..After an initial process of laser cooling (which itself won its developers the 1997 Nobel Prize), atoms in a magnetic-optical trap must be safely transferred into a purely magnetic trap, where the ..
- Robert Koch: Nobel laureate and controversial figure in tuberculin research
B Lee Ligon
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Semin Pediatr Infect Dis 13:289-99. 2002
- [50 years after the discovery of the DNA structure its implications still have not reached clinical practice. Our genetic material is "a big tangle of nucleic acids and proteins"]
Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, Stockholm
Lakartidningen 100:2218-21. 2003
..Many researchers and clinicians are hoping that the tangle of nucleic acids and proteins that fills the cellular nucleus harbours interesting and potential drug targets...
- Pictures of Dorothy Hodgkin
Clare College, CB2 1TL, Cambridge, UK
Endeavour 27:85-6. 2003
..Although Hambling's picture features a model of insulin, it is very different from photographs celebrating the discovery of DNA...
- The impossible interview with the man of the hidden biological structures. Interview by Paolo Mazzarello
Department of Experimental Medicine, Section of General Pathology C Golgi Pavia, Italy
J Hist Neurosci 15:318-25. 2006
..The Italian Professor Golgi from Pavia has been awarded the Nobel Prize for Physiology or Medicine ex aequo with the Spanish anatomist Santiago Ramón y Cajal...
- Are statistical contributions to medicine undervalued?
Norman E Breslow
Department of Biostatistics, Box 357232, University of Washington, Seattle, Washington 98195 7232, USA
Biometrics 59:1-8. 2003
Econometricians Daniel McFadden and James Heckman won the 2000 Nobel Prize in economics for their work on discrete choice models and selection bias...
- Biography: Selman A. Waksman, PhD (1888-1973): pioneer in development of antibiotics and Nobel Laureate
B Lee Ligon-Borden
Baylor College of Medicine, Houston, TX 77030, USA
Semin Pediatr Infect Dis 14:60-3. 2003
Selman Abraham Waksman is regarded today as the foremost authority on soil biology. A Nobel Prize recipient for his work on antibiotics, he also coined the term...
- Interview with Dr Joseph Murray (by Francis L Delmonico)
Am J Transplant 2:803-6. 2002
The Editors asked Dr Delmonico to interview Dr Joseph Murray, winner of the Nobel prize in Medicine 1990 for performing the first successful renal transplant, to record recollections of the issues of the 1950s, when clinical ..
- A meaningful legacy: urologists as Nobel Prize laureates
The Prostate Centre at Vancouver General Hospital, Vancouver, BC, Canada
Can J Urol 10:1737-42. 2003
To review the careers of two urologists among Nobel Prize-winners in medicine, W. Forssmann and C. H. Huggins, and the significance of their contributions.
- Nobel Lecture. Protein synthesis, proteolysis, and cell cycle transitions
Cancer Research UK, Clare Hall Laboratories, South Mimms, Herts EN6 3LD, United Kingdom
Biosci Rep 22:465-86. 2002
..The discovery of the role(s) of protein synthesis and degradation in the operation of the cell cycle is described...
- Reflections: Fritz Haber and the ambiguity of ethics
Ryan J Huxtable
Proc West Pharmacol Soc 45:1-3. 2002
- Man of destiny: the life and work of Fritz Haber
Keith L Manchester
University of the Witswatersrand, Johannesburg, South Africa
Endeavour 26:64-9. 2002
..Haber was indeed a great and versatile scientist, but his was also a vigorous and complex personality that interacted in unexpected ways with the social and political circumstances of his time...
- Nobel prize winner trading card (CIRCA 1952). Elie Metchnikoff
Dale E Hammerschmidt
J Lab Clin Med 141:229-30. 2003
..Metchnikoff supposed that old age was avoidable, and subscribed to the materialistic school of thought. He was awarded the Nobel Prize in 1908. (With the complements of the Jose Lopez Luis Cigarillo Factory, Tenerife).
- Professor Bernardo Alberto Houssay, MD (1887-1971): Argentine physiologist and Nobel laureate
Barbara J Hawgood
J Med Biogr 12:71-6. 2004
..He was joint winner of the Nobel Prize for Physiology or Medicine in 1947 for his discovery of the role of the anterior pituitary in carbohydrate ..
- The crystallization of enzymes and virus proteins: laying to rest the colloidal concept of living systems
Keith L Manchester
School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, Wits 2050, South Africa
Endeavour 28:25-9. 2004
In 1946 three Americans shared the Nobel Prize for Chemistry--James Sumner 'for his discovery that enzymes can be crystallized', and John Northrop and Wendell Stanley 'for their preparation of enzymes and virus proteins in a pure form'...
- Nobel Lecture. Yeast and cancer
Leland H Hartwell
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, DI 060, Seattle, WA 98109 1024, USA
Biosci Rep 22:373-94. 2002
..The discovery of genes that control cell division in yeast, and their relation to cancer, is reviewed...
- The centennial of the Einthoven electrocardiogram
Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
J Electrocardiol 35:123-9. 2002
..For his work, Einthoven received the Nobel Prize.
- The contribution of Camillo Golgi to our understanding of the structure of the nervous system
Arch Ital Biol 145:111-5. 2007
A hundred years ago Camillo Golgi and Santiago Ramón y Cajal were awarded the Nobel Prize for Physiology or Medicine for their investigations on the structure of the nervous system...
- [The contribution of the Nobel laureates to biochemistry and molecular biology]
Iu M Levchuk
Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv
Ukr Biokhim Zh (1999) 75:128-50. 2003
The Nobel Prize winners works are considered and analyzed. Main attention is paid to the works devoted to biochemistry or problems related to biochemistry. The most prominent biochemical investigations are considered in detail...
- Monoclonal antibodies in the prehybridoma era: a brief historical perspective and personal reminiscence
M J Stone
Department of Oncology, Baylor Charles A Sammons Cancer Center, Dallas, TX 75246, USA
Clin Lymphoma 2:148-54. 2001
Emil von Behring, an immunologist, received the first Nobel Prize in Physiology or Medicine in 1901 for his studies on serum therapy of diphtheria...
- Novel agents and strategies to treat herpes simplex virus infections
Expert Opin Investig Drugs 12:165-83. 2003
..Notable in this regard was the award of a Nobel Prize in 1988 for the elucidation of mechanistic principles which resulted in the development of new drugs such as ..
- Helicobacter pylori and its involvement in gastritis and peptic ulcer formation
S J Konturek
Department of Clinical Physiology, Jagiellonian University Medical College, Cracow, Poland
J Physiol Pharmacol 57:29-50. 2006
..P. Pavlov of neuro-reflex stimulation of gastric secretion for which he was awarded first Nobel Prize in 1904...
- Amphibians as animal models for laboratory research in physiology
Warren W Burggren
Department of Biological Sciences, University of North Texas, Denton, Texas 76203 5220, USA
ILAR J 48:260-9. 2007
..especially true in physiological research, as evident from the high profile of amphibians as animal models in Nobel Prize research...
- From α-arylation of olefins to acylation with aldehydes: a journey in regiocontrol of the Heck reaction
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom
Acc Chem Res 44:614-26. 2011
..of olefins with aryl halides, more often simply called the Heck reaction, was recently recognized with the 2010 Nobel Prize in chemistry...
- [Prostate cancer. Treatment]
Service d Urologie, Centre Hospitalier Universitaire de Brest, Hopital de la Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest, France
Ann Urol (Paris) 38:225-58. 2004
..sensitivity characterizes prostate cancer; it has been discovered more than 50 years ago by Charles Huggins (Nobel prize-winner)...
- [Axel Holst and Theodor Frolich--pioneers in the combat of scurvy]
Kaare R Norum
Institutt for ernaeringsforskning Universitetet i Oslo Postboks 1046 Blindern 0316 Oslo
Tidsskr Nor Laegeforen 122:1686-7. 2002
..The crucial factor, Vitamin C, was discovered in 1930 by Albert Szent-Györgyi, for which he was rewarded the Nobel Prize. No prizes or proper recognition were awarded Holst and Frølich at the time...
- [Mathematics, natural sciences and technology--parts of the encyclopedia Die Kultur der Gegenwart (The culture of today)]
Ber Wiss 31:29-43. 2008
..for the mathematical, natural scientific and engineering parts of culture as well as their reasons, to win Nobel prize winners and other famous scientists to become co-editors and authors...