infection control

Summary

Summary: Programs of disease surveillance, generally within health care facilities, designed to investigate, prevent, and control the spread of infections and their causative microorganisms.

Top Publications

  1. ncbi Mathematical modelling: a tool for hospital infection control
    H Grundmann
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Lancet Infect Dis 6:39-45. 2006
  2. ncbi An intervention to decrease catheter-related bloodstream infections in the ICU
    Peter Pronovost
    School of Medicine, Johns Hopkins University, Baltimore, USA
    N Engl J Med 355:2725-32. 2006
  3. ncbi Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee
    A J Mangram
    Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Infect Control 27:97-132; quiz 133-4; discussion 96. 1999
  4. ncbi Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme
    D Pittet
    Department of Internal Medicine, University of Geneva Hospitals, and Institute of Social and Preventive Medicine, University of Geneva, Switzerland
    Lancet 356:1307-12. 2000
  5. ncbi Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections
    Rajiv Jain
    Patient Care Services, Veterans Affairs Central Office, and the VA Pittsburgh Healthcare System, Pittsburgh, USA
    N Engl J Med 364:1419-30. 2011
  6. pmc Modeling the invasion of community-acquired methicillin-resistant Staphylococcus aureus into hospitals
    Erica M C D'Agata
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 48:274-84. 2009
  7. ncbi Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs
    Craig A Umscheid
    Center for Evidence Based Practice, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 32:101-14. 2011
  8. ncbi Role of hand hygiene in healthcare-associated infection prevention
    B Allegranzi
    First Global Patient Safety Challenge, World Alliance for Patient Safety, IER PSP, Room L319, L Building, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    J Hosp Infect 73:305-15. 2009
  9. pmc Intervention to reduce transmission of resistant bacteria in intensive care
    W Charles Huskins
    Division of Pediatric Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA
    N Engl J Med 364:1407-18. 2011
  10. ncbi SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, UPMC P, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 24:362-86. 2003

Detail Information

Publications295 found, 100 shown here

  1. ncbi Mathematical modelling: a tool for hospital infection control
    H Grundmann
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Lancet Infect Dis 6:39-45. 2006
    ..infections caused by antibiotic-resistant pathogens have become a menace in hospitals worldwide and infection control measures have lead to vastly different outcomes in different countries...
  2. ncbi An intervention to decrease catheter-related bloodstream infections in the ICU
    Peter Pronovost
    School of Medicine, Johns Hopkins University, Baltimore, USA
    N Engl J Med 355:2725-32. 2006
    ..Catheter-related bloodstream infections occurring in the intensive care unit (ICU) are common, costly, and potentially lethal...
  3. ncbi Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee
    A J Mangram
    Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Infect Control 27:97-132; quiz 133-4; discussion 96. 1999
    ..II, "Recommendations for Prevention of Surgical Site Infection," represents the consensus of the Hospital Infection Control Practices Advisory Committee (HICPAC) regarding strategies for the prevention of SSIs...
  4. ncbi Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme
    D Pittet
    Department of Internal Medicine, University of Geneva Hospitals, and Institute of Social and Preventive Medicine, University of Geneva, Switzerland
    Lancet 356:1307-12. 2000
    ..We attempted to promote hand hygiene by implementing a hospital-wide programme, with special emphasis on bedside, alcohol-based hand disinfection. We measured nosocomial infections in parallel...
  5. ncbi Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections
    Rajiv Jain
    Patient Care Services, Veterans Affairs Central Office, and the VA Pittsburgh Healthcare System, Pittsburgh, USA
    N Engl J Med 364:1419-30. 2011
    ..Health care-associated infections with methicillin-resistant Staphylococcus aureus (MRSA) have been an increasing concern in Veterans Affairs (VA) hospitals...
  6. pmc Modeling the invasion of community-acquired methicillin-resistant Staphylococcus aureus into hospitals
    Erica M C D'Agata
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 48:274-84. 2009
    ..If true, this event would have serious consequences, because CA-MRSA infections in hospitals would occur among a more debilitated, older patient population...
  7. ncbi Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs
    Craig A Umscheid
    Center for Evidence Based Practice, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 32:101-14. 2011
    ..To estimate the proportion of healthcare-associated infections (HAIs) in US hospitals that are "reasonably preventable," along with their related mortality and costs...
  8. ncbi Role of hand hygiene in healthcare-associated infection prevention
    B Allegranzi
    First Global Patient Safety Challenge, World Alliance for Patient Safety, IER PSP, Room L319, L Building, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    J Hosp Infect 73:305-15. 2009
    ..We also report considerations and solutions resulting from the implementation of the multimodal strategy proposed in the WHO Guidelines on Hand Hygiene in Health Care...
  9. pmc Intervention to reduce transmission of resistant bacteria in intensive care
    W Charles Huskins
    Division of Pediatric Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA
    N Engl J Med 364:1407-18. 2011
    ..Intensive care units (ICUs) are high-risk settings for the transmission of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcus (VRE)...
  10. ncbi SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, UPMC P, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 24:362-86. 2003
    b>Infection control programs were created three decades ago to control antibiotic-resistant healthcare-associated infections, but there has been little evidence of control in most facilities...
  11. pmc Hospital epidemiology and infection control in acute-care settings
    Emily R M Sydnor
    Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Clin Microbiol Rev 24:141-73. 2011
    ..Growing rates of HAIs alongside evidence suggesting that active surveillance and infection control practices can prevent HAIs led to the development of hospital epidemiology and infection control programs...
  12. ncbi Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Prof
    John M Boyce
    Hospital of Saint Raphael, New Haven, Connecticut, USA
    MMWR Recomm Rep 51:1-45, quiz CE1-4. 2002
    ..Recommendations concerning related issues (e.g., the use of surgical hand antiseptics, hand lotions or creams, and wearing of artificial fingernails) are also included...
  13. ncbi The efficacy of infection control interventions in reducing the incidence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the nonoutbreak setting: A systematic review
    Shannon Goddard
    Department of Medicine, University of Toronto, Canada
    Am J Infect Control 39:599-601. 2011
    We conducted a systematic review to examine the efficacy of infection control interventions for the control of ESBL-producing Enterobacteriaceae in hospitals in the non-outbreak setting...
  14. ncbi Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals
    Ari Robicsek
    Evanston Northwestern Healthcare and Northwestern University Feinberg School of Medicine, Evanston, Illinois 60201, USA
    Ann Intern Med 148:409-18. 2008
    ..The effect of large-scale expanded surveillance for methicillin-resistant Staphylococcus aureus (MRSA) on health care-associated MRSA disease is not known...
  15. ncbi Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients
    Stephan Harbarth
    Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
    JAMA 299:1149-57. 2008
    ..Experts and policy makers have repeatedly called for universal screening at hospital admission to reduce nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection...
  16. ncbi Infection control measures for norovirus: a systematic review of outbreaks in semi-enclosed settings
    J P Harris
    Gastrointestinal, Emerging and Zoonotic Diseases Department, Health Protection Agency, Centre for Infections, 61 Colindale Avenue, Colindale, London NW9 5EQ, UK
    J Hosp Infect 74:1-9. 2010
    ..We found no evidence that implementing infection control measures affected the duration of outbreaks, or the attack rates either overall (all settings combined) or ..
  17. ncbi Infection control in the management of highly pathogenic infectious diseases: consensus of the European Network of Infectious Disease
    Philippe Brouqui
    Department of Infectious Diseases and Tropical Medicine, CHU Nord and URMITE IRD CNRS UMR 6236, Marseille, France
    Lancet Infect Dis 9:301-11. 2009
    ..for Infectious Diseases (EUNID) is a network of clinicians, public health epidemiologists, microbiologists, infection control, and critical-care doctors from the European member states, who are experienced in the management of ..
  18. ncbi National influences on catheter-associated bloodstream infection rates: practices among national surveillance networks participating in the European HELICS project
    S Hansen
    Institute for Hygiene and Environmental Medicine, Charite University Medicine Berlin, Berlin, Germany
    J Hosp Infect 71:66-73. 2009
    ..rates) in European intensive care units (ICUs) as part of the HELICS project (Hospitals in Europe Link for Infection Control through Surveillance)...
  19. ncbi The effectiveness of interventions aimed at increasing handwashing in healthcare workers - a systematic review
    S Naikoba
    Department of Public Health and Epidemiology, University of Nottingham, Nottingham, UK
    J Hosp Infect 47:173-80. 2001
    ..Multifaceted approaches which combine education with written material, reminders and continued feedback of performance can have an important effect on handwashing compliance and rates of hospital-acquired infection...
  20. ncbi Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures
    Mary K Hayden
    Dept of Medicine and Pathology, Rush University Medical Center, Chicago, IL 60612, USA
    Clin Infect Dis 42:1552-60. 2006
    ..Using vancomycin-resistant enterococci (VRE) as a marker organism, we investigated the effects of improved environmental cleaning with and without promotion of hand hygiene adherence on the spread of VRE in a medical intensive care unit...
  21. pmc Risk factors for new detection of vancomycin-resistant enterococci in acute-care hospitals that employ strict infection control procedures
    Alexander A Padiglione
    Department of Infectious Diseases, Monash Medical Centre, Clayton, Victoria, Australia
    Antimicrob Agents Chemother 47:2492-8. 2003
    ..hematology, renal, transplant, and intensive care) in three teaching hospitals that used identical strict infection control and isolation procedures for VRE to minimize nosocomial spread...
  22. ncbi Use of benchmarking and public reporting for infection control in four high-income countries
    Thomas Haustein
    Infection Control Programme, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Lancet Infect Dis 11:471-81. 2011
    ..An opportunity now exists to learn from the different strategies that have been adopted...
  23. ncbi Acinetobacter outbreaks, 1977-2000
    Maria Virginia Villegas
    Cideim Research Center, Cali, Columbia
    Infect Control Hosp Epidemiol 24:284-95. 2003
    ..New approaches and interventional trials are needed to define effective measures for the prevention and control of Acinobacter infections...
  24. ncbi Prevalence of nosocomial infections in hospitals in Norway, 2002 and 2003
    H M Eriksen
    Norwegian Institute of Public Health, P O Box 4404, Nydalen 0403 Oslo, Norway
    J Hosp Infect 60:40-5. 2005
    ..The results can be used to prioritize further infection control measures and more detailed incidence surveillance of nosocomial infections.
  25. ncbi Reduction in nosocomial infection with improved hand hygiene in intensive care units of a tertiary care hospital in Argentina
    Victor D Rosenthal
    Section of Infectious Diseases and Hospital Epidemiology, Colegiales Hospital, Buenos Aires, Argentina
    Am J Infect Control 33:392-7. 2005
    ..We attempted to enhance compliance with hand hygiene by implementing education, training, and performance feedback. We measured nosocomial infections in parallel...
  26. pmc Infection control and the burden of tuberculosis infection and disease in health care workers in china: a cross-sectional study
    Guang Xue He
    National Center for TB control and prevention, China Center for Disease Control and Prevention, Changping District 102206, Beijing, China
    BMC Infect Dis 10:313. 2010
    Hospitals with inadequate infection control are risky environments for the emergence and transmission of tuberculosis (TB)...
  27. ncbi The importance of leadership in preventing healthcare-associated infection: results of a multisite qualitative study
    Sanjay Saint
    Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan 48105, USA
    Infect Control Hosp Epidemiol 31:901-7. 2010
    ..Because preliminary data indicated that hospital leadership played an important role, we sought better to understand which behaviors are exhibited by leaders who are successful at implementing HAI prevention practices in US hospitals...
  28. ncbi A qualitative exploration of reasons for poor hand hygiene among hospital workers: lack of positive role models and of convincing evidence that hand hygiene prevents cross-infection
    V Erasmus
    Department of Public Health, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Infect Control Hosp Epidemiol 30:415-9. 2009
    ..To study potential determinants of hand hygiene compliance among healthcare workers in the hospital setting...
  29. pmc Prioritizing healthcare worker vaccinations on the basis of social network analysis
    Philip M Polgreen
    Department of Internal Medicine, The University of Iowa, Iowa City, Iowa 52242, USA
    Infect Control Hosp Epidemiol 31:893-900. 2010
    ..To use social network analysis to design more effective strategies for vaccinating healthcare workers against influenza...
  30. ncbi Underresourced hospital infection control and prevention programs: penny wise, pound foolish?
    Deverick J Anderson
    Division of Infectious Disease and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Infect Control Hosp Epidemiol 28:767-73. 2007
    To estimate the cost of healthcare-associated infections (HAIs) in a network of 28 community hospitals and to compare this sum to the amount budgeted for infection control programs at each institution and for the entire network.
  31. ncbi Catheter-associated bloodstream infections: looking outside of the ICU
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Infect Control 36:S172.e5-8. 2008
    ..This article is a summary of a talk given at an industry-sponsored conference on CA-BSIs. It summarizes an original article of ours previously published in a peer-reviewed journal...
  32. pmc Electronic sensors for assessing interactions between healthcare workers and patients under airborne precautions
    Jean Christophe Lucet
    Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    PLoS ONE 7:e37893. 2012
    ..We used a Radio Frequency Identification Device (RFID) system to automatically measure HCW-patient interactions...
  33. pmc Infection control rate of irrigation and débridement for periprosthetic joint infection
    Loukas Koyonos
    The Rothman Institute of Orthopaedics, Thomas Jefferson University Hospital, 925 Chestnut Street, 5th Floor, Philadelphia, PA 19107, USA
    Clin Orthop Relat Res 469:3043-8. 2011
    Irrigation and débridement with retention of prosthesis is commonly performed for periprosthetic joint infection. Infection control is reportedly dependent on timing of irrigation and débridement relative to the index procedure.
  34. ncbi Hospital cleaning in the 21st century
    S J Dancer
    Department of Microbiology, Hairmyres Hospital, Eaglesham Road, East Kilbride G75 8RG, UK
    Eur J Clin Microbiol Infect Dis 30:1473-81. 2011
    ..Detergent-based cleaning is cheaper than using disinfectants and much less toxic. Hospital cleaning in the 21st century deserves further investigation for routine and outbreak practices...
  35. pmc A national infection control evaluation of drug-resistant tuberculosis hospitals in South Africa
    J E Farley
    School of Nursing, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Int J Tuberc Lung Dis 16:82-9. 2012
    The importance of infection control (IC) in health care settings with tuberculosis (TB) patients has been highlighted by recent health care-associated outbreaks in South Africa.
  36. pmc Efficacy of infection control interventions in reducing the spread of multidrug-resistant organisms in the hospital setting
    Erika M C D'Agata
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e30170. 2012
    ..However, screening for asymptomatic MDRO colonization among patients who are not receiving antimicrobials is of minimal value in reducing the spread of MDRO...
  37. ncbi Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC)
    Lynne Sehulster
    Division of Healthcare Quality Promotion, National Center for Infectious Diseases
    MMWR Recomm Rep 52:1-42. 2003
    ..The report also suggests a series of performance measurements as a means to evaluate infection-control efforts...
  38. ncbi Waves of trouble: MRSA strain dynamics and assessment of the impact of infection control
    David Wyllie
    John Radcliffe Hospital, Oxford, UK
    J Antimicrob Chemother 66:2685-8. 2011
    ..The biological basis of infectious disease waves, including those of MRSA, is discussed, as are the implications of such waves for the assessment of the impact of infection control measures.
  39. ncbi Cost-effectiveness of universal MRSA screening on admission to surgery
    A Murthy
    Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, 4 rue Gabrielle Perret Gentil, Geneva 14, Switzerland
    Clin Microbiol Infect 16:1747-53. 2010
    ..However, local epidemiology plays a critical role. Settings with a higher prevalence of MRSA colonization may find universal screening cost-effective and, in some cases, cost-saving...
  40. ncbi Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella
    J J Rahal
    Department of Medicine, New York Hospital Medical Center of Queens and Cornell University Medical College, Flushing 11355, USA
    JAMA 280:1233-7. 1998
    ..Resistance to most or all cephalosporin antibiotics in Klebsiella species has developed in many European and North American hospitals during the past 2 decades...
  41. pmc Qualitative real-time schlieren and shadowgraph imaging of human exhaled airflows: an aid to aerosol infection control
    Julian W Tang
    Department of Laboratory Medicine, National University Hospital, Singapore, Singapore
    PLoS ONE 6:e21392. 2011
    ....
  42. ncbi Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control
    Y Carmeli
    Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Clin Microbiol Infect 16:102-11. 2010
    ..This unpreparedness also affects the treatment of individual patients and infection control policies, with dramatic scarcities of both therapeutic options and infection control measures...
  43. pmc Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplasty
    Christopher R Gooding
    Division of Lower Limb Reconstruction and Oncology, Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada
    Clin Orthop Relat Res 469:985-93. 2011
    ..The PROSTALAC knee spacer is an antibiotic-loaded cement articulating spacer that allows some movement of the knee between stages. Whether motion enhances long-term function is unknown...
  44. pmc What counts? An ethnographic study of infection data reported to a patient safety program
    Mary Dixon-Woods
    Department of Health Sciences, University of Leicester, Leicester, United Kingdom
    Milbank Q 90:548-91. 2012
    ..An opportunity for such a study was presented by a patient safety program requiring intensive care units (ICUs) in England to submit monthly data on central venous catheter bloodstream infections (CVC-BSIs)...
  45. pmc Barriers and motivators affecting tuberculosis infection control practices of Russian health care workers
    W Woith
    Department of Nursing, Mennonite College of Nursing at Illinois State University, Normal, Illinois 61761, USA
    Int J Tuberc Lung Dis 16:1092-6. 2012
    ..Five in-patient and out-patient tuberculosis (TB) care facilities in two regions of Russia...
  46. ncbi Need for improved antimicrobial and infection control stewardship in Vietnamese intensive care units
    M Johansson
    Division of Infectious Diseases, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Trop Med Int Health 16:737-43. 2011
    ..Survey of antibiotic consumption, microbial resistance and hygiene precautions in the intensive care units of three hospitals in northern Vietnam...
  47. pmc Multiple component patient safety intervention in English hospitals: controlled evaluation of second phase
    Amirta Benning
    School of Health and Population Sciences, University of Birmingham, Edgbaston, West Midlands B15 2TT, UK
    BMJ 342:d199. 2011
    ..Setting NHS hospitals in England...
  48. ncbi Infection control--a European research perspective for the next decade
    M Dettenkofer
    Institute of Environmental Medicine and Hospital Epidemiology, University Medical Center Freiburg, Freiburg, Germany
    J Hosp Infect 77:7-10. 2011
    ..infection--state of evidence; surveillance of HAI; methodological challenges and research priorities for infection control and control of HAI: learning from each other in a united Europe...
  49. ncbi Variability in the Hawthorne effect with regard to hand hygiene performance in high- and low-performing inpatient care units
    Erol Kohli
    Dartmouth Institute for Health Policy and Clinical Practice, New Hampshire, USA
    Infect Control Hosp Epidemiol 30:222-5. 2009
    ..OBJECTIVE. To determine the impact of known observers on hand hygiene performance in inpatient care units with differing baseline levels of hand hygiene compliance...
  50. pmc Automated detection of infectious disease outbreaks in hospitals: a retrospective cohort study
    Susan S Huang
    Division of Infectious Diseases and Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, California, United States of America
    PLoS Med 7:e1000238. 2010
    ..Ideally, outbreak detection programs should evaluate many pathogens, using a wide array of data sources...
  51. pmc Introduction of an electronic monitoring system for monitoring compliance with Moments 1 and 4 of the WHO "My 5 Moments for Hand Hygiene" methodology
    Vincent C C Cheng
    Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, China
    BMC Infect Dis 11:151. 2011
    MedSense is an electronic hand hygiene compliance monitoring system that provides Infection Control Practitioners with continuous access to hand hygiene compliance information by monitoring Moments 1 and 4 of the WHO "My 5 Moments for ..
  52. pmc Mathematical modeling of the effectiveness of facemasks in reducing the spread of novel influenza A (H1N1)
    Samantha M Tracht
    Energy and Infrastructure Analysis Group, Decisions Applications Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
    PLoS ONE 5:e9018. 2010
    ..We can conclude from our model that, if worn properly, facemasks are an effective intervention strategy in reducing the spread of pandemic (H1N1) 2009...
  53. ncbi Framework for the design and operation of high-level isolation units: consensus of the European Network of Infectious Diseases
    Barbara Bannister
    Department of Infectious Diseases, Royal Free Hospital, London, UK
    Lancet Infect Dis 9:45-56. 2009
    Patients with highly infectious diseases require safe, secure, high-quality medical care with high-level infection control, which may be most effectively delivered by specially trained staff in the setting of a high-level isolation unit (..
  54. ncbi Surveillance of surgical site infections by surgeons: biased underreporting or useful epidemiological data?
    R Rosenthal
    Department of Surgery, Basel University Hospital, Switzerland
    J Hosp Infect 75:178-82. 2010
    ..to compare prospective in-hospital SSI surveillance (I) by the surgical staff and (II) additionally by an infection control team (ICT)...
  55. ncbi Control of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a children's hospital by changing antimicrobial agent usage policy
    Jina Lee
    Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
    J Antimicrob Chemother 60:629-37. 2007
    ....
  56. pmc How to assess the relative importance of different colonization routes of pathogens within hospital settings
    Inti Pelupessy
    Department of Mathematics, University of Utrecht, Budapestlaan 6, 3584 CD Utrecht, The Netherlands
    Proc Natl Acad Sci U S A 99:5601-5. 2002
    The emergence of antibiotic resistance among nosocomial pathogens has reemphasized the need for effective infection control strategies...
  57. ncbi Significant reductions in methicillin-resistant Staphylococcus aureus bacteraemia and clinical isolates associated with a multisite, hand hygiene culture-change program and subsequent successful statewide roll-out
    M Lindsay Grayson
    Infectious Diseases and Clinical Epidemiology Department, Austin Health, Melbourne, Victoria, Australia
    Med J Aust 188:633-40. 2008
    ..To assess the efficacy of a multimodal, centrally coordinated, multisite hand hygiene culture-change program (HHCCP) for reducing rates of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia and disease in Victorian hospitals...
  58. pmc Staffing and structure of infection prevention and control programs
    Patricia W Stone
    Columbia University School of Nursing, 617 W 168th Street, NewYork, NY 10032, USA
    Am J Infect Control 37:351-7. 2009
    ..The nature of infection prevention and control is changing; however, little is known about current staffing and structure of infection prevention and control programs...
  59. ncbi Impact of routine intensive care unit surveillance cultures and resultant barrier precautions on hospital-wide methicillin-resistant Staphylococcus aureus bacteremia
    Susan S Huang
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Clin Infect Dis 43:971-8. 2006
    ..To our knowledge, the relative impact of these interventions has not previously been ascertained...
  60. ncbi Chlorhexidine: expanding the armamentarium for infection control and prevention
    Aaron M Milstone
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Clin Infect Dis 46:274-81. 2008
    ..We review some of the many infection control applications of chlorhexidine in the battle against HAI, such as general skin cleansing, skin decolonization,..
  61. ncbi Transfer of vancomycin-resistant enterococci via health care worker hands
    Amy N Duckro
    Department of Internal Medicine, Section of Infectious Diseases, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Intern Med 165:302-7. 2005
    ..We sought to determine the frequency of VRE transmission from sites in the environment or on patients' intact skin to clean environmental or skin sites via contaminated hands of HCWs during routine care...
  62. pmc The dynamics of risk perceptions and precautionary behavior in response to 2009 (H1N1) pandemic influenza
    Yoko Ibuka
    Department of Epidemiology and Public Health, Yale School of Medicine, 60 College Street, New Haven, CT 06520, USA
    BMC Infect Dis 10:296. 2010
    ..We assessed temporal changes and geographical differences in risk perceptions and precautionary behaviors in response to H1N1 influenza...
  63. ncbi Laboratory tools and strategies for methicillin-resistant Staphylococcus aureus screening, surveillance and typing: state of the art and unmet needs
    M J Struelens
    Department of Clinical Microbiology, Universite Libre de Bruxelles Hopital Erasme, Brussels, Belgium
    Clin Microbiol Infect 15:112-9. 2009
    ..Further refinement of genotyping methods and international harmonization of surveillance and typing schemes must be achieved to facilitate global MRSA control...
  64. ncbi Spread of methicillin-resistant Staphylococcus aureus in a neonatal intensive unit associated with understaffing, overcrowding and mixing of patients
    B M Andersen
    Department of Hospital Infection, Ulleval University Hospital, Oslo, Norway
    J Hosp Infect 50:18-24. 2002
    ..The NICU and the delivery suite were closed for one week for disinfection and screening. The outbreak ended after 34 days. Since then, two years later, no further cases have been detected in the NICU or the delivery suite...
  65. ncbi Guidelines for the control and prevention of meticillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities
    J E Coia
    Department of Bacteriology, Glasgow Royal Infirmary, Glasgow, UK
    J Hosp Infect 63:S1-44. 2006
    ..The general principles of infection control should be adopted for patients with MRSA, including patient isolation and the appropriate cleaning and ..
  66. ncbi Impact of ring wearing on hand contamination and comparison of hand hygiene agents in a hospital
    William E Trick
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Clin Infect Dis 36:1383-90. 2003
    ..9; 95% CI, 0.5-1.6). Ring wearing increased the frequency of hand contamination with potential nosocomial pathogens. Use of an alcohol-based hand rub resulted in significantly less frequent hand contamination...
  67. ncbi Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two-centre study
    Jorge A Cepeda
    Department of Clinical Microbiology, University College London Hospitals, London W1T 4 JF, UK
    Lancet 365:295-304. 2005
    ..We aimed to assess the effectiveness of moving versus not moving infected or colonised patients in intensive-care units to prevent transmission of MRSA...
  68. ncbi Reduction in the rate of methicillin-resistant Staphylococcus aureus acquisition in surgical wards by rapid screening for colonization: a prospective, cross-over study
    Katherine Hardy
    West Midlands Public Health Laboratory, Heart of England NHS Foundation Trust, Birmingham, UK
    Clin Microbiol Infect 16:333-9. 2010
    ..This result was achieved in a routine surgical service with high bed occupancy and low availability of isolation rooms, making it applicable to the majority of health-care systems worldwide...
  69. ncbi Use of stochastic epidemic modeling to quantify transmission rates of colonization with methicillin-resistant Staphylococcus aureus in an intensive care unit
    Marie Forrester
    School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
    Infect Control Hosp Epidemiol 26:598-606. 2005
    ....
  70. pmc Transmission of drug-susceptible and drug-resistant tuberculosis and the critical importance of airborne infection control in the era of HIV infection and highly active antiretroviral therapy rollouts
    Sheela V Shenoi
    AIDS Program, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut 06510 2483, USA
    Clin Infect Dis 50:S231-7. 2010
    ..New research and resources are required to fully realize the potential benefits of infection control in the era of TB and HIV epidemics.
  71. ncbi Environmental reservoirs of methicillin-resistant Staphylococcus aureus in isolation rooms: correlation with patient isolates and implications for hospital hygiene
    T Sexton
    Department of Infection Control, Beaumont Hospital, Dublin, Ireland
    J Hosp Infect 62:187-94. 2006
    ..More effective and rigorous use of current approaches to cleaning and decontamination is required as well as consideration of newer technologies to eradicate MRSA and other hospital-acquired pathogens...
  72. ncbi Determinants of surgical site infection after breast surgery
    M L Bertin
    Infection Control and Epidemiology, Cleveland Clinic Foundation, OH 44195, USA
    Am J Infect Control 26:61-5. 1998
    ..9% (3 infections for 332 procedures). CONCLUSIONS: Host factors may contribute to SSI in breast procedures. Cefazolin sodium prophylaxis was useful in preventing SSI after breast surgery...
  73. ncbi Tuberculosis control has failed in South Africa--time to reappraise strategy
    Robin Wood
    Desmond Tutu HIV Centre, and Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town
    S Afr Med J 101:111-4. 2011
    ..This better understanding of the major drivers of the TB epidemic allows reasons to be identified for failure of the present strategy. New control strategies can also be identified, that must be accompanied by novel TB control targets...
  74. ncbi Is surveillance for multidrug-resistant enterobacteriaceae an effective infection control strategy in the absence of an outbreak?
    Michael A Gardam
    Infection Prevention and Control Unit, Toronto General Hospital, Toronto, Ontario, Canada M5G 2C4
    J Infect Dis 186:1754-60. 2002
    ..The annual cost of a surveillance program was calculated at Canadian $1,130,184.44. Thus, the routine and costly use of MDRE surveillance and isolation precautions are not warranted in the absence of a clonal outbreak in this population...
  75. ncbi Practices and an assessment of health care workers' perceptions of compliance with infection control knowledge of nosocomial infections
    Mezgebe Berhe
    Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
    Am J Infect Control 33:55-7. 2005
  76. ncbi Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HIPAC/SHEA/APIC/IDSA Hand Hygiene Task Force
    John M Boyce
    Hospital of Saint Raphael, New Haven
    Am J Infect Control 30:S1-46. 2002
    ..Recommendations concerning related issues (e.g., the use of surgical hand antiseptics, hand lotions or creams, and wearing of artificial fingernails) are also included...
  77. ncbi Quality of traditional surveillance for public reporting of nosocomial bloodstream infection rates
    Michael Y Lin
    Section of Infectious Diseases, Department of Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    JAMA 304:2035-41. 2010
    ..However, such comparisons are valid only if surveillance is performed consistently across institutions...
  78. ncbi Contact isolation in surgical patients: a barrier to care?
    Heather L Evans
    Department of Surgery, UVA Health System, Charlottesville, VA 22908, USA
    Surgery 134:180-8. 2003
    ..Contact isolation is commonly used to prevent transmission of resistant organisms. We hypothesized that contact isolation negatively impacts the amount of direct patient care...
  79. ncbi A survey of doctors' and nurses' knowledge, attitudes and compliance with infection control guidelines in Birmingham teaching hospitals
    A D Stein
    School of Medicine, The University of Birmingham, Birmingham, UK
    J Hosp Infect 54:68-73. 2003
    This study investigated knowledge about infection control amongst doctors and nurses through a cross-sectional survey conducted between March and May 2001 in three Birmingham, UK teaching hospitals...
  80. ncbi Vancomycin-resistant Staphylococcus aureus in the United States, 2002-2006
    Dawn M Sievert
    Michigan Department of Community Health, Lansing, USA
    Clin Infect Dis 46:668-74. 2008
    ....
  81. ncbi The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection
    Sheldon P Stone
    Academic Department of Geriatric Medicine, Royal Free and University College Medical School, London, UK
    Lancet Infect Dis 7:282-8. 2007
    The quality of research in hospital epidemiology (infection control) must be improved to be robust enough to influence policy and practice...
  82. ncbi Statistical analysis and application of quasi experiments to antimicrobial resistance intervention studies
    Michelle Shardell
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 45:901-7. 2007
    ..An example of a hospital-based intervention to reduce methicillin-resistant Staphylococcus aureus infection rates and reduce overall length of stay is used to explore these methods...
  83. ncbi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
    ....
  84. ncbi Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting
    John M Boyce
    Hospital of St Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Infect Control Hosp Epidemiol 29:723-9. 2008
    ..To determine whether hydrogen peroxide vapor (HPV) decontamination can reduce environmental contamination with and nosocomial transmission of Clostridium difficile...
  85. ncbi Evidence that hospital hygiene is important in the control of methicillin-resistant Staphylococcus aureus
    A Rampling
    Public Health Laboratory, Pathology Department, Dorset County Hospital, Williams Avenue, Dorchester, DT1 2JY, UK
    J Hosp Infect 49:109-16. 2001
    ..From January 1998 to September 1999, despite standard infection control measures (emphasis on hand hygiene, isolation of affected patients and staggered closure and cleaning of ..
  86. ncbi Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005
    Paul A Jensen
    Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Atlanta, GA 30333, USA
    MMWR Recomm Rep 54:1-141. 2005
    ..an increase in the prevalence of TB disease and human immunodeficiency virus (HIV) coinfection, 3) lapses in infection control practices, 4) delays in the diagnosis and treatment of persons with infectious TB disease, and 5) the ..
  87. ncbi Nonhospital health care-associated hepatitis B and C virus transmission: United States, 1998-2008
    Nicola D Thompson
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Ann Intern Med 150:33-9. 2009
    ..transmission through failure of health care personnel to adhere to fundamental principles of infection control and aseptic technique (for example, reuse of syringes or lancing devices)...
  88. ncbi Do physicians examine patients in contact isolation less frequently? A brief report
    Sanjay Saint
    Ann Arbor Department of Veterans Affairs Medical Center, USA
    Am J Infect Control 31:354-6. 2003
    ..We assessed whether patients who are hospitalized and placed under contact precautions are examined less often by second- and third-year medical residents (ie, senior medical residents), and attending physicians during morning rounds...
  89. pmc Antimicrobial stewardship programs in health care systems
    Conan MacDougall
    Department of Pharmacy, School of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298, USA
    Clin Microbiol Rev 18:638-56. 2005
    ..teams composed of infectious diseases physicians, clinical pharmacists, clinical microbiologists, and infection control practitioners and should be actively supported by hospital administrators...
  90. ncbi Parenteral nutrition as a risk factor for central venous catheter-related infection
    Mariur G Beghetto
    Nursing Division, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos 2350, 90035 003 Porto Alegre, RS, Brazil
    JPEN J Parenter Enteral Nutr 29:367-73. 2005
    ..The aim of this study was to evaluate PN as a risk factor for central venous catheter-related infection in nonselected adult patients in a general university hospital...
  91. ncbi Infection control as a major World Health Organization priority for developing countries
    D Pittet
    Infection Control Programme, University of Geneva Hospitals, Geneva, Switzerland
    J Hosp Infect 68:285-92. 2008
    ..long-term disability for hundreds of millions of patients, and lead to major cost savings through the improvement of basic infection control measures in any healthcare setting, regardless of resources available or level of development.
  92. ncbi The Lowbury lecture: behaviour in infection control
    D Pittet
    Infection Control Programme, University of Geneva Hospitals, Geneva, Switzerland
    J Hosp Infect 58:1-13. 2004
    ..Improving practices frequently implies modifying healthcare workers' behaviour, a key challenge of today's infection control. To improve healthcare workers' compliance with practices, infection control should learn from the ..
  93. pmc Computer algorithms to detect bloodstream infections
    William E Trick
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Emerg Infect Dis 10:1612-20. 2004
    ..by using five methods: retrospective, manual record review by investigators; prospective, manual review by infection control professionals; positive blood culture plus manual CVC determination; computer algorithms; and computer ..
  94. ncbi Environmental controls in operating theatres
    S Dharan
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, Switzerland
    J Hosp Infect 51:79-84. 2002
    ..Environmental bacterial sampling in operating theatres should be limited to investigation of epidemics, validation of protocols, or changes made in materials which could influence the microbial content...
  95. pmc Impact of enhanced infection control at 2 neonatal intensive care units in the Philippines
    Christopher J Gill
    Center for International Health and Development, Department of International Health, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Clin Infect Dis 48:13-21. 2009
    ..The growing burden of neonatal mortality associated with hospital-acquired neonatal sepsis in the developing world creates an urgent need for cost-effective infection-control measures in resource-limited settings...
  96. ncbi Undiagnosed tuberculosis among HIV clinic attendees: association with antiretroviral therapy and implications for intensified case finding, isoniazid preventive therapy, and infection control
    Tendesayi Kufa
    Aurum Institute for Health Research, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 60:e22-8. 2012
    ..We describe factors associated with undiagnosed TB among HIV-infected patients attending an HIV clinic in South Africa and discuss implications for the 3 Is...
  97. ncbi ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients
    E Tacconelli
    Division of Infectious Diseases, Department of Internal Medicine I, Tubingen University Hospital, Tubingen, Germany
    Clin Microbiol Infect 20:1-55. 2014
    ..The level of evidence for and strength of each recommendation, were defined according to the GRADE approach. ..
  98. ncbi Hospitals in Europe Link for Infection Control through Surveillance (HELICS). Inter-country comparison of rates of surgical site infection--opportunities and limitations
    J Wilson
    Healthcare Associated Infection and Antimicrobial Resistance Department, Centre for Infection, Health Protection Agency, London, UK
    J Hosp Infect 65:165-70. 2007
    ..The Hospitals in Europe Link for Infection Control through Surveillance (HELICS) has provided a standardised approach to surveillance of HCAI and formed a '..
  99. ncbi Airborne hydrogen peroxide for disinfection of the hospital environment and infection control: a systematic review
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Hosp Infect 78:171-7. 2011
    We reviewed the effectiveness of airborne hydrogen peroxide as an environmental disinfectant and infection control measure in clinical settings. Systematic review identified ten studies as eligible for inclusion...
  100. ncbi Preventing nosocomial infections: improving compliance with standard precautions in an Indonesian teaching hospital
    D O Duerink
    Department of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands
    J Hosp Infect 64:36-43. 2006
    ..Compliance with safe handling of needles improved slightly due to introduction of the one-handed method for safe recapping of used needles...
  101. ncbi The role of the champion in infection prevention: results from a multisite qualitative study
    L J Damschroder
    VA Ann Arbor HSR and D Center of Excellence, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Qual Saf Health Care 18:434-40. 2009
    ..We explored the types and numbers of champions who lead efforts to implement best practices to prevent hospital-acquired infection in US hospitals...

Research Grants66

  1. Device use in Nursing Homes: Reducing Risk of Infection
    Lona Mody; Fiscal Year: 2007
    ..research interest is epidemiology of nosocomial infections in long-term care and developing effective infection control strategies targeted at reducing these infections with a goal to reduce antimicrobial usage, antimicrobial ..
  2. Outcomes of ICU Working Conditions
    Patricia Stone; Fiscal Year: 2003
    ..In addition, obtaining NNIS and Medicare data creates an opportunity to explore the sensitivity and specificity of identifying NI through claims data. ..
  3. Stopping URIs and FLU in the Family: the Stuffy Trial
    Elaine Larson; Fiscal Year: 2008
    ....
  4. Impact of Hand Hygiene Guideline on Infections and Costs
    Elaine Larson; Fiscal Year: 2005
    ..abstract_text> ..
  5. HOME HYGIENE INTERVENTION
    Elaine Larson; Fiscal Year: 2002
    ..Logistic regression, Liang-Zeger regression, and Chi Square analyses will be used to test differences in rates of transmission of symptoms and changes in quantity, types and resistance patterns of microbial flora of the hands. ..
  6. Staff Hand Hygiene and Nosocomial Infections in Neonates
    Elaine Larson; Fiscal Year: 2003
    ....
  7. Interdisciplinary Research:Antimicrobial Resistance(RMI)
    Elaine Larson; Fiscal Year: 2006
    ..In the final year, plans for a sustainable Consortium on antimicrobial resistance will be formalized. [unreadable] [unreadable]..
  8. Catheter Dwell Time and Risk of Bloodstream Infections in Hospitalized Neonates
    Aaron M Milstone; Fiscal Year: 2011
    ..This project will help to develop evidence-based strategies to prevent bloodstream infections among vulnerable infants hospitalized in the neonatal intensive care unit. ..
  9. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    ..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
  10. NETWORK OF PEDIATRIC PHARMACOLOGY RESEARCH UNITS
    Michael Brady; Fiscal Year: 2003
    ..This would enhance the pace of pediatric drug development, increase the number of trained pediatric pharmacologists available, and improve both the amount and quality of pediatric pharmacology research produced. ..
  11. Prevention of Healthcare-Associated Drug-Resistant GNR
    Lisa Maragakis; Fiscal Year: 2006
    ..disease fellow at the Johns Hopkins University whose research is in the area of hospital epidemiology and infection control under the mentorship of Dr. Irish Perl. Through this award, Dr...
  12. A community-level RCT of expedited partner treatment for gonorrhea and chlamydia
    Matthew R Golden; Fiscal Year: 2010
    ..abstract_text> ..
  13. Study design importance in analyzing emerging pathogens
    Anthony Harris; Fiscal Year: 2005
    ..The second aim will be done by combining epidemiological relatedness and molecular relatedness through pulse-field gel electrophoresis of ESBL cultures to quantify the importance of patient to patient transmission. ..
  14. Hospital-Acquired Infections in the Elderly
    Keith Kaye; Fiscal Year: 2008
    ..Methods: The project will utilize 10 study hospitals and an infection control infrastructure that includes 3 physician epidemiologists and over 20 infection control practitioners...
  15. The Balanced Budget Act of 1997 and Home Care for Cancer
    Meredith Kilgore; Fiscal Year: 2006
    ..Data generated from this study can be used to guide federal decision makers in formulating policies related to home health services for older cancer patients. ..
  16. New Nosocomial Interventions to Decrease Antimicrobial Resistance Transmission
    Anthony Harris; Fiscal Year: 2008
    ..modeling and quasi- experimental study design that will be able to scientifically study important infection control interventions and advance our understanding of how antimicrobial resistant bacterial pathogens are most ..
  17. Novel Application of Infection Control Strategies to Limit Transmission of ESBL'S
    Ebbing Lautenbach; Fiscal Year: 2008
    ..However, the ability of infection control strategies to limit ESBL-EK transmission has been largely untested and remains controversial...
  18. Bloodborne Pathogen Risk in Home Healthcare Workers
    Robyn Gershon; Fiscal Year: 2007
    ..This study will improve our understanding of the risks facing home health care workers and allow us to focus our risk management energies and resources appropriately. ..
  19. SIV Cardiomyopathy: Pathogenesis and Prevention
    Richard Shannon; Fiscal Year: 2007
    ..The identified mechanisms will serve as a prerequisite for exploring specific strategies to prevent cardiac involvement in chronic SIV infection. ..
  20. Epidemiology of multidrug-resistant tuberculosis in Peru
    Mercedes Becerra; Fiscal Year: 2008
    ..tuberculosis strains. Results will serve to guide basic research in tuberculosis diagnostics and therapeutics. ..
  21. In-Home Prevention of SA risks in Native Teen Families
    John T Walkup; Fiscal Year: 2010
    ....
  22. Mathematical Modeling of the Superspreaders of Antibiotic-Resistante Bacteria
    Shigui Ruan; Fiscal Year: 2010
    ..The proposed work will lead to a better understanding of the factors which contribute to the spread of ARB, and will allow the development and implementation of effective public health policies. ..
  23. co-Trimoxazole in Zambian Infants (TZI)
    CHRISTOPHER GILL; Fiscal Year: 2007
    ..abstract_text> ..
  24. DOT-HAART for HIV-Infected South African Adults
    Richard Chaisson; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  25. A Web-based Conference on Evidence Based Practice for Rural Hospitals
    Kathleen Oman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  26. A Trial of Zinc and Micronutrients in Tanzanian Children
    Christopher P Duggan; Fiscal Year: 2010
    ..As experts in the fields of nutrition, pediatrics, epidemiology and maternal and child health, our team is committed to further evaluating the possible role of micronutrients in improving child health. ..
  27. Prevalence, risk factors and consequences of complex M. Tuberculosis infections
    Theodore Cohen; Fiscal Year: 2010
    ..The overall goal of this study is to learn more about the natural history of TB and to use this knowledge to improve the health of individuals and their communities. ..
  28. Aging, Insulin Resistance, and Dilated Cardiomyopathy
    Richard Shannon; Fiscal Year: 2008
    ..Finally, we will determine if overcoming myocardial insulin resistance in the aging and failing heart will prevent the progression of dilated cardiomyopathy. ..
  29. INCIDENT REPORTING IN NURSING HOMES
    Nicholas Castle; Fiscal Year: 2008
    ..This information will further our development of a standardized incident reporting mechanism recommended by the Institute of Medicine and others. [unreadable] [unreadable] [unreadable]..
  30. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Saiman; Fiscal Year: 2009
    ..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
  31. Quinolone resistant E coli in long term care facilities
    Ebbing Lautenbach; Fiscal Year: 2009
    ..abstract_text> ..
  32. Risk of Blood Borne Transmission of CJD
    Shimian Zou; Fiscal Year: 2008
    ..Publishanddisseminateresultsof thestudy. ..
  33. The Influence of Staff Turnover on Quality
    Nicholas Castle; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  34. Clinical Impact of Quinolone-Resistant E.coli carriage
    Ebbing Lautenbach; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  35. Molecular approaches for understanding TB dynamics
    Theodore Cohen; Fiscal Year: 2008
    ..It is our hope that better analytic techniques will allow for more accurate assessments of treatment and prevention. [unreadable] [unreadable]..
  36. Infection Risk of Urinary Collection Strategies
    Sanjay Saint; Fiscal Year: 2006
    ..Since approximately 40% of elderly Americans will enter a nursing home at some point, identification of those at risk of infection could have considerable health, quality of life, and economic consequences. ..
  37. Ethical Challenges in Lead Poisoning Prevention Research
    Nancy Kass; Fiscal Year: 2005
    ..The investigators hypothesize that our approach can produce models for education of diverse communities and EH scientists. ..
  38. IgA-Antigen Uptake by Peyer's Patch M cells
    NICHOLAS MANTIS; Fiscal Year: 2003
    ..The three year KO1 award will provide the applicant with-additional research training and career skills that will greatly facilitate his transition to becoming a successful independent research investigator. ..
  39. Mentored Patient-Oriented Research Career Development Aw
    Richard Rothman; Fiscal Year: 2004
    ..Findings from this research will provide valuable information that can be used to guide and improve evaluation and management of the growing number of febrile IDUs. ..
  40. BLOODBORNE EXPOSURE MANAGEMENT
    Robyn Gershon; Fiscal Year: 2001
    ..This study will identify barriers to appropriate implementation of the Guidelines and allow us to focus our energies and resources on specific improvements in order to minimize the risk of infection to exposed employees. ..
  41. ENHANCING MUCOSAL IMMUNE RESPONSES BY MICROENCAPSULATION
    Paul Offit; Fiscal Year: 2005
    ..The availability of microencapsulated virus provides a unique opportunity to understand the relationship between APC and protective mucosal immune responses. ..
  42. QUINOLONE RESISTANCE IN NOSOCOMIAL URINARY INFECTIONS
    Ebbing Lautenbach; Fiscal Year: 2004
    ....
  43. CHRONIC COCAINE EFFECTS ON NORMAL AND DISEASED HEARTS
    Richard Shannon; Fiscal Year: 2006
    ..Finally, we will determine the role of altered SNS activity, altered nitric oxide activity, and increased cytokine expression, in the mechanisms of chronic cocaine toxicity. ..
  44. Health Information Technology Value in Rural Hospitals
    Marcia Ward; Fiscal Year: 2006
    ..The toolkits will facilitate rural hospitals' ability to utilize current and emerging evidence to guide HIT investment and implementation decisions that fit their particular healthcare environment. ..
  45. GENE EXPRESSION IN BRUCELLA-INFECTED MACROPHAGES
    Yongqun He; Fiscal Year: 2005
    ..abstract_text> ..
  46. WHO MULTICENTER GROWTH REFERENCE STUDY: U.S. SITE
    Kathryn Dewey; Fiscal Year: 2002
    ..The data will be pooled by WHO to create a new growth reference, applicable to all infants and children internationally. ..
  47. Physical Activity, Learning Styles and Health Literacy
    Julie Gazmararian; Fiscal Year: 2006
    ..g., custodial, faculty), and an advisory panel of nationally renowned public health and learning theory professionals. ..
  48. Genetic Virulence Markers in Respiratory Syncytial Virus
    RICHARD MARTINELLO; Fiscal Year: 2006
    ..A committee consisting of established basic scientists, clinical researchers and hospital epidemiology mentors has been established to provide scientific guidance and training oversight. ..
  49. BBP EXPOSURE AND RISK FACTORS IN NON-HOSPITAL BASED HCWS
    Robyn Gershon; Fiscal Year: 2002
    ..This study will improve our understanding of the risks facing non-hospital HCWs and allow us to focus our energies and resources appropriately. ..
  50. Innovative HCW Training: Infectious Disease Risk
    Robyn Gershon; Fiscal Year: 2002
    ..The results of this study may have important implications for effective health and safety training for nurses. ..
  51. Evalulation of Echinacea in a Human Rhinovirus Challenge
    Ronald Turner; Fiscal Year: 2003
    ....
  52. Aminocaproic Acid and Bleeding in Spinal Surgery
    Sean Berenholtz; Fiscal Year: 2006
    ..These projects and the career development plan described will build a foundation for a successful career as an independent investigator. ..
  53. IMMUNOGENETIC MECHANISMS OF VACCINE RESPONSE
    Gregory A Poland; Fiscal Year: 2010
    ..The knowledge gained from these studies will enable us to design new strategies and new vaccines to protect human health against viral diseases. ..
  54. Discharge Planning and Telehealth for Post CABG Elders
    Ruth Kleinpell; Fiscal Year: 2009
    ....
  55. REMOTE SENSING AND GIS FOR SCHISTOSOMIASIS CONTROL
    Robert Spear; Fiscal Year: 2002
    ..Subsequently, efforts will be made to make the classification more precise by supplementing these data with ecological and landscape data and to evaluate alternative remotely sensed data for their ability to predict risk areas. ..
  56. Local Strategies for Schistosomiasis Control
    Robert Spear; Fiscal Year: 2006
    ....
  57. Neurocognitive Consequences of HIV/AIDS in South India
    Timothy Flanigan; Fiscal Year: 2004
    ..The developmental grant will yield significant advances in the understanding of brain disorders associated with HIV. ..
  58. ADULT THERAPEUTIC CLINICAL TRIALS PROGRAM FOR HIV/AIDS
    Timothy Flanigan; Fiscal Year: 2006
    ..This clinical site will be able to contribute to the agenda of long term viral suppression in all compartments utilizing combination therapies, particularly among women and hard to reach populations. ..
  59. Vaccine induced resistance against E. granulosus in dogs
    Wenbao Zhang; Fiscal Year: 2007
    ..granulosus infection by vaccination with the recombinant proteins. We will test humoral and cellular responses generated during vaccination to determine possible correlations of the immune parameters with protection. ..
  60. Planning Grant fo rthe Borwn Institute for Clinical and Translational Science
    Timothy Flanigan; Fiscal Year: 2006
    ..The innovative structure of BICTS provides a new paradigm for synergistic, transdisciplinary clinical research and training for the 21st century. [unreadable] [unreadable] [unreadable]..
  61. The Influence of Heart Failure Self-Care Behavior on Cardiac Performance
    Christopher Lee; Fiscal Year: 2008
    ..This study will help determine if the day-to-day self-care behaviors of heart failure patients can influence how the heart functions. [unreadable] [unreadable] [unreadable]..
  62. INTERDISCIPLINARY TRAINING IN HIV/AIDS EPIDEMIOLOGY
    Roger Detels; Fiscal Year: 2005
    ..Trainees will be expected to publish at least one paper from their dissertation. Special efforts will be made to recruit qualified candidates from underrepresented minority groups. ..
  63. DIRECTLY OBSERVED HAART FOR ACTIVE SUBSTANCE ABUSERS
    Timothy Flanigan; Fiscal Year: 2003
    ..The ACASI questionnaire will be administered and sera collected for laboratory assays at baseline, 1,3,6,9,12,15,18,21, and 24 months. ..
  64. Novel TB Prevention Regimens for HIV-Infected Adults
    Richard Chaisson; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..