environmental microbiology

Summary

Summary: The study of microorganisms living in a variety of environments (air, soil, water, etc.) and their pathogenic relationship to other organisms including man.

Top Publications

  1. ncbi A molecular view of microbial diversity and the biosphere
    N R Pace
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    Science 276:734-40. 1997
  2. pmc Microbial diversity in the deep sea and the underexplored "rare biosphere"
    Mitchell L Sogin
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, 7 MBL Street, Woods Hole, MA 02543, USA
    Proc Natl Acad Sci U S A 103:12115-20. 2006
  3. pmc Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness
    Patrick D Schloss
    Department of Plant Pathology, University of Wisconsin Madison, 1630 Linden Dr, Madison, WI 53706, USA
    Appl Environ Microbiol 71:1501-6. 2005
  4. ncbi Community structure and metabolism through reconstruction of microbial genomes from the environment
    Gene W Tyson
    Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA
    Nature 428:37-43. 2004
  5. pmc Metagenomics: application of genomics to uncultured microorganisms
    Jo Handelsman
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    Microbiol Mol Biol Rev 68:669-85. 2004
  6. pmc Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia
    Paul D R Johnson
    Infectious Disease Department, Austin Health, Melbourne, Victoria, Australia
    Emerg Infect Dis 13:1653-60. 2007
  7. pmc BIPES, a cost-effective high-throughput method for assessing microbial diversity
    Hong Wei Zhou
    Department of Environmental Health, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, Guangdong, China
    ISME J 5:741-9. 2011
  8. pmc A major role for mammals in the ecology of Mycobacterium ulcerans
    Janet A M Fyfe
    Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia
    PLoS Negl Trop Dis 4:e791. 2010
  9. pmc Characterization of environmental sources of the human and animal pathogen Cryptococcus gattii in British Columbia, Canada, and the Pacific Northwest of the United States
    Sarah E Kidd
    School of Occupational and Environmental Hygiene, 364 2206 East Mall, Vancouver, University of British Columbia V6T 1Z3, Canada
    Appl Environ Microbiol 73:1433-43. 2007
  10. ncbi Nitrogenase gene diversity and microbial community structure: a cross-system comparison
    Jonathan P Zehr
    Department of Ocean Sciences, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Environ Microbiol 5:539-54. 2003

Detail Information

Publications287 found, 100 shown here

  1. ncbi A molecular view of microbial diversity and the biosphere
    N R Pace
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    Science 276:734-40. 1997
    ....
  2. pmc Microbial diversity in the deep sea and the underexplored "rare biosphere"
    Mitchell L Sogin
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, 7 MBL Street, Woods Hole, MA 02543, USA
    Proc Natl Acad Sci U S A 103:12115-20. 2006
    ..Members of the rare biosphere are highly divergent from each other and, at different times in earth's history, may have had a profound impact on shaping planetary processes...
  3. pmc Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness
    Patrick D Schloss
    Department of Plant Pathology, University of Wisconsin Madison, 1630 Linden Dr, Madison, WI 53706, USA
    Appl Environ Microbiol 71:1501-6. 2005
    ..We anticipate that an equivalent extent of sampling for soil would require sampling more than 10,000 sequences, almost 100 times the size of typical sequence collections obtained from soil...
  4. ncbi Community structure and metabolism through reconstruction of microbial genomes from the environment
    Gene W Tyson
    Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA
    Nature 428:37-43. 2004
    ..Analysis of the gene complement for each organism revealed the pathways for carbon and nitrogen fixation and energy generation, and provided insights into survival strategies in an extreme environment...
  5. pmc Metagenomics: application of genomics to uncultured microorganisms
    Jo Handelsman
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    Microbiol Mol Biol Rev 68:669-85. 2004
    ..The application of metagenomic sequence information will facilitate the design of better culturing strategies to link genomic analysis with pure culture studies...
  6. pmc Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia
    Paul D R Johnson
    Infectious Disease Department, Austin Health, Melbourne, Victoria, Australia
    Emerg Infect Dis 13:1653-60. 2007
    ..Forty-eight pools (5 species) were positive for insertion sequence IS2404 (maximum likelihood estimate 4.3/1,000), and we confirmed the presence of M. ulcerans in a subset of pools by detection of 3 additional PCR targets...
  7. pmc BIPES, a cost-effective high-throughput method for assessing microbial diversity
    Hong Wei Zhou
    Department of Environmental Health, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, Guangdong, China
    ISME J 5:741-9. 2011
    ..As a laborsaving and cost-effective method, BIPES can be routinely used to analyze the microbial ecology of both environmental and human microbiomes...
  8. pmc A major role for mammals in the ecology of Mycobacterium ulcerans
    Janet A M Fyfe
    Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia
    PLoS Negl Trop Dis 4:e791. 2010
    ..The purpose of this study was to investigate the environmental distribution of M. ulcerans in south-eastern Australia...
  9. pmc Characterization of environmental sources of the human and animal pathogen Cryptococcus gattii in British Columbia, Canada, and the Pacific Northwest of the United States
    Sarah E Kidd
    School of Occupational and Environmental Hygiene, 364 2206 East Mall, Vancouver, University of British Columbia V6T 1Z3, Canada
    Appl Environ Microbiol 73:1433-43. 2007
    ..Our findings indicate extensive colonization by C. gattii within British Columbia and highlight an expansion of the ecological niche of this pathogen...
  10. ncbi Nitrogenase gene diversity and microbial community structure: a cross-system comparison
    Jonathan P Zehr
    Department of Ocean Sciences, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Environ Microbiol 5:539-54. 2003
    ..The broad analysis of nitrogenase genes provides a basis for developing molecular assays and bioinformatics approaches for the study of nitrogen fixation in the environment...
  11. ncbi Environmental detection of octahaem cytochrome c hydroxylamine/hydrazine oxidoreductase genes of aerobic and anaerobic ammonium-oxidizing bacteria
    Markus C Schmid
    Department of Microbiology, IWWR, Radboud University Nijmegen, Nijmegen, The Netherlands
    Environ Microbiol 10:3140-9. 2008
    ..We propose that OCC protein-encoding genes are suitable targets for molecular ecological studies on both aerobic and anaerobic ammonium-oxidizing bacteria...
  12. pmc Ecology and transmission of Buruli ulcer disease: a systematic review
    Richard W Merritt
    Department of Entomology, Michigan State University, East Lansing, Michigan, USA
    PLoS Negl Trop Dis 4:e911. 2010
    ..The application of these criteria to the transmission of M. ulcerans presents a significant challenge...
  13. pmc Measuring the effect of enhanced cleaning in a UK hospital: a prospective cross-over study
    Stephanie J Dancer
    Department of Microbiology, Hairmyres Hospital, East Kilbride, UK
    BMC Med 7:28. 2009
    ..This study aimed to evaluate the potential impact of one additional cleaner by using microbiological standards based on aerobic colony counts and the presence of Staphylococcus aureus including meticillin-resistant S. aureus...
  14. ncbi Environmental microbiology through the lens of high-throughput DNA sequencing: synopsis of current platforms and bioinformatics approaches
    Ramiro Logares
    Institute of Marine Sciences, CSIC, Barcelona ES 08003, Spain
    J Microbiol Methods 91:106-13. 2012
    The incursion of High-Throughput Sequencing (HTS) in environmental microbiology brings unique opportunities and challenges...
  15. pmc Development of a recA gene-based identification approach for the entire Burkholderia genus
    George W Payne
    Cardiff School of Biosciences, Main Building, Museum Avenue, PO Box 915, Cardiff University, Cardiff, Wales CF10 3TL, United Kingdom
    Appl Environ Microbiol 71:3917-27. 2005
    ..cepacia complex strains recovered from clinical infection versus the natural environment, it did facilitate the identification of clonal strain types of B. cepacia, B. stabilis, and B. ambifaria capable of residing in both niches...
  16. ncbi Diverse circovirus-like genome architectures revealed by environmental metagenomics
    Karyna Rosario
    College of Marine Science, University of South Florida, St Petersburg, FL 33701, USA
    J Gen Virol 90:2418-24. 2009
    ..Investigating the complex community of ssDNA viruses in the environment can lead to the discovery of divergent species and help elucidate evolutionary links between ssDNA viruses...
  17. pmc Diversity and seasonal dynamics of bacterial community in indoor environment
    Helena Rintala
    Environmental Health Department, National Public Health Institute, P, O, Box 95, 70701 Kuopio, Finland
    BMC Microbiol 8:56. 2008
    ..The application of molecular methods previously utilised in other environments has resulted in a substantial increase in our awareness of microbial diversity...
  18. ncbi Use of the ITS primers, ITS1F and ITS4, to characterize fungal abundance and diversity in mixed-template samples by qPCR and length heterogeneity analysis
    Daniel K Manter
    USDA ARS, Soil Plant Nutrient Research Unit, Ft Collins, CO, United States
    J Microbiol Methods 71:7-14. 2007
    ..Variability associated with the individual steps of the LH-qPCR analysis was also determined from environmental samples...
  19. ncbi Molecular epidemiology of clinical and environmental isolates of the Cryptococcus neoformans species complex reveals a high genetic diversity and the presence of the molecular type VGII mating type a in Colombia
    Patricia Escandon
    Grupo de Microbiologia, Instituto Nacional de Salud, Bogota, Colombia
    FEMS Yeast Res 6:625-35. 2006
    ..The data presented form part of the Colombian contribution to the ongoing global survey of the C. neoformans species complex...
  20. ncbi Experimental tests of the bacterial distance-decay relationship
    Thomas Bell
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK
    ISME J 4:1357-65. 2010
    ....
  21. pmc Simultaneous analysis of microbial identity and function using NanoSIMS
    Tianlun Li
    Cemagref, Unité de Recherche Hydrosystèmes et Bioprocédés, Parc de Tourvoie, BP 44, 92163 Antony cedex, France
    Environ Microbiol 10:580-8. 2008
    ..The applicability of this new technique to the study of in situ ecophysiology of uncultured microorganisms within complex microbial communities is illustrated...
  22. ncbi Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil
    Luciana Trilles
    Molecular Mycology Research Laboratory, Center for Infectious Diseases and Microbiology, Westmead Hospital, Westmead Millennium Institute, Western Clinical School, University of Sydney, Sydney, Australia
    Mem Inst Oswaldo Cruz 103:455-62. 2008
    ....
  23. ncbi Prevalence and risk factor analysis of livestock associated MRSA-positive pig herds in The Netherlands
    E M Broens
    Quantitative Veterinary Epidemiology Group, Wageningen Institute of Animal Sciences, Wageningen University, P O Box 338, 6700 AH Wageningen, The Netherlands
    Prev Vet Med 102:41-9. 2011
    ..Herd size appeared to be a compilation of several factors, which made larger herds more often MRSA positive...
  24. ncbi Culture clash: challenging the dogma of microbial diversity
    Stuart P Donachie
    Department of Microbiology, University of Hawai i, Honolulu, HI, USA
    ISME J 1:97-9. 2007
  25. ncbi Rubrobacter bracarensis sp. nov., a novel member of the genus Rubrobacter isolated from a biodeteriorated monument
    Valme Jurado
    Instituto de Recursos Naturales y Agrobiologia, IRNAS CSIC, Av Reina Mercedes 10, 41012 Sevilla, Spain
    Syst Appl Microbiol 35:306-9. 2012
    ..These data clearly showed that the three strains could represent a new species, for which we propose the name Rubrobacter bracarensis sp. nov., with strain VF70612_S1(T) (=CECT 7924=DSMZ 24908) as the type strain...
  26. ncbi Microbes on building materials--evaluation of DNA extraction protocols as common basis for molecular analysis
    Jörg D Ettenauer
    VIBT BOKU, University of Natural Resources and Life Sciences, Department of Biotechnology, Muthgasse 11, A 1190 Vienna, Austria
    Sci Total Environ 439:44-53. 2012
    ..Therefore, we suggest this method as a gold standard for quantification of indoor fungi and bacteria in building materials...
  27. ncbi What is on that keyboard? Detecting hidden environmental reservoirs of Clostridium difficile during an outbreak associated with North American pulsed-field gel electrophoresis type 1 strains
    Donald M Dumford
    Department of Medicine, University Hospitals of Cleveland, Cleveland, OH, USA
    Am J Infect Control 37:15-9. 2009
    ..However, less information is available regarding the frequency of contamination of environmental surfaces outside of CDI isolation rooms...
  28. ncbi Replication, lies and lesser-known truths regarding experimental design in environmental microbiology
    Jay T Lennon
    W K Kellogg Biological Station Department of Microbiology and Molecular Genetics, Michigan State University, Hickory Corners, MI 49060, USA
    Environ Microbiol 13:1383-6. 2011
    ..Here, I provide examples where unreplicated data can be used to test hypotheses and yield novel information in a statistically robust manner...
  29. pmc Quantitative metagenomic analyses based on average genome size normalization
    Jeremy A Frank
    Department of Microbiology, University of Copenhagen, Sølvgade 83H, Copenhagen DK 1307, Denmark
    Appl Environ Microbiol 77:2513-21. 2011
    ....
  30. ncbi Validation of a partial rpoB gene sequence as a tool for phylogenetic identification of aeromonads isolated from environmental sources
    Brigitte Lamy
    Centre Hospitalier du Bassin de Thau, Sete, France
    Can J Microbiol 56:217-28. 2010
    ..hydrophila subsp. anaerogenes is similar to A. caviae and should be considered synonymous...
  31. ncbi Ammonia-oxidising archaea--physiology, ecology and evolution
    Christa Schleper
    Department of Genetics in Ecology, University of Vienna, Vienna, Austria
    Adv Microb Physiol 57:1-41. 2010
    ....
  32. ncbi Evaluation of VNTR typing for the identification of Mycobacterium ulcerans in environmental samples from Victoria, Australia
    Caroline J Lavender
    Mycobacterium Reference Laboratory, Victorian Infectious Diseases Reference Laboratory, 10 Wreckyn Street, North Melbourne, Victoria, Australia
    FEMS Microbiol Lett 287:250-5. 2008
    ..ulcerans being detected was indistinguishable from the strain causing disease in humans in that region...
  33. ncbi Protists are microbes too: a perspective
    David A Caron
    Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089 0371, USA
    ISME J 3:4-12. 2009
    ....
  34. ncbi DGGE/TGGE a method for identifying genes from natural ecosystems
    G Muyzer
    Netherlands Institute for Sea Research NL 1790 AB Den Burg, The Netherlands
    Curr Opin Microbiol 2:317-22. 1999
    ..of denaturing gradient gel electrophoresis(DGGE) and temperature gradient gel electrophoresis (TGGE) in environmental microbiology these techniques are now routinely used in many microbiological laboratories worldwide as molecular ..
  35. pmc Phylogenetic comparison of the methanogenic communities from an acidic, oligotrophic fen and an anaerobic digester treating municipal wastewater sludge
    Lisa M Steinberg
    Department of Civil and Environmental Engineering, The Pennsylvania State University, University Park, PA 16802, USA
    Appl Environ Microbiol 74:6663-71. 2008
    ..Diversity indices for the 16S rRNA gene library of the bog and both mcrA libraries were similar, but these indices indicated much lower diversity in the 16S digester library than in the other three libraries...
  36. ncbi A wide host-range metagenomic library from a waste water treatment plant yields a novel alcohol/aldehyde dehydrogenase
    Margaret Wexler
    School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK
    Environ Microbiol 7:1917-26. 2005
    ..These observations show that the use of wide host-range vectors enhances the efficacy with which metagenomic libraries can be screened for genes that confer novel functions...
  37. pmc Environmental proteomics: a paradigm shift in characterizing microbial activities at the molecular level
    Martin Keller
    Biosciences Division, Oak Ridge National Laboratory, One Bethel Valley Road, P O Box 2008, MS 6026, Oak Ridge, TN 37831, USA
    Microbiol Mol Biol Rev 73:62-70. 2009
    ..The review closes with a discussion of critical improvements in the area of integrating experimental mass spectrometry technologies with bioinformatics as well as improved sample handling...
  38. ncbi Comparison of the efficacy of a hydrogen peroxide dry-mist disinfection system and sodium hypochlorite solution for eradication of Clostridium difficile spores
    F Barbut
    National Reference Laboratory for Clostridium difficile, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Paris
    Infect Control Hosp Epidemiol 30:507-14. 2009
    ..To compare a hydrogen peroxide dry-mist system and a 0.5% hypochlorite solution with respect to their ability to disinfect Clostridium difficile-contaminated surfaces in vitro and in situ...
  39. ncbi Metagenomics: genomic analysis of microbial communities
    Christian S Riesenfeld
    Department of Plant Pathology, University of Wisconsin Madison, Wisconsin 53706, USA
    Annu Rev Genet 38:525-52. 2004
    ..This review describes progress toward understanding the biology of uncultured Bacteria, Archaea, and viruses through metagenomic analyses...
  40. pmc Identification of Mycobacterium ulcerans in the environment from regions in Southeast Australia in which it is endemic with sequence capture-PCR
    T Stinear
    Department of Microbiology, Monash University, Clayton, Victoria, Australia
    Appl Environ Microbiol 66:3206-13. 2000
    ..ulcerans may be transmitted from a point environmental source and demonstrate the utility of magnetic bead sequence capture-PCR for identification of nonculturable microbial pathogens in the environment...
  41. pmc IMG/M: a data management and analysis system for metagenomes
    Victor M Markowitz
    Biological Data Management and Technology Center, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, USA
    Nucleic Acids Res 36:D534-8. 2008
    ..IMG/M provides IMG's comparative data analysis tools extended to handle metagenome data, together with metagenome-specific analysis tools. IMG/M is available at http://img.jgi.doe.gov/m...
  42. ncbi Metabolically active microbial communities of yellow and grey colonizations on the walls of Altamira Cave, Spain
    M C Portillo
    Instituto de Recursos Naturales y Agrobiologia, CSIC, Avda Reina Mercedes, Sevilla, Spain
    J Appl Microbiol 104:681-91. 2008
    ..To determine the major components of total and metabolically active microbial communities of yellow and grey colonizations threatening the conservation of palaeolithic paintings in Altamira Cave (Spain)...
  43. ncbi Proteogenomics for environmental microbiology
    Jean Armengaud
    CEA, DSV, IBEB, Lab Biochim System Perturb, Bagnols sur Ceze, France
    Proteomics 13:2731-42. 2013
    ..They illustrate the advent of a new era of environmental microbiology where proteomics and genomics are intimately integrated to answer key biological questions.
  44. pmc Multilocus sequence typing supports the hypothesis that Ochrobactrum anthropi displays a human-associated subpopulation
    Sara Romano
    Faculte de Pharmacie, Laboratoire de Bacteriologie virologie, Universite Montpellier 1, 34093 Montpellier Cedex 5, France
    BMC Microbiol 9:267. 2009
    ..To address this issue, we proposed a polyphasic approach consisting in Multi-Locus Sequence Typing (MLST), multi-locus phylogeny, genomic-based fingerprinting by pulsed-field gel electrophoresis (PFGE) and antibiotyping...
  45. ncbi Feasibility of removing surface deposits on stone using biological and chemical remediation methods
    A Polo
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, Universita degli Studi di Milano, Via Celoria 2, Milan, Italy
    Microb Ecol 60:1-14. 2010
    ..The reported case study reveals that conservators can benefit from an integrated biotechnological approach aimed at the biocleaning of chemical alterations and the abatement of biodeteriogens...
  46. ncbi Gene cassettes encoding resistance to quaternary ammonium compounds: a role in the origin of clinical class 1 integrons?
    Michael R Gillings
    Department of Biological Sciences, Macquarie University, Sydney, New South Wales, Australia
    ISME J 3:209-15. 2009
    ....
  47. ncbi Role of copper in reducing hospital environment contamination
    A L Casey
    University Hospitals Birmingham NHS Foundation Trust, The Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK
    J Hosp Infect 74:72-7. 2010
    ..The use of copper-containing materials for surfaces in the hospital environment may therefore be a valuable adjunct for the prevention of HCAIs and requires further evaluation...
  48. ncbi Characterization of the microbial acid mine drainage microbial community using culturing and direct sequencing techniques
    Ryan R Auld
    Department of Chemistry and Biochemistry, Laurentian University, Canada
    J Microbiol Methods 93:108-15. 2013
    ....
  49. ncbi Monitoring the colonization of monuments by bacteria: cultivation versus molecular methods
    Leonila Laiz
    Instituto de Recursos Naturales y Agrobiologia, CSIC, Apartado 1052, Avenida Reina Mercedes, 10, 41012 Sevilla, Spain
    Environ Microbiol 5:72-4. 2003
    ..The data suggest that plating leads to an overestimation of the number of spore-forming bacteria with respect to quiescent vegetative forms; the latter are less easily cultured, but are readily detected by culture-independent techniques...
  50. ncbi Microbial nitrogen cycles: physiology, genomics and applications
    R W Ye
    DuPont Experimental Station, Wilmington, Delaware 19880, USA
    Curr Opin Microbiol 4:307-12. 2001
    ..Microbial nitrogen metabolism has industrial applications ranging from wastewater treatment to bioremediation and potential future use in biocatalysis for chemical production...
  51. ncbi Evaluating short-term changes in recreational water quality during a hydrograph event using a combination of microbial tracers, environmental microbiology, microbial source tracking and hydrological techniques: a case study in Southwest Wales, UK
    Mark D Wyer
    Centre for Research into Environment and Health, River Basin Dynamics and Hydrology Research Group, Institute of Geography and Earth Sciences, Aberystwyth University, Penglais, Aberystwyth, Ceredigion SY23 3DB, UK
    Water Res 44:4783-95. 2010
    ..This integration of tracers and MST offers additional information on the movement and individual sources causing water quality impairment...
  52. ncbi The identification of microorganisms by fluorescence in situ hybridisation
    R Amann
    Molecular Ecology Group, Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D 28359, Bremen, Germany
    Curr Opin Biotechnol 12:231-6. 2001
    ..Over the past year there have been a number of methodological developments in this area and new applications of FISH in microbial ecology and biotechnology have been reported...
  53. pmc Molecular monitoring of the microbial dynamics occurring on historical limestone buildings during and after the in situ application of different bio-consolidation treatments
    Jörg Ettenauer
    Institute of Applied Microbiology, Department of Biotechnology, Vienna Institute of Bio Technology VIBT, University of Natural Resources and Life Sciences, Muthgasse 11, A 1190 Vienna, Austria
    Sci Total Environ 409:5337-52. 2011
    ..The treatments seem to activate no dangerous microorganisms and furthermore, to select the remainder of a homogeneous group of carbonatogenic bacteria on the stones after a long period of time...
  54. ncbi Survival of prototype strains of somatic coliphage families in environmental waters and when exposed to UV low-pressure monochromatic radiation or heat
    Hee Suk Lee
    Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Water Res 45:3723-34. 2011
    ....
  55. pmc PCR amplification-independent methods for detection of microbial communities by the high-density microarray PhyloChip
    Kristen M DeAngelis
    Ecology Department, Earth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Appl Environ Microbiol 77:6313-22. 2011
    ....
  56. ncbi Phylogeny and distribution of the soxB gene among thiosulfate-oxidizing bacteria
    R Petri
    , , 24105, Kiel, Germany
    FEMS Microbiol Lett 197:171-8. 2001
    ....
  57. ncbi Diversity and ecology of psychrophilic microorganisms
    Rosa Margesin
    Institute of Microbiology, University of Innsbruck, Technikerstrasse 25, A 6020 Innsbruck, Austria
    Res Microbiol 162:346-61. 2011
    ....
  58. pmc Detection of Coxiella burnetii in complex matrices by using multiplex quantitative PCR during a major Q fever outbreak in The Netherlands
    A de Bruin
    National Institute for Public Health and the Environment RIVM, Centre for Infectious Disease Control CIb, Laboratory for Zoonoses and Environmental Microbiology, Bilthoven, The Netherlands
    Appl Environ Microbiol 77:6516-23. 2011
    ..burnetii targets in one multiplex qPCR assay showed that complex veterinary and environmental matrices can be screened reliably for the presence of C. burnetii DNA during an outbreak...
  59. ncbi Promises and pitfalls of recent advances in chemical means of preventing the spread of nosocomial infections by environmental surfaces
    Syed A Sattar
    Centre for Research on Environmental Microbiology CREM, Faculty of Medicine, University of Ottawa, Ontario, Canada
    Am J Infect Control 38:S34-40. 2010
    ....
  60. pmc Immunoglobulin G antibodies against indoor dampness-related microbes and adult-onset asthma: a population-based incident case-control study
    M S Jaakkola
    Department of Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    Clin Exp Immunol 129:107-12. 2002
    ..There was no evidence of a dose-response relation between the IgG antibody level and the risk of asthma. T. citrinoviride may play a role in the aetiology of adult-onset asthma or serve as an indicator of other causal factors...
  61. pmc Escherichia coli and selected veterinary and zoonotic pathogens isolated from environmental sites in companion animal veterinary hospitals in southern Ontario
    Colleen P Murphy
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario
    Can Vet J 51:963-72. 2010
    ..There is an environmental reservoir of pathogens in veterinary hospitals; therefore, additional studies are required to characterize risk factors associated with HAI in companion animals, including the role of the environment...
  62. ncbi Differential habitat use and niche partitioning by Pseudomonas species in human homes
    Susanna K Remold
    Department of Biology, University of Louisville, 137 Life Sciences Building, Louisville, KY 40292, USA
    Microb Ecol 62:505-17. 2011
    ..Furthermore, niche partitioning driven by competition among Pseudomonas species may be contributing to the observed variability in habitat use by Pseudomonas in this system...
  63. pmc Environmental isolates of Burkholderia pseudomallei in Ceará State, northeastern Brazil
    Dione B Rolim
    Postgraduate Program in Medical Science, Faculty of Medicine, Federal University of Ceara, Fortaleza, Ceara, Brazil
    Appl Environ Microbiol 75:1215-8. 2009
    ..This study investigated two municipalities in Ceará state where melioidosis cases have been confirmed to occur. Burkholderia pseudomallei was isolated in 26 (4.3%) of 600 samples in the dry and rainy seasons...
  64. ncbi Global Pseudomonas aeruginosa biodiversity as reflected in a Belgian river
    Jean Paul Pirnay
    Laboratory of Microbial Interactions, Department of Molecular and Cellular Interactions, Flanders Interuniversity Institute of Biotechnology, Vrije Universiteit Brussel, B 1050 Brussels, Belgium
    Environ Microbiol 7:969-80. 2005
    ..These findings illustrate the significance of river water as a reservoir and source of distribution of potentially pathogenic P. aeruginosa strains and could have repercussions on antinosocomial infection strategies...
  65. ncbi Comparison of sampling methods used for MRSA-classification of herds with breeding pigs
    E M Broens
    Quantitative Veterinary Epidemiology Group, Wageningen Institute of Animal Sciences, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands
    Vet Microbiol 147:440-4. 2011
    ..Individual analysis of environmental wipes is highly recommended, as pooling 5 environmental samples resulted in a substantial reduction of the apparent prevalence...
  66. ncbi When metagenomics meets stable-isotope probing: progress and perspectives
    Yin Chen
    Department of Biological Sciences, The University of Warwick, Coventry CV4 7AL, UK
    Trends Microbiol 18:157-63. 2010
    ..The combination of DNA-SIP and metagenomics not only permits the detection of rare low-abundance species from metagenomic libraries but also facilitates the detection of novel enzymes and bioactive compounds...
  67. ncbi The search and destroy strategy prevents spread and long-term carriage of methicillin-resistant Staphylococcus aureus: results from the follow-up screening of a large ST22 (E-MRSA 15) outbreak in Denmark
    S Böcher
    National Center for Antimicrobials and Infection Control, Statens Serum Institut, Copenhagen, Denmark
    Clin Microbiol Infect 16:1427-34. 2010
    ..At the end of follow-up, ten of 16 long-term carriers and the two household contacts were MRSA-negative. In conclusion, decolonization of MRSA carriers is possible, but should include treatment of household members and the environment...
  68. ncbi Cultivation gives context to the microbial ecologist
    Dominica Nichols
    Department of Biology, Northeastern University, Boston, MA, USA
    FEMS Microbiol Ecol 60:351-7. 2007
  69. pmc Detection of Coxiella burnetii DNA on small-ruminant farms during a Q fever outbreak in the Netherlands
    A de Bruin
    National Institute for Public Health and the Environment RIVM, Centre for Infectious Disease Control CIb, Bilthoven, Netherlands
    Appl Environ Microbiol 78:1652-7. 2012
    ..burnetii to humans...
  70. ncbi Influence of selective media on successful detection of Shiga toxin-producing Escherichia coli in food, fecal, and environmental samples
    Hussein S Hussein
    Department of Animal Biotechnology, University of Nevada Reno, Reno, Nevada
    Foodborne Pathog Dis 5:227-44. 2008
    ..Future research should focus on identifying possible antibiotic combinations that effectively inhibit most background bacteria without affecting pathogenic STEC strains in the test sample...
  71. pmc Validation of a nylon-flocked-swab protocol for efficient recovery of bacterial spores from smooth and rough surfaces
    Alexander Probst
    Institute of Microbiology and Archaea Center, University of Regensburg, Universitaetsstrasse 31, 93053 Regensburg, Germany
    Appl Environ Microbiol 76:5148-58. 2010
    ..anthracis contamination for law enforcement and security efforts...
  72. ncbi Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors
    S Buffet-Bataillon
    Unité d Hygiène Hospitalière, Pôle Microorganismes, CHU Pontchaillou, Rennes, France
    J Hosp Infect 72:17-22. 2009
    ..Prompt intervention and strict adherence to alcoholic hand disinfection were the key factors that led to the successful control of this outbreak...
  73. pmc Low-density macroarray targeting non-locus of enterocyte effacement effectors (nle genes) and major virulence factors of Shiga toxin-producing Escherichia coli (STEC): a new approach for molecular risk assessment of STEC isolates
    Marie Bugarel
    French Food Safety Agency, Food Quality and Agro alimentary Processes Research Laboratory, avenue du General de Gaulle, F 94706 Maisons Alfort, France
    Appl Environ Microbiol 76:203-11. 2010
    ..The presence of eae, ent/espL2, nleB, nleE, and nleH1-2 genes is a clear signature of STEC strains with high virulence for humans...
  74. ncbi Environmental contamination during a carbapenem-resistant Acinetobacter baumannii outbreak in an intensive care unit
    G Aygun
    Department of Microbiology and Clinical Microbiology, Cerrahpasa Medical Faculty, University of Istanbul 34303, Aksaray, Istanbul, Turkey
    J Hosp Infect 52:259-62. 2002
    ..No bacteria were grown on repeat environmental cultures. Environmental contamination has an important reservoir role in outbreaks of A. baumannii in ICUs and must be eradicated in order to overcome such outbreaks...
  75. pmc Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria
    Jeffrey W Craig
    Howard Hughes Medical Institute, Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
    Appl Environ Microbiol 76:1633-41. 2010
    ....
  76. ncbi Applications of real-time polymerase chain reaction for quantification of microorganisms in environmental samples
    Tong Zhang
    Environmental Biotechnology Laboratory, Department of Civil Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    Appl Microbiol Biotechnol 70:281-9. 2006
    ..The applications of qRT-PCR for the quantification of microorganisms in the environment are also summarized...
  77. ncbi Methanotrophs and copper
    Jeremy D Semrau
    Department of Civil and Environmental Engineering, The University of Michigan, Ann Arbor, MI, USA
    FEMS Microbiol Rev 34:496-531. 2010
    ....
  78. pmc Effect of oxygen on growth of Mycobacterium ulcerans in the BACTEC system
    J C Palomino
    Mycobacteriology Unit, Institute of Tropical Medicine, Antwerp, Belgium
    J Clin Microbiol 36:3420-2. 1998
    ..Application of this observation may improve rates of isolation of M. ulcerans in primary culture from clinical samples and promote isolation of the bacterium from environmental sources...
  79. ncbi Microbial monitoring of spacecraft and associated environments
    M T La Duc
    Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109, USA
    Microb Ecol 47:150-8. 2004
    ..Each of the methods tested in this study has its advantages, and by coupling two or more of these techniques even more reliable information as to microbial burden is rapidly obtained...
  80. pmc Isolation and characterization of metalloproteases with a novel domain structure by construction and screening of metagenomic libraries
    Tanja Waschkowitz
    Abteilung Genomische und Angewandte Mikrobiologie, Institut für Mikrobiologie und Genetik der Georg August Universität, Grisebachstr 8, 37077 Gottingen, Germany
    Appl Environ Microbiol 75:2506-16. 2009
    ..The optimum pH and temperature of both proteases were 8.0 and 65 degrees C, respectively, when casein was used as substrate...
  81. ncbi Stable-isotope probing of nucleic acids: a window to the function of uncultured microorganisms
    Stefan Radajewski
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Opin Biotechnol 14:296-302. 2003
    ..Investigations using labelled substrates, or which detect variations in the natural abundance of isotopes, have thus revealed the metabolic function of microorganisms without the need to isolate them in culture...
  82. ncbi Recovery of diverse genes for class 1 integron-integrases from environmental DNA samples
    Michael R Gillings
    Department of Biological Sciences, Genes to Geoscience Research Centre, Macquarie University, Sydney, NSW, Australia
    FEMS Microbiol Lett 287:56-62. 2008
    ..IntI1 was common in environmental samples and exhibited previously unsuspected sequence diversity. The method allowed discrimination between clinical and environmental variants of intI1...
  83. pmc Phylogenetic classification of short environmental DNA fragments
    Lutz Krause
    Center for Biotechnology CeBiTec, Bioinformatics Resource Facility BRF, Bielefeld University, D 33594 Bielefeld, Germany
    Nucleic Acids Res 36:2230-9. 2008
    ..The algorithm was applied in a comparative study of three aquatic microbial samples obtained by 454 pyrosequencing. Profound differences in the taxonomic composition of these samples could be clearly revealed...
  84. ncbi Diversity of ammonia monooxygenase operon in autotrophic ammonia-oxidizing bacteria
    Jeanette M Norton
    Department of Plants, Soils and Biometeorology, Utah State University, Logan, UT 84322 4820, USA
    Arch Microbiol 177:139-49. 2002
    ..Electronic supplementary material to this paper can be obtained by using the Springer LINK server located at http://dx.doi.org/10.1007/s00203-001-0369-z...
  85. ncbi Metagenomics--the key to the uncultured microbes
    Wolfgang R Streit
    Institut fur Mikrobiologie und Genetik, Universitat Gottingen, Grisebachstr 8, 37077, Gottingen, Germany
    Curr Opin Microbiol 7:492-8. 2004
    ..Using the metagenome sequences to fully understand how complex microbial communities function and how microbes interact within these niches represents a major challenge for microbiologists today...
  86. ncbi Antibiotic exposure and room contamination among patients colonized with vancomycin-resistant enterococci
    Marci Drees
    Tufts Medical Center, Tufts University, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 29:709-15. 2008
    ..To determine whether total and antianaerobic antibiotic exposure increases the risk of room contamination among vancomycin-resistant enterococci (VRE)-colonized patients...
  87. pmc Microviridae goes temperate: microvirus-related proviruses reside in the genomes of Bacteroidetes
    Mart Krupovic
    Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Department of Microbiology, Institut Pasteur, Paris, France
    PLoS ONE 6:e19893. 2011
    ....
  88. ncbi Visual and statistical comparison of metagenomes
    Suparna Mitra
    Center for Bioinformatics ZBIT, Tubingen University, Sand 14, 72076 Tubingen, Germany
    Bioinformatics 25:1849-55. 2009
    ..One major challenge is how to compare multiple datasets. Furthermore, there is a need for bioinformatics tools that can process many large datasets and are easy to use...
  89. ncbi Identification of bacterial plasmids based on mobility and plasmid population biology
    Maria Pilar Garcillán-Barcia
    Departamento de Biología Molecular e Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria CSIC IDICAN, C Herrera Oria s n, Santander, Spain
    FEMS Microbiol Rev 35:936-56. 2011
    ..We would like to propose that, by using an identification methodology based on plasmid mobility types, we can follow the propagation routes of most plasmids in ?-proteobacteria, as well as their cargo genes, in complex ecosystems...
  90. ncbi Seasonality of rDNA- and rRNA-derived archaeal communities and methanogenic potential in a boreal mire
    Heli Juottonen
    Department of Biological and Environmental Sciences, General Microbiology, University of Helsinki, Helsinki, Finland
    ISME J 2:1157-68. 2008
    ..Detection of mRNA of the methanogenic mcrA gene confirmed activity of methanogens in winter, accounting for previously reported winter CH(4) emissions...
  91. pmc mcrA-targeted real-time quantitative PCR method to examine methanogen communities
    Lisa M Steinberg
    Department of Civil and Environmental Engineering, The Pennsylvania State University, University Park, 16802, USA
    Appl Environ Microbiol 75:4435-42. 2009
    ..The TaqMan qPCR assays were successfully able to determine the environmental abundance of different phylogenetic groups of methanogens, including several groups with few or no cultivated members...
  92. ncbi Prokaryotic diversity--magnitude, dynamics, and controlling factors
    Vigdis Torsvik
    Department of Microbiology, University of Bergen, Jahnebakken 5, N 5020 Bergen, Norway
    Science 296:1064-6. 2002
    ..Hypotheses and models explaining such differences are under development and are beginning to offer promising insights into the mechanisms governing prokaryote diversity and ecosystem function...
  93. pmc Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, Ohio, USA
    BMC Infect Dis 10:197. 2010
    ..Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also safe, rapid, and automated...
  94. ncbi Crystal ball. The viriosphere: the greatest biological diversity on Earth and driver of global processes
    Curtis Suttle
    Earth and Ocean Sciences, Microbiology and Immunology, University of British Columbia, BC, Canada
    Environ Microbiol 7:481-2. 2005
  95. ncbi Exopolysaccharides from extremophiles: from fundamentals to biotechnology
    Barbara Nicolaus
    Istituto di Chimica Biomolecolare ICB, CNR Via Campi Flegrei 34, 80078, Pozzuoli NA, Italy
    Environ Technol 31:1145-58. 2010
    ..The commercial value of EPSs synthesized by microorganisms from extreme habitats has been established recently...
  96. ncbi MRSA CC398 in the pig production chain
    E M Broens
    Quantitative Veterinary Epidemiology Group, Wageningen Institute of Animal Sciences, Wageningen University, P O Box 338, 6700 AH Wageningen, The Netherlands
    Prev Vet Med 98:182-9. 2011
    ..This underlined the need for the identification of additional risk factors for MRSA...
  97. ncbi Characterization of aerobic bacterial and fungal microbiota on surfaces of historic Scottish monuments
    Maija Liisa Suihko
    VTT Technical Research Centre of Finland, Espoo, Finland
    Syst Appl Microbiol 30:494-508. 2007
    ..Using in situ microscopy diatom algae were also detected...
  98. ncbi Microbial contamination of spacecraft
    D L Pierson
    NASA Johnson Space Center, Houston, TX, USA
    Gravit Space Biol Bull 14:1-6. 2001
    ..Equally important is a better understanding of the immune response and of human-microorganism-environment interactions during long-term space habitation...
  99. pmc The environment as an unrecognized reservoir for community-associated methicillin resistant Staphylococcus aureus USA300: a case-control study
    Anne Catrin Uhlemann
    Division of Infectious Diseases, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e22407. 2011
    ..Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are spreading, but the source of infections in non-epidemic settings remains poorly defined...
  100. ncbi Asymptomatic carriage of Klebsiella pneumoniae producing extended-spectrum beta-lactamase by patients in a neurological early rehabilitation unit: management of an outbreak
    R Hollander
    Landesuntersuchungsamt für Chemie, Hygiene und Veterinärmedizin, St Jürgenstr 1, D 28205 Bremen, Germany
    J Hosp Infect 48:207-13. 2001
    ..Disinfection of mucous membranes was difficult. Eventually the application of a nasal spray containing povidone-iodine proved to be successful...
  101. pmc A Stenotrophomonas maltophilia multilocus sequence typing scheme for inferring population structure
    Sabine Kaiser
    Institute of Environmental Medicine and Hospital Epidemiology at the University Medical Centre Freiburg, Breisacher Str 115 b, 79106 Freiburg, Germany
    J Bacteriol 191:2934-43. 2009
    ....

Research Grants57

  1. Environmental Microorganisms as Human Pathogens
    Gerard Cangelosi; Fiscal Year: 2004
    ..science of environmental pathogens often falls into a gray zone between infectious disease research and environmental microbiology. The American Academy of Microbiology plans to convene a group of international experts for a colloquium ..
  2. Spatial characterization of microbial communities in the cystic fibrosis lung
    RYAN COULSON HUNTER; Fiscal Year: 2013
    ..Here, my overarching goal is to apply standard environmental microbiology principles and methodologies to test the hypothesis that the complex chemistry of the bronchial tree ..
  3. Spatial characterization of microbial communities in the cystic fibrosis lung
    RYAN COULSON HUNTER; Fiscal Year: 2012
    ..Here, my overarching goal is to apply standard environmental microbiology principles and methodologies to test the hypothesis that the complex chemistry of the bronchial tree ..
  4. Microbiome-Based Risk Assessment: Reciprocal Effects of Arsenic on Environmental
    Stephanie Bachas-Daunert; Fiscal Year: 2013
    ..This research couples genomics, human microbial ecology, experimental environmental microbiology, and biochemistry, advancing environmental/public health risk assessment and possible interventions...
  5. Rapid Microbial Identification by MALDI-TOF Mass Spectrometry of Ribosomal RNA
    George W Jackson; Fiscal Year: 2010
    ..food and water safety, bioreactor analysis, sterility assurance in the pharmaceutical industry, environmental microbiology, and homeland security...
  6. Epidemiology of Emerging Infectious Diseases and Bioterrorism
    Julie Parsonnet; Fiscal Year: 2013
    ..Fellows can optionally receive training in other areas such as environmental microbiology and medical informatics...
  7. PSEUDOMONAS 1999--BIOTECHNOLOGY AND PATHOGENESIS
    JOANNA GOLDBERG; Fiscal Year: 1999
    ..topic of Pseudomonas research spans a number of disciplines, including cell biology, plant pathology, environmental microbiology, metabolism, and gene regulation...
  8. Kadner Institute for Graduate Students and Postdoctoral Scientists in Preparation
    Shelley M Payne; Fiscal Year: 2013
    ..structure and physiology, microbial genetics, clinical microbiology, medical microbiology, applied and environmental microbiology, virology, immunology, and public health...
  9. Rapid Microbial Identification by MALDI-TOF Mass Spectrometry of Ribosomal RNA
    George Jackson; Fiscal Year: 2007
    ..food and water safety, bioreactor analysis, sterility assurance in the pharmaceutical industry, environmental microbiology, and homeland security...
  10. Development of a LH-PCR Based Diagnostic for Inflammatory Bowel Disease
    Patrick Gillevet; Fiscal Year: 2007
    ..Studies that characterize microflora in humans using powerful techniques from environmental microbiology can bring about significant advances in the understanding of these illnesses...
  11. Single-Cell Analysis of Virus-Host Interactions
    Rob Phillips; Fiscal Year: 2013
    ..We argue that one of the central challenges in environmental microbiology is to map out which viruses are associated with which hosts and understand the flow of genetic ..
  12. MULTISPECTRAL BACTERIAL IDENTIFICATION
    STEVEN ROBLES; Fiscal Year: 2002
    ..of (unculturable) bacteria growing within consortia and biofilms, with applications in both clinical and environmental microbiology. PROPOSED COMMERCIAL APPLICATIONS: We shall provide an integrated technology platform to the general ..
  13. FASEB Summer Conference on Microbial Polysaccharides
    Arthur Tzianabos; Fiscal Year: 2004
    ..the exchange of new concepts in microbial pathogenesis and immunity, cell biology, plant pathology, environmental microbiology, metabolism, and gene regulation...
  14. FASEB SUMMER CONFERENCE--MICROBIAL POLYSACCHARIDES
    JOANNA GOLDBERG; Fiscal Year: 2000
    ..spans a number of disciplines, including infectious disease, cell biology, plant pathology, environmental microbiology, metabolism, and gene regulation...
  15. MULTISPECTRAL BACTERIAL IDENTIFICATION
    William Coleman; Fiscal Year: 1999
    ..This new technology for multispectral bacterial identification (Mbid) will benefit clinical and environmental microbiology as well as biotechnology...
  16. Appl.& Environ.Microbiol.Gordon Research Conference
    Judy Wall; Fiscal Year: 2003
    Description (provided by applicant) The Applied and Environmental Microbiology Gordon Research Conference is one of the longest running Gordon Conferences and has been held every two years since 1950...
  17. CONFERENCE ON MICROBE INTERACTIONS + THEIR ENVIRONMENTS
    Roberto Kolter; Fiscal Year: 2001
    ..development need to interact closely with scientists involved in genomics, evolution, mechanistics, and environmental microbiology. The multidisciplinary nature of the proposed speaker list clearly addressed this need...
  18. JSU Support for Continuous Research Excellence
    Hiroyasu Tachikawa; Fiscal Year: 2009
    ..Biomedical investigations will be conducted in the following areas: environmental microbiology, signal transduction, molecular genetics, environmental plant microbiology, analytical chemistry, ..
  19. DNA Packaging Motors
    Philip Serwer; Fiscal Year: 2005
    ..Analysis of bacteriophage DNA packaging motors is expected to provide a basis for understanding the role of motors in disease, especially disease caused by a virus that has a DNA packaging motor. ..
  20. Molecular examination of the identity and activity of Po
    EUGENE MADSEN; Fiscal Year: 2004
    ..abstract_text> ..
  21. Enhanced Capillary DNA Sequencing
    Philip Serwer; Fiscal Year: 2004
    ..Each adaptation will help solve a current genomic problem, for example, either closing of a partially assembled genome sequence or performing high accuracy analysis of mutations. ..
  22. Assembly Visualized Routine Flourescence Microscopy
    Philip Serwer; Fiscal Year: 2008
    ..Applications are anticipated in the analysis of the assembly of disease-causing viruses and determining pathways of oncogenesis. ..
  23. Cytokine-CRH Interactions in IFN-alfa-Induced Depression
    Charles Raison; Fiscal Year: 2009
    ..abstract_text> ..
  24. Metagenomic analysis of the human virome
    Eric L Delwart; Fiscal Year: 2010
    ..This metagenomic survey of non-human nucleic acids in humans will therefore begin the task of determining the full range of viral diversity in humans. ..
  25. Microbial Biofilms: Systems Biology Affecting Humans and the Environment
    John Costerton; Fiscal Year: 2005
    ..abstract_text> ..
  26. Native Americans in Biological Science at OK State Univ
    Robert Miller; Fiscal Year: 2008
    ..The NABS program provides a unique opportunity for the largest minority group in the state of Oklahoma, as it seeks to increase the number of Native Americans in biological science. ..
  27. A Staged Strategy for Virus Identification and Discovery
    W Ian Lipkin; Fiscal Year: 2005
    ..Our initial focus will be two chronic diseases where specific viral taxa are associated and potentially implicated in pathogenesis: bronchioalveolar cell carcinoma and amyotrophic lateral sclerosis. ..
  28. Cryptococcus gatti mating 1oci; mapping and gene study
    Vishnu Chaturvedi; Fiscal Year: 2004
    ..abstract_text> ..
  29. A DEVELOPMENTAL MODEL FOR AUTISM BASED ON CNS INFECTION
    WALTER LIPKIN; Fiscal Year: 2004
    ..4) Determine how opoptosis contributes to the neuropathology observed after neonatal infection. (5) Analyze regional changes in neurotransmitter systems following neonatal infection. ..
  30. REMOTE SENSING AND GIS FOR SCHISTOSOMIASIS CONTROL
    Robert Spear; Fiscal Year: 2002
    ..Subsequently, efforts will be made to make the classification more precise by supplementing these data with ecological and landscape data and to evaluate alternative remotely sensed data for their ability to predict risk areas. ..
  31. Plasticity in protocatechuate 3,4-dioxygenase & genes
    L Ornston; Fiscal Year: 2005
    ..Thus a unified technology will be applied to defining factors that determine variability and constancy in both protocatechuate 3,4-dioxygenase and its structural genes. ..
  32. BORNA DISEASE VIRUS AND NEUROPSYCHIATRIC DISEASE
    WALTER LIPKIN; Fiscal Year: 2002
    ..This study will be the first to collect and process human sera and PBMC samples in clinical laboratories with no history of BDV research and dispense aliquots to a central laboratory for randomized, blinded analysis. ..
  33. Control of Biofilms by Natural Products
    John Costerton; Fiscal Year: 2004
    ..The potential market penetration for potent biofilm inhibitors is exemplified by the sheer number of cases in which biofilms cause medical problems. ..
  34. Pathogen Discovery in Chronic Lung Disease by Mass Tag PCR and Microarray
    W Ian Lipkin; Fiscal Year: 2009
    ....
  35. Ecological relationships of Mycobacterium Infection
    RICHARD MERRITT; Fiscal Year: 2009
    ....
  36. Campylobacter jejuni outer membrane protein vaccine
    Stuart Thompson; Fiscal Year: 2009
    ..Specific Aim 3. We will determine whether immunization of mice with conserved, purified recombinant OMPs protects against subsequent experimental C. jejuni infection. ..
  37. Conference--The Global Genome: Microbes
    EDWARD DELONG; Fiscal Year: 2002
    ..The colloquium will be convened to develop the intellectual material that will comprise an analytical and comprehensive report. ..
  38. CAMPYLOBACTER FETUS SURFACE LAYER PROTEIN SECRETION
    Stuart Thompson; Fiscal Year: 2002
    ..coli. They will use deletion and mutational analyses to define the C. fetus SapA C-terminal secretion signal. The ability of the SapA secretion to mediate the transport of normally non-secreted proteins also will be assessed. ..
  39. Control of Biofilms by Natural Products
    John Costerton; Fiscal Year: 2001
    ..proposed commercial application: not available ..
  40. MOLECULAR ANALYSIS OF A NEUROTROPIC AGENT--BORNA VIRUS
    WALTER LIPKIN; Fiscal Year: 2002
    ....
  41. DNA Microchips: Detecting Microbes in Oral Cavity Fluids
    David Stahl; Fiscal Year: 2005
    ....
  42. Phage Binding for Continuous Anthrax Spore Detection
    VALERY PETRENKO; Fiscal Year: 2004
    ..Parallel experiments will also be conducted with antibody-derived probes for comparison evaluation of specificity, selectivity and longevity of the sensors. ..
  43. ENDOTOXIN AND ASTHMA PREVENTION IN YOUNG CHILDREN
    Andrew Liu; Fiscal Year: 2005
    ..A specific Research Career Development Plan has been designed by the Candidate that includes the research described above in order to accomplish the goals of this Award. ..
  44. Glucocorticoid Resistance in Immune-Based Depression
    Charles Raison; Fiscal Year: 2006
    ....
  45. Mass Tag PCR Detection of Respiratory Pathogens
    W Ian Lipkin; Fiscal Year: 2004
    ..abstract_text> ..
  46. Local Strategies for Schistosomiasis Control
    Robert Spear; Fiscal Year: 2006
    ....
  47. The role of aquatic Invertebrates in M. ulcerans Disease
    RICHARD MERRITT; Fiscal Year: 2006
    ..g., deforestation, agriculture), BU incidence, and limnological and biological characteristics of waterbodies to better understand the epidemiology of this important emerging disease. ..
  48. Campylobacter jejuni proteins induced at 37C
    Stuart Thompson; Fiscal Year: 2007
    ..jejuni proteins that are induced at 37C.Specific Aim 3. Elucidate the roles of specific 37C-induced proteins in human epithelial cell binding and invasion in vitro, and in colonization in a mouse model. ..
  49. Stringent response and bmp expression in B. burgdorferi
    Felipe Cabello; Fiscal Year: 2007
    ..burgdorferi from a descriptive paradigm to a paradigm framed by mechanistic and causal interpretations. ..
  50. Campylobacter jejuni DNA methylation and gene regulation
    Stuart Thompson; Fiscal Year: 2004
    ..Specific Aim 3. Elucidate the upstream factors and signals controlling Cj1461 and Cj0355 expression to reveal the entire regulatory circuit. ..
  51. Molecular Evolution of Eukaryotes: a protistan emphasis
    Mitchell Sogin; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  52. A Staged Strategy for Virus Identification and Discovery
    WALTER LIPKIN; Fiscal Year: 2004
    ..Consistent with aims proposed in AI51292, our initial clinical application will be to analyze enteroviral serotypes implicated in human disease in North America. ..
  53. Development of Noninvasive Bioluminescence Imaging for Cancer Diagnosis and Thera
    Gary Sayler; Fiscal Year: 2008
    ..This technology will provide the capability for imaging in vivo gene expression in early diagnosis, therapeutic efficacy and disease re-occurrence in whole animal models. [unreadable] [unreadable] [unreadable]..
  54. Environmental Bioinorganic Chemistry 2008 Gordon Research Conference
    Anne O Summers; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  55. Regulated expression of B. burgdorferi virulence genes
    FELIPE CARDENAS CABELLO; Fiscal Year: 2010
    ..burgdorferi. These tools will be used to identify genes that are potentially responsible for this organism's virulence and which could be targets for new vaccines and antibiotics against Lyme disease. ..