safety

Summary

Summary: Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.

Top Publications

  1. pmc Neighborhood-based differences in physical activity: an environment scale evaluation
    Brian E Saelens
    Division of Psychology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, MLC 3015, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Am J Public Health 93:1552-8. 2003
  2. ncbi Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Lancet 374:1533-42. 2009
  3. pmc Built environment correlates of walking: a review
    Brian E Saelens
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA, USA
    Med Sci Sports Exerc 40:S550-66. 2008
  4. ncbi Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study
    Henry Krum
    Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic, Australia
    Lancet 373:1275-81. 2009
  5. ncbi Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    Charles L Vogel
    University of Miami School of Medicine, Comprehensive Cancer Research Group Inc, and Columbia Cancer Research Network of Florida, Miami, FL, USA
    J Clin Oncol 20:719-26. 2002
  6. ncbi Variation in the safety of induced pluripotent stem cell lines
    Kyoko Miura
    Center for iPS Cell Research and Application CiRA, Kyoto University, Kyoto, Japan
    Nat Biotechnol 27:743-5. 2009
  7. ncbi Dietary flavonoids: bioavailability, metabolic effects, and safety
    Julie A Ross
    Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Annu Rev Nutr 22:19-34. 2002
  8. ncbi Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders
    Maria Ester Bernardo
    Department of Pediatric Hematology Oncology, IRCCS Bambino Gesù Children s Hospital, Rome, Italy
    Ann N Y Acad Sci 1266:107-17. 2012
  9. ncbi Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    Lancet 374:1694-702. 2009
  10. ncbi Relationship between the physical environment and physical activity in older adults: a systematic review
    Jelle Van Cauwenberg
    Department of Human Biometry and Biomechanics, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussel, Belgium
    Health Place 17:458-69. 2011

Detail Information

Publications272 found, 100 shown here

  1. pmc Neighborhood-based differences in physical activity: an environment scale evaluation
    Brian E Saelens
    Division of Psychology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, MLC 3015, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Am J Public Health 93:1552-8. 2003
    ..This study evaluated a neighborhood environment survey and compared the physical activity and weight status of the residents in 2 neighborhoods...
  2. ncbi Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Lancet 374:1533-42. 2009
    Intermittent preventive treatment (IPT) is a promising strategy for malaria control in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) with sulfadoxine-pyrimethamine in Africa.
  3. pmc Built environment correlates of walking: a review
    Brian E Saelens
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA, USA
    Med Sci Sports Exerc 40:S550-66. 2008
    ..This article reviews evidence on the built environment correlates with walking...
  4. ncbi Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study
    Henry Krum
    Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic, Australia
    Lancet 373:1275-81. 2009
    ..sympathetic denervation in patients with resistant hypertension (ie, systolic blood pressure >/=160 mm Hg on three or more antihypertensive medications, including a diuretic) to assess safety and blood-pressure reduction effectiveness.
  5. ncbi Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    Charles L Vogel
    University of Miami School of Medicine, Comprehensive Cancer Research Group Inc, and Columbia Cancer Research Network of Florida, Miami, FL, USA
    J Clin Oncol 20:719-26. 2002
    To evaluate the efficacy and safety of first-line, single-agent trastuzumab in women with HER2-overexpressing metastatic breast cancer.
  6. ncbi Variation in the safety of induced pluripotent stem cell lines
    Kyoko Miura
    Center for iPS Cell Research and Application CiRA, Kyoto University, Kyoto, Japan
    Nat Biotechnol 27:743-5. 2009
    ..In contrast, SNS from iPS cells derived from different adult tissues varied substantially in their teratoma-forming propensity, which correlated with the persistence of undifferentiated cells...
  7. ncbi Dietary flavonoids: bioavailability, metabolic effects, and safety
    Julie A Ross
    Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Annu Rev Nutr 22:19-34. 2002
    ..Because there are many biological activities attributed to the flavonoids, some of which could be beneficial or detrimental depending on specific circumstances, further studies in both the laboratory and with populations are warranted...
  8. ncbi Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders
    Maria Ester Bernardo
    Department of Pediatric Hematology Oncology, IRCCS Bambino Gesù Children s Hospital, Rome, Italy
    Ann N Y Acad Sci 1266:107-17. 2012
    ..Experimental studies in animal models and phase I/II clinical trials on the use of MSCs for the treatment of IBDs and other inflammatory/degenerative conditions are reviewed...
  9. ncbi Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    Lancet 374:1694-702. 2009
    ..To expand the use of this vaccine, it was modified to comply with WHO standards. We assessed the efficacy and safety of this modified vaccine in a population with endemic cholera.
  10. ncbi Relationship between the physical environment and physical activity in older adults: a systematic review
    Jelle Van Cauwenberg
    Department of Human Biometry and Biomechanics, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussel, Belgium
    Health Place 17:458-69. 2011
    ..More studies in different contexts utilizing longitudinal designs, standardized, reliable and validated PA and environmental measurements and investigating possible moderating effects are definitely warranted...
  11. ncbi Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine in women aged 24-45 years: a randomised, double-blind trial
    Nubia Munoz
    National Institute of Cancer, Bogota, Colombia
    Lancet 373:1949-57. 2009
    ..We tested the safety, immunogenicity, and efficacy of the quadrivalent HPV (types 6, 11, 16, 18) L1 virus-like-particle vaccine in ..
  12. pmc Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
    M Schiff
    Denver Arthritis Clinic, 200 Spruce Street 100, Denver, CO 80230, USA
    Ann Rheum Dis 67:1096-103. 2008
    This double-blind trial evaluated the efficacy and safety of abatacept or infliximab vs placebo...
  13. pmc A smartphone-based driver safety monitoring system using data fusion
    Boon Giin Lee
    Department of Electronic Engineering, Pukyong National University, Busan 608 737, Korea
    Sensors (Basel) 12:17536-52. 2012
    This paper proposes a method for monitoring driver safety levels using a data fusion approach based on several discrete data types: eye features, bio-signal variation, in-vehicle temperature, and vehicle speed...
  14. ncbi Nanomaterials in the construction industry: a review of their applications and environmental health and safety considerations
    Jaesang Lee
    Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, USA
    ACS Nano 4:3580-90. 2010
    ....
  15. pmc Evolution, safety, and highly pathogenic influenza viruses
    Marc Lipsitch
    Center for Communicable Disease Dynamics and Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Science 336:1529-31. 2012
    ..Thus, we propose that future experiments with virulent pathogens whose accidental or deliberate release could lead to extensive spread in human populations should be limited by explicit risk-benefit considerations...
  16. ncbi Safety of acupuncture: results of a prospective observational study with 229,230 patients and introduction of a medical information and consent form
    Claudia M Witt
    Institute for Social Medicine, Epidemiology, and Health Economics, Charite University Medical Center, Berlin, Germany
    Forsch Komplementmed 16:91-7. 2009
    To evaluate the safety of acupuncture in a large number of patients receiving conventional health care and, based on these results, to develop a new medical consent form for acupuncture.
  17. ncbi Neighborhood disorder, perceived safety, and readiness to encourage use of local playgrounds
    Rebecca Miles
    Department of Urban and Regional Planning, Florida State University, Tallahassee, Florida 32306 2280, USA
    Am J Prev Med 34:275-81. 2008
    ..the neighborhood physical environment and adults' readiness to encourage children's use of local playgrounds, and the extent to which perceived safety acts as a mediator, can inform efforts to increase children's physical activity.
  18. ncbi Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
    W S Redfern
    Safety Assessment UK, AstraZeneca R and D Alderley Park, Macclesfield, Cheshire, UK
    Cardiovasc Res 58:32-45. 2003
    ..To attempt to determine the relative value of preclinical cardiac electrophysiology data (in vitro and in vivo) for predicting risk of torsade de pointes (TdP) in clinical use...
  19. pmc Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa
    Tony Hawkridge
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Diseases and Molecular Medicine, and School of Child and Adolescent Health, University of Cape Town, Observatory, South Africa
    J Infect Dis 198:544-52. 2008
    ..One leading booster vaccine, MVA85A (where "MVA" denotes "modified vaccinia virus Ankara"), has shown promising safety and immunogenicity in human trials performed in the United Kingdom...
  20. ncbi Patient involvement in patient safety: what factors influence patient participation and engagement?
    Rachel E Davis
    Clinical Safety Research Unit, Department of Bio Surgery and Surgical Technology, QEQM, St Mary s Hospital, London, UK
    Health Expect 10:259-67. 2007
    Patients can play an important role in improving patient safety by becoming actively involved in their health care. However, there is a paucity of empirical data on the extent to which patients take on such a role...
  21. ncbi The efficacy and safety of Dermagraft in improving the healing of chronic diabetic foot ulcers: results of a prospective randomized trial
    William A Marston
    University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7212, USA
    Diabetes Care 26:1701-5. 2003
    ..To determine if a human fibroblast-derived dermal substitute could promote the healing of diabetic foot ulcers...
  22. ncbi Perceived environmental correlates of physical activity for leisure and transportation in Curitiba, Brazil
    Diana C Parra
    Prevention Research Center in St Louis, George Warren Brown School of Social Work, Washington University in St Louis, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Prev Med 52:234-8. 2011
    ..Physical activity (PA) has consistently been associated with perceived environmental characteristics...
  23. ncbi Efficacy and safety of automatic remote monitoring for implantable cardioverter-defibrillator follow-up: the Lumos-T Safely Reduces Routine Office Device Follow-up (TRUST) trial
    Niraj Varma
    Cardiac Pacing and Electrophysiology, Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Circulation 122:325-32. 2010
    ....
  24. ncbi The built environment, neighborhood crime and constrained physical activity: an exploration of inconsistent findings
    Sarah Foster
    School of Population Health, The University of Western Australia, Crawley, Western Australia, Australia
    Prev Med 47:241-51. 2008
    Personal safety is commonly cited in qualitative research as a barrier to local walking, yet the relationship between safety and constrained physical activity has received mixed support in quantitative studies...
  25. ncbi Dietary intake of stearidonic acid-enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety
    Shawna L Lemke
    Monsanto Company, St Louis, MO 63167, USA
    Am J Clin Nutr 92:766-75. 2010
    ..The benefits of omega-3 (n-3) long-chain polyunsaturated fatty acids to heart health are well established. Stearidonic acid (SDA, 18:4n-3) may contribute to these benefits...
  26. pmc A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years
    Richard D Antrobus
    The Jenner Institute, University of Oxford, Oxford, United Kingdom
    PLoS ONE 7:e48322. 2012
    ..We assessed the safety and immunogenicity of MVA-NP+M1, a viral-vectored influenza vaccine designed to boost memory T cell responses, in ..
  27. ncbi Safety and efficacy of combining sunitinib with bevacizumab + paclitaxel/carboplatin in non-small cell lung cancer
    Mark A Socinski
    Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA
    J Thorac Oncol 5:354-60. 2010
    ....
  28. ncbi Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level
    R Vieth
    Mount Sinai Hospital, Toronto, Ontario, Canada
    Am J Clin Nutr 73:288-94. 2001
    ..The Food and Nutrition Board of the National Academy of Sciences states that 95 microg vitamin D/d is the lowest observed adverse effect level (LOAEL)...
  29. ncbi Benefits of Water Safety Plans: microbiology, compliance, and public health
    María J Gunnarsdóttir
    Faculty of Civil and Environmental Engineering, University of Iceland, Hjardarhaga 2 6, 107 Reykjavik, Iceland
    Environ Sci Technol 46:7782-9. 2012
    The Water Safety Plan (WSP) methodology, which aims to enhance safety of drinking water supplies, has been recommended by the World Health Organization since 2004. WSPs are now used worldwide and are legally required in several countries...
  30. pmc Perceived crime and traffic safety is related to physical activity among adults in Nigeria
    Adewale L Oyeyemi
    Department of Physiotherapy, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria
    BMC Public Health 12:294. 2012
    Neighborhood safety is inconsistently related to physical activity, but is seldom studied in developing countries. This study examined associations between perceived neighborhood safety and physical activity among Nigerian adults.
  31. ncbi Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults
    Frances H Priddy
    Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    Clin Infect Dis 46:1769-81. 2008
    The safety and immunogenicity of the MRK adenovirus type 5 human immunodeficiency virus type 1 clade B gag/pol/nef vaccine, a replication-incompetent adenovirus type 5-vectored vaccine designed to elicit cell-mediated immunity against ..
  32. pmc Physician attitudes towards pharmacological cognitive enhancement: safety concerns are paramount
    Opeyemi C Banjo
    National Core for Neuroethics, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 5:e14322. 2010
    ..as to the reasons they answered as they did, the most prominent concerns physicians expressed were issues of safety that were not offset by the benefit afforded the individual, even in the face of explicit safety claims...
  33. pmc The relation between neighborhood built environment and walking activity among older adults
    Corey L Nagel
    School of Nursing, Oregon Health and Science University, Portland, OR, USA
    Am J Epidemiol 168:461-8. 2008
    ..These findings suggest that built environment may not play a significant role in whether older adults walk, but, among those who do walk, it is associated with increased levels of activity...
  34. ncbi Safety and efficacy of drug-eluting and bare metal stents: comprehensive meta-analysis of randomized trials and observational studies
    Ajay J Kirtane
    The Cardiovascular Research Foundation, Columbia University Medical Center, 111 E 59th Street, New York, NY 10022, USA
    Circulation 119:3198-206. 2009
    The safety and efficacy of drug-eluting stents (DES) among more generalized "real-world" patients than those enrolled in pivotal randomized controlled trials (RCTs) are controversial...
  35. ncbi Safety and efficacy of adjunctive balloon remodeling during endovascular treatment of intracranial aneurysms: a literature review
    M Shapiro
    Department of Radiology, New York University Langone Medical Center, New York, NY 10016, USA
    AJNR Am J Neuroradiol 29:1777-81. 2008
    ..Nevertheless, there exists concern that adjunctive use of balloon assistance may lead to increased adverse events during aneurysm coiling...
  36. ncbi Long-term safety of loteprednol etabonate 0.2% in the treatment of seasonal and perennial allergic conjunctivitis
    Haroon Ilyas
    Department of Ophthalmology, University of South Florida College of Medicine, Tampa, FL 33613, USA
    Eye Contact Lens 30:10-3. 2004
    To determine the long-term safety of the topical steroid, loteprednol etabonate 0.2%, in the treatment of seasonal and perennial allergic conjunctivitis.
  37. ncbi Fitness of human enteric pathogens on plants and implications for food safety
    Maria T Brandl
    Produce Safety and Microbiology Research Unit, Agricultural Research Services, U S Department of Agriculture, Albany, California 94710, USA
    Annu Rev Phytopathol 44:367-92. 2006
    ....
  38. ncbi Safety issues and prospects for future generations of PPAR modulators
    Anne Rubenstrunk
    GENFIT, F 59006 Loos, France
    Biochim Biophys Acta 1771:1065-81. 2007
    ..However, despite the proven benefits of targeting PPARs, safety concerns have recently led to late stage development failures of various PPAR agonists including novel specific ..
  39. pmc Safety in numbers: more walkers and bicyclists, safer walking and bicycling
    P L Jacobsen
    Public Health Consultant, 4730 Monterey Way, Sacramento, CA 95822, USA
    Inj Prev 9:205-9. 2003
    ..However, three published analyses of collision rates at specific intersections found a non-linear relationship, such that collisions rates declined with increases in the numbers of people walking or bicycling...
  40. ncbi Teamwork and patient safety in dynamic domains of healthcare: a review of the literature
    T Manser
    ETH Zurich, Center for Organizational and Occupational Sciences, Zurich, Switzerland
    Acta Anaesthesiol Scand 53:143-51. 2009
    ..research on teamwork in highly dynamic domains of healthcare such as operating rooms, intensive care, emergency medicine, or trauma and resuscitation teams with a focus on aspects relevant to the quality and safety of patient care.
  41. pmc Exploring associations between physical activity and perceived and objective measures of the built environment
    Aileen P McGinn
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Urban Health 84:162-84. 2007
    ....
  42. ncbi Seeking safety and empathy: adolescent health seeking behavior during pregnancy and early motherhood in central Uganda
    Lynn Atuyambe
    Department of Community Health and Behavioral Sciences, Makerere University School of Public Health, Kampala, Uganda
    J Adolesc 32:781-96. 2009
    ..This will in long-term have an impact on the reduction of morbidity and mortality among adolescent mothers and their newborns...
  43. ncbi Programmed cell death: molecular mechanisms and implications for safety assessment of nanomaterials
    Fernando Torres Andón
    Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Acc Chem Res 46:733-42. 2013
    ..An improved understanding of the complexities of the nanomaterial-induced perturbation of different cell death pathways may allow for a better prediction of the consequences of human exposure...
  44. pmc Patient involvement in patient safety: Protocol for developing an intervention using patient reports of organisational safety and patient incident reporting
    Jane K Ward
    Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford, BD9 6RJ, UK
    BMC Health Serv Res 11:130. 2011
    Patients have the potential to provide a rich source of information on both organisational aspects of safety and patient safety incidents...
  45. pmc Aesthetic amenities and safety hazards associated with walking and bicycling for transportation in New York City
    Gina S Lovasi
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA
    Ann Behav Med 45:S76-85. 2013
    ..One strategy to address health problems related to insufficient physical activity is to examine modifiable neighborhood characteristics associated with active transportation...
  46. ncbi Meta-analysis of the efficacy and safety of adalimumab, etanercept, and infliximab for the treatment of rheumatoid arthritis
    Astrid Wiens
    Pharmacy Practice Research Group, Pharmacy Department, Federal University of Parana, Curitiba, Parana, Brazil
    Pharmacotherapy 30:339-53. 2010
    To evaluate the efficacy and safety of using the anti-tumor necrosis factor-alpha (anti-TNF-alpha) drugs adalimumab, etanercept, and infliximab for the treatment of rheumatoid arthritis.
  47. pmc Defining desirable central nervous system drug space through the alignment of molecular properties, in vitro ADME, and safety attributes
    Travis T Wager
    558 Eastern Point Road, Groton, CT, USA
    ACS Chem Neurosci 1:420-34. 2010
    ..distribution, metabolism, and elimination) attributes, primary pharmacology binding efficiencies, and in vitro safety data for these two sets of compounds...
  48. ncbi Safety of divalproex sodium in migraine prophylaxis: an open-label, long-term study. Long-term Safety of Depakote in Headache Prophylaxis Study Group
    S D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, 111 South 11th Street, Suite 81309, Philadelphia, PA 19107, USA
    Headache 39:633-43. 1999
    ..of long-term divalproex therapy for epilepsy is well established, but little is known about the tolerability or safety of divalproex in long-term migraine prophylaxis...
  49. pmc Students' perceptions of patient safety during the transition from undergraduate to postgraduate training: an activity theory analysis
    Jeantine M de Feijter
    Department of Educational Development and Research, Faculty of Health, Medicine and Life Sciences, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    Adv Health Sci Educ Theory Pract 16:347-58. 2011
    ..medical error can cause harm to patients has raised the attention of the health care community towards patient safety and influenced how and what medical students learn about it...
  50. pmc Smart roadside system for driver assistance and safety warnings: framework and applications
    Jeong Ah Jang
    Vehicle Ship IT Convergence Research Department, ETRI, Electronics and Telecommunications Research Institute, 161 Gajeong dong, Yuseong Gu, Daejeon 305 350, Korea
    Sensors (Basel) 11:7420-36. 2011
    ..This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings...
  51. ncbi Safety criteria for transcranial direct current stimulation (tDCS) in humans
    Michael A Nitsche
    Clin Neurophysiol 114:2220-2; author reply 2222-3. 2003
  52. pmc Physical activity among elderly people in a city population: the influence of neighbourhood level violence and self perceived safety
    Fredrik N Piro
    Institute of General Practice and Community Medicine, PO Box 1130 Blindern, N 0317 Oslo, Norway
    J Epidemiol Community Health 60:626-32. 2006
    ..To study the associations between neighbourhood level violence/fear of violence and physical activity among elderly people, accounting for somatic health...
  53. ncbi Safety of laparoscopy versus laparotomy in early-stage endometrial cancer: a randomised trial
    Marian J E Mourits
    Department of Gynaecology, University Medical Center Groningen, University of Groningen, The Netherlands
    Lancet Oncol 11:763-71. 2010
    ..This study investigated the complication rate of TLH versus TAH in women with early-stage endometrial cancer...
  54. ncbi Critical factors for active transportation to school among low-income and minority students. Evidence from the 2001 National Household Travel Survey
    Noreen C McDonald
    Department of City and Regional Planning, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3140, USA
    Am J Prev Med 34:341-4. 2008
    ..g., Safe Routes to School and the CDC's KidsWalk programs). However, little research has looked at differences in behavior across racial/ethnic and income groups...
  55. ncbi Testing metal-oxide nanomaterials for human safety
    Robert Landsiedel
    BASF SE 67056 Ludwigshafen, Germany
    Adv Mater 22:2601-27. 2010
    ..Enhanced understanding of biophysical properties and cellular effects results in improved testing strategies and enables the selection and production of safe materials...
  56. ncbi Immunogenicity, reactogenicity, and safety of a seven-valent pneumococcal conjugate vaccine (PCV7) concurrently administered with a fully liquid DTPa-IPV-HBV-Hib combination vaccine in healthy infants
    C Olivier
    Hôpital L Mourier, Colombes, France
    Vaccine 26:3142-52. 2008
    To evaluate the immunogenicity, safety and reactogenicity of a seven-valent pneumococcal conjugate vaccine (PCV7) when given concomitantly with a fully liquid DTaP-IPV-HBV-Hib combination vaccine.
  57. ncbi A study of the lagged relationships among safety climate, safety motivation, safety behavior, and accidents at the individual and group levels
    Andrew Neal
    ARC Key Centre for Human Factors and Applied Cognitive Psychology, School of Psychology, University of Queensland, Brisbane, QLD, Australia
    J Appl Psychol 91:946-53. 2006
    The authors measured perceptions of safety climate, motivation, and behavior at 2 time points and linked them to prior and subsequent levels of accidents over a 5-year period...
  58. ncbi Effectiveness and safety of endobronchial ultrasound-transbronchial needle aspiration: a systematic review
    L Varela-Lema
    Galician Agency for Health Technology Assessment, Department of Health, Galician Regional Authority, University of Santiago de Compostela, Santiago de Compostela, Spain
    Eur Respir J 33:1156-64. 2009
    The aim of the present systematic review was to assess the effectiveness and safety of real time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with suspected or known bronchopulmonary carcinoma, ..
  59. ncbi A systematic review and meta-analysis of the efficacy and safety of cyclosporin for the treatment of atopic dermatitis in dogs
    Jean Steffan
    Novartis Animal Health, Basel, Switzerland
    Vet Dermatol 17:3-16. 2006
    ..Treatment duration varied from 2 weeks to 6 months. For safety analysis, data were available from 660 dogs...
  60. pmc Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes
    Markolf Hanefeld
    Zentrum für Klinische Studien, GWT, Technische Universitat Dresden, Dresden, Germany
    Cardiovasc Diabetol 6:20. 2007
    ..The efficacy, safety and tolerability of the alpha-glucosidase inhibitor acarbose have been well-established in a wide range of patient ..
  61. ncbi Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis
    Jean Steffan
    Novartis Animal Health, CH4002 Basel, Switzerland
    J Am Vet Med Assoc 226:1855-63. 2005
    To determine efficacy and safety of cyclosporine in the treatment of atopic dermatitis among dogs in North America.
  62. ncbi Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
    Howard A Burris
    The Sarah Cannon Research Institute, 250 25th Avenue N, Suite 110, Nashville, TN 37203, USA
    J Clin Oncol 23:5305-13. 2005
    This study (EGF10004) assessed the safety/tolerability, pharmacokinetics, and clinical activity of daily oral dosing with lapatinib (GW572016) in patients with ErbB1-expressing and/or ErbB2-overexpressing advanced-stage refractory solid ..
  63. ncbi Efficacy and safety of sitagliptin monotherapy in Japanese patients with type 2 diabetes
    Kenji Nonaka
    Banyu Pharmaceutical Co Ltd, Tokyo, Japan
    Diabetes Res Clin Pract 79:291-8. 2008
    ..01) different relative to the placebo group (-0.7 kg). In this study, once-daily sitagliptin 100mg for 12 weeks improved fasting and postprandial glycemic control and was generally well tolerated in Japanese patients with type 2 diabetes...
  64. ncbi Efficacy and safety of the novel ultrasound contrast agent perflutren (definity) in patients with suboptimal baseline left ventricular echocardiographic images
    D W Kitzman
    Section of Cardiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1045, USA
    Am J Cardiol 86:669-74. 2000
    ..This study examines the safety and efficacy of perflutren, a novel ultrasound contrast agent, for LV cavity opacification and endocardial border ..
  65. ncbi Irradiation as a safety procedure in tissue banking
    Anna Dziedzic-Goclawska
    National Centre of Tissue and Cell Banking, ul Chalubinskiego 5, 02 004, Warsaw, Poland
    Cell Tissue Bank 6:201-19. 2005
    ....
  66. ncbi Microbiological safety of drinking water
    U Szewzyk
    Technical University Berlin, Microbial Ecology Group, Secr OE 5, Berlin, 10587 Germany
    Annu Rev Microbiol 54:81-127. 2000
    ..Results of epidemiological studies together with ecological data are the basis for effective resource protection, water treatment, and risk assessment...
  67. ncbi Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins
    Kathryn H Schmitz
    Division of Clinical Epidemiology University of Pennsylvania 423 Guardian Drive, 9th Floor Blockley Drive, Philadelphia, PA 19072 215 898 0901
    Cancer Epidemiol Biomarkers Prev 14:1672-80. 2005
    This randomized controlled trial assessed the safety and effects of twice-weekly weight training among recent breast cancer survivors. Outcomes included body size and biomarkers hypothesized to link exercise and breast cancer risk.
  68. ncbi Modulation of cortical excitability by weak direct current stimulation--technical, safety and functional aspects
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gotingen, Germany
    Suppl Clin Neurophysiol 56:255-76. 2003
  69. ncbi Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study
    H Buller
    Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Thromb Haemost 6:1313-8. 2008
    ..We conducted a dose-ranging study in patients with deep vein thrombosis...
  70. ncbi Hymenoptera ultra-rush venom immunotherapy (210 min): a safety study and risk factors
    J Birnbaum
    UPRES EA 3287, Service de pneumo allergologie, Hopital Sainte Marguerite, Marseille, France
    Clin Exp Allergy 33:58-64. 2003
    ....
  71. ncbi A systematic review of third-generation hydroxyethyl starch (HES 130/0.4) in resuscitation: safety not adequately addressed
    Christiane S Hartog
    Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich Schiller University, Erlanger Allee 101, D 07747 Jena, Germany
    Anesth Analg 112:635-45. 2011
    ..There are safety concerns with regard to coagulopathy, renal failure, pruritus, tissue storage, and mortality...
  72. ncbi Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
    Stanley B Cohen
    Radiant Research, Dallas, Texas 75235, USA
    Arthritis Rheum 54:2793-806. 2006
    To determine the efficacy and safety of treatment with rituximab plus methotrexate (MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response to anti-tumor necrosis factor (anti-TNF) therapies and to explore ..
  73. pmc Using FDA reports to inform a classification for health information technology safety problems
    Farah Magrabi
    Centre for Health Informatics, Australian Institute for Health Innovation, University of New South Wales, Sydney, Australia
    J Am Med Inform Assoc 19:45-53. 2012
    ..To expand an emerging classification for problems with health information technology (HIT) using reports submitted to the US Food and Drug Administration Manufacturer and User Facility Device Experience (MAUDE) database...
  74. ncbi Active commuting to school: Associations with environment and parental concerns
    Jacqueline Kerr
    Department of Psychology, San Diego State University, San Diego, CA 92103, USA
    Med Sci Sports Exerc 38:787-94. 2006
    ....
  75. ncbi Efficacy and safety of MR imaging with liver-specific contrast agent: U.S. multicenter phase III study
    David A Bluemke
    Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    Radiology 237:89-98. 2005
    To assess prospectively the efficacy and safety of postcontrast magnetic resonance (MR) imaging with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) compared with that of precontrast MR imaging in patients who ..
  76. ncbi Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective
    Melanie Auffan
    Center for the Environmental Implications of NanoTechnology CEINT, Duke University, 121 Hudson Hall, Durham, North Carolina 27707, USA
    Nat Nanotechnol 4:634-41. 2009
    ..in any definition of nanoparticles when making decisions about their regulation for environmental, health and safety reasons...
  77. ncbi Neighborhood environmental factors correlated with walking near home: Using SPACES
    Terri J Pikora
    School of Population Health, The University of Western Australia, Perth, Western Australia, Australia
    Med Sci Sports Exerc 38:708-14. 2006
    ..We examined correlations between physical environmental factors and self-reported walking for recreation and transport near home...
  78. pmc Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: safety and immunogenicity in a phase I clinical study
    A A McCormick
    Large Scale Biology Corporation, 3333 Vaca Valley Parkway, Vacaville, CA 95688, USA
    Proc Natl Acad Sci U S A 105:10131-6. 2008
    ..follicular B cell lymphoma and the results of administering these vaccines to lymphoma patients in a phase I safety and immunogenicity clinical trial...
  79. pmc Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa
    Roger H Brookes
    Bacterial Diseases Programme, Tuberculosis Division, Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    PLoS ONE 3:e2921. 2008
    ..We assessed the safety and immunogenicity of this new vaccine in West African volunteers.
  80. pmc Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates
    Igor S Lukashevich
    Institute of Human Virology, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, MD 21201, United States
    Vaccine 26:5246-54. 2008
    ..that gene expression patterns in ML29-exposed PBMC and control, media-exposed PBMC, clustered together confirming safety profile of the ML29 in non-human primates. The ML29 reassortant is a promising vaccine candidate for Lassa fever.
  81. ncbi Efficacy and safety of tapentadol prolonged release for chronic osteoarthritis pain and low back pain
    Bernd Lange
    Global Development, Grunenthal GmbH, D 52078 Aachen, Germany
    Adv Ther 27:381-99. 2010
    ....
  82. pmc From fear to safety and back: reversal of fear in the human brain
    Daniela Schiller
    Psychology Department, Center for Neural Science, New York University, New York, New York 10003, USA
    J Neurosci 28:11517-25. 2008
    ..To date, research on fear modulation has focused mainly on the shift from fear to safety by using paradigms such as extinction, resulting in a reduction of fear...
  83. ncbi Safety of influenza vaccination during pregnancy
    Pranita D Tamma
    Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Obstet Gynecol 201:547-52. 2009
    ..In this article, we review the evidentiary basis for the recommendation of vaccination of all women who will be pregnant during the influenza season and safety data of influenza vaccination during pregnancy.
  84. ncbi A phase II, open-label, randomized study to assess the efficacy and safety of AZD6244 (ARRY-142886) versus pemetrexed in patients with non-small cell lung cancer who have failed one or two prior chemotherapeutic regimens
    John D Hainsworth
    Sarah Cannon Research Institute, Nashville, TN 37203, USA
    J Thorac Oncol 5:1630-6. 2010
    AZD6244 (ARRY-142886) is a potent, selective MEK inhibitor. This study aimed to evaluate the efficacy and safety of AZD6244 versus pemetrexed as second- or third-line treatment in patients with advanced non-small cell lung cancer (NSCLC).
  85. pmc Antidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns?
    Susan H Busch
    Yale School of Public Health, P O Box 208034, Suite 300, New Haven, CT 06520 8034, USA
    Psychiatr Serv 61:11-6. 2010
    From June 2003 through October 2004, the U.S. Food and Drug Administration (FDA) released five safety warnings related to antidepressant use and the increased risk of suicidality for children...
  86. pmc Feeder layer- and animal product-free culture of neonatal foreskin keratinocytes: improved performance, usability, quality and safety
    Peter De Corte
    Skin and Keratinocyte Bank, Laboratory for Molecular and Cellular Technology, Burn Wound Centre, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium
    Cell Tissue Bank 13:175-89. 2012
    ..These optimisations have significantly increased the performance, usability, quality and safety of our allografts. This paper describes, in detail, our current cryopreserved allograft production process.
  87. ncbi Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction: review of efficacy and safety data in the treatment of patients experiencing chronic pain
    Katri Elina Clemens
    University of Bonn, Malteser Hospital Bonn Rhein Sieg, Centre for Palliative Medicine, Department of Science and Research, Von Hompesch Str 1, D 53123 Bonn, Germany
    Expert Opin Pharmacother 11:297-310. 2010
    ..The combination of the strong opioid oxycodone and the opioid antagonist naloxone has the potential to prevent opioid-induced bowel dysfunction (OIBD) while maintaining analgesic efficacy...
  88. ncbi Efficacy and safety of treatment with incobotulinum toxin A (botulinum neurotoxin type A free from complexing proteins; NT 201) in post-stroke upper limb spasticity
    Petr Kanovsky
    Department of Neurology, Palacky University Medical School University Hospital, IP Pavlova 6, CZ 775 20 Olomouc, Czech Republic
    J Rehabil Med 43:486-92. 2011
    To investigate the efficacy and safety of repeated treatment with incobotulinum toxin A (botulinum neurotoxin type A free from complexing proteins; NT 201) in post-stroke upper limb spasticity.
  89. ncbi The safety and efficacy of travoprost 0.004%/timolol 0.5% fixed combination ophthalmic solution
    Howard S Barnebey
    University of Washington, Ophthalmology, Specialty Eye Care Center, Seattle, 98004, USA
    Am J Ophthalmol 140:1-7. 2005
    To compare the safety and intraocular pressure (IOP)-lowering efficacy of travoprost 0.004%/timolol 0.5% fixed combination ophthalmic solution (Trav/Tim) to its components travoprost 0...
  90. ncbi Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio
    Marja Hedman
    A I Virtanen Institute, University of Kuopio, PO Box 1627, FIN 70211 Kuopio, Finland
    Circulation 107:2677-83. 2003
    ..However, only limited data are available about local VEGF gene transfer given during angioplasty (PTCA) and stenting...
  91. pmc Neighborhood safety, socioeconomic status, and physical activity in older adults
    Reginald D Tucker-Seeley
    Department of Society, Human Development and Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Prev Med 37:207-13. 2009
    ..Yet, the moderating influence of various measures of SES on the association between perceived neighborhood safety and leisure-time physical activity (LTPA) among older adults remains unknown.
  92. ncbi Assessment of postlicensure safety of rotavirus vaccines, with emphasis on intussusception
    Julie E Bines
    Department of Paediatrics, University of Melbourne, Melbourne, Australia
    J Infect Dis 200:S282-90. 2009
    ..In response to a recommendation of the World Health Organization Global Advisory Committee for Vaccine Safety, a standardized approach to the postmarketing surveillance of rotavirus vaccine safety has been developed...
  93. pmc Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study
    Michael Nauck
    Diabeteszentrum Bad Lauterberg, Harz, Germany
    Diabetes Care 32:84-90. 2009
    The efficacy and safety of adding liraglutide (a glucagon-like peptide-1 receptor agonist) to metformin were compared with addition of placebo or glimepiride to metformin in subjects previously treated with oral antidiabetes (OAD) therapy.
  94. ncbi Physical activity levels according to physical and social environmental factors in a sample of adults living in South Brazil
    Tales C Amorim
    Post Graduate Program in Epidemiology, Federal University of Pelotas, Brazil
    J Phys Act Health 7:S204-12. 2010
    ..To evaluate the association between the physical and social environment and physical activity (leisure-time and transport-related) in a population-based sample of adults...
  95. ncbi Laser in situ keratomileusis for myopia and astigmatism: safety and efficacy: a report by the American Academy of Ophthalmology
    Alan Sugar
    Ophthalmic Technology Assessment Committee 2000 2001 Refractive Surgery Panel
    Ophthalmology 109:175-87. 2002
    This document describes laser in situ keratomileusis (LASIK) for myopia and astigmatism and examines the evidence to answer key questions about the efficacy and safety of the procedure.
  96. ncbi Safety and tolerability of frovatriptan in the acute treatment of migraine and prevention of menstrual migraine: Results of a new analysis of data from five previously published studies
    E Anne MacGregor
    The City of London Migraine Clinic, London, United Kingdom
    Gend Med 7:88-108. 2010
    ..Triptans are a recommended first-line treatment for moderate to severe migraine...
  97. ncbi Playing it safe: the influence of neighbourhood safety on children's physical activity. A review
    Alison Carver
    Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Vic, Australia
    Health Place 14:217-27. 2008
    ..Many studies have identified lack of neighbourhood safety as a potential barrier to children's physical activity...
  98. ncbi Bacteriophage therapy of venous leg ulcers in humans: results of a phase I safety trial
    D D Rhoads
    Department of Psychiatry, University of Minnesota, Minneapolis, USA
    J Wound Care 18:237-8, 240-3. 2009
    This phase 1 trial set out to examine the safety of a bacteriophage-based preparation for difficult-to-treat wounds.
  99. ncbi Does simulation improve patient safety? Self-efficacy, competence, operational performance, and patient safety
    Akira Nishisaki
    Division of Critical Care, Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Anesthesiol Clin 25:225-36. 2007
    Simulation training is an essential educational strategy for health care systems to improve patient safety. The strength of simulation training is its suitability for multidisciplinary team training...
  100. ncbi A strategy for describing the biosphere at candidate sites for repositories of nuclear waste: linking ecosystem and landscape modeling
    Tobias Lindborg
    Swedish Nuclear Fuel and Waste Management Co, Stockholm
    Ambio 35:418-24. 2006
    ..paper, we present a strategy to integrate site-specific ecosystem data into spatially explicit models needed for safety assessment studies and the environmental impact assessment...
  101. ncbi Ionophores: their use as ruminant growth promotants and impact on food safety
    T R Callaway
    Food and Feed Safety Research Unit, Southern Plains Agricultural Research Center, 2881 F and B Rd, Agricultural Research Service, USDA, College Station, TX 77845, USA
    Curr Issues Intest Microbiol 4:43-51. 2003
    ..Therefore it appears that ionophores will continue to play a significant role in improving the efficiency of animal production in the future...

Research Grants84

  1. Public Health Model to Promote Safe Elderly Driving
    Sherrilene Classen; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): Older driver safety is a complex phenomenon that extends beyond the person level to multiple systems (e.g., regulatory, policy-making, societal and health care)...
  2. Activity Space Environments, Behaviors, and Body Weight Status in Urban Adults
    Shannon Zenk; Fiscal Year: 2009
    ....
  3. Pharmacotherapy for Minor Depression
    Robert Howland; Fiscal Year: 2004
    ..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..
  4. Inflammatory and Infectious Burden and Risk of Stroke
    Mitchell Elkind; Fiscal Year: 2008
    ..The cross-sectional associations between inflammatory and infectious markers and quantitative MRI abnormalities will also be assessed. ..
  5. Understanding Change in Physical Activity Postpartum
    KELLY EVENSON; Fiscal Year: 2009
    ..This proposal directly addresses the need to better understand multi-level factors involved in physical activity behavior change, RFA #CA-04-009 "Mechanisms of Physical Activity Behavior Change". ..
  6. Spousal communication and cancer prevention behavior
    KELLY EVENSON; Fiscal Year: 2006
    ..The long-term goal of this research is to develop better interventions which help prevent cancer, and other chronic health conditions, by involving spouses in preventive behavior change programs. [unreadable] [unreadable]..
  7. BIOEFFECTS OF GAS BODY ACTIVATION IN MEDICAL ULTRASOUND
    Douglas Miller; Fiscal Year: 2009
    ..This project will examine bioeffects in cells and tissues and show how to safely use ultrasound contrast agents in diagnostic imaging. ..
  8. Alcohol in Aviation and Motor Carriers
    Guohua Li; Fiscal Year: 2010
    ..are to better understand the role of alcohol in aviation and motor carrier accidents and to improve transportation safety. The specific aims are: (1) to determine the point prevalence rates of alcohol violations among safety-sensitive ..
  9. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006
    ..Nationally recognized experts in stroke epidemiology and basic vascular biology will serve as mentors for these studies. ..
  10. Proactive Risk Assessment of Primary Care of the Elderly
    Ben Tzion Karsh; Fiscal Year: 2007
    ..This complexity makes primary care likely to have a high prevalence of safety hazards...
  11. The Value of CPOE in Pediatric Inpatient Units and Its Impact on Safety and Work
    Ben Tzion Karsh; Fiscal Year: 2008
    ..available CPOE systems have realized benefits; with some centers reporting potentially worsened patient safety. One potentially significant aspect of CPOE implementation and use, which may ultimately determine the true ..
  12. ULTRASOUND ENHANCEMENT OF CANCER GENE THERAPY
    Douglas Miller; Fiscal Year: 2003
    ..This research will provide a bridge from the basic research breakthrough to specific therapeutic applications and urgently needed clinical research programs utilizing this novel technology. ..
  13. Bar Coding Technology and Patient and Employee Safety
    Ben Tzion Karsh; Fiscal Year: 2006
    ..human factors engineering systems principles represents a significant step in health care technology and patient safety research for at least four reasons...
  14. BIOEFFECTS OF GAS BODY ACTIVATION IN MEDICAL ULTRASOUND
    Douglas Miller; Fiscal Year: 2001
    ..contrast agents (DUCA), which consist of suspensions of stabilized gas-bodies, presents the most pressing safety issues in medical ultrasound...
  15. Levels of Inflammatory Markers in Treatment of Stroke
    Mitchell Elkind; Fiscal Year: 2008
    ..abstract_text> ..
  16. Violence Against Home Health and Hospice Workers
    Carri Casteel; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  17. Atherogenic Effects of Ambient PM In Susceptible Animals
    Andre Nel; Fiscal Year: 2007
    ..These mice will be exposed to CAPs as discussed in Aims 1 and 2, and select endpoints used to demonstrate the effect on atherosclerotic inflammation and apoptosis. ..
  18. Psychiatric Emergency Room Care: Staff Perspectives
    Alisa Lincoln; Fiscal Year: 2007
    ..abstract_text> ..
  19. Moderating Social Norms Interventions: Field Experiment
    Mark Johnson; Fiscal Year: 2009
    ..This research will help identify factors that might improve the efficacy of social norms interventions. ..
  20. Bloodborne Pathogen Risk in Home Healthcare Workers
    Robyn Gershon; Fiscal Year: 2007
    ..c) organizational variables (availability and adequacy of resources, including the availability of safety devices and other control measures; safety climate, safety training, medical surveillance programs, etc...
  21. Predictors of Adolescent Girls Physical Activity
    KIRSTEN DAVISON; Fiscal Year: 2007
    ..Such information is essential to designing effective prevention programs that promote recommended levels of physical activity during adolescence. [unreadable] [unreadable]..
  22. African American Men Prostate & Colorectal Cancer Belief
    Thomas Arcury; Fiscal Year: 2007
    ..A preliminary framework of the intervention strategy for this R01 application will be developed and evaluated as part of this project. [unreadable] [unreadable]..
  23. Telomere-Mediated Protective Responses in Skin
    Barbara Gilchrest; Fiscal Year: 2007
    ..The studies will also explore the possible therapeutic potential of T-oligos that comparably induce these responses in the absence of actual DNA damage or telomere disruption. ..
  24. VANDERBILT ADULT AIDS CLINICAL TRIALS UNIT
    David Haas; Fiscal Year: 2006
    ..The proposed ACTU will not only enroll patients into ACTG clinical trials, but will provide the ACTG the ability to address important questions concerning AIDS treatment and pathogenesis. ..
  25. DyNADS: A Dynamic Network Analysis Decision Support Tool for Nurse Managers
    Joyce A Verran; Fiscal Year: 2010
    ..unit's current performance, and (b) predict the impact of potential unit innovations to improve targeted safety and quality outcomes...
  26. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2009
    ....
  27. Innovative HCW Training: Infectious Disease Risk
    Robyn Gershon; Fiscal Year: 2002
    ..While, safety training programs are acknowledged as an important part of an overall risk management strategy, there are however, ..
  28. Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial
    Sharon Walsh; Fiscal Year: 2008
    ..A broad array of measures, including measures of drug use, safety, mood, psychosocial functioning, and medication compliance (including riboflavin testing and pill counts) and ..
  29. Evaluation of Novel Treatments for Stimulant Dependence
    Sharon Walsh; Fiscal Year: 2008
    ..a novel agent, aripiprazole, for the treatment of cocaine dependence while simultaneously providing the requisite safety data needed to launch an outpatient clinical trial and exploring the potential efficacy of this agent for smoking ..
  30. Determining the Merit of Self-Rated Health for Risk Prediction
    Karen Desalvo; Fiscal Year: 2008
    ..Karen DeSalvo to launch a successful, independent career in applied health services research focusing on interventions to improve the health of disadvantaged populations. [unreadable] [unreadable] [unreadable] [unreadable]..
  31. Psychosocial Influences on Systemic Lupus
    CAROL GRECO; Fiscal Year: 2008
    ..abstract_text> ..
  32. Modifying the School Environment to Reduce Violence: Suggestions from Students
    SARAH LINDSTROM JOHNSON; Fiscal Year: 2008
    ..Hopefully, this knowledge will assist schools in identifying aspects of their school environment to modify in order to reduce the likelihood of violence. [unreadable] [unreadable] [unreadable]..
  33. CNS Viral Dynamics and Cellular Immunity During AIDS
    David Haas; Fiscal Year: 2009
    ..Characterizing these relationships will expand our knowledge regarding key events that lead to AIDS dementia, and may suggest novel approaches to other immunologic or viral-mediated diseases that affect the brain. ..
  34. IMPACT OF INTIMATE ASSAULT ARREST ON BATTERED WOMENS SAFETY AND SERVICE NEEDS
    MELISSA DICHTER; Fiscal Year: 2007
    ..The empirical literature has yet to identify the impact that being arrested has on a battered woman's safety and service needs; such knowledge is crucial for informing prevention and intervention effort to reduce women'..
  35. ASTHMA CLINICAL RESEARCH NETWORK (ACRN)
    Stephen Peters; Fiscal Year: 2007
    ....
  36. School Environmental Exposures and Measures of the Asthmatic Disease Process
    ELANOR SIDMAN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  37. MELANOMA CONTROL FOR SIBLING OF MELANOMA PATIENTS
    Barbara Gilchrest; Fiscal Year: 2001
    ....
  38. Emotional Mechanisms /Blood-Injection-Injury Phobia
    Olubunmi Olatunji; Fiscal Year: 2004
    ..This research will provide an important contribution to the understanding of the emotions that mediate BII phobia, thus potentially providing a foundation for incorporating effective treatment strategies. ..
  39. Brief Child Safety Interventions in Emergency Department
    Andrea Gielen; Fiscal Year: 2004
    ..We propose to evaluate a theoretically driven and innovative brief intervention for child safety delivered in the Pediatric Emergency Department (PED) of the Johns Hopkins Hospital, which serves a high risk, ..
  40. Casa A Campo: Pesticide Safety for Farmworkers' Families
    Thomas Arcury; Fiscal Year: 2004
    ....
  41. Telomere homolog oligonucleotides for cancer therapy
    Barbara Gilchrest; Fiscal Year: 2004
    ..extend our previous in vitro data, to select an optimal T-oligo for clinical testing, to perform dosing ranging (safety) studies in mice, and then to characterize the therapeutic effects of T-oligos in mouse models of human melanoma ..
  42. Evaluation of California Initiatives to Reduce Violence*
    Corinne Peek Asa; Fiscal Year: 2004
    ..The first initiative was Cal/OSHA's 1993 release of "Guidelines for Security and Safety of Health Care and Community Service Workers...
  43. Violence,PTSD Symptoms & Substance Use
    TAMI SULLIVAN; Fiscal Year: 2004
    ..Data collection will be cross-sectional. ..
  44. Epidemiologic Methods: Resistant Nosocomial Infections
    Marc Lipsitch; Fiscal Year: 2004
    ..This will in turn lead to better practices to reduce the incidence of ARNI. ..
  45. A New Measure of Nursing Home Care Quality
    Marilyn Rantz; Fiscal Year: 2003
    ..abstract_text> ..
  46. MAKING HEAT STRESS ASSESSMENT RELEVANT AGAIN
    Thomas Bernard; Fiscal Year: 2002
    ..In the third year, the emphasis will be on high heat exposures that result in limited work times. This last year will be the test of the heat exchange model and the source of data for the empirical exposure limits. ..
  47. PHYSICIAN INTERVENTION TO IMPROVE DIABETES CARE
    PATRICK O CONNOR; Fiscal Year: 2002
    ..The study will have substantial impact on clinical practice and policy whether the results are positive or negative. If successful, the interventions will be easily disseminated to other primary care practice settings. ..
  48. Prevalence of HIV/STDs among Incarcerated Juveniles
    Angela Robertson; Fiscal Year: 2002
    ..Grant funds will be used to provide STD screening, STD treatment referral, and HIV testing and counseling to juveniles in detention. ..
  49. CONTROL OF IGE MEDIATED PULMONARY INFLAMMATION IN HUMANS
    Stephen Peters; Fiscal Year: 2001
    ....
  50. NIOSH SURVEILLANCE RESEARCH METHODOLOGY
    David Parker; Fiscal Year: 2001
    ..Data analysis will consist of three parts: (1) Descriptive statistics; (2) Timeliness; and (3) Computation of incidence rates by industry. ..
  51. FEAR AND THE ANXIETY DISORDERS: BRAIN AND BEHAVIOR
    Peter Lang; Fiscal Year: 2001
    ..and furthermore, to evaluate memorial, cognitive style, and temperament differences among anxiety disorders, to sharpen differential diagnosis and assess the significance of depressive co-morbidity. ..
  52. COSTS AND BENEFITS OF ALCOHOL SERVICES & INTERVENTIONS
    Michael French; Fiscal Year: 2005
    ..S. as well as abroad, the proposed study holds important potential to assist researchers, policymakers, and program directors with economic evaluation guidelines and "real world" applications. ..
  53. BAC Test Refusals: Are Impaired Driving Laws Threatened?
    Tara Kelley Baker; Fiscal Year: 2006
    ..The results of the study will be useful to state policymakers who face federal legislation that provides incentives for states to increase the severity of the penalties for refusal. [unreadable] [unreadable]..
  54. Evaluating Child Safety Product Dissemination and Educa*
    Andrea Gielen; Fiscal Year: 2005
    ..abstract not provided ..
  55. Proteomics of DEP-induced Oxidative Stress
    Andre Nel; Fiscal Year: 2006
    ..They will also use a display of protein carbonyls to identity oxidatively modified proteins in the BAL fluid. ..
  56. Culture and Mobility Device Use in Older Adults
    Linda Resnik; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  57. 23rd - 27th Annual National Neurotrauma Symposium
    W Dietrich; Fiscal Year: 2005
    ..In addition, there are two sessions for open communications as well as a panel discussions led by Women in Neurotrauma Research. Specific information regarding the organization of future meetings is also discussed. ..
  58. Innovative MRI Research Technology
    PAUL BOTTOMLEY; Fiscal Year: 2005
    ..The work will be implemented at 1 .5T and will directly and positively benefit 21 other funded research grants at this institution, with broad potential benefit to noninvasive imaging in a wide range of patients and diseases. ..
  59. A Dynamic Model of Supervision and Injury Among Children
    Robert Cole; Fiscal Year: 2006
    ..abstract not provided ..
  60. SODIUM IMAGING IN ISCHEMIC HEART DISEASE
    PAUL BOTTOMLEY; Fiscal Year: 2002
    ..The availability of thousands of clinical MRI scanners offers a great opportunity for advancing 23Na MRI as a tool for assessing sodium pump function in human heart disease. ..
  61. Border Girls: AOD Use, Abuse, and Victimization
    Tara Kelley Baker; Fiscal Year: 2009
    ..abstract_text> ..
  62. Certified Safe Farm Evaluating Health Insurance Claims
    Kelley Donham; Fiscal Year: 2006
    Agriculture is one of the most hazardous industries in the US. A recent systematic review of farm safety interventions found little evidence of the interventions being effective...
  63. Evaluating Impact of a Resource Center for Drug Users
    ALEXANDER KRAL; Fiscal Year: 2005
    ..Qualitative interviews will also be conducted with clients (N=30) and staff (N=6), to gain a richer contextual understanding of the impacts of the MNRC. ..
  64. Estrogen and Mechanisms of Cardiomyocyte Protection
    Richard Karas; Fiscal Year: 2009
    ....
  65. MR Studies of Myocardial Creatine Kinase Metabolism
    PAUL BOTTOMLEY; Fiscal Year: 2007
    ....
  66. Correlates of Sexual Risk for HIV/STI Among Women Who Use Methamphetamine
    ALEXANDER KRAL; Fiscal Year: 2008
    ..The proposed study addresses an understudied and important public health issue: MA use among women. [unreadable] [unreadable] [unreadable]..
  67. Qualitative Exploration of Low-Frequency Heroin Injectors Not in Drug Treatment
    ALEXANDER KRAL; Fiscal Year: 2009
    ..An in-depth assessment of low-FHI can inform treatment approaches and expand our knowledge base regarding variations in heroin use among urban poor populations. ..
  68. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2009
    Post-market safety surveillance of medical devices is a complex task compounded by rapid dissemination of new medical technology, lack of standards in data collection, and inadequate passive adverse event reporting mechanisms...
  69. Gastric Tube Placement in Young Children
    Marsha Ellett; Fiscal Year: 2008
    ..Tube placement in children is especially understudied. Increasing the safety of NG/OG feeding in this population requires knowledge development in three areas---predicting the insertion ..
  70. Patient Oriented Research in Pediatric Nutrition
    Nancy Krebs; Fiscal Year: 2008
    ..abstract_text> ..
  71. Social Ecology of Urban Adolescent Substance Abuse: A Multiple Domain Approach
    Michael Mason; Fiscal Year: 2008
    ..Integrated individual, social network and geographical data can serve as a model to direct the development of future innovative substance abuse preventive interventions for urban youth. [unreadable] [unreadable] [unreadable]..
  72. THERAPEUTIC POTENTIAL OF KAPPA-OPIOIDS AGAINST COCAINE
    Sharon Walsh; Fiscal Year: 2002
    ..A series of four controlled laboratory studies are proposed that will systematically evaluate the safety and efficacy of two kappa agonists in humans when given alone and in combination with cocaine...
  73. GIS, ALCOHOL MARKETING, AND ALCOHOL-RELATED OUTCOMES
    Deborah Cohen; Fiscal Year: 2006
    ..Because alcohol marketing is already regulated, if certain marketing techniques are disproportionately associated with alcohol consumption and alcohol-related mortality, the findings can be used to inform public policy. ..
  74. Factors in Drug Dependence
    Sharon Walsh; Fiscal Year: 2005
    ..abstract_text> ..
  75. ALCOHOL OUTLETS, BROKEN WINDOWS, GONORRHEA AND HIV RISK
    Deborah Cohen; Fiscal Year: 2003
    ..The findings will inform future HIV prevention interventions and provide guidance to CBOs as to whether control of alcohol outlets and neighborhood development may enhance the prevention of HIV transmission. ..
  76. Acu/Moxa for Peripheral Neuropathy in Pts with HIV
    JOYCE ANASTASI; Fiscal Year: 2007
    ..The effects of symptom reduction on quality of life will also be examined. In addition, this application originates from an institution with a NIH Center for AIDS Research (CFAR) and a supportive community network. ..
  77. Predicting Driver Safety in Parkinson's Disease
    Ergun Uc; Fiscal Year: 2007
    ..We propose to expand the available knowledge of driving safety in PD by testing a set of hypotheses in experiments that will assess (1) motor function using standardized ..
  78. Energy Absorbing Transit Safe Wheelchair Caster
    LINDA VANROOSMALEN; Fiscal Year: 2004
    ..Upon successful completion of Phase I, FrogLegs will pursue Phase II STTR funding to further develop the transit safe caster-fork assembly for daily use on a variety of wheelchairs. ..
  79. ACTION - A CHF Trial Investigating Outcomes of Exercise
    Steven Keteyian; Fiscal Year: 2007
    The primary aim of the ACTION Trial is to determine the long-term safety and effectiveness of exercise training for New York Heart Association Classes II-IV congestive heart failure patients in addition to standard of care versus a ..
  80. Genetic Predictors of Outcome in Acute MI
    Marc Sabatine; Fiscal Year: 2005
    ..Genomic control will be employed to detect and control for population stratification. Interaction terms will be incorporated into regression models to explore gene-environment and pharmacogenomic interactions. ..
  81. Early Diagnosis of Neonatal Candidiasis
    Daniel Benjamin; Fiscal Year: 2008
    ..abstract_text> ..
  82. Antidepressant Use and Suicide
    Susan Busch; Fiscal Year: 2009
    ..The significance of this project lies in its potential to help clinicians and policymakers assess and manage competing risk and benefit claims. ..