Genomes and Genes
Summary: The health status of the family as a unit including the impact of the health of one member of the family on the family as a unit and on individual family members; also, the impact of family organization or disorganization on the health status of its members.
Publications327 found, 100 shown here
- Risk factors of influenza transmission in householdsCecile Viboud
Epidemiology and Information Sciences, Universite Pierre et Marie Curie, Paris
Br J Gen Pract 54:684-9. 2004..Influenza transmission in households is a subject of renewed interest, as the vaccination of children is currently under debate and antiviral treatments have been approved for prophylactic use...
- 'It looks good on paper': transitions of care between midwives and child and family health nurses in New South WalesCaroline S E Homer
Centre for Midwifery, Child and Family Health, Faculty of Nursing, Midwifery and Health, University of Technology Sydney, Australia
Women Birth 22:64-72. 2009The way in which women and their babies transition from maternity services to the care of child and family health nurses differs across Australia...
- Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their familiesAsem Alkhateeb
Human Medical Genetics Program, University of Colorado Health Sciences Center, Denver, CO, USA
Pigment Cell Res 16:208-14. 2003..These results suggest that genomic analysis of families with generalized vitiligo and this specific constellation of associated autoimmune disorders will be important to identify the mechanisms of genetic susceptibility to autoimmunity...
- Serial intervals and the temporal distribution of secondary infections within households of 2009 pandemic influenza A (H1N1): implications for influenza control recommendationsChristl A Donnelly
Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
Clin Infect Dis 52:S123-30. 2011..These results will inform future recommendations on duration of isolation of individuals with ILI...
- The transmissibility and control of pandemic influenza A (H1N1) virusYang Yang
Center for Statistics and Quantitative Infectious Diseases, Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA 98109, USA
Science 326:729-33. 2009..If a vaccine were available soon enough, vaccination of children, followed by adults, reaching 70% overall coverage, in addition to high-risk and essential workforce groups, could mitigate a severe epidemic...
- Impact of the family health program on infant mortality in Brazilian municipalitiesRosana Aquino
Instituto De Saude Coletiva, Federal University of Bahia, Rua Basílio da Gas n, Canela, CEP 40 110 140 Salvador, Bahia, Brazil
Am J Public Health 99:87-93. 2009We evaluated the effects of the Family Health Program (FHP), a strategy for reorganization of primary health care at a nationwide level in Brazil, on infant mortality at a municipality level.
- National Institutes of Health State-of-the-Science Conference Statement: Family History and Improving HealthAlfred O Berg
University of Washington, Group Health Research Institute, Seattle, Washington, USA
Ann Intern Med 151:872-7. 2009..Thus, it provides a "snapshot in time" of the state of knowledge on the conference topic. When reading the statement, keep in mind that new knowledge is inevitably accumulating through medical research...
- Grief in children and adolescents bereaved by sudden parental deathNadine M Melhem
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
Arch Gen Psychiatry 68:911-9. 2011..Major advances have been made in our understanding of the phenomenology and course of grief in adults. However, little is known about the course of grief in children and adolescents...
- A de novo missense mutation of the FUS gene in a "true" sporadic ALS caseAdriano Chio
ALS Center, Department of Neuroscience, University of Torino, Torino, Italy
Neurobiol Aging 32:553.e23-6. 2011..R521C). This report highlights the importance of screening ALS patients, both familial and sporadic, for FUS mutations and also suggests that de novo mutations is a relevant mechanism underlying sporadic neurodegenerative disease...
- Association of family history with cancer recurrence and survival in patients with gastric cancerMi Ah Han
National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang, Gyeonggi Do, 410 769, Republic of Korea
J Clin Oncol 30:701-8. 2012..Family history of gastric cancer is a major risk factor for the disease. In this study, we investigated the prognoses of patients with gastric cancer with a family history...
- Child and family health nurses' experiences of oral health of preschool children: a qualitative approachAmit Arora
Department of Population Oral Health, The University of Sydney, Sydney, Australia
J Public Health Dent 72:149-55. 2012The objective of this study was to explore Child and Family Health Nurses' work-related experiences of dental disease in young children.
- Lifetime adversity leads to blunted stress axis reactivity: studies from the Oklahoma Family Health Patterns ProjectWilliam R Lovallo
Behavioral Sciences Laboratories, Veterans Affairs Medical Center, 921 NE 13th Street, Oklahoma City, OK 73104, USA
Biol Psychiatry 71:344-9. 2012..We present evidence that adverse experience in childhood and adolescence can alter core components of the stress axis, including cortisol and heart rate reactivity...
- Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history systemLori A Orlando
Department of Medicine, Duke University, 3475 Erwin Rd, Durham, NC 27705, USA
BMC Health Serv Res 11:264. 2011The CDC's Family History Public Health Initiative encourages adoption and increase awareness of family health history...
- Genetic and household determinants of predisposition to human hookworm infection in a Brazilian communityRupert J Quinnell
Institute of Integrative and Comparative Biology, University of Leeds, Leeds, United Kingdom
J Infect Dis 202:954-61. 2010..A significant role for host genetics in determining hookworm infection intensity has also been shown, but the relationship between host genetics and predisposition has not been investigated...
- Risk factors for syphilis in young women attending a family health program in Vitória, BrazilAngelica Espinosa Miranda
Universidade Federal do Espirito Santo, Vitoria, ES, Brasil
An Bras Dermatol 87:76-83. 2012..The high prevalence of STDs among women indicates the need to implement approaching techniques, case detection and prevention of new cases...
- Risk factors for laboratory-confirmed household transmission of pandemic H1N1 2009 infectionDong Hoon Lee
Department of Emergency Medicine, Chung Ang University Medical Center, Yongsan Hospital, Hangangro 3 ga, Yongsan gu, Seoul, Republic of Korea
Am J Infect Control 38:e43-5. 2010..However, antiviral therapy for index cases did not seem to prevent household transmission of pH1N1...
- Pathology of hereditary breast cancerPetra van der Groep
Department of Pathology, University Medical Center Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
Cell Oncol (Dordr) 34:71-88. 2011..However, in still a part of familial hereditary breast cancers no relationship to any of these breast cancer susceptibility genes can be found. Research on new susceptibility genes is therefore ongoing...
- The effect of community and family interventions on young people's physical activity levels: a review of reviews and updated systematic reviewEsther M F van Sluijs
MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
Br J Sports Med 45:914-22. 2011..Next to the school environment, the family and community environment are key for young people's behaviour and for promoting physical activity (PA)...
- Household transmission of 2009 pandemic influenza A (H1N1) virus in the United StatesSimon Cauchemez
Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London
N Engl J Med 361:2619-27. 2009..Risk factors for transmission remain largely uncharacterized. We characterize the risk factors and describe the transmission of the virus within households...
- Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancerKarin Biedermann
Institute of Pathology, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
J Pathol 207:199-206. 2005..Somatic mutations in the gene do not seem to be a very frequent inactivation event and the finding of no clear pathogenic germline mutation rules out Dsg2 as a major gastric cancer predisposition gene...
- Relationship of obesity to depression: a family-based studyC Dong
Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Int J Obes Relat Metab Disord 28:790-5. 2004..To examine the relationship between obesity and depression in a sample of extremely obese individuals and their siblings and parents...
- Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndromeM Kestila
Department of Biochemistry, University of Oulu, Finland
Mol Cell 1:575-82. 1998..The results demonstrate a crucial role for this protein in the development or function of the kidney filtration barrier...
- C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathyVirginie Carmignac
Institut National de la Sante et de la Recherche Médicale U582, Institut de Myologie, Groupe Hospitalier Pitie Salpetriere, France
Ann Neurol 61:340-51. 2007..Our aim was to delineate the phenotype and determine the genetic defects in two consanguineous families with an early-onset, recessive muscle and cardiac disorder...
- Familial autoimmunity as a risk factor for systemic lupus erythematosus and vice versa: a case-control studyR Priori
Divisione di Reumatologia, Dipartimento di Terapia Medica Applicata, Universita degli Studi La Sapienza, Rome, Italy
Lupus 12:735-40. 2003..6; 95%CI 1.9-11.1). A female SLE patient conferred an increased risk of AD to her FDR; this risk is doubled in females (OR 10.3; 95% CI 3.1-34.4)...
- Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial casesRanju Ralhan
Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Cancer Lett 248:1-17. 2007....
- Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)J T McCracken
Department of Psychiatry and Biobehavioral Scienes, UCLA Neuropsychiatric Institute, Mental Retardation Research Center, UCLA School of Medicine, Los Angeles, CA 90024 1759, USA
Mol Psychiatry 5:531-6. 2000..These data add further support for the role of DRD4 variants conferring increased risk for ADHD, and imply that additional studies of DRD4 and other related genes are needed...
- Intrusion: the central problem for family health promotion among children and single mothers after leaving an abusive partnerJudith Wuest
Faculty of Nursing, University of New Brunswick, Fredericton, New Brunswick, Canada
Qual Health Res 13:597-622. 2003....
- Effect of pneumococcal conjugate vaccine on nasopharyngeal colonization among immunized and unimmunized children in a community-randomized trialKatherine L O'Brien
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
J Infect Dis 196:1211-20. 2007..The impact of PCV on nasopharyngeal (NP) colonization is essential to understanding disease effects...
- Can family history be used as a tool for public health and preventive medicine?Paula W Yoon
Office of Genomics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Genet Med 4:304-10. 2002
- Fourteen new cases contribute to the characterization of the 7q11.23 microduplication syndromeNathalie Van der Aa
Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610 Antwerp, Belgium
Eur J Med Genet 52:94-100. 2009..Our patient collection demonstrates that the 7q11.23 microduplication not only causes language delay, but is also associated with congenital anomalies and a recognizable face...
- The health and well-being of caregivers of children with cerebral palsyParminder Raina
Department of Clinical Epidemiology and Biostatistics, McMaster Evidence based Practice Centre, Hamilton, ON, Canada
Pediatrics 115:e626-36. 2005..The primary objective of the current study was to examine, within a single theory-based multidimensional model, the determinants of physical and psychological health of adult caregivers of children with CP...
- Burden of influenza in healthy children and their householdsN Principi
Institute of Paediatrics, University of Milan, Milan, Italy
Arch Dis Child 89:1002-7. 2004..A prospective, multicentre study was conducted to evaluate the burden of laboratory confirmed influenza in healthy children and their household contacts...
- Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohortDonato Alarcon-Segovia
University of Uppsala, Uppsala, Sweden
Arthritis Rheum 52:1138-47. 2005..To determine whether there is familial aggregation of systemic lupus erythematosus (SLE) and/or other autoimmune diseases in SLE patients and to identify clinical differences between patients with and those without familial autoimmunity...
- Childhood obesity treatment: targeting parents exclusively v. parents and childrenMoria Golan
School of Nutritional Sciences, The Hebrew University of Jerusalem, Rehovot, Israel
Br J Nutr 95:1008-15. 2006..These results suggest that omitting the obese child from active participation in the health-centred programme may be beneficial for weight loss and for the promotion of a healthy lifestyle among obese children...
- The R71G BRCA1 is a founder Spanish mutation and leads to aberrant splicing of the transcriptA Vega
Unidad de Medicina Molecular, INGO-SERGAS, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
Hum Mutat 17:520-1. 2001..Our results are consistent with the possibility that these families shared a common ancestry with BRCA1 R71G being a founder mutation of Spanish origin...
- Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear familyLaufey T Amundadottir
deCODE Genetics, Reykjavik, Iceland
PLoS Med 1:e65. 2004....
- Clinical evaluation of idiopathic paroxysmal kinesigenic dyskinesia: new diagnostic criteriaM K Bruno
Department of Neurology, University of California, San Francisco, CA 94143 2922, USA
Neurology 63:2280-7. 2004..Although a genetic basis is suspected in idiopathic cases, the gene has not been discovered. Establishing strict diagnostic criteria will help genetic studies...
- Effect of multicomponent interventions on caregiver burden and depression: the REACH multisite initiative at 6-month follow-upLaura N Gitlin
Community and Homecare Research Division, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Psychol Aging 18:361-74. 2003..034). Also, active interventions were superior to control conditions for Hispanics, nonspouses, and caregivers with lower education. Results suggest interventions should be multicomponent and tailored...
- To tell or not to tell: barriers and facilitators in family communication about genetic riskK Forrest
Department of Public Health, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
Clin Genet 64:317-26. 2003..If genetic counsellors understood how these factors operate in individual families they might be able to identify effective strategies to promote considered decisions and prevent unnecessary emotional distress...
- Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illnessBlair H Smith
Medical Research Institute, University of Dundee, Dundee, UK
Int J Epidemiol 42:689-700. 2013..These features were designed to maximize the power of the resource to identify, replicate or control for genetic factors associated with a wide spectrum of illnesses and risk factors, both now and in the future...
- Relationships between quality of life and family function in caregiverEmiliano Rodríguez-Sánchez
Unidad de investigación del Centro de Salud de La Alamedilla, Salamanca, Espana
BMC Fam Pract 12:19. 2011..The aim of this study is to analyse the relationship between the functionality of the family and the QoL of caregivers of dependent relatives...
- Paroxysmal kinesigenic dyskinesia: cortical or non-cortical originTeun W van Strien
Department of Neurology, Sint Lucas Andreas Hospital, Amsterdam, The Netherlands
Parkinsonism Relat Disord 18:645-8. 2012..The index patient showed interictal EEG focal changes compatible with paroxysmal dystonic movements of his contralateral leg. This might support cortical involvement in PKD...
- Capacity-building in family health: innovative in-service training program for teams in Latin AmericaYves Talbot
Department of Family and Community Medicine, University of Toronto, 263 McCaul St, 4th Floor, Toronto, ON M5T 1W7, Canada
Can Fam Physician 55:613-3.e1-6. 2009..OBJECTIVE OF THE PROGRAM To implement a model of in-service training in primary health care for interdisciplinary teams of primary health care professionals from Brazil and Chile...
- The economic impact of chronic diseases: how do households respond to shocks? Evidence from RussiaDele Olawale Abegunde
World Health Organization, Chronic Diseases and Health Promotion, 20 Avenue Appia, 1211 Geneva, Switzerland
Soc Sci Med 66:2296-307. 2008..These results have implications for policies regarding the financing of treatment and control of chronic diseases in the country studied...
- Family-based interventions for pediatric obesity: methodological and conceptual challenges from family psychologyKatherine M Kitzmann
Department of Psychology, University of Memphis, Memphis, TN 38152, USA
J Fam Psychol 20:175-89. 2006..The authors highlight methodological and conceptual challenges facing researchers in this area and argue for an even broader family focus in family-based interventions for pediatric obesity...
- Psychosocial well-being and functional outcomes in youth with type 1 diabetes 12 years after disease onsetElisabeth A Northam
Department of Psychology, Royal Children s Hospital, Melbourne, Australia
Diabetes Care 33:1430-7. 2010..Type 1 diabetes in youth and community controls were compared on functional outcomes. Relationships were examined between psychosocial variables at diagnosis and functional outcome 12 years later...
- Paternal postpartum depression, its relationship to maternal postpartum depression, and implications for family healthJanice H Goodman
Boston College Connell School of Nursing, Chestnut Hill, Massachusetts 02467, USA
J Adv Nurs 45:26-35. 2004..Much attention has been paid to the problem of postpartum depression in women. However, there is some indication that men also experience depression after the birth of a child, and that paternal depression is linked to maternal depression...
- People with schizophrenia in five countries: conceptual similarities and intercultural differences in family caregivingBob van Wijngaarden
Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
Schizophr Bull 29:573-86. 2003..As long as cultural bias cannot be ruled out, researchers are advised to compose their own national norm groups and use these as a local standard...
- Molecular evidence of perinatal transmission of Bartonella vinsonii subsp. berkhoffii and Bartonella henselae to a childEdward B Breitschwerdt
College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606 1428, USA
J Clin Microbiol 48:2289-93. 2010..Historical and microbiological results support perinatal transmission of Bartonella species in this family. It is of clinical relevance that Bartonella spp. may adversely influence human reproductive performance...
- Autoimmune diseases in patients with multiple sclerosis and their first-degree relatives: a nationwide cohort study in DenmarkN M Nielsen
Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
Mult Scler 14:823-9. 2008..Multiple sclerosis (MS) and other autoimmune diseases might cluster. Our aim was to estimate the relative risk (RR) of other autoimmune diseases among MS patients and their first-degree relatives in a population-based cohort study...
- Caring for and caring about: disentangling the caregiver effect and the family effectAna Bobinac
Department of Health Policy and Management, Institute for Medical Technology Assessment, Erasmus University Rotterdam iBMG iMTA, Rotterdam, The Netherlands
J Health Econ 29:549-56. 2010..Our results, while explorative, indicate that economic evaluations adopting a societal perspective should include both the family and the caregiving effects measured in the relevant individuals...
- Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromesMatthew Taylor
Adult Medical Genetics Program and Division of Cardiology, University of Colorado Denver, Aurora, USA
Circulation 124:876-85. 2011..We evaluated the cardiomyopathy gene titin (TTN) as a candidate ARVC gene because of its proximity to an ARVC locus at position 2q32 and the connection of the titin protein to the transitional junction at intercalated disks...
- The impact of family history on the outcome of patients with colorectal cancer in a veterans' hospitalPing Sheng Kao
Division of Colon and Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, No 201, Section 2, Shih Pai Road, Taipei 11217, Taiwan
Int J Colorectal Dis 24:1249-54. 2009..The purpose of the study was to investigate the impact of a family history (FH) of colorectal cancer (CRC) in first-degree relatives on the outcome of patients with CRC in a veterans' hospital in Taiwan...
- Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorderJoseph Biederman
Pediatric Psychopharmacology Department, Massachusetts General Hospital, Boston, MA, USA
Psychiatry Res 170:199-203. 2009..94) and 5HTTLPR long allele. Our findings suggest that the DRD4 7-repeat allele is associated with a more persistent course of ADHD...
- Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetesValma Harjutsalo
National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Diabetes 53:2449-54. 2004..Although the majority of sibpairs with type 1 diabetes are discordant for DN, its presence in one sibling doubles the risk for the other diabetic siblings...
- How malaria has affected the human genome and what human genetics can teach us about malariaDominic P Kwiatkowski
Wellcome Trust Centre for Human Genetics and University Department of Paediatrics, Oxford, United Kingdom
Am J Hum Genet 77:171-92. 2005....
- Deployment and the use of mental health services among U.S. Army wivesAlyssa J Mansfield
Department of Epidemiology, University of North Carolina, Chapel Hill, USA
N Engl J Med 362:101-9. 2010..Military operations in Iraq and Afghanistan have involved the frequent and extended deployment of military personnel, many of whom are married. The effect of deployment on mental health in military spouses is largely unstudied...
- Long-term effects from a randomized trial of two public health preventive interventions for parental depressionWilliam R Bearslee
Judge Baker Children s Center, Department of Psychiatry, Children s Hospital Boston, Boston, MA 02115, USA
J Fam Psychol 21:703-13. 2007..These findings demonstrate that brief, family-centered preventive interventions for parental depression may contribute to long-term, sustained improvements in family functioning...
- A novel heterozygous deletion within the 3' region of the PAX6 gene causing isolated aniridia in a large family groupFatih Bayrakli
Department of Neurosurgery, Van Military Hospital, Van, Turkey
J Clin Neurosci 16:1610-4. 2009..Our results support the notion that assessing copy number variation of the PAX6 gene itself and also of flanking regions, may contribute to the molecular diagnosis of aniridia...
- Relationship of family caregiver burden with quality of care and psychopathology in a sample of Arab subjects with schizophreniaMuhammad A Zahid
Department of Psychiatry, Faculty of Medicine, Kuwait University P, O, Box 24923, Safat 13110, Kuwait
BMC Psychiatry 10:71. 2010..Questionnaire--IEQ-EU) and caregiver psychic distress on the one hand, and caregiver's/patient's socio-demographics, clinical features and indices of quality of care, on the other hand, compare with the pattern in the literature?..
- Molecular analysis of mucopolysaccharidosis type I in Tunisia: identification of novel mutation and eight Novel polymorphismsLatifa Chkioua
Biochemistry laboratory Farhat Hached Hospital, Street Doctor Moreau, 4000 Sousse, Tunisia
Diagn Pathol 6:39. 2011..The aim of this study was the detection of mutations in the IDUA gene from 12 additional MPS I patients with various clinical phenotypes (severe, 8 cases; intermediate, 3 cases; mild, 1 case)...
- Familial endometrial cancer in female carriers of MSH6 germline mutationsJ Wijnen
Nat Genet 23:142-4. 1999
- Clinical phenotypes of a large Chinese multigenerational kindred with autosomal dominant familial ALS due to Ile149Thr SOD1 gene mutationGardian C Y Fong
Division of Neurology, University Department of Medicine, University of Hong Kong, Hong Kong
Amyotroph Lateral Scler 7:142-9. 2006..Follow-up of the family will be helpful to explore any potential disease markers...
- Stomach cancer risk in gastric cancer relatives: interaction between Helicobacter pylori infection and family history of gastric cancer for the risk of stomach cancerCheol Min Shin
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
J Clin Gastroenterol 44:e34-9. 2010..pylori) infection and family history of gastric cancer in gastric carcinogenesis...
- Identification of Rad51 alteration in patients with bilateral breast cancerM Kato
Department of Molecular Diagnosis, Cancer Institute, Tokyo, Japan
J Hum Genet 45:133-7. 2000..As this alteration was not present in any patients with breast or colon cancer examined, we assume that this missense alteration is likely to be a disease-causing mutation...
- Alpha-tectorin involvement in hearing disabilities: one gene--two phenotypesJ Balciuniene
Unit of Medical Genetics, Department of Genetics and Pathology, Uppsala University, Sweden
Hum Genet 105:211-6. 1999..Another possibility is that the phenotype in the Swedish family is the result of two defective genes...
- FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosisHan Xiang Deng
Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Chicago, IL 60611, USA
Ann Neurol 67:739-48. 2010..The pathogenic mechanism of the mutant FUS-mediated ALS and potential roles of FUS in non-FUS ALS remain to be investigated...
- Multiplex families with multiple system atrophyKenju Hara
Departments of Neurology, Center for Bioresource based Researches, Brain Research Institute, Niigata University, Niigata, Japan
Arch Neurol 64:545-51. 2007..Multiple system atrophy (MSA) has been considered a sporadic disease, without patterns of inheritance...
- Non-syndromic progressive hearing loss DFNA38 is caused by heterozygous missense mutation in the Wolfram syndrome gene WFS1T L Young
Department of Genomic Sciences, University of Washington, Seattle, WA 98195 7720, USA
Hum Mol Genet 10:2509-14. 2001..The possibility that 'mild' mutations in WFS1 might be a cause of non-syndromic deafness in the general population should be explored...
- Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardiaMeiso Hayashi
Service de cardiologie, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Universite Paris Diderot, INSERM U942, Paris, France
Circulation 119:2426-34. 2009....
- Child in hospital: family experiences and expectations of how nurses can promote family healthHanna Hopia
Department of Nursing Science, University of Tampere, Tampere, Finland
J Clin Nurs 14:212-22. 2005This study set out to explore, from the family's point of view, ways in which nursing staff can promote family health during the child's hospital stay.
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysisVivianna M Van Deerlin
Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Lancet Neurol 7:409-16. 2008..Our aim was to investigate whether TARDBP is a candidate disease gene for familial ALS that is not associated with mutations in superoxide dismutase 1 (SOD1)...
- Health-related quality of life (HRQOL) in family members of cancer victims: results from a longitudinal intervention study in Norway and SwedenGerd Inger Ringdal
Department of Psychology, Norwegian University of Science and Technology NTNU, Trondheim, Norway
Palliat Med 18:108-20. 2004..Before we may reach a definitive conclusion on the effects of palliative care programs for the HRQOL of family members, we need further longitudinal intervention studies with large samples...
- Family cluster of Rocky Mountain spotted feverT F Jones
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 28:853-9. 1999..Because hyperendemic foci and family clusters of RMSF can occur, when a case is suspected clinicians should be vigilant for signs and symptoms consistent with R. rickettsii infection in other persons who may have been similarly exposed...
- Family history and colorectal cancer screening: a survey of physician knowledge and practice patternsPaul C Schroy
Department of Medicine, Boston University School of Medicine, Massachusetts, USA
Am J Gastroenterol 97:1031-6. 2002..The objectives of this study were to assess and compare the current knowledge and practice patterns of gastroenterologists and primary care physicians regarding familial risk of CRC...
- A rare variant of the leptin gene has large effects on blood pressure and carotid intima-medial thickness: a study of 1428 individuals in 248 familiesN Gaukrodger
Institute of Human Genetics, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK
J Med Genet 42:474-8. 2005....
- Informing patients of familial diabetes mellitus risk: How do they respond? A cross-sectional surveyNadeem Qureshi
Division of Primary Care, School of Graduate Entry Medicine and Health, University of Nottingham, Derby City General Hospital, Uttoxeter Road, Derby, DE22 3DT, UK
BMC Health Serv Res 8:37. 2008..A strong family history of type 2 diabetes mellitus (DM) confers increased DM risk. This survey analysis determined whether patients who were informed by their doctors of familial DM risk acknowledged that risk and took steps to reduce it...
- Paraoxonase cluster polymorphisms are associated with sporadic ALSM Saeed
Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Neurology 67:771-6. 2006....
- Bestrophin gene mutations in patients with Best vitelliform macular dystrophyG M Caldwell
Department of Cancer Genetics, Roswell Park Cancer Institute, 666 Elm Street, Buffalo, New York 14263, USA
Genomics 58:98-101. 1999..Finally, we have evidence that some mutations are associated with variable expression of the disease, suggesting the involvement of other factors or genes in the disease phenotype...
- Parenting stress in families of children with disabilitiesT B Smith
Department of Counseling Psychology and Special Education, Brigham Young University, Provo, Utah
Am J Orthopsychiatry 71:257-61. 2001..Implications for intervention and for future research are discussed...
- Acquisition of W135 meningococcal carriage in Hajj pilgrims and transmission to household contacts: prospective studyAnnelies Wilder-Smith
Travellers Health and Vaccination Centre, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433
BMJ 325:365-6. 2002
- Mutations in the VMD2 gene are associated with juvenile-onset vitelliform macular dystrophy (Best disease) and adult vitelliform macular dystrophy but not age-related macular degenerationF Kramer
Institut fur Humangenetik, Universitat Wurzburg, Germany
Eur J Hum Genet 8:286-92. 2000..There were no mutations found in the AMD group. In addition, four frequent intragenic polymorphisms did not reveal allelic association of the VMD2 locus with AMD. These data exclude a direct role of VMD2 in the predisposition to AMD...
- Mucopolysaccharidosis I: Alpha-L-Iduronidase mutations in three Tunisian familiesS Laradi
Mount Sinai School of Medicine, New York University, New York, NY 10029, USA
J Inherit Metab Dis 28:1019-26. 2005..The identification of these mutations and their genotype-phenotype correlations should facilitate prenatal diagnosis and counselling for MPS I in Tunisia, where a very high rate of consanguinity exists...
- Prediction of adolescent smoking from family and social risk factors at 5 years, and maternal smoking in pregnancy and at 5 and 14 yearsFrances V O'Callaghan
School of Psychology, Griffith University, Gold Coast, Mater Misericordiae Hospital, Brisbane and The University of Queensland, Australia
Addiction 101:282-90. 2006..The influence of mothers who smoke in pregnancy or continue to smoke at 14 years was also examined...
- SIMPLE mutation analysis in dominant demyelinating Charcot-Marie-Tooth disease: three novel mutationsPhilippe Latour
Neurogénétique, Laboratoire de Biochimie Pédiatrique, Hopital Debrousse, Lyon, France
J Peripher Nerv Syst 11:148-55. 2006..Motor conduction velocities in the median nerve ranked from 16.4 to 32.8 m/s (n = 20). In our series of 968 unrelated dominant demyelinating CMT cases (1992-2005), the percentage of SIMPLE mutations was 0.6 (6/968)...
- Stratification of breast cancer risk in women with atypia: a Mayo cohort studyAmy C Degnim
Division of General Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Clin Oncol 25:2671-7. 2007..Atypical hyperplasia is a well-recognized risk factor for breast cancer, conveying an approximately four-fold increased risk. Data regarding long-term absolute risk and factors for risk stratification are needed...
- SOD1 mutations in amyotrophic lateral sclerosis. Results from a multicenter Italian studyStefania Battistini
Dept of Neuroscience, University of Siena, Siena, Italy
J Neurol 252:782-8. 2005..No SOD1 gene mutations have been identified in SALS cases. Within FALS cases, The most frequent mutation was the G41S identified in four FALS...
- Pneumococcal carriage in children during their first two years: important role of family exposureT Leino
Department of Vaccines, National Public Health Institute, Helsinki, Finland
Pediatr Infect Dis J 20:1022-7. 2001..This study addresses the risk of Pnc carriage by infants 2 to 24 months of age in terms of simultaneous carriage of pneumococcus by family members...
- Going to scale with community-based primary care: an analysis of the family health program and infant mortality in Brazil, 1999-2004James Macinko
University of Pennsylvania, RWJF Health and Society Scholars program, 3641 Locust Walk, Philadelphia, PA 19104, USA
Soc Sci Med 65:2070-80. 2007This article assesses the effects of an integrated community-based primary care program (Brazil's Family Health Program, known as the PSF) on microregional variations in infant mortality (IMR), neonatal mortality, and post-neonatal ..
- Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypesEbun Aganna
Barts and London, Queen Mary s School of Medicine and Dentistry, London, UK
Arthritis Rheum 48:2632-44. 2003..To investigate the prevalence of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among outpatients presenting with recurrent fevers and clinical features consistent with TRAPS...
- Child and family outcomes of a long-term nurse home visitation programme: a randomised controlled trialLynn Kemp
Centre for Health Equity Training Research and Evaluation, School of Public Health and Community Medicine, University of New South Wales, Liverpool Hospital, Liverpool BC, NSW 1871, Australia
Arch Dis Child 96:533-40. 2011..To investigate the impact of a long-term nurse home visiting programme, embedded within a universal child health system, on the health, development and well-being of the child, mother and family...
- Heritability of vasculopathy, autoimmune disease, and fibrosis in systemic sclerosis: a population-based studyTracy Frech
University of Utah, Division of Rheumatology, Department of Medicine, Salt Lake City, UT 84132, USA
Arthritis Rheum 62:2109-16. 2010..To investigate the familiality of systemic sclerosis (SSc) in relation to Raynaud's phenomenon (RP) (a marker of vasculopathy), other autoimmune inflammatory disease, and fibrotic interstitial lung disease (ILD)...
- Variation in cancer risks, by mutation position, in BRCA2 mutation carriersD Thompson
CRC Genetic Epidemiology Unit, Strangeways Research Laboratory, Cambridge, United Kingdom
Am J Hum Genet 68:410-9. 2001..92% (95% CI = 1.20%-38.57%). Possible mechanisms for the variation in cancer risk are suggested by the coincidence of the OCCR with the RAD51-binding domain...
- An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domainsKinya Ishikawa
Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Yushima, Tokyo, Japan
Am J Hum Genet 77:280-96. 2005....
- Characteristics of health information gatherers, disseminators, and blockers within families at risk of hereditary cancer: implications for family health communication interventionsLaura M Koehly
Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Building 31, Room B1B37D, 31 Center Drive MSC 2073, Bethesda, MD 20892, USA
Am J Public Health 99:2203-9. 2009..Given the importance of the dissemination of accurate family history to assess disease risk, we characterized the gatherers, disseminators, and blockers of health information within families at high genetic risk of cancer...
- Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family historyC Goh
Department of Dermatology, Weill Medical College of Cornell University, New York, NY, USA
J Eur Acad Dermatol Venereol 20:1055-60. 2006..Several lines of evidence support a genetic component to alopecia areata (AA), including differences in patients based on severity of AA, associated diseases and family history...
- A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's DiseaseN Abbas
INSERM U289, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
Hum Mol Genet 8:567-74. 1999....
- Household structure and infectious disease transmissionT House
Department of Biological Sciences, University of Warwick, Coventry, UK
Epidemiol Infect 137:654-61. 2009..Since these benefits of childhood vaccination are a product of correlations between household size and number of dependent children in the household, our results are qualitatively robust for a variety of disease scenarios...
- Perspectives on family health, happiness and harmony (3H) among Hong Kong Chinese people: a qualitative studyW W T Lam
School of Public Health, The University of Hong Kong, Hong Kong, China
Health Educ Res 27:767-79. 2012..Harmony is apparently a core element of good family functioning...
- In-frame deletion in the seventh immunoglobulin-like repeat of filamin C in a family with myofibrillar myopathyAlexey Shatunov
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 9404, USA
Eur J Hum Genet 17:656-63. 2009..The study results suggest that the novel p.Val930_Thr933del mutation in filamin C is the cause of MFM but also indicate that filamin C mutations are a comparatively rare cause of MFM...
- Family Health Program and ambulatory care-sensitive conditions in Southern BrazilFúlvio Borges Nedel
Departamento de Medicina Social, Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, RS, Brasil
Rev Saude Publica 42:1041-52. 2008..The objective of the study was to estimate ACSC among patients hospitalized by the Sistema Unico de Saúde (Brazilian Health System)...
- MOLECULAR GENETICS ANALYSES OF MULTIPLEX FAMILIESShirley Hill; Fiscal Year: 2001..The combined resources of our research team will situate us to initiate positional cloning of a gene, should significant positive linkages be found with our Stage I and Stage 11 genotyping endeavors. ..
- Alcoholism Susceptibility Genes in High Density FamiliesShirley Hill; Fiscal Year: 2009..4 cm intervals for all three generations would be combined and linkage analyses performed using the well validated alcoholism phenotype and the well validated childhood diagnoses obtained from the K-SADS. ..
- COGNITIVE/PERSONALITY FACTORS IN RELATIVES OF ALCOHOLICSShirley Hill; Fiscal Year: 2006..New measures will be added to explore non-shared environmental effects in these families where sibling pairs are available for study (N=346 sib pairs). ..
- CAFFEINE INFLUENCES ON EXERCISE AND PSYCHOLOGICAL STRESSWilliam Lovallo; Fiscal Year: 2004..This new information should aid in evaluating caffeine's effects over the span of midlife, a time at which the cardiovascular health of women changes markedly relative to men. ..
- Course of psychopathology in female youth: Analysis with extant longitudinal dataJoseph Biederman; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- BEHAVIORAL MEDICINE: CARDIOVASCULAR DISEASE RESEARCHWilliam Lovallo; Fiscal Year: 2003..U. medical campus. Training will utilize classroom, laboratory, and clinical facilities at several departments and hospitals on campus. ..
- LONGITUDINAL FOLLOW UP OF ADHD GIRLS AND THEIR SIBLINGSJoseph Biederman; Fiscal Year: 2002....
- Collaborative Pediatric Bipolar Disorder ConferenceJoseph Biederman; Fiscal Year: 2007..While the proposed conference does not intend to solve all outstanding problems associated with pediatric bipolar disorder, it will provide a forum to begin formulating a solution. ..
- Adult Outcome of Attention Deficit Hyperactivity DisorderJoseph Biederman; Fiscal Year: 2007..For these reasons, we expect the proposed work to clarify the course and outcome of ADHD. ..
- PREVENTION OF CIGARETTE SMOKING IN ADHD YOUTHJoseph Biederman; Fiscal Year: 2001..Since there are estimated to be 3.5 million children with ADHD and 20% have been shown to be smokers, targeting this group could potentially impact 700,000 children and adolescents. ..
- Genetics of Vulnerability to Antisocial BehaviorKristen Jacobson; Fiscal Year: 2005..abstract_text> ..
- LEVEL OF RESPONSE TO ALCOHOL AND BRAIN FUNCTIONINGMarc A Schuckit; Fiscal Year: 2010..The project will also expand our understanding of the neural substrates of the level of response to alcohol, a key risk factor for the development of alcohol dependence. ..
- A Cognitive Group Treatment for Borderline OutpatientsDonald Black; Fiscal Year: 2005..abstract_text> ..
- Prospective Study: Alcoholic & Control Family OffspringMarc A Schuckit; Fiscal Year: 2010..Our ultimate goal is to identify ways to prevent the escalation of drinking and associated problems in young populations. ..
- A Family-Genetic Study of Pathological GamblingDonald Black; Fiscal Year: 2009..abstract_text> ..
- Genetic contributors to diabetes and dyslipidemia in African AmericansMichele M Sale; Fiscal Year: 2010..We propose applying this proven strategy to identify new therapeutic targets and allow translation to novel diagnostic, prevention, and treatment strategies for type 2 diabetes. ..
- MULTICENTER GENETIC STUDIES OF SCHIZOPHRENIABrien Riley; Fiscal Year: 2007..unreadable] [unreadable]..
- Family Ritual Continuity: Comorbidity Child MH & IllnessMARCIA WINTER; Fiscal Year: 2006..and beliefs are proposed to be related to child mental health through their effects on medical adherence and family health....
- MOLECULAR GENETICS OF SCHIZOPHRENIADonald Black; Fiscal Year: 2006..The goal of the study is to identify one or more SZ susceptibility genes whose subsequent characterization inmolecular and functional studies will elucidate the pathophysiology and treatment of SZ. ..
- FMRI in Pre-Symptomatic PS1-related Alzheimer's DiseaseJohn Ringman; Fiscal Year: 2005..UCI, with its strong dementia research program, growing MRI capabilities and opportunity to collaborate at the nearby UCLA Brain Imaging Center, is an excellent environment for this endeavor. ..
- ESTROGEN, DIET, GENETICS AND ENDOMETRIAL CANCERSara Olson; Fiscal Year: 2005..This study will provide data on genetic susceptibility in endometrial cancer in conjunction with established risk factors, as well as the first epidemiologic data on the more lethal serous and clear cell tumors. ..
- Bupropion VS Placebo to Treat Pathological GamblingDonald Black; Fiscal Year: 2004..abstract_text> ..
- Juvenile Bipolar Disorder and Substance AbuseTimothy E Wilens; Fiscal Year: 2010..Since BPD is identifiable and treatable, findings from the four-year follow-up will provide valuable information to formulate prevention and early intervention strategies. ..
- EFFECTS OF CHANGING SEDENTARY BEHAVIOR IN OBESE CHILDRENLeonard Epstein; Fiscal Year: 2008..Developing a better understanding of why obese youth increase physical activity or decrease energy intake when sedentary behaviors are reduced is important for the treatment of pediatric obesity. [unreadable] [unreadable] [unreadable]..
- Family-Focused Treatment for Bipolar AdolescentsDAVID JAY MIKLOWITZ; Fiscal Year: 2010..At the study's completion, we will have obtained a knowledge base to help develop a best practice model of treatment for BP adolescents that integrates family-focused problem-solving with psychopharmacology. ..
- Prophytactic surgery in carriers of BRCA 1/2 mutationsTimothy R Rebbeck; Fiscal Year: 2010..These studies will motivate future studies of BRCA1/2-associated breast tumor biology, prevention, and treatment. ..
- Heritability of Transitions in Women's Alcohol Use/DependenceCarolyn Sartor; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Temperament and Developmental PsychopathologyDavid Rettew; Fiscal Year: 2008..abstract_text> ..
- Development of Statistical Approaches Allowing for Genetic CovariatesChih Chieh Wu; Fiscal Year: 2008..The Texas Cancer Genetic Consortium, a Cancer Genetic Network regional center, will provide the breast cancer data. [unreadable] [unreadable] [unreadable]..
- Mentor Mothers: A Sustainable Family Intervention in South African TownshipsMary J Rotheram Borus; Fiscal Year: 2010..The intervention's impact will be assessed over 15 months in a design that is a blend of an efficacy and effectiveness trial. ..
- Ethnic difference in prostate cancerTimothy R Rebbeck; Fiscal Year: 2010....
- Interaction of PTEN and CDKN1B in Pca susceptibilityJianfeng Xu; Fiscal Year: 2008..The results from this study are likely to significant advance our knowledge of prostate cancer risk and begin to explore the underlying biological mechanisms for any observed differences. ..
- CVD Risk Perception, Behavioral Support and 25-year SurvivalRobert Gramling; Fiscal Year: 2008..e. DNA testing, advanced imaging) will shape beliefs about personal CVD risk, understanding the long-term implications of risk perception is a crucial and timely public health concern. [unreadable] [unreadable] [unreadable] [unreadable]..
- Consumer Perspectives on Family Involvment in CareAlicia Lucksted; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- School-Based Intervention to Prevent Metabolic SyndromeAlan Delamater; Fiscal Year: 2008..unreadable] [unreadable]..
- Quinolone resistant E coli in long term care facilitiesEbbing Lautenbach; Fiscal Year: 2009..abstract_text> ..
- PROPHYLACTIC COGNITIVE THERAPY FOR DEPRESSIONMichael E Thase; Fiscal Year: 2010....
- REACH-OUT CHICAGO CHILDRENS DIABETES PREVENTION PROJECTDeborah Burnet; Fiscal Year: 2008..unreadable] [unreadable]..
- PSYCHOLOGICAL OUTCOME IN CHILDHOOD CANCER SURVIVORSAnne Kazak; Fiscal Year: 2008..abstract_text> ..
- Exploring strategies to increase school breakfast consumption in middle schoolsKaren Cullen; Fiscal Year: 2007..Improving SB participation may be an important public health environmental intervention with both significant health and academic outcomes. [unreadable] [unreadable] [unreadable]..
- Latino Eye Health: A Communication Strategy for DiabetesSheila West; Fiscal Year: 2007..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
- CHANGING PARENTAL BELIEFS IN PEDIATRICS ONCOLOGYAnne Kazak; Fiscal Year: 2005..If effective, SCCIP-R would provide evidence for the feasibility and importance of providing systemic intervention with families of patients with cancer. ..
- Intermittent Explosive Disorder: A Family StudyEMIL COCCARO; Fiscal Year: 2005..e., relatives of IED probands with and without IED). ..
- Modifying the home T.V. watching environmentLeonard Epstein; Fiscal Year: 2005..abstract_text> ..
- EFFECTS ON CHILDREN OF TREATING MATERNAL DEPRESSIONAnne Riley; Fiscal Year: 2002..This design will enable us to develop sensitive longitudinal models of the way in which changes in aspects of the mother's depression affect the outcomes of the child over time. ..
- EXAMINING THE EFFICACY OF 'PARENTS WHO CARE'KEVIN HAGGERTY; Fiscal Year: 2004....
- Efficacy of Massage Therapy at the End of LifeJean Kutner; Fiscal Year: 2005..Analyses will determine the independent influence of the intervention (a series of massage therapy sessions) on the identified outcomes (pain, physical and emotional symptom distress, quality of life). ..
- HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVMARY ROTHERAM BORUS; Fiscal Year: 2004..abstract_text> ..
- THE SIGNIFICANCE OF FUNGURIA IN HOSPITALIZED PATIENTSLoren Miller; Fiscal Year: 2004....
- Outreach and Treatment for Depression in the Labor ForceRonald Kessler; Fiscal Year: 2005..This is an extremely important opportunity for rapid and widespread dissemination in an area of research where dissemination of positive results has traditionally been a serious problem. ..
- Treatment of Youth Alcohol Abuse and SuicidalityChristianne Esposito Smythers; Fiscal Year: 2007..abstract_text> ..
- ETIOLOGIC HETEROGENEITY IN LATE ONSET BREAST CANCERTimothy Rebbeck; Fiscal Year: 2001..The results of these analyses will be used to attempt to elucidate the complex, multifactorial aetiology of late onset breast cancer. ..
- D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive DisorderEric Storch; Fiscal Year: 2007..Such agents may have utility in improving outcome, reducing premature therapy termination, and targeting patients who have been treatment refractory. [unreadable] [unreadable] [unreadable]..
- Sensible Treatment of Obesity in Rural Youth- STORYDavid Janicke; Fiscal Year: 2006..Findings will provide critical information for planning the R18 RCT. ..
- MAPPING SUSCEPTIBILITY ALLELES FOR BPHWilliam Isaacs; Fiscal Year: 2001....
- PUBLIC ATTITUDES TOWARDS DEATH AND ORGAN PROCUREMENTLaura Siminoff; Fiscal Year: 2001..Finally, a community dialogue will be implemented to interpret and disseminate the findings and provide recommendations to policy makers. ..
- Aging, Acculturation, and Health: Korean American EldersYuri Jang; Fiscal Year: 2005..This study is an important step in expanding our understanding of the unique experiences of minority elders; further research will be developed based on the results from this pilot research. ..
- High Density Association Analysis of Lung CancerChristopher I Amos; Fiscal Year: 2010..We are collaborating with the International Lung Cancer Consortium so that it can further validate our findings for a variety of different populations, in future initiatives. ..
- METHYLPHENIDATE TREATMENT OF ADHD IN CHILDREN WITH TSKenneth Gadow; Fiscal Year: 2004..To evaluate the impact of tic severity and comorbid internalizing and externalizing symptoms on clinical outcome, children with ADHD/+tics will be compared with an additional sample of children with ADHD/-tics at ages 11 and 16 years. ..
- Infant hearing for modulated tonesBarbara Cone Wesson; Fiscal Year: 2003..This research will also result in methods for assessing threshold sensitivity and sound discrimination in infants that can be applied to those at risk for hearing loss or other auditory dysfunction. ..
- Resistant E.coli in Humans and PoultryJames Johnson; Fiscal Year: 2005..Does the research address a current and compelling problem of antimicrobial resistance that is of high public health importance and for which research is needed? [yes]. ..
- Genetic Epidemiology of Parkinson's DiseaseKaren Marder; Fiscal Year: 2008..unreadable] [unreadable]..
- Clinical Impact of Quinolone-Resistant E.coli carriageEbbing Lautenbach; Fiscal Year: 2007..unreadable] [unreadable]..
- Neurobiologic Study of Psychological Distress & DementiaRobert S Wilson; Fiscal Year: 2010....
- Nanoscale approaches to allelic silencing in myocardial disease statesEuan Ashley; Fiscal Year: 2009..This familial condition where the heart grows too thick is the most common cause of sudden death in young people and athletes. ..
- Markers of Risk for Nicotine Dependence in YoungstersUma Rao; Fiscal Year: 2006..Even if only a small subgroup of youngsters at risk for ND can be identified by such means, because of the many direct as well as indirect negative consequences associated with ND, this will be of great public health importance. ..