family health

Summary

Summary: The health status of the family as a unit including the impact of the health of one member of the family on the family as a unit and on individual family members; also, the impact of family organization or disorganization on the health status of its members.

Top Publications

  1. pmc Risk factors of influenza transmission in households
    Cecile Viboud
    Epidemiology and Information Sciences, Universite Pierre et Marie Curie, Paris
    Br J Gen Pract 54:684-9. 2004
  2. ncbi 'It looks good on paper': transitions of care between midwives and child and family health nurses in New South Wales
    Caroline S E Homer
    Centre for Midwifery, Child and Family Health, Faculty of Nursing, Midwifery and Health, University of Technology Sydney, Australia
    Women Birth 22:64-72. 2009
  3. ncbi Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families
    Asem Alkhateeb
    Human Medical Genetics Program, University of Colorado Health Sciences Center, Denver, CO, USA
    Pigment Cell Res 16:208-14. 2003
  4. pmc Serial intervals and the temporal distribution of secondary infections within households of 2009 pandemic influenza A (H1N1): implications for influenza control recommendations
    Christl A Donnelly
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    Clin Infect Dis 52:S123-30. 2011
  5. pmc The transmissibility and control of pandemic influenza A (H1N1) virus
    Yang Yang
    Center for Statistics and Quantitative Infectious Diseases, Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA 98109, USA
    Science 326:729-33. 2009
  6. pmc Impact of the family health program on infant mortality in Brazilian municipalities
    Rosana Aquino
    Instituto De Saude Coletiva, Federal University of Bahia, Rua Basílio da Gas n, Canela, CEP 40 110 140 Salvador, Bahia, Brazil
    Am J Public Health 99:87-93. 2009
  7. ncbi National Institutes of Health State-of-the-Science Conference Statement: Family History and Improving Health
    Alfred O Berg
    University of Washington, Group Health Research Institute, Seattle, Washington, USA
    Ann Intern Med 151:872-7. 2009
  8. pmc Grief in children and adolescents bereaved by sudden parental death
    Nadine M Melhem
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    Arch Gen Psychiatry 68:911-9. 2011
  9. pmc A de novo missense mutation of the FUS gene in a "true" sporadic ALS case
    Adriano Chio
    ALS Center, Department of Neuroscience, University of Torino, Torino, Italy
    Neurobiol Aging 32:553.e23-6. 2011
  10. ncbi Association of family history with cancer recurrence and survival in patients with gastric cancer
    Mi Ah Han
    National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang, Gyeonggi Do, 410 769, Republic of Korea
    J Clin Oncol 30:701-8. 2012

Detail Information

Publications327 found, 100 shown here

  1. pmc Risk factors of influenza transmission in households
    Cecile Viboud
    Epidemiology and Information Sciences, Universite Pierre et Marie Curie, Paris
    Br J Gen Pract 54:684-9. 2004
    ..Influenza transmission in households is a subject of renewed interest, as the vaccination of children is currently under debate and antiviral treatments have been approved for prophylactic use...
  2. ncbi 'It looks good on paper': transitions of care between midwives and child and family health nurses in New South Wales
    Caroline S E Homer
    Centre for Midwifery, Child and Family Health, Faculty of Nursing, Midwifery and Health, University of Technology Sydney, Australia
    Women Birth 22:64-72. 2009
    The way in which women and their babies transition from maternity services to the care of child and family health nurses differs across Australia...
  3. ncbi Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families
    Asem Alkhateeb
    Human Medical Genetics Program, University of Colorado Health Sciences Center, Denver, CO, USA
    Pigment Cell Res 16:208-14. 2003
    ..These results suggest that genomic analysis of families with generalized vitiligo and this specific constellation of associated autoimmune disorders will be important to identify the mechanisms of genetic susceptibility to autoimmunity...
  4. pmc Serial intervals and the temporal distribution of secondary infections within households of 2009 pandemic influenza A (H1N1): implications for influenza control recommendations
    Christl A Donnelly
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    Clin Infect Dis 52:S123-30. 2011
    ..These results will inform future recommendations on duration of isolation of individuals with ILI...
  5. pmc The transmissibility and control of pandemic influenza A (H1N1) virus
    Yang Yang
    Center for Statistics and Quantitative Infectious Diseases, Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA 98109, USA
    Science 326:729-33. 2009
    ..If a vaccine were available soon enough, vaccination of children, followed by adults, reaching 70% overall coverage, in addition to high-risk and essential workforce groups, could mitigate a severe epidemic...
  6. pmc Impact of the family health program on infant mortality in Brazilian municipalities
    Rosana Aquino
    Instituto De Saude Coletiva, Federal University of Bahia, Rua Basílio da Gas n, Canela, CEP 40 110 140 Salvador, Bahia, Brazil
    Am J Public Health 99:87-93. 2009
    We evaluated the effects of the Family Health Program (FHP), a strategy for reorganization of primary health care at a nationwide level in Brazil, on infant mortality at a municipality level.
  7. ncbi National Institutes of Health State-of-the-Science Conference Statement: Family History and Improving Health
    Alfred O Berg
    University of Washington, Group Health Research Institute, Seattle, Washington, USA
    Ann Intern Med 151:872-7. 2009
    ..Thus, it provides a "snapshot in time" of the state of knowledge on the conference topic. When reading the statement, keep in mind that new knowledge is inevitably accumulating through medical research...
  8. pmc Grief in children and adolescents bereaved by sudden parental death
    Nadine M Melhem
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    Arch Gen Psychiatry 68:911-9. 2011
    ..Major advances have been made in our understanding of the phenomenology and course of grief in adults. However, little is known about the course of grief in children and adolescents...
  9. pmc A de novo missense mutation of the FUS gene in a "true" sporadic ALS case
    Adriano Chio
    ALS Center, Department of Neuroscience, University of Torino, Torino, Italy
    Neurobiol Aging 32:553.e23-6. 2011
    ..R521C). This report highlights the importance of screening ALS patients, both familial and sporadic, for FUS mutations and also suggests that de novo mutations is a relevant mechanism underlying sporadic neurodegenerative disease...
  10. ncbi Association of family history with cancer recurrence and survival in patients with gastric cancer
    Mi Ah Han
    National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang, Gyeonggi Do, 410 769, Republic of Korea
    J Clin Oncol 30:701-8. 2012
    ..Family history of gastric cancer is a major risk factor for the disease. In this study, we investigated the prognoses of patients with gastric cancer with a family history...
  11. ncbi Child and family health nurses' experiences of oral health of preschool children: a qualitative approach
    Amit Arora
    Department of Population Oral Health, The University of Sydney, Sydney, Australia
    J Public Health Dent 72:149-55. 2012
    The objective of this study was to explore Child and Family Health Nurses' work-related experiences of dental disease in young children.
  12. pmc Lifetime adversity leads to blunted stress axis reactivity: studies from the Oklahoma Family Health Patterns Project
    William R Lovallo
    Behavioral Sciences Laboratories, Veterans Affairs Medical Center, 921 NE 13th Street, Oklahoma City, OK 73104, USA
    Biol Psychiatry 71:344-9. 2012
    ..We present evidence that adverse experience in childhood and adolescence can alter core components of the stress axis, including cortisol and heart rate reactivity...
  13. pmc Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system
    Lori A Orlando
    Department of Medicine, Duke University, 3475 Erwin Rd, Durham, NC 27705, USA
    BMC Health Serv Res 11:264. 2011
    The CDC's Family History Public Health Initiative encourages adoption and increase awareness of family health history...
  14. pmc Genetic and household determinants of predisposition to human hookworm infection in a Brazilian community
    Rupert J Quinnell
    Institute of Integrative and Comparative Biology, University of Leeds, Leeds, United Kingdom
    J Infect Dis 202:954-61. 2010
    ..A significant role for host genetics in determining hookworm infection intensity has also been shown, but the relationship between host genetics and predisposition has not been investigated...
  15. ncbi Risk factors for syphilis in young women attending a family health program in Vitória, Brazil
    Angelica Espinosa Miranda
    Universidade Federal do Espirito Santo, Vitoria, ES, Brasil
    An Bras Dermatol 87:76-83. 2012
    ..The high prevalence of STDs among women indicates the need to implement approaching techniques, case detection and prevention of new cases...
  16. ncbi Risk factors for laboratory-confirmed household transmission of pandemic H1N1 2009 infection
    Dong Hoon Lee
    Department of Emergency Medicine, Chung Ang University Medical Center, Yongsan Hospital, Hangangro 3 ga, Yongsan gu, Seoul, Republic of Korea
    Am J Infect Control 38:e43-5. 2010
    ..However, antiviral therapy for index cases did not seem to prevent household transmission of pH1N1...
  17. pmc Pathology of hereditary breast cancer
    Petra van der Groep
    Department of Pathology, University Medical Center Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    Cell Oncol (Dordr) 34:71-88. 2011
    ..However, in still a part of familial hereditary breast cancers no relationship to any of these breast cancer susceptibility genes can be found. Research on new susceptibility genes is therefore ongoing...
  18. pmc The effect of community and family interventions on young people's physical activity levels: a review of reviews and updated systematic review
    Esther M F van Sluijs
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Br J Sports Med 45:914-22. 2011
    ..Next to the school environment, the family and community environment are key for young people's behaviour and for promoting physical activity (PA)...
  19. pmc Household transmission of 2009 pandemic influenza A (H1N1) virus in the United States
    Simon Cauchemez
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London
    N Engl J Med 361:2619-27. 2009
    ..Risk factors for transmission remain largely uncharacterized. We characterize the risk factors and describe the transmission of the virus within households...
  20. ncbi Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer
    Karin Biedermann
    Institute of Pathology, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
    J Pathol 207:199-206. 2005
    ..Somatic mutations in the gene do not seem to be a very frequent inactivation event and the finding of no clear pathogenic germline mutation rules out Dsg2 as a major gastric cancer predisposition gene...
  21. ncbi Relationship of obesity to depression: a family-based study
    C Dong
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Int J Obes Relat Metab Disord 28:790-5. 2004
    ..To examine the relationship between obesity and depression in a sample of extremely obese individuals and their siblings and parents...
  22. ncbi Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome
    M Kestila
    Department of Biochemistry, University of Oulu, Finland
    Mol Cell 1:575-82. 1998
    ..The results demonstrate a crucial role for this protein in the development or function of the kidney filtration barrier...
  23. ncbi C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathy
    Virginie Carmignac
    Institut National de la Sante et de la Recherche Médicale U582, Institut de Myologie, Groupe Hospitalier Pitie Salpetriere, France
    Ann Neurol 61:340-51. 2007
    ..Our aim was to delineate the phenotype and determine the genetic defects in two consanguineous families with an early-onset, recessive muscle and cardiac disorder...
  24. ncbi Familial autoimmunity as a risk factor for systemic lupus erythematosus and vice versa: a case-control study
    R Priori
    Divisione di Reumatologia, Dipartimento di Terapia Medica Applicata, Universita degli Studi La Sapienza, Rome, Italy
    Lupus 12:735-40. 2003
    ..6; 95%CI 1.9-11.1). A female SLE patient conferred an increased risk of AD to her FDR; this risk is doubled in females (OR 10.3; 95% CI 3.1-34.4)...
  25. ncbi Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases
    Ranju Ralhan
    Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    Cancer Lett 248:1-17. 2007
    ....
  26. ncbi Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)
    J T McCracken
    Department of Psychiatry and Biobehavioral Scienes, UCLA Neuropsychiatric Institute, Mental Retardation Research Center, UCLA School of Medicine, Los Angeles, CA 90024 1759, USA
    Mol Psychiatry 5:531-6. 2000
    ..These data add further support for the role of DRD4 variants conferring increased risk for ADHD, and imply that additional studies of DRD4 and other related genes are needed...
  27. ncbi Intrusion: the central problem for family health promotion among children and single mothers after leaving an abusive partner
    Judith Wuest
    Faculty of Nursing, University of New Brunswick, Fredericton, New Brunswick, Canada
    Qual Health Res 13:597-622. 2003
    ....
  28. ncbi Effect of pneumococcal conjugate vaccine on nasopharyngeal colonization among immunized and unimmunized children in a community-randomized trial
    Katherine L O'Brien
    Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Infect Dis 196:1211-20. 2007
    ..The impact of PCV on nasopharyngeal (NP) colonization is essential to understanding disease effects...
  29. ncbi Can family history be used as a tool for public health and preventive medicine?
    Paula W Yoon
    Office of Genomics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Genet Med 4:304-10. 2002
  30. ncbi Fourteen new cases contribute to the characterization of the 7q11.23 microduplication syndrome
    Nathalie Van der Aa
    Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610 Antwerp, Belgium
    Eur J Med Genet 52:94-100. 2009
    ..Our patient collection demonstrates that the 7q11.23 microduplication not only causes language delay, but is also associated with congenital anomalies and a recognizable face...
  31. ncbi The health and well-being of caregivers of children with cerebral palsy
    Parminder Raina
    Department of Clinical Epidemiology and Biostatistics, McMaster Evidence based Practice Centre, Hamilton, ON, Canada
    Pediatrics 115:e626-36. 2005
    ..The primary objective of the current study was to examine, within a single theory-based multidimensional model, the determinants of physical and psychological health of adult caregivers of children with CP...
  32. pmc Burden of influenza in healthy children and their households
    N Principi
    Institute of Paediatrics, University of Milan, Milan, Italy
    Arch Dis Child 89:1002-7. 2004
    ..A prospective, multicentre study was conducted to evaluate the burden of laboratory confirmed influenza in healthy children and their household contacts...
  33. ncbi Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort
    Donato Alarcon-Segovia
    University of Uppsala, Uppsala, Sweden
    Arthritis Rheum 52:1138-47. 2005
    ..To determine whether there is familial aggregation of systemic lupus erythematosus (SLE) and/or other autoimmune diseases in SLE patients and to identify clinical differences between patients with and those without familial autoimmunity...
  34. ncbi Childhood obesity treatment: targeting parents exclusively v. parents and children
    Moria Golan
    School of Nutritional Sciences, The Hebrew University of Jerusalem, Rehovot, Israel
    Br J Nutr 95:1008-15. 2006
    ..These results suggest that omitting the obese child from active participation in the health-centred programme may be beneficial for weight loss and for the promotion of a healthy lifestyle among obese children...
  35. ncbi The R71G BRCA1 is a founder Spanish mutation and leads to aberrant splicing of the transcript
    A Vega
    Unidad de Medicina Molecular, INGO-SERGAS, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Hum Mutat 17:520-1. 2001
    ..Our results are consistent with the possibility that these families shared a common ancestry with BRCA1 R71G being a founder mutation of Spanish origin...
  36. pmc Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family
    Laufey T Amundadottir
    deCODE Genetics, Reykjavik, Iceland
    PLoS Med 1:e65. 2004
    ....
  37. ncbi Clinical evaluation of idiopathic paroxysmal kinesigenic dyskinesia: new diagnostic criteria
    M K Bruno
    Department of Neurology, University of California, San Francisco, CA 94143 2922, USA
    Neurology 63:2280-7. 2004
    ..Although a genetic basis is suspected in idiopathic cases, the gene has not been discovered. Establishing strict diagnostic criteria will help genetic studies...
  38. pmc Effect of multicomponent interventions on caregiver burden and depression: the REACH multisite initiative at 6-month follow-up
    Laura N Gitlin
    Community and Homecare Research Division, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Psychol Aging 18:361-74. 2003
    ..034). Also, active interventions were superior to control conditions for Hispanics, nonspouses, and caregivers with lower education. Results suggest interventions should be multicomponent and tailored...
  39. ncbi To tell or not to tell: barriers and facilitators in family communication about genetic risk
    K Forrest
    Department of Public Health, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    Clin Genet 64:317-26. 2003
    ..If genetic counsellors understood how these factors operate in individual families they might be able to identify effective strategies to promote considered decisions and prevent unnecessary emotional distress...
  40. ncbi Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness
    Blair H Smith
    Medical Research Institute, University of Dundee, Dundee, UK
    Int J Epidemiol 42:689-700. 2013
    ..These features were designed to maximize the power of the resource to identify, replicate or control for genetic factors associated with a wide spectrum of illnesses and risk factors, both now and in the future...
  41. pmc Relationships between quality of life and family function in caregiver
    Emiliano Rodríguez-Sánchez
    Unidad de investigación del Centro de Salud de La Alamedilla, Salamanca, Espana
    BMC Fam Pract 12:19. 2011
    ..The aim of this study is to analyse the relationship between the functionality of the family and the QoL of caregivers of dependent relatives...
  42. ncbi Paroxysmal kinesigenic dyskinesia: cortical or non-cortical origin
    Teun W van Strien
    Department of Neurology, Sint Lucas Andreas Hospital, Amsterdam, The Netherlands
    Parkinsonism Relat Disord 18:645-8. 2012
    ..The index patient showed interictal EEG focal changes compatible with paroxysmal dystonic movements of his contralateral leg. This might support cortical involvement in PKD...
  43. pmc Capacity-building in family health: innovative in-service training program for teams in Latin America
    Yves Talbot
    Department of Family and Community Medicine, University of Toronto, 263 McCaul St, 4th Floor, Toronto, ON M5T 1W7, Canada
    Can Fam Physician 55:613-3.e1-6. 2009
    ..OBJECTIVE OF THE PROGRAM To implement a model of in-service training in primary health care for interdisciplinary teams of primary health care professionals from Brazil and Chile...
  44. ncbi The economic impact of chronic diseases: how do households respond to shocks? Evidence from Russia
    Dele Olawale Abegunde
    World Health Organization, Chronic Diseases and Health Promotion, 20 Avenue Appia, 1211 Geneva, Switzerland
    Soc Sci Med 66:2296-307. 2008
    ..These results have implications for policies regarding the financing of treatment and control of chronic diseases in the country studied...
  45. ncbi Family-based interventions for pediatric obesity: methodological and conceptual challenges from family psychology
    Katherine M Kitzmann
    Department of Psychology, University of Memphis, Memphis, TN 38152, USA
    J Fam Psychol 20:175-89. 2006
    ..The authors highlight methodological and conceptual challenges facing researchers in this area and argue for an even broader family focus in family-based interventions for pediatric obesity...
  46. pmc Psychosocial well-being and functional outcomes in youth with type 1 diabetes 12 years after disease onset
    Elisabeth A Northam
    Department of Psychology, Royal Children s Hospital, Melbourne, Australia
    Diabetes Care 33:1430-7. 2010
    ..Type 1 diabetes in youth and community controls were compared on functional outcomes. Relationships were examined between psychosocial variables at diagnosis and functional outcome 12 years later...
  47. ncbi Paternal postpartum depression, its relationship to maternal postpartum depression, and implications for family health
    Janice H Goodman
    Boston College Connell School of Nursing, Chestnut Hill, Massachusetts 02467, USA
    J Adv Nurs 45:26-35. 2004
    ..Much attention has been paid to the problem of postpartum depression in women. However, there is some indication that men also experience depression after the birth of a child, and that paternal depression is linked to maternal depression...
  48. ncbi People with schizophrenia in five countries: conceptual similarities and intercultural differences in family caregiving
    Bob van Wijngaarden
    Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
    Schizophr Bull 29:573-86. 2003
    ..As long as cultural bias cannot be ruled out, researchers are advised to compose their own national norm groups and use these as a local standard...
  49. pmc Molecular evidence of perinatal transmission of Bartonella vinsonii subsp. berkhoffii and Bartonella henselae to a child
    Edward B Breitschwerdt
    College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606 1428, USA
    J Clin Microbiol 48:2289-93. 2010
    ..Historical and microbiological results support perinatal transmission of Bartonella species in this family. It is of clinical relevance that Bartonella spp. may adversely influence human reproductive performance...
  50. ncbi Autoimmune diseases in patients with multiple sclerosis and their first-degree relatives: a nationwide cohort study in Denmark
    N M Nielsen
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Mult Scler 14:823-9. 2008
    ..Multiple sclerosis (MS) and other autoimmune diseases might cluster. Our aim was to estimate the relative risk (RR) of other autoimmune diseases among MS patients and their first-degree relatives in a population-based cohort study...
  51. ncbi Caring for and caring about: disentangling the caregiver effect and the family effect
    Ana Bobinac
    Department of Health Policy and Management, Institute for Medical Technology Assessment, Erasmus University Rotterdam iBMG iMTA, Rotterdam, The Netherlands
    J Health Econ 29:549-56. 2010
    ..Our results, while explorative, indicate that economic evaluations adopting a societal perspective should include both the family and the caregiving effects measured in the relevant individuals...
  52. pmc Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes
    Matthew Taylor
    Adult Medical Genetics Program and Division of Cardiology, University of Colorado Denver, Aurora, USA
    Circulation 124:876-85. 2011
    ..We evaluated the cardiomyopathy gene titin (TTN) as a candidate ARVC gene because of its proximity to an ARVC locus at position 2q32 and the connection of the titin protein to the transitional junction at intercalated disks...
  53. ncbi The impact of family history on the outcome of patients with colorectal cancer in a veterans' hospital
    Ping Sheng Kao
    Division of Colon and Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, No 201, Section 2, Shih Pai Road, Taipei 11217, Taiwan
    Int J Colorectal Dis 24:1249-54. 2009
    ..The purpose of the study was to investigate the impact of a family history (FH) of colorectal cancer (CRC) in first-degree relatives on the outcome of patients with CRC in a veterans' hospital in Taiwan...
  54. pmc Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder
    Joseph Biederman
    Pediatric Psychopharmacology Department, Massachusetts General Hospital, Boston, MA, USA
    Psychiatry Res 170:199-203. 2009
    ..94) and 5HTTLPR long allele. Our findings suggest that the DRD4 7-repeat allele is associated with a more persistent course of ADHD...
  55. ncbi Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetes
    Valma Harjutsalo
    National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 53:2449-54. 2004
    ..Although the majority of sibpairs with type 1 diabetes are discordant for DN, its presence in one sibling doubles the risk for the other diabetic siblings...
  56. pmc How malaria has affected the human genome and what human genetics can teach us about malaria
    Dominic P Kwiatkowski
    Wellcome Trust Centre for Human Genetics and University Department of Paediatrics, Oxford, United Kingdom
    Am J Hum Genet 77:171-92. 2005
    ....
  57. ncbi Deployment and the use of mental health services among U.S. Army wives
    Alyssa J Mansfield
    Department of Epidemiology, University of North Carolina, Chapel Hill, USA
    N Engl J Med 362:101-9. 2010
    ..Military operations in Iraq and Afghanistan have involved the frequent and extended deployment of military personnel, many of whom are married. The effect of deployment on mental health in military spouses is largely unstudied...
  58. ncbi Long-term effects from a randomized trial of two public health preventive interventions for parental depression
    William R Bearslee
    Judge Baker Children s Center, Department of Psychiatry, Children s Hospital Boston, Boston, MA 02115, USA
    J Fam Psychol 21:703-13. 2007
    ..These findings demonstrate that brief, family-centered preventive interventions for parental depression may contribute to long-term, sustained improvements in family functioning...
  59. ncbi A novel heterozygous deletion within the 3' region of the PAX6 gene causing isolated aniridia in a large family group
    Fatih Bayrakli
    Department of Neurosurgery, Van Military Hospital, Van, Turkey
    J Clin Neurosci 16:1610-4. 2009
    ..Our results support the notion that assessing copy number variation of the PAX6 gene itself and also of flanking regions, may contribute to the molecular diagnosis of aniridia...
  60. pmc Relationship of family caregiver burden with quality of care and psychopathology in a sample of Arab subjects with schizophrenia
    Muhammad A Zahid
    Department of Psychiatry, Faculty of Medicine, Kuwait University P, O, Box 24923, Safat 13110, Kuwait
    BMC Psychiatry 10:71. 2010
    ..Questionnaire--IEQ-EU) and caregiver psychic distress on the one hand, and caregiver's/patient's socio-demographics, clinical features and indices of quality of care, on the other hand, compare with the pattern in the literature?..
  61. pmc Molecular analysis of mucopolysaccharidosis type I in Tunisia: identification of novel mutation and eight Novel polymorphisms
    Latifa Chkioua
    Biochemistry laboratory Farhat Hached Hospital, Street Doctor Moreau, 4000 Sousse, Tunisia
    Diagn Pathol 6:39. 2011
    ..The aim of this study was the detection of mutations in the IDUA gene from 12 additional MPS I patients with various clinical phenotypes (severe, 8 cases; intermediate, 3 cases; mild, 1 case)...
  62. ncbi Familial endometrial cancer in female carriers of MSH6 germline mutations
    J Wijnen
    Nat Genet 23:142-4. 1999
  63. ncbi Clinical phenotypes of a large Chinese multigenerational kindred with autosomal dominant familial ALS due to Ile149Thr SOD1 gene mutation
    Gardian C Y Fong
    Division of Neurology, University Department of Medicine, University of Hong Kong, Hong Kong
    Amyotroph Lateral Scler 7:142-9. 2006
    ..Follow-up of the family will be helpful to explore any potential disease markers...
  64. ncbi Stomach cancer risk in gastric cancer relatives: interaction between Helicobacter pylori infection and family history of gastric cancer for the risk of stomach cancer
    Cheol Min Shin
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    J Clin Gastroenterol 44:e34-9. 2010
    ..pylori) infection and family history of gastric cancer in gastric carcinogenesis...
  65. ncbi Identification of Rad51 alteration in patients with bilateral breast cancer
    M Kato
    Department of Molecular Diagnosis, Cancer Institute, Tokyo, Japan
    J Hum Genet 45:133-7. 2000
    ..As this alteration was not present in any patients with breast or colon cancer examined, we assume that this missense alteration is likely to be a disease-causing mutation...
  66. ncbi Alpha-tectorin involvement in hearing disabilities: one gene--two phenotypes
    J Balciuniene
    Unit of Medical Genetics, Department of Genetics and Pathology, Uppsala University, Sweden
    Hum Genet 105:211-6. 1999
    ..Another possibility is that the phenotype in the Swedish family is the result of two defective genes...
  67. ncbi FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
    Han Xiang Deng
    Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Chicago, IL 60611, USA
    Ann Neurol 67:739-48. 2010
    ..The pathogenic mechanism of the mutant FUS-mediated ALS and potential roles of FUS in non-FUS ALS remain to be investigated...
  68. ncbi Multiplex families with multiple system atrophy
    Kenju Hara
    Departments of Neurology, Center for Bioresource based Researches, Brain Research Institute, Niigata University, Niigata, Japan
    Arch Neurol 64:545-51. 2007
    ..Multiple system atrophy (MSA) has been considered a sporadic disease, without patterns of inheritance...
  69. ncbi Non-syndromic progressive hearing loss DFNA38 is caused by heterozygous missense mutation in the Wolfram syndrome gene WFS1
    T L Young
    Department of Genomic Sciences, University of Washington, Seattle, WA 98195 7720, USA
    Hum Mol Genet 10:2509-14. 2001
    ..The possibility that 'mild' mutations in WFS1 might be a cause of non-syndromic deafness in the general population should be explored...
  70. ncbi Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardia
    Meiso Hayashi
    Service de cardiologie, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Universite Paris Diderot, INSERM U942, Paris, France
    Circulation 119:2426-34. 2009
    ....
  71. ncbi Child in hospital: family experiences and expectations of how nurses can promote family health
    Hanna Hopia
    Department of Nursing Science, University of Tampere, Tampere, Finland
    J Clin Nurs 14:212-22. 2005
    This study set out to explore, from the family's point of view, ways in which nursing staff can promote family health during the child's hospital stay.
  72. pmc TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
    Vivianna M Van Deerlin
    Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Lancet Neurol 7:409-16. 2008
    ..Our aim was to investigate whether TARDBP is a candidate disease gene for familial ALS that is not associated with mutations in superoxide dismutase 1 (SOD1)...
  73. ncbi Health-related quality of life (HRQOL) in family members of cancer victims: results from a longitudinal intervention study in Norway and Sweden
    Gerd Inger Ringdal
    Department of Psychology, Norwegian University of Science and Technology NTNU, Trondheim, Norway
    Palliat Med 18:108-20. 2004
    ..Before we may reach a definitive conclusion on the effects of palliative care programs for the HRQOL of family members, we need further longitudinal intervention studies with large samples...
  74. ncbi Family cluster of Rocky Mountain spotted fever
    T F Jones
    Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Clin Infect Dis 28:853-9. 1999
    ..Because hyperendemic foci and family clusters of RMSF can occur, when a case is suspected clinicians should be vigilant for signs and symptoms consistent with R. rickettsii infection in other persons who may have been similarly exposed...
  75. ncbi Family history and colorectal cancer screening: a survey of physician knowledge and practice patterns
    Paul C Schroy
    Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Gastroenterol 97:1031-6. 2002
    ..The objectives of this study were to assess and compare the current knowledge and practice patterns of gastroenterologists and primary care physicians regarding familial risk of CRC...
  76. pmc A rare variant of the leptin gene has large effects on blood pressure and carotid intima-medial thickness: a study of 1428 individuals in 248 families
    N Gaukrodger
    Institute of Human Genetics, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK
    J Med Genet 42:474-8. 2005
    ....
  77. pmc Informing patients of familial diabetes mellitus risk: How do they respond? A cross-sectional survey
    Nadeem Qureshi
    Division of Primary Care, School of Graduate Entry Medicine and Health, University of Nottingham, Derby City General Hospital, Uttoxeter Road, Derby, DE22 3DT, UK
    BMC Health Serv Res 8:37. 2008
    ..A strong family history of type 2 diabetes mellitus (DM) confers increased DM risk. This survey analysis determined whether patients who were informed by their doctors of familial DM risk acknowledged that risk and took steps to reduce it...
  78. ncbi Paraoxonase cluster polymorphisms are associated with sporadic ALS
    M Saeed
    Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Neurology 67:771-6. 2006
    ....
  79. ncbi Bestrophin gene mutations in patients with Best vitelliform macular dystrophy
    G M Caldwell
    Department of Cancer Genetics, Roswell Park Cancer Institute, 666 Elm Street, Buffalo, New York 14263, USA
    Genomics 58:98-101. 1999
    ..Finally, we have evidence that some mutations are associated with variable expression of the disease, suggesting the involvement of other factors or genes in the disease phenotype...
  80. ncbi Parenting stress in families of children with disabilities
    T B Smith
    Department of Counseling Psychology and Special Education, Brigham Young University, Provo, Utah
    Am J Orthopsychiatry 71:257-61. 2001
    ..Implications for intervention and for future research are discussed...
  81. pmc Acquisition of W135 meningococcal carriage in Hajj pilgrims and transmission to household contacts: prospective study
    Annelies Wilder-Smith
    Travellers Health and Vaccination Centre, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433
    BMJ 325:365-6. 2002
  82. ncbi Mutations in the VMD2 gene are associated with juvenile-onset vitelliform macular dystrophy (Best disease) and adult vitelliform macular dystrophy but not age-related macular degeneration
    F Kramer
    Institut fur Humangenetik, Universitat Wurzburg, Germany
    Eur J Hum Genet 8:286-92. 2000
    ..There were no mutations found in the AMD group. In addition, four frequent intragenic polymorphisms did not reveal allelic association of the VMD2 locus with AMD. These data exclude a direct role of VMD2 in the predisposition to AMD...
  83. ncbi Mucopolysaccharidosis I: Alpha-L-Iduronidase mutations in three Tunisian families
    S Laradi
    Mount Sinai School of Medicine, New York University, New York, NY 10029, USA
    J Inherit Metab Dis 28:1019-26. 2005
    ..The identification of these mutations and their genotype-phenotype correlations should facilitate prenatal diagnosis and counselling for MPS I in Tunisia, where a very high rate of consanguinity exists...
  84. ncbi Prediction of adolescent smoking from family and social risk factors at 5 years, and maternal smoking in pregnancy and at 5 and 14 years
    Frances V O'Callaghan
    School of Psychology, Griffith University, Gold Coast, Mater Misericordiae Hospital, Brisbane and The University of Queensland, Australia
    Addiction 101:282-90. 2006
    ..The influence of mothers who smoke in pregnancy or continue to smoke at 14 years was also examined...
  85. ncbi SIMPLE mutation analysis in dominant demyelinating Charcot-Marie-Tooth disease: three novel mutations
    Philippe Latour
    Neurogénétique, Laboratoire de Biochimie Pédiatrique, Hopital Debrousse, Lyon, France
    J Peripher Nerv Syst 11:148-55. 2006
    ..Motor conduction velocities in the median nerve ranked from 16.4 to 32.8 m/s (n = 20). In our series of 968 unrelated dominant demyelinating CMT cases (1992-2005), the percentage of SIMPLE mutations was 0.6 (6/968)...
  86. ncbi Stratification of breast cancer risk in women with atypia: a Mayo cohort study
    Amy C Degnim
    Division of General Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Oncol 25:2671-7. 2007
    ..Atypical hyperplasia is a well-recognized risk factor for breast cancer, conveying an approximately four-fold increased risk. Data regarding long-term absolute risk and factors for risk stratification are needed...
  87. ncbi SOD1 mutations in amyotrophic lateral sclerosis. Results from a multicenter Italian study
    Stefania Battistini
    Dept of Neuroscience, University of Siena, Siena, Italy
    J Neurol 252:782-8. 2005
    ..No SOD1 gene mutations have been identified in SALS cases. Within FALS cases, The most frequent mutation was the G41S identified in four FALS...
  88. ncbi Pneumococcal carriage in children during their first two years: important role of family exposure
    T Leino
    Department of Vaccines, National Public Health Institute, Helsinki, Finland
    Pediatr Infect Dis J 20:1022-7. 2001
    ..This study addresses the risk of Pnc carriage by infants 2 to 24 months of age in terms of simultaneous carriage of pneumococcus by family members...
  89. ncbi Going to scale with community-based primary care: an analysis of the family health program and infant mortality in Brazil, 1999-2004
    James Macinko
    University of Pennsylvania, RWJF Health and Society Scholars program, 3641 Locust Walk, Philadelphia, PA 19104, USA
    Soc Sci Med 65:2070-80. 2007
    This article assesses the effects of an integrated community-based primary care program (Brazil's Family Health Program, known as the PSF) on microregional variations in infant mortality (IMR), neonatal mortality, and post-neonatal ..
  90. ncbi Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes
    Ebun Aganna
    Barts and London, Queen Mary s School of Medicine and Dentistry, London, UK
    Arthritis Rheum 48:2632-44. 2003
    ..To investigate the prevalence of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among outpatients presenting with recurrent fevers and clinical features consistent with TRAPS...
  91. ncbi Child and family outcomes of a long-term nurse home visitation programme: a randomised controlled trial
    Lynn Kemp
    Centre for Health Equity Training Research and Evaluation, School of Public Health and Community Medicine, University of New South Wales, Liverpool Hospital, Liverpool BC, NSW 1871, Australia
    Arch Dis Child 96:533-40. 2011
    ..To investigate the impact of a long-term nurse home visiting programme, embedded within a universal child health system, on the health, development and well-being of the child, mother and family...
  92. pmc Heritability of vasculopathy, autoimmune disease, and fibrosis in systemic sclerosis: a population-based study
    Tracy Frech
    University of Utah, Division of Rheumatology, Department of Medicine, Salt Lake City, UT 84132, USA
    Arthritis Rheum 62:2109-16. 2010
    ..To investigate the familiality of systemic sclerosis (SSc) in relation to Raynaud's phenomenon (RP) (a marker of vasculopathy), other autoimmune inflammatory disease, and fibrotic interstitial lung disease (ILD)...
  93. pmc Variation in cancer risks, by mutation position, in BRCA2 mutation carriers
    D Thompson
    CRC Genetic Epidemiology Unit, Strangeways Research Laboratory, Cambridge, United Kingdom
    Am J Hum Genet 68:410-9. 2001
    ..92% (95% CI = 1.20%-38.57%). Possible mechanisms for the variation in cancer risk are suggested by the coincidence of the OCCR with the RAD51-binding domain...
  94. pmc An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domains
    Kinya Ishikawa
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Yushima, Tokyo, Japan
    Am J Hum Genet 77:280-96. 2005
    ....
  95. pmc Characteristics of health information gatherers, disseminators, and blockers within families at risk of hereditary cancer: implications for family health communication interventions
    Laura M Koehly
    Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Building 31, Room B1B37D, 31 Center Drive MSC 2073, Bethesda, MD 20892, USA
    Am J Public Health 99:2203-9. 2009
    ..Given the importance of the dissemination of accurate family history to assess disease risk, we characterized the gatherers, disseminators, and blockers of health information within families at high genetic risk of cancer...
  96. ncbi Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history
    C Goh
    Department of Dermatology, Weill Medical College of Cornell University, New York, NY, USA
    J Eur Acad Dermatol Venereol 20:1055-60. 2006
    ..Several lines of evidence support a genetic component to alopecia areata (AA), including differences in patients based on severity of AA, associated diseases and family history...
  97. ncbi A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
    N Abbas
    INSERM U289, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Hum Mol Genet 8:567-74. 1999
    ....
  98. pmc Household structure and infectious disease transmission
    T House
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Epidemiol Infect 137:654-61. 2009
    ..Since these benefits of childhood vaccination are a product of correlations between household size and number of dependent children in the household, our results are qualitatively robust for a variety of disease scenarios...
  99. ncbi Perspectives on family health, happiness and harmony (3H) among Hong Kong Chinese people: a qualitative study
    W W T Lam
    School of Public Health, The University of Hong Kong, Hong Kong, China
    Health Educ Res 27:767-79. 2012
    ..Harmony is apparently a core element of good family functioning...
  100. pmc In-frame deletion in the seventh immunoglobulin-like repeat of filamin C in a family with myofibrillar myopathy
    Alexey Shatunov
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 9404, USA
    Eur J Hum Genet 17:656-63. 2009
    ..The study results suggest that the novel p.Val930_Thr933del mutation in filamin C is the cause of MFM but also indicate that filamin C mutations are a comparatively rare cause of MFM...
  101. ncbi Family Health Program and ambulatory care-sensitive conditions in Southern Brazil
    Fúlvio Borges Nedel
    Departamento de Medicina Social, Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, RS, Brasil
    Rev Saude Publica 42:1041-52. 2008
    ..The objective of the study was to estimate ACSC among patients hospitalized by the Sistema Unico de Saúde (Brazilian Health System)...

Research Grants68

  1. MOLECULAR GENETICS ANALYSES OF MULTIPLEX FAMILIES
    Shirley Hill; Fiscal Year: 2001
    ..The combined resources of our research team will situate us to initiate positional cloning of a gene, should significant positive linkages be found with our Stage I and Stage 11 genotyping endeavors. ..
  2. Alcoholism Susceptibility Genes in High Density Families
    Shirley Hill; Fiscal Year: 2009
    ..4 cm intervals for all three generations would be combined and linkage analyses performed using the well validated alcoholism phenotype and the well validated childhood diagnoses obtained from the K-SADS. ..
  3. COGNITIVE/PERSONALITY FACTORS IN RELATIVES OF ALCOHOLICS
    Shirley Hill; Fiscal Year: 2006
    ..New measures will be added to explore non-shared environmental effects in these families where sibling pairs are available for study (N=346 sib pairs). ..
  4. CAFFEINE INFLUENCES ON EXERCISE AND PSYCHOLOGICAL STRESS
    William Lovallo; Fiscal Year: 2004
    ..This new information should aid in evaluating caffeine's effects over the span of midlife, a time at which the cardiovascular health of women changes markedly relative to men. ..
  5. Course of psychopathology in female youth: Analysis with extant longitudinal data
    Joseph Biederman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  6. BEHAVIORAL MEDICINE: CARDIOVASCULAR DISEASE RESEARCH
    William Lovallo; Fiscal Year: 2003
    ..U. medical campus. Training will utilize classroom, laboratory, and clinical facilities at several departments and hospitals on campus. ..
  7. LONGITUDINAL FOLLOW UP OF ADHD GIRLS AND THEIR SIBLINGS
    Joseph Biederman; Fiscal Year: 2002
    ....
  8. Collaborative Pediatric Bipolar Disorder Conference
    Joseph Biederman; Fiscal Year: 2007
    ..While the proposed conference does not intend to solve all outstanding problems associated with pediatric bipolar disorder, it will provide a forum to begin formulating a solution. ..
  9. Adult Outcome of Attention Deficit Hyperactivity Disorder
    Joseph Biederman; Fiscal Year: 2007
    ..For these reasons, we expect the proposed work to clarify the course and outcome of ADHD. ..
  10. PREVENTION OF CIGARETTE SMOKING IN ADHD YOUTH
    Joseph Biederman; Fiscal Year: 2001
    ..Since there are estimated to be 3.5 million children with ADHD and 20% have been shown to be smokers, targeting this group could potentially impact 700,000 children and adolescents. ..
  11. Genetics of Vulnerability to Antisocial Behavior
    Kristen Jacobson; Fiscal Year: 2005
    ..abstract_text> ..
  12. LEVEL OF RESPONSE TO ALCOHOL AND BRAIN FUNCTIONING
    Marc A Schuckit; Fiscal Year: 2010
    ..The project will also expand our understanding of the neural substrates of the level of response to alcohol, a key risk factor for the development of alcohol dependence. ..
  13. A Cognitive Group Treatment for Borderline Outpatients
    Donald Black; Fiscal Year: 2005
    ..abstract_text> ..
  14. Prospective Study: Alcoholic & Control Family Offspring
    Marc A Schuckit; Fiscal Year: 2010
    ..Our ultimate goal is to identify ways to prevent the escalation of drinking and associated problems in young populations. ..
  15. A Family-Genetic Study of Pathological Gambling
    Donald Black; Fiscal Year: 2009
    ..abstract_text> ..
  16. Genetic contributors to diabetes and dyslipidemia in African Americans
    Michele M Sale; Fiscal Year: 2010
    ..We propose applying this proven strategy to identify new therapeutic targets and allow translation to novel diagnostic, prevention, and treatment strategies for type 2 diabetes. ..
  17. MULTICENTER GENETIC STUDIES OF SCHIZOPHRENIA
    Brien Riley; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  18. Family Ritual Continuity: Comorbidity Child MH & Illness
    MARCIA WINTER; Fiscal Year: 2006
    ..and beliefs are proposed to be related to child mental health through their effects on medical adherence and family health....
  19. MOLECULAR GENETICS OF SCHIZOPHRENIA
    Donald Black; Fiscal Year: 2006
    ..The goal of the study is to identify one or more SZ susceptibility genes whose subsequent characterization inmolecular and functional studies will elucidate the pathophysiology and treatment of SZ. ..
  20. FMRI in Pre-Symptomatic PS1-related Alzheimer's Disease
    John Ringman; Fiscal Year: 2005
    ..UCI, with its strong dementia research program, growing MRI capabilities and opportunity to collaborate at the nearby UCLA Brain Imaging Center, is an excellent environment for this endeavor. ..
  21. ESTROGEN, DIET, GENETICS AND ENDOMETRIAL CANCER
    Sara Olson; Fiscal Year: 2005
    ..This study will provide data on genetic susceptibility in endometrial cancer in conjunction with established risk factors, as well as the first epidemiologic data on the more lethal serous and clear cell tumors. ..
  22. Bupropion VS Placebo to Treat Pathological Gambling
    Donald Black; Fiscal Year: 2004
    ..abstract_text> ..
  23. Juvenile Bipolar Disorder and Substance Abuse
    Timothy E Wilens; Fiscal Year: 2010
    ..Since BPD is identifiable and treatable, findings from the four-year follow-up will provide valuable information to formulate prevention and early intervention strategies. ..
  24. EFFECTS OF CHANGING SEDENTARY BEHAVIOR IN OBESE CHILDREN
    Leonard Epstein; Fiscal Year: 2008
    ..Developing a better understanding of why obese youth increase physical activity or decrease energy intake when sedentary behaviors are reduced is important for the treatment of pediatric obesity. [unreadable] [unreadable] [unreadable]..
  25. Family-Focused Treatment for Bipolar Adolescents
    DAVID JAY MIKLOWITZ; Fiscal Year: 2010
    ..At the study's completion, we will have obtained a knowledge base to help develop a best practice model of treatment for BP adolescents that integrates family-focused problem-solving with psychopharmacology. ..
  26. Prophytactic surgery in carriers of BRCA 1/2 mutations
    Timothy R Rebbeck; Fiscal Year: 2010
    ..These studies will motivate future studies of BRCA1/2-associated breast tumor biology, prevention, and treatment. ..
  27. Heritability of Transitions in Women's Alcohol Use/Dependence
    Carolyn Sartor; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  28. Temperament and Developmental Psychopathology
    David Rettew; Fiscal Year: 2008
    ..abstract_text> ..
  29. Development of Statistical Approaches Allowing for Genetic Covariates
    Chih Chieh Wu; Fiscal Year: 2008
    ..The Texas Cancer Genetic Consortium, a Cancer Genetic Network regional center, will provide the breast cancer data. [unreadable] [unreadable] [unreadable]..
  30. Mentor Mothers: A Sustainable Family Intervention in South African Townships
    Mary J Rotheram Borus; Fiscal Year: 2010
    ..The intervention's impact will be assessed over 15 months in a design that is a blend of an efficacy and effectiveness trial. ..
  31. Ethnic difference in prostate cancer
    Timothy R Rebbeck; Fiscal Year: 2010
    ....
  32. Interaction of PTEN and CDKN1B in Pca susceptibility
    Jianfeng Xu; Fiscal Year: 2008
    ..The results from this study are likely to significant advance our knowledge of prostate cancer risk and begin to explore the underlying biological mechanisms for any observed differences. ..
  33. CVD Risk Perception, Behavioral Support and 25-year Survival
    Robert Gramling; Fiscal Year: 2008
    ..e. DNA testing, advanced imaging) will shape beliefs about personal CVD risk, understanding the long-term implications of risk perception is a crucial and timely public health concern. [unreadable] [unreadable] [unreadable] [unreadable]..
  34. Consumer Perspectives on Family Involvment in Care
    Alicia Lucksted; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  35. School-Based Intervention to Prevent Metabolic Syndrome
    Alan Delamater; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  36. Quinolone resistant E coli in long term care facilities
    Ebbing Lautenbach; Fiscal Year: 2009
    ..abstract_text> ..
  37. PROPHYLACTIC COGNITIVE THERAPY FOR DEPRESSION
    Michael E Thase; Fiscal Year: 2010
    ....
  38. REACH-OUT CHICAGO CHILDRENS DIABETES PREVENTION PROJECT
    Deborah Burnet; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  39. PSYCHOLOGICAL OUTCOME IN CHILDHOOD CANCER SURVIVORS
    Anne Kazak; Fiscal Year: 2008
    ..abstract_text> ..
  40. Exploring strategies to increase school breakfast consumption in middle schools
    Karen Cullen; Fiscal Year: 2007
    ..Improving SB participation may be an important public health environmental intervention with both significant health and academic outcomes. [unreadable] [unreadable] [unreadable]..
  41. Latino Eye Health: A Communication Strategy for Diabetes
    Sheila West; Fiscal Year: 2007
    ..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
  42. CHANGING PARENTAL BELIEFS IN PEDIATRICS ONCOLOGY
    Anne Kazak; Fiscal Year: 2005
    ..If effective, SCCIP-R would provide evidence for the feasibility and importance of providing systemic intervention with families of patients with cancer. ..
  43. Intermittent Explosive Disorder: A Family Study
    EMIL COCCARO; Fiscal Year: 2005
    ..e., relatives of IED probands with and without IED). ..
  44. Modifying the home T.V. watching environment
    Leonard Epstein; Fiscal Year: 2005
    ..abstract_text> ..
  45. EFFECTS ON CHILDREN OF TREATING MATERNAL DEPRESSION
    Anne Riley; Fiscal Year: 2002
    ..This design will enable us to develop sensitive longitudinal models of the way in which changes in aspects of the mother's depression affect the outcomes of the child over time. ..
  46. EXAMINING THE EFFICACY OF 'PARENTS WHO CARE'
    KEVIN HAGGERTY; Fiscal Year: 2004
    ....
  47. Efficacy of Massage Therapy at the End of Life
    Jean Kutner; Fiscal Year: 2005
    ..Analyses will determine the independent influence of the intervention (a series of massage therapy sessions) on the identified outcomes (pain, physical and emotional symptom distress, quality of life). ..
  48. HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIV
    MARY ROTHERAM BORUS; Fiscal Year: 2004
    ..abstract_text> ..
  49. THE SIGNIFICANCE OF FUNGURIA IN HOSPITALIZED PATIENTS
    Loren Miller; Fiscal Year: 2004
    ....
  50. Outreach and Treatment for Depression in the Labor Force
    Ronald Kessler; Fiscal Year: 2005
    ..This is an extremely important opportunity for rapid and widespread dissemination in an area of research where dissemination of positive results has traditionally been a serious problem. ..
  51. Treatment of Youth Alcohol Abuse and Suicidality
    Christianne Esposito Smythers; Fiscal Year: 2007
    ..abstract_text> ..
  52. ETIOLOGIC HETEROGENEITY IN LATE ONSET BREAST CANCER
    Timothy Rebbeck; Fiscal Year: 2001
    ..The results of these analyses will be used to attempt to elucidate the complex, multifactorial aetiology of late onset breast cancer. ..
  53. D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
    Eric Storch; Fiscal Year: 2007
    ..Such agents may have utility in improving outcome, reducing premature therapy termination, and targeting patients who have been treatment refractory. [unreadable] [unreadable] [unreadable]..
  54. Sensible Treatment of Obesity in Rural Youth- STORY
    David Janicke; Fiscal Year: 2006
    ..Findings will provide critical information for planning the R18 RCT. ..
  55. MAPPING SUSCEPTIBILITY ALLELES FOR BPH
    William Isaacs; Fiscal Year: 2001
    ....
  56. PUBLIC ATTITUDES TOWARDS DEATH AND ORGAN PROCUREMENT
    Laura Siminoff; Fiscal Year: 2001
    ..Finally, a community dialogue will be implemented to interpret and disseminate the findings and provide recommendations to policy makers. ..
  57. Aging, Acculturation, and Health: Korean American Elders
    Yuri Jang; Fiscal Year: 2005
    ..This study is an important step in expanding our understanding of the unique experiences of minority elders; further research will be developed based on the results from this pilot research. ..
  58. High Density Association Analysis of Lung Cancer
    Christopher I Amos; Fiscal Year: 2010
    ..We are collaborating with the International Lung Cancer Consortium so that it can further validate our findings for a variety of different populations, in future initiatives. ..
  59. METHYLPHENIDATE TREATMENT OF ADHD IN CHILDREN WITH TS
    Kenneth Gadow; Fiscal Year: 2004
    ..To evaluate the impact of tic severity and comorbid internalizing and externalizing symptoms on clinical outcome, children with ADHD/+tics will be compared with an additional sample of children with ADHD/-tics at ages 11 and 16 years. ..
  60. Infant hearing for modulated tones
    Barbara Cone Wesson; Fiscal Year: 2003
    ..This research will also result in methods for assessing threshold sensitivity and sound discrimination in infants that can be applied to those at risk for hearing loss or other auditory dysfunction. ..
  61. Resistant E.coli in Humans and Poultry
    James Johnson; Fiscal Year: 2005
    ..Does the research address a current and compelling problem of antimicrobial resistance that is of high public health importance and for which research is needed? [yes]. ..
  62. Genetic Epidemiology of Parkinson's Disease
    Karen Marder; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  63. Clinical Impact of Quinolone-Resistant E.coli carriage
    Ebbing Lautenbach; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  64. Neurobiologic Study of Psychological Distress & Dementia
    Robert S Wilson; Fiscal Year: 2010
    ....
  65. Nanoscale approaches to allelic silencing in myocardial disease states
    Euan Ashley; Fiscal Year: 2009
    ..This familial condition where the heart grows too thick is the most common cause of sudden death in young people and athletes. ..
  66. Markers of Risk for Nicotine Dependence in Youngsters
    Uma Rao; Fiscal Year: 2006
    ..Even if only a small subgroup of youngsters at risk for ND can be identified by such means, because of the many direct as well as indirect negative consequences associated with ND, this will be of great public health importance. ..