Genomes and Genes
point of care systems
Summary: Laboratory and other services provided to patients at the bedside. These include diagnostic and laboratory testing using automated information entry.
Articles from Journal RESEARCH
Articles from Journal RESEARCH1
Publications205 found, 100 shown here
- Reliability of point-of-care testing of INR in acute strokeTheresa L Green
Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Foothills Hospital, Rm C1101A, 1403 29th Street NW, Calgary, Alberta T2N 2T9, Canada
Can J Neurol Sci 35:348-51. 2008..The objective of this study was to evaluate the reliability, validity, and impact on clinical decision-making of a POCT device for INR testing in the setting of acute ischemic stroke (AIS)...
- Evaluation of a rapid bedside toxicology screen in patients suspected of drug toxicityChristian Tomaszewski
Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
J Emerg Med 28:389-94. 2005..Further testing will be required to verify the efficacy of the test in populations with a higher prevalence of phencyclidine and amphetamine abuse...
- Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing ScreenMichaela Trapl
Center of Clinical Neurosciences, Danube University, Krems, and the Department of Neurology, Landesklinikum Donauregion, Maria Gugging, Austria
Stroke 38:2948-52. 2007..The Gugging Swallowing Screen (GUSS) aims at reducing the risk of aspiration during the test to a minimum; it assesses the severity of aspiration risk and recommends a special diet accordingly...
- Excluding venous thromboembolism using point of care D-dimer tests in outpatients: a diagnostic meta-analysisG J Geersing
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
BMJ 339:b2990. 2009..To review the evidence on the diagnostic accuracy of the currently available point of care D-dimer tests for excluding venous thromboembolism...
- Point-of-care testing for patients with diabetes, hyperlipidaemia or coagulation disorders in the general practice setting: a systematic reviewAngela Gialamas
Discipline of General Practice, The University of Adelaide, Adelaide, South Australia
Fam Pract 27:17-24. 2010..Point-of-care testing (PoCT) is increasingly being used in the general practice setting and has the potential to provide improved health outcomes for patients...
- Finding and applying evidence during clinical rounds: the "evidence cart"D L Sackett
Nuffield Department of Clinical Medicine, University of Oxford, England
JAMA 280:1336-8. 1998..Physicians need easy access to evidence for clinical decisions while they care for patients but, to our knowledge, no investigators have assessed use of evidence during rounds with house staff...
- Ultrasound diagnosis of occult pneumothoraxDaniel A Lichtenstein
Medical Intensive Care Unit, Hopital Ambroise Pare, Boulogne Paris Ouest, France
Crit Care Med 33:1231-8. 2005..Pneumothorax can be missed by bedside radiography, and computed tomography is the current alternative. We asked whether lung ultrasound could be of any help in this situation...
- Does point-of-care testing lead to the same or better adherence to medication? A randomised controlled trial: the PoCT in General Practice TrialAngela Gialamas
Discipline of General Practice, University of Adelaide, Adelaide, SA, Australia
Med J Aust 191:487-91. 2009..To compare the clinical effectiveness of point-of-care testing (PoCT) with that of pathology laboratory testing, as measured by patients' adherence to medication...
- Evaluation of "point of care" devices in the measurement of low blood glucose in neonatal practiceH T Ho
Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China
Arch Dis Child Fetal Neonatal Ed 89:F356-9. 2004..Low blood glucose in newborns is difficult to detect clinically. Hence a reliable "point of care" device (glucometer) for early detection and treatment of low glucose is needed...
- Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devicesMichael T Ganter
Department of Anesthesia and Perioperative Care, University of CA San Francisco, San Francisco, California, USA
Anesth Analg 106:1366-75. 2008..To ensure optimal accuracy and performance, standardized procedures for blood sampling and handling, strict quality controls and trained personnel are required...
- Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST)A W Kirkpatrick
Department of Critical Care Medicine, Foothills Medical Centre, Calgary, Alberta, Canada
J Trauma 57:288-95. 2004..However, the diagnostic utility of hand-held US has not been previously evaluated in this role...
- Diagnostic accuracy of a bedside D-dimer assay and alveolar dead-space measurement for rapid exclusion of pulmonary embolism: a multicenter studyJ A Kline
Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28232 2816, USA
JAMA 285:761-8. 2001..A previous study suggested that the combination of a normal D-dimer assay and normal alveolar dead-space fraction is a highly sensitive screening test for pulmonary embolism (PE)...
- Bedside procalcitonin and C-reactive protein tests in children with fever without localizing signs of infection seen in a referral centerAnnick Galetto-Lacour
Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
Pediatrics 112:1054-60. 2003..To assess the value of bedside tests for predicting the occurrence of severe bacterial infections (SBIs) in children with fever without source...
- Bench to bedside: electrophysiologic and clinical principles of noninvasive hemodynamic monitoring using impedance cardiographyRichard L Summers
Department of Emergency Medicine, University of Mississippi Medical Center, Jackson 39216, USA
Acad Emerg Med 10:669-80. 2003....
- Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgeryRajendra H Mehta
Duke Clinical Research Institute, Durham, NC 27715, USA
Circulation 114:2208-16; quiz 2208. 2006..Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling...
- Safely ruling out deep venous thrombosis in primary careHarry R Buller
Academic Medical Center, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands
Ann Intern Med 150:229-35. 2009..Up to 90% of patients referred for ultrasonography with suspected deep venous thrombosis (DVT) of the leg do not have the disease...
- Effectiveness of point-of-care testing for therapeutic control of chronic conditions: results from the PoCT in General Practice TrialTanya K Bubner
Discipline of General Practice, University of Adelaide, Adelaide, SA
Med J Aust 190:624-6. 2009..To compare the clinical effectiveness of point-of-care testing (PoCT) and that of pathology laboratory testing, as measured by therapeutic control in chronic conditions...
- Quantitative assessment of pleural effusion in critically ill patients by means of ultrasonographyPhilippe Vignon
Medical Surgical Intensive Care Unit, Dupuytren Teaching Hospital, Limoges, France
Crit Care Med 33:1757-63. 2005..To assess the ability of ultrasonography to identify the presence and assess the volume of pleural effusion in the intensive care unit setting...
- Point of care testing in the emergency departmentGregory J Fermann
Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267, USA
J Emerg Med 22:393-404. 2002..Patient care issues must be weighed against the cost of implementing POC testing and supporting the infrastructure needed to maintain this technology in the ED...
- An evaluation of five bedside information products using a user-centered, task-oriented approachRose Campbell
Department of Medical Informatics and Clinical Epidemiology, School of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97239, USA
J Med Libr Assoc 94:435-41, e206-7. 2006..The paper compares several bedside information tools using user-centered, task-oriented measures to assist those making or supporting purchasing decisions...
- Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery. A multicenter studyPierre Toulon
CHU, hopital de Cimiez, Service d Hematologie Biologique, 4 avenue de la Reine Victoria, BP 1179, F 06003 Nice Cedex 1, France
Thromb Haemost 101:394-401. 2009..These results suggest that, in providing a rapid answer, POC-based monitoring of PT (in percentage) using the CoaguChek device could be validly used in patients undergoing haemorrhagic surgical procedures...
- Answering questions at the point of care: do residents practice EBM or manage information sources?Gary McCord
Department of Family Medicine, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio, USA
Acad Med 82:298-303. 2007....
- Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgeryL Shore-Lesserson
Department of Anesthesiology, Mount Sinai Medical Center, New York, New York 10029, USA
Anesth Analg 88:312-9. 1999..These data support the use of TEG in an algorithm to guide transfusion therapy in complex cardiac surgery...
- Near-patient testing of potassium levels using arterial blood gas analysers: can we trust these results?R J P José
Department of Intensive Care Medicine, Broomfield Hospital, Court Road, Broomfield CM1 7ET, UK
Emerg Med J 25:510-3. 2008..At times there is uncertainty whether clinical decisions can be based on the potassium result obtained from arterial blood gas (ABG) analysers or if laboratory values should be awaited...
- Impact of surgeon-performed ultrasound on diagnosis of abdominal painA Lindelius
Karolinska Institutet, Department of Clinical Science and Education, Sodersjukhuset, Stockholm, Sweden
Emerg Med J 25:486-91. 2008..A randomised study was performed to evaluate the diagnostic accuracy of surgeon-performed ultrasound in the emergency department for patients presenting with abdominal pain...
- Focused ultrasound training for cliniciansSuzanne Le P Langlois
Department of Medical Imaging, The Townsville Hospital, Douglas, Queensland, Australia
Crit Care Med 35:S138-43. 2007..Training and supervision in rural, remote, and austere environments provides added challenges...
- Goal-directed abdominal ultrasonography: impact on real-time decision making in the emergency departmentDavid Bassler
Department of Emergency Medicine, Alameda County Medical Center, Highland Hospital, Oakland, California 94602, USA
J Emerg Med 24:375-8. 2003..Bedside ultrasonography in the ED has an important impact on real-time decision-making, particularly in terms of the certainty of diagnosis...
- Improving management of patients with acute cough by C-reactive protein point of care testing and communication training (IMPAC3T): study protocol of a cluster randomised controlled trialJochen W L Cals
Maastricht University, Care and Public Health Research Institute, Department of General Practice, Maastricht, The Netherlands
BMC Fam Pract 8:15. 2007..The aim of this paper is to describe the design and methods of a study to assess two interventions for improving LRTI management in general practice...
- Lung ultrasound in acute respiratory distress syndrome and acute lung injuryCharlotte Arbelot
Surgical Intensive Care Unit, Department of Anesthesiology and Critical Care, Assistance Publique Hopitaux de Paris, University of Paris 6 Pierre et Marie Curie, Paris, France
Curr Opin Crit Care 14:70-4. 2008..Lung ultrasound at the bedside can provide accurate information on lung status in critically ill patients with acute respiratory distress syndrome...
- Improved infrared spectrophotometer for point-of-care patient 13C-urea breath testing in the primary care settingAntone R Opekun
Baylor College of Medicine, Department of Medicine, Family and Community Medicine, 6550 Fannin Street SM 1122, Houston, TX 77030 2399, USA
Clin Biochem 38:731-4. 2005..The 13C-urea breath test provides non-invasive testing for Helicobacter pylori infection with the possibility of analysis at the point of care. Point of care tests require accurate and efficient desktop instrumentation...
- Performance evaluation of a new compact hematology analyzer, the Sysmex pocH-100iC Briggs
Department of Haematology, University College London Hospital, London, United Kingdom
Lab Hematol 9:225-33. 2003..Results for neutrophils (r2 = 0.996), lymphocytes (r2 = 0.999), and the "mixed" population of cells (r2 = 0.611) indicated the pocH-100i analyzer would be highly suitable for low-volume laboratories and near-patient services...
- Prospective study of the diagnostic accuracy of the simplify D-dimer assay for pulmonary embolism in emergency department patientsJeffrey A Kline
Director, Emergency Medicine Research, Department of Emergency Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28323 2861, USA
Chest 129:1417-23. 2006....
- Is perioperative point-of-care prothrombin time testing accurate compared to the standard laboratory test?Natalie Urwyler
University Department of Anesthesiology and Pain Therapy, University Hospital of Bern, Bern, Switzerland
Thromb Haemost 102:779-86. 2009..These findings suggest that PoC testing will be useful for monitoring intraoperative prothrombin time when coagulopathy is suspected. It could lead to a more rational use of expensive and limited blood bank resources...
- Quality assessment of CoaguChek point-of-care prothrombin time monitors: comparison of the European community-approved procedure and conventional external quality assessmentLeon Poller
Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
Clin Chem 52:1843-7. 2006....
- Bedside diagnostic laparoscopy in the intensive care unit: a 13-year experienceEduardo J Jaramillo
Texas Endosurgery Institute, San Antonio, Texas 78222, USA
JSLS 10:155-9. 2006..One option in the diagnosis of these difficult patients is bedside laparoscopy, as it avoids patient transport, is very accurate, and maintains ICU monitoring...
- Performance evaluation of the CoaguChek S systemWinfried Plesch
Haematologica 87:557-9. 2002
- Clinical experiences with a new semi-quantitative solid phase immunoassay for rapid measurement of procalcitoninM Meisner
Department of Anaesthesiology and Intensive Care Medicine, Friedrich Schiller Universitat Jena, Germany
Clin Chem Lab Med 38:989-95. 2000..However, for the follow-up of PCT concentrations and routine daily measurements, the quantitative luminometric assay should be preferred, when available...
- Usefulness of a hand-held ultrasound device for bedside examination of left ventricular functionBruce J Kimura
Department of Cardiology, Scripps Mercy Medical Center, San Diego, California, USA
Am J Cardiol 90:1038-9. 2002
- Pilot study of a point-of-use decision support tool for cancer clinical trials eligibilityP P Breitfeld
Regenstrief Institute, Indiana University School of Medicine, Indianapolis 46202 2859, USA
J Am Med Inform Assoc 6:466-77. 1999..This decision support tool and the decision framework on which it is based could be used for multiple trials and different cancer sites...
- Accuracy and feasibility of point-of-care and continuous blood glucose analysis in critically ill ICU patientsAnouk M Corstjens
Department of Anesthesiology, University Medical Center Groningen, Groningen, The Netherlands
Crit Care 10:R135. 2006..The study was performed as a single-centre, prospective, observational study in a 12-bed medical ICU of a university hospital...
- Field evaluation of the performance and testing costs of a rapid point-of-care test for syphilis in a red-light district of Manaus, BrazilA S Benzaken
Fundação Alfredo da Matta, Manaus, Brazil
Sex Transm Infect 84:297-302. 2008..To assess the performance, usefulness and cost of a rapid treponemal antibody assay (VisiTect Syphilis) to detect syphilis in high risk populations...
- Prospective, multi-centre clinic-based evaluation of four rapid diagnostic tests for syphilisD Mabey
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 82:v13-6. 2006..To evaluate prospectively four rapid, point-of-care serological tests for syphilis in prenatal or high risk populations in four countries...
- The status of bedside ultrasonography training in emergency medicine residency programsFrancis L Counselman
Department of Emergency Medicine, Eastern Virginia Medical School, Norfolk 23507, USA
Acad Emerg Med 10:37-42. 2003..Program training content is currently driven by the recently published "Model of the Clinical Practice of Emergency Medicine," which includes BU as a necessary skill...
- Do clinicians use online evidence to support patient care? A study of 55,000 cliniciansJohanna I Westbrook
Centre for Health Informatics, Level 2, Samuels Building, University of New South Wales, Kensington, 2052, Australia
J Am Med Inform Assoc 11:113-20. 2004....
- Design and implementation of GRIP: a computerized glucose control system at a surgical intensive care unitMathijs Vogelzang
Department of Surgery, Medical Center Groningen, University of Groningen, Groningen, The Netherlands
BMC Med Inform Decis Mak 5:38. 2005..Current nurse-driven protocols are paper-based and, therefore, rely on simple rules. For safety and efficiency a computer decision support system that employs complex logic may be superior to paper protocols...
- Pre-hospital detection of acute myocardial infarction with ultra-rapid human fatty acid-binding protein (H-FABP) immunoassayPatrick Ecollan
SAMU, Pitie Salpetriere University Hospital, Paris, France
Int J Cardiol 119:349-54. 2007..To evaluate the diagnostic performance of a portable semi-quantitative whole blood immunoassay measuring soluble human fatty acid-binding protein [H-FABP] (CardioDetect) for the pre-hospital detection of myocardial infarction (MI)...
- Clinical evaluation of point-of-care-testing of heart-type fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardial infarctionTakao Tanaka
Osaka Medical College, Takatsuki, Osaka, Japan
J Immunoassay Immunochem 27:225-38. 2006..3%, while it was 100% with cardiac troponin T. The POCT of H-FABP is thought to be practical for the detection of cardiac damage and effective for the diagnosis of AMI in superacute phase within 3 hours and/or 6 hours...
- Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitusKamlesh Khunti
Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW
Br J Gen Pract 56:511-7. 2006..Tight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control...
- Malaria rapid diagnostic tests in tropical climates: the need for a cool chainPernille Jorgensen
World Health Organization Regional Office for the Western Pacific, Manila, The Philippines
Am J Trop Med Hyg 74:750-4. 2006..These results emphasize the need for good logistical planning during the introduction of point-of-care tests in tropical countries and the importance of considering the stability of diagnostic tests during procurement...
- Validation of an insulin infusion nomogram for intensive glucose control in critically ill patientsClarence Chant
Perioperative and Critical Care Services, Department of Pharmacy, St Michael s Hospital, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Pharmacotherapy 25:352-9. 2005..To evaluate the effectiveness, safety, and associated patient outcomes of a simplified, nurse-directed insulin nomogram designed to achieve intensive blood glucose level control (target range 90-144 mg/dl)...
- Physician-performed point-of-care echocardiography using a laptop platform compared with physical examination in the cardiovascular patientK T Spencer
Department of Cardiology, University of Chicago, Illinois 60637, USA
J Am Coll Cardiol 37:2013-8. 2001..The purpose of this study was to compare the results of physical examinations (PEs) performed by board-certified cardiologists with the results of point-of-care (POC) echocardiography in a group of patients with cardiovascular disease...
- Chest ultrasound for "Dummies"Peter Doelken
Chest 123:332-3. 2003
- Comparison of the Simplify D-dimer assay performed at the bedside with a laboratory-based quantitative D-dimer assay for the diagnosis of pulmonary embolism in a low prevalence emergency department populationM S Runyon
Department of Emergency Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, North Carolina 28323 2861, USA
Emerg Med J 25:70-5. 2008..The immunofiltration D-dimer assay could allow point-of-care testing for pulmonary embolism (PE). A study was undertaken to compare a clinician-performed qualitative D-dimer assay with the automated quantitative D-dimer test...
- Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patientsJoseph V Agostini
Clinical Epidemiology Research Center, VA Connecticut Healthcare Center, West Haven, CT 06516, USA
J Am Geriatr Soc 55:43-8. 2007..To develop a feasible, inexpensive, point-of-care computerized reminder to improve sedative-hypnotic prescribing in hospitalized older people...
- Testing for sexually transmitted infections: a brave new world?R W Peeling
Sex Transm Infect 82:425-30. 2006
- Comparison of structured use of routine laboratory tests or near-patient assessment with clinical judgement in the management of bleeding after cardiac surgeryM S Avidan
Department of Anesthesiology, Washington University School of Medicine, St Louis, MO 63110, USA
Br J Anaesth 92:178-86. 2004....
- Rapid assessment of cardiac anatomy and function with a new hand-carried ultrasound device (OptiGo): a comparison with standard echocardiographyM Rugolotto
Division of Cardiovascular Medicine, Stanford University Medical Center, Stanford, California 94305-5233, USA
Eur J Echocardiogr 2:262-9. 2001....
- [Bedside thrombelastography. Cost reduction in cardiac surgery]G J Spalding
Herzchirurgie, Herzzentrum Brandenburg, Ladeburger Strasse 17, 16321 Bernau bei Berlin
Anaesthesist 56:765-71. 2007..We analyzed the bedside coagulation test (ROTEM) in order to verify clot forming quality and to find a cost-effective treatment algorithm...
- Oxygen effects on glucose meter measurements with glucose dehydrogenase- and oxidase-based test strips for point-of-care testingZ Tang
Point-of-Care Testing Center for Teaching and Research, University of California, Davis, CA, USA
Crit Care Med 29:1062-70. 2001....
- Using wireless handheld computers to seek information at the point of care: an evaluation by cliniciansSusan E Hauser
Lister Hill National Center for Biomedical Communications, National Library of Information, 8600 Rockville Pike, Bethesda, MD 20894, USA
J Am Med Inform Assoc 14:807-15. 2007..To evaluate: (1) the effectiveness of wireless handheld computers for online information retrieval in clinical settings; (2) the role of MEDLINE in answering clinical questions raised at the point of care...
- Clinical team functioning and IT innovation: a study of the diffusion of a point-of-care online evidence systemA Sophie Gosling
Centre for Health Informatics, Faculty of Medicine, University of New South Wales, Sydney, Australia
J Am Med Inform Assoc 10:244-51. 2003..To examine the relationships between clinical team characteristics and the adoption of the online evidence system...
- Innovations in technology for critical care medicineMartin Chapman
University of Toronto, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Crit Care 8:74-6. 2004..The monitoring section discusses recent claims of improved efficiency with telemedicine for intensive care units...
- Accurate and precise isotope dilution mass spectrometry method for determining glucose in whole bloodU Hannestad
Department of Clinical Chemistry, University Hospital, Linkoping, Sweden
Clin Chem 43:794-800. 1997..For all samples the HemoCue analyzer results had a mean bias of +2.0% compared with the ID GC-MS results...
- Bedside functional imaging of the premature infant brain during passive motor activationS R Hintz
Biomedical Optics Group, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Hansen Physics Laboratory, Palo Alto, California, USA
J Perinat Med 29:335-43. 2001..Imaging methods, which use near-infrared light allow for non-invasive measurements by taking advantage of the fact that hemoglobin is a strong absorber at these wavelengths...
- Pilot study of the accuracy of bedside glucometry in the intensive care unitJ G Ray
Division of Critical Care, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Crit Care Med 29:2205-7. 2001....
- Utility and diagnostic accuracy of hand-carried ultrasound for emergency room evaluation of chest painShaul Atar
Department of Cardiology, Ha Emek Medical Center, Afula, Israel
Am J Cardiol 94:408-9. 2004....
- How useful is hand-carried bedside echocardiography in critically ill patients?G M Goodkin
Noninvasive Cardiology Laboratory, New York University School of Medicine, New York 10016, USA
J Am Coll Cardiol 37:2019-22. 2001..The study compared a hand-carried echocardiography (HC) device with standard echocardiography (SE) in critically ill patients...
- Neurointensive care unit system for continuous electrophysiological monitoring with remote web-based reviewAndre J W van der Kouwe
Cleveland Clinic Foundation, Cleveland, OH 44195, USA
IEEE Trans Inf Technol Biomed 7:130-40. 2003..We demonstrate its application in a few diverse neurological intensive care cases and a case in the interventional neuroradiology suite...
- Reliability of point-of-care hematocrit, blood gas, electrolyte, lactate and glucose measurement during cardiopulmonary bypassJ Steinfelder-Visscher
Department of Extra Corporeal Circulation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Perfusion 21:33-7. 2006..In this prospective clinical study, the analytical performance of the GEM Premier 3000 was compared with the Ciba Corning 865 analyser for blood gas/electrolytes/metabolites, and for hematocrit with the Sysmex XE 2100 instrument...
- Seroprotection against tetanus in patients attending an emergency department in Belgium and evaluation of a bedside immunotestMuriel Stubbe
Department of Emergency Medicine, Erasme University Hospital, Brussels, Belgium
Eur J Emerg Med 14:14-24. 2007..In most emergency departments, tetanus prophylaxis currently relies on vaccination history. Bedside evaluation of tetanus immunity may improve this process...
- The Massey Bedside Swallowing ScreenRegina Massey
Mount Carmel College of Nursing, Epilepsy Center Mount Carmel West Neurology Center of Columbus, USA
J Neurosci Nurs 34:252-3, 257-60. 2002..Sensitivity and specificity were calculated as 100%. The chi-square test showed that use of the Massey Bedside Swallowing Screen might provide nurses with a useful tool for assessing swallowing function of patients with a stroke...
- Are the Duke criteria really useful for the early bedside diagnosis of infective endocarditis? Results of a prospective multicenter trialEnrico Cecchi
Cardiology Department, Maria Vittoria Hospital, Turin, Italy
Ital Heart J 6:41-8. 2005....
- Accuracy of the CoaguChek XS for point-of-care international normalized ratio (INR) measurement in children requiring warfarinMary E Bauman
Stollery Children s Hospital, University of Alberta, Edmonton, AB, Canada
Thromb Haemost 99:1097-103. 2008..11 (-0.20; 0.42) and 0.13 (-0.22; 0.48) at the two time points, respectively. In conclusion, the CoaguChek XS meter appraisal generates an accurate and precise INR measure in children when compared to laboratory INR test results...
- The quick-read C-reactive protein test for the prediction of bacterial gastroenteritis in the pediatric emergency departmentNufar Marcus
Unit of Emergency Medicine, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
Pediatr Emerg Care 23:634-7. 2007..To determine the clinical usefulness of the bedside Quick-Read (QR) C-reactive protein (CRP) test for predicting bacterial gastroenteritis in the pediatric emergency department...
- Triage patients with suspected pulmonary embolism in the emergency department using a portable ultrasound deviceNicolas Mansencal
Department of Cardiology, University Hospital Ambroise Pare, Assistance Publique Hopitaux de Paris, UFR de médecine Paris Île de France Ouest, Faculté de Versailles Saint Quentin en Yvelines, Boulogne, France
Echocardiography 25:451-6. 2008....
- Accuracy of bedside glucometry in critically ill patients: influence of clinical characteristics and perfusion indexArnaud Desachy
Medical Surgical Intensive Care Unit, Centre Hospitalier General, Angouleme, France
Mayo Clin Proc 83:400-5. 2008..To determine the accuracy of bedside glucose strip assay on capillary blood and on whole blood and to identify factors predictive of discrepancies with the laboratory method...
- Anticoagulation monitoring part 1: warfarin and parenteral direct thrombin inhibitorsSarah A Spinler
Cardiovascular Division, Department of Medicine, Philadelphia College of Pharmacy, University of Pennsylvania, Philadelphia, PA 19104 4495, USA
Ann Pharmacother 39:1049-55. 2005..To review the availability, mechanisms, limitations, and clinical application of point-of-care (POC) devices used in the management of warfarin and parenteral direct thrombin inhibitors...
- Comparison of ACT point-of-care measurements: repeatability and agreementY P J Bosch
Department of Extra Corporeal Circulation, University Hospital Maastricht, Maastricht, The Netherlands
Perfusion 21:27-31. 2006....
- A novel method for insertion of post-pyloric feeding tubes at the bedside without endoscopic or fluoroscopic assistance: a prospective studyCornelis Slagt
Department of Anaesthesiology, General Hospital De Heel, Zaans Medical Center, P O Box 210, 1500 EE Zaandam, The Netherlands
Intensive Care Med 30:103-7. 2004..To assess a novel method, adapted from already published literature, for bedside placement of nasojejunal feeding tubes using erythromycin, air insufflation of the stomach and continuous ECG guidance...
- Use of dynamic compliance for open lung positive end-expiratory pressure titration in an experimental studyFernando Suarez-Sipmann
Intensive Care Unit, Fundacion Jimenez Diaz Capio, Avenida de los Reyes Catolicos 2, 28010 Madrid, Spain
Crit Care Med 35:214-21. 2007..We tested whether the continuous monitoring of dynamic compliance could become a useful bedside tool for detecting the beginning of collapse of a fully recruited lung...
- European Concerted Action on Anticoagulation (ECAA): multicentre international sensitivity index calibration of two types of point-of-care prothrombin time monitor systemsL Poller
ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
Br J Haematol 116:844-50. 2002..In these circumstances, the modified WHO-type ISI calibration appeared to be satisfactory for the POCT whole-blood monitors...
- How accurate are currently used methods of determining glycemia in critically ill patients, and do they affect their clinical course?G Chrousos
Crit Care Med 33:2849-51. 2005
- Point-of-care test identifies diabetic ketoacidosis at triageRosanne Naunheim
Department of Emergency Medicine, Washington University, St Louis, MO, USA
Acad Emerg Med 13:683-5. 2006....
- Precision and accuracy of the bedside examination in detecting an ejection fraction of less than 40% following acute myocardial infarctionD Massel
Department of Medicine, University of Western Ontario, London, Ontario
Can J Cardiol 20:411-6. 2004..Left ventricular function is the most important determinant of prognosis following myocardial infarction...
- Bedside tests of B-type natriuretic peptide in the diagnosis of left ventricular diastolic dysfunction in hypertensive patientsTiemin Wei
Department of Cardiology, Lishui City Central Hospital, Zhejiang Province, PR China
Eur J Heart Fail 7:75-9. 2005..To investigate the value of B-type natriuretic peptide (BNP) in diagnosing left ventricular diastolic dysfunction in patients with hypertension...
- Measuring statistical agreement between four point of care (POC) lactate meters and a laboratory blood analyzer in catsMark J Acierno
Department of Veterinary Clinical Science, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70810, USA
J Feline Med Surg 10:110-4. 2008..Other commercially available POC meters produced acceptable agreement...
- Handheld, portable ultrasound in the neonatal intensive care nursery: a new, inexpensive tool for the rapid diagnosis of common neonatal problemsVladimir Burdjalov
Department of Pediatrics, Division of Neonatology, SUNY Stony Brook, Stony Brook, NY 11794 8111, USA
J Perinatol 22:478-83. 2002..This paper illustrates some of the capabilities of this simplified device, and the value of having continuous on-site ultrasound availability in the NICU...
- [Pruritometer 1: Portable measuring system for quantifying scratching as an objective measure of cholestatic pruritus]H Stein
Biomed Tech (Berl) 41:248-52. 1996..Pruritometer 2, which will enable scratch frequency and intensity distribution over time to be determined, is presently being developed...
- Minimum numbers of fresh whole blood and plasma samples from patients and healthy subjects for ISI calibration of CoaguChek and RapidPointCoag monitorsLeon Poller
European Concerted Action on Anticoagulation, Central Facility, School of Biological Sciences, University of Manchester, England
Am J Clin Pathol 117:892-9. 2002....
- Goal-directed ultrasound in the detection of long-bone fracturesThomas H Marshburn
Medical Operations, Office of Space Medicine, NASA Johnson Space Center, Houston, Texas 77058, USA
J Trauma 57:329-32. 2004..New portable ultrasound (US) systems are capable of detecting fractures in the remote setting. However, the accuracy of ultrasound by physicians with minimal ultrasound training is unknown...
- Point of care blood ketone testing of diabetic patients in the emergency departmentFirat Bektas
Department of Emergency Medicine, School of Medicine, University of Akdeniz, Antalya, Turkey
Endocr Res 30:395-402. 2004..This device can be used as a reliable diagnostic test to detect emergency metabolic problems in diabetic patients, such as diabetic ketosis or ketoacidosis...
- Real-time B-mode ultrasound in the ED saves time in the diagnosis of deep vein thrombosis (DVT)Daniel Theodoro
Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York, USA
Am J Emerg Med 22:197-200. 2004..0001). EPs and ISs had excellent agreement (kappa = 0.9). Compression ultrasound performed by EPs resulted in a significant decreased time to disposition. Agreement with ISs was excellent...
- Accuracy of capillary whole blood international normalized ratio on the CoaguChek S, CoaguChek XS, and i-STAT 1 point-of-care analyzersBrad S Karon
Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Clin Pathol 130:88-92. 2008..5 INR units from the reference method. Median bias between CoaguChek S capillary whole blood and laboratory plasma INRs changed over time, demonstrating the need for ongoing quality assurance measures for POC INR programs...
- ABSCESS: applied bedside sonography for convenient evaluation of superficial soft tissue infectionsBenjamin T Squire
Department of Emergency Medicine, University of California, Irvine, Orange, CA 92868, USA
Acad Emerg Med 12:601-6. 2005..Soft tissue infections are a common presenting complaint in the emergency department (ED). The authors sought to determine the utility of ED bedside ultrasonography (US) in detecting subcutaneous abscesses...
- Bedside diagnosis of coronary artery disease: a systematic reviewAndrea Akita Chun
Department of General Internal Medicine, University of Washington, Harborview Medical Center, Seattle 98104 2499, USA
Am J Med 117:334-43. 2004..To assess the accuracy of bedside findings for diagnosing coronary artery disease and acute myocardial infarction...
- Community screening for left ventricular hypertrophy in patients with hypertension using hand-held echocardiographyRoxy Senior
Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Rd, Harrow, Middlesex, HAI 3UJ United Kingdom
J Am Soc Echocardiogr 17:56-61. 2004..Thus, hand-held echocardiography devices accurately assessed LVH and may be used for community-based screening for LVH in targeted patients with hypertension...
- Point-of-care urinary pneumococcal antigen test in the emergency department for community acquired pneumoniaC Weatherall
Department of Microbiology and Infectious Diseases, Concord Repatriation General Hospital, Sydney, Australia
Emerg Med J 25:144-8. 2008..A study was undertaken to assess whether PNAG testing can be reliably performed and interpreted by staff in an adult emergency department and whether rapid results influence initial treatment decisions...
- Evaluation of Binax NOW RSV as an acute point-of-care screening test in a paediatric accident and emergency unitP L Mackie
Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN
Commun Dis Public Health 7:328-30. 2004..The simplicity of Binax NOW RSV should not detract from training staff and maintaining consistent vigilance on quality control...
- Focused assessment with sonography for trauma patients by clinicians: Initial experience and resultsJohn Vassiliadis
Department of Emergency Medicine, Division of Surgery, Westmead Hospital, Westmead, New South Wales, Australia
Emerg Med (Fremantle) 15:42-8. 2003..To describe the establishment of a service to provide bedside focused assessment sonography in trauma and to evaluate the service to date...
- B-type natriuretic peptide rapid assay: a diagnostic test for heart failureIrma B Ancheta
University of Phoenix, Jacksonville, FL 32218, USA
Dimens Crit Care Nurs 25:149-54; quiz 155-6. 2006..This article focuses on the description of the diagnostic performance of the BNP rapid assay, its clinical dimensions, and its implications to nursing practice and collaborative practice models...
- Diagnostic accuracy of the Triage D-dimer test for exclusion of venous thromboembolism in outpatientsTimothy Ghys
Department of Hematology, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, B 1090 Brussels, Belgium
Thromb Res 121:735-41. 2008..We evaluated the diagnostic performance of the Triage D-dimer test, a new fast quantitative point-of-care whole blood D-dimer assay and compared it with the Vidas D-dimer assay...
- Technology to Improve Medication Safety in Nursing HomesJill Scott Cawiezell; Fiscal Year: 2004....
- LOW-COST, GEIGER-MODE MUAPD ARRAYS FOR CYTOMETRYARIEH KARGER; Fiscal Year: 2001....
- Electric-Field Assisted Isothermal On-Chip Amplification of DNADalibor Hodko; Fiscal Year: 2006..Potential applications are envisioned in portable and/or point of care systems for detection of pathogens, infectious diseases and/or biological agents and emerging pathogens...
- Cardiac Troponin Testing for Myocardial InfarctionFred Apple; Fiscal Year: 2001..abstract_text> ..
- Expired CO2/O2 Analysis to Diagnose Pulmonary EmbolismJEFFREY KLINE; Fiscal Year: 2008..This project will fund a clinical study designed to test the diagnostic accuracy of a hand- held breath device that detects the altered gas exchange physiology caused by PE in post-surgical and other patients at high risk for PE. ..
- Physician Training Program in Neonatal BiologyJohn Widness; Fiscal Year: 2007..With NIH support beyond that which the investigators currently enjoy, the investigators will be able to significantly enhance the research training experiences they offer their postdoctoral physician trainees in neonatal medicine. ..
- Surrogate markers for Severe Pulmonary EmbolismJEFFREY KLINE; Fiscal Year: 2005..This study will determine if criteria that are widely and immediately available in most hospitals can be used to risk-stratify severity of PE and to clarify the role of nonmalignant thrombophilias on the prognosis of PE. ..
- Pretest Probability Assessment for Pulmonary EmbolismJEFFREY KLINE; Fiscal Year: 2005..In phase III, we will test the validity of the PE PREtest Consult TM and determine if the use of the PE PREtest ConsultTM will decrease unnecessary testing for PE. ..
- Parent Initiated Prevention ProgramDimitri Christakis; Fiscal Year: 2005..3) To improve parental perceptions of the quality of care provided.H3: Compared to controls, PIPP parents will report higher scores on selected Consumer Assessment of Health Plans (CAHPS) items. ..
- p12CDK2-AP1 in Cell Cycle Control & Oral CarcinogenesisDavid Wong; Fiscal Year: 2006..abstract_text> ..
- Insular AD Pathology and Autonomic FunctionDonald Royall; Fiscal Year: 2006..unreadable] [unreadable]..
- Usability Testing of a CDSS for Tobacco Use TreatmentTHEODORE MARCY; Fiscal Year: 2005..The effectiveness of the developed through this process would be assessed in a subsequent research proposal using a randomized controlled trial design. ..
- Oral-Based DiagnosticsDaniel Malamud; Fiscal Year: 2006..This conference will focus on advances and new technologies in the oral diagnostics field and their utility for detection of health status. [unreadable] [unreadable] [unreadable]..
- Creighton Health Services Research Development ProjectKimberly Galt; Fiscal Year: 2007..Funding of this BRIC will facilitate the capacity needed to advance the Creighton University's health services research mission in a more rapid and sustainable fashion. [unreadable] [unreadable] [unreadable] [unreadable]..
- CPP Management Information Feedback and NursingCatherine Kirkness; Fiscal Year: 2007..abstract_text> ..
- NIH Task Force on Childhood Motor DisordersTerence Sanger; Fiscal Year: 2006..The ultimate objective is to improve the functional abilities and societal participation of children with motor disorders. ..
- Palliative Oxygen for the Relief of BreathlessnessAmy Abernethy; Fiscal Year: 2007..The results will also advance a long-standing international debate about the role of palliative oxygen for intractable dyspnea and it's funding. [unreadable] [unreadable] [unreadable]..
- Salivary Proteomic & Genomic Biomarkers for Primary Sjogren's SyndromeDavid T Wong; Fiscal Year: 2010....
- Towards Mega-Throughput, Label-free Genomics and Proteomics: Revolutionizing MicrAydogan Ozcan; Fiscal Year: 2009....
- Computer Decision Aid for ADHD Management (CDAAM)Aaron E Carroll; Fiscal Year: 2010..We will assess the quality of ADHD services at baseline and again at 12 months post implementation. These methods will allow a thorough description of the intervention's role in the process of ADHD management. ..
- Improving Heart Failure Risk Stratification in the EDAlan B Storrow; Fiscal Year: 2010..In collaboration with outcomes and effectiveness researchers, we plan to conduct further studies to test the efficacy of our risk model. ..
- IMPROVING THE DETECTION LIMIT OF POTENTIOMETRIC SENSORSJoseph Wang; Fiscal Year: 2008..The perturbance of such fluxes by surface binding events will be used to explore novel approaches to biosensing at liquid-polymer interfaces. ..
- Medication Reconciliation: A Team ApproachJeffrey Greenwald; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Mobile Tool for Adolescent Diabetes ManagementAaron Carroll; Fiscal Year: 2008..This research request will form the foundation of an R01 proposal to rigorously study the tool's impact on adolescent diabetes management ..
- Gastric Tube Placement in Young ChildrenMarsha Ellett; Fiscal Year: 2008..Results from this study will increase the safety of using gastric tubes in young children. ..
- Reducing Harm to Patients from Diagnostic ErrorsETA BERNER; Fiscal Year: 2007..To leverage AHRQ funding, additional support will be provided by registration fees, vendors, non-profit organizations and in-kind logistic support from the Society for Medical Decision Making. [unreadable] [unreadable] [unreadable]..
- Creation and demonstration of a palliative care research cooperative groupJean S Kutner; Fiscal Year: 2010....
- VAS-COG 2007Donald Royall; Fiscal Year: 2007..Many vascular cognitive disorders are preventable and potentially reversible. VAS-COG will provide a forum in which information on these important conditions can be exchanged and disseminated. [unreadable] [unreadable] [unreadable]..
- Physician Adherence to Tobacco Use Treatment GuidelinesTHEODORE MARCY; Fiscal Year: 2005..The candidate's work will be under the sponsorship of Dr. Brian Flynn of the Office of Health Promotion Research at the University of Vermont. ..
- Anti-HIV Activity of Lung SRCR (gp-340) in SalivaDaniel Malamud; Fiscal Year: 2005..abstract_text> ..
- PHARMACOLOGY OF COMBINED EPHEDRINE/CAFFEINE SUPPLEMENTSChristine Haller; Fiscal Year: 2004..The long-term objective for the proposed studies is to develop Dr. Haller into an independent career clinical researcher in this field of study. ..
- A Microfluidic Diffusion ImmunoassayPaul Yager; Fiscal Year: 2004..abstract_text> ..
- MICROASSAYS FOR ENZYME ACTIVITYWilson Smart; Fiscal Year: 2004..abstract_text> ..
- Childhood Motor Impairment and Assisted CommunicationTerence Sanger; Fiscal Year: 2004....
- Research Infrastructure Improvement for The UCLA SODDavid Wong; Fiscal Year: 2003..abstract_text> ..
- Online MRI Positioning and Real-Time Motion CorrectionAndre van der Kouwe; Fiscal Year: 2004..The technology will be evaluated in a group of healthy volunteers. ..
- UCLA Collaborative Oral Fluid Diagnostic Research CenterDavid Wong; Fiscal Year: 2005..The translational applications and opportunities are enormous. Significant institutional commitments and corporate sponsorships are in place, fulfilling the research, training, as well as technology transfer missions of NIDCR. ..
- MECHANISMS OF HORMONE THERAPY IN POSTMENOPAUSAL WOMENL Newby; Fiscal Year: 2003....
- A Microfluidic Diffusion ImmunoassayPaul Yager; Fiscal Year: 2002..abstract_text> ..
- IMMUNOPROBES FOR LUBRICIN FROM HUMAN SYNOVIAL FLUIDGregory Jay; Fiscal Year: 2003..This principal goal of this investigation is to develop new immunological probes and with these identify the concentration of lubricin in synovial fluid extracted from healthy and arthritic human joints. ..
- Arm Kinematics in Hyperkinetic Cerebral PalsyTerence Sanger; Fiscal Year: 2005..Hlatky will guide the design and implementation of clinical trials and outcome measure validation. The proposal includes coursework in cellular and molecular neurobiology and in the design of clinical research studies. ..
- Point Detection of Pathogens in Oral Samples via UPTDaniel Malamud; Fiscal Year: 2005..We now present a plan to combine these separate analyses into a single system that can be used on-site to analyze up to 200 target analytes. ..
- SUBMANDIBULAR SALIVARY PROTEINS SPECIFICALLY INHIBIT HIVDaniel Malamud; Fiscal Year: 2001..3. To determine the mechanism by which salivary proteins inhibit HIV infectivity using in vitro models of oral infection. 4. To define the significance of anti-HIV proteins in saliva obtained from HIV-seropositive donors. ..
- Aptamer Chips for Clinical Monitoring of Target ProteinsWilson Smart; Fiscal Year: 2002....
- Liability Markers for Deficit Schizophrenia?L Hong; Fiscal Year: 2004..We plan to use the preliminary data collected from this grant support to guide our full-scale search for phenotypic markers specifically associated with the liability for deficit schizophrenia and subsequent molecular genetic studies. ..
- Identifying molecular path of behavioural phenotype in schizophreniaL Hong; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Genomics and Proteomics of Oral Precancer ProgressionDavid Wong; Fiscal Year: 2009..The outcome of the validated molecular determinants will be utilized for biological mechanistic studies as well as translational research applications, directions that are well in place in our laboratories. ..
- Internet Based Patient-Centered Asthma Management SystemDimitri Christakis; Fiscal Year: 2009..Children in AsthmaNet families will be more likely to report using written care plans. Aim 4: to decrease the number of symptom days for children with asthma H4. Children in AsthmaNet families will experience fewer symptom days. ..
- Dyspraxia and Autonomic Control in Very Early ADDonald Royall; Fiscal Year: 2004..Some dementia treatments are known to reduce HRV, and possibly mortality as well. Alternatively, some psychotropics may increase arrhythmia-related mortality, possibly via a central mechanism. ..
- Expression Profiling in Canine Models of Human DiseaseGordon Tomaselli; Fiscal Year: 2005..As expression profile data is generated, it will be incorporated into a web-based database of canine gene expression profiles. ..
- Chronic Kidney Disease Morbidity, Mortality & PredictorsStephen Derose; Fiscal Year: 2005..Researchers may use this information to generate hypotheses and plan studies that include subjects with CKD. ..
- Breast Cancer Multi-dimensional Diffuse Optical ImagingBruce Tromberg; Fiscal Year: 2007..g. hormone replacement therapy (HRT) and neoadjuvant chemotherapy). ..
- Nanoliter Lab-on-a-chip for Protein CrystallizationVamsee Pamula; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Rapid parallel salivary immunoassays on a disposablePaul Yager; Fiscal Year: 2005..Finally, a versatile combined system will be designed and tested that will allow monitoring of samples by the two methods simultaneously. ..
- Neural control of abnormal movementTerence Sanger; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Creating Digital Partnerships for HealthAlwyn Cohall; Fiscal Year: 2008..Additionally, Digital Partners will assist the HHPC and its community advisory board in developing, implementing, evaluating and disseminating research findings. ..
- SLEEP HEART HEALTH STUDYHelaine Resnick; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
- Rapid Detection of Mycobacterium tuberculosisSusan Dorman; Fiscal Year: 2007..unreadable] [unreadable] Relevance: Results of these studies will improve our understanding of the laboratory performance and clinical benefit of this test, and lead to improved detection and treatment of TB. [unreadable] [unreadable]..
- Reducing the Disproportionate Burden of Orofacial InjuryVivek Shetty; Fiscal Year: 2007..abstract_text> ..
- Mycobacterium tuberculosis cell wall virulence factorsSusan Dorman; Fiscal Year: 2004..Finally, new information from the proposed self-contained pilot studies will serve as the foundation for future comprehensive dissection of macrophage response pathways affected by specific cell wall components. ..
- Lab-on-a-chip for multiplexed newborn screening of lysosomal storage disordersVamsee Pamula; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Towards drugs that prevent resistance to the HIV OI, TBDavid Alland; Fiscal Year: 2006..if embB306 mutations affect biosynthesis of LAM, capped LAM, arabinogalactan (AG) or other cell wall components in the presence and absence of EMB. ..
- Building a New Model for Diagnosis of ED Dizzy PatientsDavid Newman Toker; Fiscal Year: 2007..This research project and the research paradigms derived from it will form the nucleus of a career devoted to research in medical decision-making, causes of diagnostic errors, and methods to preventthem. ..
- TUBERCULOSIS GENOTYPING AND EVOLUTIONARY CONSORTIUMDavid Alland; Fiscal Year: 2005..4) To identify and validate an informative set of SNPs for worldwide evolutionary and epidemiological analyses. ..
- Nanoliter Lab-on-a-Chip for Rapid Parallel ImmunoassaysVamsee Pamula; Fiscal Year: 2006..Our eventual goal is to develop a nanoliter, rapid, fully automated, hand-held point-of-analysis/point-of-care analyzer that integrates clinical chemistry, molecular diagnostics, and immunoassays. [unreadable] [unreadable] [unreadable]..
- POPULATION BASED INVESTIGATIONS OF TUBERCULOSISDavid Alland; Fiscal Year: 2004..Studies of these sequence variations in clinical strains will be used to determine the associations between specific mutations and the phenotypes of infectivity and virulence. ..
- Detection of Select Agents in Single-Well AssaysDavid Alland; Fiscal Year: 2007..3. To develop PCR assays that utilize "color-triplet coding" to uniquely label as many as 56 different species-specific molecular beacons. ..
- Sample Processing Cartridges for Rapid PCR TB DetectionDavid Alland; Fiscal Year: 2008..The system will then be retested using a large number of clinical sputum specimens. Finally, we will develop complete documentation on the assay including production, and development reports. [unreadable] [unreadable] [unreadable]..