world health organization

Summary

Summary: A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.

Top Publications

  1. ncbi The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    James W Vardiman
    Department of Pathology, University of Chicago, IL, USA
    Blood 114:937-51. 2009
  2. doi Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)
    J Bousquet
    University Hospital and INSERM, Hopital Arnaud de Villeneuve, Montpellier, France
    Allergy 63:8-160. 2008
  3. pmc Data resource profile: the World Health Organization Study on global AGEing and adult health (SAGE)
    Paul Kowal
    WHO SAGE, Department of Health Statistics and Information Systems, World Health Organization, Geneva, Switzerland
    Int J Epidemiol 41:1639-49. 2012
  4. ncbi The World Health Organization's WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. A report from the WHOQOL group
    S M Skevington
    WHO Centre for the Study of Quality of Life, Department of Psychology, University of Bath, Bath, UK
    Qual Life Res 13:299-310. 2004
  5. ncbi An estimation of the global volume of surgery: a modelling strategy based on available data
    Thomas G Weiser
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA
    Lancet 372:139-44. 2008
  6. ncbi The new World Health Organization classification of lung tumours
    E Brambilla
    Service de Pathologie Cellulaire, Centre Hospitalier Universitaire de Grenoble, France
    Eur Respir J 18:1059-68. 2001
  7. ncbi The World Health Organization (WHO) classification of the myeloid neoplasms
    James W Vardiman
    Department of Pathology, University of Chicago, IL 60637, USA
    Blood 100:2292-302. 2002
  8. pmc An observational study of material durability of three World Health Organization-recommended long-lasting insecticidal nets in eastern Chad
    Richard Allan
    The MENTOR Initiative, Crawley, United Kingdom
    Am J Trop Med Hyg 87:407-11. 2012
  9. pmc Gestational diabetes and pregnancy outcomes--a systematic review of the World Health Organization (WHO) and the International Association of Diabetes in Pregnancy Study Groups (IADPSG) diagnostic criteria
    Eliana M Wendland
    Federal University of Health Sciences, Porto Alegre, Brazil
    BMC Pregnancy Childbirth 12:23. 2012
  10. ncbi The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI)
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Int J Methods Psychiatr Res 13:93-121. 2004

Detail Information

Publications260 found, 100 shown here

  1. ncbi The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    James W Vardiman
    Department of Pathology, University of Chicago, IL, USA
    Blood 114:937-51. 2009
    Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society for Hematopathology, published a revised and updated edition of the WHO Classification of Tumors of the ..
  2. doi Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)
    J Bousquet
    University Hospital and INSERM, Hopital Arnaud de Villeneuve, Montpellier, France
    Allergy 63:8-160. 2008
  3. pmc Data resource profile: the World Health Organization Study on global AGEing and adult health (SAGE)
    Paul Kowal
    WHO SAGE, Department of Health Statistics and Information Systems, World Health Organization, Geneva, Switzerland
    Int J Epidemiol 41:1639-49. 2012
    ..The World Health Organization's Study on global AGEing and adult health (SAGE) aims to address the gap in reliable data and scientific ..
  4. ncbi The World Health Organization's WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. A report from the WHOQOL group
    S M Skevington
    WHO Centre for the Study of Quality of Life, Department of Psychology, University of Bath, Bath, UK
    Qual Life Res 13:299-310. 2004
    ..These results indicate that overall, the WHOQOL-BREF is a sound, cross-culturally valid assessment of QOL, as reflected by its four domains: physical, psychological, social and environment...
  5. ncbi An estimation of the global volume of surgery: a modelling strategy based on available data
    Thomas G Weiser
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA
    Lancet 372:139-44. 2008
    ..We estimated the number of major operations undertaken worldwide, described their distribution, and assessed the importance of surgical care in global public-health policy...
  6. ncbi The new World Health Organization classification of lung tumours
    E Brambilla
    Service de Pathologie Cellulaire, Centre Hospitalier Universitaire de Grenoble, France
    Eur Respir J 18:1059-68. 2001
    ....
  7. ncbi The World Health Organization (WHO) classification of the myeloid neoplasms
    James W Vardiman
    Department of Pathology, University of Chicago, IL 60637, USA
    Blood 100:2292-302. 2002
    A World Health Organization (WHO) classification of hematopoietic and lymphoid neoplasms has recently been published...
  8. pmc An observational study of material durability of three World Health Organization-recommended long-lasting insecticidal nets in eastern Chad
    Richard Allan
    The MENTOR Initiative, Crawley, United Kingdom
    Am J Trop Med Hyg 87:407-11. 2012
    ..These results provide the first comparative data on LLIN material durability to guide procurement and replacement practice, and to inform urgently needed changes in LLIN international minimum specifications and product standards...
  9. pmc Gestational diabetes and pregnancy outcomes--a systematic review of the World Health Organization (WHO) and the International Association of Diabetes in Pregnancy Study Groups (IADPSG) diagnostic criteria
    Eliana M Wendland
    Federal University of Health Sciences, Porto Alegre, Brazil
    BMC Pregnancy Childbirth 12:23. 2012
    ..are being used for the diagnosis of gestational diabetes (GDM), those recommended over the years by the World Health Organization (WHO), and those recently recommended by the International Association for Diabetes in Pregnancy Study ..
  10. ncbi The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI)
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Int J Methods Psychiatr Res 13:93-121. 2004
    This paper presents an overview of the World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) and a discussion of the methodological research on ..
  11. ncbi Resources for mental health: scarcity, inequity, and inefficiency
    Shekhar Saxena
    World Health Organization, Geneva, Switzerland
    Lancet 370:878-89. 2007
    ..Scarcity of available resources, inequities in their distribution, and inefficiencies in their use pose the three main obstacles to better mental health, especially in low-income and middle-income countries...
  12. ncbi Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma
    Jean Bousquet
    University Hospital, Hopital Arnaud de Villeneuve, Montpellier, France
    J Allergy Clin Immunol 126:926-38. 2010
    ..A World Health Organization meeting was convened April 5-6, 2009, to propose a uniform definition of severe asthma...
  13. pmc Evaluation of the traditional and revised WHO classifications of Dengue disease severity
    Federico Narvaez
    Infectious Diseases Unit, Hospital Infantil Manuel de Jesus Rivera, Managua, Nicaragua
    PLoS Negl Trop Dis 5:e1397. 2011
    ..The long-standing World Health Organization (WHO) dengue classification and management scheme was recently revised, replacing DF, Dengue Hemorrhagic ..
  14. ncbi The World Health Organization Adult ADHD Self-Report Scale (ASRS): a short screening scale for use in the general population
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Psychol Med 35:245-56. 2005
    A self-report screening scale of adult attention-deficit/hyperactivity disorder (ADHD), the World Health Organization (WHO) Adult ADHD Self-Report Scale (ASRS) was developed in conjunction with revision of the WHO Composite International ..
  15. ncbi The World Health Organization Health and Work Performance Questionnaire (HPQ)
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    J Occup Environ Med 45:156-74. 2003
    This report describes the World Health Organization Health and Work Performance Questionnaire (HPQ), a self-report instrument designed to estimate the workplace costs of health problems in terms of reduced job performance, sickness ..
  16. ncbi The world report on violence and health
    Etienne G Krug
    Injuries and Violence Prevention Department, Non Communicable Diseases and Mental Health, WHO, Geneva, Switzerland
    Lancet 360:1083-8. 2002
    ..The launch of the report will be followed by a 1-year Global Campaign on Violence Prevention, focusing on implementation of the recommendations. This article summarises some of the main points of the world report...
  17. pmc Developing the World Health Organization Disability Assessment Schedule 2.0
    T Bedirhan Ustun
    World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland
    Bull World Health Organ 88:815-23. 2010
    To describe the development of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2...
  18. pmc Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    PLoS Med 7:e1000382. 2010
    The new 2010 World Health Organization (WHO) HIV treatment guidelines recommend earlier antiretroviral therapy (ART) initiation (CD4<350 cells/µl instead of CD4<200 cells/µl), multiple sequential ART regimens, and replacement of ..
  19. pmc HIV drug resistance early warning indicators in cohorts of individuals starting antiretroviral therapy between 2004 and 2009: World Health Organization global report from 50 countries
    Diane E Bennett
    US Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Infect Dis 54:S280-9. 2012
    The World Health Organization developed a set of human immunodeficiency virus drug resistance (HIVDR) early warning indicators (EWIs) to assess antiretroviral therapy clinic and program factors associated with HIVDR...
  20. pmc Cost-effectiveness of antiretroviral regimens in the World Health Organization's treatment guidelines: a South African analysis
    Eran Bendavid
    Division of General Internal Medicine, Stanford University, Stanford, USA
    AIDS 25:211-20. 2011
    the World Health Organization (WHO) recently changed its first-line antiretroviral treatment guidelines in resource-limited settings. The cost-effectiveness of the new guidelines is unknown.
  21. ncbi Using the World Health Organization Health and Work Performance Questionnaire (HPQ) to evaluate the indirect workplace costs of illness
    Ronald C Kessler
    Department of Health Care Polity, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Occup Environ Med 46:S23-37. 2004
    ..in estimating the indirect workplace costs of illness from data obtained in employee surveys using the World Health Organization Health and Work Performance Questionnaire (HPQ)...
  22. ncbi The World Health Organization's global strategy for prevention and assessment of HIV drug resistance
    Diane E Bennett
    World Health Organization, Geneva, Switzerland
    Antivir Ther 13:1-13. 2008
    ..The World Health Organization (WHO) recommends a minimum-resource strategy for prevention and assessment of HIVDR in resource-limited ..
  23. ncbi From malaria control to eradication: The WHO perspective
    Kamini Mendis
    Global Malaria Programme, World Health Organization, Geneva, Switzerland
    Trop Med Int Health 14:802-9. 2009
    ..This paper summarizes the outcomes of a World Health Organization's expert meeting on the feasibility of such a goal...
  24. ncbi International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009
    F Zegers-Hochschild
    Unit of Reproductive Medicine, Clinicas las Condes, Santiago, Chile
    Fertil Steril 92:1520-4. 2009
    ....
  25. ncbi Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis
    J A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UK
    Bone 27:585-90. 2000
    ..aim of this study was to examine the utility of relative risks of hip fracture in men and women using World Health Organization (WHO) diagnostic criteria for low bone mass and osteoporosis...
  26. pmc Utilities and limitations of the World Health Organization 2009 warning signs for adult dengue severity
    Tun Linn Thein
    Communicable Disease Centre, Tan Tock Seng Hospital, Singapore, Singapore
    PLoS Negl Trop Dis 7:e2023. 2013
    In 2009, the World Health Organization (WHO) proposed seven warning signs (WS) as criteria for hospitalization and predictors of severe dengue (SD)...
  27. ncbi The WHO Multicentre Growth Reference Study: planning, study design, and methodology
    Mercedes de Onis
    Department of Nutrition, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    Food Nutr Bull 25:S15-26. 2004
    The World Health Organization (WHO) Multicentre Growth Reference Study (MGRS) is a community-based, multicountry project to develop new growth references for infants and young children...
  28. pmc Dengue--how best to classify it
    Anon Srikiatkhachorn
    Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Clin Infect Dis 53:563-7. 2011
    ..Since the 1970s, clinical dengue has been classified according to the World Health Organization guideline as dengue fever and dengue hemorrhagic fever...
  29. pmc Pre-validation of the WHO organ dysfunction based criteria for identification of maternal near miss
    Jose G Cecatti
    Obstetric Unit, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Sao Paulo, Brazil
    Reprod Health 8:22. 2011
    ..To evaluate the performance of the WHO criteria for defining maternal near miss and identifying deaths among cases of severe maternal morbidity (SMM) admitted for intensive care...
  30. ncbi Recommendations for surveillance of transmitted HIV drug resistance in countries scaling up antiretroviral treatment
    Diane E Bennett
    World Health Organization, Geneva, Switzerland
    Antivir Ther 13:25-36. 2008
    The World Health Organization (WHO) HIV drug resistance (HIVDR) threshold survey method was developed for surveillance of transmitted HIVDR in resource-limited countries...
  31. ncbi The WHO dengue classification and case definitions: time for a reassessment
    Jacqueline L Deen
    International Vaccine Institute, Kwanak PO Box 14, Seoul, Republic of Korea
    Lancet 368:170-3. 2006
  32. ncbi The World Health Organization hand hygiene observation method
    Hugo Sax
    Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, 1211 Geneva 14, Switzerland
    Am J Infect Control 37:827-34. 2009
    ..Within the framework of the World Health Organization's (WHO) First Global Patient Safety Challenge known as "Clean Care is Safer Care," an evidence-based, ..
  33. ncbi Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel
    Ayalew Tefferi
    Mayo Clinic, Rochester, MN 55905, USA
    Blood 110:1092-7. 2007
    ..Accordingly, revision of the current World Health Organization (WHO) diagnostic criteria for PV, ET, and PMF is warranted; JAK2 mutation analysis should be listed as a ..
  34. ncbi Global monitoring of Salmonella serovar distribution from the World Health Organization Global Foodborne Infections Network Country Data Bank: results of quality assured laboratories from 2001 to 2007
    Rene S Hendriksen
    National Food Institute, WHO Collaborating Centre for Antimicrobial Resistance in Foodborne Pathogens and Community Reference Laboratory for Antimicrobial Resistance, Technical University of Denmark, Copenhagen, Denmark
    Foodborne Pathog Dis 8:887-900. 2011
    ..Salmonella isolated from humans from 2001 to 2007 in laboratories from 37 countries that participated in World Health Organization Global Foodborne Infections Network and demonstrated serotyping proficiency in the Global Foodborne ..
  35. ncbi The International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) Revised Glossary on ART Terminology, 2009
    F Zegers-Hochschild
    Unit of Reproductive Medicine, Clinicas las Condes, Santiago, Chile
    Hum Reprod 24:2683-7. 2009
    ....
  36. pmc Twelve-month prevalence of and risk factors for suicide attempts in the World Health Organization World Mental Health Surveys
    Guilherme Borges
    National Institute of Psychiatry, Mexico City, Mexico
    J Clin Psychiatry 71:1617-28. 2010
    ....
  37. ncbi Leishmaniasis in the World Health Organization Eastern Mediterranean Region
    Jose A Ruiz Postigo
    World Health Organization, Eastern Mediterranean Regional Office, Cairo, Egypt
    Int J Antimicrob Agents 36:S62-5. 2010
    Leishmaniasis represents a major public health problem in the Eastern Mediterranean Region (EMR) of the World Health Organization (WHO). Cutaneous and visceral leishmaniasis are mainly seen in 14 of the 22 countries of the region...
  38. ncbi National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study
    Kelly J Hunt
    Department of Medicine, University of Texas Health Science Center at San Antonio, 78229 3900, USA
    Circulation 110:1251-7. 2004
    ..the relation between the MetS, using both the National Cholesterol Education Program (NCEP) and the World Health Organization definitions, and all-cause and cardiovascular mortality in San Antonio Heart Study participants enrolled ..
  39. ncbi Concordance of the Composite International Diagnostic Interview Version 3.0 (CIDI 3.0) with standardized clinical assessments in the WHO World Mental Health surveys
    Josep Maria Haro
    Int J Methods Psychiatr Res 15:167-80. 2006
    ..The validity of the CIDI is likely to be under-estimated in these comparisons due to the fact that the reliability of the SCID diagnoses, which is presumably less than perfect, sets a ceiling on maximum CIDI-SCID concordance...
  40. pmc Mobile health applications for the most prevalent conditions by the World Health Organization: review and analysis
    Borja Martínez-Pérez
    University of Valladolid, Department of Signal Theory and Communications, and Telematics Engineering, University of Valladolid, Valladolid, Spain
    J Med Internet Res 15:e120. 2013
    ..Every aid for health care is welcome and necessary as shown by the more than 50 million estimated deaths caused by illnesses or health conditions in 2008. Some of these conditions have additional importance depending on their prevalence...
  41. ncbi World Health Organization reference values for human semen characteristics
    Trevor G Cooper
    Centre of Reproductive Medicine and Andrology of the University, Domagkstrasse 11, Munster, Germany
    Hum Reprod Update 16:231-45. 2010
    ..Reference intervals for values of semen parameters from a fertile population could provide data from which prognosis of fertility or diagnosis of infertility can be extrapolated...
  42. ncbi Oral cancer prevention and control--the approach of the World Health Organization
    Poul Erik Petersen
    Global Oral Health Programme, World Health Organization, 20 Avenue Appia, CH1211 Geneva 27, Switzerland
    Oral Oncol 45:454-60. 2009
    ..who.int/oral_health...
  43. pmc Cost-effectiveness of World Health Organization 2010 guidelines for prevention of mother-to-child HIV transmission in Zimbabwe
    Andrea L Ciaranello
    Medical Practice Evaluation Center, Divisions of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Infect Dis 56:430-46. 2013
    In 2010, the World Health Organization (WHO) released revised guidelines for prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT)...
  44. ncbi World Health Organization definition of myocardial infarction: 2008-09 revision
    Shanthi Mendis
    Chronic Disease Prevention and Management, World Health Organization, Geneva, Switzerland
    Int J Epidemiol 40:139-46. 2011
    ..WHO has played a leading role in the formulation and promulgation of standard criteria for the diagnosis of coronary heart disease and myocardial infarction since early 1970s...
  45. ncbi ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients
    Yau Jiunn Lee
    Department of Clinical Research, Pingtung Christian Hospital, Pingtung, Taiwan
    Diabetes Care 25:1002-8. 2002
    ....
  46. ncbi The prevalence of maternal near miss: a systematic review
    O Tuncalp
    Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BJOG 119:653-61. 2012
    ..Severe maternal morbidity or 'near miss' is a promising indicator to improve quality of obstetric care...
  47. ncbi Classifying dengue: a review of the difficulties in using the WHO case classification for dengue haemorrhagic fever
    Shibani Bandyopadhyay
    Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Trop Med Int Health 11:1238-55. 2006
    ..Dengue has extended to different tropical areas and older age groups. Variations from the original description of dengue manifestations are being reported...
  48. ncbi Prospects for worldwide tuberculosis control under the WHO DOTS strategy. Directly observed short-course therapy
    C Dye
    Global Tuberculosis Programme, WHO, Geneva, Switzerland
    Lancet 352:1886-91. 1998
    ..WHO advocates the use of directly observed treatment with a short-course drug regimen as part of the DOTS strategy, but the potential effect of this strategy worldwide has not been investigated...
  49. pmc Dengue hemorrhagic fever: the sensitivity and specificity of the world health organization definition for identification of severe cases of dengue in Thailand, 1994-2005
    Anon Srikiatkhachorn
    University of Massachusetts Medical School, Worcester, MA 01655, USA
    Clin Infect Dis 50:1135-43. 2010
    Dengue virus infection causes a spectrum of clinical manifestations, usually classified according to the World Health Organization (WHO) guidelines into dengue fever (DF) and dengue hemorrhagic fever (DHF)...
  50. ncbi Physical activity in 22 African countries: results from the World Health Organization STEPwise approach to chronic disease risk factor surveillance
    Regina Guthold
    Department of Chronic Diseases and Health Promotion, WHO, Geneva, Switzerland
    Am J Prev Med 41:52-60. 2011
    ..Baseline physical activity data are needed to effectively plan programs and policies to prevent noncommunicable diseases, but for many African countries these data are lacking...
  51. ncbi WHO antenatal care randomised trial for the evaluation of a new model of routine antenatal care
    J Villar
    UNDP UNFPA WHO World Bank Special Programme of Research, Development, and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Health Organisation, Geneva, Switzerland
    Lancet 357:1551-64. 2001
    ..We undertook a multicentre randomised controlled trial that compared the standard model of antenatal care with a new model that emphasises actions known to be effective in improving maternal or neonatal outcomes and has fewer clinic visits...
  52. pmc The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds
    Martin van den Berg
    World Health Organization Collaborating Centre for Research on Environmental Health Risk Assessment and Institute for Risk Assessment Sciences, Science and University Medical Center, Universiteit Utrecht, The Netherlands
    Toxicol Sci 93:223-41. 2006
    In June 2005, a World Health Organization (WHO)-International Programme on Chemical Safety expert meeting was held in Geneva during which the toxic equivalency factors (TEFs) for dioxin-like compounds, including some polychlorinated ..
  53. ncbi Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms
    A Tefferi
    Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Leukemia 22:14-22. 2008
    The 2001 World Health Organization (WHO) treatise on the classification of hematopoietic tumors lists chronic myeloproliferative diseases (CMPDs) as a subdivision of myeloid neoplasms that includes the four classic myeloproliferative ..
  54. ncbi The World Health Organization histologic classification system reflects the oncologic behavior of thymoma: a clinical study of 273 patients
    Meinoshin Okumura
    Division of General Thoracic Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Cancer 94:624-32. 2002
    ..an agreement on the universal classification system for thymic epithelial tumors was achieved by the World Health Organization (WHO) in 1999...
  55. ncbi World Health Organization ranking of antimicrobials according to their importance in human medicine: A critical step for developing risk management strategies for the use of antimicrobials in food production animals
    Peter Collignon
    Microbiology Department, The Canberra Hospital, Australian National University, Woden, Australia
    Clin Infect Dis 49:132-41. 2009
    ..The World Health Organization has developed and applied criteria to rank antimicrobials according to their relative importance in ..
  56. pmc Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults
    Shera Chaterji
    Program in Emerging Infectious Diseases, Duke National University of Singapore NUS Graduate Medical School, Singapore
    Am J Trop Med Hyg 84:224-8. 2011
    ..We evaluated the sensitivity and specificity of the 1997 and 2009 World Health Organization (WHO) dengue classification schemes and the NS1 strip test in acute sera from 154 virologically ..
  57. pmc WHO and UNICEF estimates of national infant immunization coverage: methods and processes
    Anthony Burton
    Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 87:535-41. 2009
    ..These country-specific estimates, available from 1980 onward, are updated annually...
  58. ncbi Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease
    Eloi Marijon
    Universite Paris Descartes, AP HP, Hopital Europeen Georges Pompidou, France
    Circulation 120:663-8. 2009
    ..The currently utilized World Health Organization (WHO) criteria for echocardiographic diagnosis of subclinical RHD emphasize the presence of pathological ..
  59. ncbi Effectiveness of heptavalent pneumococcal conjugate vaccine in children younger than 5 years of age for prevention of pneumonia: updated analysis using World Health Organization standardized interpretation of chest radiographs
    John Hansen
    Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
    Pediatr Infect Dis J 25:779-81. 2006
    A World Health Organization (WHO) working group in 2001 developed a method for standardizing interpretation of chest radiographs in children for epidemiologic purposes...
  60. pmc Methodological considerations in implementing the WHO Global Survey for Monitoring Maternal and Perinatal Health
    Archana Shah
    Department of Making Pregnancy Safer, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 86:126-31. 2008
    ..To set up a global system for monitoring maternal and perinatal health in 54 countries worldwide...
  61. pmc Childhood predictors of adult attention-deficit/hyperactivity disorder: results from the World Health Organization World Mental Health Survey Initiative
    Carmen Lara
    Department of Psychiatry, Autonomous University of Puebla, Puebla, Mexico
    Biol Psychiatry 65:46-54. 2009
    ..Although it is known that childhood attention-deficit/hyperactivity disorder (ADHD) often persists into adulthood, childhood predictors of this persistence have not been widely studied...
  62. ncbi Global policy for improvement of oral health in the 21st century--implications to oral health research of World Health Assembly 2007, World Health Organization
    Poul Erik Petersen
    World Health Organization, Department of Chronic Disease and Health Promotion, Geneva, Switzerland
    Community Dent Oral Epidemiol 37:1-8. 2009
    The World Health Organization (WHO) Global Oral Health Programme has worked hard over the past 5 years to increase the awareness of oral health worldwide as oral health is important component of general health and quality of life...
  63. ncbi The World Health Organization Guidelines on Hand Hygiene in Health Care and their consensus recommendations
    Didier Pittet
    Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
    Infect Control Hosp Epidemiol 30:611-22. 2009
    The World Health Organization's Guidelines on Hand Hygiene in Health Care have been issued by WHO Patient Safety on 5 May 2009 on the occasion of the launch of the Save Lives: Clean Your Hands initiative...
  64. pmc Cross-national associations between gender and mental disorders in the World Health Organization World Mental Health Surveys
    Soraya Seedat
    Medical Research Council Research Unit on Anxiety and Stress Disorder, Cape Town, South Africa
    Arch Gen Psychiatry 66:785-95. 2009
    ..The gender roles hypothesis suggests that these differences narrow as the roles of women and men become more equal...
  65. pmc Surfing the web during pandemic flu: availability of World Health Organization recommendations on prevention
    Francesco Gesualdo
    Ospedale Pediatrico Bambino Gesu, Rome, Italy
    BMC Public Health 10:561. 2010
    People often search for information on influenza A(H1N1)v prevention on the web. The extent to which information found on the Internet is consistent with recommendations issued by the World Health Organization is unknown.
  66. pmc British American Tobacco on Facebook: undermining Article 13 of the global World Health Organization Framework Convention on Tobacco Control
    Becky Freeman
    A27 School of Public Health, Room 129A, University of Sydney, Sydney, NSW 2006, Australia
    Tob Control 19:e1-9. 2010
    The World Health Organization Framework Convention on Tobacco Control (WHO FCTC) bans all forms of tobacco advertising, promotion and sponsorship...
  67. pmc World Health Organization discontinues its drinking-water guideline for manganese
    Seth H Frisbie
    Department of Chemistry and Biochemistry, Norwich University, Northfield, Vermont, USA
    Environ Health Perspect 120:775-8. 2012
    The World Health Organization (WHO) released the fourth edition of Guidelines for Drinking-Water Quality in July 2011...
  68. ncbi World Health Organization surveys to monitor HIV drug resistance prevention and associated factors in sentinel antiretroviral treatment sites
    Michael R Jordan
    Tufts University School of Medicine, Boston, MA, USA
    Antivir Ther 13:15-23. 2008
    The World Health Organization (WHO) estimates that >2 million people will have started antiretroviral therapy (ART) by the end of 2006...
  69. pmc Update on World Health Organization HIV drug resistance prevention and assessment strategy: 2004-2011
    M R Jordan
    World Health Organization, Geneva, Switzerland
    Clin Infect Dis 54:S245-9. 2012
    The HIV drug resistance (HIVDR) prevention and assessment strategy, developed by the World Health Organization (WHO) in partnership with HIVResNet, includes monitoring of HIVDR early warning indicators, surveys to assess acquired and ..
  70. pmc Implications of adopting the WHO 2006 Child Growth Standard in the UK: two prospective cohort studies
    C Wright
    Division of Developmental Medicine, University of Glasgow, Glasgow, UK
    Arch Dis Child 93:566-9. 2008
    ..The WHO 2006 Child Growth Standard is based on data from international optimally nourished breastfed infants from birth to age 5 years...
  71. ncbi Cost-effectiveness of new WHO recommendations for prevention of mother-to-child transmission of HIV in a resource-limited setting
    Maunank Shah
    Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    AIDS 25:1093-102. 2011
    ....
  72. pdf Dengue classification: current WHO vs. the newly suggested classification for better clinical application?
    Siripen Kalayanarooj
    Dengue Unit, Queen Sirikit National Institute of Child Health, College of Medicine, Rangsit University, Bangkok, Thailand
    J Med Assoc Thai 94:S74-84. 2011
    ..This new classification classifies dengue into dengue (D), dengue with warning signs (DW) and severe dengue (SD)...
  73. ncbi Evaluation of the World Health Organization algorithm for the diagnosis of HIV-associated sputum smear-negative tuberculosis
    D Wilson
    Department of Medicine, Edendale Hospital, Pietermaritzburg, South Africa
    Int J Tuberc Lung Dis 15:919-24. 2011
    Outcomes from the World Health Organization's (WHO's) recommendations for the diagnosis of smear-negative tuberculosis (SNTB) in high human immunodeficiency virus prevalence settings are unknown.
  74. ncbi Use of World Health Organization and CDC growth charts for children aged 0-59 months in the United States
    Laurence M Grummer-Strawn
    Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, USA
    MMWR Recomm Rep 59:1-15. 2010
    In April 2006, the World Health Organization (WHO) released new international growth charts for children aged 0-59 months...
  75. ncbi Hot spots in a wired world: WHO surveillance of emerging and re-emerging infectious diseases
    D L Heymann
    World Health Organization, Communicable Disease Programmes, Geneva, Switzerland
    Lancet Infect Dis 1:345-53. 2001
    ..About 65% of the world's first news about infectious disease events now comes from informal sources, including press reports and the internet...
  76. ncbi The 2004 World Health Organization classification of lung tumors
    Mary Beth Beasley
    Providence Portland Medical Center, Department of Pathology, Portland, OR, USA
    Semin Roentgenol 40:90-7. 2005
  77. ncbi Utility of childhood BMI in the prediction of adulthood disease: comparison of national and international references
    Ian Janssen
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada K7L 3N6
    Obes Res 13:1106-15. 2005
    ....
  78. ncbi Diagnosis of antiretroviral therapy failure in Malawi: poor performance of clinical and immunological WHO criteria
    Joep J G van Oosterhout
    Department of Medicine, University of Malawi College of Medicine, Blantyre, Malawi
    Trop Med Int Health 14:856-61. 2009
    ..We wanted to study the impact of only using clinical and immunological monitoring on the diagnosis of virological ART failure under routine circumstances...
  79. pmc Evaluation of the 2007 WHO guideline to improve the diagnosis of tuberculosis in ambulatory HIV-positive adults
    Olivier Koole
    Institute of Tropical Medicine, Antwerp, Belgium
    PLoS ONE 6:e18502. 2011
    ..In 2007 WHO issued a guideline to improve the diagnosis of smear-negative and extrapulmonary tuberculosis (EPTB) in HIV-positive patients. This guideline relies heavily on the acceptance of HIV-testing and availability of chest X-rays...
  80. ncbi Correlating genetic aberrations with World Health Organization-defined histology and stage across the spectrum of thymomas
    Masayoshi Inoue
    Institute of Pathology, University of Wurzburg, D 97080 Wurzburg, Germany
    Cancer Res 63:3708-15. 2003
    ..However, other findings imply that types A and AB are biologically distinct from the others, any potential invasiveness being severely restricted by a medullary commitment in the precursor cell undergoing neoplastic transformation...
  81. ncbi Apolipoprotein B and A-I values in 147576 Swedish males and females, standardized according to the World Health Organization-International Federation of Clinical Chemistry First International Reference Materials
    I Jungner
    CALAB Research and CALAB Medical Laboratories, S t Göran Hospital, Stockholm, Sweden
    Clin Chem 44:1641-9. 1998
    ....
  82. pmc Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal
    D M Burns
    UCSD School of Medicine, San Diego, California, USA
    Tob Control 17:132-41. 2008
  83. ncbi Method of delivery and pregnancy outcomes in Asia: the WHO global survey on maternal and perinatal health 2007-08
    Pisake Lumbiganon
    Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Lancet 375:490-9. 2010
    ....
  84. pmc Can clinical signs of trachoma be used after multiple rounds of mass antibiotic treatment to indicate infection?
    Beatriz Munoz
    Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, Maryland, USA
    Invest Ophthalmol Vis Sci 52:8806-10. 2011
    To evaluate combinations of clinical signs, using a modified World Health Organization (WHO) grading scheme, to predict a very low prevalence of infection at the community level after at least three rounds of mass drug administration (..
  85. pmc Trachomatous trichiasis and its management in endemic countries
    Saul N Rajak
    International Centre for Eye Health, London School of Hygiene and Tropical Medicine, London, UK
    Surv Ophthalmol 57:105-35. 2012
    ..We examine the principles of clinical management, treatment options, and the challenging issues of providing the quantity and quality of surgery that is needed in resource-poor settings...
  86. pmc Should this event be notified to the World Health Organization? Reliability of the international health regulations notification assessment process
    Thomas Haustein
    Infection Control Programme, University of Geneva Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Bull World Health Organ 89:296-303. 2011
    ..To investigate the reliability of the public health event notification assessment process under the International Health Regulations (2005) (IHR)...
  87. ncbi Status of global virologic surveillance for rubella viruses
    Emily S Abernathy
    Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 204:S524-32. 2011
    ..Current challenges are discussed...
  88. pmc Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008
    Vanya Delgermaa
    Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Iseigaoka 1 1, Yahatanishiku, Kitakyushu City, Fukuoka Prefecture 807 8555, Japan
    Bull World Health Organ 89:716-24, 724A-724C. 2011
    ..To carry out a descriptive analysis of mesothelioma deaths reported worldwide between 1994 and 2008...
  89. ncbi Determining prognosis in patients with pancreatic endocrine neoplasms: can the WHO classification system be simplified?
    Cristina R Ferrone
    Department of Surgery, Memorial Sloan Kettering Cancer Center, Howard 1223, 1275 York Ave, New York, NY 10021, USA
    J Clin Oncol 25:5609-15. 2007
    ..This study compares the prognostic value of a simplified staging and grading system with the WHO system in a large single-institution study...
  90. ncbi Prevalence of metabolic syndrome by the Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions and their association with coronary heart disease in an elderly Iranian population
    Farzad Hadaegh
    Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, PO Box 19395 4763, Tehran, Iran
    Ann Acad Med Singapore 38:142-9. 2009
    ..To determine the prevalence of the metabolic syndrome (MS) in an Iranian elderly population and show its association with coronary heart disease (CHD)...
  91. pmc Compliance of clinical trial registries with the World Health Organization minimum data set: a survey
    Lorenzo P Moja
    Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Trials 10:56. 2009
    ..Committee of Medical Journal Editors has required that trials be registered in accordance with the World Health Organization (WHO) minimum dataset, in order to be considered for publication...
  92. pmc Early cannabis use and estimated risk of later onset of depression spells: Epidemiologic evidence from the population-based World Health Organization World Mental Health Survey Initiative
    Ron de Graaf
    Department of Epidemiology, Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
    Am J Epidemiol 172:149-59. 2010
    ..depression spell, using data on 85,088 subjects from 17 countries participating in the population-based World Health Organization World Mental Health Survey Initiative (2001-2005)...
  93. pmc Development of lifetime comorbidity in the World Health Organization world mental health surveys
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Arch Gen Psychiatry 68:90-100. 2011
    ..Although numerous studies have examined the role of latent variables in the structure of comorbidity among mental disorders, none has examined their role in the development of comorbidity...
  94. pmc Elimination of neglected tropical diseases in the South-East Asia Region of the World Health Organization
    Jai P Narain
    Department of Communicable Diseases, World Health Organization Regional Office for South East Asia, IP Estate, Mahatama Gandhi Road, New Delhi 110002, India
    Bull World Health Organ 88:206-10. 2010
    ..which affect the very poor, pose a major public health problem in the South-East Asia Region of the World Health Organization (WHO)...
  95. pmc Use of mental health services for anxiety, mood, and substance disorders in 17 countries in the WHO world mental health surveys
    Philip S Wang
    Division of Services and Intervention Research, National Institute of Mental Health, Rockville, MD, USA
    Lancet 370:841-50. 2007
    ..We describe mental health care in 17 countries participating in the WHO world mental health (WMH) survey initiative and examine unmet needs for treatment...
  96. ncbi The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms
    James W Vardiman
    University of Chicago Medical Center, 5841 South Maryland Avenue, MC0008, Chicago, IL 60637, United States
    Chem Biol Interact 184:16-20. 2010
    The World Health Organization (WHO) classification of myeloid and lymphoid neoplasms utilizes morphology, immunophenotype, genetics and clinical features to define disease entities of clinical significance...
  97. pmc The 2007 WHO classification of tumours of the central nervous system
    David N Louis
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Acta Neuropathol 114:97-109. 2007
    The fourth edition of the World Health Organization (WHO) classification of tumours of the central nervous system, published in 2007, lists several new entities, including angiocentric glioma, papillary glioneuronal tumour, rosette-..
  98. pmc Children with severe malnutrition: can those at highest risk of death be identified with the WHO protocol?
    Kathryn Maitland
    Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
    PLoS Med 3:e500. 2006
    ..with early (<48 h) and late in-hospital death in children with severe malnutrition with the aim of identifying admission features that could distinguish a high-risk group in relation to the World Health Organization (WHO) guidelines.
  99. ncbi Comparison of the WHO child growth standards and the CDC 2000 growth charts
    Mercedes de Onis
    Department of Nutrition, World Health Organization, Geneva, Switzerland
    J Nutr 137:144-8. 2007
    ..S. national guidelines that recommend breast-feeding as the optimal source of nutrition during infancy...
  100. ncbi Evaluation of the World Health Organization standard tourniquet test and a modified tourniquet test in the diagnosis of dengue infection in Viet Nam
    Xuan Thanh Phuong Cao
    Dong Nai Paediatric Hospital, Bien Hoa, Dong Nai Province, Viet Nam
    Trop Med Int Health 7:125-32. 2002
    A positive tourniquet test is one of several clinical parameters considered by the World Health Organization to be important in the diagnosis of dengue haemorrhagic fever, but no formal evaluation of the test has been undertaken...
  101. ncbi Infection control as a major World Health Organization priority for developing countries
    D Pittet
    Infection Control Programme, University of Geneva Hospitals, Geneva, Switzerland
    J Hosp Infect 68:285-92. 2008
    ..A growing awareness of this problem prompted the World Health Organization to promote the creation of the World Alliance for Patient Safety...

Research Grants77

  1. CRF-Oxytocin Interaction in the Regulation of Stress and Affect
    Joanna Dabrowska; Fiscal Year: 2013
    According to the World Health Organization depression affects 121 million people worldwide. Chronic stress and thus increased corticotrophin releasing factor (CRF) signaling is indicated as a potential risk factor for depression...
  2. Retinoid Metabolism and Alcohol Induced Disease
    William S Blaner; Fiscal Year: 2010
    ..by applicant): Estimates of death rates caused by chronic alcohol consumption, published in 2004 by the World Health Organization, indicate that alcohol accounts for approximately 1.8 million deaths per year...
  3. Remodeling Neuronal Chromatin in Mouse Models for Depression
    Schahram Akbarian; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: According to estimates of the World Health Organization, depression could become the second most frequent cause of illness-induced disability by 2020...
  4. Nanopolymersomes for Transcutaneous Co-Delivery of Vaccine Antigens and Adjuvants
    PAUL CAMILLE TUMEH; Fiscal Year: 2013
    ..The World Health Organization estimates that 5-10% percent of the 16 billion injections administered worldwide each year are given for ..
  5. Fatty acid related regulation of enteric infectious disease
    FREDRICK JON KULL; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): According to the World Health Organization, diarrhea caused by enteric infections affects some four billion individuals annually throughout the world, resulting in an estimated four million to six ..
  6. Biochemistry and Function of a Novel Bacterial Photosensory Two-Component System
    MELISSA MARKS; Fiscal Year: 2010
    ..According to the World Health Organization, over 130,000 cases of cholera (Vibrio cholerae) and 17 million cases of Typhoid fever (Salmonella typhi)..
  7. Mechanisms of Heme Transport in Macrophages
    CARINE CARINE WHITE; Fiscal Year: 2012
    ..According to the World Health Organization, four out of five people in the world may be iron deficient, making nutritional iron deficiency one of ..
  8. Mechanisms of Neutralizing Antibody Resistance in Chronic HCV and HIV Infection
    JUSTIN RICHARD BAILEY; Fiscal Year: 2013
    ..Relevance The World Health Organization estimates there are 170 million persons with hepatitis C virus (HCV) infection worldwide, and in most ..
  9. Mechanism(s) of Hepatocyte Transformation by the Hepatitis B Virus X Protein
    Ourania M Andrisani; Fiscal Year: 2013
    ..Despite the HBV vaccine, the World Health Organization reports 400 million people are chronically infected with HBV...
  10. Transcriptional Regulation of Natriuetic Sensitivity in Diabetes Mellitus
    PATIENCE O OBIH; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Estimates from the World Health Organization indicate there are some 130 million diagnosed diabetics in the world, a figure that is predicted to increase to 300 million by 2025...
  11. Tadalafil for Pulmonary Hypertension Associated with Chronic Lung Disease
    SHARON IRENE SMITH ROUNDS; Fiscal Year: 2013
    ..PDE-5 inhibitors are recommended for World Health Organization (WHO) Group 1 PH but there is no evidence based recommendation supporting the use of these inhibitors in ..
  12. Durable Visible Light-activated Antivral Coatings for Fabrics Used for Personal P
    JOSEF STEPHAN SCHNEIDER; Fiscal Year: 2011
    ..PUBLIC HEALTH RELEVANCE: Influenza spreads rapidly throughout the world in seasonal epidemics. The World Health Organization estimates that influenza epidemics cost the US economy $71-167 billion per year and that 250,000-500,000 ..
  13. Interrelationships among nutrients involved in one-carbon metabolism in Banglades
    MEGAN NINA HALL; Fiscal Year: 2011
    ..countries are chronically exposed to As-contaminated drinking water at concentrations far exceeding the World Health Organization standard of 10 5g/L...
  14. The Role of Alcohol in HIV Therapy Hepatotoxicity
    Craig J McClain; Fiscal Year: 2012
    ..Hepatotoxicity due to HAART is also common, and up to 30% of patients on HAART experience World Health Organization grade 3 liver enzyme elevations...
  15. Severe H1N1 Influenza Infection During Pregnancy: Pathophysiologic Mechanisms
    Mark Phillippe; Fiscal Year: 2010
    ..other countries in the Americas, Europe, Asia, the Middle East, and the Pacific basin, resulting in the World Health Organization (WHO) increasing its influenza threat rating to 6, signifying a global influenza pandemic...
  16. Improving Hmong Health through Community Based Participatory Research
    DIAN LORENE BAKER; Fiscal Year: 2013
    ..and healthcare navigators for Hmong community members with T2DM, (3) translate and evaluate the World Health Organization Quality of Life-BREF instrument for care management and biomedical research of T2DM among the Hmong ..
  17. The Role of Substrate Metabolism and Macrophage Activation in Obesity
    Amy Johnson; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The World Health Organization estimates 500 million adults and as many as 43 million children under the age of 5 are obese underscoring the fact that obesity and its related diseases, including ..
  18. Early social stress, novelty seeking, and impulsive behavior
    David M Lyons; Fiscal Year: 2013
    ..According to the World Health Organization, stress- related mental health disorders will be the second leading cause of all medical disabilities by ..
  19. Assessment of Bone Composition Through a Novel Liquid/Solid State MRI Method
    Ara Nazarian; Fiscal Year: 2013
    ..Based on the assumption that fragility fractures are caused by low bone mass, the World Health Organization (WHO) has identified individuals at risk for these fractures based on their areal bone mineral density ..
  20. Assessment of Bone Composition Through a Novel Liquid/Solid State MRI Method
    Ara Nazarian; Fiscal Year: 2011
    ..Based on the assumption that fragility fractures are caused by low bone mass, the World Health Organization WHO) has identified individuals at risk for these fractures based on their areal bone mineral density ..
  21. Arsenic co-carcinogenesis with UVR: nitrosation and oxidation of target proteins
    Ke Jian Liu; Fiscal Year: 2013
    ..to arsenic through drinking water at levels in excess of the Environmental Protection Agency and World Health Organization minimum contaminant level of 10 [unreadable]g/L is a national and international concern...
  22. Crystalline Endolysin Treatment for Tuberculosis in TB/HIV co-infected patients
    BHAMI C SHENOY; Fiscal Year: 2012
    ..The World Health Organization estimates that 2 million people worldwide die of TB each year...
  23. Novel Bacillus subtilis based spore vaccine to tuberculosis
    Subramanian Dhandayuthapani; Fiscal Year: 2013
    ..The World Health Organization estimates that at least 2 million people die every year because of TB, and that one-third of the living ..
  24. Tpl2 in Carcinogenesis-Related Inflammation
    KATHLEEN LEIGH DECICCO-SKINNER; Fiscal Year: 2011
    ..Additionally, the incidence of skin cancers has risen significantly since the 1970s, and the World Health Organization expects the skin-cancer epidemic to continue to accelerate...
  25. Structure and function of Helicobacter pylori VacA
    Timothy L Cover; Fiscal Year: 2013
    ..pylori has been classified as a type I carcinogen by the World Health Organization. One of the major secreted proteins of H. pylori is a toxin known as VacA...
  26. Role of Polo-like kinase (Plk-1) in Hepatitis B Virus-mediated Hepatocellular Car
    Ourania M Andrisani; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Chronic HBV infection leads to fatal liver cancer (1). The World Health Organization reports 400 million people are chronically infected with HBV, placing them at a greatly increased risk ..
  27. CHOLINERGIC MECHANISMS OF REM SLEEP GENERATION
    Helen A Baghdoyan; Fiscal Year: 2013
    ..Relevance to public health is evidenced by World Health Organization data reporting that 450 million people worldwide suffer from some form of mental or brain disorder, and ..
  28. Assessment of Dehydration in Children with Diarrhea in Resource-Limited Settings
    ADAM CARL LEVINE; Fiscal Year: 2013
    ..While the World Health Organization (WHO) recommends using a four-point clinical scale for determining the severity of dehydration in ..
  29. The role of polyphosphate and acidocalcisomes in Trypanosoma brucei
    Roberto Docampo; Fiscal Year: 2013
    ..According to the World Health Organization, over 60 million persons in sub-Saharan Africa are at risk of infection with an incidence of 300-500,000 ..
  30. Innate immunity predictors of HIV: the role of contraception, pregnancy and HSV-2
    Charles Morrison; Fiscal Year: 2013
    ..due to the conflicting epidemiologic study results and lack of sufficient mechanistic information, the World Health Organization held a technical consultation to evaluate the existing evidence on hormonal contraception and HIV ..
  31. Role of liver fluke granulin in cholangiocarcinogenesis
    Jason P Mulvenna; Fiscal Year: 2013
    ..As determined by the World Health Organization's International Agency for Research on Cancer, no stronger link exists between human malignancy and ..
  32. Toll-like Receptor 2, Vitamin D, and Extrapulmonary Tuberculosis
    CHRISTINA A FISKE; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Tuberculosis (TB) is a global health emergency. The World Health Organization estimated that approximately 9.3 million people worldwide were diagnosed with TB in 2007 and 2 million persons died...
  33. Planning a clinical trial of Flash-heated breast milk to decrease morbidity, impr
    Caroline J Chantry; Fiscal Year: 2010
    ..milk to decrease morbidity, improve growth, and reduce HIV transmission in HIV-exposed infants The World Health Organization recommends that HIV positive mothers in developing countries exclusively breastfeed for 6 months, and ..
  34. Prevalence of DSM-IV Disorders in an Multi-Center HIV+ Women's Cohort
    Judith A Cook; Fiscal Year: 2013
    ..study visit by WIHS interviewers who have been trained and certified in laptop CIDI administration by World Health Organization-sponsored trainers...
  35. Novel Spectinamide Antibiotics for the Treatment of MDR/XDR Tuberculosis
    Michelle M Butler; Fiscal Year: 2013
    ..TB is a lethal infectious disease, second only to HIV/AIDS as a cause of death. Estimates by the World Health Organization show one-third of the world population is infected with Mtb, the bacterium that causes TB;approximately ..
  36. Investigating SloR virulence gene metalloregulation in S. mutans.
    Grace A Spatafora; Fiscal Year: 2013
    ..formation continues to be a major problem in developed and developing nations which, according to the World Health Organization, impacts 60-90% of children world-wide (128)...
  37. Effect of a sanitation &nutrition intervention on HIV-exposed infant health
    JEAN HAWES HUMPHREY; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: Each year, 200,000 infants are infected with HIV during breastfeeding, so the World Health Organization recommends that HIV-positive mothers stop breastfeeding to reduce this transmission...
  38. IRS insecticides for malaria control and child neurodevelopment in South Africa
    Brenda Eskenazi; Fiscal Year: 2013
    ..For example, the Stockholm Convention on Persistent Organic Pollutants aims to ban DDT, while the World Health Organization and the U.S. Agency for International Development promote and/or fund IRS, including with DDT...
  39. 16th ISBRA Conference
    Edward P Riley; Fiscal Year: 2012
    ..Furthermore, according to the World Health Organization (WHO), alcohol consumption ranks as the world's 3rd risk factor for disease and disability, and in ..
  40. Nutrients involved 1-carbon metabolism and the methylation of arsenic and DNA
    MEGAN NINA HALL; Fiscal Year: 2013
    ..countries are chronically exposed to As- contaminated drinking water at concentrations far exceeding the World Health Organization standard of 10 [unreadable]g/L...
  41. Strain Specific Detection of Influenza at the Point-of-Care
    HYONGSOK TOM SOH; Fiscal Year: 2012
    ..PROJECT SUMMARY Influenza viruses cause significant morbidity and mortality worldwide;World Health Organization (WHO) estimates 250,000 ~ 500,000 yearly deaths...
  42. Investigating SloR virulence gene metalloregulation in S. mutans.
    Grace Spatafora; Fiscal Year: 2009
    ..formation continues to be a major problem in developed and developing nations which, according to the World Health Organization, impacts 60-90% of children world-wide (123)...
  43. 5-HT transporter function: Interaction of antidepressants and hormones
    Alan Frazer; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: By 2020, the World Health Organization has predicted that MDD will be the second leading cause of disease burden worldwide, with women in their ..
  44. Enhancement of Coronary Constriction by Volatile Organic Air Toxics
    Matthew J Campen; Fiscal Year: 2013
    ..Air pollution, especially particulate matter (PM), has a substantial impact on global health, with the World Health Organization estimating 800,000 annual excess cardiopulmonary deaths through mechanisms that are not entirely clear...
  45. Global Genomic and Proteomic Profiling of African Children with Typhoid Fever
    Stephen Obaro; Fiscal Year: 2013
    ..typhi), a human specific pathogen. The World Health Organization (WHO) recognizes typhoid fever as a global health problem, with an estimated 21 million cases and 200,..
  46. Pilot studies of the molecular epidemiology of drug-resistant malaria in Myanmar
    Christopher V Plowe; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The World Health Organization (WHO) is coordinating an aggressive effort to contain artemisinin resistant Plasmodium falciparum malaria in Southeast Asia before it spreads from its recent site of ..
  47. Investigation of synergy between Rifampin and SQ109, a new anti-TB drug candidate
    VENKATA REDDY; Fiscal Year: 2009
    ..tuberculosis. There are an estimated 400,000 new cases of MDR TB each year, and the World Health Organization (WHO) estimates there are 50 million individuals worldwide infected with a resistant strain of TB...
  48. Transcriptomics and Population Genetics of Mosquito Resistance to Pyrethroids
    Mariangela Bonizzoni; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The World Health Organization (WHO) estimates 500 million clinical cases of malaria and about one million deaths per year. The majority of malaria morbidity and mortality occurs in sub-Saharan Africa...
  49. Coregulatory Processes and Postpartum Depression in Mexican-Americans
    Linda J Luecken; Fiscal Year: 2013
    ..According to the World Health Organization (2007), depression is the leading cause of disability worldwide, and the fourth leading contributor to ..
  50. Neuroscience of Late-Life Depression, Social Perception, and Emotional Awareness
    Sergio Paradiso; Fiscal Year: 2012
    ..The World Health Organization has projected that depression will soon be second only to heart disease as a cause of disability...
  51. Malaria treatment outcomes and pharmacokinetics in HIV-infected pregnant women
    MYAING MYAING NYUNT; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Artemether-lumefantrine is the leading drug recommended by the World Health Organization (WHO) for the treatment of uncomplicated malaria caused by Plasmodium falciparum...
  52. Maternal and Child Health Benefits from Reducing Household Air Pollution
    Patricia L Hibberd; Fiscal Year: 2013
    ..traditional cook stoves and solid fuels that generate high levels of household pollutants, far exceeding World Health Organization (WHO) indoor air quality guidelines...
  53. Tsetse Transmitted African Trypanosomiasis
    Serap Aksoy; Fiscal Year: 2013
    ..Yale University scientists will continue to work with the Kenya Trypanosomiasis Research Center (TRC), World Health Organization designated Center of Excellence, to coordinate the capacity strengthening activities for HAT...
  54. A Novel Neuroprotective Protein, Thorase
    Valina L Dawson; Fiscal Year: 2012
    ..are the leading cause of death, disability and loss of quality of life worldwide according to the World Health Organization. The incidence of these disorders ranges from stroke, epilepsy and Alzheimer's, which affect ..
  55. Development of a Manufacturing Process for a Novel TB Vaccine
    VIJAY YABANNAVAR; Fiscal Year: 2013
    ..widespread use of the only available licensed TB vaccine, Bacille Calmette-Guerin (BCG), under the World Health Organization (WHO) expanded program on immunization (EPI)...
  56. FT-IR Microscopy of Mineral Structure
    Adele L Boskey; Fiscal Year: 2013
    ..The NIH Consensus conference and the World Health Organization defined osteoporosis as "...compromised bone strength predisposing to an increased risk of fracture"...
  57. Community-based interventions to reduce mortality from neonatal infection
    Waldemar A Carlo; Fiscal Year: 2012
    ..Current World Health Organization (WHO) recommendations for the treatment of infants with suspected serious bacterial infection include ..
  58. Giardia drug targets: Structure, function and inhibitors
    Osnat Herzberg; Fiscal Year: 2010
    ..countries and meager efforts expended to identify new therapies, giardiasis has been designated a World Health Organization neglected disease...
  59. Point-of-Care Diagnostic Assay for Direct Detection of Pathogenic Leptospira
    Jeffrey Smith; Fiscal Year: 2010
    ..Most often this occurs by contact with contaminated bodies of water or soil. The World Health Organization lists the groups of people at risk of the infection ranging from cattle and pig farmers to veterinarians,..
  60. Identifying neurons and circuits critical for epileptogenesis
    Istvan Mody; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): According to the World Health Organization (WHO), epilepsies affect over 50 million people worldwide...
  61. Cinema Smoking and Youth Smoking in Latin America
    James Thrasher; Fiscal Year: 2013
    ..to movie smoking have been promulgated as part of the implementation guidelines for Article 13 of the World Health Organization's Framework Convention on Tobacco Control...
  62. Effects of Tobacco Exposure on Immune Responses
    Kari C Nadeau; Fiscal Year: 2013
    ..provided by applicant): An estimated 1 billion people currently smoke tobacco, world-wide, and the World Health Organization forecasts cigarettes will kill nearly 9 million people per year globally by the year 2030...
  63. Investigations of the role of house flies as vectors for bacterial pathogens
    Dana Nayduch; Fiscal Year: 2009
    ..The World Health Organization (WHO) has reported that diarrheal illnesses are one of the top causes of morbidity and mortality in ..
  64. INTERNET CONNECTION FOR 5 TUBERCULOSIS INSTITUTIONS
    Paula Miller; Fiscal Year: 2002
    ..The World Health Organization has identified the lack of training and updated knowledge of TB among Primary Health Care staff as one ..
  65. Advancing lead dipiperidine compound into preclinical development
    Marina Protopopova; Fiscal Year: 2009
    ..The current therapeutic regimen for TB recommended by the World Health Organization (WHO) requires the administration of four drugs for six months, which has a dismal compliance rate (30-..
  66. Phase 2 Pharmacodynamic Study of High-dose Levofloxacin in MDR-TB Treatment
    C Robert Horsburgh; Fiscal Year: 2010
    ..NIAID, the World Health Organization, and the STOP-TB Partnership have identified research on and treatment of MDR-TB and XDR-TB as urgent ..
  67. ANALYSIS OF THE TRYPANOSOMA BRUCEI GENOME USING TILING ARRAYS
    Christian Tschudi; Fiscal Year: 2009
    ..The World Health Organization conservatively estimates that the disease burden of human African trypanosomiasis or sleeping sickness ..
  68. CARCINOGENICITY OF 2-NITROPROPANE--A PROBABLE MECHANISM
    Emerich Fiala; Fiscal Year: 2000
    ..The World Health Organization estimates that approximately 4000 U.S...
  69. A Bi-Institutional Pilot Study of Vaccinations for Patients with Low Grade Glioma
    Edward G Shaw; Fiscal Year: 2010
    ..of poly-ICLC) that is designed to efficiently induce anti-tumor T-cell responses in adults with either World Health Organization (WHO) grade II astrocytoma or oligoastrocytoma with poor prognostic factors...
  70. Social Cognition and Functioning in Bipolar Disorder
    Michael F Green; Fiscal Year: 2010
    ..BPD is highly disabling;based on recent data from the World Health Organization, BPD is the 7th leading cause of years lost to disability for men, and the 8th leading cause for women...
  71. PREPARATION FOR AIDS/HIV VACCINE EVALUATIONS
    Susan Allen; Fiscal Year: 1993
    ..Existing research projects coordinated by the National AIDS Control Program (NACP) and funded by the World Health Organization (WHO), the US National Institutes of Health (NIH), the Belgian government, and the European Economic ..
  72. TRYPANASOMA CRUZI GENOME-SBRI
    Kenneth Stuart; Fiscal Year: 2004
    ..The project will also be conducted in coordination with the genome networks that were organized by the World Health Organization to sequence the genomes of these three pathogens...
  73. Brugia Malayi Genome Project
    Elodie Ghedin; Fiscal Year: 2002
    ..Presently, the World Health Organization estimates over 140 million cases with over a billion people at risk for infection...
  74. Effect of Cdk inhibitor on HIV-1 replication
    Fatah Kashanchi; Fiscal Year: 2007
    ..human immunodeficiency virus (HIV), and nearly 16,000 new infections occur worldwide each day based on World Health Organization estimates...
  75. MASSAGE THERAPY FOR EXPERIMENTAL LYMPHEDEMA
    Marlys Witte; Fiscal Year: 2002
    ..consensus-recommended optimal treatment for lymphedema(LE) of the arms and legs, which according to the World Health Organization affects hundreds of millions worldwide...
  76. CrPV IRES function and animal virus replication in yeast
    SUNNIE THOMPSON; Fiscal Year: 2006
    ..the most well known enterovirus in the picornavirus family, is soon to be declared eradicated by the World Health Organization, there are 66 other distinct human enteroviruses that are still infecting populations worldwide...
  77. TRAJECTORY OF RECOVERY OF LIFE-SPACE MOBILITY AFTER HOSPITALIZATION
    Cynthia Brown; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): According to the World Health Organization (WHO), disability is a reduction in function in one of three domains that include body function or structure, activity and participation...