Genomes and Genes
forms and records control
Summary: A management function in which standards and guidelines are developed for the developing, maintaining, and handling of forms and records.
Publications294 found, 100 shown here
- Keeping internal chart reviews from being used against you: 11 useful strategiesDavid M Glaser
Fredrikson and Byron, 200 South Sixth Street, Minneapolis, MN, USA
J Med Pract Manage 20:32-5. 2004..This article provides some guidance to help practitioners realize the fuller value of chart reviews in terms of over- and under-coding, adequacy of documentation, and attorney-client privilege...
- Assessing validity of ICD-9-CM and ICD-10 administrative data in recording clinical conditions in a unique dually coded databaseHude Quan
Department of Community Health Sciences and Centre for Health and Policy Studies, University of Calgary, 3330 Hospital Dr NW, Calgary, AB T2N4N1, Canada
Health Serv Res 43:1424-41. 2008....
- Handheld computers. A feasible alternative to paper forms for field data collectionLinda A Fletcher
Alcohol Epidemiology Program, University of Minnesota School of Public Health, USA
Eval Rev 27:165-78. 2003..Paper forms handled written comments better. Handheld computers are a feasible alternative to paper forms for field data collection...
- Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care databaseMartin C Gulliford
Division of Health and Social Care Research, King s College London, London, UK
PLoS ONE 4:e7168. 2009..This study aimed to evaluate the relevance of different codes for the identification of acute stroke in a primary care database, and to evaluate trends in the use of different codes over time...
- Validation of diagnostic codes within medical services claimsMachelle Wilchesky
Department of Epidemiology and Biostatistics, McGill University, Morrice House, 1140 Pine Avenue West, Montreal, QCH3A 1A3, Canada
J Clin Epidemiol 57:131-41. 2004....
- Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes researchDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Canada
Med Care 43:182-8. 2005..Despite the potential usefulness of administrative databases for evaluating outcomes, coding of heart failure and associated comorbidities have not been definitively compared with clinical data...
- Automating the assignment of diagnosis codes to patient encounters using example-based and machine learning techniquesSerguei V S Pakhomov
Division of Biomedical Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
J Am Med Inform Assoc 13:516-25. 2006..Human classification of diagnoses is a labor intensive process that consumes significant resources. Most medical practices use specially trained medical coders to categorize diagnoses for billing and research purposes...
- Identifying patients with a cancer diagnosis using general practice medical records and Cancer Registry dataShane W Pascoe
Centre for Primary Health Care and Equity, University of New South Wales, Sydney 2052, Australia
Fam Pract 25:215-20. 2008..ii) To describe the effectiveness of search strategies to identify all patients in primary care with a cancer diagnosis compared with a diagnosis identified by a Cancer Registry...
- A systematic review of discharge coding accuracyS E Campbell
University of Aberdeen, Woodend Hospital
J Public Health Med 23:205-11. 2001..However, policy-makers, planners and researchers need to recognize and account for the degree of inaccuracy in routine hospital information statistics. Further research is needed into methods of improving and maintaining coding accuracy...
- Validity of procedure codes in International Classification of Diseases, 9th revision, clinical modification administrative dataHude Quan
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
Med Care 42:801-9. 2004..However, little is known about the validity of administrative coding of procedure data. We conducted a detailed chart review to evaluate the accuracy and completeness of information on procedures in administrative data...
- Assessing accuracy of diagnosis-type indicators for flagging complications in administrative dataHude Quan
Quality Improvement and Health Information, Calgary Health Region, 1403 29th Street NW, Calgary, Alberta, Canada T2N 2T9
J Clin Epidemiol 57:366-72. 2004..Given that the validity of diagnosis-type indicators is unknown, we conducted a detailed chart review to evaluate the accuracy of diagnosis-type indicators for flagging complications...
- Validity of information on comorbidity derived rom ICD-9-CCM administrative dataHude Quan
Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
Med Care 40:675-85. 2002..The predictive ability of comorbidity information in the two data sets for predicting in-hospital mortality was also compared...
- Benchmarking variation in coding accuracy across the United StatesDaniel P Lorence
College of Human Development, Department of Health Policy and Administration, School of Information Sciences and Technology, Pennsylvania State University, University Park, PA, USA
J Health Care Finance 29:29-42. 2003..As the United States moves toward an evidence-based medicine environment, the use of current patient data classification methods may be of limited value without increased attention to coding practices...
- Identifying priorities in methodological research using ICD-9-CM and ICD-10 administrative data: report from an international consortiumCarolyn De Coster
Department of Community Health Sciences, University of Calgary, Calgary, Canada
BMC Health Serv Res 6:77. 2006..This paper presents a list of high-priority methodological areas for researchers using health administrative data...
- An audit of operative notes: facts and ways to improveLiviu P Lefter
Department of Surgery, Royal Hobart Hospital, Hobart, Tasmania, Australia
ANZ J Surg 78:800-2. 2008..Therefore, we audited the surgical notes in a teaching hospital surgical department...
- Standards in medical record keepingRobin Mann
Health Informatics Unit, Royal College of Physicians, London
Clin Med 3:329-32. 2003..The first draft of these standards has been released for consultation purposes. This article is the first of a series that will describe the standards, and the evidence behind them...
- The time needed for clinical documentation versus direct patient care. A work-sampling analysis of physicians' activitiesE Ammenwerth
Institute for Health Information Systems, UMIT University for Health Sciences, Medical Informatics, and Technology Tyrol, Eduard Wallnöfer Zentrum 1, 6060 Hall in Tyrol, Austria
Methods Inf Med 48:84-91. 2009..We analyzed the time needed for clinical and administrative documentation, and compared it to other tasks, such as direct patient care...
- Accuracy of injury coding under ICD-9 for New Zealand public hospital dischargesJ Langley
Injury Prevention Research Unit, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Inj Prev 12:58-61. 2006..To determine the level of accuracy in coding for injury principal diagnosis and the first external cause code for public hospital discharges in New Zealand and determine how these levels vary by hospital size...
- Development and testing of a hierarchical method to code the reason for admission to intensive care units: the ICNARC Coding Method. Intensive Care National Audit & Research CentreJ D Young
Nuffield Department of Anaesthetics, Radcliffe Infirmary, Oxford, UK
Br J Anaesth 87:543-8. 2001..1%) in the primary reason for admission. Five conditions account for 19.4% of all primary reasons for admission. This is the first method to be developed empirically for coding the reason for intensive care admission...
- The quality of record keeping in primary care: a comparison of computerised, paper and hybrid systemsWilliam T Hamilton
Division of Primary Health Care, University of Bristol
Br J Gen Pract 53:929-33; discussion 933. 2003..Computerised record keeping in primary care is increasing. However, no study has systematically examined the completeness of computer records in practices using different forms of record keeping...
- Variation in coding influence across the USA. Risk and reward in reimbursement optimizationDaniel P Lorence
Department of Health Policy and Administration, Pennsylvania State University, State College, Pennsylvania, USA
J Manag Med 16:422-35. 2002..Implications for reimbursement programs and evidence-based health care are discussed...
- Reliability of diagnoses coding with ICD-10Jurgen Stausberg
Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg Essen, Hufelandstr 55, D 45122 Essen, Germany
Int J Med Inform 77:50-7. 2008..Reliability of diagnoses coding is essential for the use of routine data in a national health care system. The present investigation compares reliability of diagnoses coding with ICD-10 between three groups of coding subjects...
- Manager's reports of variation in coding accuracy across U.S. oncology centersDaniel P Lorence
Dept of Health Policy Administration, Pennsylvania State University, University Park, PA 16801, USA
J Oncol Manag 11:20-6. 2002..Regional and practice setting variation in reported coding error ranged widely, occurring across organizations as well as area locations. Related impact on comparative data-driven management assessment is discussed...
- Coordinating SNOMED-CT and ICD-10Sue Bowman
J AHIMA 76:60-1. 2005
- Evaluation and management codes: from current procedural terminology through relative update commission to Center for Medicare and Medicaid ServicesTodd Dorman
The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 34:S71-7. 2006..In addition, a better understanding of documentation requirements and the audit process will facilitate improved compliance and minimize liability...
- An Ontology driven collaborative development for biomedical terminologies: from the French CCAM to the Australian ICHI coding systemJean M Rodrigues
University of Saint Etienne, France
Stud Health Technol Inform 124:863-8. 2006..The initial results are presented and discussed in terms of feasibility and quality assurance for sharing and maintaining consistent medical knowledge and allowing diversity in linguistic expressiveness of end users...
- Have DRG-based prospective payment systems influenced the number of secondary diagnoses in health care administrative data?Lisbeth Serdén
Centre for Patient Classification Systems, Centre for Epidemiology, National Board of Health and Welfare, SE 10630 Stockholm, Sweden
Health Policy 65:101-7. 2003..Other reasons may also have contributed to the increase. It was found that the changes in the speciality mix, during the study period, have impact on the increase of secondary diagnoses...
- Organisational factors affecting the quality of hospital clinical codingSuong Santos
The Alfred Hospital, Melbourne, Vic, Australia
HIM J 37:25-37. 2008....
- Medicare upcoding and hospital ownershipElaine Silverman
Dartmouth Medical School, Hanover, NH 03755, USA
J Health Econ 23:369-89. 2004..Upcoding appears to reflect both risk-taking by administrators and a closer alignment between the goals of the administration and the behavior of the clinical staff...
- Data management in practice-based researchJoanne Nyiendo
Western States Chiropractic College, Division of Research, Center for Outcomes Studies, Portland, Ore 97230, USA
J Manipulative Physiol Ther 25:49-57. 2002..This article explores data management issues encountered in the design, conduct, and analysis of a research project involving 74 community-based sites and a central data management system...
- Principles of good medical record documentationB J Murphy
Illinois State Medical Insurance Services, Inc, 20 N Michigan Avenue, Suite 700, Chicago, IL 60602, USA
J Med Pract Manage 16:258-60. 2001..This article will help show why good documentation is so important not only for good medical care, but if needed, as a defense tool if faced with a medical malpractice claim...
- Using administrative data to study persons with disabilitiesLisa I Iezzoni
Harvard University, USA
Milbank Q 80:347-79. 2002..Linking administrative data to survey or other data sources enhances the utility of administrative data for disability studies...
- Data collection in a multisite project: TeleformJ Michael Hardin
Department of Information Systems, Statistics, and Management, Culverhouse College of Commerce, University of Alabama, Tuscaloosa 35487, USA
Public Health Nurs 22:366-70. 2005..Our research team chose Teleform for data entry and collection for the Smoking Cessation or Reduction in Pregnancy Trial study. This article presents our experience with this new technology...
- Role of a medical staff coding committee in documentation, coding, and billing complianceNelson P Gruber
University of Texas Harris County Psychiatric Center, 2D 08, 2800 South MacGregor Way, Houston, TX 77021, USA
Psychiatr Serv 53:1629-31. 2002..The committee has evolved into a highly effective and important component of the institution's overall compliance program. The authors discuss the origins, development, and accomplishments of the medical staff coding committee...
- Coding and billing for gastrointestinal endoscopyPatricia L Stout
Professional Coding Services, 2001 Laurel Ave, Newland Professional Bldg, Suite 602, Knoxville, TN 37916, USA
Gastrointest Endosc Clin N Am 12:335-49. 2002..This is a significant indicator of a physicians' intent to have a compliant and financially successful practice...
- Practice brief. Maintaining a legally sound health recordMitchelle Dougherty
J AHIMA 73:64A-64G. 2002
- Coding errors and the trauma patient--is nursing case management the solution?Kate Curtis
St George Hospital
Aust Health Rev 25:73-80. 2002..The validity of coding is dependent on legible, comprehensive and complete documentation and is improved dramatically by using nursing case manager patient progress summaries...
- Coding & billing. Will codes turn 10?Richard Haugh
Hosp Health Netw 79:18, 20, 4. 2005..All of health care continues to hold its collective breath waiting for the Health and Human Services Department to give its final blessing to a new and improved coding system, ICD-10. But that wait could go on for a few more years...
- The trouble with DRGs, part 1Robert J Mahoney
Division of Hospital Medicine, Washington University School of Medicine, USA
J AHIMA 76:66-8. 2005
- Taming variability in free text: application to health surveillanceAlan R Shapiro
Department of Medicine, New York University School of Medicine, 5 Pheasant Run, Pleasantville, NY 10570, USA
MMWR Morb Mortal Wkly Rep 53:95-100. 2004..Failure to detect these variations results in missed cases, and traditional methods for capturing these variations require ongoing, labor-intensive maintenance...
- Better documentation through standardized forms: what progress have we made since the 1800s?Linda Cox
Nova Southeastern University Ostheopathic School of Medicine, Allergy Asthma Center, Fort Lauderdale, Florida 33334, USA
Allergy Asthma Proc 25:407-22. 2004....
- An interdisciplinary documentation performance improvement projectNancy Davidson
Nephrology Renal Transplant Unit, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Nurses Staff Dev 20:236-41. 2004..This article identifies the process used to revise and implement an interdisciplinary documentation system. Project implementation and outcomes as well as recommendations and future initiatives are included...
- Coding: what's new?Dorothy L Pennachio
Med Econ 81:25-6, 28. 2004
- Falls documentation in nursing homes: agreement between the minimum data set and chart abstractions of medical and nursing documentationElizabeth E Hill-Westmoreland
Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
J Am Geriatr Soc 53:268-73. 2005..To assess the agreement between falls as recorded in the Minimum Data Set (MDS) and fall events abstracted from chart documentation of elderly nursing home (NH) residents...
- 10 tips for avoiding APC trapsJulie A Micheletti
HSS, Inc, Hamden, Connecticut, USA
Healthc Financ Manage 56:64-8. 2002..Transitional pass-through items should be audited routinely; associated coding should be kept current. Consideration should be given to meeting medical necessity requirements, particularly for mental health services...
- Overview of inpatient codingSherri Alexander
Outcomes Research Group, US Medical Division, Eli Lilly and Company, Indianapolis, IN 46285, USA
Am J Health Syst Pharm 60:S11-4. 2003..Appropriate documentation is key for quality and continuity of care and compensation for resources utilized. In the future the ICD-9-CM will be replaced by the 10th revision, ICD-10, which is already in use in many countries in Europe...
- A new era of documentation in psychiatry: advice on psychotherapy, progress notesPeter B Gillman
Behav Healthc Tomorrow 13:48-50. 2004
- Documentation: a guide for case managersJackie Birmingham
Clinical Design, Curaspan, Inc
Lippincotts Case Manag 9:104-5. 2004
- Assessing managed care market variation in reports of coding accuracyDaniel P Lorence
Health Policy and Administration, Pennsylvania State University, University Park, PA, USA
Manag Care Q 10:15-25. 2002..Implications for managers and policymakers, related to comparative managed care data benchmarks, are reviewed...
- International refined DRGs globalize codingRobert L Mullin
J AHIMA 74:70-2, 74. 2003
- The power of persuasion. Proven strategies inspire physicians to improve documentationRuthann Russo
HP3 Inc, Bethlehem, PA, USA
J AHIMA 74:29-33; quiz 35-6. 2003
- [Evaluation of the quality of filling out medical records in a hypertension consultation]A Tache
, , Paris
Arch Mal Coeur Vaiss 90:1189-93. 1997..In the computerized records, only physical activity completion rate decreased. In conclusion, the computer may help to increase the quality of the medical records as reflected by the completion rate of items related to hypertension care...
- An update on the E/M codes and documentation guidelinesKent J Moore
Fam Pract Manag 10:14. 2003
- Improving documentation of patient acuity level using a progress note templateEric L Grogan
Department of Surgery, Vanderbilt University, Nashville, TN 37232 9485, USA
J Am Coll Surg 199:468-75. 2004..We hypothesized that a progress note template containing comorbidities and complications would improve documentation and teach residents to correctly document comorbidities and complications...
- Sepsis, related terms cause confusion for codersSue Prophet-Bowman
J AHIMA 74:81-3. 2003
- The integrated summary: a documentation tool to improve patient careMichael A Stelman
Fam Pract Manag 10:33-9. 2003
- More than code revisions in the 2004 changes to ICD-9-CMKathy Giannangelo
J AHIMA 75:94-6. 2004
- Major changes for heart failure codes in 2003Patricia E Casey
J AHIMA 74:75-8; quiz 79-80. 2003
- Understanding pelvic adhesions. How to get up to date with procedures, codesNikos F Vlahos
John Hopkins University School of Medicine, USA
J AHIMA 74:74-7; quiz 79-80. 2003
- Completeness of data on daily patient encounter forms at Mankweng HospitalD M Sekokotla
Burden of Disease Research Unit, Medical Research Council, Pretoria
S Afr Med J 92:954-6. 2002
- Where to find answers to your coding questionsKathy Brouch
J AHIMA 74:84-6; quiz 87-8. 2003
- Making your encounter form work for youCrystal S Reeves
Coker Group, 11660 Alpharetta Highway, Suite 710, Roswell, Georgia 30076, USA
J Med Pract Manage 19:150-3. 2003..A well-designed encounter form is one key to enhance the process. This article provides some practical guidelines for making the encounter form more effective...
- Practice brief. Managing an effective query processSue Bowman
J AHIMA 79:83-8. 2008
- Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal FailureSushrut S Waikar
Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Am Soc Nephrol 17:1688-94. 2006..The excellent performance characteristics of ICD-9-CM codes for ARF-D suggest that administrative data sets may be particularly well suited for research endeavors that involve patients with ARF-D...
- National provider identifier update: The impact on imaging centersPatricia Kroken
Radiology Consulting Group, Albuquerque, NM, USA
Radiol Manage 28:46-7. 2006
- Piecing together the PHRKevin Heubusch
J AHIMA 78:28-32. 2007
- The challenge of mapping between two medical coding systemsBarbara E Wojcik
Center for Army Medical Department Strategic Studies, U S Army Medical Department Center and School, Fort Sam Houston, TX 78234 5047, USA
Mil Med 171:1128-36. 2006..Our study objective was to determine whether reliable conversion between PC codes and International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis codes is possible...
- Medical record keeping and information retrieval in developing countries: surgeons' perspectiveEmmanuel A Ameh
Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
Trop Doct 32:232-4. 2002
- Effective medical documentationRebecca W West
Piedmont Liability Trust, Charlottesville, Virginia 22903, USA
J Am Coll Radiol 2:541-2. 2005
- Screening for painDeborah Johann
Suburban Hospital, Bethesda, MD, USA
Nurs Manage 38:42-4, 46-7. 2007
- Completeness of medical records in emergency trauma care and an IT-based strategy for improvementM de Mul
Erasmus MC, University Medical Centre Rotterdam, Institute of Health Policy and Management, Rotterdam, The Netherlands
Med Inform Internet Med 32:157-67. 2007..One solution we propose is to restructure the recording process by introducing a clerk. This clerk could also be a nurse or physician who is temporarily released from direct patient care...
- Best practices for improving revenue capture through documentationErin Richter
The Advisory Board Company, Washington, DC, USA
Healthc Financ Manage 61:44-7. 2007....
- The assessment and documentation of language and communication needs in healthcare systems: current practices and future directions for coordinating safe, patient-centered careRegina E Nailon
Alegent Health, Center for Nursing Excellence, 11128 John Galt Boulevard, Suite 410, Omaha, NE 68137 2321, USA
Nurs Outlook 55:311-7. 2007..Nurses play a key role in developing and evaluating information systems with which accurate and reliable data can be collected, documented, retrieved, and utilized...
- Handheld computers for self-administered sensitive data collection: a comparative study in PeruAntonio Bernabe-Ortiz
School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru
BMC Med Inform Decis Mak 8:11. 2008..The goal of this study is to evaluate the quality of sexual behavior data collected with handheld computers in comparison with paper-based questionnaires...
- Leading clinical documentation improvement. Three successful HIM-led programsChris Dimick
J AHIMA 79:40-2, 44; quiz 47-8. 2008..Clinical documentation improvement programs are increasingly common, but who leads them varies. Here's a look at three successful programs led by HIM departments...
- Who signs what, and how often? What you need to know about new signature requirementsG Christopher Kelly
EMS Mag 37:50. 2008
- Managing the life cycle of electronic clinical documentsThomas H Payne
UW Medicine Information Technology Services, University of Washington, 9725 3rd Avenue N E Room 513, Box 359104, Seattle, Washington 98115 2024, USA
J Am Med Inform Assoc 13:438-45. 2006..To develop a model of the life cycle of clinical documents from inception to use in a person's medical record, including workflow requirements from clinical practice, local policy, and regulation...
- To have and to hold--but for how long? Guidelines for records retentionLisa H Schneck
MGMA Connex 2:32-3. 2002
- 11 tips for more productive billingMaria V Ciletti
Fam Pract Manag 9:16-7. 2002
- How HIM can ease the pain of medical errorsValerie J M Watzlaf
Department of Health Information Management, School of Health and Rehabilitation Sciences, University of Pittsburgh, USA
J AHIMA 73:37-44; quiz 45-6. 2002
- The codes to watch: identifying the DRGs most prone to payment errorKimberly Hrehor
Texas Medical Foundation, Austin, TX, USA
J AHIMA 76:36-40. 2005
- Quality assurance in radiotherapy. How to improve the effectiveness and completeness of an electronic patient's chartMaurizio Portaluri
Dipartimento di Radioterapia, AUSL BR1, Ospedale Perrino, Brindisi, Italy
Ann Ist Super Sanita 41:493-9. 2005..The average global score increased from 0.4 to 0.7: in A (lowest complexity) category from 0.37 to 0.64, in B category from 0.4 to 0.89, in C category from 0.48 to 0.61...
- The documentation dilemma. Nurses poised to address paperwork burdenSusan Trossman
Tar Heel Nurse 64:10-1. 2002
- [Comparison of MDS-AC registration and conventional medical records in Iceland and other Nordic countries. A part of a Nordic study]Olafur Samuelsson
Department of Geriatrics, Iceland University Hospital, Landakoti, 101 Reykjavik
Laeknabladid 91:335-41. 2005..The object of this study was to compare the MDS-AC registration with the traditional nurses and doctors records for chosen variables important to older patient care in Iceland and other Nordic countries...
- How does your coding measure up? Analyzing performance data gives HIM a boost in managing revenueKate Price
HSS, Inc, USA
J AHIMA 76:26-31; quiz 33-4. 2005
- In so many words, lab reports on the mendMariann Stephens
CAP Today 19:5. 2005
- The tyranny of the diagnosis codeVergil N Slee
Health Commons Institute, USA
N C Med J 66:331-7. 2005..But no practical method for their input and management has been offered This paper proposes a way to provide easy input of diagnosis entities, and their permanent coding as a workable solution to the problem...
- Final HIPAA privacy rules: "How do we get started?"B M Broccolo
Gardner, Carton and Douglas, Chicago, Illinois, USA
J Health Care Finance 27:7-23. 2001....
- Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extractYi Liu
Institute of Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu, P R China The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu, P R China
Toxicol Appl Pharmacol 282:9-19. 2015..These data define a link between inflammation and EMT, processes involved in the malignant transformation of cells caused by CSE. This link, mediated through lncRNAs, establishes a mechanism for CSE-induced lung carcinogenesis. ..
- Cloning of complimentary deoxyribonucleic acid encoding follicle-stimulating hormone and luteinizing hormone beta subunit precursor molecules in Reeves's turtle (Geoclemys reevesii) and Japanese grass lizard (Takydromus tachydromoides)Youichi Aizawa
Department of Biology, School of Education, Waseda University, 1 6 1 Nishi Waseda, Shinjuku ku, 169 8050 Tokyo, Japan
Gen Comp Endocrinol 132:465-73. 2003....
- DNA sequence of a gene cluster coding for subunits of the F0 membrane sector of ATP synthase in Rhodospirillum rubrum. Support for modular evolution of the F1 and F0 sectorsG Falk
Department of Biochemistry, Arrhenius Laboratory, University of Stockholm, Sweden
Biochem J 254:109-22. 1988..rubrum. The finding that genes for the F0 and F1 sectors of the enzyme are in separate clusters supports the view that these represent evolutionary modules...
- Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineeringKi Sung Lee
School of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Korea
Biotechnol Bioeng 108:621-31. 2011..cerevisiae. In addition, these results will be industrially useful in the biofuels area as galactose is one of the abundant sugars in marine plant biomass such as red seaweed as well as cheese whey and molasses...
- Immunogenicity of an aphthovirus chimera of the glycoprotein of vesicular stomatitis virusP R Grigera
Centro de Virologia Animal CEVAN CONICET, Buenos Aires, Argentina
J Virol 70:8492-501. 1996..These results suggest that the chimeric VSV-G/FMDV-ASA proteins mimic the capacity of FMDV to raise and react with neutralizing antibodies to a restricted number of ASA conformations present on the surface of native FMDV particles...
- Intergenic, gene terminal, and intragenic CpG islands in the human genomeYulia A Medvedeva
Research Institute for Genetics and Selection of Industrial Microorganisms, Genetika, 1st Dorozhny proezd, 1, Moscow, 117545, Russia
BMC Genomics 11:48. 2010..The human genome contains many such CpG islands; however, until now their properties were not systematically studied...
- Specific secondary structures in the capsid-coding region of giardiavirus transcript are required for its translation in Giardia lambliaS Garlapati
Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143 0446, USA
J Mol Biol 308:623-38. 2001..lamblia...
- [What's new in dermatological research?]P Humbert
Service de Dermatologie, CHU Saint Jacques, Universite de Franche Comte, INSERM U645, Besancon, France
Ann Dermatol Venereol 135:S326-34. 2008..Thus, many fields of dermatology were the object of research which opens new prospects for diagnosis and treatment...
- [Physiological characteristics and cardiac electrophysiology manifested in Minnesota coding of the "desert people" in Taklimakan Desert: study of 224 cases]Yusupjan Abdulla
Department of Cardiology, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China
Zhonghua Yi Xue Za Zhi 86:3277-9. 2006..To study the physiological characteristics and cardiac electrophysiology of the "desert people" in Taklimakan Desert, an isolated population of Uygurs...
- Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortusMaria de Lourdes Mottier
Institute of Parasitology, McGill University, Sainte Anne de Bellevue, Quebec, Canada
Pharmacogenet Genomics 18:129-40. 2008..contortus with known treatment history and status for susceptibility or resistance to macrocyclic lactone (ML) or benzimidazole anthelmintics...
- [Analysis, identification and correction of some errors of model refseqs appeared in NCBI Human Gene Database by in silico cloning and experimental verification of novel human genes]De Li Zhang
Key Laboratory of the Ministry of Education on Bioinformatics, Institute of Bioinformatics, Department of Automation, School of Information Science and Technology, Tsinghua University, Beijing 100084, China
Yi Chuan Xue Bao 31:431-43. 2004..So human genome coding regions annotated by computer should be used with caution. (ABSTRACT TRUNCATED)..
- Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's diseaseP H Reddy
Genetics and Molecular Biology Branch, National Institutes of Health, Bethesda, MD 20892, USA
Philos Trans R Soc Lond B Biol Sci 354:1035-45. 1999..Thus, animals expressing the CAG repeat expansions appear to represent clinically analogous models for HD pathogenesis, and may also provide insights into the underlying pathophysiological mechanisms of other triplet repeat disorders...
- Phylogenetics of asterids based on 3 coding and 3 non-coding chloroplast DNA markers and the utility of non-coding DNA at higher taxonomic levelsBirgitta Bremer
Department of Systematic Botany, Evolutionary Biology Centre, Norbyvagen 18D, SE 752 36 Uppsala, Sweden
Mol Phylogenet Evol 24:274-301. 2002..Several families of euasterids remain unclassified to order...
- Genetic variation and regulatory networks: Mechanisms and complexityDANA PE ER; Fiscal Year: 2009..These tools will be made publicly available, including a friendly graphical user interface and visualization. ..
- Personalized Clinical Diagnostics and Beyond: Integrated Ring Resonator ArraysRyan Bailey; Fiscal Year: 2009..This technology promises to broadly impact the landscape of the biomedical sciences, both meeting the clinical diagnostic challenges of today and pioneering the paradigm-shifting discoveries of tomorrow. ..
- High Throughput Genotyping and DNA Sequencing for Studying the Genetic ContributiSonia Dua; Fiscal Year: 2013..The contractor is responsible for providing staff with the credentials required by CLIA. ..
- Identification of Genetic and Epigenetic Alterations in SpondyloarthritisTibor T Glant; Fiscal Year: 2013....
- Genetics and Haloperidol ResponseRobert J Hitzemann; Fiscal Year: 2012....
- Genetic and physiological causes of inherited Vascular and Metabolic DiseasesArya Mani; Fiscal Year: 2013..The current study goals are investigating the effect of the mutation on metabolism of glucose and insulin secretion and function in patients with this mutation. ..
- Regulation of microRNA-375 by cyclic-AMP in pancreatic beta-cellsDAVID MATTHEW KELLER; Fiscal Year: 2010..This proposal will characterize a new target of cAMP signaling, microRNA-375, which has the potential to be used as a complementary therapy to enhance the efficacy of existing therapeutics that target the cAMP signaling pathway. ..
- Cellular Signaling in AlcoholismSubhash C Pandey; Fiscal Year: 2013....
- Novel genomic effects of Y-linked polymorphismsDaniel L Hartl; Fiscal Year: 2012..We predict that important phenotypic variation affecting human health and disease will ultimately be traced to variation in sequence repeats of noncoding DNA in the human Y chromosome. ..
- Characterization of epsilon-sarcoglycan interacting proteins in mouse brainYuqing Li; Fiscal Year: 2012..The results should significantly increase our understanding of the pathophysiology of M-D, which can ultimately aid the development of therapeutic treatments for M-D patients and other dystonia and myoclonus patients. ..
- Functional characters of non-coding RNAs in alcoholic liver injuryFanyin Meng; Fiscal Year: 2013..abstract_text> ..
- Non-coding RNA engineers antibody diversityUttiya Basu; Fiscal Year: 2011..Antibodies are polypeptide complexes produced from B-lymphocytes that are present in the bodily fluids of vertebrates, and are used by the immune system to identify and neutralize foreign antigens, such as bacteria and viruses. ..
- Interaction between RNA interference and RNA editing pathwaysKazuko Nishikura; Fiscal Year: 2013..Our research focuses also on apoptosis, which is highly relevant to many human diseases including cancer. ..
- MECHANISMS OF EUKARYOTIC TRANSCRIPTIONAL REGULATIONMichael R Green; Fiscal Year: 2013..A specific objective of the application is to study the mechanism by which tumor suppressor genes become transcriptionally silenced during cancer development. ..
- Development of a Porcine Model of AtherosclerosisChristopher Rogers; Fiscal Year: 2010..This animal model will provide academic and industrial research communities with an opportunity to better understand cardiovascular disease and its pathogenesis, and to develop and test new therapeutics and preventative strategies. ..
- Roles of RNA Polymerases IV and V in siRNA-mediated gene silencingCRAIG STUART PIKAARD; Fiscal Year: 2013..Our studies of RNA polymerases IV and V are significant with respect to all of these areas, especially the roles of intergenic noncoding RNAs and siRNAs in chromatin-mediated gene silencing. ..
- Structure and Function of the Hepatitis C Virus GenomePeter Sarnow; Fiscal Year: 2013..To do this, novel biochemical, structural and genetic approaches will be employed to study protein-HCV RNA interactions. ..
- Developing miRNA diagnostic methods and identifying tumor regulatory networksThomas Tuschl; Fiscal Year: 2010....
- Role of formyl peptide receptor variants in mucosal innate immune defenseHEINI MARITA MIETTINEN; Fiscal Year: 2010....
- ROLE OF MINERALOCORTICOIDS IN HYPERTENSIONCELSO ENRIQUE GOMEZ-SANCHEZ; Fiscal Year: 2012....
- Transgenerational effects of maternal high fat diet during pregnancy on breast caLeena A Hilakivi-Clarke; Fiscal Year: 2013....
- MicroRNAs in the Progression and Metastisis of Prostate CancerRajvir Dahiya; Fiscal Year: 2013..In the future, these results may provide better strategies for the management of prostate cancer. ..
- Genomic Enhancers at 8q24 and Prostate CancerGerhard A Coetzee; Fiscal Year: 2013....
- GLUTAMATE TRANSPORTERS IN THE CNSMICHAEL BYRNE ROBINSON; Fiscal Year: 2011..The name of the principal investigator/program director must be provided at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page i_ Description, ..
- Epigenetic Regulation of Serotonin:Relevance to HIV and Methamphetamine AbuseGREGORY MICHAEL MILLER; Fiscal Year: 2012....
- RNA polymerase II Elongation Complex: Structure and FunctionDaniel Reines; Fiscal Year: 2013..The parts of the transcription machinery studied here are involved in neurological, visual, and immunological diseases. ..
- Functional Studies of Variants of the Bipolar Risk Gene CACNA1C in Human NeuronsJEN PAN; Fiscal Year: 2013....
- Amoeboid Membrane Dynamics in Prostate CancerMichael R Freeman; Fiscal Year: 2013..DRF3 loss and the MAT may also be functionally important in other solid tumor systems. Consequently, these studies may provide information of more general significance to human cancer. ..
- The Role of the Nuclear Lamina in Chromatin Organization and Gene Expression in NMarcos Estecio; Fiscal Year: 2012....
- Telomere and its bio-regulators as predictors for clinical diabetes in womenSimin Liu; Fiscal Year: 2010....
- Genomics of RNA Editing: Identification and RegulationJin Billy Li; Fiscal Year: 2013....
- Structure-function analyses on novel processes of type II vestibular hair cellsJennifer S Stone; Fiscal Year: 2013..Studies of damaged vestibular organs will help uncover the relationship between normal and regenerated hair cells with processes and the potential of regenerated hair cells to restore function in balance and hearing disorders. ..
- Functional Analysis of the Embryonic Epigenome in a Non-rodent ModelMark E Westhusin; Fiscal Year: 2013....
- Growth Factor and Antiapoptotic Gene Delivery to Human IsletsRam I Mahato; Fiscal Year: 2012..This will decrease the number of islets required to achieve normoglycemia in type I diabetic patients. ..
- Epigenetic mechanisms of TDP43-mediated neurodegenerationAmit Berson; Fiscal Year: 2013....
- The Role of RNA Splicing Factors in Retinal DegenerationMichael Farkas; Fiscal Year: 2012..We believe that if we can identify the specific splicing alterations that cause RP in patients with these disorders, it is possible that similar therapeutic approaches could be developed for treating these diseases. ..
- ROLE OF ENHANCERS REGULATING RENIN GENE EXPRESSIONCURT DANIEL SIGMUND; Fiscal Year: 2013..These studies will link transcriptional signals regulating the renin gene with physiological endpoints controlling blood pressure and metabolism which may go awry in hypertension. I..
- Control of Cardiogenesis by microRNA EditingKazuko Nishikura; Fiscal Year: 2010....
- microRNAs as novel biomarkers for management of breast cancerLORENZO SEMPERE; Fiscal Year: 2012..Our results should provide a solid foundation to develop miRNA-based clinical assays to assist physicians in making crucial decisions with regards to treatment of patients. ..
- The Role of Long Non-coding RNAs in EMT and Cancer Stem CellsJason I Herschkowitz; Fiscal Year: 2013....
- Genomic approaches to inner ear hair cell regenerationMichael Lovett; Fiscal Year: 2010..The long-term goal of our research is to develop methods to regenerate and maintain inner ear hair cells by studying the regenerative process in birds and comparing it to mammalian hair cell growth. ..
- Defining the functions of uncharacterized genes in priority pathogensSean Crosson; Fiscal Year: 2013..S. Centers for Disease Control (CDC). Experiments proposed herein will define the biochemical function of uncharacterized genes implicated in regulation of B. abortus stress physiology and in the control of chronic brucellosis disease. ..
- MicroRNA-Based Therapeutics for Rare Cystic Kidney DiseasesPeter Igarashi; Fiscal Year: 2010..No specific treatment currently exists. This proposal will test the feasibility of treating these disorders using a new technology, microRNA-based therapeutics. ..
- Structural Studies of RNA Maturation and ProcessingChristopher D Lima; Fiscal Year: 2013..Pathways and enzymes that regulate the abundance, lifetime, and processing of RNA have been associated with human diseases that include neurodegenerative disorders, cancer, and inflammation. ..
- Translating human PPARy binding regions to gene regulation and metabolic diseaseRAYMOND EDWARD SOCCIO; Fiscal Year: 2013..Soccio from the mentored to the independent phase of this 5 year career development award. These studies of the human PPAR cistrome have potentially great translational relevance to the epidemics of diabetes and obesity. . ..
- Genome-wide Identification of Immediate Early Genes in InsectsAnandasankar Ray; Fiscal Year: 2012....
- Identification of Disease-Causing Mutations in SCID Using Exome-Wide SequencingJoseph L Roberts; Fiscal Year: 2010....
- Mutational Cloning in Familial Dementia and Alzheimers DiseaseWendy H Raskind; Fiscal Year: 2010..We will employ newly available powerful sequencing and bioinformatics techniques to detect causative mutations in families with apparent autosomal dominant dementia where the available affected persons are too few for linkage analyses. ..
- Molecular Analysis of Alcohol Effects on Human Oral Epithelium Cells'EpigenomeAlison Urvalek; Fiscal Year: 2013....
- Dysfunction of neurofilaments in disease: an iPS model of Giant Axonal NeuropathyBETHANY LESLIE JOHNSON-KERNER; Fiscal Year: 2012..This model will provide a platform to test for viral rescue on human MNs, which may provide the first proof of principle for the treatment of GAN using gene therapy. ..
- RNA polymerase II transcription in trypanosomesARTHUR GUNZL; Fiscal Year: 2013..Moreover, a thorough understanding of trypanosome gene expression will help to control the parasite in the long term. ..
- Structure and Mechanism of SAM-responsive RiboswitchesRobert T Batey; Fiscal Year: 2013..A deeper knowledge of how RNA specifically interacts with small molecules will help pave the way for a new generation of therapeutics that target non-protein coding RNAs that are pervasive in both bacteria and eukaryotes. ..
- Development of quantitative multiplex RNA in situ hybridizationThomas Tuschl; Fiscal Year: 2013....
- PTIP as an epigenetic regulator in male meiosisGuo Zhang Zhu; Fiscal Year: 2013..Furthermore, collected information may offer insights into unexplained (or idiopathic) infertility in men and may lead to new strategies for male contraception and assisted reproduction. ..
- Coronavirus RNA ReplicationDAVID ALVIN BRIAN; Fiscal Year: 2012..Knowing in detail what molecular interactions lead to coronavirus replication and recombination, the focus of this proposal, are essential for the development of stable and safe recombinant vaccines and the design of anti-viral drugs. ..
- Function of mRNA Editing in TrypanosomesStephen L Hajduk; Fiscal Year: 2010..Together these studies will provide the first analysis of the role of RNA editing in protein diversification in trypanosomes and is likely to lead to the discovery of novel mitochondrial proteins. ..
- SPLICING OF MRNA PRECURSORSMichael R Green; Fiscal Year: 2013....
- Axonal Transport Deficits during Hereditary Spastic ParaplegiaGERARDO ANDRES MORFINI; Fiscal Year: 2013..The ultimate goal of this project is to define disease mechanisms and identify novel therapeutic targets in HSP. ..
- Role of dyskerin in oral epithelial homeostasisFaizan Alawi; Fiscal Year: 2013....
- FUNCTION AND REGULATION OF OSTEONECTIN IN BONEAnne M Delany; Fiscal Year: 2013..Information obtained from these studies could be used to identify novel targets for therapeutic intervention in the treatment of osteoporosis, and may be used to identify individuals at risk for developing osteoporosis. ..
- Epigenome Mapping in Cortical InterneuronsSchahram Akbarian; Fiscal Year: 2013....
- Agnoprotein in JC virus virion biogenesis and replicationMahmut Safak; Fiscal Year: 2012....
- CODING IN AUDITORY NEURONS: EFFECTS OF AMINO ACIDSDonald M Caspary; Fiscal Year: 2013..It is hoped that these studies could eventually result in the development of selective new drugs to improve speech understanding in a subset of elderly individuals. ..
- Anti-Idiotype Therapy of Human B Cell MalignancyRonald Levy; Fiscal Year: 2007..Again, our eventual intention[unreadable] will be to design new clinical trials based on the enhanced potency of the vaccine maneuver provided DCs.[unreadable]..
- AGE RELATED SYNAPTIC CHANGES IN THE AUDITORY BRAINSTEMRobert Helfert; Fiscal Year: 1999....
- Assessing space and feature based attention with fMRI and multivoxel pattern analJohn Serences; Fiscal Year: 2010....
- High Throughput Protein Production by Novel E. coli Expression-Secretion SystemWILLIAM MACCONNELL; Fiscal Year: 2006..They will improve protein production and yield high quality protein. These products will be essentially ready for market at the end of Phase II. [unreadable] [unreadable] [unreadable]..
- Non-coding RNAs in the epigenetics of human centromere formationPETER WARBURTON; Fiscal Year: 2009..These epigenetic marks are currently unknown in human cells, and their discovery will provide great insight into the requirements for centromere formation and function. ..
- Comprehensive Mutational Analysis of the Cancer GenomeDennis Ballinger; Fiscal Year: 2004..abstract_text> ..
- Effects of sensorineural loss on robust speech codingMichael Heinz; Fiscal Year: 2007..The difficulty hearing-impaired listeners have in understanding speech in complex acoustic environments may be due in part to a reduced ability to segregate sound sources based on voice pitch. ..
- Comprehensive transcriptome analysis for Porphyromonas gingivalisTsute Chen; Fiscal Year: 2009..Studies proposed in this application will specifically identify important genetic traits of oral pathogens that cause these diseases. By understanding more about these traits, better treatment and prevention methods can be developed. ..
- 'RECODING: DYNAMIC REPROGRAMMING OF GENETIC READOUT'John Atkins; Fiscal Year: 2004..To keep monitoring newly reported sequences for potential new cases and to respond to suggestions of others who have encountered new cases. ..
- DEVELOPMENT OF SOUND LOCALIZATIONCatherine Carr; Fiscal Year: 2000..This application is also supported by the chair of the Zoology department at the University of Maryland. ..
- The Human Colorectal InstabilitomeStephen Meltzer; Fiscal Year: 2007..c.i To utilize PCA components to find genes segregating with MSI status, and SAM to identify genes significantly differentially expressed among these three groups. ..
- Taste Coding by Neural Circuitry in the Brain StemPATRICIA DI LORENZO; Fiscal Year: 2005..By describing the taste responsivity of inputs and outputs of NTS cells, data from this project will help provide an understanding of information processing in the NTS. ..