drug utilization

Summary

Summary: The utilization of drugs as reported in individual hospital studies, FDA studies, marketing, or consumption, etc. This includes drug stockpiling, and patient drug profiles.

Top Publications

  1. ncbi Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
    Herman Goossens
    ESAC Management Team, Department of Microbiology, University of Antwerp, B 2610 Antwerp, Belgium
    Lancet 365:579-87. 2005
  2. pmc Improved diagnostic testing and malaria treatment practices in Zambia
    Davidson H Hamer
    Center for International Health and Development, Boston University School of Public Health, Boston, Mass 02118, USA
    JAMA 297:2227-31. 2007
  3. ncbi Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship
    Timothy H Dellit
    Harborview Medical Center and the University of Washington, Seattle, USA
    Clin Infect Dis 44:159-77. 2007
  4. ncbi Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial
    Philipp Schuetz
    Department of Internal Medicine, Kantonsspital Aarau, Tellstrasse, CH 5001 Aarau, Switzerland
    JAMA 302:1059-66. 2009
  5. pmc Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study
    Valérie D'Acremont
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Malar J 10:107. 2011
  6. ncbi Potentially inappropriate medication use among elderly home care patients in Europe
    Daniela Fialova
    Department of Geriatrics and Gerontology, 1st Medical Faculty, Charles University, Prague, Czech Republic
    JAMA 293:1348-58. 2005
  7. pmc A European study on the relationship between antimicrobial use and antimicrobial resistance
    Stef L A M Bronzwaer
    National Institute of Public Health and the Environment, Department of Infectious Disease Epidemiology, Postbak 75, PO Box 1, Antonie van Leeuwenhoeklaan 9, 3720 BA Bilthoven, The Netherlands
    Emerg Infect Dis 8:278-82. 2002
  8. ncbi The new Swedish Prescribed Drug Register--opportunities for pharmacoepidemiological research and experience from the first six months
    Björn Wettermark
    Division of Clinical Pharmacology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
    Pharmacoepidemiol Drug Saf 16:726-35. 2007
  9. ncbi European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009)
    Niels Adriaenssens
    Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp, Belgium
    J Antimicrob Chemother 66:vi3-12. 2011
  10. ncbi Drug utilization pattern of Chinese herbal medicines in a general hospital in Taiwan
    L C Chen
    Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan
    Pharmacoepidemiol Drug Saf 14:651-7. 2005

Detail Information

Publications310 found, 100 shown here

  1. ncbi Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
    Herman Goossens
    ESAC Management Team, Department of Microbiology, University of Antwerp, B 2610 Antwerp, Belgium
    Lancet 365:579-87. 2005
    ..Our aim was to assess outpatient use of antibiotics and the association with resistance...
  2. pmc Improved diagnostic testing and malaria treatment practices in Zambia
    Davidson H Hamer
    Center for International Health and Development, Boston University School of Public Health, Boston, Mass 02118, USA
    JAMA 297:2227-31. 2007
    ....
  3. ncbi Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship
    Timothy H Dellit
    Harborview Medical Center and the University of Washington, Seattle, USA
    Clin Infect Dis 44:159-77. 2007
  4. ncbi Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial
    Philipp Schuetz
    Department of Internal Medicine, Kantonsspital Aarau, Tellstrasse, CH 5001 Aarau, Switzerland
    JAMA 302:1059-66. 2009
    ..In previous smaller trials, a procalcitonin (PCT) algorithm reduced antibiotic use in patients with lower respiratory tract infections (LRTIs)...
  5. pmc Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study
    Valérie D'Acremont
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Malar J 10:107. 2011
    ..Presumptive treatment of all febrile patients with anti-malarials leads to massive over-treatment. The aim was to assess the effect of implementing malaria rapid diagnostic tests (mRDTs) on prescription of anti-malarials in urban Tanzania...
  6. ncbi Potentially inappropriate medication use among elderly home care patients in Europe
    Daniela Fialova
    Department of Geriatrics and Gerontology, 1st Medical Faculty, Charles University, Prague, Czech Republic
    JAMA 293:1348-58. 2005
    ..In contrast, in Europe little information is available about potentially inappropriate medication use and is based on small studies with uncertain generalizability...
  7. pmc A European study on the relationship between antimicrobial use and antimicrobial resistance
    Stef L A M Bronzwaer
    National Institute of Public Health and the Environment, Department of Infectious Disease Epidemiology, Postbak 75, PO Box 1, Antonie van Leeuwenhoeklaan 9, 3720 BA Bilthoven, The Netherlands
    Emerg Infect Dis 8:278-82. 2002
    ..Our results show that in Europe antimicrobial resistance of S. pneumoniae to penicillin is correlated with use of beta-lactam antibiotics and macrolides...
  8. ncbi The new Swedish Prescribed Drug Register--opportunities for pharmacoepidemiological research and experience from the first six months
    Björn Wettermark
    Division of Clinical Pharmacology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
    Pharmacoepidemiol Drug Saf 16:726-35. 2007
    ..To describe the content and potentials of the new Swedish national register on prescribed and dispensed medicines...
  9. ncbi European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009)
    Niels Adriaenssens
    Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp, Belgium
    J Antimicrob Chemother 66:vi3-12. 2011
    ..To describe total outpatient systemic antibiotic use in Europe from 1997 to 2009 and to analyse statistically trends of total use and composition of use over time...
  10. ncbi Drug utilization pattern of Chinese herbal medicines in a general hospital in Taiwan
    L C Chen
    Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan
    Pharmacoepidemiol Drug Saf 14:651-7. 2005
    b>Drug utilization studies are important for the optimization of drug therapy and have received a great attention in recent years...
  11. ncbi Ten recommendations to improve use of medicines in developing countries
    R Laing
    Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Health Policy Plan 16:13-20. 2001
    ..Sufficient evidence is now available to persuade policy-makers that it is possible to promote rational drug use. If such effective strategies are followed, the quality of health care can be improved and drug expenditures reduced...
  12. ncbi Influences on GPs' decision to prescribe new drugs-the importance of who says what
    Helen Prosser
    Prescribing Research Group, Department of Pharmacology, The Infirmary, 70 Pembroke Place, Liverpool L69 3GF, UK
    Fam Pract 20:61-8. 2003
    ..The aim of this study was to understand the range of factors that influence GPs' uptake of new drugs..
  13. ncbi Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians
    R Gonzales
    Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    JAMA 278:901-4. 1997
    ..How frequently antibiotics are prescribed for these conditions and for and by whom is not known...
  14. pmc Antimicrobial drug use and resistance in Europe
    Nienke van de Sande-Bruinsma
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Emerg Infect Dis 14:1722-30. 2008
    ..Ecologic studies based on routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial drug consumption at a national level in Europe...
  15. pmc Oseltamivir prescription and regulatory actions vis-à-vis abnormal behavior risk in Japan: drug utilization study using a nationwide pharmacy database
    Hisashi Urushihara
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan
    PLoS ONE 6:e28483. 2011
    ..The number of reports associated with zanamivir increased in proportion to increased dispensation of this drug (11 to 114 cases)...
  16. pmc Use of guideline-recommended therapies for heart failure in the Medicare population
    Lisa D DiMartino
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Clin Cardiol 33:400-5. 2010
    ..Most information about the use of guideline-recommended therapies for heart failure reflects what occurred at discharge after an inpatient stay...
  17. ncbi Comparison of antiepileptic drug prescribing in children in three European countries
    Yingfen Hsia
    Centre for Paediatric Pharmacy Research, The School of Pharmacy, University of London and Institute of Child Health, University College London, London, United Kingdom
    Epilepsia 51:789-96. 2010
    ..However, evidence of its use at a multinational level is limited. This study aims to characterize AED prescribing in the young in three European countries and to assess the capacity of drug safety surveillance...
  18. ncbi Examination of opioid prescribing in Australia from 1992 to 2007
    M Leong
    Drug Health Service, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Intern Med J 39:676-81. 2009
    ..There is some evidence to support efficacy for chronic non-malignant pain, but community and individual harms are increasingly reported...
  19. ncbi [Bacterial resistance and antibiotic prescriptions: perceptions, attitudes and knowledge of a sample of French GPs]
    C Pulcini
    Service d Infectiologie, Hopital l Archet 1, CHU de Nice, 151 Route Saint Antoine de Ginestiere, BP 3079, 06202 Nice Cedex 3, France
    Med Mal Infect 40:703-9. 2010
    ..The study's objective was to assess General Practitioners' (GPs) perceptions of their antibiotic prescribing practice and of bacterial resistance...
  20. ncbi Evaluation of a national programme to reduce inappropriate use of antibiotics for upper respiratory tract infections: effects on consumer awareness, beliefs, attitudes and behaviour in Australia
    Sonia E Wutzke
    National Prescribing Service Ltd, PO Box 1147, Strawberry Hills, Sydney, NSW 2012, Australia
    Health Promot Int 22:53-64. 2007
    ..44 million in 2001-02) and, specifically, by a decline among the nine antibiotics commonly used for URTI such that by 2003 nationally 216,000 fewer prescriptions for URTI are written each year by general practitioners...
  21. pmc High prevalence of antibiotic resistance in commensal Escherichia coli among children in rural Vietnam
    Oliver James Dyar
    Division of Global Health IHCAR, Department of Public Health Sciences, Karolinska Institutet, Nobels väg 9, 171 77 Stockholm, Sweden
    BMC Infect Dis 12:92. 2012
    ..We investigated the prevalence of resistance in commensal Escherichia coli in preschool children in rural Vietnam, and factors associated with carriage of resistant bacteria...
  22. pmc Nonsteroidal anti-inflammatory drug use among persons with chronic kidney disease in the United States
    Laura Plantinga
    Department of Medicine, University of California, San Francisco, California, USA
    Ann Fam Med 9:423-30. 2011
    ..Because avoidance of nonsteroidal anti-inflammatory drugs (NSAIDs) is recommended for most individuals with chronic kidney disease (CKD), we sought to characterize patterns of NSAID use among persons with CKD in the United States...
  23. ncbi Antibiotic resistance amongst healthcare-associated pathogens in China
    Saber Yezli
    BIOQUELL UK Ltd, 52 Royce Close, West Portway, Andover, Hampshire SP10 3RX, UK
    Int J Antimicrob Agents 40:389-97. 2012
    ..There is a need for effective infection prevention and control measures and strict use of antibiotics in China to control the rise and spread of antibiotic resistance in the country...
  24. ncbi Scottish Antimicrobial Prescribing Group (SAPG): development and impact of the Scottish National Antimicrobial Stewardship Programme
    Dilip Nathwani
    Infection Unit, East Block, Level 4, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Int J Antimicrob Agents 38:16-26. 2011
    ....
  25. ncbi The challenges of antimicrobial drug resistance in Greece
    Spiros Miyakis
    Infectious Diseases Clinic, Third Department of Medicine, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece
    Clin Infect Dis 53:177-84. 2011
    ..Awareness of resistance patterns and organisms prevailing locally by reporting laboratories and treating physicians is important...
  26. ncbi Ciprofloxacin use in neonates: a systematic review of the literature
    Florentia Kaguelidou
    Department of Pediatric Pharmacology and Pharmacogenetics, Hopital Robert Debre, APHP INSERM CIC9202 Université Paris 7, Paris, France
    Pediatr Infect Dis J 30:e29-37. 2011
    ..Given the concerns about its toxicity in this population and the necessity for its use in specific clinical situations, we conducted a systematic review of the use of ciprofloxacin in neonates...
  27. ncbi Assessing prescribing and patient care indicators for children under five years old with malaria and other disease conditions in public primary health care facilities
    Stephen Elias Damson Nsimba
    Department of Clinical Pharmacology, School of Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Southeast Asian J Trop Med Public Health 37:206-14. 2006
    ..All these can be achieved through well planned health education training programs...
  28. ncbi Regional variation in outpatient antibiotic prescribing in Germany
    W V Kern
    Center for Infectious Diseases and Travel Medicine, University Hospital, Hugstetter Str 55, 79106, Freiburg, Germany
    Infection 34:269-73. 2006
    ..We assessed regional variation in outpatient antibiotic use within Germany both for overall use as well as for specific antibiotic drug classes...
  29. ncbi Antidepressant utilisation patterns and determinants of short-term and non-psychiatric use in the Finnish general adult population
    Sinikka Sihvo
    STAKES National Research and Development Centre for Welfare and Health, Helsinki, Finland
    J Affect Disord 110:94-105. 2008
    ..The aim was to study utilisation patterns and determinants of antidepressant use in the general population >30 years, especially short-term use or use not related to known psychiatric morbidity...
  30. ncbi Prescriptions as a proxy for asthma in children: a good choice?
    Falk Hoffmann
    Center for Social Policy Research, University of Bremen, Germany
    Eur J Clin Pharmacol 66:307-13. 2010
    ..Our objective was to critically assess and discuss various aspects of identifying children with asthma using prescription data...
  31. ncbi Antibiotic use and upper respiratory infections: a survey of knowledge, attitudes, and experience in Wisconsin and Minnesota
    Edward A Belongia
    Marshfield Medical Research Foundation and Marshfield Clinic, Marshfield, Wisconsin 54449, USA
    Prev Med 34:346-52. 2002
    ..Public attitudes and expectations contribute to inappropriate antibiotic prescribing and antibiotic resistance. This study assessed knowledge, attitudes, and experiences regarding antibiotic use for respiratory infection or illness...
  32. pmc Trends in prescribing and utilization of statins and other lipid lowering drugs across Europe 1997-2003
    T Walley
    Department of Pharmacology and Therapeutics, University of Liverpool, 70 Pembrooke Place, Liverpool L69 3GF, UK
    Br J Clin Pharmacol 60:543-51. 2005
    ..To describe trends in utilization and prescribing of statins and other lipid lowering drugs across Europe from data in routine administrative databases...
  33. ncbi A pilot study of antibiotic cycling in the community hospital setting
    Lou Ann Bruno-Murtha
    Department of Medicine, Cambridge Health Alliance Harvard Medical School, Cambridge, Massachusetts, USA
    Infect Control Hosp Epidemiol 26:81-7. 2005
    ..To assess the feasibility of a quarterly antibiotic cycling program at two community hospitals and to evaluate its safety and impact on antibiotic use, expenditures, and resistance...
  34. ncbi Epilepsy in the United Kingdom: seizure frequency and severity, anti-epileptic drug utilization and impact on life in 1652 people with epilepsy
    N F Moran
    Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Seizure 13:425-33. 2004
    ..Secondly, to determine if these characteristics differ according to age...
  35. ncbi The European surveillance of antimicrobial consumption (ESAC) point-prevalence survey of antibacterial use in 20 European hospitals in 2006
    Faranak Ansari
    Division of Clinical and Population Sciences and Education, University of Dundee, Dundee, Great Britain
    Clin Infect Dis 49:1496-504. 2009
    ..We aimed to standardize a method for surveillance of antibacterial use in hospitals from different health care systems and to identify targets for quality improvement...
  36. ncbi The Pharmacy-based Cost Group model: validating and adjusting the classification of medications for chronic conditions to the Dutch situation
    Leida M Lamers
    Department of Health Policy and Management, Erasmus MC University Medical Center Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Health Policy 68:113-21. 2004
    ..Of the 22 chronic conditions in this classification, 13 were included in the PCG model that is currently used in the Netherlands...
  37. pmc An observational study of antibiotic prescribing behavior and the Hawthorne effect
    Rita Mangione-Smith
    UCLA, Department of Pediatrics, Los Angeles, CA 90095 1752, USA
    Health Serv Res 37:1603-23. 2002
    ..To assess whether prospective, observational study procedures, including questionnaires and audio recording, are associated with different patterns of physician diagnostic decision making and antibiotic prescribing...
  38. pmc Case management of malaria fever in Cambodia: results from national anti-malarial outlet and household surveys
    Megan Littrell
    Population Services International, Department of Malaria and Child Survival, P O Box 14355 00800, Nairobi, Kenya
    Malar J 10:328. 2011
    ..Spread of artemisinin resistance would threaten recent gains in global malaria control. As such, the anti-malarial market and malaria case management practices in Cambodia have global significance...
  39. ncbi Unlicensed and off-label drug use in a paediatric ward of a general hospital in the Netherlands
    G W 't Jong
    Pharmacoepidemiology Unit, Department of Internal Medicine, Epidemiology and Biostatistics, Erasmus Medical Centre Rotterdam, The Netherlands
    Eur J Clin Pharmacol 58:293-7. 2002
    ..We determined the extent and nature of use of unlicensed drugs and off-label prescriptions in children in a general hospital in the Netherlands...
  40. ncbi Impact of antimicrobial stewardship in critical care: a systematic review
    Reham Kaki
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Antimicrob Chemother 66:1223-30. 2011
    ..To evaluate the current state of evidence for antimicrobial stewardship interventions in the critical care unit...
  41. pmc Trends in antibiotic use among outpatients in New Delhi, India
    Anita Kotwani
    Department of Pharmacology, V P Chest Institute, University of Delhi, Delhi, India
    BMC Infect Dis 11:99. 2011
    ..There is much ad-hoc information about the inappropriate consumption of antibiotics, over-the-counter availability, and inadequate dosage but there is very little actual evidence of community practices...
  42. ncbi Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries
    Benedikt Huttner
    Infection Control Programme, Geneva University Hospitals and Medical School, Geneva, Switzerland
    Lancet Infect Dis 10:17-31. 2010
    ..Although the most effective interventions and potential adverse outcomes remain unclear, public campaigns can probably contribute to more careful use of antibiotics in outpatients, at least in high-prescribing countries...
  43. pmc Point-of-care C-reactive protein testing and antibiotic prescribing for respiratory tract infections: a randomized controlled trial
    Jochen W L Cals
    Department of General Practice, School for Public Health and Primary Care CAPHRI, Maastricht University Medical Centre, Maastricht, The Netherlands
    Ann Fam Med 8:124-33. 2010
    ..We evaluated the effect of CRP assistance in antibiotic prescribing strategies-including delayed prescribing-in the management of LRTI and rhinosinusitis...
  44. pmc Use of opioid medications for chronic noncancer pain syndromes in primary care
    M Carrington Reid
    Clinical Epidemiology Unit, VA Connecticut Healthcare System, West Haven Conn 06516, USA
    J Gen Intern Med 17:173-9. 2002
    ..We also sought to determine the proportion of patients who manifested prescription opioid abuse behaviors and the factors associated with these behaviors...
  45. pmc Tensions in antibiotic prescribing: pitting social concerns against the interests of individual patients
    Joshua P Metlay
    Philadelphia Veterans Affairs Medical Center, University of Pennsylvania School of Medicine, 712 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Gen Intern Med 17:87-94. 2002
    ..However, optimal use from the perspective of the community (reserving newer agents for future use) is not always consistent with optimal use from the perspective of the individual patient (prescribing newer, broader agents)...
  46. ncbi Prevalence and correlates of psychotropic drug use in Dutch nursing-home patients with dementia
    Renate M Nijk
    Center for Family Medicine, Geriatric Care and Public Health, Radboud University Nijmegen, Medical Centre, Nijmegen, The Netherlands
    Int Psychogeriatr 21:485-93. 2009
    ..The aim of this study was to determine the prevalence and correlates of psychotropic drug use in Dutch nursing home patients with dementia...
  47. ncbi Epidemiologic features of antipsychotic prescribing to children and adolescents in primary care in the United Kingdom
    Fariz Rani
    Centre for Pediatric Pharmacy Research, The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, United Kingdom
    Pediatrics 121:1002-9. 2008
    ..The goal was to investigate the epidemiologic features of antipsychotic prescribing to children and adolescents in general practice in the United Kingdom...
  48. ncbi Socioeconomic determinants of regional differences in outpatient antibiotic consumption: evidence from Switzerland
    Massimo Filippini
    Department of Economics, University of Lugano, Switzerland
    Health Policy 78:77-92. 2006
    ..The incidence of bacterial infections is also relevant. Appropriate policies affecting antibiotic consumption in the community can be designed by looking at crucial determinants in the model and their related impact...
  49. pmc Antimicrobial stewardship programs in health care systems
    Conan MacDougall
    Department of Pharmacy, School of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298, USA
    Clin Microbiol Rev 18:638-56. 2005
    ..When instituting an antimicrobial stewardship program, a hospital should tailor its choice of strategies to its needs and available resources...
  50. pmc Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy
    Alexander N O Dodoo
    Centre for Tropical Clinical Pharmacology and Therapeutics, University of Ghana Medical School, P, O, Box KB 4236, Accra, Ghana
    Malar J 8:2. 2009
    ..Ghana implemented first-line therapy of artesunate-amodiaquine in 2005. Drug utilization data is an important component of determining drug safety, and this paper describes how anti-malarials were ..
  51. ncbi Variation in nursing home antipsychotic prescribing rates
    Paula A Rochon
    Kunin Lunenfeld Applied Research Unit, Baycrest, 3560 Bathurst Street, Toronto, Ontario, Canada
    Arch Intern Med 167:676-83. 2007
    ..We explored variation in the use of antipsychotic therapy across nursing homes in Ontario, Canada, and determined if prescribing decisions were based on clinical indications...
  52. pmc Prescribing indicators for UK general practice: Delphi consultation study
    S M Campbell
    National Primary Care Research and Development Centre, University of Manchester, Manchester M13 9PL
    BMJ 321:425-8. 2000
    ..To identify prescribing indicators based on prescribing analysis and cost (PACT) data that have face validity for measuring quality or cost minimisation...
  53. ncbi Socioeconomic inequalities in drug utilization for Sweden: evidence from linked survey and register data
    Martin Nordin
    Department of Economics, Lund University, PO Box 7082, 220 07 Lund, Sweden
    Soc Sci Med 77:106-17. 2013
    This study analyzes the socioeconomic gradient in drug utilization. We use The Swedish Prescribed Drug Register, merged with the Survey of Living Conditions (the ULF), and the study sample consists of 8138 individuals...
  54. ncbi Agreement between self-reported data on medicine use and prescription records vary according to method of analysis and therapeutic group
    Merete Willemoes Nielsen
    University of Copenhagen, Faculty of Pharmaceutical Sciences, Department of Pharmacology and Pharmacotherapy, Section for Social Pharmacy, Universitetsparken 2, Copenhagen, Denmark
    J Clin Epidemiol 61:919-24. 2008
    ..This study compared national self-reported data on medicine use and national prescription records at the individual level...
  55. pmc Risk factors for antibiotic-resistant E. coli in children in a rural area
    J C Seidman
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Epidemiol Infect 137:879-88. 2009
    ..Frequent, low-cost surveillance of commensal resistance can guide development of locally appropriate treatment guidelines. School-based hygiene programmes should be considered as means of limiting the spread of antibiotic resistance...
  56. ncbi [Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso]
    L T Ouedraogo
    Departement de sante publique, UFR SDS, Universite de Ouagadougou, BP 5705 Ouagadougou 01, Burkina Faso
    Bull Soc Pathol Exot 101:124-7. 2008
    ....
  57. ncbi Factors affecting the uptake of new medicines in secondary care - a literature review
    D Chauhan
    Office of Health Economics, London, UK
    J Clin Pharm Ther 33:339-48. 2008
    ..However, the reasons for relatively low precribing levels are poorly understood. This review explores the determinants of uptake of new medicines in secondary care...
  58. ncbi Impact of the French campaign to reduce inappropriate ambulatory antibiotic use on the prescription and consultation rates for respiratory tract infections
    Pierre Chahwakilian
    Infection Control Programme, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
    J Antimicrob Chemother 66:2872-9. 2011
    ..To assess long-term trends in the volume of ambulatory antibiotic prescriptions and prescription and consultation rates for respiratory tract infections (RTIs) in France in relation to the yearly public antibiotic campaign since 2002...
  59. ncbi Changes in drug utilization following the outpatient prescription drug cost-sharing program--evidence from Taiwan's elderly
    Shuen Zen Liu
    Department of Accounting, College of Management, National Taiwan University, Taiwan, ROC
    Health Policy 68:277-87. 2004
    This paper examines changes in drug utilization following Taiwan's newly implemented National Health Insurance (NHI) outpatient prescription drug cost-sharing program for persons over 65 years old...
  60. ncbi Prescription drug use during pregnancy: a population-based study in Regione Emilia-Romagna, Italy
    Joshua J Gagne
    Department of Health Policy, Jefferson Medical College, 1015 Walnut Street, Suite 115, Philadelphia, PA 19107, USA
    Eur J Clin Pharmacol 64:1125-32. 2008
    b>Drug utilization studies in pregnant women are crucial to inform pharmacovigilance efforts in human teratogenicity...
  61. ncbi Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil
    Djanilson Barbosa Santos
    Epidemiology and Public Health, Multidisciplinary Institute of Health, Federal University of Bahia, Vitória da Conquista, Bahia, Brazil
    Eur J Clin Pharmacol 64:1111-8. 2008
    ..To investigate the use of drugs, the extent and pattern of unlicensed and off-label use, and the potential relationship between off-label drug use and adverse drug reactions in northeastern Brazil...
  62. pmc Prescription drug use during pregnancy in developed countries: a systematic review
    Jamie R Daw
    Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
    Pharmacoepidemiol Drug Saf 20:895-902. 2011
    ..To review the literature describing patterns of outpatient prescription drug use during pregnancy by therapeutic category, potential for fetal harm, and overall...
  63. pmc Surveillance and correlation of antibiotic consumption and resistance of Acinetobacter baumannii complex in a tertiary care hospital in northeast China, 2003-2011
    Jiancheng Xu
    Department of Laboratory Medicine, First Hospital of Jilin University, Changchun 130021, China
    Int J Environ Res Public Health 10:1462-73. 2013
    ..661; p < 0.001). Dedicated use of anti-pseudomonal carbapenems would be an important intervention to control the increase of CRAB...
  64. ncbi Professional education on antimicrobial prescribing: a report from the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Professional Education Subgroup
    Peter Davey
    Health Informatics Centre, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    J Antimicrob Chemother 60:i27-32. 2007
    ..Our recommendation is that this work needs to be continued through an initiative that will ensure UK collaboration on defining learning outcomes for prudent antimicrobial use for all health professionals...
  65. ncbi National trends in the outpatient treatment of children and adolescents with antipsychotic drugs
    Mark Olfson
    New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 63:679-85. 2006
    ..Although there are indications that antipsychotic drugs are increasingly used to treat children and adolescents, little is known about the characteristics of those who receive them...
  66. ncbi Influence of commercial information on prescription quantity in primary care
    Francisco Caamano
    Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Spain
    Eur J Public Health 12:187-91. 2002
    ..The objective of this study is to identify the effect of the perceived quality stated in commercial information, its uses, and how physicians perceive the influence it has on prescription amounts...
  67. ncbi Is the "low-hanging fruit" worth picking for antimicrobial stewardship programs?
    Debra A Goff
    Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, 43210, USA
    Clin Infect Dis 55:587-92. 2012
    ....
  68. ncbi [Prescribing patterns of antipsychotics in 13 French psychiatric hospitals]
    P Bret
    Service Pharmacie, Centre Hospitalier Charles Perrens, Bordeaux Cedex, France
    Encephale 35:129-38. 2009
    ..Now, they have shown other side effects and they have a higher acquisition cost than FGAs...
  69. pmc Risk of stroke and oral anticoagulant use in atrial fibrillation: a cross-sectional survey
    Tim A Holt
    Department of Primary Care Health Sciences, Oxford University, Oxford, UK
    Br J Gen Pract 62:e710-7. 2012
    ..Oral anticoagulants substantially reduce the risk of stroke in atrial fibrillation but are underutilised in current practice...
  70. ncbi Antimicrobial stewardship programs: interventions and associated outcomes
    Dimple Patel
    University of California, San Francisco School of Pharmacy, 521 Parnassus Avenue, C 152, San Francisco, CA 94143, USA
    Expert Rev Anti Infect Ther 6:209-22. 2008
    ..Antimicrobial stewardship programs are becoming increasingly associated with clear benefits and will be integral in the in-patient healthcare setting...
  71. ncbi Antimicrobial stewardship--the state of the art in 2011: focus on outcome and methods
    John E McGowan
    Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Infect Control Hosp Epidemiol 33:331-7. 2012
    ..Attention to evaluation methods must be increased to provide convincing evidence for the continuation of such programs...
  72. ncbi Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn
    Jennita Reefhuis
    N Engl J Med 354:2188-90; author reply 2188-90. 2006
  73. ncbi Prospective audit and feedback on antibiotic prescription in an adult hematology-oncology unit in Singapore
    C L Yeo
    Department of Pharmacy, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Singapore, 119228, Singapore
    Eur J Clin Microbiol Infect Dis 31:583-90. 2012
    ..Adverse outcomes-the majority unavoidable-occurred following 5.5% of accepted ASP recommendations. Safe and effective ASPs can be implemented in the complex setting of hematology-oncology inpatients...
  74. pmc Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi
    John H Amuasi
    Komfo Anokye Teaching Hospital, Kumasi, P, O, BOX KS 1934, Ghana
    Malar J 10:34. 2011
    ..Uptake of this policy in the public, private and non-governmental (NGO) retail market sectors of Burundi is relatively unknown. This study was conducted to evaluate access to national policy recommended anti-malarials...
  75. ncbi Pattern of drug utilization among hypertensives in a Nigerian teaching hospital
    K B Yusuff
    Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria
    Pharmacoepidemiol Drug Saf 14:69-74. 2005
    To describe the drug utilization pattern among hypertensive patients in a tertiary care setting, assess the short-term outcome of anti-hypertensive drugs usage and identify points for future intervention to improve outcomes.
  76. ncbi Antibiotic policy
    Inge C Gyssens
    Nijmegen Institute for Infection, Inflammation, and Immunity N4i and Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Antimicrob Agents 38:11-20. 2011
    ..Special emphasis is placed on urinary tract infections. The value and support of antibiotic committees, guidelines, ID consultants and/or antimicrobial stewardship teams to prolong the efficacy of available antibiotics will be discussed...
  77. ncbi Use of cognitive enhancement medication among northern Italian university students
    Silvana Castaldi
    University of Milan, Fondazione IRCCS Ca Granda Ospedale Maggiore di Milano, Italy
    J Addict Med 6:112-7. 2012
    ..Students who think that there is no or an acceptable risk involved in cognitive enhancement medication are more likely to take drugs and dietary supplements than those who perceive the risk as high...
  78. pmc Older patient perspectives on long-term anxiolytic benzodiazepine use and discontinuation: a qualitative study
    Joan M Cook
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 69, New York, NY 10032, USA
    J Gen Intern Med 22:1094-100. 2007
    ....
  79. ncbi Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: data from spontaneous reporting in Italy
    Francesco Salvo
    Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Messina, Italy
    J Antimicrob Chemother 60:121-6. 2007
    ..To analyse an Italian database of spontaneous reporting of suspected adverse drug reactions in order to compare the safety profile of amoxicillin and amoxicillin/clavulanic acid...
  80. ncbi Do general practitioners' consultation rates influence their prescribing patterns of antibiotics for acute respiratory tract infections?
    Svein Gjelstad
    Department of General Practice Family Medicine, Institute of Health and Society, University of Oslo, PO Box 1130, Blindern, N 0318 Oslo, Norway
    J Antimicrob Chemother 66:2425-33. 2011
    ..To examine general practitioners' (GPs') antibiotic prescribing patterns for acute respiratory tract infections (ARTIs) as compared with national guidelines. We also wanted to explore possible predictors of antibiotic prescription patterns...
  81. ncbi The association of social support at work and in private life with mental health and antidepressant use: the Health 2000 Study
    Marjo Sinokki
    Finnish Institute of Occupational Health, Lemminkäisenkatu 14 18 B, FI 20520 Turku, Finland
    J Affect Disord 115:36-45. 2009
    ..This study, carried out in Finland 2000-2003, examined the associations of low social support at work and in private life with DSM-IV depressive and anxiety disorders and subsequent antidepressant medication...
  82. pmc Impact of Medicaid prior authorization requirement for COX-2 inhibitor drugs in Nebraska
    Mark V Siracuse
    Department of Pharmacy Sciences, Creighton Health Services Research Program, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza Boyne 143H, Omaha, NE 68178, USA
    Health Serv Res 43:435-50. 2008
    ..Determine the impact of a Prior Authorization Requirement (PAR) program on Medicaid pharmacy expenditures and utilization...
  83. ncbi Emerging trends in antibiotic use in US hospitals: quality, quantification and stewardship
    Jesse T Jacob
    Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA
    Expert Rev Anti Infect Ther 8:893-902. 2010
    ..Both have implemented programmatic strategies for prudent antibiotic use. The USA appears to have implemented processes more systematically to measure the quality of antibiotic use...
  84. ncbi Assessment of drug use among pregnant women in Addis Ababa, Ethiopia
    Binyam Kebede
    Department of Pharmaceutics, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia
    Pharmacoepidemiol Drug Saf 18:462-8. 2009
    ..To assess the drug use among antenatal care (ANC) attendant pregnant women in Addis Ababa...
  85. pmc Road traffic accidents and psychotropic medication use in The Netherlands: a case-control study
    Silvia Ravera
    Department of Pharmacotherapy and Pharmaceutical Care, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    Br J Clin Pharmacol 72:505-13. 2011
    ..To examine the association between the use of commonly prescribed psychotropic medications and road traffic accident risk...
  86. ncbi Trend analysis of antimicrobial consumption and development of resistance in non-fermenters in a tertiary care hospital in Delhi, India
    Neeraj Goel
    Department of Clinical Microbiology and Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, India
    J Antimicrob Chemother 66:1625-30. 2011
    ..To study the evolution of non-fermenters in a tertiary care hospital, we undertook a retrospective 10 year (1999-2008) trend analysis of antimicrobial consumption and resistance in non-fermenters causing bacteraemia...
  87. ncbi Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings
    Carlos G Grijalva
    Department of Preventive Medicine, Vanderbilt University School of Medicine, 1500 21st Ave, Ste 2600, The Village at Vanderbilt, Nashville, TN 37232 2637, USA
    JAMA 302:758-66. 2009
    ..During the 1990s, antibiotic prescriptions for acute respiratory tract infection (ARTI) decreased in the United States. The sustainability of those changes is unknown...
  88. pmc Osteoporosis quality indicators using healthcare utilization data
    S M Cadarette
    Leslie Dan Faculty of Pharmacy, University of Toronto, Leslie L Dan Pharmacy Building, 144 College Street, Toronto, ON M5S 3M2, Canada
    Osteoporos Int 22:1335-42. 2011
    ..81) with minimal measurement error...
  89. pmc Empiric antibiotic therapy in acute uncomplicated urinary tract infections and fluoroquinolone resistance: a prospective observational study
    Cenk Aypak
    Department of Family Medicine, Ankara University, School of Medicine, Ibni Sina Hospital 06100, Ankara, Turkey
    Ann Clin Microbiol Antimicrob 8:27. 2009
    ....
  90. ncbi Anti-asthmatic drug prescriptions to an Italian paedriatic population
    Marina Bianchi
    Laboratory for Mother and Child Health, Mario Negri Pharmacological Research Institute, 20156, Milan, Italy
    Pediatr Allergy Immunol 20:585-91. 2009
    ..The approach to create subgroups on the basis of number of boxes prescribed seems to be effective in estimating asthma severity and appropriateness of the therapies...
  91. ncbi Drug utilization and polypharmacy among the elderly: a survey in Rio de Janeiro City, Brazil
    Suely Rozenfeld
    National School of Public Health Oswaldo Cruz Foundation, Rio de Janeiro, Rio de Janeiro, Brazil
    Rev Panam Salud Publica 23:34-43. 2008
    To describe drug utilization by Brazilian retirees with an emphasis on inappropriate use.
  92. ncbi Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey
    David W Kaufman
    Slone Epidemiology Unit, Boston University School of Public Health, 1010 Commonwealth Ave, Boston, MA 02215, USA
    JAMA 287:337-44. 2002
    ..Data on the range of prescription and over-the-counter drug use in the United States are not available...
  93. ncbi Is it possible to measure prescribing quality using only prescription data?
    Morten Andersen
    Research Unit for General Practice, University of Southern Denmark, Odense C
    Basic Clin Pharmacol Toxicol 98:314-9. 2006
    ..Furthermore, the statistical and epidemiological properties of prescribing quality indicators need more attention...
  94. ncbi [Increased benzodiazepine use in elderly women attending urban primary health care centers]
    Ferran Bejarano Romero
    Farmacología Clínica Direcció d Atenció Primària Tarragona Reus Institut Català de la Salut Tarragona España
    Aten Primaria 40:617-21. 2008
    ..To determine the overall prevalence of the chronic use of benzodiazepines and similar drugs in primary care...
  95. ncbi Medication use for pediatric upper respiratory tract infections
    Biswadeep Das
    Department of Pharmacology, Sikkim Manipal Institute of Medical Sciences, 5th Mile, Tadong, Gangtok, Sikkim, India
    Fundam Clin Pharmacol 20:385-90. 2006
    ..The main aim of the initiative is the need for more rational medicine use in URTIs in children for improvement of clinical effectiveness, cost effectiveness and reduction of potential useless risk of side effects...
  96. ncbi Trends in cardiovascular drug utilization and drug expenditures in Canada between 1996 and 2001
    Cynthia A Jackevicius
    Pharmacy Department, University Health Network Toronto General Hospital, Toronto, Ontario, Canada
    Can J Cardiol 19:1359-66. 2003
    There is increasing interest in studying trends in drug utilization because drug costs are the fastest growing sector of the health care system.
  97. ncbi Using multiple data features improved the validity of osteoporosis case ascertainment from administrative databases
    Lisa M Lix
    Manitoba Centre for Health Policy, University of Manitoba, Canada
    J Clin Epidemiol 61:1250-60. 2008
    ..The aim was to construct and validate algorithms for osteoporosis case ascertainment from administrative databases and to estimate the population prevalence of osteoporosis for these algorithms...
  98. ncbi Trends in acute otitis media-related health care utilization by privately insured young children in the United States, 1997-2004
    Fangjun Zhou
    National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mail Stop E 52, Atlanta, GA 30333, USA
    Pediatrics 121:253-60. 2008
    ..The goal was to estimate the population effect of 7-valent pneumococcal conjugate vaccine on rates of acute otitis media-related ambulatory visits and antibiotic prescriptions for <2-year-old children enrolled in private insurance plans...
  99. ncbi Improving antibiotic use in low-income countries: an overview of evidence on determinants
    Aryanti Radyowijati
    Consultants for Health and Development, Sleedoorntuin 7, 2317 MV Leiden, The Netherlands
    Soc Sci Med 57:733-44. 2003
    ..Strategies that lean too heavily on professional education are unlikely to result in large-scale or long-lasting improvement...
  100. ncbi Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use
    Melinda M Neuhauser
    Department of Clinical Sciences and Administration, University of Houston College of Pharmacy, Houston, Tex, USA
    JAMA 289:885-8. 2003
    ..Previous surveillance studies have documented increasing rates of antimicrobial resistance in US intensive care units (ICUs) in the early 1990s...
  101. ncbi Rational use of drugs: prescribing and dispensing practices at public health facilities in Lao PDR
    Bounxou Keohavong
    Food and Drug Department, Ministry of Health, Simuang Road, Vientiane, Lao PDR
    Pharmacoepidemiol Drug Saf 15:344-7. 2006
    ..To evaluate the rational use of drug (RUD) patterns with a focus on prescribing and dispensing practices for providing information to the policy makers for further planning and identifying intervention strategies...

Research Grants66

  1. A rational approach to liver toxicity monitoring in methotrexate users
    Gabriela Schmajuk; Fiscal Year: 2013
    ..Her research agenda will address the questions of quality of care, drug utilization, and drug safety for patients with rheumatic diseases...
  2. Data Infrastructure for Post-Marketing Comparative Effectiveness Studies
    SEAN P HENNESSY; Fiscal Year: 2010
    ..Further, to demonstrate the utility of this newly extended database, the investigators propose to perform drug utilization and comparative effectiveness research using these newly linked data...
  3. Tools for Optimizing Prescribing, Monitoring and Education
    Bruce L Lambert; Fiscal Year: 2010
    ..integrate, test, deploy and disseminate tools and training materials in five key areas: drug formularies, drug utilization review, lab-pharmacy linkages, N-of-1 trials and pharmacoeconomics...
  4. Medicare Drug Benefits and High Cost Medications: Antipsychotics Under Part D
    Vicki Fung; Fiscal Year: 2013
    ..This study provides a unique opportunity to link Part D drug utilization with clinical event and medical spending data for a large, well-defined population of Medicare beneficiaries ..
  5. Evaluating Psychotropic Oversight on the Safety of Children in Foster Care
    THOMAS I MACKIE; Fiscal Year: 2012
    ..e., universal mental health evaluation, prior authorization, mandatory secondary opinion, and drug utilization reviews) adopted and organizational resources (i.e...
  6. Comparative Effectiveness of Economic Incentives for Heart Disease Prevention
    John B Wong; Fiscal Year: 2012
    ..Value-based insurance to eliminate economic barriers (e.g., drug copayments has been found to enhance drug utilization), and providing economic incentives has been found to promote behavior change...
  7. Clinical and Social Implications of Cost Sharing for Cancer Drugs
    Yu Ning Wong; Fiscal Year: 2012
    ..is to develop a multidisciplinary research program to understand the impact of insurance design on cancer drug utilization and clinical outcomes...
  8. Outcomes of beta blockers after myocardial infarction in nursing home residents
    Michael A Steinman; Fiscal Year: 2013
    ..in the United States;(2) claims data on inpatient diagnoses and services from Medicare Part A;and (3) drug utilization data from Medicare Part D and from a private nursing home chain (Manor Care), which captures drug use during ..
  9. Issues in Medicare Part D Selection
    JULIA SAMANTHA SHOEMAKER; Fiscal Year: 2011
    ..of the program in (1) enrollment of beneficiaries eligible to receive the LIS, (2) the impact on drug utilization among LIS participants, and (3) the subsequent enrollment among beneficiaries who failed to enroll at their ..
  10. Health Implications of MTM Eligibility Criteria
    JUNLING NONE WANG; Fiscal Year: 2013
    ..This result is not surprising considering that MTM eligibility criteria are based predominantly on previous drug utilization and costs, and racial and ethnic minorities historically tend to use fewer prescription drugs and incur lower ..
  11. Medicare Part D Cost-Sharing and Treatment of Mental Disorders Among Disabled Dua
    Julie Marie Donohue; Fiscal Year: 2010
    ..The objectives of this study are to examine the impact of the increased co-payments on (1) prescription drug utilization and expenditure patterns, and (2) patterns in health service utilization and expenditures among dually ..
  12. The Anticipatory Effects of Medicare Part D on Drug Utilization
    ABBY ELIZABETH ALPERT; Fiscal Year: 2010
    ..one of the program's primary aims was to expand access to prescription drugs, evaluating the impact on drug utilization is of first-order importance...
  13. Dynamics of Plan Choice and Prescription Drug Utilization in Medicare Part D
    Jonathan Gruber; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Dynamics of Plan Choice and Prescription Drug Utilization in Medicare Part D...
  14. The Impact of Medicaid Reimbursement Policies on Pharmaceutical Spending
    ABBY ELIZABETH ALPERT; Fiscal Year: 2013
    ..The project will use Medicaid State Drug Utilization data from CMS for 1994-2004 which tracks drug utilization at the level of the National Drug Code (NDC) for ..
  15. EFFECTS OF DIFFERENTIAL COST SHARING IN THE ELDERLY
    Stephen Soumerai; Fiscal Year: 1999
    ..drugs, specifically angiotensin converting enzyme inhibitors (ACEI) and calcium channel blockers (CCB), on drug utilization and drug switching in elderly recipients of these drugs (N approximately 160,000)...
  16. Attentional Bias Modification: Efficacy and Mechanisms of Action in Cocaine Addic
    ANDREW ROBERT MAYER; Fiscal Year: 2013
    ..cue reactivity or decreased inhibitory control or increased fcMRI) are more predictive of relapse and drug utilization (Exploratory Aim 1)...
  17. EFFECTIVENESS OF RETROSPECTIVE DRUG UTILIZATION REVIEW
    BRIAN STROM; Fiscal Year: 1999
    ..b>Drug utilization review (DUR) is a procedure that seeks to reduce the consequences of improper prescribing...
  18. BOTANICAL/DRUG INTERACTIONS IN HIV: GLUCURONIDATION
    Philip Smith; Fiscal Year: 2004
    ..Such interactions may also be beneficial, if they provided mechanisms to reduce drug utilization or ameliorate some adverse effects of conventional drugs...
  19. EFFECT OF MEDICAID DRUG COPAYMENTS ON OUTCOMES AND COSTS
    Neil Jordan; Fiscal Year: 2000
    ..by states, and studies suggest that beneficiary cost sharing has led to a decrease in prescription drug utilization. What is less clear is the effect of copayments on utilization of other "substitute" medical services, such ..
  20. Changes in Cardiovascular Care and Outcomes in Eight Years after Medicare Part D
    Stephen B Soumerai; Fiscal Year: 2013
    ..Study measures will include demographic and clinical attributes, drug and non-drug utilization, cost-related medication nonadherence, acute hospital events, and perceived health status...
  21. ASSESSING AMBULATORY DUR COST EFFECTIVENESS
    Jacques Tremblay; Fiscal Year: 1980
    The objective of this project is to evaluate the cost-effectiveness of an ambulatory drug utilization review (DUR) program with respect to a traditional care process, in terms of quality and economy of prescribing...
  22. ASSESSING RECALL ACCURACY FOR PRESCRIPTION MEDICATIONS
    Suzanne West; Fiscal Year: 1991
    b>Drug utilization review (DUR) programs are conducted to improve the effectiveness of drug use and are instituted in a majority of managed care institutions...
  23. REDUCING GERIATRIC DRUG THERAPY--TWO APPROACHES
    HELENE LIPTON; Fiscal Year: 1993
    ..outpatients by improving the quality of prescribing: 1) the application of a prospective computerized drug utilization review (DUR) system, and (2) ongoing clinical pharmacists' drug regimen reviews and consultations to ..
  24. MEDICATION USE IN ASSESSING AND IMPROVING ASTHMA CONTROL
    Tina Hartert; Fiscal Year: 2003
    ..events, and to develop a management scheme based on identification of medication use through a pharmacy-based drug utilization program...
  25. Impact of Medicaid Prescription Copayments in Patients with Schizophrenia
    Jalpa Doshi; Fiscal Year: 2009
    ..The rationale is that higher out-of-pocket payments would reduce unnecessary drug utilization and differential copayments would encourage use of less expensive drugs, leading to decreased expenditures...
  26. INFLUENCE OF TRIPLICATE POLICY ON NARCOTIC UTILIZATION
    Linda Simoni Wastila; Fiscal Year: 1992
    ..Although state and federal governments employ a variety of mechanisms to control drug utilization and attendant costs, triplicate, or Multiple Copy Prescription Programs (MCPPs), are an increasingly popular ..
  27. Impact of Medicare Drug Coverage on Non-Drug Spending
    MICHAEL FURUKAWA; Fiscal Year: 2004
    ..of how chronic illness affects the demand for medical care, which explains the tradeoff between the cost of drug utilization and the benefits of reduced risk of adverse medical events and lower functional disability...
  28. PSYCHOTROPIC DRUGS AND CARE OUTCOMES IN NURSING HOMES
    BARRY FOGEL; Fiscal Year: 1992
    ..psychotropic drug use will be obtained directly from facilities on all subjects at two timepoints; continuous drug utilization data for the entire six months will be derived from Medicaid claim data on at least half of the subjects...
  29. ALCOHOL & PRESCRIPTION DRUG INTERACTION IN THE ELDERLY
    Frank Ahern; Fiscal Year: 1991
    ..significance for the design and implementation of programs that include alcohol-related information in drug utilization review, drug surveillance and drug education activities in existing and several newly-emerging federal and ..
  30. Evaluating Drug Benefit Policy Changes in the Elderly
    Sebastian Schneeweiss; Fiscal Year: 2001
    ..Outcomes to be studied will include changes in drug utilization, clinical outcomes such as physician visits, hospitalizations, overall health care expenditures, long-term ..
  31. Medication Management Decisions in Schizophrenia
    Mark Olfson; Fiscal Year: 2003
    ..The results will inform quality improvement programs by identifying key modifiable determinants of the quality of medication management in the community treatment of schizophrenia. ..
  32. Effects of Mental Parity on High-Cost and Severely-Ill Individuals
    Haiden A Huskamp; Fiscal Year: 2011
    ..We will estimate a combination of two-part random-effects models for longitudinal data, latent class random-effects models, logistic regression models, Poisson regression models, and hazard models to address these aims. ..
  33. Improving Asthma Communication in Minority Families
    Arlene Butz; Fiscal Year: 2007
    ..abstract_text> ..
  34. Economics of Formulary Design and Mental Health Policy
    Haiden Huskamp; Fiscal Year: 2006
    ..Huskamp the training, mentoring, time and resources to develop the skills that will put her in a position to lead independent research on the economics of pharmaceutical treatment for mental illnesses. ..
  35. NEBULIZER INTERVENTION IN MINORITY CHILDREN WITH ASTHMA
    Arlene Butz; Fiscal Year: 2004
    ..Study findings will improve clinical care to this vulnerable population of children and will be if significant use to health care providers, researchers, insurers and policy makers. ..
  36. A+ Asthma Rural Partnership
    Arlene Butz; Fiscal Year: 2004
    ..The findings of this study will be important to clinicians, researchers, and health policy makers. ..
  37. Predicting Transitions Among Community-Dwelling Elders
    Ilene Zuckerman; Fiscal Year: 2008
    ....
  38. HOME NURSE INTERVENTION FOR IUDE INFANTS--3 YR FOLLOW UP
    Arlene Butz; Fiscal Year: 2002
    ..Data will be of significant use to researchers, health care providers, insurers and policy makers. ..
  39. Pathways into Services for Alcohol and Drug Disorders
    Mark J Edlund; Fiscal Year: 2010
    ..The results of the study will inform policy to increase rates of utilization of effective substance abuse services among those with substance use disorders. ..
  40. Decision Making in End-Stage Heart Failure
    Paul Hauptman; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  41. Impact of Medicaid Policy on cardiovascular drug use and clinical outcomes
    Michael A Fischer; Fiscal Year: 2010
    ..We will evaluate drug utilization outcomes and clinical outcomes in the overall Medicaid programs but will focus in particular on patient ..
  42. Cardiac-Related Mortality with Atypical Antipsychotics
    DEANNA KELLY; Fiscal Year: 2005
    ..This study is important as data on long-term health outcomes with atypical antipsychotics is lacking from the literature. ..
  43. Minimizing Antibiotic Resistance in Colorado (MARC)
    Ralph Gonzales; Fiscal Year: 2004
    ..pneumoniae infections in and outside the intervention communities. Specific Aim IIIC: Conduct a net-cost analysis of the different levels of community education. ..
  44. Impact of 3 Tier Drug Copays on Use and Spending
    Dominic Hodgkin; Fiscal Year: 2003
    ..abstract_text> ..
  45. Specialty Mental Health Care--Expanding Access in an HMO
    Dominic Hodgkin; Fiscal Year: 2003
    ..The results will inform health plan decision-makers and others as they make utilization management choices that may have a major impact on patients and enrollee populations overall. ..
  46. Improving Antibiotic Use in Acute Care Settings
    Ralph Gonzales; Fiscal Year: 2006
    ..Specific Aim 2: To evaluate the impact of a rapid diagnostic test for c-reactive protein on antibiotic use for adults with acute cough illness when added to a multidimensional intervention. ..
  47. The impact of the pneumococcal conjugate vaccine on pneumonia hospitalizations
    CARLOS GRIJALVA; Fiscal Year: 2008
    ..We propose the use of NIS and SID for the evaluation of the pneumococcal conjugate vaccination program, using an innovative approach. [unreadable] [unreadable] [unreadable] [unreadable]..
  48. The Balanced Budget Act of 1997 and Home Care for Cancer
    Meredith Kilgore; Fiscal Year: 2006
    ..Data generated from this study can be used to guide federal decision makers in formulating policies related to home health services for older cancer patients. ..
  49. The Role of Customization in Psychotropic Prescribing
    Dominic Hodgkin; Fiscal Year: 2009
    ....
  50. Comorbid Substance Abuse and Long-Term Health Outcomes in Schizophrenia
    DEANNA KELLY; Fiscal Year: 2008
    ..This will be an important step for improving the lives of people with schizophrenia. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  51. A PRESCRIPTION FOR ENHANCING RESIDENT QUALITY OF LIFE
    Ann Kolanowski; Fiscal Year: 2008
    ..This study holds promise for improving quality of life for nursing home residents with dementia by using theoretically based activities to respond to their needs. ..
  52. Vascular Depression and Function in Older Latinos
    HECTOR GONZALEZ; Fiscal Year: 2007
    ..abstract_text> ..
  53. Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma
    Adam Spanier; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  54. EFFECTIVENESS OF SWITCHING ANTIPSYCHOTIC MEDICATIONS
    Susan Essock; Fiscal Year: 2003
    ..abstract_text> ..
  55. Racial Differences in Geriatric Antidepressant Adherence
    HELEN KALES; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  56. Immune Thrombocytopenia and Low-Level Mercury Exposure
    Jodi Segal; Fiscal Year: 2006
    ..Segal with the necessary support for successful completion [unreadable] [unreadable] [unreadable]..
  57. Protective Influence of Residential Learning Communities
    SEAN MCCABE; Fiscal Year: 2006
    ..At each measurement point, participants will complete a set of measures that assess substance use behaviors and constructs addressed by RLCs. ..
  58. Mixed-Effects ZIP Models--Mental Health Service Research
    Robert Gibbons; Fiscal Year: 2004
    ..abstract_text> ..
  59. RISK FACTORS FOR PHENYTOIN TOXICITY
    Sean Hennessy; Fiscal Year: 2005
    ..abstract_text> ..
  60. Gene-Specific Responses to Exercise in Discordant Twins
    Paul Williams; Fiscal Year: 2007
    ..DNA samples will be shared with other institutions to cross-validate gene associations identified from training studies or other designs. ..
  61. Molecular Genetics of Inattention in Australia
    THEODORE CICERO; Fiscal Year: 2009
    ..This will be at a marked cost savings due to the employment of existing well-characterized samples and the long history of collaborative studies between investigators from Australia and the United States. ..
  62. ACUTE TOLERANCE IN ANESTHETIC ACTIONS AND INTERACTIONS
    Igor Kissin; Fiscal Year: 2001
    ....
  63. XYLITOL FOR ACUTE OTITIS MEDIA PROPHYLAXIS
    Louis Vernacchio; Fiscal Year: 2003
    ..A preliminary estimate of the effect size of xylitol treatment from the pilot RCT will suggest whether the effect if sufficiently large to warrant a large formal RCT to be proposed. ..
  64. Pediatric Severe Asthma: Role of Oxidant Stress and Alveolar Macrophage Function
    Anne Fitzpatrick; Fiscal Year: 2009
    ..This proposal will lay the foundation for further studies, and the mechanisms identified may ultimately be targeted in future interventional trials. ..