europe

Summary

Top Publications

  1. ncbi Estimates of cancer incidence and mortality in Europe in 2008
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Eur J Cancer 46:765-81. 2010
  2. ncbi Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project
    R M Conroy
    Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
    Eur Heart J 24:987-1003. 2003
  3. ncbi The structure of haplotype blocks in the human genome
    Stacey B Gabriel
    Whitehead MIT Center for Genome Research, Cambridge, MA 02139, USA
    Science 296:2225-9. 2002
  4. pmc Genes mirror geography within Europe
    John Novembre
    Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California Los Angeles, Los Angeles, California 90095, USA
    Nature 456:98-101. 2008
  5. ncbi Development of a common outcome data set for fall injury prevention trials: the Prevention of Falls Network Europe consensus
    Sarah E Lamb
    Warwick Emergency Care and Rehabilitation, University of Warwick, Coventry, UK
    J Am Geriatr Soc 53:1618-22. 2005
  6. ncbi Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
    Herman Goossens
    ESAC Management Team, Department of Microbiology, University of Antwerp, B 2610 Antwerp, Belgium
    Lancet 365:579-87. 2005
  7. ncbi Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment
    Harald Breivik
    University of Oslo, Faculty of Medicine, Faculty Division Rikshospitalet, Department of Anaesthesiology, Rikshospitalet University Hospital, Norway
    Eur J Pain 10:287-333. 2006
  8. ncbi General and abdominal adiposity and risk of death in Europe
    T Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    N Engl J Med 359:2105-20. 2008
  9. ncbi Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
    Christopher C Patterson
    Epidemiology Research Group, Centre for Public Health, Queen s University Belfast, Belfast, UK
    Lancet 373:2027-33. 2009
  10. pmc Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis
    Hajo Grundmann
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    PLoS Med 7:e1000215. 2010

Detail Information

Publications344 found, 100 shown here

  1. ncbi Estimates of cancer incidence and mortality in Europe in 2008
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Eur J Cancer 46:765-81. 2010
    ..country population estimates for 2008 to obtain an estimate of the numbers of cancer cases and deaths in Europe in 2008. There were an estimated 3.2 million new cases of cancer and 1.7 million deaths from cancer in 2008...
  2. ncbi Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project
    R M Conroy
    Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
    Eur Heart J 24:987-1003. 2003
    ..The SCORE project was initiated to develop a risk scoring system for use in the clinical management of cardiovascular risk in European clinical practice...
  3. ncbi The structure of haplotype blocks in the human genome
    Stacey B Gabriel
    Whitehead MIT Center for Genome Research, Cambridge, MA 02139, USA
    Science 296:2225-9. 2002
    ..haplotype patterns across 51 autosomal regions (spanning 13 megabases of the human genome) in samples from Africa, Europe, and Asia...
  4. pmc Genes mirror geography within Europe
    John Novembre
    Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California Los Angeles, Los Angeles, California 90095, USA
    Nature 456:98-101. 2008
    ..Europeans, we find a close correspondence between genetic and geographic distances; indeed, a geographical map of Europe arises naturally as an efficient two-dimensional summary of genetic variation in Europeans...
  5. ncbi Development of a common outcome data set for fall injury prevention trials: the Prevention of Falls Network Europe consensus
    Sarah E Lamb
    Warwick Emergency Care and Rehabilitation, University of Warwick, Coventry, UK
    J Am Geriatr Soc 53:1618-22. 2005
    ..Prevention of Falls Network Europe (ProFaNE) is a collaborative project to reduce the burden of fall injury in older people through excellence in ..
  6. ncbi Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
    Herman Goossens
    ESAC Management Team, Department of Microbiology, University of Antwerp, B 2610 Antwerp, Belgium
    Lancet 365:579-87. 2005
    ..Our aim was to assess outpatient use of antibiotics and the association with resistance...
  7. ncbi Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment
    Harald Breivik
    University of Oslo, Faculty of Medicine, Faculty Division Rikshospitalet, Department of Anaesthesiology, Rikshospitalet University Hospital, Norway
    Eur J Pain 10:287-333. 2006
    ..Forty percent had inadequate management of their pain. Interesting differences between countries were observed, possibly reflecting differences in cultural background and local traditions in managing chronic pain...
  8. ncbi General and abdominal adiposity and risk of death in Europe
    T Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    N Engl J Med 359:2105-20. 2008
    ....
  9. ncbi Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
    Christopher C Patterson
    Epidemiology Research Group, Centre for Public Health, Queen s University Belfast, Belfast, UK
    Lancet 373:2027-33. 2009
    ..We aimed to establish 15-year incidence trends for childhood type 1 diabetes in European centres, and thereby predict the future burden of childhood diabetes in Europe.
  10. pmc Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis
    Hajo Grundmann
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    PLoS Med 7:e1000215. 2010
    ..We aimed to map the geographic distribution of the dominant clones that cause invasive infections in Europe.
  11. ncbi Climate change and infectious diseases in Europe
    Jan C Semenza
    Section Future Threats and Determinants, Unit of Scientific Advice, European Centre for Disease Prevention and Control, Stockholm, Sweden
    Lancet Infect Dis 9:365-75. 2009
    ..acquired through various routes (arthropod vector, rodent, water, food, and air) in view of a changing climate in Europe. Based on an extensive review of published work and expert workshops, we present an assessment of the infectious ..
  12. ncbi Comparative phylogeography and postglacial colonization routes in Europe
    P Taberlet
    Laboratoire de Biologie des populations d Altitude, CNRS UMR 5553, Universite Joseph Fourier, Grenoble, France
    Mol Ecol 7:453-64. 1998
    The Quaternary cold periods in Europe are thought to have heavily influenced the amount and distribution of intraspecific genetic variation in both animals and plants...
  13. pmc West Nile fever--a reemerging mosquito-borne viral disease in Europe
    Z Hubalek
    Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic
    Emerg Infect Dis 5:643-50. 1999
    West Nile virus causes sporadic cases and outbreaks of human and equine disease in Europe (western Mediterranean and southern Russia in 1962-64, Belarus and Ukraine in the 1970s and 1980s, Romania in 1996-97, Czechland in 1997, and Italy ..
  14. pmc Climate change threats to plant diversity in Europe
    Wilfried Thuiller
    Centre d Ecologie Fonctionnelle et Evolutive, Centre National de la Recherche Scientifique Unité Mixte de Recherche 5175, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    Proc Natl Acad Sci U S A 102:8245-50. 2005
    ..turnover per pixel proved to be highly variable across scenarios (27-42% and 45-63% respectively, averaged over Europe) and across regions (2.5-86% and 17-86%, averaged over scenarios)...
  15. ncbi The public health effect of economic crises and alternative policy responses in Europe: an empirical analysis
    David Stuckler
    Department of Sociology, Oxford University, Oxford, UK
    Lancet 374:315-23. 2009
    ..We investigated how economic changes have affected mortality rates over the past three decades and identified how governments might reduce adverse effects...
  16. ncbi Estimates of the cancer incidence and mortality in Europe in 2006
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Ann Oncol 18:581-92. 2007
    Monitoring the evolution of the cancer burden in Europe is of great value. Estimates of the cancer burden in Europe have been published for 2004 and estimates are now being presented for cancer incidence and mortality in Europe for 2006.
  17. ncbi European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection
    E Riboli
    Unit of Nutrition and Cancer, International Agency for Research on Cancer IARC WHO, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Public Health Nutr 5:1113-24. 2002
    ..The present paper provides a description of the EPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort...
  18. ncbi A historical review of managed honey bee populations in Europe and the United States and the factors that may affect them
    Dennis vanEngelsdorp
    Department of Entomology, The Pennsylvania State University, 501 ASI Bldg, University Park, PA 16802, USA
    J Invertebr Pathol 103:S80-95. 2010
    ..honey bee populations have not been increasing in all parts of the world, and have declined in many nations in Europe and in North America...
  19. ncbi West Nile virus: an overview of its spread in Europe and the Mediterranean basin in contrast to its spread in the Americas
    H G Zeller
    Institut Pasteur, National Reference Center for Arboviruses, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France
    Eur J Clin Microbiol Infect Dis 23:147-56. 2004
    ..It is widely distributed in Africa, the Middle East, Asia, and southern Europe and was recently introduced to North America. Birds are involved in the cycle of transmission as amplifying hosts...
  20. ncbi Recent cancer survival in Europe: a 2000-02 period analysis of EUROCARE-4 data
    Arduino Verdecchia
    National Centre for Epidemiology, Health Surveillance and Promotion, Istituto Superiore di Sanita, Rome, Italy
    Lancet Oncol 8:784-96. 2007
    ..cancer registries to estimate recent survival by country and cancer site, and to assess survival changes in Europe. We also compared our findings with data on cancer survival in the USA from the US SEER (Surveillance, ..
  21. ncbi Transmission of drug-resistant HIV-1 is stabilizing in Europe
    Jurgen Vercauteren
    Katholieke Universiteit Leuven, Leuven, Belgium
    J Infect Dis 200:1503-8. 2009
    ..04) and in NNRTI resistance after an initial increase (P = .02). We found that TDR appears to be stabilizing in Europe, consistent with recent reports of decreasing drug resistance and improved viral suppression in patients treated ..
  22. ncbi Socioeconomic inequalities in health in 22 European countries
    Johan P Mackenbach
    Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
    N Engl J Med 358:2468-81. 2008
    Comparisons among countries can help to identify opportunities for the reduction of inequalities in health. We compared the magnitude of inequalities in mortality and self-assessed health among 22 countries in all parts of Europe.
  23. ncbi Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillanc
    D J Diekema
    Medical Microbiology Division, Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Clin Infect Dis 32:S114-32. 2001
    ..species (CoNS) were referred by SENTRY-participating hospitals in the United States, Canada, Latin America, Europe, and the Western Pacific region. S...
  24. ncbi Genetic structure of human populations
    Noah A Rosenberg
    Molecular and Computational Biology, 1042 West 36th Place DRB 289, University of Southern California, Los Angeles, CA 90089, USA
    Science 298:2381-5. 2002
    ..General agreement of genetic and predefined populations suggests that self-reported ancestry can facilitate assessments of epidemiological risks but does not obviate the need to use genetic information in genetic association studies...
  25. ncbi Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East
    Robert S Lanciotti
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Fort Collins, Colorado 80521, USA
    Virology 298:96-105. 2002
    ..Lineage 1 WN viruses have been isolated from the northeastern United States, Europe, Israel, Africa, India, Russia, and Australia...
  26. ncbi Genetic discontinuity between local hunter-gatherers and central Europe's first farmers
    B Bramanti
    Institute for Anthropology, University of Mainz, Mainz, Germany
    Science 326:137-40. 2009
    ..the domestication of animals and crops in the Near East some 11,000 years ago, farming had reached much of central Europe by 7500 years before the present...
  27. ncbi Size and burden of mental disorders in Europe--a critical review and appraisal of 27 studies
    Hans Ulrich Wittchen
    Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
    Eur Neuropsychopharmacol 15:357-76. 2005
    ..These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations...
  28. ncbi Culicoides and the emergence of bluetongue virus in northern Europe
    Simon Carpenter
    Vector Borne Diseases Programme, Institute for Animal Health, Woking, Surrey, GU24 0BN, UK
    Trends Microbiol 17:172-8. 2009
    In June 2006, bluetongue virus, an arboviral pathogen of ruminants, appeared in northern Europe for the first time, successfully overwintered and subsequently caused substantial losses to the farming sector in 2007 and 2008...
  29. ncbi Prevalence of overweight among children in Europe
    T Lobstein
    International Obesity Task Force, London, UK
    Obes Rev 4:195-200. 2003
    ..The present paper reports the prevalence data from 21 surveys in Europe using a single, internationally accepted definition of overweight in childhood, allowing direct comparisons to be ..
  30. ncbi Emerging arthropod-borne diseases of companion animals in Europe
    Frederic Beugnet
    Meria Animal Health, 69007, Lyon, France
    Vet Parasitol 163:298-305. 2009
    ..The frequency of some vector-borne diseases of pets is increasing in Europe, i.e...
  31. ncbi Europe-wide reduction in primary productivity caused by the heat and drought in 2003
    Ph Ciais
    Laboratoire des Sciences du Climat et de l Environnement, LSCE, F 91191, Gif sur Yvette, France
    Nature 437:529-33. 2005
    ..We estimate a 30 per cent reduction in gross primary productivity over Europe, which resulted in a strong anomalous net source of carbon dioxide (0...
  32. pmc Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls
    Ron A M Fouchier
    Dept of Virology, Erasmus Medical Center, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    J Virol 79:2814-22. 2005
    ..We propose that sequence analyses of HA and NA genes of influenza A viruses be used for the rapid identification of existing and novel HA and NA subtypes...
  33. pmc PDBe: Protein Data Bank in Europe
    S Velankar
    Protein Databank in Europe, EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 38:D308-17. 2010
    The Protein Data Bank in Europe (PDBe) (http://www.ebi.ac...
  34. ncbi Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group
    A Mocroft
    Royal Free Centre for HIV Medicine and Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, UK
    Lancet 352:1725-30. 1998
    ..We examined the change in these mortality rates of HIV-1-infected patients across Europe during 1994-98, and assessed the extent to which changes can be explained by the use of new therapeutic regimens.
  35. ncbi A systematic review of brain injury epidemiology in Europe
    F Tagliaferri
    WHO Neurotrauma Collaborating Centre, M Bufalini Hospital, Cesena, Italy
    Acta Neurochir (Wien) 148:255-68; discussion 268. 2006
    ..Thus, we describe epidemiological factors from European studies largely published in the last 20 years...
  36. ncbi Allergenic pollen and pollen allergy in Europe
    G D'Amato
    Division of Respiratory and Allergic Diseases, Department of Chest Diseases, High Speciality Hospital A Cardarelli Napoli, Italy
    Allergy 62:976-90. 2007
    ..Aerobiological and allergological studies show that the pollen map of Europe is changing also as a result of cultural factors (for example, importation of plants such as birch and cypress for ..
  37. ncbi Contemporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY Antimicrobial Surveillance Program (1998-2004)
    Gary J Moet
    JMI Laboratories, North Liberty, IA 52317, USA
    Diagn Microbiol Infect Dis 57:7-13. 2007
    ..9%) compared with Latin America (29.4%) and Europe (22.8%). Vancomycin-resistant Enterococcus spp. increased in Europe (4.1%) and North America (6...
  38. pmc Characterization of a novel flavivirus from mosquitoes in northern europe that is related to mosquito-borne flaviviruses of the tropics
    Eili Huhtamo
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Virol 83:9532-40. 2009
    ..flavivirus was isolated from mosquitoes in Finland, representing the first mosquito-borne flavivirus from Northern Europe. The isolate, designated Lammi virus (LAMV), was antigenically cross-reactive with other flaviviruses and ..
  39. ncbi Hantavirus infections in Europe
    Olli Vapalahti
    Division of Microbiology and Epidemiology, Faculty of Veterinary Medicine, University of Helsinki and HUCH Laboratory Diagnostics, Helsinki University Central Hospital, Finland
    Lancet Infect Dis 3:653-61. 2003
    ..In Europe. Puumala causes a generally mild disease, nephropathia epidemica, which presents most commonly with fever, ..
  40. ncbi Sequence typing reveals extensive strain diversity of the Lyme borreliosis agents Borrelia burgdorferi in North America and Borrelia afzelii in Europe
    Jonas Bunikis
    Department of Microbiology, B240 Medical Sciences I, University of California Irvine, Irvine, CA 92697 4025, USA
    Microbiology 150:1741-55. 2004
    ..diversity previously reported from larger areas of the north-eastern United States and central and northern Europe. Although ospC alleles of both species had higher nucleotide diversity than other loci, the ospC locus showed ..
  41. ncbi Association of Borrelia afzelii with rodents in Europe
    K Hanincová
    Department of Infectious Disease Epidemiology, Imperial College of Science, Technology and Medicine, Norfolk Place, London W2 1PG, UK
    Parasitology 126:11-20. 2003
    ..afzelii is specifically maintained by European rodents, validating the concept of host-association of B. burgdorferi s.l...
  42. pmc Risk factors for multidrug resistant tuberculosis in Europe: a systematic review
    A Faustini
    Department of Epidemiology, RME, 00198 Rome, Italy
    Thorax 61:158-63. 2006
    ..The aim of this report is to determine risk factors for MDR-TB in Europe.
  43. pmc Excess winter mortality in Europe: a cross country analysis identifying key risk factors
    J D Healy
    Department of Environmental Studies, University College Dublin, Richview Campus, Dublin 14, Ireland
    J Epidemiol Community Health 57:784-9. 2003
    ..Comparatively less research exists on excess winter deaths in southern Europe. Multiple time series data on a variety of risk factors are analysed against seasonal-mortality patterns in 14 ..
  44. ncbi Cost of depression in Europe
    Patrik Sobocki
    Medical Management Centre, Department of Learning Informatics Management and Ethics, Karolinska Institutet, Stockholm, Sweden
    J Ment Health Policy Econ 9:87-98. 2006
    ..WHO data suggests that depression causes 6% of the burden of all diseases in Europe in terms of disability adjusted life years (DALYs)...
  45. ncbi Walking, cycling, and obesity rates in Europe, North America, and Australia
    David R Bassett
    University of Tennessee Obesity Research Center, The University of Tennessee, Knoxville, TN 37996, USA
    J Phys Act Health 5:795-814. 2008
    ..This study was designed to examine the relationship between active transportation (defined as the percentage of trips taken by walking, bicycling, and public transit) and obesity rates (BMI > or = 30 kg . m-2) in different countries...
  46. ncbi Stroke incidence and prevalence in Europe: a review of available data
    T Truelsen
    World Health Organization, Geneva, Switzerland
    Eur J Neurol 13:581-98. 2006
    ..A standardized protocol for stroke surveillance is recommended...
  47. pmc eHealth trends in Europe 2005-2007: a population-based survey
    Per Egil Kummervold
    Norwegian Centre for Telemedicine, University Hospital of North Norway, PO Box 35, N 9038 Tromsø, Norway
    J Med Internet Res 10:e42. 2008
    ..People are using the Internet for various health-related purposes. It is important to monitor such use as it may have an impact on the individual's health and behavior, patient-practitioner roles, and on general health care provision...
  48. pmc European bat Lyssavirus transmission among cats, Europe
    Laurent Dacheux
    Institut Pasteur, Paris, France
    Emerg Infect Dis 15:280-4. 2009
    ..We identified 2 cases of European bat lyssavirus subtype 1 transmission to domestic carnivores (cats) in France. Bat-to-cat transmission is suspected. Low amounts of virus antigen in cat brain made diagnosis difficult...
  49. ncbi Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe
    Jonathan A Otter
    Department of Infection, King s College London and St Thomas Hospital, London, UK
    Lancet Infect Dis 10:227-39. 2010
    ..Although data are limited, the prevalence of community-associated MRSA in Europe seems to be low but is increasing...
  50. ncbi The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study
    Francoise Forette
    Department of Geriatrics, Hopital Broca, CHU Cochin, University of Paris V, 54 56 Rue Pascal, 75013 Paris, France
    Arch Intern Med 162:2046-52. 2002
    After the double-blind, placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial ended in February 1997, randomized patients were offered active study medication for a further period of observation.
  51. pmc Incidence of amyotrophic lateral sclerosis in Europe
    Giancarlo Logroscino
    Department of Neurology and Psychiatry, Piazza Giulio Cesare, Policlinico, 70121 Bari, Italy
    J Neurol Neurosurg Psychiatry 81:385-90. 2010
    ..To address these issues, the authors undertook a pooled analysis of European population based ALS registries...
  52. ncbi Health impacts of long-term exposure to disinfection by-products in drinking water in Europe: HIWATE
    Mark J Nieuwenhuijsen
    Centre for research in Environmental, Epidemiology CREAL, Parc de Recerca Biomédical de Barcelona PRBB, Barcelona, Spain
    J Water Health 7:185-207. 2009
    ..The outcome will be improved risk assessment and better information for risk management. The work is divided into different topics (exposure assessment, epidemiology, risk assessment and management) and studies...
  53. ncbi Epidemiology of candidaemia in Europe: results of 28-month European Confederation of Medical Mycology (ECMM) hospital-based surveillance study
    A M Tortorano
    Istituto di Igiene e Medicina Preventiva, Universita degli Studi, IRCCS Ospedale Maggiore, Via F Sforza 35, 20122 Milan, Italy
    Eur J Clin Microbiol Infect Dis 23:317-22. 2004
    In order to update the epidemiological and mycological profile of candidaemia in Europe, the European Confederation of Medical Mycology conducted a prospective, sequential, hospital population-based study from September 1997 to December ..
  54. pmc Ancient DNA, pig domestication, and the spread of the Neolithic into Europe
    Greger Larson
    Department of Zoology, Henry Wellcome Ancient Biomolecules Centre, South Parks Road, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 104:15276-81. 2007
    The Neolithic Revolution began 11,000 years ago in the Near East and preceded a westward migration into Europe of distinctive cultural groups and their agricultural economies, including domesticated animals and plants...
  55. ncbi Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality
    Alexander T Cohen
    Vascular Medicine, Department of Surgery, King s College Hospital, London, SE5 9RS, UK
    Thromb Haemost 98:756-64. 2007
    ..Given the availability of effective VTE prophylaxis, many of these events and deaths could have been prevented. These results have important implications for the allocation of healthcare resources...
  56. ncbi Confounding and effect modification in the short-term effects of ambient particles on total mortality: results from 29 European cities within the APHEA2 project
    K Katsouyanni
    Department of Hygiene and Epidemiology, University of Athens Medical School, 75 Mikras Asias Street, 115 27 Athens, Greece
    Epidemiology 12:521-31. 2001
    ..Furthermore, they show that the heterogeneity found in the effect parameters among cities reflects real effect modification, which is explained by specific city characteristics...
  57. ncbi Ecology of yeasts in plant-bumblebee mutualism in Central Europe
    Michael Brysch-Herzberg
    Department of Biology, Philipps University Marburg, 35043 Marburg, Germany
    FEMS Microbiol Ecol 50:87-100. 2004
    ....
  58. ncbi Reemergence of the HIV epidemic among men who have sex with men in North America, Western Europe, and Australia, 1996-2005
    Patrick S Sullivan
    Department of Epidemiology, Emory University, Rollins School of Public Health, Atlanta, GA 30322, USA
    Ann Epidemiol 19:423-31. 2009
    ....
  59. ncbi Health-economic burden of obesity in Europe
    Falk Müller-Riemenschneider
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    Eur J Epidemiol 23:499-509. 2008
    ..There remains a great need for prospective and standardised studies to provide more accurate estimates of costs for all European countries...
  60. ncbi Welfare state regimes and differences in self-perceived health in Europe: a multilevel analysis
    Terje Andreas Eikemo
    Department of Sociology and Political Science, Norwegian University of Science and Technology, Trondheim, Norway
    Soc Sci Med 66:2281-95. 2008
    ..People in countries with Scandinavian and Anglo-Saxon welfare regimes were observed to have better self-perceived general health in comparison to Southern and East European welfare regimes...
  61. ncbi Cost of disorders of the brain in Europe
    Patrik Andlin-Sobocki
    Stockholm Health Economics, Stockholm, Sweden
    Eur J Neurol 12:1-27. 2005
  62. ncbi The 2006 outbreak of bluetongue in northern Europe--the entomological perspective
    R Meiswinkel
    Central Veterinary Institute of Wageningen UR, P O Box 65, 8200 AB Lelystad, The Netherlands
    Prev Vet Med 87:55-63. 2008
    After bluetongue (BT) appeared in northern Europe in August 2006 entomological studies were implemented in all five affected Member States (MSs) to establish which species of Culicoides had acted as vectors...
  63. ncbi Stage at diagnosis is a key explanation of differences in breast cancer survival across Europe
    Milena Sant
    Epidemiology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, I 20133 Milan, Italy
    Int J Cancer 106:416-22. 2003
    ..There was considerable variation across Europe in relative survival within each disease stage, but this was least marked for early node-negative tumours...
  64. ncbi Characteristics of binge drinkers in Europe
    E Kuntsche
    Research Department, Swiss Institute for the Prevention of Alcohol and Drug Problems, PO Box 870, Lausanne 1001, Switzerland
    Soc Sci Med 59:113-27. 2004
    ..the predominant adult and adolescent drinking culture with more binge drinking in the northern and middle parts of Europe compared to the southern parts...
  65. pmc Bluetongue in Europe: past, present and future
    Anthony J Wilson
    Institute for Animal Health Pirbright Laboratory, Pirbright, Woking, Surrey GU24 0NF, UK
    Philos Trans R Soc Lond B Biol Sci 364:2669-81. 2009
    The recent arrival in Northern and Western (NW) Europe of bluetongue virus (BTV), which causes the ruminant disease 'bluetongue', has raised the profile of this vector-borne ruminant disease and sparked discussions on the reasons for its ..
  66. pmc A European study on the relationship between antimicrobial use and antimicrobial resistance
    Stef L A M Bronzwaer
    National Institute of Public Health and the Environment, Department of Infectious Disease Epidemiology, Postbak 75, PO Box 1, Antonie van Leeuwenhoeklaan 9, 3720 BA Bilthoven, The Netherlands
    Emerg Infect Dis 8:278-82. 2002
    In Europe, antimicrobial resistance has been monitored since 1998 by the European Antimicrobial Resistance Surveillance System (EARSS)...
  67. ncbi The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis
    J G F Cleland
    Department of Cardiology, University of Hull, Castle Hill Hospital, Castle Road, Kingston upon Hull HU16 5JQ UK
    Eur Heart J 24:442-63. 2003
    ..Accordingly, the EuroHeart Failure survey was conducted to ascertain if appropriate tests were being performed with which to confirm or refute a diagnosis of heart failure and how this influenced subsequent management...
  68. ncbi Potentially inappropriate medication use among elderly home care patients in Europe
    Daniela Fialova
    Department of Geriatrics and Gerontology, 1st Medical Faculty, Charles University, Prague, Czech Republic
    JAMA 293:1348-58. 2005
    ..In contrast, in Europe little information is available about potentially inappropriate medication use and is based on small studies with ..
  69. pmc Epidemiology of gastro-oesophageal reflux disease: a systematic review
    J Dent
    Department of Gastroenterology, Hepatology, and General Medicine, Level 7, North Wing, North Terrace, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Gut 54:710-7. 2005
    ..The small number of studies eligible for inclusion in this review highlights the need for global consensus on a symptom based definition of GORD...
  70. pmc The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia
    Sophie Rogers
    Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Vic, Australia
    Ophthalmology 117:313-9.e1. 2010
    To summarize the prevalence of retinal vein occlusion (RVO) from studies in the United States, Europe, Asia, and Australia.
  71. ncbi Does informal care from children to their elderly parents substitute for formal care in Europe?
    Eric Bonsang
    CREPP, HEC ULg Management School, Bd du Rectorat B31, 7, 4000 Liege, Belgium
    J Health Econ 28:143-54. 2009
    This paper analyzes the impact of informal care by adult children on the use of long-term care among the elderly in Europe and the effect of the level of the parent's disability on this relationship...
  72. ncbi High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study
    L Prompers
    Department of Internal Medicine, University Hospital Maastricht, P Debeyelaan 25, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
    Diabetologia 50:18-25. 2007
    ..The aim of this study was to investigate the characteristics of diabetic patients with a foot ulcer in 14 European hospitals in ten countries...
  73. ncbi Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy
    Wim J Kleijer
    Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands
    DNA Repair (Amst) 7:744-50. 2008
    Laboratory diagnosis for DNA repair diseases has been performed in western Europe from the early seventies for xeroderma pigmentosum (XP) and from the mid-eighties for Cockayne syndrome (CS) and trichothiodystrophy (TTD)...
  74. ncbi Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    David A Goodkin
    Amgen Inc, Thousand Oaks, California, USA
    J Am Soc Nephrol 14:3270-7. 2003
    ..The crude 1-yr mortality rates were 6.6% in Japan, 15.6% in Europe, and 21.7% in the US...
  75. ncbi Practice guidelines of the European Society of Hypertension for clinic, ambulatory and self blood pressure measurement
    Eoin O'Brien
    Beaumont Hospital and Department of Clinical Pharmacology, Royal College of Surgeons, Beaumont Road, Dublin 9, Ireland
    J Hypertens 23:697-701. 2005
  76. pmc Influenza activity in Europe during eight seasons (1999-2007): an evaluation of the indicators used to measure activity and an assessment of the timing, length and course of peak activity (spread) across Europe
    John Paget
    Netherlands Institute for Health Services Research NIVEL, PO Box 1568, 3500BN, Utrecht, The Netherlands
    BMC Infect Dis 7:141. 2007
    ..The EISS dataset was used to characterise important epidemiological features of influenza activity in Europe during eight winters (1999-2007)...
  77. ncbi Impact of COPD in North America and Europe in 2000: subjects' perspective of Confronting COPD International Survey
    S Rennard
    University of Nebraska, Pulmonary and Critical Care Medicine Section, Omaha 68198 5125, USA
    Eur Respir J 20:799-805. 2002
    ..The mean age of the subjects was 63.3 yrs and 44.2% were female. Subjects with COPD in North America and Europe appear to underestimate their morbidity, as shown by the high proportion of subjects with limitations to their ..
  78. ncbi Effectiveness of school-based interventions in Europe to promote healthy nutrition in children and adolescents: systematic review of published and 'grey' literature
    Eveline Van Cauwenberghe
    Department of Movement and Sport Sciences, Ghent University, 9000 Ghent, Belgium
    Br J Nutr 103:781-97. 2010
    ..Evidence for effectiveness on anthropometrical obesity-related measures is lacking...
  79. ncbi A brief overview of photodynamic therapy in Europe
    D Mitton
    Department of Surgery, K Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom
    Photodiagnosis Photodyn Ther 5:103-11. 2008
    ..We briefly review and highlight some of the landmarks of the development of clinical PDT in Europe.
  80. ncbi Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United States and Europe
    Antonio Alberto Lopes
    Department of Medicine, Federal University of Bahia, Brazil
    Kidney Int 62:199-207. 2002
    ..We investigated whether risk of mortality and rate of hospitalization may be predicted from physician-diagnosed depression and patients' self-reports of depressive symptoms...
  81. ncbi Requirements for DXA for the management of osteoporosis in Europe
    J A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX, UK
    Osteoporos Int 16:229-38. 2005
    ..The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen...
  82. pmc Suicide methods in Europe: a gender-specific analysis of countries participating in the "European Alliance Against Depression"
    A Varnik
    Estonian Swedish Mental Health and Suicidology Institute, Estonian Centre of Behavioural and Health Sciences, Oie 39, Tallinn 11615, Estonia
    J Epidemiol Community Health 62:545-51. 2008
    To identify the most frequent gender-specific suicide methods in Europe.
  83. ncbi Glacial refugia: hotspots but not melting pots of genetic diversity
    Remy J Petit
    Institut National de la Recherche Agronomique, UMR Biodiversité, Génes et Ecosystémes, F 33612 Cestas, France
    Science 300:1563-5. 2003
    ..However, the genetically most diverse populations were not located in the south but at intermediate latitudes, a likely consequence of the admixture of divergent lineages colonizing the continent from separate refugia...
  84. pmc Antimicrobial drug use and resistance in Europe
    Nienke van de Sande-Bruinsma
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Emerg Infect Dis 14:1722-30. 2008
    ..Ecologic studies based on routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial drug consumption at a national level in Europe.
  85. ncbi Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe
    R Canton
    Servicio de Microbiologia, Hospital Universitario Ramon y Cajal, Madrid, Spain
    Clin Microbiol Infect 14:144-53. 2008
    ..The first types described were derivatives of the TEM-1, TEM-2 and SHV-1 enzymes during the 1980s in Europe, mainly in Klebsiella pneumoniae associated with nosocomial outbreaks...
  86. ncbi EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary
    Milena Sant
    Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
    Eur J Cancer 45:931-91. 2009
    ..For all cancers, 5-year survival conditional to surviving 1-year was higher and varied less with region, than the overall relative survival...
  87. ncbi Long-term survival expectations of cancer patients in Europe in 2000-2002
    Hermann Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Eur J Cancer 45:1028-41. 2009
    ..For most cancer sites, survival in countries from Northern Europe, Central Europe and Southern Europe was substantially higher than in the United Kingdom and Ireland and in ..
  88. ncbi Distribution and determinants of house dust mite allergens in Europe: the European Community Respiratory Health Survey II
    Jan Paul Zock
    Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain
    J Allergy Clin Immunol 118:682-90. 2006
    ....
  89. ncbi Antimicrobial susceptibility among organisms from the Asia/Pacific Rim, Europe and Latin and North America collected as part of TEST and the in vitro activity of tigecycline
    Ralf Rene Reinert
    Institute for Medical Microbiology, National Reference Centre for Streptococci, Aachen, Germany
    J Antimicrob Chemother 60:1018-29. 2007
    To describe antimicrobial susceptibility among bacterial isolates associated with hospital infections collected from 266 centres in Asia/Pacific Rim (n = 1,947), North America (n = 24,283), Latin America (n = 1,957) and Europe (n = 8,796).
  90. ncbi Correlation between genetic and geographic structure in Europe
    Oscar Lao
    Department of Forensic Molecular Biology, Erasmus University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands
    Curr Biol 18:1241-8. 2008
    ..Previous population genetic analyses with autosomal markers in Europe either had a wide geographic but narrow genomic coverage [1, 2], or vice versa [3-6]...
  91. ncbi Population level of unmet need for mental healthcare in Europe
    Jordi Alonso
    Health Services Research Unit, Institut Municipal d Investigacio Medica, Carrer del Doctor Aiguader, 88 E 08003 Barcelona, Spain
    Br J Psychiatry 190:299-306. 2007
    ..The high prevalence of mental disorders has fuelled controversy about the need for mental health services...
  92. ncbi Assisted reproductive technology in Europe, 2004: results generated from European registers by ESHRE
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 23:756-71. 2008
    ..European results of assisted reproductive techniques from treatments initiated during 2004 are presented in this eighth report...
  93. ncbi Impact of osteoporosis treatment adherence on fracture rates in North America and Europe
    Ethel S Siris
    Toni Stabile Osteoporosis Center, Department of Medicine, Columbia University Medical Center, New York, New York 10032, USA
    Am J Med 122:S3-13. 2009
    ....
  94. pmc Spread of vector-borne diseases and neglect of Leishmaniasis, Europe
    Jean Claude Dujardin
    Instituut voor Tropische Geneeskunde, Antwerp, Belgium
    Emerg Infect Dis 14:1013-8. 2008
    The risk for reintroduction of some exotic vector-borne diseases in Europe has become a hot topic, while the reality of others is neglected at the public health policy level...
  95. ncbi Physical activity levels and patterns of 9- and 15-yr-old European children
    Chris J Riddoch
    Department of Exercise and Health Sciences, University of Bristol, Bristol, UK
    Med Sci Sports Exerc 36:86-92. 2004
    ..Very limited physical activity data exist that have been collected from representative samples of children and even fewer data collected where physical activity has been measured using objective methods...
  96. ncbi Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program
    J Gabert
    Department of Hematology Biology, Institut Paoli Calmettes, France
    Leukemia 17:2318-57. 2003
    ..for TaqMan-based real-time quantitative PCR (RQ-PCR) analysis of the main leukemia-associated FGs within the Europe Against Cancer (EAC) program...
  97. ncbi Candidaemia in Europe: epidemiology and resistance
    Anna Maria Tortorano
    Istituto di Igiene e Medicina Preventiva, Universita degli Studi di Milano, Via Pascal 36, 20133 Milan, Italy
    Int J Antimicrob Agents 27:359-66. 2006
    ..From an analysis of multi-institutional surveys of Candida BSIs performed in Europe, including the large prospective survey by the European Confederation of Medical Mycology (2089 episodes from ..
  98. ncbi The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. The Euro Heart Survey on diabetes and the heart
    Małgorzata Bartnik
    Department of Cardiology, Karolinska University Hospital, Solna, Stockholm, Sweden
    Eur Heart J 25:1880-90. 2004
    ..The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD)...
  99. ncbi Biodiversity differences between managed and unmanaged forests: meta-analysis of species richness in Europe
    Yoan Paillet
    Cemagref, UR EFNO, Domaine des Barres, F 45290 Nogent sur Vernisson, France
    Conserv Biol 24:101-12. 2010
    ..present pressures on forest resources have led to a drastic decrease in the surface area of unmanaged forests in Europe. Changes in forest structure, composition, and dynamics inevitably lead to changes in the biodiversity of forest-..
  100. pmc Biodiversity of pig breeds from China and Europe estimated from pooled DNA samples: differences in microsatellite variation between two areas of domestication
    Hendrik Jan Megens
    Wageningen University, Animal Breeding and Genomics Centre, PO Box 338, 6700AH, Wageningen, The Netherlands
    Genet Sel Evol 40:103-28. 2008
    ..Comparing correlations between genetic distance and heterozygosity revealed that China and Europe represent different domestication or breed formation processes...
  101. pmc The introduction history of invasive garden ants in Europe: integrating genetic, chemical and behavioural approaches
    Line V Ugelvig
    Centre for Social Evolution, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmark
    BMC Biol 6:11. 2008
    ..In this study, we aim to reconstruct the invasion history of this ant in Europe analysing 14 populations with three complementary approaches: genetic microsatellite analysis, chemical analysis ..

Research Grants74

  1. CFI Pathogen Inactivation Technology
    Trevor P Castor; Fiscal Year: 2010
    ..This orthogonal approach is consistent with the regulatory authorities in Europe and the US that require a minimum of two pathogen inactivation technologies, which work by different mechanisms of ..
  2. A unique approach to identify markers for congenital syphilis and neurosyphilis
    Nikhat Parveen; Fiscal Year: 2010
    ..in the Western countries but they remain a problem in underdeveloped countries of Africa, Central Asia and Eastern Europe. Congenital syphilis is devastating and can result in stillbirths, abortions, low birth weights or premature ..
  3. Latin American Center for Malaria Research and Control
    SOCRATES HERRERA VALENCIA; Fiscal Year: 2013
    ..scientists from other endemic countries such as Ecuador and Brazil, as well as from United State (USA) and Europe. The ICEMR research activities have been divided into three closely inter-related projects as follows: Project 1 ..
  4. Development of Vaccines against Clostridium difficile Infection
    SAUL R TZIPORI; Fiscal Year: 2013
    ..difficile infection (CDI) has increased significantly in both North America and Europe, causing lengthy hospitalization, substantial morbidity and mortality...
  5. Metabolic Adapation and Control of Lactation in Humans
    Morey W Haymond; Fiscal Year: 2010
    ..S. and Western Europe. Human milk is universally accepted as the ideal food for infants and breastfeeding has real and potential ..
  6. Investigation of Occupational Exposure to and Infection by MRSA in Rural Iowa
    Tara Smith; Fiscal Year: 2012
    ..Reports from Europe and Canada have reported another potential MRSA risk group: individuals in contact with livestock and poultry...
  7. Development of a Pediatric Mylelodysplastic Syndrome Patient Registry
    DAVID A contact WILLIAMS; Fiscal Year: 2010
    ..Charlotte Niemeyer, to learn from their experience setting up a similar registry in Europe that has now been in existence for 10 years...
  8. Severe H1N1 Influenza Infection During Pregnancy: Pathophysiologic Mechanisms
    Mark Phillippe; Fiscal Year: 2010
    ..During May and early June, this novel H1N1 infection spread to multiple other countries in the Americas, Europe, Asia, the Middle East, and the Pacific basin, resulting in the World Health Organization (WHO) increasing its ..
  9. Impact of smoking on immune response and arthritis in humanized mice
    Veena Taneja; Fiscal Year: 2011
    ..These studies may rationalize the differences observed in human study cohorts from Europe and USA...
  10. A novel allele influencing HIV infection among injection drug users
    Xiao Fang Yu; Fiscal Year: 2012
    ..HIV infection in injection drug users (IDUs) also represents a growing problem in southeast Asia and eastern Europe: In China, IDUs account for more than 50% of HIV-1 infections...
  11. The influence of selenium on biomarkers of prostate cancer risk
    KARAM E EL-BAYOUMY; Fiscal Year: 2012
    ..SM is currently being used in a major clinical trial in the USA (SELECT) and SY is employed in the trial in Europe (PRECISE);the results will be known in 2013 and beyond...
  12. Mechanisms for Cardiovascular Effects of air pollutants: Effect of Age and Sex
    BRITT HOLMEN; Fiscal Year: 2010
    ..S. and Europe. Biodiesel is typically blended into conventional diesel fuel, and emission testing has shown that biodiesel ..
  13. OLFACTORY RECEPTOR COPY NUMBER ASSOCIATION WITH AGE AT ONSET OF ALZHEIMER DISEASE
    Kinga Szigeti; Fiscal Year: 2013
    ..approximately four million individuals in the US and is the most common cause of dementia in North America and Europe. Genetic factors play an important role in the pathogenesis of AD...
  14. Evaluation of a new class of antimicrobial agents against Clostridium difficile
    SAUL R contact TZIPORI; Fiscal Year: 2011
    ..cause of diarrhea and intestinal inflammatory disease, has increased significantly in both North America and Europe, causing lengthy hospitalization and substantial morbidity and mortality...
  15. Predictors of Immunologic Failure in Older Adults
    David H Canaday; Fiscal Year: 2012
    ..S. and Europe. Frailty is a common condition in community dwelling elderly adults with a prevalence 7-10 % among those age 65, ..
  16. MLK3 in metabolic stress signaling
    Anja Jaeschke; Fiscal Year: 2013
    ..liver disease is the leading cause of liver dysfunction in non-alcoholic, viral hepatitis- negative populations in Europe and the USA...
  17. Biomimetic Approach to the Fabrication of Red Blood Cell Mimics
    Joseph M DeSimone; Fiscal Year: 2010
    ..and at this time there are no currently approved products for use as blood substitutes in North America or Europe. We propose in this application to take a biomimetic approach to the design of red blood cells (RBC) using a ..
  18. International Conf on Alzheimer Disease and Related Disorders in the Middle East
    Changiz Geula; Fiscal Year: 2013
    ..Alzheimer's disease is a major health problem and the leading cause of dementia in the Americas and Europe. There has been little work done on dementia in the Middle East...
  19. PROJECTED HEAT WAVE MAGNITUDES AND PUBLIC HEALTH IMPACTS
    Helene G Margolis; Fiscal Year: 2010
    ..g., more humid with higher nighttime temperatures). The 2003 EHE in Europe that led to >40,000 deaths, and the 2006 EHE in California that led to >600 deaths and >16,000 excess ..
  20. Determining Molecular Mechanisms of Chikungunya Virulence and Attenuation
    KATHERINE D RYMAN; Fiscal Year: 2010
    ..Furthermore, travelers returning to Europe, Canada and the United States from these areas have been diagnosed with the disease raising the possibility for ..
  21. HCV Strain Variation and HCC
    Andrea D Branch; Fiscal Year: 2012
    ..HCV is a major cause of HCC in the United States, Western Europe, and Japan and therefore it is critical to determine the molecular basis of the relationship between HCV and HCC...
  22. Outcomes and Predictors in Mild Cognitive Impairment
    Mary Ganguli; Fiscal Year: 2012
    ..Her group's epidemiological work , like those of other population-based studies in North America and Europe, has demonstrated that current "diagnostic" criteria for MCI do not reflect the real-world distribution and ..
  23. Histone modifications and respiratory effects of traffic particle exposure
    Lifang Hou; Fiscal Year: 2013
    ..5 levels typical of large cities in Europe/North America...
  24. Molecular probes for a vOTU from CCHFV using a fluorogenic peptide
    SCOTT DUSAN PEGAN; Fiscal Year: 2013
    ..Originally identified in Russia and the Congo, CCHF has rapidly spread across large sections of Europe, Asia, and Africa. Recently, U.S...
  25. E-Education in Research Ethics: Central and Eastern Europe
    MARTIN STROSBERG; Fiscal Year: 2013
    ..graduate level online/onsite advanced certificate program to build research ethics capacity in Central and Eastern Europe (CEE)...
  26. Protein inhibitor of galectin-3 to limit fibrosis after myocardial infarction
    MATTHEW LAWRENCE SPRINGER; Fiscal Year: 2013
    ..In humans, plasma levels of galectin-3 are approved by the US FDA and in Europe as a biomarker for risk of mortality in those with chronic heart failure (www.galectin-3...
  27. Children's Exposure to Flame Retardants: Effects on Thyroid Hormone Regulation
    Heather M Stapleton; Fiscal Year: 2012
    ..in the United States population relative to any other region measured, including other industrialized countries in Europe. Furthermore, children between the ages of 0-4 are predicted to have the highest exposure and body burdens of ..
  28. Epidemiology of testicular cancer in the Utah population
    Mia Hashibe; Fiscal Year: 2012
    ..It is one of the few cancers with increasing incidence over the last few decades in the US and Europe. In Utah, the age-adjusted incidence rates for men aged 15-49 years increased from 6.4 in 1973 to 13.8 in 2007...
  29. NIH Director's Pioneer Award
    Karl Deisseroth; Fiscal Year: 2009
    ..abstract_text> ..
  30. Epithelium, dendritic cells, and Clostridium difficile associated colitis
    Hanping Feng; Fiscal Year: 2013
    ..difficile infection (CDI) has increased significantly in both North America and Europe, causing lengthy hospitalization, substantial morbidity and mortality...
  31. Theiler?s virus as a potential cause of Vilyuisk encephalitis
    HOWARD LEE LIPTON; Fiscal Year: 2010
    ..In fact, the PI has just learned of SafV isolations from cases of encephalitis in children in Europe. Therefore, it is intriguing to speculate theiloviruses represent an emerging group of human viruses that cause ..
  32. SCABIES: BIOLOGY, CULTURE, HOST SPECIFICITY AND ANTIGENS
    Larry G Arlian; Fiscal Year: 2013
    ..In the United States and Europe, sporadic outbreaks occur in daycare centers, schools, work environments, the military, hostels, and among college ..
  33. 6th Orthomyxovirus Research Conference
    STACEY L SCHULTZ-CHERRY; Fiscal Year: 2012
    ..2005;Woods Hole, Massachusetts in 2007;and Freiberg, Germany in 2009 and were attended by young scientists from Europe, the U.S., Russia, Japan, and many other parts of the world...
  34. Preclinical development of a novel antibacterial for Clostridium difficile diseas
    George E Wright; Fiscal Year: 2012
    ..Incidence of CDAD is on the rise in the United States and Europe, and Cdiff is the major identified infectious cause of nosocomial diarrhea in patients to whom antibiotics had ..
  35. Developmental Genetic Epidemiology of Smoking
    Hermine H Maes; Fiscal Year: 2013
    ..more to liability to SI in later adolescence and young adulthood, 2) the rates of SI vary by culture (US, Europe, Australia), but variance components do not, 3) the influence of parents and parental smoking decreases and that ..
  36. MEMBRANE FUSION IN RETINAL ROD OUTER SEGMENTS
    KATHLEEN BOESZEBATTAGLIA; Fiscal Year: 2012
    ..are the most prevalent cause of autosomal dominant retinitis pigmentosa (adRP) in the United States and Northern Europe;over 150 mutations within this gene result in a broad variety of late onset progressive retinal dystrophies ..
  37. Risk prediction of atrial fibrillation: clinical, biological and genetic markers
    EMELIA J contact BENJAMIN; Fiscal Year: 2010
    ..In this grant, we propose to pool data from five prospective studies in the US and Europe to validate in a more diverse population, the previous Framingham score for AF, and to develop new risk scores ..
  38. Evaluation of the Effects of Chikungunya N-linked Glycosylation on Pathogenesis
    CHARLES EDWIN MCGEE; Fiscal Year: 2013
    ..and Southeast Asia [3-9] as well as the importation of human cases into the United States, the Caribbean, and Europe [8]. In some instances this has been followed by localized transmission cycles [10]...
  39. Hepatic expression of small hairpin RNA using gutless adenoviral vectors
    Nuria Morral; Fiscal Year: 2012
    ..In the USA, Europe and most westernized countries, type 2 diabetes affects ~6% of the population...
  40. Molecular Basis of Autosomal Dominant Hypercholesterolemia in a Multiethnic Cohor
    Zahid Ahmad; Fiscal Year: 2013
    ..Most of these studies were performed in ethnically and racially homogenous populations from Europe or Japan...
  41. Prevalance of Community-Acquired MRSA in Live Pigs and thier Human Handlers
    LYNDA UJU ODOFIN; Fiscal Year: 2010
    ..in spread of community-associated Methicillin Resistant Staphylococcus aureus (CA-MRSA);recent studies from Europe and Canada report a new strain (ST 398) that maybe associated with pig farming...
  42. Impact of Microparticles on Oral TSE Infections
    Joel A Pedersen; Fiscal Year: 2012
    ..Meat and bone meal (MBM), a commonly used cattle food supplement thought responsible for BSE in Europe. We present data demonstrating MBM is rich in microparticles and will test if MBM-associated agent enhances oral ..
  43. Identification of genes essential for survival of hypervirulent Kleb. pneumoniae
    Thomas A Russo; Fiscal Year: 2012
    ..reports were from the "Pacific Rim", but more recently hvKP has been described in the United States, Canada, Europe, Israel, Australia, South Africa and elsewhere...
  44. Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH)
    JILL PAMELA BUYON; Fiscal Year: 2013
    ..Two recent prospective studies (20 mothers from U.S. and 15 from Europe) utilizing an identical protocol of IVIG at replacement doses demonstrated 1) this intervention does not prevent ..
  45. EHEC-induced actin rearrangement and Stx2 translocation across epithelium
    John M Leong; Fiscal Year: 2012
    ..RELEVANCE: Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important food-borne pathogen in North America, Europe and Japan (79)...
  46. Immune Mechanisms in Choroidal Neovascularization
    Rajendra Apte; Fiscal Year: 2009
    ..AMD is the leading cause of blindness among the population over 65 years of age in North America, Europe and Australia. The morbidity from AMD is expected to rise exponentially as the population ages...
  47. Humoral responses to Lyme Borreliosis: A mouse model
    Nicole Baumgarth; Fiscal Year: 2012
    ..burgdorferi (Bb) and is the most commonly reported arthropod-borne illness in the US and Europe with the number of reported infections raising each year...
  48. DINUCLEOTIDE ISOMER AS A NOVEL ANTIVIRAL
    Radhakrishnan P Iyer; Fiscal Year: 2010
    ..About 180 million people are chronically infected with HCV worldwide with US (4.4 million) and Europe (12.8 million) representing approximately 10% of world's chronic HCV carriers...
  49. Radiation Force Imaging of Prostate Cancer and Guidance of Biopsy Procedures
    Kathryn Radabaugh Nightingale; Fiscal Year: 2013
    ..Screening methods are now widely used in the United States and Europe to detect PCa, which include digital rectal examination (DRE), and prostate-specific antigen (PSA) analysis...
  50. Development of a Manufacturing Process for a Novel TB Vaccine
    VIJAY YABANNAVAR; Fiscal Year: 2013
    ..company headquartered in Rockville, MD with laboratories and manufacturing facilities in the United States and Europe, collectively referred to as "Emergent" throughout this application...
  51. OspC regulation and pathogenic strategy of Borrelia burgdorferi
    Fang Ting Liang; Fiscal Year: 2013
    ..burgdorferi, which is transmitted by deer ticks, is the most common vector-borne illness in North America and Europe. Over 20,000 people contract the disease annually in the United States alone...
  52. Intraspecies Transmission and Infectivity of Insectivore-Borne Hantaviruses
    Richard Yanagihara; Fiscal Year: 2011
    ..One is a type of hemorrhagic fever with associated kidney failure occurring in Europe and Asia and the other is a rapidly progressive, frequently fatal respiratory disease occurring in the Americas...
  53. ADOLESCENT ANABOLIC STEROIDS, VASOPRESSIN AND AGGRESSION
    Richard H Melloni; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: From the U.S. to Europe and Australia anabolic steroid abuse remains high in the adolescent population...
  54. African Diversity and the Genetics of Human Health
    Joseph P Jarvis; Fiscal Year: 2011
    ..However, most studies of genetic architecture involve populations living in the United States, Europe and Asia...
  55. 11th International Symposium on the Maillard Reaction
    John W Baynes; Fiscal Year: 2012
    ..together ~300 scientists from academic and research institutions, government and industry, drawn equally from Europe, Australasia and the Americas...
  56. Vaccines for the Treatment of Opiate Addiction
    Kim D Janda; Fiscal Year: 2013
    ..Undeniably HIV prevalence related to intravenous drug use has risen dramatically in Eastern Europe, Asia, Iran, North Africa, and in Latin America...
  57. First Step: Home/School Intervention for Preschoolers with Disruptive Behaviors
    HILL M WALKER; Fiscal Year: 2013
    ..S., Canada, Australia, New Zealand and Europe converge in showing a path leading from early exposure to risk factors in family, neighborhood and community ..
  58. 2012 Proteoglycans Gordon Research Conference
    Robert J Linhardt; Fiscal Year: 2012
    ..The Proteoglycan conference is very international with over 33% of the attendees coming from Europe, Asia, Australia, South America and Africa...
  59. Integrative genomic analysis in hepatocellular carcinoma
    Josep M Llovet; Fiscal Year: 2011
    ..third cause of cancer-related death worldwide with the most rapidly rising cancer incidence in the US and Western Europe. The disease is a major public health problem, for which there are no molecular diagnostics and limited effective ..
  60. Regulation of BimEL phosphorylation in the pathogenesis of Huntington's disease
    Jianning Wei; Fiscal Year: 2012
    ..It has a prevalence of 3-10 affected subjects per 100,000 individuals in Western Europe and North America...
  61. Forms of Vitamin E Have Opposing Effects on Inflammation
    Joan M Cook-Mills; Fiscal Year: 2011
    ..in reducing inflammation in experimental asthma in mice and in asthmatics in studies in several countries in Europe (Finland and Italy). Disappointingly, vitamin E trials in the United States have failed to show benefit in asthma...
  62. A Luminal Vascular Coating to Prevent Intimal Hyperplasia Following Creation of a
    Kate Stuart; Fiscal Year: 2013
    ..However, between 23-46% of AVF in Europe and the US have problems with early failure or failure to mature, resulting in a primary patency of only 60-65% at ..
  63. Fifth International Conference on Alzheimer's Disease in the ME
    Changiz Geula; Fiscal Year: 2009
    ..Alzheimer's disease is a major health problem and the leading cause of dementia in the Americas and Europe. There has been little work done on dementia in the Middle East...
  64. NKT Cells Immunotherapy: Targeting Dendritic Cells with Glycolipid Liposomes
    Peng Wang; Fiscal Year: 2007
    ..response has been found in several clinical trials conducted by different teams in the United States, Japan and Europe. One of possible reasons might be that alpha-GalCer is too strong ligand that stuns the NKT cells to bring anergy...
  65. DRW HIV-Ab/HBsAg Duplex Rapid Test submission for FDA-PMA approval
    Helen Lee; Fiscal Year: 2009
    ..The test will be useful as a diagnostic test in the United States and Europe, and as a pre- and post-donation screening test in blood banks in developing countries especially those that ..
  66. A HTS Assay for Identifying Anti-Viral Drugs Against Arbovirus Infections
    Qianjun Li; Fiscal Year: 2007
    ..including Dengue virus (DNV) in Asia, West Nile virus (WNV) in North America and Bluetongue virus (BTV) in Europe. Arboviruses are unique because they are transmitted to their vertebrate hosts by arthropod vectors, therefore, ..
  67. A SARS-CoV Spike Protein Vaccine
    B Sim; Fiscal Year: 2005
    Severe acute respiratory syndrome (SARS) has been reported in Asia, North America, and Europe. In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of SARS...
  68. WORKSHOP ON THE ORAL MANIFESTATIONS OF HIV INFECTION
    John Greenspan; Fiscal Year: 2000
    ..Of these, about half will be from outside the U.S.A., notably from Africa, Asia, Europe, Canada, and Central/South America...
  69. Suboxone and Methadone for HIV Risk Reduction in Subutex Injectors
    GEORGE EDWARD WOODY; Fiscal Year: 2010
    ..addicted to opioids are injecting buprenorphine, mostly Subutex that is smuggled into the country from Western Europe. There are no data on how to treat these patients or how to best reduce their HIV risk, which is the focus of this ..
  70. Rural Environmental Health in Central/Eastern Europe
    Thomas Cook; Fiscal Year: 2002
    ..about agriculture and its relationship to rural health, occupational health and the environment in Central Europe, specifically to the Slovak and Czech Republics, Hungary, Poland, and the Ukraine; and (2) to facilitate ..
  71. Community-based Methamphetamine Use & HIV Risk in China
    Brian C Kelly; Fiscal Year: 2010
    ..by applicant): The use of methamphetamine has increased dramatically in recent years in the United States, Europe, Canada, Australia, and Asia...
  72. Novel Treatment for Degenerative Myopia
    JULIA KORNFIELD; Fiscal Year: 2009
    Myopia affects 30% of the population in the U.S. and Europe, and 70-90% of the population in some Asian countries. High myopia of greater than 8 diopters affects 0.2 0...
  73. US STUDY OF SEMEN QUALITY IN PARTNERS OF PREGNANT WOMEN
    Shanna Swan; Fiscal Year: 2001
    ..Protocols and questionnaires in use in Europe will be adapted minimally, as necessary for U.S. populations. Morphology and motility analyses of semen from all U...
  74. Cancer in the Middle Eastern Population in California
    Kiumarss Nasseri; Fiscal Year: 2004
    ..reason is that this population is currently classified as white in combination with other populations from Western Europe. Moreover, reliable methods for separating them do not exist...