singapore

Summary

Top Publications

  1. ncbi Prevalence of diabetes and ethnic differences in cardiovascular risk factors. The 1992 Singapore National Health Survey
    C E Tan
    Department of Endocrinology, Singapore General Hospital, Singapore
    Diabetes Care 22:241-7. 1999
  2. pmc Levels of cardiovascular disease risk factors in Singapore following a national intervention programme
    J Cutter
    Epidemiology and Disease Control Division, Ministry of Health, Singapore
    Bull World Health Organ 79:908-15. 2001
  3. pmc Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore
    Kwai Peng Chan
    Virology Laboratory, Department of Pathology, Singapore General Hospital, Outram Road, Singapore
    Emerg Infect Dis 9:78-85. 2003
  4. ncbi Epidemiology and control of hand, foot and mouth disease in Singapore, 2001-2007
    Li Wei Ang
    Communicable Diseases Division, Ministry of Health, Singapore
    Ann Acad Med Singapore 38:106-12. 2009
  5. ncbi 2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore
    Mark I C Chen
    Tan Tock Seng Hospital, Department of Clinical Epidemiology, 11 Jalan Tan Tock Seng, Singapore, 308433
    JAMA 303:1383-91. 2010
  6. pmc Transmission dynamics and control of severe acute respiratory syndrome
    Marc Lipsitch
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Science 300:1966-70. 2003
  7. pmc Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations
    Yik Ying Teo
    Centre for Molecular Epidemiology, National University of Singapore, Singapore 117597
    Genome Res 19:2154-62. 2009
  8. pmc Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey
    P J Foster
    Singapore National Eye Centre and Singapore Eye Research Institute, Singapore
    Br J Ophthalmol 87:1112-20. 2003
  9. ncbi Outdoor activity and myopia in Singapore teenage children
    M Dirani
    Singapore Eye Research Institute, and Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597
    Br J Ophthalmol 93:997-1000. 2009
  10. ncbi Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians
    Raghavan Lavanya
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Ophthalmic Epidemiol 16:325-36. 2009

Detail Information

Publications350 found, 100 shown here

  1. ncbi Prevalence of diabetes and ethnic differences in cardiovascular risk factors. The 1992 Singapore National Health Survey
    C E Tan
    Department of Endocrinology, Singapore General Hospital, Singapore
    Diabetes Care 22:241-7. 1999
    The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore.
  2. pmc Levels of cardiovascular disease risk factors in Singapore following a national intervention programme
    J Cutter
    Epidemiology and Disease Control Division, Ministry of Health, Singapore
    Bull World Health Organ 79:908-15. 2001
    To evaluate the impact of the National Healthy Lifestyle Programme, a noncommunicable disease intervention programme for major cardiovascular disease risk factors in Singapore, implemented in 1992.
  3. pmc Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore
    Kwai Peng Chan
    Virology Laboratory, Department of Pathology, Singapore General Hospital, Outram Road, Singapore
    Emerg Infect Dis 9:78-85. 2003
    b>Singapore experienced a large epidemic of hand, foot and mouth disease (HFMD) in 2000...
  4. ncbi Epidemiology and control of hand, foot and mouth disease in Singapore, 2001-2007
    Li Wei Ang
    Communicable Diseases Division, Ministry of Health, Singapore
    Ann Acad Med Singapore 38:106-12. 2009
    We reviewed the epidemiology of hand, foot and mouth disease (HFMD) in Singapore after the 2000 epidemic caused by Enterovirus 71 (EV71), with particular reference to the cyclical pattern, predominant circulating enteroviruses and impact ..
  5. ncbi 2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore
    Mark I C Chen
    Tan Tock Seng Hospital, Department of Clinical Epidemiology, 11 Jalan Tan Tock Seng, Singapore, 308433
    JAMA 303:1383-91. 2010
    b>Singapore experienced a single epidemic wave of 2009 influenza A(H1N1) with epidemic activity starting in late June 2009 and peaking in early August before subsiding within a month.
  6. pmc Transmission dynamics and control of severe acute respiratory syndrome
    Marc Lipsitch
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Science 300:1966-70. 2003
    ..With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of ..
  7. pmc Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations
    Yik Ying Teo
    Centre for Molecular Epidemiology, National University of Singapore, Singapore 117597
    Genome Res 19:2154-62. 2009
    The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1...
  8. pmc Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey
    P J Foster
    Singapore National Eye Centre and Singapore Eye Research Institute, Singapore
    Br J Ophthalmol 87:1112-20. 2003
    ..To describe risk factors for nuclear, cortical, and posterior subcapsular (PSC) cataracts in Chinese Singaporeans...
  9. ncbi Outdoor activity and myopia in Singapore teenage children
    M Dirani
    Singapore Eye Research Institute, and Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597
    Br J Ophthalmol 93:997-1000. 2009
    To investigate the relationship of outdoor activities and myopia in Singapore teenage children.
  10. ncbi Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians
    Raghavan Lavanya
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Ophthalmic Epidemiol 16:325-36. 2009
    ..This report summarizes the rationale and study design of the Singapore Indian Chinese Cohort (SICC) Eye Study, a population-based study of ethnic South Asian (Indians) and East Asian (..
  11. ncbi Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore
    H C Hapuarachchi
    National Environment Agency, Environmental Health Institute, Singapore
    J Gen Virol 91:1067-76. 2010
    ..the genetic Characteristics and evolutionary relationships of CHIKV strains that emerged in Sri Lanka and Singapore during 2006-2008...
  12. ncbi Rationale and methodology for a population-based study of eye diseases in Malay people: The Singapore Malay eye study (SiMES)
    Athena W P Foong
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Ophthalmic Epidemiol 14:25-35. 2007
    ..This study summarizes the rationale and study design of a population-based study of eye diseases among adult Malays in Singapore.
  13. pmc Genomic epidemiology of a dengue virus epidemic in urban Singapore
    Mark J Schreiber
    Novartis Institute for Tropical Diseases, Chromos, Singapore
    J Virol 83:4163-73. 2009
    ..and evolutionary profiles during the initial outbreak phase of a major dengue epidemic that took place in Singapore during 2005...
  14. pmc FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
    Jonathan T Tan
    Center for Molecular Epidemiology, National University of Singapore, Singapore, Singapore
    Diabetes 57:2851-7. 2008
    ..The aim of this study was to examine the effects of FTO variants on obesity and type 2 diabetes in Southeast Asian populations...
  15. pmc Influenza excess mortality from 1950-2000 in tropical Singapore
    Vernon J Lee
    Biodefence Center, Ministry of Defence, Singapore, Singapore
    PLoS ONE 4:e8096. 2009
    ..However, there is little information about the burden of annual tropical influenza epidemics across time, and the relationship between tropical influenza epidemics compared with other regions...
  16. ncbi Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study
    Tien Y Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 115:1869-75. 2008
    ..To describe the prevalence and risk factors of diabetic retinopathy in Asian Malays...
  17. pmc Dengue prevention and 35 years of vector control in Singapore
    Eng Eong Ooi
    Defense Medical and Environmental Research Institute, DSO National Laboratories, Singapore
    Emerg Infect Dis 12:887-93. 2006
    After a 15-year period of low incidence, dengue has reemerged in Singapore in the past decade. We identify potential causes of this resurgence...
  18. ncbi Identification of novel BRCA large genomic rearrangements in Singapore Asian breast and ovarian patients with cancer
    Y K Lim
    Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Clin Genet 71:331-42. 2007
    ..Using multiplex ligation-dependent probe amplification (MLPA), we have analyzed 100 Singapore patients who previously tested negative for deleterious BRCA mutations by the conventional polymerase chain ..
  19. ncbi Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Carcinogenesis 23:2055-61. 2002
    ..The Singapore Chinese Health Study is a prospective investigation among 63 257 middle-aged men and women, who were enrolled ..
  20. pmc Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms: the Singapore Chinese Health Study
    Tricia D LeVan
    Arizona Respiratory Center, University of Arizona, Tucson, AZ, USA
    Am J Epidemiol 163:1118-28. 2006
    ..evaluated the role of occupational exposures in asthma, chronic bronchitis, and respiratory symptoms in the Singapore Chinese Health Study, a population-based cohort of adults aged 45-74 years at enrollment in 1993-1998...
  21. ncbi Quantitative characterizations of speech rhythm: syllable-timing in Singapore English
    L E Ling
    National Institute of Education, Nanyang Technological University, English Language and Literature, 1 Nanyang Walk, Singapore 637616
    Lang Speech 43:377-401. 2000
    British English and Singapore English are said to differ in rhythmic patterning. British English is commonly described as stress-timed, but Singapore English is claimed to be syllable-timed...
  22. ncbi Use of traditional Chinese medicine in Singapore children: perceptions of parents and paediatricians
    C H Loh
    Medical School, Brookfield Health Sciences Complex, University College Cork, College Road, Cork, Ireland
    Singapore Med J 50:1162-8. 2009
    ..These are assessed in another arm of this study, with a set of predictive characteristics for their personal TCM use, their perceptions of herb/acupuncture safety, and their own referral to TCM eventually determined...
  23. ncbi Decision tree algorithm in deciding hospitalization for adult patients with dengue haemorrhagic fever in Singapore
    V J Lee
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Trop Med Int Health 14:1154-9. 2009
    ..To develop a simple decision tree for clinicians to decide between hospitalization and outpatient monitoring of adult dengue patients...
  24. pmc Economic analysis of pandemic influenza vaccination strategies in Singapore
    Vernon J Lee
    Center for Health Services Research, National University of Singapore, Singapore, Singapore
    PLoS ONE 4:e7108. 2009
    ..However, few studies have evaluated the cost-effectiveness of different vaccination strategies. This paper compares the economic outcomes of vaccination compared with treatment with antiviral agents alone, in Singapore.
  25. ncbi The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Lipid Res 44:2365-73. 2003
    b>Singapore comprises three ethnic groups: Chinese (76.7%), Malays (14%), and Asian-Indians (7.9%). Overall, Singaporeans experience coronary heart disease rates similar to those found in the United States...
  26. pmc Entomologic and virologic investigation of Chikungunya, Singapore
    Lee Ching Ng
    National Environment Agency, Singapore
    Emerg Infect Dis 15:1243-9. 2009
    Local transmission of chikungunya, a debilitating mosquito-borne viral disease, was first reported in Singapore in January 2008...
  27. ncbi DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study
    Mariana C Stern
    Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Room 5421A, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 16:2363-72. 2007
    Recently, we reported that among Singapore Chinese, cigarette smoking and alcohol drinking were independent risk factors for colorectal cancer...
  28. ncbi Predominance of subtype 3 among Blastocystis isolates from a major hospital in Singapore
    Kenneth H S Wong
    Laboratory of Molecular and Cellular Parasitology, National University of Singapore, Singapore 5 Science Drive 2, Singapore 117597, Singapore
    Parasitol Res 102:663-70. 2008
    ..In the present study, the prevalence of Blastocystis in 276 stool samples from a hospital in Singapore was examined, and for the first time, riboprinting using polymerase chain reaction-restriction fragment length ..
  29. pmc Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers
    Sunita Singh
    Programme in Infectious Diseases, Department of Microbiology, Faculty of Medicine, National University of Singapore, Singapore 117597
    J Clin Microbiol 40:2823-7. 2002
    A recent outbreak of hand, foot, and mouth disease in Singapore in 2000 affected several thousand children and resulted in four deaths...
  30. ncbi Hand, foot and mouth disease in Singapore: a comparison of fatal and non-fatal cases
    C Y Chong
    Department of Paediatric Medicine, KK Women s and Children s Hospital, Singapore, Republic of Singapore
    Acta Paediatr 92:1163-9. 2003
    An epidemic of hand, foot and mouth disease (HFMD) occurred in Singapore between September and November 2000. During the epidemic, there were four HFMD-related deaths and after the epidemic, another three HFMD-related deaths...
  31. pmc Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia
    P McMinn
    Department of Microbiology, Princess Margaret Hospital for Children, Subiaco, Western Australia 6008, Australia
    J Virol 75:7732-8. 2001
    ..viruses belonging to genogroups B3 and B4 have circulated endemically in Southeast Asia during this period and have been the primary cause of several large HFMD or encephalitis epidemics in Malaysia, Singapore, and Western Australia.
  32. pmc Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan
    Kuo Ming Yeh
    Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan
    J Clin Microbiol 45:466-71. 2007
    ..and the correlation of capsular serotype, magA, and rmpA with virulence, 73 isolates were collected in Singapore and Taiwan...
  33. pmc Reconstructing historical changes in the force of infection of dengue fever in Singapore: implications for surveillance and control
    Joseph R Egger
    Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England
    Bull World Health Organ 86:187-96. 2008
    To reconstruct the historical changes in force of dengue infection in Singapore, and to better understand the relationship between control of Aedes mosquitoes and incidence of classic dengue fever.
  34. pmc Use of mycobacterial interspersed repetitive unit-variable-number tandem repeat typing to examine genetic diversity of Mycobacterium tuberculosis in Singapore
    Yong Jiang Sun
    Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Republic of Singapore
    J Clin Microbiol 42:1986-93. 2004
    ..For this study, isolates from 291 patients in Singapore were genotyped by this method. One hundred sixty-six distinct MIRU-VNTR patterns were detected...
  35. ncbi Catastrophic extinctions follow deforestation in Singapore
    Barry W Brook
    Center for Ecological Research, Kyoto University, Otsu 520 2113, Japan
    Nature 424:420-6. 2003
    ..Here we report on local extinctions among a wide range of terrestrial and freshwater taxa from Singapore (540 km2) in relation to habitat loss exceeding 95% over 183 years...
  36. ncbi Population prevalence of tilted and torted optic discs among an adult Chinese population in Singapore: the Tanjong Pagar Study
    Alicia C S How
    Glaucoma Department, Singapore National Eye Centre and Singapore Eye Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Arch Ophthalmol 127:894-9. 2009
    To determine the prevalence of tilted and torted optic discs and associated risk factors among Chinese adults in Singapore.
  37. ncbi Detection of narrow angles and established angle closure in Chinese residents of Singapore: potential screening tests
    Winifred P Nolan
    Department of Ophthalmology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074
    Am J Ophthalmol 141:896-901. 2006
    ..To assess the performance of peripheral and central anterior chamber depth (ACD) measurements, and autorefraction, in identifying Chinese people with occludable drainage angles or established primary angle closure...
  38. ncbi The sequential introduction of HIV-1 subtype B and CRF01AE in Singapore by sexual transmission: accelerated V3 region evolution in a subpopulation of Asian CRF01 viruses
    Marcia L Kalish
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Virology 304:311-29. 2002
    ..To further characterize the dissemination of these strains regionally, we sequenced 58 strains from Singapore and found that subtype B and CRF01 were introduced separately, by homosexual and heterosexual transmission, ..
  39. ncbi Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore
    Jonathan T Tan
    Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Clin Endocrinol Metab 95:390-7. 2010
    ..However, the association in other East Asian populations is less well characterized...
  40. pmc Serological evidence for the co-circulation of multiple dengue virus serotypes in Singapore
    Annelies Wilder-Smith
    Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore
    Epidemiol Infect 133:667-71. 2005
    ..We did a seroepidemiological study to determine the circulating dengue virus serotypes and the extent to which the Singapore population has been exposed to multiple dengue virus serotypes, using the plaque reduction neutralization assay (..
  41. ncbi Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Carcinogenesis 26:976-80. 2005
    ..plasma estrogen and androstenedione levels in a cross-sectional study of healthy postmenopausal Chinese women in Singapore. In this group of 130 women, 84 were non or irregular (less than once a week) tea drinkers, 27 were regular (..
  42. ncbi An outbreak of primary dengue infection among migrant Chinese workers in Singapore characterized by prominent gastrointestinal symptoms and a high proportion of symptomatic cases
    Raymond C S Seet
    Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    J Clin Virol 33:336-40. 2005
    An outbreak of dengue occurred among Chinese migrant workers at a construction site in Singapore that was characterized by a number of unusual features.
  43. ncbi Green tea and black tea consumption in relation to colorectal cancer risk: the Singapore Chinese Health Study
    Can Lan Sun
    Division of Population Sciences, City of Hope National Medical Center and Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
    Carcinogenesis 28:2143-8. 2007
    The relationships between green tea and black tea consumption and colorectal cancer risk were examined within the Singapore Chinese Health Study, a prospective cohort study of diet and cancer involving >60,000 men and women...
  44. ncbi Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore
    B Zhao
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore 117597
    Cancer Epidemiol Biomarkers Prev 10:1063-7. 2001
    ..Conjugation and elimination of ITCs is enhanced in GST-non-null relative to -null individuals, such that the GST metabolic genotype modifies the protective effect of ITCs on lung cancer development...
  45. ncbi The prevalence and risk factors for pterygium in an adult Chinese population in Singapore: the Tanjong Pagar survey
    T Y Wong
    Singapore National Eye Centre and Eye Research Institute, 11 Third Hospital Ave, Singapore 168751, Singapore
    Am J Ophthalmol 131:176-83. 2001
    PURPOSE: To determine the prevalence and risk factors for pterygium in the Chinese population of Singapore. METHODS: A population-based survey was conducted in Singapore, an island located 1 degree north of the equator with a stable ..
  46. pmc A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women
    Lesley M Butler
    Department of Environmental, Colorado State University, Fort Collins, CO 80523 1681, USA
    Am J Clin Nutr 91:1013-9. 2010
    ..Prospective epidemiologic studies in Asian populations consistently show that soy is protective against breast cancer...
  47. ncbi Association between body mass index and chronic kidney disease in men and women: population-based study of Malay adults in Singapore
    Anoop Shankar
    Department of Community, Occupational, and Family Medicine, Singapore General Hospital, Singapore
    Nephrol Dial Transplant 23:1910-8. 2008
    ..In this context, we examined the relationship between BMI and CKD, by gender, in a study of Malay adults from Singapore.
  48. pmc AIDS-defining illnesses among patients with HIV in Singapore, 1985 to 2001: results from the Singapore HIV Observational Cohort Study (SHOCS)
    Richard Bellamy
    Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, Singapore
    BMC Infect Dis 4:47. 2004
    The objective was to describe the causes of initial and overall AIDS-defining disease episodes among HIV patients in Singapore.
  49. ncbi Contact screening and latent TB infection treatment in Singapore correctional facilities
    C B E Chee
    Department of Respiratory Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore
    Int J Tuberc Lung Dis 9:1248-52. 2005
    b>Singapore, a city-state with a tuberculosis (TB) incidence rate of 47 per 100000 population in 2000.
  50. ncbi Analysis of rpsL and rrs mutations in Beijing and non-Beijing streptomycin-resistant Mycobacterium tuberculosis isolates from Singapore
    Y J Sun
    Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore City, Republic of Singapore
    Clin Microbiol Infect 16:287-9. 2010
    ..1%) of alterations in streptomycin-resistant M. tuberculosis isolates from Singapore, with rpsL K43R being the most common rpsL mutation (82/92; 89%), which was significantly associated with ..
  51. ncbi The prevalence and descriptive epidemiology of atopic dermatitis in Singapore school children
    Y K Tay
    The National Skin Centre, 1 Mandalay Road, 308205, Singapore
    Br J Dermatol 146:101-6. 2002
    ..Atopic dermatitis is a common disease that appears to be increasing in frequency during recent decades. Most of the studies are based on the Western population, and there are few data in the Asian population...
  52. pmc High frequency of mutations in the rpoB gene in rifampin-resistant clinical isolates of Mycobacterium tuberculosis from Singapore
    Ann S G Lee
    J Clin Microbiol 43:2026-7. 2005
  53. ncbi Incidence of acute primary angle-closure glaucoma in Singapore. An island-wide survey
    S K Seah
    Singapore National Eye Centre, Republic of Singapore
    Arch Ophthalmol 115:1436-40. 1997
    To determine the incidence of acute primary angle-closure glaucoma (APACG) in Singapore and to identify demographic and meteorological risk factors.
  54. ncbi Component dependent risk factors for ocular parameters in Singapore Chinese children
    Seang Mei Saw
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, Republic of Singapore Singapore Eye Research Institute, Singapore, Republic of Singapore
    Ophthalmology 109:2065-71. 2002
    To examine the risk factors for variations in ocular biometry parameters in Singapore Chinese children, a population with a known high prevalence rate of myopia at an early age.
  55. ncbi Acute haemorrhagic conjunctivitis: seroepidemiology of coxsackievirus A24 variant and enterovirus 70 in Singapore
    K T Goh
    Quarantine and Epidemiology Department, Ministry of the Environment, Singapore
    J Med Virol 31:245-7. 1990
    ..caused by a variant of coxsackievirus A24 (CA24v) and enterovirus 70 (EV70) have occurred periodically in Singapore. A seroepidemiological survey conducted before the CA24v epidemic in 1985 and in the midst of the EV70 epidemic ..
  56. ncbi Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore
    Adrian Ong
    Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, 308433 Singapore
    Int J Infect Dis 11:263-7. 2007
    ..Associated with the rise of dengue has been the increase in dengue-associated mortality. To better understand the predictors of mortality, we conducted a review of hospitalized adult dengue infections within our institution...
  57. ncbi W135 meningococcal carriage in association with the Hajj pilgrimage 2001: the Singapore experience
    Annelies Wilder-Smith
    Department of Infectious Diseases, Travellers Health and Vaccination Centre, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    Int J Antimicrob Agents 21:112-5. 2003
    ..In Singapore, this strain is a new emerging problem, clearly associated with this outbreak...
  58. ncbi Visual impairment, causes of vision loss, and falls: the singapore malay eye study
    Ecosse L Lamoureux
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Vic, Australia
    Invest Ophthalmol Vis Sci 49:528-33. 2008
    ..To report associations of visual impairment and the main causes of vision loss with falls in an older Asian population...
  59. ncbi Outbreak of Nipah-virus infection among abattoir workers in Singapore
    N I Paton
    Department of Infectious Diseases, Communicable Disease Centre, Tan Tock Seng Hospital, Singapore
    Lancet 354:1253-6. 1999
    In March 1999, an outbreak of encephalitis and pneumonia occurred in workers at an abattoir in Singapore. We describe the clinical presentation and the results of investigations in these patients.
  60. ncbi Penetrating keratoplasty in Asian eyes: the Singapore Corneal Transplant Study
    Donald T H Tan
    Singapore National Eye Centre, Singapore
    Ophthalmology 115:975-982.e1. 2008
    The Singapore Corneal Transplant Study (SCTS) is a 16-year prospective study of 2100 consecutive corneal transplants performed between January 1991 and November 2006 in patients from Southeast Asia at a single tertiary center...
  61. pmc Sleep duration, melatonin and breast cancer among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Carcinogenesis 29:1244-8. 2008
    ..However, data are inconclusive from the three studies conducted in Western populations on sleep duration and breast cancer risk...
  62. pmc Gender-specific associations between soy and risk of hip fracture in the Singapore Chinese Health Study
    Woon Puay Koh
    Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Am J Epidemiol 170:901-9. 2009
    ..The authors examined gender-specific associations between soy intake and hip fracture risk in the Singapore Chinese Health Study, a prospective cohort of 63,257 Chinese living in Singapore...
  63. ncbi Relationships between indices of obesity and its co-morbidities in multi-ethnic Singapore
    M Deurenberg-Yap
    Research and Information Management, Health Promotion Board, Singapore
    Int J Obes Relat Metab Disord 25:1554-62. 2001
    ..by waist-to-hip ratio (WHR) on the cardiovascular risk factor profile of the three major ethnic groups in Singapore (Chinese, Malay and Indian people) and to determine if WHO recommended cut-off values for BMI and WHR are ..
  64. pmc Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study
    W P Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597, Singapore
    Br J Cancer 90:1760-4. 2004
    ..study of 310 colorectal cancer cases and 1177 controls in a nested prospective, population-based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase (COX)-2 -765G>C ..
  65. ncbi Viral agents responsible for febrile respiratory illnesses among military recruits training in tropical Singapore
    Shirley Gek Kheng Seah
    Detection and Diagnostics Laboratory, DSO National Laboratories, Singapore
    J Clin Virol 47:289-92. 2010
    ..Military personnel are highly susceptible to febrile respiratory illnesses (FRI), likely due to crowding, stress and other risk factors present in the military environment...
  66. pmc Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study
    W H Tsong
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Br J Cancer 96:821-7. 2007
    The relations were examined between colorectal cancer and cigarette smoking and alcohol consumption within the Singapore Chinese Health Study, a population-based, prospective cohort of 63 257 middle-aged and older Chinese men and women ..
  67. ncbi Seroepidemiology of dengue in the adult population of Singapore
    Annelies Wilder-Smith
    Department of Infectious Diseases, Tan Tock Seng Hospital, Jalan Tan Tock Seng, Singapore
    Trop Med Int Health 9:305-8. 2004
    ..We conducted a cross-sectional seroepidemiological study in Singapore to determine the extent at which the Singapore population has been exposed to dengue infections...
  68. ncbi Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and US
    Tanuja Rastogi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Int J Epidemiol 37:147-60. 2008
    ..Examining such rates may provide us with insights into future aetiological research possibilities as well as screening and prevention...
  69. ncbi Superficial fungal infections seen at the National Skin Centre, Singapore
    Hiok Hee Tan
    MIBBS, FRCP Bdin, FAMS
    Nihon Ishinkin Gakkai Zasshi 46:77-80. 2005
    Cutaneous fungal infections are common in Singapore. The National Skin Centre is a tertiary referral centre for dermatological diseases in the country, and sees more than 2,500 cases of superficial fungal infections annually.
  70. pmc Sleep duration and coronary heart disease mortality among Chinese adults in Singapore: a population-based cohort study
    Anoop Shankar
    Department of Community Medicine, West Virginia University School of Medicine, 1 Medical Center Drive, PO Box 9190, Morgantown, WV 26506 9190, USA
    Am J Epidemiol 168:1367-73. 2008
    ..the association between sleep duration and coronary heart disease (CHD) mortality among Chinese adults in Singapore (1993-2006), performing a prospective cohort study among 58,044 participants aged > or =45 years (55...
  71. ncbi International study on antidepressant prescription pattern at 20 teaching hospitals and major psychiatric institutions in East Asia: Analysis of 1898 cases from China, Japan, Korea, Singapore and Taiwan
    Naoki Uchida
    Fukuoka University College of Medicine, Fukuoka, Japan
    Psychiatry Clin Neurosci 61:522-8. 2007
    ..The survey was conducted in China, Japan, Korea, Singapore and Taiwan from October 2003 to March 2004 using the unified research protocol and questionnaire...
  72. ncbi Survival under chronic stress from sediment load: spatial patterns of hard coral communities in the southern islands of Singapore
    Angela Dikou
    Department of Environment, University of the Aegean, Xenia Building, University Hill, Mytilene 81100, Lesvos Islands, Greece
    Mar Pollut Bull 52:1340-54. 2006
    Six reef sites were chosen along the west coast of the southern islands of Singapore, at an increasing distance from the densely populated metropolitan area, to study the spatial patterns of coral reef communities on the upper reef slope ..
  73. ncbi Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore
    Jeanette Woon Pei Teo
    Department of Laboratory Medicine, National University Hospital, Singapore, Singapore
    Int J Antimicrob Agents 33:177-80. 2009
    ..Analysis of the genetic environment around the cloned qnrB genes showed that they were present in diverse plasmid backbones, sometimes within novel genetic contexts, but always associated with mobile or transposable elements...
  74. pmc Seroepidemiology of human enterovirus 71, Singapore
    Eng Eong Ooi
    Environmental Health Institute, National Environment Agency, Singapore
    Emerg Infect Dis 8:995-7. 2002
    ..The epidemiology of this viral infection is not well understood. We conducted a serologic survey in Singapore children, and the results indicate that infection occurs largely in preschool settings.
  75. ncbi Temporal trends and ethnic variations in amenable mortality in Singapore 1965-1994: the impact of health care in transition
    M Niti
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Int J Epidemiol 30:966-73. 2001
    ..This study was set up to examine the trends in amenable mortality in Singapore from 1965 to 1994; to estimate the relative impact of medical care and primary preventive policy measures in ..
  76. ncbi The singapore 5-Fluorouracil trabeculectomy study: effects on intraocular pressure control and disease progression at 3 years
    Tina T Wong
    Singapore National Eye Center, Singapore and Singapore Eye Research Institute, Singapore
    Ophthalmology 116:175-84. 2009
    ..To report 3-year results of a randomized, controlled trial comparing the use of a single application of 5-fluorouracil (5-FU) with placebo in trabeculectomy surgery...
  77. pmc Reproductive variables, soy intake, and lung cancer risk among nonsmoking women in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, 16 Medical Drive, MD3, National University of Singapore 117597, Singapore
    Cancer Epidemiol Biomarkers Prev 18:821-7. 2009
    ..soy isoflavonoid intake on lung cancer risk in a prospective cohort of middle-aged and elderly Chinese women in Singapore among whom 91% were lifetime nonsmokers. Among 35,298 women (mean follow-up time, 9...
  78. ncbi Cataract extraction rates among Chinese, Malays, and Indians in Singapore: a population-based analysis
    T Y Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
    Arch Ophthalmol 119:727-32. 2001
    ..To describe the rates of cataract extraction among Chinese, Malays, and Indians in an urban population in Asia...
  79. ncbi Presence of hemagglutination inhibition and neutralization antibodies to Japanese encephalitis virus in wild pigs on an offshore island in Singapore
    E ein See
    Defence Medical Research Institute, Defence Science and Technology Agency, 10 Medical Drive, Singapore 117597, Republic of Singapore
    Acta Trop 81:233-6. 2002
    ..and neutralization antibodies against Japanese encephalitis virus (JEV) in wild pigs on an offshore island in Singapore. Blood samples were collected from 28 wild pigs on the island...
  80. ncbi Epidemiology of skin disease among children in a referral skin clinic in Singapore
    C L Goh
    National Skin Centre, Singapore
    Pediatr Dermatol 11:125-8. 1994
    ..Epidemiologic data are useful in monitoring changes in disease trends in children and planning health care programs for them...
  81. pmc Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study
    Louis C Tan
    Department of Neurology, National Neuroscience Institute, Singapore
    Am J Epidemiol 167:553-60. 2008
    ..In 1993-2005, the authors examined these factors in relation to Parkinson's disease in the Singapore Chinese Health Study, a prospective cohort of 63,257 Chinese men and women...
  82. ncbi Pattern of third molar impaction in a Singapore Chinese population: a retrospective radiographic survey
    S L Quek
    Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, 5 Kent Ridge Road, Singapore 119054
    Int J Oral Maxillofac Surg 32:548-52. 2003
    ..It was concluded that the frequency of impacted third molars in the Singapore Chinese population studied was generally two to three times that reported in races of the Caucasian stock...
  83. ncbi Critical incidents in paediatric anaesthesia: an audit of 10 000 anaesthetics in Singapore
    C L Tay
    Department of Paediatric Anaesthesia, KK Women s and Children s Hospital, Singapore, Singapore
    Paediatr Anaesth 11:711-8. 2001
    ..perioperative incidents in the first 10000 anaesthetics administered in KK Women's and Children's Hospital in Singapore between May 1997 and April 1999...
  84. ncbi Willingness to donate blood samples for genetic research: a survey from a community in Singapore
    M L Wong
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Clin Genet 65:45-51. 2004
    ..3%); fear of discrimination (18.7%); and concerns about weakness (15.1%) and weight gain (9.4%). Public education programs to promote participation in genetic research should stress its benefits and address people's fears and concerns...
  85. ncbi Cytogenetic abnormalities in de novo acute myeloid leukemia in adults: relation to morphology, age, sex and ethnicity - a single center study from Singapore
    Anoop Kumar Enjeti
    Cytogenetics Laboratory, Department of Pathology, Singapore General Hospital, Singapore
    Hematol J 5:419-25. 2004
    ..The karyotypic patterns in AML patients from a single center in Singapore were studied and compared with reports from other regions of the world to identify possible geographic ..
  86. ncbi Regulatory control of Chinese Proprietary Medicines in Singapore
    Shen Kuan Yee
    Centre for Pharmaceutical Administration, Health Sciences Authority, Singapore, Singapore
    Health Policy 71:133-49. 2005
    In Singapore, there has been a growing public interest in traditional Chinese medicine (TCM), which plays an important role in the healthcare system...
  87. ncbi Characterization of pyrazinamide and ofloxacin resistance among drug resistant Mycobacterium tuberculosis isolates from Singapore
    Ann S G Lee
    Department of Clinical Research, Singapore General Hospital, Singapore
    Int J Infect Dis 6:48-51. 2002
    ..To evaluate rapid molecular approaches for the detection of pyrazinamide (PZA) and ofloxacin resistance, by screening 100 known drug-resistant Mycobacterium tuberculosis isolates...
  88. ncbi Attitudes as barriers in breast screening: a prospective study among Singapore women
    P T Straughan
    Department of Sociology, National University of Singapore, Singapore
    Soc Sci Med 51:1695-703. 2000
    ..In addition, findings reinforced the importance of social support from the family in the promotion of breast screening among Asian women...
  89. ncbi A comparative study of condom use and self-reported sexually transmitted infections between foreign Asian and local clients of sex workers in Singapore
    Mee Lian Wong
    Department of Community, Occupational and Family Medicine Faculty of Medicine, National University of Singapore
    Sex Transm Dis 32:439-45. 2005
    We conducted a survey to compare condom use and its associated factors between foreign Asian and local clients of female sex workers in Singapore.
  90. ncbi Dental caries prevalence and distribution among preschoolers in Singapore
    X L Gao
    Department of Preventive Dentistry Faculty of Dentistry, National University of Singapore
    Community Dent Health 26:12-7. 2009
    To describe the prevalence, severity and distribution of dental caries among preschoolers in Singapore.
  91. ncbi Improving adherence to regular pap smear screening among Asian women: a population-based study in Singapore
    Jeannette Lee
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore
    Health Educ Behav 29:207-18. 2002
    ..A community-based cross-sectional survey was carried out among 726 women (30-59 years) in Singapore. Although the overall screening prevalence was 62.4%, only 42% reported having regular smears...
  92. ncbi Sexually transmitted diseases and condom use among female freelance and brothel-based sex workers in Singapore
    M L Wong
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore
    Sex Transm Dis 26:593-600. 1999
    ..Most studies in Asia exclude freelance female sex workers because of difficulties in access and the illegality of their work. Data are lacking on their risk behaviors...
  93. pmc Genetic polymorphisms in KCNQ1, HERG, KCNE1 and KCNE2 genes in the Chinese, Malay and Indian populations of Singapore
    Seok Hwee Koo
    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Br J Clin Pharmacol 61:301-8. 2006
    To determine the genetic variability of long QT syndrome (LQTS)-associated genes (KCNQ1, HERG, KCNE1 and KCNE2) among three distinct ethnic groups in the Singapore population.
  94. ncbi Singapore Human Mutation/Polymorphism Database: a country-specific database for mutations and polymorphisms in inherited disorders and candidate gene association studies
    Ene Choo Tan
    Defense Medical and Environmental Research Institute, DSO National Laboratories, Republic of Singapore
    Hum Mutat 27:232-5. 2006
    ..Thus the Singapore Human Mutation/Polymorphism Database (SHMPD) was created to provide clinicians and scientists access to a ..
  95. ncbi Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population
    K T Moe
    Research and Development Unit, National Heart Centre, Singapore
    Eur J Neurol 15:1309-14. 2008
    ....
  96. ncbi Anaphylaxis in adults referred to a clinical immunology/allergy centre in Singapore
    B Y H Thong
    Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433
    Singapore Med J 46:529-34. 2005
    To study the clinical features and causes of anaphylaxis in consecutive adult patients referred to a clinical immunology/allergy centre in Singapore.
  97. ncbi Prevalence of cataract surgery and post-surgical visual outcomes in an urban Asian population: the Singapore Malay Eye Study
    R Lavanya
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, East Melbourne, VIC 3002 Australia
    Br J Ophthalmol 93:299-304. 2009
    ..The aim of the study was to describe the prevalence and visual outcomes of cataract surgery in an urban Asian population...
  98. ncbi The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-c30): validation of English version in Singapore
    N Luo
    Department of Pharmacy, National University of Singapore, Singapore
    Qual Life Res 14:1181-6. 2005
    ..This study aimed to validate the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30, English version 3.0) in Singaporean cancer patients...
  99. ncbi UGT1A1 haplotype mutation among Asians in Singapore
    Y Y Zhou
    Department of Paediatrics, Yong Loo Lin School of Medicine, National University, Singapore, Singapore
    Neonatology 96:150-5. 2009
    ..Some of the polymorphisms have been associated with an increased risk of neonatal hyperbilirubinemia which may explain the increased incidence of jaundice in an Asian population as well as exaggerated irinotecan-induced leukopenia...
  100. ncbi Questionnaire study on menstrual disorders in adolescent girls in Singapore
    Anupriya Agarwal
    J Pediatr Adolesc Gynecol 22:365-71. 2009
    ..The purpose of this study was to collect data on the characteristics of menstrual cycles in Singapore adolescents to determine the prevalence of menstrual abnormalities and the pattern of use of medical treatments ..
  101. ncbi Acanthamoeba keratitis associated with contact lens wear in Singapore
    Yong Ming Por
    Singapore National Eye Centre, Singapore, Republic of Singapore
    Am J Ophthalmol 148:7-12.e2. 2009
    ..To describe an outbreak of Acanthamoeba keratitis (AK) cases among contact lens wearers...

Research Grants62

  1. Prospective evaluation of IGF and IL-6 Dysregulation and Multiple Myeloma
    Graham A Colditz; Fiscal Year: 2010
    ..Professionals'Follow-up Study, the Women's Health Study, the Physician's Health Study, and the Singapore Chinese Cohort...
  2. Prospective studies of cancer etiology and prevention in Shanghai and Singapore
    Jian Min Yuan; Fiscal Year: 2013
    ..follow-up of the 81,501 middle-aged and older Chinese men and women participants of the Shanghai and Singapore cohort studies for another 5 five years, to accrue and validate a substantially increased number of cancer ..
  3. Exome re-sequencing candidate loci for familial essential tremor
    Barry E Kosofsky; Fiscal Year: 2012
    ..suggest a tight allelic association between ETM2 and the ET phenotype in populations from the United States, Singapore, and Korea...
  4. Functional analysis of mDia formins in hematopoietic stem cell engraftment and mi
    Peng Ji; Fiscal Year: 2010
    ..Tzutzuy Ramirez Hernandez and Maki Murata-Hori of the Temasek Life Sciences Laboratory in Singapore, the kinetic interactions of mDia1 and mDia2 with actin cytoskeletal proteins and how these interactions ..
  5. INTERNATIONAL GENETIC EPIDEMIOLOGY OF ORAL CLEFTS
    Terri H Beaty; Fiscal Year: 2013
    ..cleft lip, CL;cleft lip and palate, CLP;and cleft palate, CP) by recruiting cases from 5 sites (Maryland, Singapore, Taiwan, and 2 sites in China)...
  6. Biomarkers of NNK in prediction of lung cancer development in smokers
    Jian Min Yuan; Fiscal Year: 2013
    ..The Shanghai Cohort Study enrolled 18,244 men aged 45-64 years in Shanghai, China, during 1986-89. The Singapore Chinese Health Study enrolled 27,959 men and 35,298 women aged 45-74 years during 1993-98...
  7. An Integrated Study of Mitochondrial Pathways in Colorectal Cancer
    Bharat Thyagarajan; Fiscal Year: 2013
    ..study of 640 colorectal cancer cases and 1280 controls within a well-established prospective cohort, the Singapore Chinese Health Study...
  8. Analysis of mDia formins in hematopoietic stem cell engraftment and migration
    Peng Ji; Fiscal Year: 2013
    ..Tzutzuy Ramirez Hernandez and Maki Murata-Hori of the Temasek Life Sciences Laboratory in Singapore, the kinetic interactions of mDia1 and mDia2 with actin cytoskeletal proteins and how these interactions ..
  9. Demography of Sex Differences in Health and Survival
    James W Vaupel; Fiscal Year: 2013
    ..in Denmark (Project 2); Survey data on humans in the United States (Project 3) and in Japan, the Philippines and Singapore (Project 4); Longitudinal observations on baboons in the wild in Kenya (Project 5); Longitudinal data on lemurs ..
  10. Asia-ARVO Travel Awards and Symposium
    Sally S Atherton; Fiscal Year: 2010
    ..The 2011 Asia-ARVO meeting will be in Singapore (January 20-22, 2011)...
  11. Validating Biomarkers for the Prodrome and Transition to Psychosis in Shanghai
    Larry J Seidman; Fiscal Year: 2013
    ..Within the Asian Network for Early Psychosis, Taiwan and Singapore have started to address the putatively prodromal population...
  12. China Health and Retirement Longitudinal Study
    YAOHUI ZHAO; Fiscal Year: 2013
    ..2030, China's elderly population share is expected to reach 16%, greater than much richer countries such as Singapore, Malaysia, Israel, and Argentina...
  13. Genetic and Environmental Determinants of Type 2 Diabetes in Chinese Singaporeans
    Mark A Pereira; Fiscal Year: 2013
    ..Our main aim is the identification of genetic susceptibility factors for T2D in Chinese living in Singapore, where there is a high prevalence of T2D...
  14. THE SINGAPORE COHORT STUDY OF DIET AND CANCER
    Jian Min Yuan; Fiscal Year: 2009
    This is a request for continued funding of a residential cohort of 63,257 middle-aged and older (45-74 years) Singapore Chinese men and women accrued between 1993 and 1998...
  15. FASEB SRC on Regulation and Function of Small GTPases
    KAREN M CICHOWSKI; Fiscal Year: 2013
    ..There are 35 invited speakers from the United States, Europe, Singapore and Japan (all of which are confirmed)...
  16. Center for Computational Mass-Spectrometry
    Pavel A Pevzner; Fiscal Year: 2011
    ..US universities, hospitals and biotechnology companies, as well as foreign research institutions at Germany, Singapore, Spain, Sweden, and United Kingdom, we propose to further extend these collaborations by developing robust open ..
  17. Center for Computational Mass-Spectrometry
    Pavel A Pevzner; Fiscal Year: 2013
    ..US universities, hospitals and biotechnology companies, as well as foreign research institutions at Germany, Singapore, Spain, Sweden, and United Kingdom, we propose to further extend these collaborations by developing robust open ..
  18. Piezoelectric Pipetting for High Density Nucleic Acid Programmable Protein Arrays
    PETER J WIKTOR; Fiscal Year: 2013
    ..microarrays;world class production-scale automation process manufacturing equipment from an established Singapore based semiconductor production equipment manufacturer, Dr...
  19. Piezoelectric Pipetting for High Density Nucleic Acid Programmable Protein Arrays
    PETER J WIKTOR; Fiscal Year: 2011
    ..microarrays;world class production-scale automation process manufacturing equipment from an established Singapore based semiconductor production equipment manufacturer, Dr...
  20. Nutrition and Oral Clefts in Asia: Planning Grant
    Ronald G Munger; Fiscal Year: 2010
    ..case-control study of maternal nutritional and metabolic factors in oral clefts in the Philippines, Singapore, Taiwan, and China...
  21. Gene-environment-wide interaction studies of ocular refraction
    ROBERT J WOJCIECHOWSKI; Fiscal Year: 2013
    ..research will make use of 6 large datasets from genomic studies conducted in the United States, Germany, and Singapore. Our specific aims are to: 1) discover of genetic polymorphisms which interact with environmental factors in ..
  22. Developmental Origins and Epigenesis in Human Health and Disease
    Andrew D Robertson; Fiscal Year: 2010
    ..Judith Swain, Peter Gluckman, Michael Meaney and Anne Ferguson-Smith, which will be held in Singapore from April 26 - 30, 2010...
  23. Dissecting the Role of Src Family Kinases in Breast Cancer Brain Metastasis
    Siyuan Zhang; Fiscal Year: 2013
    ..D. degree in Cancer Biology from the National University of Singapore in 2005. My Ph.D...
  24. 5th International Conference on Epithelial Mesenchymal Transition
    RAYMOND BRUCE RUNYAN; Fiscal Year: 2011
    ..The meeting will be held Oct 10-13, 2011 in the Biopolis Center of Singapore under the auspices of the Epithelial-Mesenchymal Transition International Association (TEMTIA)...
  25. Pathogenic Roles of SHP2 &PTPRD Tyrosine Phosphatases in High-Risk Neuroblastoma
    Shizhen Zhu; Fiscal Year: 2013
    ..Building on Dr. Zhu's medical and scientific training in China and Singapore, she is now defining the roles of aberrant SHP2 and PTPRD tyrosine phosphatase pathways in the neuroblastoma ..
  26. Urinary metalloproteinases and ovarian cancer risk in a prospective cohort
    Lesley M Butler; Fiscal Year: 2013
    ..nested case- control study of 74 incident ovarian cancer cases and 222 individually matched controls within the Singapore Chinese Health Study, a population-based prospective cohort...
  27. Development of a Biomarker for Dietary Furanocoumarins
    SABRINA TRUDO; Fiscal Year: 2013
    ..and professional guidance in addition to the data and urine samples from a large prospective cohort in Singapore. First,we will modify existing methods for furanocoumarin analysis ofplants and various human biospecimens and ..
  28. Nipah Virus Pathobiology and Effects on Innate Immunity
    Linda Baum; Fiscal Year: 2009
    ..NiV infects agricultural livestock and humans;in 1999, NiV infection among agricultural workers in Malaysia and Singapore resulted in a 40% mortality rate and loss of livestock worth over $100 million...
  29. Urinary matrix metalloproteinases and breast cancer risk in a prospective cohort
    Lesley M Butler; Fiscal Year: 2013
    ..a nested case-control study of 470 incident breast cancer cases and 940 individually matched controls within the Singapore Chinese Health Study, a population-based prospective cohort...
  30. NATURAL HISTORY AND TREATMENT OUTCOME IN BRAIN AVM
    JP MOHR; Fiscal Year: 2005
    ..Following consensus, centers whose population-based capabilities (i.e., Singapore, a population of 4,000,000 served by three hospitals some of whose staff members trained with us) will provide a ..
  31. MR of Heart Iron: T2*/T2 Calibration & Application
    Dudley Pennell; Fiscal Year: 2006
    ..These centers are Philadelphia (USA), Cagliari (Italy), Athens (Greece), Nicosia (Cyprus), Mumbai (India) and Singapore.
  32. MOLECULAR BIOMARKERS
    GERALD WOGAN; Fiscal Year: 2001
    ..these will include Latinos, African Americans, Japanese and Whites; defined cohorts will also be studied in Singapore, China and Japan. In Project I, hemoglobin adducts will be used to determine the extent of human exposure to N...
  33. Comparative Study of Health Transitions in Later Life
    Zachary Zimmer; Fiscal Year: 2003
    ..of older populations in Taiwan (1989-1999), Indonesia (1993, 1997, 1998), the Philippines (1996, 2000-2001), and Singapore (1995, 1999)...
  34. Analysis of the Whole Genome CNV and SNP Data for Myopia from the SCORM Cohort
    Yi Ju Li; Fiscal Year: 2009
    ..In the present application, we propose to utilize whole genome association (WGA) SNP data from the Singapore Cohort study Of the Risk factors for Myopia (SCORM) study to advance our knowledge of CNV detection methods and ..
  35. INTERNATIONAL GENETIC EPIDEMIOLOGY OF ORAL CLEFTS
    Terri Beaty; Fiscal Year: 2001
    ..oral clefts based on case-parent trios (plus sib controls, where available) at 5 centers: Johns Hopkins (USA), Singapore, Taiwan, Hong Kong and Japan...
  36. Functional Materials Through Bottom-Up Self-Assembly - 2007 Supramolecules & Asse
    John Texter; Fiscal Year: 2007
    ..industrial and government scientists from the United States, the European Union, the former Soviet Union, China, Singapore, Australia and Japan...
  37. INTERNAT. CONSORTIUM FOR RESEARCH ON TMJ DISORDERS
    Samuel Dworkin; Fiscal Year: 2001
    ..directors at the Universities of Sydney, Australia; Helsinki, Finland; Halle-Leipsig, Germany; Tel Aviv, Israel; Singapore, Singapore; Oral Rehabilitation Center, Link'ping, Sweden; and in the United States, the consortium participants ..
  38. JHU-NUS Center for Research on CAMs(Planning Grant)
    PAUL LIETMAN; Fiscal Year: 2004
    ..The unique position of Johns Hopkins in Singapore and the attributes of Singapore itself make Singapore an excellent site for an NIH NCCAM regional International ..
  39. INTERNATIONAL CENTERS AGAINST ORAL CANCER
    STIMSON SCHANTZ; Fiscal Year: 2001
    ..in Sao Paulo, Brazil, the Free University Hospital in Amsterdam, the Netherlands, the National Cancer Center of Singapore, and the Tata Memorial Center in Bombay. These combined centers evaluate over 3000 oral cancer patients annually...
  40. ADV MINORITIES' GLOBAL RES TRAINING IN NEW MILLENIUM
    KIM TAN; Fiscal Year: 2003
    ..The foreign research laboratories selected are the University of Helsinki and the National University of Singapore. The decision to continue with these two universities is based on their long-term commitment and success track ..
  41. ANDROGEN RECEPTOR AND PROSTATE CANCER RISK IN CHINESE
    Gerhard Coetzee; Fiscal Year: 2003
    ..AR genotypes and prostate cancer risk, by assembling cases and controls among genetically homogeneous Chinese of Singapore, and by screening for somatic mutations in the AR gene...
  42. COHORT STUDY OF DIET AND NASOPHYARYNGEAL CANCER
    MIMI YU; Fiscal Year: 1992
    The primary goal of the proposed cohort study in Singapore is to definitively establish Chinese salted fish as a human carcinogen...
  43. JOHNS HOPKINS CENTER FOR CANCER COMPLEMENTARY MEDICINE
    Adrian Dobs; Fiscal Year: 2004
    ..Our mission is strengthened by international links with our Johns Hopkins Singapore campus and access serve as teachers and mentors...
  44. Retinal Microvascular Signs and CVD in Older Persons
    Tien Wong; Fiscal Year: 2005
    ..This may ultimately lead to improved identification, and preventive and therapeutic strategies for the most common causes of morbidity, disability and mortality affecting elderly people in the United States. ..
  45. PREVALENCE AND IMPACT OF GLAUCOMA AMONG THE VERY ELDERLY
    David Friedman; Fiscal Year: 2003
    ..Finally, the interactions between comorbidities (including cognitive deficits) and visual field loss will be explored. ..
  46. Domoic Acid and Neonatal Microglia Activation
    Alejandro Mayer; Fiscal Year: 2004
    ..activated microglia cells and their mediators play in DOM-induced excitotoxic neuronal injury and thus contribute to potential novel approaches for the therapy of the neuropathology associated with Amnesic Shellfish Poisoning in humans ..
  47. Cancer Incidence among Transplant Recipients:1990-2001
    LESLEY BUTLER; Fiscal Year: 2004
    ..abstract_text> ..
  48. DIETARY AND GENETIC DETERMINANTS OF MAMMOGRAPHIC DENSITY
    Anna Wu; Fiscal Year: 2008
    ..We propose to conduct a cost-effective cross-sectional study among 2,200 postmenopausal Chinese women in Singapore who were participants of both the Singapore Chinese Health Study, a prospective cohort study of cancer, and the ..
  49. METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINES
    Stephen Hecht; Fiscal Year: 2003
    ..abstract_text> ..
  50. Tobacco Carcinogenesis
    Stephen Hecht; Fiscal Year: 2005
    ..Steven Tannenbaum (MIT), Dr. Jack Henningfield (Johns Hopkins and Pinney Associates), Drs. Jeffrey Seeman and Anthony Tricker (Philip Morris), and Dr. John Lauterbach (an independent consultant, formerly with Brown and Williamson). ..
  51. Lung Cancer Chemoprevention: Isothiocyanates, inositol
    Stephen Hecht; Fiscal Year: 2008
    ..abstract_text> ..
  52. Comparative Study of Health Transitions in Later Life
    MARY OFSTEDAL; Fiscal Year: 2003
    ..of older populations in Taiwan (1989-1999), Indonesia (1993, 1997, 1998), the Philippines (1996, 2000-2001), and Singapore (1995, 1999)...
  53. LIPID PEROXIDATION IN COLORECTAL CANCER
    Manuela Gago Dominguez; Fiscal Year: 2009
    ..4. To conduct a case-case association study to determine if morphological markers of apoptosis in tumor and surrounding free tissue differ among cases with varying exposure levels of a given putative environmental/genetic risk factor. ..
  54. CARCINOGENIC CYCLIC NITROSAMINE DNA ADDUCTS
    Stephen S Hecht; Fiscal Year: 2010
    ..The proposed research is significant because of the known human exposure to these carcinogens through the diet, tobacco products, and endogenous formation. ..
  55. Epidemiologic Methods: Resistant Nosocomial Infections
    Marc Lipsitch; Fiscal Year: 2004
    ..This will in turn lead to better practices to reduce the incidence of ARNI. ..
  56. Genetic Variability and Virulence of Human Adenovirus 7
    Adriana Kajon; Fiscal Year: 2005
    ..abstract_text> ..
  57. Mammographic density, genes and estradiol/norethisterone based EPT regimens
    Giske Ursin; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  58. Primate enteroviruses transmission in Bangladesh
    Lisa Jones Engel; Fiscal Year: 2007
    ..Ultimately, this data will provide insight into the potential emergence of NHP-borne pathogens and help to deter the spread of emerging zoonotic threats. [unreadable] [unreadable]..
  59. PAT PROTEINS: GENE-DIET INTERACTIONS OBESITY RISK AND HEALTH
    Jose Ordovas; Fiscal Year: 2009
    ....
  60. Breast Cancer Survival: Lifestyle and Genetic Determinants
    Xiao Ou Shu; Fiscal Year: 2010
    ..The proposed study, built on successfully implemented cohort studies, will be extremely timely and cost-efficient. ..
  61. Soyfood, gene polymorphisms and endometrial cancer risk
    Xiao Ou Shu; Fiscal Year: 2010
    ..abstract_text> ..
  62. EXERCISE TRAINING IN OLDER HYPERTENSIVE MEN AND WOMEN
    Kerry Stewart; Fiscal Year: 2002
    ..The results from this study will expand the scientific knowledge that defines exercise guidelines for older men and women at risk for CVD because of their BP levels. ..