japan

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Top Publications

  1. ncbi Revised equations for estimated GFR from serum creatinine in Japan
    Seiichi Matsuo
    Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Kidney Dis 53:982-92. 2009
  2. ncbi Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooperative Study in Japan
    Y Ohe
    Department of Internal Medicine, National Cancer Center Hospital, Tokyo, Japan
    Ann Oncol 18:317-23. 2007
  3. ncbi Diabetes mellitus and the risk of cancer: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Arch Intern Med 166:1871-7. 2006
  4. ncbi Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years: the INTERMAP study
    Cheryl A M Anderson
    Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    J Am Diet Assoc 110:736-45. 2010
  5. ncbi COPD in Japan: the Nippon COPD Epidemiology study
    Yoshinosuke Fukuchi
    Department of Respiratory Medicine, Juntendo University, Tokyo, Japan
    Respirology 9:458-65. 2004
  6. ncbi Outbreak of central nervous system disease associated with hand, foot, and mouth disease in Japan during the summer of 2000: detection and molecular epidemiology of enterovirus 71
    Tsuguto Fujimoto
    Infectious Disease Research Division, Hyogo Prefectural Institute of Public Health and Environmental Sciences, Kobe, Japan
    Microbiol Immunol 46:621-7. 2002
  7. pmc A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan
    Seigo Kitano
    Department of Surgery I, Oita University Faculty of Medicine, Yufu, Oita, Japan
    Ann Surg 245:68-72. 2007
  8. ncbi Biliary tract cancer treatment: 5,584 results from the Biliary Tract Cancer Statistics Registry from 1998 to 2004 in Japan
    Shuichi Miyakawa
    Department of Biliary and Pancreatic Surgery, Fujita Health University, Toyoake, Aichi, Japan
    J Hepatobiliary Pancreat Surg 16:1-7. 2009
  9. ncbi Genetic changes of coxsackievirus A16 and enterovirus 71 isolated from hand, foot, and mouth disease patients in Toyama, Japan between 1981 and 2007
    Masae Iwai
    Department of Virology, Toyama Institute of Health, Imizu shi, Toyama, Japan
    Jpn J Infect Dis 62:254-9. 2009
  10. ncbi Prevalence and clinicoepidemiological features of moyamoya disease in Japan: findings from a nationwide epidemiological survey
    Shinichi Kuriyama
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
    Stroke 39:42-7. 2008

Detail Information

Publications309 found, 100 shown here

  1. ncbi Revised equations for estimated GFR from serum creatinine in Japan
    Seiichi Matsuo
    Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Kidney Dis 53:982-92. 2009
    ..Our previously reported GFR-estimating equations for Japanese had limitations because all participants had a GFR less than 90 mL/min/1.73 m2 and serum creatinine was assayed in different laboratories...
  2. ncbi Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooperative Study in Japan
    Y Ohe
    Department of Internal Medicine, National Cancer Center Hospital, Tokyo, Japan
    Ann Oncol 18:317-23. 2007
    ..To compare the efficacy and toxicity of three platinum-based combination regimens against cisplatin plus irinotecan (IP) in patients with untreated advanced non-small-cell lung cancer (NSCLC) by a non-inferiority design...
  3. ncbi Diabetes mellitus and the risk of cancer: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Arch Intern Med 166:1871-7. 2006
    ..An association between diabetes mellitus (DM) and cancer has long been speculated, but no conclusive evidence has been obtained...
  4. ncbi Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years: the INTERMAP study
    Cheryl A M Anderson
    Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    J Am Diet Assoc 110:736-45. 2010
    ..INTERMAP is an international, cross-sectional, epidemiologic study of 4, 680 individuals ages 40 to 59 years from Japan (four samples), People's Republic of China (three rural samples), the United Kingdom (two samples), and the United ..
  5. ncbi COPD in Japan: the Nippon COPD Epidemiology study
    Yoshinosuke Fukuchi
    Department of Respiratory Medicine, Juntendo University, Tokyo, Japan
    Respirology 9:458-65. 2004
    ..Despite high smoking rates, few prevalence studies of COPD have been performed in Asia. The Nippon COPD Epidemiology (NICE) Study used spirometry to measure prevalence of airflow limitation in Japanese adults...
  6. ncbi Outbreak of central nervous system disease associated with hand, foot, and mouth disease in Japan during the summer of 2000: detection and molecular epidemiology of enterovirus 71
    Tsuguto Fujimoto
    Infectious Disease Research Division, Hyogo Prefectural Institute of Public Health and Environmental Sciences, Kobe, Japan
    Microbiol Immunol 46:621-7. 2002
    ..the serious enterovirus 71 (EV71) infections, which affect the central nervous system (CNS), had been reported in Japan before 2000...
  7. pmc A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan
    Seigo Kitano
    Department of Surgery I, Oita University Faculty of Medicine, Yufu, Oita, Japan
    Ann Surg 245:68-72. 2007
    ..We conducted a retrospective, multicenter study of a large series of patients in Japan to evaluate the short- and long-term outcomes of laparoscopic gastrectomy for early gastric cancer (EGC).
  8. ncbi Biliary tract cancer treatment: 5,584 results from the Biliary Tract Cancer Statistics Registry from 1998 to 2004 in Japan
    Shuichi Miyakawa
    Department of Biliary and Pancreatic Surgery, Fujita Health University, Toyoake, Aichi, Japan
    J Hepatobiliary Pancreat Surg 16:1-7. 2009
    ..In the present study, we report here selectively summarized data as an overview of the 2006 follow-up survey of the registered cases from 1998 to 2004 for information bearing on problems with the treatment of cancer of the biliary tract...
  9. ncbi Genetic changes of coxsackievirus A16 and enterovirus 71 isolated from hand, foot, and mouth disease patients in Toyama, Japan between 1981 and 2007
    Masae Iwai
    Department of Virology, Toyama Institute of Health, Imizu shi, Toyama, Japan
    Jpn J Infect Dis 62:254-9. 2009
    ....
  10. ncbi Prevalence and clinicoepidemiological features of moyamoya disease in Japan: findings from a nationwide epidemiological survey
    Shinichi Kuriyama
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
    Stroke 39:42-7. 2008
    The objectives of the present study were to estimate an annual number of patients with moyamoya disease in Japan and to describe the clinicoepidemiological features of the disease.
  11. ncbi The resurgence of Shamonda virus, an African Simbu group virus of the genus Orthobunyavirus, in Japan
    T Yanase
    Kyushu Research Station, National Institute of Animal Health, 2702 Chuzan, Kagoshima 891 0105, Japan
    Arch Virol 150:361-9. 2005
    ..biting midges and blood samples of sentinel cattle in Kagoshima and Miyazaki Prefectures, the southern part of Japan, in 2002...
  12. pmc Coexistence of multiple genotypes, including newly identified genotypes, in outbreaks of gastroenteritis due to Norovirus in Japan
    Tsutomu Kageyama
    Department of Clinical Genomics, BML, Inc, Matoba 1361 1, Kawagoe, Saitama 350 1101, Japan
    J Clin Microbiol 42:2988-95. 2004
    ..study, we investigated the molecular epidemiology of NV from 66 outbreaks that occurred in Saitama Prefecture, Japan, from 1997 to 2002...
  13. ncbi Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition
    Masahiro Asaka
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Helicobacter 15:1-20. 2010
    Over the past few years, the profile of Helicobacter pylori infection has changed in Japan. In particular, the relationship between H. pylori and gastric cancer has been demonstrated more clearly...
  14. ncbi Enterovirus 71 from fatal and nonfatal cases of hand, foot and mouth disease epidemics in Malaysia, Japan and Taiwan in 1997-1998
    H Shimizu
    Department of Virology II, National Institute of Infectious Diseases, Tokyo 208 0011, Japan
    Jpn J Infect Dis 52:12-5. 1999
    ..In 1997, in Malaysia and Japan, and in 1998 in Taiwan, there were HFMD epidemics involving sudden deaths among young children, and EV71 was ..
  15. ncbi Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy
    H Yoshida
    Department of Gastroenterology, University of Tokyo, Japan
    Ann Intern Med 131:174-81. 1999
    ..Previous studies on the effect of interferon therapy on the incidence of hepatocellular carcinoma have not sufficiently assessed degree of liver fibrosis, a major risk factor for hepatocellular carcinoma...
  16. ncbi Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    David A Goodkin
    Amgen Inc, Thousand Oaks, California, USA
    J Am Soc Nephrol 14:3270-7. 2003
    ..a prospective, observational study of representative samples of hemodialysis patients in France, Germany, Italy, Japan, Spain, the United Kingdom, and the United States (US) that captures extensive data relating to patient ..
  17. ncbi Prevalence of Epstein-Barr virus in Japan: trends and future prediction
    Kengo Takeuchi
    Department of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Koto, Japan
    Pathol Int 56:112-6. 2006
    ..This result suggests that the delay will affect the incidence of EBV-associated disorders in Japan.
  18. ncbi A randomized study of screening for ovarian cancer: a multicenter study in Japan
    H Kobayashi
    Department of Obstetrics and Gynecology, Nara Medical University, Nara, Japan
    Int J Gynecol Cancer 18:414-20. 2008
    ..2 years, in Shizuoka district, Japan. The original intention was to offer women in the intervention group annual screens by gynecological examination (..
  19. ncbi Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 160:381-407. 2003
    ..Lifetime risk summaries are used to examine uncertainties of the LSS noncancer disease findings...
  20. ncbi Isolation and genotyping of potentially pathogenic Acanthamoeba and Naegleria species from tap-water sources in Osaka, Japan
    Akiko Edagawa
    Division of Environmental Health, Osaka Prefectural Institute of Public Health, Osaka, Japan
    Parasitol Res 105:1109-17. 2009
    ..free-living amoebae (FLA) in tap-water sources from rivers and water treatment plants located in Osaka Prefecture, Japan. A total of 374 raw water samples were collected from 113 sampling points...
  21. pmc The shift of residents from university to non-university hospitals in Japan: a survey study
    Kyoko Nomura
    Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan
    J Gen Intern Med 23:1105-9. 2008
    Between 2003 and 2004, when the new postgraduate medical education program was introduced in Japan, the number of university residents decreased from 5,923 to 3,264 (-31%), whereas the number of non-university residents increased from 2,..
  22. ncbi Chronic Kidney Disease Japan Cohort (CKD-JAC) study: design and methods
    Enyu Imai
    Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Japan
    Hypertens Res 31:1101-7. 2008
    The prevalence and incidence of end-stage renal disease (ESRD) in Japan are the highest and the third highest, respectively, in the world, while the incidence of cardiac death in Japan is the lowest among developed countries...
  23. ncbi Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes
    Michael F Hammer
    Division of Biotechnology, University of Arizona, Tucson, AZ 85721, USA
    J Hum Genet 51:47-58. 2006
    ..of Y chromosome short tandem repeat diversity indicated that haplogroups D and C began their expansions in Japan approximately 20,000 and approximately 12,000 years ago, respectively, while haplogroup O-47z began its expansion ..
  24. ncbi Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score)
    Masatoshi Kudo
    Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama 589 8511, Japan
    J Gastroenterol 38:207-15. 2003
    ..In contrast, a new staging system based on the Liver Cancer Study Group of Japan (LCSGJ), the Japan Integrated Staging (JIS) score is currently proposed in Japan...
  25. ncbi Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial
    Haruo Nakamura
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Lancet 368:1155-63. 2006
    Evidence-based treatment for hypercholesterolaemia in Japan has been hindered by the lack of direct evidence in this population...
  26. ncbi Baseline survey of JPHC study--design and participation rate. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    J Epidemiol 11:S24-9. 2001
    ..These data and blood samples serve as basis for the Japan Public Health Center-based prospective Study on cancer and cardiovascular diseases (JPHC Study).
  27. ncbi The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 8:317-23. 2007
    The Japan Multi-institutional Collaborative Cohort Study (J-MICC Study) launched in 2005, supported by a research grant for Scientific Research on Special Priority Areas of Cancer from the Japanese Ministry of Education, Culture, Sports, ..
  28. ncbi Prognosis and risk factors for idiopathic membranous nephropathy with nephrotic syndrome in Japan
    Hideo Shiiki
    First Department of Internal Medicine, Nara Medical University, Nara, Japan
    Kidney Int 65:1400-7. 2004
    Idiopathic membranous nephropathy (IMN) is a representative form of refractory nephrotic syndrome in Japan. Although IMN is thought to run a more benign course in Japanese than in the Caucasian population, risk factors and appropriate ..
  29. ncbi Genetic diversity of enterovirus 71 associated with hand, foot and mouth disease epidemics in Japan from 1983 to 2003
    Mitsuaki Hosoya
    Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan
    Pediatr Infect Dis J 25:691-4. 2006
    ..The surveillance data indicate that EV71 infection follows an epidemic mode of transmission, causing large outbreaks and then becoming quiescent for a few years...
  30. ncbi Health problems due to long working hours in Japan: working hours, workers' compensation (Karoshi), and preventive measures
    Kenji Iwasaki
    Institute of Industrial Health, National Institute of Occupational Safety and Health, Nagao, Kawasaki, Japan
    Ind Health 44:537-40. 2006
    Late in the 1970s, serious social concern over health problems due to long working hours has arisen in Japan. This report briefly summarizes the Japanese circumstances about long working hours and what the Government has achieved so far...
  31. ncbi Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese
    Tamio Teramoto
    Committee for Epidemiology and Clinical Management of Atherosclerosis, Japan
    J Atheroscler Thromb 14:45-50. 2007
  32. ncbi Changing site distribution of colorectal cancer in Japan
    Hideho Takada
    Department of Surgery, Kouri Hospital, Kansai Medical University, Osaka, Japan
    Dis Colon Rectum 45:1249-54. 2002
    ..We wanted to determine whether any similar change has occurred in Japan, and where the incidence of this disease has increased sharply.
  33. ncbi Control of blood pressure as measured at home and office, and comparison with physicians' assessment of control among treated hypertensive patients in Japan: First Report of the Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) study
    Takayoshi Ohkubo
    Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
    Hypertens Res 27:755-63. 2004
    The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) study was conducted to measure the control of blood pressure (BP) as evaluated by home BP measurement among 3,400 patients with essential hypertension (mean age: ..
  34. ncbi The organization and financing of end-stage renal disease treatment in Japan
    Shunichi Fukuhara
    Department of Epidemiology and Healthcare Research, Kyoto University Graduate School of Medicine and Public Health, Kyoto, Japan
    Int J Health Care Finance Econ 7:217-31. 2007
    ..Renal transplantation is rare in Japan. In private dialysis clinics, the majority of treatment costs are paid as fixed fees per session and the rest are ..
  35. ncbi IFCC reference system for measurement of hemoglobin A1c in human blood and the national standardization schemes in the United States, Japan, and Sweden: a method-comparison study
    Wieland Hoelzel
    Roche Diagnostics GmbH, Penzberg, Germany
    Clin Chem 50:166-74. 2004
    ..of hemoglobin (Hb)A(1c) measurements in the US [National Glycohemoglobin Standardization Program (NGSP)], Japan [Japanese Diabetes Society (JDS)/Japanese Society of Clinical Chemistry (JSCC)], and Sweden are based on different ..
  36. ncbi Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study
    Shinichi Kuriyama
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    JAMA 296:1255-65. 2006
    ..Green tea polyphenols have been extensively studied as cardiovascular disease and cancer chemopreventive agents in vitro and in animal studies. However, the effects of green tea consumption in humans remain unclear...
  37. ncbi Prevalence of functional dyspepsia in an outpatient clinic with primary care physicians in Japan
    Toshikatsu Okumura
    Department of General Medicine, Asahikawa Medical College, 2 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
    J Gastroenterol 45:187-94. 2010
    ..patients with functional gastrointestinal disorders (FGID), this study was performed to clarify the prevalence of FGID, especially functional dyspepsia (FD), in new patients of an outpatient clinic with primary care physicians in Japan.
  38. pmc Emerging genotypes of human respiratory syncytial virus subgroup A among patients in Japan
    Yugo Shobugawa
    Department of Infectious Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Niigata City, Japan
    J Clin Microbiol 47:2475-82. 2009
    ..We report the molecular epidemiology of HRSV in Niigata, Japan, over six successive seasons (from 2001 to 2007) and the emerging genotypes of HRSV subgroup A (HRSV-A) strains...
  39. pmc Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan
    Yoshikazu Inoue
    Bioscience Medical Research Center, Niigata University Medical and Dental Hospital, 754 Ichibannchoh, Asahimachi Tohri, Niigata 951 8520, Japan
    Am J Respir Crit Care Med 177:752-62. 2008
    ..Because PAP is rare, prior reports were based on limited patient numbers or a synthesis of historical data...
  40. ncbi Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) Study
    Kazumasa Yamagishi
    Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, and Institute of Community Medicine, University of Tsukuba, Tsukuba, Japan
    J Am Coll Cardiol 52:988-96. 2008
    ....
  41. ncbi The BioBank Japan Project
    Yusuke Nakamura
    Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Clin Adv Hematol Oncol 5:696-7. 2007
  42. ncbi Discovery of novel [Arg49]phospholipase A2 isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A2 isozymes in the southwestern islands of Japan and Taiwan
    Takahito Chijiwa
    Department of Applied Life Science, Faculty of Bioscience, Sojo University, 4 22 1 Ikeda, Kumamoto 860 0082, Japan
    Toxicon 48:672-82. 2006
    ..Trimeresurus) elegans, a Crotalinae snake, inhabits Ishigaki and Iriomote islands of the Sakishima Islands of Japan which are located between Okinawa island of Japan and Taiwan...
  43. ncbi Chronic kidney disease perspectives in Japan and the importance of urinalysis screening
    Kunihiro Yamagata
    Department of Nephrology, Institute of Clinical Medicine, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan
    Clin Exp Nephrol 12:1-8. 2008
    ..In Japan, screening with the urine dip-stick test for proteinuria has been used since 1972 targeting every child and worker ..
  44. ncbi Cross-antigenicity among EV71 strains from different genogroups isolated in Yamagata, Japan, between 1990 and 2007
    K Mizuta
    Department of Microbiology, Yamagata Prefectural Institute of Public Health, Tokamachi 1 6 6, Yamagata, 990 0031, Japan
    Vaccine 27:3153-8. 2009
    ..six subgenogroups (B2, B4, B5, C1, C2, and C4) of enterovirus 71 (EV71) between 1990 and 2007 in Yamagata, Japan. We measured neutralizing antibody (NT Ab) titers against those subgenogroup strains and the BrCr reference strain ..
  45. ncbi Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese patients with advanced non-small-cell lung cancer: results of a west Japan thoracic oncology group trial (W
    Koji Takeda
    2 13 22 Miyakojimahondohri, Miyakojima ku, Osaka 534 0021, Japan
    J Clin Oncol 28:753-60. 2010
    ..The exploratory subset analyses demonstrate a possible survival prolongation for sequential therapy of gefitinib, especially for patients with adenocarcinoma...
  46. ncbi Mental health among older adults in Japan: do sources of social support and negative interaction make a difference?
    Hideki Okabayashi
    Department of Psychology, Meisei University, 2 1 1 Hodokubo, Hino City, Tokyo 191 8506, Japan
    Soc Sci Med 59:2259-70. 2004
    ..Data for this research came from a national probability sample of 2200 persons aged 60 and over in Japan. Structural equation models were evaluated within the context of two types of social networks: (a) persons who had ..
  47. ncbi Is adenocarcinoma of the esophagogastric junction different between Japan and western countries? The incidence and clinicopathological features at a Japanese high-volume cancer center
    Shinichi Hasegawa
    Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 241 0815 Nakao 1 1 2, Asahi ku, Yokohama City, Japan
    World J Surg 33:95-103. 2009
    ..We clarified the incidence of adenocarcinoma of the esophagogastric junction (AEG) at a Japanese high-volume cancer center and its clinicopathological features between the Siewert subtypes...
  48. ncbi Vulcanisaeta distributa gen. nov., sp. nov., and Vulcanisaeta souniana sp. nov., novel hyperthermophilic, rod-shaped crenarchaeotes isolated from hot springs in Japan
    Takashi Itoh
    Japan Collection of Microorganisms, RIKEN The Institute of Physical and Chemical Research, Wako Shi, Saitama
    Int J Syst Evol Microbiol 52:1097-104. 2002
    ..heterotrophic, anaerobic, hyperthermophilic crenarchaeotes were isolated from several hot spring areas in eastern Japan, and eight representative strains were characterized further...
  49. ncbi Quality indicators of end-of-life cancer care from the bereaved family members' perspective in Japan
    Mitsunori Miyashita
    Department of Adult Nursing Palliative Care Nursing, School of Health Sciences and Nursing, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Pain Symptom Manage 37:1019-26. 2009
    ..cancer care have been conducted, the bereaved family members' perspective of QIs has not been investigated in Japan. The primary aim of this study was to rate QIs for EOL cancer care from the bereaved family members' perspective ..
  50. pmc Epidemiology of gastric cancer in Japan
    M Inoue
    Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, 5 1 1 Tsukiji, Tokyo 104 0045, Japan
    Postgrad Med J 81:419-24. 2005
    Despite its decreasing trend in Japan, gastric cancer remains an important public health problem...
  51. ncbi Detection of Anaplasma bovis and Anaplasma phagocytophilum DNA from Haemaphysalis megaspinosa in Hokkaido, Japan
    Kaoru Yoshimoto
    Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Japan
    Vet Parasitol 168:170-2. 2010
    ..flava, Ixodes ovatus and Ixodes persulcatus, collected by flagging in a pasture in Hidaka district (Hokkaido, Japan) was examined for infection with Anaplasma bovis and A. phagocytophilum by species-specific nested PCR...
  52. ncbi Social capital, income inequality and self-rated health in Chita peninsula, Japan: a multilevel analysis of older people in 25 communities
    Yukinobu Ichida
    Mitsubishi UFJ Research and Consulting Shinagawa, Japan
    Soc Sci Med 69:489-99. 2009
    ..this study aimed to investigate the linkage between social capital and health at the level of a small area in Japan, and also to examine whether social capital mediates the relation between income inequality and health...
  53. ncbi Prevalence of ulcerative colitis and Crohn's disease in Japan
    Keiko Asakura
    Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
    J Gastroenterol 44:659-65. 2009
    The prevalence of inflammatory bowel diseases is much lower in Asian countries, including Japan, than in Western countries, but it is rapidly increasing...
  54. pmc Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population
    Hirokazu Uemura
    Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Environ Health Perspect 117:568-73. 2009
    ..Environmental exposure to some persistent organic pollutants has been reported to be associated with a metabolic syndrome in the U.S. population...
  55. ncbi Gender differences in clinical confidence: a nationwide survey of resident physicians in Japan
    Kyoko Nomura
    Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan
    Acad Med 85:647-53. 2010
    The number of women physicians is increasing in Japan. The authors investigated gender differences in self-perceptions of clinical confidence.
  56. ncbi Clinical and genetic features of familial Mediterranean fever in Japan
    Ayako Tsuchiya-Suzuki
    Departments of Medicine Neurology and Rheumatology andPediatrics, Shinshu University School of Medicine, Matsumoto and theNational Center of Neurology and Psychiatry, Tokyo, Japan
    J Rheumatol 36:1671-6. 2009
    Familial Mediterranean fever (FMF) is thought to be a rare disorder in Japan, and the clinical features of Japanese patients with FMF remain unclear. Our aim was to elucidate the clinical characteristics of FMF in Japanese patients.
  57. ncbi Quality of reports on randomized controlled trials conducted in Japan: evaluation of adherence to the CONSORT statement
    Kae Uetani
    Department of Health Informatics, Kyoto University School of Public Health
    Intern Med 48:307-13. 2009
    ..We assessed the quality of current Japanese RCT reports by conducting a cross-sectional study to examine the extent to which they adhere to the CONSORT statement...
  58. ncbi Registry of 919 patients with thrombotic microangiopathies across Japan: database of Nara Medical University during 1998-2008
    Yoshihiro Fujimura
    Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan
    Intern Med 49:7-15. 2010
    ..Severe deficiency of plasma ADAMTS13 activity (ADAMTS13: AC) is more specific for TTP, but not for HUS. Since 1998, our laboratory has functioned as a nationwide referral center for TMAs by analyzing ADAMTS13...
  59. pmc A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir
    Yoko Matsuzaki
    Course of Clinical Nursing, Yamagata University Faculty of Medicine, Yamagata 990 9585, Japan
    Virol J 7:53. 2010
    ..We aimed to determine the rate of oseltamivir resistance among A(H1N1) isolates from Yamagata, Japan, to compare the virological characteristics between isolates from the 2007-2008 and 2008-2009 seasons, and to ..
  60. ncbi Long-term exposure to traffic-related air pollution and mortality in Shizuoka, Japan
    Takashi Yorifuji
    Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kita ku, Okayama City, Okayama Pref 700 8558, Japan
    Occup Environ Med 67:111-7. 2010
    ..Therefore, we evaluated the health effects of long-term exposure to traffic-related air pollution in Shizuoka, Japan.
  61. ncbi Nationwide survey on complementary and alternative medicine in cancer patients in Japan
    Ichinosuke Hyodo
    Medical Oncology Division, National Shikoku Cancer Center, Horinouchi 13, Matsuyama, 790 0007 Ehime, Japan
    J Clin Oncol 23:2645-54. 2005
    To determine the prevalence of use of complementary and alternative medicine (CAM) by patients with cancer in Japan, and to compare the characteristics of CAM users and CAM nonusers.
  62. ncbi Obesity and risk of cancer in Japan
    Shinichi Kuriyama
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan
    Int J Cancer 113:148-57. 2005
    We conducted a population-based prospective cohort study in Japan to examine the relationship between body mass index (BMI) and the risk of incidence of any cancer and of cancer at individual sites...
  63. ncbi Cause-specific mortality differences across socioeconomic position of municipalities in Japan, 1973-1977 and 1993-1998: increased importance of injury and suicide in inequality for ages under 75
    Yoshiharu Fukuda
    Health Promotion International Health, Division of Public Health, Graduate School of Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Int J Epidemiol 34:100-9. 2005
    ..This study examined socioeconomic inequality in regional mortality and the impact on inequality by cause of deaths in 1973-1977 and 1993-1998 using municipal statistics in Japan.
  64. ncbi Change in the prevalence of extended-spectrum-beta-lactamase-producing Escherichia coli in Japan by clonal spread
    Satowa Suzuki
    Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, 4 7 1 Musashi murayama, Tokyo 208 0011
    J Antimicrob Chemother 63:72-9. 2009
    In the early 2000s, there was a rapid increase in extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in hospital settings throughout Japan. The reasons for this rapid increase are unclear.
  65. ncbi The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults
    Hiroyasu Iso
    Public Health, Department of Social and Environmental Health, Osaka University and Osaka City University, Suita Shi, Osaka, Japan
    Ann Intern Med 144:554-62. 2006
    ..In western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear...
  66. ncbi Gastric cancer treatment guidelines in Japan
    Toshifusa Nakajima
    Cancer Institute Hospital, 1 37 1 Kamiikebukuro, Toshima ku, Tokyo 170 8455, Japan
    Gastric Cancer 5:1-5. 2002
    ..The Japan Gastric Cancer Association issued the first edition of Gastric cancer treatment guidelines in March, 2001 to ..
  67. ncbi Nationwide public-access defibrillation in Japan
    Tetsuhisa Kitamura
    Kyoto University Health Service, Kyoto, Japan
    N Engl J Med 362:994-1004. 2010
    ..It is unclear whether dissemination of automated external defibrillators (AEDs) in public places can improve the rate of survival among patients who have had an out-of-hospital cardiac arrest...
  68. ncbi Estimating an EQ-5D population value set: the case of Japan
    Aki Tsuchiya
    School of Health and Related Research, University of Sheffield, UK
    Health Econ 11:341-53. 2002
    ..The objectives of this study are (a) to compare the valuations obtained in Japan and Britain, and (b) to explore a local Japanese value set...
  69. ncbi Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food
    Yasuyuki Yazaki
    Center for Gastroenterology, Kobayashi Hospital, Hokkaido 090 8567, Japan
    J Gen Virol 84:2351-7. 2003
    Among ten patients who contracted sporadic acute or fulminant hepatitis E between 2001 and 2002 in Hokkaido, Japan, nine (90 %) had a history of consuming grilled or undercooked pig liver 2-8 weeks before the disease onset...
  70. ncbi Isolation of bovine arboviruses from Culicoides biting midges (Diptera: Ceratopogonidae) in southern Japan: 1985--2002
    T Yanase
    Kyushu Research Station, National Institute of Animal Health, Chuzan, Kagoshima, 891 0105 Japan
    J Med Entomol 42:63-7. 2005
    ..for bovine arboviruses was conducted in Kagoshima, located in the most southern part of the main islands of Japan and known to be an area where bovine arboviral diseases have frequently been epidemic...
  71. ncbi Randomized trial of adjuvant chemotherapy with mitomycin, Fluorouracil, and Cytosine arabinoside followed by oral Fluorouracil in serosa-negative gastric cancer: Japan Clinical Oncology Group 9206-1
    Atsushi Nashimoto
    Department of Surgery, Niigata Cancer Center Hospital, 2 15 3 Kawagishicho, Niigata 951 8566, Japan
    J Clin Oncol 21:2282-7. 2003
    ..of adjuvant chemotherapy after curative resection in serosa-negative gastric cancer patients (excluding patients who were T1N0), we conducted a multicenter phase III clinical trial in which 13 cancer centers in Japan participated.
  72. pmc Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003
    K Mizuta
    Department of Microbiology, Yamagata Prefectural Institute of Public Health, Tokamachi 1 6 6, Yamagata, 990 0031 Japan
    J Clin Microbiol 43:6171-5. 2005
    Phylogenetic analysis of 45 enterovirus 71 (EV71) isolates for 6 years in Yamagata, Japan, clarified that the annual outbreak of hand-foot-and-mouth disease was due to four genetically distinct subgenogroups, including a novel "B5...
  73. ncbi Adiponectin as a biomarker of the metabolic syndrome
    Miwa Ryo
    Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Circ J 68:975-81. 2004
    ..Adiponectin is an adipose-derived plasma protein with anti-atherogenic and insulin-sensitizing activities...
  74. ncbi Analysis of northern distribution of Aedes albopictus (Diptera: Culicidae) in Japan by geographical information system
    M Kobayashi
    Department of Medical Entomology, National Institute of Infectious Diseases, Tokyo, Japan
    J Med Entomol 39:4-11. 2002
    Aedes albopictus (Skuse), a mosquito vector of the dengue fever virus, is prevalent in Japan, distributed widely in Honshu Island with its northern limits between latitude 38 degrees to 40 degrees north...
  75. ncbi Dermatitis herpetiformis in Japan: an update
    M Shibahara
    Department of Dermatology, Tokyo Kousei Nenkin Hospital, Tokyo, Japan
    Dermatology 204:37-42. 2002
    ..We encountered a Japanese case of DH which showed granular IgA and C3 deposits in the papillary dermis and which was associated with gluten-sensitive enteropathy but no HLA-B8/DR3/DQ2...
  76. ncbi Epidemiology of sarcoidosis in Japan
    T Morimoto
    Dept of Internal Medicine, Division of Pulmonary Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyouku, Tokyo, Japan
    Eur Respir J 31:372-9. 2008
    ..phenotypes using the National Epidemiological Survey and to compare findings with those of previous surveys in Japan. Pathologically confirmed sarcoidosis cases newly diagnosed in 2004 were eligible for the present study...
  77. ncbi Fruit and vegetable intake and risk of total cancer and cardiovascular disease: Japan Public Health Center-Based Prospective Study
    Ribeka Takachi
    Department of Clinical Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Epidemiol 167:59-70. 2008
    ..16) for vegetables. This prospective cohort study demonstrated that, in the Japanese population, consumption of fruit is associated with lower risk of CVD, whereas fruit or vegetables may not be associated with lower risk of total cancer...
  78. ncbi A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARalpha transcript after consolidation therapy: the Japan Adult Leukemia Study Group (JALSG) APL97 stud
    Norio Asou
    Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan
    Blood 110:59-66. 2007
    ....
  79. ncbi Twenty-year changes in the prevalence of overweight in Japanese adults: the National Nutrition Survey 1976-95
    N Yoshiike
    National Institute of Health and Nutrition, Tokyo, Japan
    Obes Rev 3:183-90. 2002
    ..Cross-sectional annual nationwide surveys (National Nutrition Survey, Japan) were carried out with a large probability sample of the Japanese population...
  80. ncbi Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan
    Akira Ogawa
    Iwate Medical University School of Medicine, Morioka, Japan
    Stroke 38:2633-9. 2007
    The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT) Japan was organized to determine the safety and clinical efficacy of intraarterial infusion of urokinase (UK) in patients with stroke within 6 hours of onset.
  81. ncbi Metabolic syndrome and chronic kidney disease in Okinawa, Japan
    H Tanaka
    Tomishiro Chuo Hospital and Dialysis Unit, University Hospital of the Ryukyus, Okinawa, Japan
    Kidney Int 69:369-74. 2006
    We assessed the prevalence of chronic kidney disease (CKD) in a hospital-based screening program in Okinawa, Japan. The significance of metabolic syndrome as a determinant of CKD was examined using multivariate logistic regression ..
  82. ncbi Scrub typhus in Japan: epidemiology and clinical features of cases reported in 1998
    Motohiko Ogawa
    Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan
    Am J Trop Med Hyg 67:162-5. 2002
    Surveillance for scrub typhus was conducted in Japan in 1998 using a questionnaire. A total of 462 cases were reported...
  83. pmc Patterns of complementary and alternative medicine use amongst outpatients in Tokyo, Japan
    Satoshi Hori
    Department of Urology, West Suffolk Hospital, Bury St, Edmunds, UK
    BMC Complement Altern Med 8:14. 2008
    ..the patterns of CAM use, perceived effectiveness and disclosure of CAM use to orthodox medical practitioners amongst patients attending typical primary and secondary care clinics in a busy district general hospital in Tokyo, Japan.
  84. ncbi Noncancer disease incidence in atomic bomb survivors, 1958-1998
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 161:622-32. 2004
    ..These results attest to the need for continued follow-up of the aging A-bomb survivors to fully elucidate the effects of radiation exposure on the occurrence of noncancer diseases...
  85. pmc Economic recession and health inequalities in Japan: analysis with a national sample, 1986-2001
    N Kondo
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    J Epidemiol Community Health 62:869-75. 2008
    Little is known about whether economic crises widen health inequalities. Japan experienced more than 10 years of economic recession beginning in the 1990s...
  86. ncbi Amphibian chytridiomycosis in Japan: distribution, haplotypes and possible route of entry into Japan
    Koichi Goka
    National Institute for Environmental Studies, 16 2 Onogawa, Tsukuba, Ibaraki 305 8506, Japan
    Mol Ecol 18:4757-74. 2009
    A serious disease of amphibians caused by the chytrid fungus Batrachochytrium dendrobatidis was first found in Japan in December 2006 in imported pet frogs. This was the first report of chytridiomycosis in Asia...
  87. ncbi Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community: the Hisayama study
    Michiaki Kubo
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Stroke 34:2349-54. 2003
    The slowdown of a steeply declining trend in cardiovascular mortality has been reported in Japan, but precise reasons for this trend are uncertain.
  88. pmc Clinical investigation in highly disease-affected rheumatoid arthritis patients in Japan with adalimumab applying standard and general evaluation: the CHANGE study
    Nobuyuki Miyasaka
    Department of Medicine and Rheumatology, Graduate School of Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, Japan
    Mod Rheumatol 18:252-62. 2008
    ..These results and comparable ACR20 responses in Western patients support adalimumab 40 mg every other week as the appropriate dosage to treat RA in Japanese patients...
  89. ncbi History of influenza vaccination programs in Japan
    Yoshio Hirota
    Department of Public Health, Osaka City University Faculty of Medicine, 1 4 3 Asahi machi, Osaka 545 8585, Japan
    Vaccine 26:6451-4. 2008
    ..The present symposium, as part of the 9th Annual Meeting of the Japanese Society for Vaccinology in 2005, was planned to further introduce epidemiological concepts useful in studying influenza vaccine efficacy...
  90. ncbi Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 season
    Tatiana Baranovich
    Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Chuoku, Niigata City, Niigata Prefecture 951 8510, Japan
    J Clin Virol 47:23-8. 2010
    ..A substantial increase in oseltamivir-resistant A(H1N1) influenza viruses was reported in Europe in late 2007...
  91. ncbi An epidemiological survey of overactive bladder symptoms in Japan
    Yukio Homma
    Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    BJU Int 96:1314-8. 2005
    ..survey of lower urinary tract symptoms (LUTS) to determine the prevalence of overactive bladder (OAB) symptoms (defined as a symptom complex of daily urinary frequency of eight or more times and urgency once or more per week) in Japan.
  92. ncbi Bacillus cereus nosocomial infection from reused towels in Japan
    S Dohmae
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Hosp Infect 69:361-7. 2008
    ..within a hospital, with genotypes, antibiotic susceptibilities and virulence gene patterns generally distinct from those of food poisoning, and that in Japan, towels are an important source of contamination, especially in summer.
  93. pmc Bovine epizootic encephalomyelitis caused by Akabane virus in southern Japan
    Ryota Kono
    Kumamoto Central Livestock Hygiene Service Center, Shimomashiki, Kumamoto 861 3205, Japan
    BMC Vet Res 4:20. 2008
    ..A first large-scale epidemic of Akabane viral encephalomyelitis in cattle occurred in the southern part of Japan from summer to autumn in 2006...
  94. ncbi Contact lens-induced infectious keratitis in Japan
    Naoki Inoue
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Eye Contact Lens 33:65-9. 2007
    ..To identify microbiologic characteristics of infectious keratitis associated with contact lenses...
  95. ncbi Ambulatory arterial stiffness index and 24-hour ambulatory pulse pressure as predictors of mortality in Ohasama, Japan
    Masahiro Kikuya
    Tohoku University Graduate School of Medicine and Pharmaceutical Science, 1 1 Seiryomachi, Sendai, Japan
    Stroke 38:1161-6. 2007
    ..We investigated the prognostic value of AASI and PP in relation to fatal outcomes...
  96. ncbi Mortality among hemodialysis patients in Europe, Japan, and the United States: case-mix effects
    David A Goodkin
    University Renal Research and Education Association, Ann Arbor, MI 48103, USA
    Am J Kidney Dis 44:16-21. 2004
    ....
  97. pmc Population structure dynamics of Mycobacterium tuberculosis Beijing strains during past decades in Japan
    Tomotada Iwamoto
    Department of Microbiology, Kobe Institute of Health, Kobe, Japan
    J Clin Microbiol 47:3340-3. 2009
    ..the population structures of the Mycobacterium tuberculosis Beijing family between different birth-year cohorts in Japan. The results revealed that the spread of a modern sublineage that has high transmissibility is currently ..
  98. ncbi Human T-lymphotropic virus type 1 (HTLV-1) genetic typing in Kakeroma Island, an island at the crossroads of the ryukyuans and Wajin in Japan, providing further insights into the origin of the virus in Japan
    Katsuyuki Eguchi
    Department of International Health, Institute of Tropical Medicine, The Global Center of Excellence, Nagasaki University, Japan
    J Med Virol 81:1450-6. 2009
    ..samples were collected from 23 human T-lymphotropic virus type-1 (HTLV-1) carriers residing in Kakeroma Island, Japan (Kagoshima Prefecture, Oshima County, Setouchi Town), one of the most highly endemic areas in Japan...
  99. ncbi Healthy lifestyle and preventable death: findings from the Japan Collaborative Cohort (JACC) Study
    Akiko Tamakoshi
    Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan
    Prev Med 48:486-92. 2009
    ..To evaluate the effect of baseline combination of 6 lifestyle factors on all-cause mortality...
  100. ncbi High throughput screening of 16 million serologically negative blood donors for hepatitis B virus, hepatitis C virus and human immunodeficiency virus type-1 by nucleic acid amplification testing with specific and sensitive multiplex reagent in Japan
    Hideko Mine
    Japanese Red Cross Center for NAT and Quarantine, 1 31 1, Osadano, Fukuchiyama, 620 0853, Kyoto, Japan
    J Virol Methods 112:145-51. 2003
    ..This is the first automated integrated system for prevention of transfusion transmitted HBV, HCV and HIV-1 infections, by NAT screening...
  101. ncbi Low health-related quality of life is associated with all-cause mortality in patients with diabetes on haemodialysis: the Japan Dialysis Outcomes and Practice Pattern Study
    Y Hayashino
    Department of Epidemiology and Healthcare Research, Kyoto University Graduate School of Medicine, Kyoto, Japan 606 8501
    Diabet Med 26:921-7. 2009
    ..We investigated the impact of HRQoL on mortality risk in patients with diabetes on haemodialysis...

Research Grants78

  1. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2011
    ..niehs.nih.gov/. On April 27, 2009, representatives of the United States, the European Union, Canada, and Japan signed a Memorandum of Cooperation for International Cooperation on Alternative Test Methods (ICATM)...
  2. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2012
    ..niehs.nih.gov/. On April 27, 2009, representatives of the United States, the European Union, Canada, and Japan signed a Memorandum of Cooperation for International Cooperation on Alternative Test Methods (ICATM)...
  3. SPEAKER TRAVEL AND SCIENTIFIC SESSION SUPPORT FOR THE TERATOLOGY SOCIETY 50TH
    Christina Chambers; Fiscal Year: 2011
    ..Exposure to the Embryo and Child, including aspects of the 60-year follow-up study of radiation exposure in Japan during World War II...
  4. Advanced Nitric Oxide Release Bactericidal Urinary Catheters
    Mark E Meyerhoff; Fiscal Year: 2013
    ..BWTEK (Newark, DE) with offices in Japan, Germany, and China and a strong global sales team and vast experience with medical devices and laser startups, ..
  5. CHEMISTRY SUPPORT SERVICES TO THE ENVIRONMENTAL TOXICOLOGY PROGRAM
    CLARK ALGAIER; Fiscal Year: 2009
    ..ER assay international validation study chemicals were purchased, coded, and shipped to labs in Japan, Italy and USA...
  6. Depot calcineurin inhibitors to prevent graft rejection
    Thomas J Smith; Fiscal Year: 2010
    ..More than 50,000 transplants requiring immunosupression are performed annually in the largest 7 markets (US, Japan, Germany, Britain, Canada, France, Italy), and the market for immunosuppressive drugs is estimated at $2...
  7. HCV Strain Variation and HCC
    Andrea D Branch; Fiscal Year: 2012
    ..HCV is a major cause of HCC in the United States, Western Europe, and Japan and therefore it is critical to determine the molecular basis of the relationship between HCV and HCC...
  8. Evo-epidemiology of Scistosoma mansoni in children in Kenya
    ERIC SAMUEL LOKER; Fiscal Year: 2010
    ..Control (ESACIPAC) which was established at KEMRI in 2001 with the support of the Japanese Government, through the Japan International Cooperation Agency (JICA). Transmission of S...
  9. Factors Associated with Ventilator-Associated Pneumonia Guideline Adherence
    Hiroko Kiyoshi-Teo; Fiscal Year: 2011
    ..In the future, I hope to expand my studies internationally especially between the US and Japan as 1 have both the educational and clinical experience, as well as strong connections with both countries...
  10. 16th ISBRA Conference
    Edward P Riley; Fiscal Year: 2012
    ..and since the founding of ISBRA, meetings have been held in Australia, Canada, Denmark, Finland, France, Germany, Japan, United Kingdom, and the United States. For the 16th Congress in 2012, ISBRA will be meeting in Sapporo, Japan...
  11. 6th Orthomyxovirus Research Conference
    STACEY L SCHULTZ-CHERRY; Fiscal Year: 2012
    ..S., Russia, Japan, and many other parts of the world...
  12. Role of a new polyomavirus in Merkel cell carcinoma
    Patrick S Moore; Fiscal Year: 2013
    ..Human serosurveys show that 15-30% of populations from the US, Japan and Germany have cross-reactive antibodies to LPV which may actually represent reactivity to MCPyV infection...
  13. Epidemiology of CHD of Men Aged 40+ in US, Hawaii, Japan
    Akira Sekikawa; Fiscal Year: 2012
    Coronary heart disease (CHD) is the single largest killer for both men and women in the US. The Japanese in Japan continue to have very low CHD rates despite increasing levels of risk factors since the end of World War II (WWII)...
  14. Health and Retirement Survey for India
    David Bloom; Fiscal Year: 2009
    ..will provide new research opportunities for researchers in the United States and in Asian countries such as China, Japan, and Korea that have comparable HRS-type surveys...
  15. Molecular Basis of Autosomal Dominant Hypercholesterolemia in a Multiethnic Cohor
    Zahid Ahmad; Fiscal Year: 2013
    ..Most of these studies were performed in ethnically and racially homogenous populations from Europe or Japan. Thus, there is paucity of data about the molecular basis of ADH in multi-ethnic cohorts, especially African ..
  16. Genetics of Elevated High Density Lipoprotein Cholesterol
    DANIEL JAMES RADER; Fiscal Year: 2012
    ..is homozygous cholesteryl ester transfer protein (CETP) deficiency, which is found almost exclusively in Japan and led to the concept of pharmacologic CETP inhibition as a strategy to raise HDL-C levels...
  17. EHEC-induced actin rearrangement and Stx2 translocation across epithelium
    John M Leong; Fiscal Year: 2012
    ..Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important food-borne pathogen in North America, Europe and Japan (79)...
  18. Strategies for Heavy Metal Detoxification
    Gerard Parkin; Fiscal Year: 2013
    ..in particular, are highly toxic as illustrated by the death of almost two thousand people around Minamata Bay (Japan) in the late 1950s when the residents consumed fish that were contaminated with methyl mercury compounds...
  19. Serum microRNA as biomarker for radiation injury to lung and hematopoietic cells
    Dipanjan Chowdhury; Fiscal Year: 2013
    ..in terrorist events, industrial accidents or natural disasters (such as the nuclear disaster after the tsunami in Japan) is a current and continuing threat for the future...
  20. 16th international conference on Campylobacter, Helicobacter and related organism
    Irving Nachamkin; Fiscal Year: 2011
    ..Marshall remains very active with CHRO meetings and gave a keynote address at the past CHRO meeting in Niigata, Japan in 2009...
  21. HDAC Inhibitors Inspired by Natural Products
    Dennis L Wright; Fiscal Year: 2012
    ..from taiwanhinoki (Chamaecyparis taiwanesis) and Japanese hinoki (Chamaecyparis obtuse) have been prized in Japan and China...
  22. The Complexity of Immigrant Generations
    STEPHEN J TREJO; Fiscal Year: 2010
    ..groups from Hispanic (Mexico, Puerto Rico, Cuba, El Salvador, and the Dominican Republic) and Asian (China, India, Japan, Korea, and the Philippines) source countries...
  23. Feasibility, benefits, and acceptability of lowering the BAC standard in the US
    David W Eby; Fiscal Year: 2013
    ..that have been reported in other countries that have implemented a lowering of the legal BAC level, such as Japan, many European countries, and Australia...
  24. Demography of Sex Differences in Health and Survival
    James W Vaupel; Fiscal Year: 2013
    ..and register data on humans in Denmark (Project 2); Survey data on humans in the United States (Project 3) and in Japan, the Philippines and Singapore (Project 4); Longitudinal observations on baboons in the wild in Kenya (Project 5); ..
  25. XV International Conference on Human Retrovirology: HTLV and Related Viruses
    Edward L Murphy; Fiscal Year: 2011
    ..the meeting has been held in HTLV-endemic areas such as Hawaii, Jamaica, Trinidad, Brazil, and southeastern Japan, or at international research centers such as Paris, Dublin and San Francisco...
  26. Metabolomics-Measured Urinary Metabolites, Diet and BP, 17 Random Samples
    LINDA VERNER VAN HORN; Fiscal Year: 2013
    ..already in hand on the 4,630 INTERMAP participants (women and men ages 40-59 from 17 population samples - - 4 in Japan;3, People's Republic of China;2, UK;8, USA)...
  27. Effects of Methylmercury on Neuronal Cell Migration
    Hitoshi Komuro; Fiscal Year: 2010
    ..In the tragic disasters that took place at Minamata, Japan, and subsequently in Iraq, many infants were exposed transplacentally to MeHg...
  28. Helicobacter pylori blood biomarker for gastric cancer risk in East Asia
    Meira Epplein; Fiscal Year: 2013
    ..a consortium of eight prospective cohort studies in the high gastric cancer-incidence populations of China, Japan, and Korea, to determine if we can replicate this novel biomarker panel for gastric cancer risk...
  29. International Population Study on Macronutrients and BP - INTERMAP
    LINDA VERNER VAN HORN; Fiscal Year: 2013
    ..women ages 40-59 from 17 population samples of diverse ethnicity/ SES/ eating practices in four countries (China, Japan, UK, USA)...
  30. Travel Awards for the 11th International Conference on Environmental Mutagens
    THOMAS EDWARD WILSON; Fiscal Year: 2013
    ..Leona Samson, USA;Fabrizio D'Adda di Fagagna, Italy;Alan Lehman, UK;Jean Marc Egly, France;Hiroshi Kasai, Japan;Thomas Kunkel, USA;Wei Yang, USA;Michael Fenech, Australia, Alain Sarasin, France and Stefano Bonassi, Italy...
  31. Phase III infliximab for primary treatment of Kawasaki disease IND 11046 6/27/200
    Jane C Burns; Fiscal Year: 2012
    ..S. and Japan (Taubert et al. 1991). There are approximately 126,000 affected children in the U.S...
  32. Mechanics of Hearing Workshop
    KIRIAKI DOMENICA KARAVITAKI; Fiscal Year: 2013
    ..Previous Workshops were held in the Netherlands, United Kingdom, Japan, Germany and United States...
  33. TUMOR-TARGETING WITH NEW BORONATED PORPHYRINS
    MARIA DA GRACA HENRIQUES VICENTE; Fiscal Year: 2010
    ..Phase I/II BNCT clinical trials are being pursued in the U.S., Europe, and Japan, for the treatment of patients with glioblastomas and melanomas;although there is clear evidence of a therapeutic ..
  34. Impact of TNFa blockade on immune function in acute Kawasaki disease
    ALESSANDRA I FRANCO; Fiscal Year: 2013
    ..of unknown etiology that is the leading cause of acquired heart disease in children in the United States and Japan. Although the acute illness resolves spontaneously, permanent damage to the coronary arteries occurs in 20-25% of ..
  35. Aging, Social Interdependence and Wisdom in the U.S. and Japan
    Richard E Nisbett; Fiscal Year: 2010
    ..We will draw random samples from one middle-class area and one working-class area of both the United States and Japan. We will measure health, socioeconomic status, crystallized intelligence and fluid intelligence...
  36. MOLECULAR GENETICS OF ENTEROPATHOGENIC E. COLI ADHESION
    James B Kaper; Fiscal Year: 2013
    ..S., Finland, and Japan. Recent studies of atypical EPEC in children with diarrhea in the U.S...
  37. White Matter Protection in Acute Ischemic Stroke
    Chia Yi Kuan; Fiscal Year: 2012
    ..blood- brain-barrier-permeable free radical scavenger already approved for treating acute ischemic stroke in Japan, but its effects on WM protection are yet to be examined...
  38. Organophosphate Action in the Central Nervous System
    NEIL MARC NATHANSON; Fiscal Year: 2012
    ..dangers of the use of OP nerve agents in attacks on civilian populations was demonstrated by the sarin attacks in Japan in 1994 and 1995 which resulted not only in immediate deaths but in changes in long-lasting neurological functions...
  39. FASEB SRC on Regulation and Function of Small GTPases
    KAREN M CICHOWSKI; Fiscal Year: 2013
    ..There are 35 invited speakers from the United States, Europe, Singapore and Japan (all of which are confirmed)...
  40. Functional characterization of Orientia tsutsugamushi ankryin repeat proteins
    Jason A Carlyon; Fiscal Year: 2013
    ..A recent outbreak among U.S. Marines training at a military base in Japan, and the prevalence of scrub typhus in Afghanistan and Pakistan where U.S...
  41. Maternal Methylmercury Exposure Through Rice Ingestion and Offspring Development
    SARAH ROTHENBERG; Fiscal Year: 2013
    ..Historical methylmercury poisonings in Japan and Iraq confirmed human health impacts from methylmercury exposure were most severe in the developing fetus due ..
  42. HTLV-1 Particle Analysis and Gag Interactions
    Louis M Mansky; Fiscal Year: 2013
    ..HTLV-1 infection in the general population are greater than 1% in the Caribbean Basin, Central Africa, and South Japan. HTLV-1 is notorious for being difficult to study in cell culture, which ha prohibited a rigorous analysis of how ..
  43. CHRONOBIOLOGIC MARKERS FOR LAB MEDICINE AND THERAPY
    Franz Halberg; Fiscal Year: 2012
    ..Monitoring continued at all participating centers. In particular, citizens of Urausu and Tosa, Japan, where the awardee was invited to lecture this year, are being screened with additional focus on several indices ..
  44. Cross-cultural neuroimaging of emotion in South Africa, Japan and US
    Joan Y Chiao; Fiscal Year: 2013
    ..g., US) compared to non-Western cultures (e.g., Japan and South Africa)...
  45. TP508: A New Drug for Mitigating Lethal Effects of Radiatin Exposure
    Laurie E Sower; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): With recent radiation release from reactors in Japan and increasing probability of nuclear detonation somewhere in the world, there is a critical need for development of effective medicinal counter-..
  46. Alcoholism and Stress: A Framework for Future Treatment Strategies
    Marisa Roberto; Fiscal Year: 2013
    ..following countries: Russia, Australia, Austria, Belgium, Canada, China, Finland, France, Germany, Greece, Italy, Japan, Spain, Sweden, Switzerland, United Kingdom, and the United States...
  47. Early Detection of Pervasive Developmental Disorders
    Deborah A Fein; Fiscal Year: 2013
    ..which is now widely used in the US, and is being studied in translation in other countries and cultures, including Japan, China, Spain, the Netherlands, France, Iceland, Ireland, Germany, Egypt, Puerto Rico and Turkey...
  48. International Symposium on ALPD and Cirrhosis
    Hidekazu Tsukamoto; Fiscal Year: 2013
    ..The 6th~8th symposia will be held in Fukuoka, Japan in 2011, in Beijing, China in 2012, and Deli, India in 2013, and their organizers have been selected...
  49. Novel Rho Kinase Inhibitor for Systemic Sclerosis
    Susan C Wright; Fiscal Year: 2013
    ..Rho kinase inhibitors such as fasudil (approved in Japan for cerebral vasospasm) have proven effective in various preclinical models of fibrosis and inflammation;however ..
  50. CRCNS: Cerebellar cortico-nuclear interactions
    Dieter Jaeger; Fiscal Year: 2013
    ..Course in Computational Neuroscience (LASCON, Brazil), and the Okinawa Course in Computational Neuroscience (OCNC, Japan)...
  51. EGFR Mutations in non-Small Cell Lung Cancer
    Bruce E Johnson; Fiscal Year: 2013
    ..Subsequent clinical studies done in Japan, China, East Asia, and Europe showed NSCLC patients with EGFR mutations treated with gefitinib or erlotinib have a ..
  52. Integration of phenotype data from multiple centers using ontologies
    Melinda R Dwinell; Fiscal Year: 2012
    ..of Hypertension, the PhysGen Program for Genomic Applications, and the National BioResource Project for the Rat in Japan, ontologies will be developed for the four major experimental parameters common to rat phenotype data: 1) clinical ..
  53. Case-PNG Global Infectious Disease Research Training Program (D43)
    Peter A Zimmerman; Fiscal Year: 2013
    ..has been demonstrated as 8 of these BSc honors graduates have secured funding to pursue Masters Degrees in Europe, Japan, Australia and the United States...
  54. In Vivo Detection of Flat Colorectal Neoplasms with CT Colonography
    JANNE JOHANNES NAPPI; Fiscal Year: 2010
    ..Until recently, non-polypoid lesions were thought to be rare outside Japan, where they are reported relatively often on state-of-the-art optical colonoscopy (OC) examinations...
  55. Mechanisms of immunomodulatory and anti-tumor actions of Polysaccharide Krestin
    Mary L Disis; Fiscal Year: 2010
    Mushroom extracts have long been used in Asia as immunopotentiating agents. Many studies, mostly conducted in Japan and China, have shown that ingestion of mushroom extracts can induce tumor regression or stabilization in both animal ..
  56. Pathway Dependence on Tyrosine Kinase TYK2 in T-cell Acute Lymphoblastic Leukemia
    Takaomi Sanda; Fiscal Year: 2012
    ..Building on Dr. Sanda's medical and scientific training in Japan, he has uncovered and is now defining the role of tyrosine kinases in the proliferation and survival of cancer/..
  57. Regulation of immune reactions by synthetic thioglucans
    Vaclav Vetvicka; Fiscal Year: 2010
    ..a well-known biological response modifier that has been used as adjuvant therapy for cancer since 1980, mostly in Japan. b-Glucans also enhance innate host defense against certain bacteria, yeast, and viral pathogens...
  58. The Health Burden of A Recently Discovered Borrelia Spirochete
    PETER JAMES KRAUSE; Fiscal Year: 2012
    ..of a closely related group of relapsing fever spirochetes and was originally described as Borrelia miyamotoi in Japan. Recent investigations provide convincing evidence that this spirochete causes human disease in Russia where the ..
  59. Comparative effects of resistance training protocols in older adults at risk of m
    Summer B Cook; Fiscal Year: 2012
    ..This type of resistance exercise is regularly performed in Japan, where it is referred to as KAATSU (meaning literally: strength training "with the addition of pressure")...
  60. 12th International Congress of Radiation Research
    George Iliakis; Fiscal Year: 2003
    ..in Great Britain, several countries in Europe (the Netherlands, Sweden, Poland, Germany, Italy, and France), Japan, and Israel...
  61. Polyphenon E for the Chemoprevention of Colorectal Cancer
    Frank A Sinicrope; Fiscal Year: 2013
    ..COX inhibitor sulindac was shown to regress rectal ACF in high risk patients in a small, open- label trial from Japan. ACF consist of enlarged and thickened crypts that can be detected in human colorectal mucosa using magnifying ..
  62. 11TH INTERNATIONAL CONGRESS OF RADIATION RESEARCH
    Elizabeth Travis; Fiscal Year: 1999
    ..in Great Britain, several countries in Europe (the Netherlands, Sweden, Poland, Germany, Italy and France), Japan, and Israel...
  63. NKT Cells Immunotherapy: Targeting Dendritic Cells with Glycolipid Liposomes
    Peng Wang; Fiscal Year: 2007
    ..objective response has been found in several clinical trials conducted by different teams in the United States, Japan and Europe...
  64. INTRACAVITARY HYPERTHERM & RADIATN OF ESOPHAGEAL CANCER
    C Chou; Fiscal Year: 1993
    ..Recent clinical reports from China and Japan show much improved tumor response and survival rate in patients treated with combined hyperthermia and external ..
  65. Low-cost Large-area High-Sensitivity X-ray Panel Detector for Digital Mammography
    NEAL EUGENE HARTSOUGH; Fiscal Year: 2010
    ..Recently, academic research groups in Korea and Japan have investigated the potential for polycrystalline CZT films grown directly onto readouts to create x-ray imaging ..
  66. Economic Restructuring and Social Mobility in Japan
    Wei hsin Yu; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Since the burst of its "bubble" economy in 1989, Japan has experienced an astonishingly long and severe economic recession, featuring just 1.3% average real growth per year between 1990 and 2005...
  67. AMINO ACIDS IN URINE, DIET & BP: INT'L POPULATION STUDY
    Martha Daviglus; Fiscal Year: 2003
    ..S., U.K., China, Japan)...
  68. Novel Treatment for Degenerative Myopia
    JULIA KORNFIELD; Fiscal Year: 2009
    ..Indeed, degenerative myopia is the leading cause of untreatable blindness in China, Taiwan, and Japan, and is ranked 7th in the United States...
  69. CDP-choline: Mechanisms in Cerebral Ischemia
    RAO ADIBHATLA; Fiscal Year: 2006
    Significance and goal: CDP-choline (citicoline) stroke clinical trials in Europe and Japan showed significant improvement, while US studies provided ambiguous results...
  70. US-China-Japan Research Consortium on Herbal Medicines
    David Eisenberg; Fiscal Year: 2004
    ..the China Academy of Traditional Chinese Medicine, the Chinese University of Hong Kong, and Keio University (Japan) to jointly identify and prioritize promising herbal medicines, which can be systematically procured, extracted, ..
  71. ORAL-FACIAL CLEFTS IN CHINA
    Michael Melnick; Fiscal Year: 1990
    ..For CL+-P, Orientals are at higher risk than Caucasians or Blacks. Although some studies have been reported from Japan, they are analytically quite limited and most inconclusive...
  72. BORON NEUTRON CAPTURE THERAPY OF OCULAR MELANOMA
    Samuel Packer; Fiscal Year: 1992
    ..in the treatment of rabbit eye tumors, and also when compared to Na2B12H11SH(BSH) currently being used in Japan to treat brain tumors. BPA is currently being used clinically to treat subcutaneous melanomas in Japan...
  73. DEATH RATES AND DEATH DATA FOR ASIAN AMERICAN ELDERLY
    Diane Lauderdale; Fiscal Year: 2003
    ..those for any other race category - less than two-thirds of white rates, and are also lower than death rates in Japan, the country with highest life expectancy...
  74. The role of Pak1 in regulating plexiform neurofibroma formation
    Andrew McDaniel; Fiscal Year: 2009
    ..NF1 is a common, pandemic, inherited disease that affects over 200,000 patients in North America, Europe, and Japan alone...
  75. EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
    Eric Larson; Fiscal Year: 2000
    Existing studies suggest that, while the overall prevalence rates of dementia in Japan and the U.S. are similar, the relative prevalence of Alzheimer's disease (AD) to vascular dementia (VaD) is much greater in the U.S...
  76. International Workshops on Iron and Copper Homeostasis
    Michael Garrick; Fiscal Year: 2004
    ..for funds, is a similar number of foreign scientists, from Latin America, Europe, Canada, Israel, Australia and Japan and a larger number of foreign pre- and post-doctoral students. The workshop organizers are Dr...
  77. TENTH CONGRESS: INT SOC. BIOMED. RES. ALCOHOLISM
    Ting Kai Li; Fiscal Year: 2000
    ..This meeting will be held in Yokohama, Japan, July 2-8, 2000...
  78. Type I Diabetes Model in Zebrafish
    Meera Saxena; Fiscal Year: 2009
    ..S., India, China, Russia, and Japan is already spiraling out of control...