Genomes and Genes
Summary: A republic in eastern Africa, south of ETHIOPIA and east of SOMALIA. Its capital is Nairobi. The region was organized as the British East Africa Protectorate in 1895, became a British colony in 1920, became independent in 1963, and became a republic in 1964. It took its name from Mount Kenya which probably meant simply mountain. (From Webster's New Geographical Dictionary, 1988, p601 & Room, Brewer's Dictionary of Names, 1992, p282)
Publications367 found, 100 shown here
- Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trialRobert C Bailey
Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, IL 60612, USA
Lancet 369:643-56. 2007..Our aim was to determine whether male circumcision had a protective effect against HIV infection, and to assess safety and changes in sexual behaviour related to this intervention...
- Anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western Nyanza Province, KenyaM Nabie Bayoh
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, 48824, USA
Malar J 9:62. 2010..bed nets in Asembo and low coverage in Seme, two adjacent communities in western Nyanza Province, Kenya; followed by expanded coverage of bed nets in Seme, as the Kenya national malaria programme rolled out; provided a ..
- Bacteremia among children admitted to a rural hospital in KenyaJames A Berkley
Centre for Geographic Medicine Research Coast, Kilifi, Kenya
N Engl J Med 352:39-47. 2005..We studied every acute pediatric admission to a rural district hospital in Kenya to examine the prevalence, incidence, types, and outcome of community-acquired bacteremia.
- Association between climate variability and malaria epidemics in the East African highlandsGuofa Zhou
Department of Biological Sciences, State University of New York, Buffalo, NY 14260, USA
Proc Natl Acad Sci U S A 101:2375-80. 2004....
- Spatial and temporal heterogeneity of Anopheles mosquitoes and Plasmodium falciparum transmission along the Kenyan coastCharles M Mbogo
Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
Am J Trop Med Hyg 68:734-42. 2003..parasites were studied for one year at 30 villages in Malindi, Kilifi, and Kwale Districts along the coast of Kenya. Anopheline mosquitoes were sampled inside houses at each site once every two months and malaria parasite ..
- Integrated malaria vector control with microbial larvicides and insecticide-treated nets in western Kenya: a controlled trialUlrike Fillinger
Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, England
Bull World Health Organ 87:655-65. 2009....
- Active convulsive epilepsy in a rural district of Kenya: a study of prevalence and possible risk factorsTansy Edwards
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
Lancet Neurol 7:50-6. 2008..We aimed to estimate the prevalence of, treatment gap in, and possible risk factors for active convulsive epilepsy in Kenyan people aged 6 years or older living in a rural area...
- Understanding of informed consent in a low-income setting: three case studies from the Kenyan CoastC S Molyneux
Kenya Medical Research Institute, PO Box 230, Kilifi, Kenya
Soc Sci Med 59:2547-59. 2004..These themes and emerging recommendations are expected to be relevant to, and would benefit from, experiences and insights of researchers working elsewhere...
- Chloroquine resistance before and after its withdrawal in KenyaLeah Mwai
Kenya Medical Research Institute Wellcome Trust Collaborative Research Programme, Kilifi, Kenya
Malar J 8:106. 2009..the polymorphisms of markers associated with CQ-resistance against Plasmodium falciparum isolates from coastal Kenya (Kilifi) were investigated, from 1993, prior to the withdrawal of CQ, to 2006, seven years after its withdrawal...
- Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malariaP C Bull
Kenya Medical Research Institute CRC, Kilifi Unit
Nat Med 4:358-60. 1998..The apparent selective pressure exerted by established anti-PfEMP1 antibodies on infecting parasites supports the idea that such responses provide variant-specific protection against disease...
- Sampling outdoor, resting Anopheles gambiae and other mosquitoes (Diptera: Culicidae) in western Kenya with clay potsM Odiere
Vector Biology and Control Research Centre, Kenya Medical Research Institute, Kisumu, Kenya
J Med Entomol 44:14-22. 2007..resting fraction of Anopheles gambiae Giles (Diptera: Culicidae) and other mosquito species in a rural, western Kenya. Clay pots (Anopheles gambiae resting pots, herein AgREPOTs), outdoor pit shelters, indoor pyrethrum spray ..
- Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trialJacek Skarbinski
Malaria Branch, US Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Am J Trop Med Hyg 80:919-26. 2009Shortly after Kenya introduced artemether-lumefantrine (AL) for first-line treatment of uncomplicated malaria, we conducted a pre-post cluster randomized controlled trial to assess the effect of providing malaria rapid diagnostic tests (..
- Effects of micro-enterprise services on HIV risk behaviour among female sex workers in Kenya's urban slumsWillis Omondi Odek
Department of Community Health, University of Nairobi, P O Box 1086, City Square 00200, Nairobi, Kenya
AIDS Behav 13:449-61. 2009..adding micro-enterprise services to a peer-mediated HIV/AIDS intervention among 227 female sex workers (FSWs) in Kenya. Survey data were collected in May-July 2003 and July-August 2005...
- Female sex workers and unsafe sex in urban and rural Nyanza, Kenya: regular partners may contribute more to HIV transmission than clientsH A C M Voeten
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands
Trop Med Int Health 12:174-82. 2007To compare the sexual behaviour of female sex workers in urban and rural areas in Nyanza province in Kenya, and to compare their unsafe sex with clients and with regular partners.
- Provision and use of maternal health services among urban poor women in Kenya: what do we know and what can we do?Jean Christophe Fotso
Population Dynamics and Reproductive Health, African Population and Health Research Center APHRC, Nairobi, Kenya
J Urban Health 85:428-42. 2008..study uses a unique combination of health facility- and individual-level data collected in the slums of Nairobi, Kenya to: (1) describe the provision of obstetric care in the Nairobi informal settlements; (2) describe the patterns of ..
- Impact of five years of peer-mediated interventions on sexual behavior and sexually transmitted infections among female sex workers in Mombasa, KenyaStanley Luchters
International Centre for Reproductive Health, Mombasa, Kenya
BMC Public Health 8:143. 2008Since 2000, peer-mediated interventions among female sex workers (FSW) in Mombasa Kenya have promoted behavioural change through improving knowledge, attitudes and awareness of HIV serostatus, and aimed to prevent HIV and other sexually ..
- Health and demographic surveillance in rural western Kenya: a platform for evaluating interventions to reduce morbidity and mortality from infectious diseasesKubaje Adazu
Centers for Disease Control and Prevention Kenya Program, Nairobi, Kenya
Am J Trop Med Hyg 73:1151-8. 2005We established a health and demographic surveillance system in a rural area of western Kenya to measure the burden of infectious diseases and evaluate public health interventions...
- Treatment-seeking behaviour, cost burdens and coping strategies among rural and urban households in Coastal Kenya: an equity analysisJane Chuma
Kenya Medical Research Institute, Kilifi, Kenya
Trop Med Int Health 12:673-86. 2007....
- Translation of artemether-lumefantrine treatment policy into paediatric clinical practice: an early experience from KenyaD Zurovac
Malaria Public Health and Epidemiology Group, KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
Trop Med Int Health 13:99-107. 2008To describe the quality of outpatient paediatric malaria case-management approximately 4-6 months after artemether-lumefantrine (AL) replaced sulfadoxine-pyrimethamine (SP) as the nationally recommended first-line therapy in Kenya.
- Malaria drug shortages in Kenya: a major failure to provide access to effective treatmentBeth B Kangwana
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Programme Nairobi, Kenya
Am J Trop Med Hyg 80:737-8. 2009..Two years after artemether-lumefathrine (AL) was introduced for the management of uncomplicated malaria in Kenya, we carried out a cross-sectional survey to investigate AL availability in government facilities in seven malaria-..
- HIV prevalence and associated risk factors among individuals aged 13-34 years in Rural Western KenyaPauli N Amornkul
Division of HIV AIDS Prevention, US Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 4:e6470. 2009To estimate HIV prevalence and characterize risk factors among young adults in Asembo, rural western Kenya.
- Both heterozygous and homozygous alpha+ thalassemias protect against severe and fatal Plasmodium falciparum malaria on the coast of KenyaThomas N Williams
Wellcome Trust Kenya Medical Research Institute KEMRI, Centre for Geographic Medicine Research, Kilifi, Kenya
Blood 106:368-71. 2005..Our study supports the conclusion that both heterozygotes and homozygotes enjoy a selective advantage against death from Plasmodium falciparum malaria...
- Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malariaSpencer D Polley
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Vaccine 23:718-28. 2004..Results encourage the development of an AMA1 vaccine based on the full-length ectodomain, and indicate that the function of human antibodies to allele-specific and conserved epitopes in AMA1 should be studied further...
- Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western KenyaSimon Brooker
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 9:757-66. 2004..Active case surveillance was undertaken in three schools in Nandi District, Western Kenya for 10 weeks during a malaria outbreak in May-July 2002...
- Three kinds of psychological determinants for hand-washing behaviour in KenyaRobert Aunger
London School of Hygiene and Tropical Medicine, ITD, Keppel Street, London, United Kingdom
Soc Sci Med 70:383-91. 2010..We suggest that those developing hygiene promotion programmes should consider the possible existence of multiple types of strategies for increasing hand-washing behaviour...
- Prevalence, incidence and risk factors of epilepsy in older children in rural KenyaV Mung'ala-Odera
Center for Geographic Medicine Research Coast, Kenya Medical Research Institute, PO Box 428 80108, Bofa Road, Kilifi, Kenya
Seizure 17:396-404. 2008..There is little data on the burden or causes of epilepsy in developing countries, particularly in children living in sub-Saharan Africa...
- Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparumJ Teun Bousema
Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
J Infect Dis 193:1151-9. 2006....
- The acceptability of male circumcision to reduce HIV infections in Nyanza Province, KenyaR C Bailey
School of Public Health, University of Illinois at Chicago, USA
AIDS Care 14:27-40. 2002..the acceptability of male circumcision in the Luo, a large, traditionally non-circumcising ethnic group in western Kenya. Separate focused group discussions with adult Luo men and women and semi-structured interviews with clinicians ..
- Human immunodeficiency virus (HIV) type 1 proviral hypermutation correlates with CD4 count in HIV-infected women from KenyaAllison M Land
Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba R3E 0W3, Canada
J Virol 82:8172-82. 2008..During HIV-1 sequence analysis of the vpu/env region of 240 HIV-infected subjects from Nairobi, Kenya, 13 drastically hypermutated proviral sequences were identified...
- The impact of distance of residence from a peripheral health facility on pediatric health utilisation in rural western KenyaDaniel R Feikin
Kenya Medical Research Institute KEMRI, Kisumu, Kenya
Trop Med Int Health 14:54-61. 2009To explore the impact of distance on utilisation of peripheral health facilities for sick child visits in Asembo, rural western Kenya.
- Association between land cover and habitat productivity of malaria vectors in western Kenyan highlandsStephen Munga
Kenya Medical Research Institute, Kisumu, Kenya
Am J Trop Med Hyg 74:69-75. 2006..gambiae larvae, and consequently increase the risks of malaria transmission to the human population...
- Characteristics of larval anopheline (Diptera: Culicidae) habitats in Western KenyaJ E Gimnig
Kenya Medical Research Institute, Centre for Vector Biology and Control Research, Kisumu
J Med Entomol 38:282-8. 2001A longitudinal survey of mosquito larval habitats was carried out in Asembo Bay, western Kenya, during the rainy season of 1998. All pools of standing water along a 700-m transect were sampled twice per week...
- The risks of malaria infection in Kenya in 2009Abdisalan M Noor
Centre for Geographic Medicine, KEMRI University of Oxford, Kenyatta National Hospital Grounds, Nairobi, Kenya
BMC Infect Dis 9:180. 2009..Here we present a new map of malaria risk for Kenya in 2009.
- Malaria paediatric hospitalization between 1999 and 2008 across KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
BMC Med 7:75. 2009..Here we present a nationwide assessment of changes over 10 years in paediatric malaria hospitalization across Kenya.
- Feasibility, acceptability and cost of home-based HIV testing in rural KenyaJoel Negin
School of Public Health, University of Sydney, Sydney, Australia
Trop Med Int Health 14:849-55. 2009..To demonstrate the feasibility, acceptability and cost of home-based HIV testing and to examine the applicability of the model to high HIV prevalence settings...
- House design modifications reduce indoor resting malaria vector densities in rice irrigation scheme area in western KenyaHarrysone Atieli
Kenya Medical Research Institute, Kisumu, Kenya
Malar J 8:108. 2009..A randomized-controlled study was, therefore, undertaken to determine the effects of this method of vector control on the density of indoor resting malaria vectors in a rice irrigation scheme area in lowlands of western Kenya.
- Safer sexual behaviors after 12 months of antiretroviral treatment in Mombasa, Kenya: a prospective cohortStanley Luchters
International Centre for Reproductive Health, Mombasa, Kenya, International Centre for Reproductive Health, Ghent University, Ghent, Belgium
AIDS Patient Care STDS 22:587-94. 2008..Positive prevention interventions for those receiving ART must reinforce safer sex practices and partner disclosure...
- Sexual risk behaviour and HAART: a comparative study of HIV-infected persons on HAART and on preventive therapy in KenyaA Sarna
Population Council, India Habitat Centre, New Delhi, India
Int J STD AIDS 19:85-9. 2008..with that of 143 PLHA receiving preventive therapy (PT) with cotrimoxazole/isoniazid was conducted in Mombasa, Kenya. Forty-five percent of all participants were sexually active in the last six months...
- Extending social health insurance to the informal sector in Kenya. An assessment of factors affecting demandInke Mathauer
Department of Health Systems Financing, World Health Organization, 1211 Geneva 27, Switzerland
Int J Health Plann Manage 23:51-68. 2008..contributes to analysing and understanding the demand for (social) health insurance of informal sector workers in Kenya by assessing their perceptions and knowledge of and concerns regarding health insurance and the Kenyan National ..
- Acceptability of male circumcision and predictors of circumcision preference among men and women in Nyanza Province, KenyaC L Mattson
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, 1603 W Taylor Street, Chicago, IL 60612, USA
AIDS Care 17:182-94. 2005..This cross-sectional survey of 107 men and 110 women in Nyanza Province, Kenya, assesses the attitudes, beliefs, and predictors of circumcision preference among men and women in a traditionally ..
- Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodiesKristina E M Persson
The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
J Clin Invest 118:342-51. 2008..falciparum and that a broad inhibitory response against multiple ligands may be required for effective immunity...
- Comparing bleaching and mortality responses of hard corals between southern Kenya and the Great Barrier Reef, AustraliaT R McClanahan
The Wildlife Conservation Society, P O Box 99470, Mombasa, Kenya
Mar Pollut Bull 48:327-35. 2004..taxa in different sites at the same depth produced high correlation coefficients in the bleaching response in Kenya at 2 m (r=0.86) and GBR at 6 m depth sites (r=0.80) but less in the GBR for shallow 2 m sites (r=0.49)...
- What does access to maternal care mean among the urban poor? Factors associated with use of appropriate maternal health services in the slum settlements of Nairobi, KenyaJean Christophe Fotso
African Population and Health Research Center APHRC, P O Box 10787, 00100 GPO, Nairobi, Kenya
Matern Child Health J 13:130-7. 2009..The objective of this paper is to identify the factors which influence the choice of place of delivery among the urban poor, with a distinction between sub-standard and "appropriate" health facilities...
- Effects of microclimatic changes caused by deforestation on the survivorship and reproductive fitness of Anopheles gambiae in western Kenya highlandsYaw A Afrane
Climate and Human Health Research Unit, Centre for Vector Biology and Control Research, Kenya Medical Research Institute, Kenya
Am J Trop Med Hyg 74:772-8. 2006..on the survivorship and reproductive fitness of Anopheles gambiae in an epidemic prone area in the western Kenya highlands. We found that the mean indoor temperatures of houses located in the deforested area were 1...
- Risk of severe malaria among African infants: direct evidence of clinical protection during early infancyR W Snow
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Nairobi, Kenya
J Infect Dis 177:819-22. 1998....
- Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in KenyaMike English
KEMRI Centre for Geographic Medicine Research, PO Box 230, Kilifi, Kenya
Lancet 363:1948-53. 2004The district hospital is considered essential for delivering basic, cost-effective health care to children in resource poor countries. We aimed to investigate the performance of these facilities in Kenya.
- Community-wide benefits of targeted indoor residual spray for malaria control in the western Kenya highlandGuofa Zhou
Program in Public Health, College of Health Sciences, University of California, Irvine, CA 92697 4050, USA
Malar J 9:67. 2010..Where malaria transmission is concentrated around focal points, however, targeted IRS may pose a feasible alternative to mass spraying. Here, the impact of targeted IRS was assessed in the highlands of western Kenya.
- The decline in paediatric malaria admissions on the coast of KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P, O, Box 43640, 00100 GPO, Nairobi, Kenya
Malar J 6:151. 2007..There is only limited information on the health impact of expanded coverage of malaria control and preventative strategies in Africa...
- An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98Christopher W Woods
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 8:138-44. 2002In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV)...
- Plasmodium falciparum gametocyte carriage in asymptomatic children in western KenyaJ Teun Bousema
Department of Medical Microbiology, University Medical Centre, Nijmegen, The Netherlands
Malar J 3:18. 2004..This study identified factors that influence gametocytaemia in asymptomatic children in the absence and presence of pyrimethamine-sulphadoxine (SP) antimalarial treatment...
- HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virusE Michelle Long
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
AIDS Res Hum Retroviruses 18:567-76. 2002....
- Factors associated with self-reported unprotected anal sex among male sex workers in Mombasa, KenyaScott Geibel
Population Council, Nairobi, Kenya
Sex Transm Dis 35:746-52. 2008To identify social and behavioral characteristics associated with sexual risk behaviors among male sex workers who sell sex to men in Mombasa, Kenya.
- Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventionsTimothy O Abuya
Kenya Medical Research Institute Wellcome Trust Centre for Geographic Medicine Research Coast, Kilifi, Kenya
Malar J 6:57. 2007..Data on adult use of over-the-counter (OTC) medicines is limited. This study aimed to assess childhood and adult patterns of OTC medicine use to inform national medicine retailer programmes in Kenya and other similar settings.
- Laboratory epidemiologist: skilled partner in field epidemiology and disease surveillance in KenyaM Kariuki Njenga
Global Disease Detection Division, Centers for Disease Control and Prevention, Nairobi, Kenya
J Public Health Policy 29:149-64. 2008..To overcome this, Kenya added a laboratory management component in 2004, creating the first field epidemiology and laboratory training ..
- Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell traitThomas N Williams
Kenya Medical Research Institute Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, PO Box 230, Kilifi District Hospital, Kilifi, Kenya
Nat Genet 37:1253-7. 2005..We investigated this question by studying a population on the coast of Kenya and found that the protection afforded by each condition inherited alone was lost when the two conditions were ..
- Multiple virus lineages sharing recent common ancestry were associated with a Large Rift Valley fever outbreak among livestock in Kenya during 2006-2007Brian H Bird
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 14, Atlanta, GA 30329, USA
J Virol 82:11152-66. 2008..consistent with RVF virus infection emerged across semiarid regions of the Garissa District of northeastern Kenya and southern Somalia...
- Spatial distribution of anopheline larval habitats in Western Kenyan highlands: effects of land cover types and topographyNoboru Minakawa
Faculty of Medicine, Saga University, Saga, Japan
Am J Trop Med Hyg 73:157-65. 2005The distributions of anopheline larval habitats were aggregated in valley bottoms in Kenya in both the rainy and dry seasons, although the degree of aggregation was higher in the dry season than in the rainy season...
- Evidence for transmission of Plasmodium vivax among a duffy antigen negative population in Western KenyaJeffrey R Ryan
Walter Reed Army Institute of Research, Washington, DC, USA
Am J Trop Med Hyg 75:575-81. 2006..with characteristics of Plasmodium vivax is being transmitted among Duffy blood group-negative inhabitants of Kenya. Thirty-two of 4,901 Anopheles gambiae and An. funestus (0...
- Causes and outcome of young infant admissions to a Kenyan district hospitalM English
Centre for Geographic Medicine Research Coast, KEMRI Wellcome Trust Research Laboratories, PO Box 230, Kilifi, Kenya
Arch Dis Child 88:438-43. 2003To provide a comprehensive description of young infant admissions to a first referral level health facility in Kenya. These data, currently lacking, are important given present efforts to standardise their care through the integrated ..
- Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malariaFaith H A Osier
KEMRI Centre for Geographic Medicine Research, Coast, P O Box 230 80108, Kilifi, Kenya
Infect Immun 76:2240-8. 2008....
- Beginning community engagement at a busy biomedical research programme: experiences from the KEMRI CGMRC-Wellcome Trust Research Programme, Kilifi, KenyaVicki Marsh
KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
Soc Sci Med 67:721-33. 2008..A major component of the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Programme is centred on Kilifi District General ..
- Delivery of paediatric care at the first-referral level in KenyaMike English
KEMRI Centre for Geographic Medicine Research Coast, PO Box 230, Kilifi, Kenya
Lancet 364:1622-9. 2004We aimed to investigate provision of paediatric care in government district hospitals in Kenya. We surveyed 14 first-referral level hospitals from seven of Kenya's eight provinces and obtained data for workload, outcome of admission, ..
- HIV-1 infection in high risk men who have sex with men in Mombasa, KenyaEduard J Sanders
Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute KEMRI Kilifi, Kilifi, Kenya
AIDS 21:2513-20. 2007..We aimed to assess the risk factors for prevalent HIV-1 infection among men who have sex with men (MSM) to guide HIV-1 prevention efforts...
- Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, KenyaWendy P O'Meara
Kenya Medical Research Institute, Centre for Geographic Medicine Research Wellcome Trust Collaborative Program, Kilifi, Kenya Fogarty International Center, National Institutes of Health, Bethesda, MD, USA
Lancet 372:1555-62. 2008..We aimed to assess the epidemiological characteristics of malaria in Kilifi, Kenya, during a period of decreasing transmission intensity.
- Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variantsP C Bull
Kenya Medical Research Institute CGMRC, Kilifi Unit, Kilifi, Kenya
Infect Immun 67:733-9. 1999..In a study in Kenya, 21 parasite isolates, including nine from children with severe malaria, were tested for agglutination by 33 pairs ..
- Body dimensions, exercise capacity and physical activity level of adolescent Nandi boys in western KenyaH B Larsen
The Copenhagen Muscle Research Centre, Rigshospitalet and University of Copenhagen, Denmark
Ann Hum Biol 31:159-73. 2004..6 years) from a town (n = 11) and from a rural area (n = 19) in western Kenya (altitude approximately 2000 m.a.s.l...
- Policy implications of the inadequate support systems for orphans in western KenyaE O Nyambedha
Institute of African Studies, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
Health Policy 58:83-96. 2001..systems available for orphans in a rural Luo community in Nyang'oma sub-location in Bondo District of Western Kenya. Qualitative data were collected through in-depth interviews with orphaned children and their caretakers as well ..
- A prospective study assessing the effects of introducing the female condom in a sex worker population in Mombasa, KenyaS C Thomsen
Family Health International, Institute for Family Health, NC 27709, USA
Sex Transm Infect 82:397-402. 2006To assess the impact and costs of adding female condoms to a male condom promotion and distribution peer education programme for sex workers in Mombasa, Kenya.
- Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in KenyaIndu Malhotra
Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio, USA
PLoS Med 6:e1000116. 2009..We hypothesized that fetal immune priming, or malaria exposure in the absence of priming (putative tolerance), affects the child's susceptibility to subsequent malaria infections...
- Polymorphism of Fc receptor IIa for immunoglobulin G is associated with placental malaria in HIV-1-positive women in western KenyaKimberly C Brouwer
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee, GA 30341, USA
J Infect Dis 190:1192-8. 2004..The present study was undertaken to examine the relationship between Fc gamma RIIa polymorphism and placental malaria (PM) in pregnant women of known human immunodeficiency virus (HIV)-1 status...
- Health problems of street children in Eldoret, KenyaS O Ayaya
Department of Child Health and Paediatrics, Faculty of Health Sciences, Moi University, Eldoret, Kenya
East Afr Med J 78:624-9. 2001..DESIGN: A prospective and descriptive study. SETTING: Eldoret Town, Kenya. SUBJECTS: Eldoret street children aged 5-21 years...
- Atopy, asthma, and antibodies to Ascaris among rural and urban children in KenyaMatthew S Perzanowski
University of Virginia Asthma and Allergic Diseases Center, Health Sciences Center, Charlottesville, 22908 1355, USA
J Pediatr 140:582-8. 2002The purpose of this study was to evaluate differences in the relationship between asthma and immune responses to allergens in children living in rural and urban areas of Kenya.
- Trends and determinants of contraceptive method choice in KenyaMonica A Magadi
African Population and Health Research Center, Nairobi, Kenya
Stud Fam Plann 34:149-59. 2003This study uses data from the 1989, 1993, and 1998 Kenya Demographic and Health Surveys to examine trends and determinants of contraceptive method choice in Kenya...
- Oviposition behavior of female Anopheles gambiae in western Kenya inferred from microsatellite markersHong Chen
Program in Public Health, College of Health Sciences, University of California, Irvine, 92697, USA
Am J Trop Med Hyg 75:246-50. 2006..isolated hut and all larvae from larval habitats within 100 m of the hut were collected in August 2001 in western Kenya. Among 42 aquatic habitats, 16 had A. gambiae larvae...
- Sampling-based approaches to improve estimation of mortality among patient dropouts: experience from a large PEPFAR-funded program in Western KenyaConstantin T Yiannoutsos
Indiana University Division of Biostatistics, Indianapolis, IN, USA
PLoS ONE 3:e3843. 2008..Sampling-based approaches and statistical adjustment are the only scaleable methods permitting accurate estimation of M&E indices...
- The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, KenyaOsman Abdullahi
Wellcome Trust Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
Pediatr Infect Dis J 27:59-64. 2008..In East Africa we do not know how these pathogens are transmitted between population subgroups nor which serotypes circulate commonly...
- Attitudes toward psychiatry: a survey of medical students at the University of Nairobi, KenyaDavid M Ndetei
Department of Psychiatry, University of Nairobi, Kenya
Acad Psychiatry 32:154-9. 2008The authors aim to determine the attitudes of University of Nairobi, Kenya, medical students toward psychiatry.
- Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western KenyaPatrick O Monahan
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 3002, USA
J Gen Intern Med 24:189-97. 2009..Patient Health Questionnaire-9 (PHQ-9), a brief dual-purpose instrument yielding DSM-IV diagnoses and severity, and PHQ-2, an ultra-brief screening tool, offer advantages in resource-constrained settings...
- Safeguarding maternal and newborn health: improving the quality of postnatal care in KenyaCharlotte Warren
Population Council, General Accident Insurance House, Ralph Bunche Road, PO Box 17643, Nairobi 00500, Kenya
Int J Qual Health Care 22:24-30. 2010..To assess changes in the quality of care following the introduction of a new postnatal package...
- Adult male circumcision does not reduce the risk of incident Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis infection: results from a randomized, controlled trial in KenyaSupriya D Mehta
Department of Epidemiology, University of Illinois at Chicago School of Public Health, Chicago, Illinois, USA
J Infect Dis 200:370-8. 2009..We examined the effect of male circumcision on the acquisition of 3 nonulcerative sexually transmitted infections (STIs)...
- Community health worker performance in the management of multiple childhood illnesses: Siaya District, Kenya, 1997-2001J M Kelly
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341 3724, USA
Am J Public Health 91:1617-24. 2001To characterize community health worker (CHW) performance using an algorithm for managing common childhood illnesses in Siaya District, Kenya, we conducted CHW evaluations in 1998, 1999, and 2001.
- Aflatoxin contamination of commercial maize products during an outbreak of acute aflatoxicosis in eastern and central KenyaLauren Lewis
National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, Georgia 30341, USA
Environ Health Perspect 113:1763-7. 2005In April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths...
- What is youth-friendly? Adolescents' preferences for reproductive health services in Kenya and ZimbabweAnnabel S Erulkar
Population Council, Accra, Ghana
Afr J Reprod Health 9:51-8. 2005..Large scale population-based surveys were carried out among youth in Kenya and Zimbabwe...
- Factors sustaining pediatric adherence to antiretroviral therapy in western KenyaRachel C Vreeman
Indiana University School of Medicine, Department of Pediatrics, Children s Health Services Research, Indianapolis, Indiana 46202, USA
Qual Health Res 19:1716-29. 2009..individual interviews were conducted with parents and guardians of HIV-infected children receiving ART in western Kenya. Interviews covered multiple aspects of the experience of having children take ART and factors that inhibited or ..
- Rapid assessment of avoidable blindness in Nakuru district, KenyaWanjiku Mathenge
Rift Valley Provincial Hospital, Nakuru, Kenya
Ophthalmology 114:599-605. 2007To estimate the prevalence of avoidable blindness in > or =50-year-olds in Nakuru district, Kenya, and to evaluate the Rapid Assessment for Avoidable Blindness (RAAB), a new methodology to measure the magnitude and causes of blindness.
- Heavy metals in mosquito larval habitats in urban Kisumu and Malindi, Kenya, and their impactPaul O Mireji
Department of Biochemistry, Kenyatta University, P O Box 43844, Nairobi 00100, Kenya
Ecotoxicol Environ Saf 70:147-53. 2008..cadmium, chromium, copper, iron, lead, manganese and zinc in mosquito larval habitats in urban Kisumu and Malindi, Kenya and their effect on the presence of Anopheles gambiae, Aedes aegypti, Culex quinquefasciatus and Anopheles ..
- High prevalence of asymptomatic plasmodium falciparum infections in a highland area of western Kenya: a cohort studyFrederick N Baliraine
Program in Public Health, College of Health Sciences, University of California at Irvine, Irvine, California 92697, USA
J Infect Dis 200:66-74. 2009Transmission of malaria in an area of hypoendemicity in the highlands of western Kenya is not expected to lead to rapid acquisition of immunity to malaria...
- Topography and malaria transmission heterogeneity in western Kenya highlands: prospects for focal vector controlAndrew K Githeko
Climate and Human Health Research Unit, Centre for Vector Biology and Control Research, Kenya Medical Research Institute, Kisumu, Kenya
Malar J 5:107. 2006Recent resurgence of malaria in the highlands of Western Kenya has called for a more comprehensive understanding of the previously neglected complex highland vector ecology...
- Performance of malaria rapid diagnostic tests as part of routine malaria case management in KenyaAlexandre Macedo de Oliveira
Malaria Branch, Division of Parasitic Diseases, National Center for Vector Borne, Zoonotic, and Enteric Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Am J Trop Med Hyg 80:470-4. 2009..and health facility (HF) staffs as part of routine malaria case management of patients > or = 5 years of age in Kenya. Expert microscopy was used as our gold standard. A total of 1,827 patients were enrolled; 191 (11...
- High mortality in a cholera outbreak in western Kenya after post-election violence in 2008O Tipo Shikanga
Field Epidemiology and Laboratory Training Program Kenya, Centers for Disease Control and Prevention, Nairobi, Kenya
Am J Trop Med Hyg 81:1085-90. 2009In 2008, a cholera outbreak with unusually high mortality occurred in western Kenya during civil unrest after disputed presidential elections...
- Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen 1 and thrombospondin-related adhesive protein immunodominant epitopes in a highland population from Western KenyaAnn M Moormann
Center for Global Health and Diseases, and Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio, 44106 7286, USA
Am J Trop Med Hyg 81:489-95. 2009..thrombospondin-related adhesive protein (TRAP) were evaluated over a nine-month interval in adults and children in Kenya from a malaria epidemic-prone highland area after several years of low transmission...
- Interepidemic Rift Valley fever virus seropositivity, northeastern KenyaA Desiree LaBeaud
Rainbow Babies and Children s Hospital, Cleveland, Ohio, USA
Emerg Infect Dis 14:1240-6. 2008..In a randomized household cluster survey in 2 areas of Ijara District, Kenya, we examined 248 residents of 2 sublocations, Gumarey (village) and Sogan-Godud (town)...
- New records of Anopheles arabiensis breeding on the Mount Kenya highlands indicate indigenous malaria transmissionHong Chen
Program in Public Health, College of Health Sciences, University of California, Irvine, CA 92697, USA
Malar J 5:17. 2006Malaria cases on the highlands west of Mount Kenya have been noticed since 10-20 years ago...
- Deforestation and vectorial capacity of Anopheles gambiae Giles mosquitoes in malaria transmission, KenyaYaw A Afrane
Kenya Medical Research Institute, Kisumu, Kenya
Emerg Infect Dis 14:1533-8. 2008..We showed that deforestation changes microclimates, leading to more rapid sporogonic development of P. falciparum and to a marked increase of malaria risk in the western Kenyan highland...
- The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya I. Development of infrastructure and description of study sitePenelope A Phillips-Howard
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Am J Trop Med Hyg 68:3-9. 2003..group-randomized, controlled trial in an area of high and year-round malaria transmission in western Kenya. We outline the development of the human and physical infrastructure required to conduct this trial and discuss ..
- High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya)Hirotomo Kato
Vector Molecular Biology Unit, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
BMC Genomics 7:226. 2006..Salivary gland cDNA libraries were prepared from wild-caught P. duboscqi from Mali and recently colonised flies of the same species from Kenya.
- The role and performance of chest X-ray for the diagnosis of tuberculosis: a cost-effectiveness analysis in Nairobi, KenyaM R A van Cleeff
KNCV Tuberculosis Foundation, The Hague, The Netherlands
BMC Infect Dis 5:111. 2005....
- Longitudinal study of natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in a holoendemic region of malaria in western Kenya: Asembo Bay Cohort Project VIIIV Udhayakumar
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia, USA
Am J Trop Med Hyg 65:100-7. 2001..and antibody responses to apical membrane antigen-1 (AMA-1) epitopes in a holoendemic area of western Kenya. Young children (< 10 years), older children (10-17 years), and adults (> or = 18 years) were followed ..
- Possible interruption of malaria transmission, highland Kenya, 2007-2008Chandy C John
Global Pediatrics Program, University of Minnesota Medical School, 420 Delaware St SE, 850 Mayo, MMC 296, Minneapolis, MN 55455, USA
Emerg Infect Dis 15:1917-24. 2009..In highland areas of Kipsamoite and Kapsisiywa, Kenya (population approximately 7,400 persons), annual household indoor residual spraying with a synthetic pyrethroid ..
- Changing patterns of clinical malaria since 1965 among a tea estate population located in the Kenyan highlandsG D Shanks
US Army Medical Research Unit Kenya
Trans R Soc Trop Med Hyg 94:253-5. 2000..malaria since 1965 among hospitalized patients was studied at a group of tea estates in the western highlands of Kenya. These data indicate recent dramatic increases in the numbers of malaria admissions (6.5 to 32...
- Association of HIV infection with distribution and viral load of HPV types in Kenya: a survey with 820 female sex workersStanley M F Luchters
International Centre for Reproductive Health ICRH, Ghent University, Belgium
BMC Infect Dis 10:18. 2010..Interactions between these infections pose substantial public health challenges, especially where HIV prevalence is high and HPV vaccine coverage low...
- Improving TB Diagnosis in Children with and without HIV in KenyaRinn Song; Fiscal Year: 2013..I have developed a comprehensive career development plan which will allow me to implement two research studies in Kenya, and complete a Master of Public Health degree and pursue additional educational training in advanced ..
- Impacts of surface receptors [Toll like receptor (TLRs) and Fc gamma receptors (FCollins Ouma; Fiscal Year: 2012..falciparum transmission areas, such as western Kenya. The overall objective of this proposal, therefore, is to investigate the functional impact of variation within ..
- Parenting, Adolescent Self-Regulation, and Risk-Taking Across CulturesJennifer E Lansford; Fiscal Year: 2013..and their mothers and fathers from 13 cultures (Jinan and Shanghai, China;Colombia;Naples and Rome, Italy;Jordan;Kenya;Philippines;Sweden;Thailand;and African, European, and Hispanic Americans in the United States)...
- Evo-epidemiology of Scistosoma mansoni in children in KenyaERIC SAMUEL LOKER; Fiscal Year: 2010DESCRIPTION (provided by applicant): This research will be done primarily in Kenya at the Kenya Medical Research Institute (KEMRI) in Mwea and Nairobi, in collaboration with Dr...
- Role of Protective and Pathogenic B cells in Modulating Pediatric Severe MalariaTom Were; Fiscal Year: 2013..falciparum transmission area of western Kenya. The overall hypothesis of this proposal is that PfHz alters the production of cytokines (IL-10, TNF-α, ..
- Tsetse Transmitted African TrypanosomiasisSerap Aksoy; Fiscal Year: 2013..In this renewal application Yale University scientists will continue to work with the Kenya Trypanosomiasis Research Center (TRC), World Health Organization designated Center of Excellence, to coordinate ..
- Innate Immune Sensing of Rift Valley Fever VirusAmy G Hise; Fiscal Year: 2010..Based on recent work in Kenya, we have determined that the extent of RVFV transmission to humans is much greater than previously suspected, both ..
- Training in Sexually Transmitted Diseases Including HIVStanley M Spinola; Fiscal Year: 2013..The implementation research tract focuses on HIV- 1 care in western Kenya. Candidates must be MDs or PhDs with interest in STD or HIV-1 research...
- Transcriptomics and Population Genetics of Mosquito Resistance to PyrethroidsMariangela Bonizzoni; Fiscal Year: 2013..gambiae mosquitoes from Kenya. This project will significantly enhance the knowledge of the molecular mechanism of insecticide resistance in An...
- Vertical CMV transmission in the setting of maternal HIV-1 infection in KenyaJENNIFER ANN SLYKER; Fiscal Year: 2013..The research findings will be central to the design of interventions to interrupt vertical cytomegalovirus transmission, a strategy aimed at reducing morbidity and mortality in HIV- infected infants. ..
- Computerized Counseling to Promote Positive Prevention and HIV Health in KenyaAnn Elizabeth Kurth; Fiscal Year: 2012..in reducing HIV-1 viral load and risk behaviors in the US ('CARE+') with the largest HIV provider in Kenya, the Academic Model for the Prevention and Treatment of HIV/AIDS (AMPATH)...
- Demography of Sex Differences in Health and SurvivalJames W Vaupel; Fiscal Year: 2013..3) and in Japan, the Philippines and Singapore (Project 4); Longitudinal observations on baboons in the wild in Kenya (Project 5); Longitudinal data on lemurs in the wild on Madagascar and in captivity at Duke and in France (Project ..
- Determinants of resistance in human schistosomiasisDaniel G Colley; Fiscal Year: 2013..The research will be done with cohorts in and near Kisumu, Kenya, where there is year-round transmission of S...
- Institutional Collaboration between LSTM and CDC and Prevention on Malaria(U01)FEIKO OLAF TER KUILE; Fiscal Year: 2013..between LSTM, CDC and the overseas partners of CDC in Indonesia (the Eijkman Institute, Jakarta) and in western Kenya (KEMRI-CDC field station)...
- Human neutralizing monoclonal antibodies for Rift Valley fever virusJames E Crowe; Fiscal Year: 2013..The virus is most common in the Rift Valley of East Africa, especially Kenya, Somalia and Tanzania, but also has now spread outside the African continent to Saudi Arabia and Yemen...
- Parent Behavior and Child Adjustment Across CulturesJennifer E Lansford; Fiscal Year: 2010..e., China, India, Italy, Kenya, Philippines, Sweden, Thailand, United States) and subgroups within these countries...
- Optimizing Maternal-Child Health in KenyaASOK ANTONY; Fiscal Year: 2013..There is a novel infrastructure in Eldoret, Kenya, at AMPATH (Academic Model Providing Access To Healthcare;http://www.iukenya...
- Ecology of African Highland MalariaGuiyun Yan; Fiscal Year: 2012..hypothesis using epidemiological, entomological, and molecular population genetics data in western Kenya highlands...
- Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)Sten H Vermund; Fiscal Year: 2013..together in the US and LMIC partner institutions, selected as diverse, well-funded research sites in Africa (Kenya, Zambia, Tanzania, Rwanda), Asia (India, China, Vietnam), Latin America (Brazil, Mexico), and the Caribbean (Haiti)..
- Global Network for Women's and Children's HealthEdward A Liechty; Fiscal Year: 2012..We propose to develop a Global Network for Women's and Children's Health Research site in Eldoret, Kenya. This East African site will be a joint partnership between Indiana University and Moi University School of ..
- HIV Testing and Educating Male Partners to Improve Maternal and Infant OutcomesCarey Farquhar; Fiscal Year: 2013..Ministry of Health's National AIDS and STD Control Program (NASCOP), the University of Nairobi, and the Kenya Medical Research Institute to incorporate male partners into antenatal care by providing home-based partner ..
- H3Africa Kidney Disease Research NetworkAkinlolu O Ojo; Fiscal Year: 2013..362 million (Ethiopia, Ghana, Kenya, Nigeria and South Africa) and four North American institutions...
- Agricultural Intervention to Improve Health of HIV-infected and Affected ChildrenLisa Michelle Butler; Fiscal Year: 2013..is to determine the impact of an agricultural intervention targeting HIV-affected households in Nyanza Province, Kenya, on important health measures for children under five years old, including nutritional status, disease incidence, ..
- Effect of Lactobacillus on genital HIV-1 RNA and DNA shedding in womenJane E Hitti; Fiscal Year: 2010..lavage (CVL) and cervical cytobrush samples from parallel cohorts of HIV-1-infected women in the United States and Kenya. Specifically, we will: 1. Examine the effect over time of L. crispatus, L. jensenii and L...
- TRAINING IN GEOGRAPHIC MEDICINE AND INFECTIOUS DISEASESJAMES WALTER KAZURA; Fiscal Year: 2013..g. Uganda, Kenya, Papua New Guinea, Brazil and South Africa. U.S...
- Development of a forced air add-on attachment for rocket stoves in Kenya capableNATHAN LORENZ; Fiscal Year: 2013..5 particulates in rural homes of developing countries such as Kenya has been observed to exceed World Health Organization (WHO) exposure limits up to 30X, and US Environmental ..
- Optimizing Linkage and Retention to Hypertension Care in Rural KenyaValentin Fuster; Fiscal Year: 2013DESCRIPTION (provided by applicant): Optimizing Linkage and Retention to Hypertension Care in Rural Kenya. Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults above age 30...
- Cancer and tobacco control training and research across the lifespan in KenyaScot C Remick; Fiscal Year: 2013..by applicant): The burden of cancer and tobacco consumption are major causes of morbidity and mortality in Kenya, a country with limited research infrastructure and significant scarcity to address these ever increasing chronic, ..
- Plasmodium Genus and P. falciparum - P. vivax FISH AssaysJyotsna Shah; Fiscal Year: 2009..Specific Aims for Phase III (1) Filing 510K or PMA. (2)Set up manufacturing in Kenya. (3): Marketing. (4) Work with WHO to obtain their stamp of approval...
- East Africa IEDEA Regional ConsortiumCONSTANTIN THEODORE YIANNOUTSOS; Fiscal Year: 2013DESCRIPTION (provided by applicant): The three countries within the East African leDEA Regional Consortium (Kenya, Uganda, Tanzania) have adult HIV prevalence rates ranging between 5-10%...
- Clinical Epidemiology and Pathogenesis of Asymptomatic HSVAnna Wald; Fiscal Year: 2013..We will establish a cohort of HSV-2/HIV negative adolescent women in Thika, Kenya. The women who acquire HSV-2 infection will be enrolled into a 60-day intensive study of HSV-2 shedding, during ..
- Increasing Animal Foods in Diets of HIV-Infected Kenyan Women and Their ChildrenJudith A Ernst; Fiscal Year: 2011..drug nave HIV-infected women and their HIV negative (affected) children and their HIV-infected children in rural Kenya, provided a meat derived supplement, have improved nutritional and clinical outcomes, growth and development in ..
- Nurse Management of Hypertension in Rural Western KenyaRajesh Vedanthan; Fiscal Year: 2013Project Summary: Nurse Management of Hypertension in Rural Western Kenya Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults above age 30...
- Latent TB Detection and Implications in HIV-1 Infected Women and Their ChildrenGrace C John Stewart; Fiscal Year: 2010..We propose to use a historical cohort of >400 HIV-1 infected mothers and their children from Nairobi, Kenya to determine the prevalence and correlates of LTBI detection using IGRAs...
- Identifying community-based solutions that improve insecticide-treated net (ITN)Kacey C Ernst; Fiscal Year: 2012..Our preliminary results indicate that in Kenya roughly 1 in 4 children under 5, the group most vulnerable to malaria, live in households that do not own a bednet...
- HIV/AIDS and Orphan CareKathryn Whetten; Fiscal Year: 2013..randomly selected OAC in six culturally diverse study sites in Cambodia, Ethiopia, India (Nagaland and Hyderabad), Kenya, and Tanzania...
- HIV-1 and Protective Immunity against Common Childhood PathogensCarey Farquhar; Fiscal Year: 2013..fellows and students pursuing a career in patient-oriented research at the University of Washington (UW) and in Kenya. Dr...
- Relationship between vaginal micobiota and T. vaginalis acquisitionOLAMIDE DAPHNA JARRETT; Fiscal Year: 2013..The proposed educational plan includes work in Kenya, advanced studies in HIV/STI research at UW and UIC, as well as advanced studies in epidemiology and health policy ..
- MALE CIRCUMCISION FOR HIV PREVENTION IN KENYA: EFFECTIVE STRATEGIES TO RECRUIT OLKawango Agot; Fiscal Year: 2013Title: Male Circumcision for HIV Prevention in Kenya: Seeking effective strategies to recruit older men Background: In Kenya, 1.4-1.6 million people are living with HIV, with an adult prevalence of 6.3%...
- Molecular and functional characterization of olfaction genes in tsetse fliesSerap Aksoy; Fiscal Year: 2013..Glossina pallidipes, Glossina austeni and Glossina fuscipes fuscipes) of medical and veterinary importance in Kenya. We propose an integrated and interdisciplinary approach to: 1) Determine differences in olfactory responsive ..
- The effect of the penile microbiome on BV, GUD, and genital epithelial traumaSUPRIYA DINESH MEHTA; Fiscal Year: 2013..In both our MMC trial in Kenya and the Ugandan MMC trial, circumcised men had lower prevalence and amount of penile anaerobic bacteria, several ..
- Reproductive health decisions and HIV infection riskAnn Elizabeth Kurth; Fiscal Year: 2012..and sexual health data, and pregnancy and HIV incidence from men and women in Nyando district, western Kenya. A randomly-selected cohort of HIV discordant (n?960), concordant-negative (subset of n?960) and concordant-..
- Sustainable Financial Incentives To Improve Prescription Practices For MalariaWENDY PRUDHOMME O'MEARA; Fiscal Year: 2013..In a typical rural health facility in Kenya, more tan 90% of febrile patients are prescribed an antimalarial when no diagnostic tests are available...
- AIDS INTERNATIONAL TRAINING AND RESEARCH PROGRAMCarey Farquhar; Fiscal Year: 2012..During the last 15 years, training efforts have focused on 4 target countries, Kenya, Peru, Mozambique, and Thailand, and 96% of trainees from these countries have returned to their home countries ..
- Evidence based control strategies of Sleeping Sickness vectorsSerap Aksoy; Fiscal Year: 2012..the head of tsetse genomic research and Deputy Director of the national Trypanosomiasis Research Center (TRC) in Kenya. Kenya is at risk of HAT outbreaks due to ongoing epidemics in neighboring Uganda and increased movement of people ..
- Causes of early mortality in HIV-infected Africans on antiretroviral therapyABRAHAM MOSIGISI SIIKA; Fiscal Year: 2012..Partnership (AMPATH) has enrolled >80,000 HIV-infected patients across 18 urban and rural care sites in western Kenya, >40,000 of whom have initiated ART. To date, 5,500 patients have been confirmed dead, half of whom were on ART...
- Targeted Treatment of Early Cryptococcal Infection in HIV-infected PatientsANA CLAIRE LEW MEYER; Fiscal Year: 2012..Phase IIb randomized controlled clinical trial based at Family AIDS Care and Education Services (FACES) in Western Kenya, we will determine the safety and estimate the efficacy of combination therapy with oral flucytosine and ..
- Nutrition and HIV ProgressionChristine A Wanke; Fiscal Year: 2013..Specifically we propose to enroll 740 HIV infected women in Kenya, with CD4 counts between 350 cells/<L and 500 cells/<Land no symptoms, opportunistic infections or AIDS ..
- Poverty, Stress, and Discounting: A potential micro-mechanism for behavior changeJohannes Haushofer; Fiscal Year: 2013..We take advantage of a unique natural experiment among the Maasai of Southern Kenya: using rainfall data as an instrumental variable, we can identify the causal effect of an exogenous increase in ..
- Evaluation of antiretroviral HIV prevention in African HIV discordant couplesJared Baeten; Fiscal Year: 2012..conducting a placebo-controlled clinical trial of tenofovir-based PrEP among 4700 HIV-1 serodiscordant couples in Kenya and Uganda (the Partners PrEP Study), which will be completed in 2012...
- The Burden of Chikungunya and Dengue Transmission, Infection and Disease in KenyaAngelle Desiree LaBeaud; Fiscal Year: 2013..Our objectives are to assess the true burden of human disease related to DENV strains 1-4 and for CHIKV across Kenya, and then to determine the drivers of viral circulation, estimate the thresholds for outbreak initiation, and ..
- Low-Cost Catalytic Biomass Cookstove for Improved Indoor Air QualityPAUL YELVINGTON; Fiscal Year: 2013..strategy for the advanced cook stove seeks to manufacture the stoves in developing countries like Kenya, where the stoves would be sold. This approach will lower manufacturing costs and provide local jobs...
- Naturally Acquired Immunity to Malaria during the Epidemiologic Transition in KenJAMES WALTER KAZURA; Fiscal Year: 2013..Our previous research in western Kenya has been concerned with elucidating the mechanisms underlying age-related naturally acquired immunity, with a ..
- HIV/STI outcomes from male circumcision in men and female partners: Kisumu, KenyaSUPRIYA DINESH MEHTA; Fiscal Year: 2010..In our RCT, MMC more than halved the risk of HIV seroconversion [RR = 0.41] among men aged 18-24 years in Kisumu, Kenya. Despite this, the 2-year HIV seroconversion rate was 2.1% for circumcised men...
- Trial of Male Circumcision to Reduce HIV IncidenceRobert Bailey; Fiscal Year: 2009..This application seeks support for continuation of a randomized controlled trial of male circumcision in Kisumu, Kenya. The main objective is to assess the effectiveness of MC in reducing HIV incidence in young, sexually active men...
- Northern/Pacific Universities Global Health Research Training ConsortiumJOSEPH RAYMOND ZUNT; Fiscal Year: 2013..Michigan, Minnesota and Washington) and partnerships with universities and research institutions in six countries (Kenya, Ghana, Uganda, Peru, China and Thailand)...
- STERILITY IN SUB-SAHARAN AFRICAUlla Larsen; Fiscal Year: 1992..The countries to be studies are the following: Benin, Botswana, Burundi, Cameroon, Ghana, Ivory Coast, Kenya, Lesotho, Liberia, Mali, Mauritania, Nigeria, Senegal, Sudan, Togo, Uganda, and Zimbabwe...
- Understanding the biology of schistosomes in response to praziquantelCharles Cunningham; Fiscal Year: 2010..mansoni. A genetically diverse population of S. mansoni derived from natural infections in Kenya will be selected in mice for their varied sensitivities to PZQ...
- TRAINING AND RESEARCH ON SEVERE MALARIAL ANEMIADOUGLAS JAY PERKINS; Fiscal Year: 2013..In addition, we will expand our training platform to meet the growing demands of the scientific community in Kenya and internationally. The expanded program will include training in drug and vaccine discovery and biostatistics...
- MULTIDISCIPLINARY ENVIRONMENTAL HEALTH TRAININGDavid Carpenter; Fiscal Year: 2006..training program in environmental health in the following countries; Romania, Russia, Uzbekistan, Mongolia, Kenya and Uganda...
- Improving Health Outcomes for Orphans by Preventing HIV/STD Risk.Kathryn Whetten; Fiscal Year: 2013..and young adolescents in two East African sites with high prevalence HIV, Moshi, Tanzania (TZ) and Bungoma, Kenya (KE), through a randomized controlled trial (RCT)...
- Promoting Engagement in HIV Services among Adolescents in KenyaWINFRED K LUSENO; Fiscal Year: 2013..because there are no systems that track linkage to care among those who test positive and are referred to care in Kenya. Research, however, suggests that younger infected individuals are less likely to be enrolled in care than older ..
- 2/2 - Establishing a GEOHealth Hub Platform for East Africa - EthiopiaABERA TAKELE KUMIE; Fiscal Year: 2013..Center and Network (HOAREC/N), a partner in this application (which includes one of our targeted countries - Kenya), and to Uganda and Rwanda through USC collaborations...
- Randomized Trial/Reduce Recurrence/Bacterial VaginosisKing Holmes; Fiscal Year: 2004..Women in sub-Saharan Africa have the highest prevalence of BV, approximately 40-50 percent in Uganda and Kenya. Thus with such a high prevalence and approximately a 2-fold increased risk of HIV acquisition in women with BV, ..
- Building a Joint International IRB for Moi University and Indiana UniversityERIC MARK MESLIN; Fiscal Year: 2010..operate a new Ethics Review Committee between Indiana University and Moi University School of Medicine in Eldoret, Kenya This new international IRB will be responsible for reviewing and approving proposals undertaken jointly by these ..
- Molecular tools to monitor eradication of Schistosoma haematobium transmissionCharles King; Fiscal Year: 2009..haematobium-endemic areas in Kenya. 4...
- DIARRHEAL DISEASE STUDYRoger Shapiro; Fiscal Year: 2004..projects focused on international health issues; he established a diarrheal surveillance system in rural western Kenya, and performed case-control and cohort studies in Kenya and Argentina...
- Liberia School-Based HIV/STD Prevention ProgramStephen Kennedy; Fiscal Year: 2009..1998) that is currently being adapted in other Sub-Saharan African countries (e.g., Ghana, Kenya, South Africa, Swaziland, Liberia, etc.)...
- Oral Chemotherapy in AIDS-related NHL in Uganda & KenyaScot Remick; Fiscal Year: 2003..This proposal would support the first clinical trial in AIDS-related NHL in Uganda and Kenya with important laboratory correlative studies on: 1) underlying HIV infection including monitoring of CD4 ..
- Dynamic Ecological Simulation Model of Tsetse Transmitted Trypanosomosis in KenyaJoseph P Messina; Fiscal Year: 2010..disturbance on the ecological distribution of tsetse flies and African Trypanosomiasis or sleeping sickness across Kenya. This study responds to the announcement by specifically employing an interdisciplinary team to develop and deploy ..
- Electronic Medical Records to Improve Patient Care & Public Health in Rural KenyaWilliam Tierney; Fiscal Year: 2009..Developers from Indiana University, the Regenstrief Institute, and their collaborators at Moi University in Kenya created sub-Saharan Africa's first ambulatory electronic medical record system that served (and still serves) ..
- An Ecological Analysis of Cryptosporidium in KenyaJeffrey Griffiths; Fiscal Year: 2004DESCRIPTION (Provided by the applicant): This research will be done in Kenya as an extension of NIH grant 1 R01 AI 43415-01A1...