Genomes and Genes
africa south of the sahara
Summary: All of Africa except Northern Africa (AFRICA, NORTHERN).
Publications260 found, 100 shown here
- Hepatitis B virus and human immunodeficiency virus co-infection in sub-Saharan Africa: a call for further investigationR J Burnett
The HIV AIDS and Viral Hepatitis Research Laboratory, Department of Virology, University of Limpopo Medunsa Campus, PO Box 173, Medunsa 0204, South Africa
Liver Int 25:201-13. 2005..This paper reviews studies that have investigated HIV and HBV co-infection in sub-Saharan Africa, against a backdrop of what is currently known about the interactions between these two viruses...
- A climate-based distribution model of malaria transmission in sub-Saharan AfricaM H Craig
National Malaria Research Programme, South African Medical Research Council, PO Box 17120, Congella, Durban 4013, South Africa
Parasitol Today 15:105-11. 1999..Together with population, morbidity and mortality data, the model provides a fundamental tool for strategic control of malaria...
- The epidemiology and burden of Plasmodium falciparum-related anemia among pregnant women in sub-Saharan AfricaH L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Nairobi
Am J Trop Med Hyg 64:36-44. 2001..2%. Assuming that 26% of these cases are due to malaria, it is suggested that as many as 400,000 pregnant women may have developed severe anemia as a result of infection with malaria in sub-Saharan Africa in 1995...
- The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan AfricaFeiko O Ter Kuile
Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
Am J Trop Med Hyg 71:41-54. 2004..There is a clear need to strengthen the deployment of existing malaria and HIV prevention and intervention measures for pregnant women...
- Malaria in pregnancy as an indirect cause of infant mortality in sub-Saharan AfricaH L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
Trans R Soc Trop Med Hyg 95:569-76. 2001..This may explain the high reduction in infant mortality rates from interventions aimed at reducing transmission, over and above that expected from a decline in direct malaria-specific mortality alone...
- Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapySamuel Shillcutt
Andean Health and Development Saludesa, Quito, Ecuador
Bull World Health Organ 86:101-10. 2008..To evaluate the relative cost-effectiveness in different sub-Saharan African settings of presumptive treatment, field-standard microscopy and rapid diagnostic tests (RDTs) to diagnose malaria...
- Antenatal syphilis in sub-Saharan Africa: missed opportunities for mortality reductionS Gloyd
Department of Health Services, Box 357660, University of Washington School of Public Health and Community Medicine, Seattle, WA 98195, USA
Health Policy Plan 16:29-34. 2001..DISCUSSION: Syphilis testing and treatment is a cost-effective intervention that deserves much greater attention, particularly in sub-Saharan Africa and other countries where syphilis infection is high...
- Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysisEdward J Mills
Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
JAMA 296:679-90. 2006..Concerns about incomplete adherence among patients living in poverty have been an important consideration in expanding the access to antiretroviral therapy in sub-Saharan Africa...
- Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatmentElizabeth L Corbett
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Lancet 367:926-37. 2006..Here, we review tuberculosis epidemiology in Africa and policy implications of HIV/AIDS treatment scale-up...
- Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malariaPeter J Hotez
Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, District of Columbia, USA
PLoS Med 3:e102. 2006
- Quantification of clinical morbidity associated with schistosome infection in sub-Saharan AfricaMarieke J van der Werf
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
Acta Trop 86:125-39. 2003..mansoni) at 150000 and 130000 per year. Given the overall high number of cases with schistosomiasis-related disease and associated death, we conclude that schistosomiasis remains an important public health problem in sub-Saharan Africa...
- Micronutrient supplements for children after dewormingAndrew Hall
Centre for Public Health Nutrition, School of Integrated Health, University of Westminster, London, UK
Lancet Infect Dis 7:297-302. 2007....
- Sustainable schistosomiasis control--the way forwardJurg Utzinger
Office of Population Research, Princeton University, NJ, Princeton 08544, USA
Lancet 362:1932-4. 2003
- HIV and cancer of the cervixZ M Chirenje
Department of Obstetrics and Gynaecology, College of Health Sciences, University of Zimbabwe, P O Box A178, Avondale, Harare, Zimbabwe
Best Pract Res Clin Obstet Gynaecol 19:269-76. 2005..The role of screening and the impact of antiretroviral treatment on the progression of pre-invasive and invasive cancer will also be discussed...
- Diabetes care in sub-Saharan AfricaDavid Beran
International Insulin Foundation, International Health and Medical Education Centre, University College London, London N19 5LW, UK
Lancet 368:1689-95. 2006..We review the current evidence on diabetes care in sub-Saharan Africa and propose an 11-point action plan to address this problem in the region...
- Malaria transmission in urban sub-Saharan AfricaVincent Robert
Institut de Recherche pour le Developpement, France
Am J Trop Med Hyg 68:169-76. 2003..Malaria control in urban environments may be simpler as a result of urbanization; however, much of what we know about malaria transmission in rural environments might not hold in the urban context...
- The epidemiology of HSV-2 infection and its association with HIV infection in four urban African populationsH A Weiss
London School of Hygiene and Tropical Medicine, UK
AIDS 15:S97-108. 2001..To estimate age- and sex-specific herpes simplex virus type-2 (HSV-2) prevalence in urban African adult populations and to identify factors associated with infection...
- HIV and male circumcision--a systematic review with assessment of the quality of studiesN Siegfried
South African Cochrane Centre, Medical Research Council, South Africa
Lancet Infect Dis 5:165-73. 2005..Although most studies show an association between male circumcision and prevention of HIV, these results may be limited by confounding, which is unlikely to be adjusted for...
- Speciation within Anopheles gambiae--the glass is half fullA Della Torre
Parasitology Unit, Department of Public Health, University of Rome La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
Science 298:115-7. 2002..Restrictions to gene flow among molecular forms of the mosquito Anopheles gambiae sensu stricto reveal an ongoing speciation process affecting the epidemiology of malaria in sub-Saharan Africa...
- School-based HIV prevention programmes for African youthMelanie Gallant
Department of Psychology, University of Windsor, 401 Sunset Ave Windsor, Ont, Canada N9B 3P4
Soc Sci Med 58:1337-51. 2004..Clearly, however, more research is needed to identify, with certainty, the factors that drive successful school-based HIV/AIDS risk reduction programmes in Africa...
- Antiretroviral therapy in resource-limited settings 1996 to 2006: patient characteristics, treatment regimens and monitoring in sub-Saharan Africa, Asia and Latin AmericaOlivia Keiser
Institute of Social and Preventive Medicine ISPM, University of Bern, Finkenhubelweg 11, 3012 Bern, Switzerland
Trop Med Int Health 13:870-9. 2008..To describe temporal trends in baseline clinical characteristics, initial treatment regimens and monitoring of patients starting antiretroviral therapy (ART) in resource-limited settings...
- Cardiovascular complications of diabetes mellitus in sub-Saharan AfricaAndre Pascal Kengne
Department of Internal Medicine and Specialities, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, BP 8046 Yaoundé, Cameroon
Circulation 112:3592-601. 2005..Two of 3 diabetic patients will die as a result of cardiovascular complications, and approximately 30% of patients treated in cardiovascular intensive care units have diabetes...
- Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV-tuberculosis coinfected populationsTed Cohen
Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, One Brigham Circle, 1620 Tremont Street, Boston, MA 02120, USA
Proc Natl Acad Sci U S A 103:7042-7. 2006....
- Towards an atlas of human helminth infection in sub-Saharan Africa: the use of geographical information systems (GIS)S Brooker
WHO Collaborating Centre, Wellcome Trust Centre for the Epidemiology of Infectious Disease, University of Oxford, South Parks Road, Oxford, UK OX1 3FY
Parasitol Today 16:303-7. 2000..In this article, Simon Brooker and colleagues describe progress made by this initiative in mapping helminth infections in sub-Saharan Africa, highlighting the value as well as the limitations of this empirical mapping approach...
- No room for complacency about adherence to antiretroviral therapy in sub-Saharan AfricaChristopher J Gill
Center for International Health and Development, Department of International Health, Boston University School of Public Health, MA 02118, USA
AIDS 19:1243-9. 2005....
- Orphanhood and childcare patterns in sub-Saharan Africa: an analysis of national surveys from 40 countriesRoeland Monasch
United Nations Children s Fund, New York, NY 10017, USA
AIDS 18:S55-65. 2004..Assess the impact of AIDS on prevalence of orphanhood and care patterns...
- Commercial sex and the spread of HIV in four cities in sub-Saharan AfricaL Morison
London School of Hygiene and Tropical Medicine, UK
AIDS 15:S61-9. 2001....
- Impact of malaria during pregnancy on low birth weight in sub-Saharan AfricaHelen L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
Clin Microbiol Rev 17:760-9, table of contents. 2004..These estimates imply that around 100,000 infant deaths each year could be due to LBW caused by malaria during pregnancy in areas of malaria endemicity in Africa...
- Acceptability of male circumcision for prevention of HIV/AIDS in sub-Saharan Africa: a reviewN Westercamp
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, 1603 W Taylor Street, MC 923, Chicago, IL 60612, USA
AIDS Behav 11:341-55. 2007..We recommend pilot interventions making safe circumcision services available in conjunction with current HIV prevention strategies and evaluating the safety and acceptability of circumcision...
- When to initiate highly active antiretroviral therapy in sub-Saharan Africa? A South African cost-effectiveness studyMotasim Badri
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town, South Africa
Antivir Ther 11:63-72. 2006..However, cost-effectiveness of initiating treatment at different CD4 count thresholds has not been explored in resource-poor settings...
- The potential impact of antiretroviral therapy on fertility in sub-Saharan AfricaAngela Kaida
Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, 5804 Fairview Avenue, Vancouver, British Columbia V6T 1Z3, Canada
Curr HIV/AIDS Rep 3:187-94. 2006..A conceptual framework is proposed to guide future research aimed at understanding how widespread use of ARV therapy may impact fertility in sub-Saharan Africa...
- Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan AfricaLaith J Abu-Raddad
Statistical Center for HIV Aids Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Science 314:1603-6. 2006..Hence, transient and repeated increases in HIV viral load resulting from recurrent co-infection with malaria may be an important factor in promoting the spread of HIV in sub-Saharan Africa...
- An appropriate research agenda for heart disease in AfricaPatrick Commerford
Cardiac Clinic, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, Western Cape, South Africa
Lancet 367:1884-6. 2006
- Dimensions of the emerging orphan crisis in sub-Saharan AfricaGeorge Bicego
Global AIDS Program, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E41, Atlanta, GA 30333, USA
Soc Sci Med 56:1235-47. 2003..Our results are interpreted in the context of societal responses to the crisis, and potential recommendations for intervention...
- Establishing valid AIDS monitoring and research in countries with generalized epidemicsStuart Brody
Institute of Medical Psychology and Behavioural Neurobiology, University of Tubingen, Germany
Int J STD AIDS 15:1-6. 2004..Multimethod approaches for developing sound HIV/AIDS research are presented...
- Study of bias in antenatal clinic HIV-1 surveillance data in a high contraceptive prevalence population in sub-Saharan AfricaSimon Gregson
Department of Infectious Disease Epidemiology, Imperial College School of Medicine, Norfolk Place, London W2 1PG, UK
AIDS 16:643-52. 2002..To describe patterns, sources and consequences of bias in antenatal clinic (ANC) HIV prevalence estimates in a high contraceptive prevalence population...
- Ecological and individual level analysis of risk factors for HIV infection in four urban populations in sub-Saharan Africa with different levels of HIV infectionB Auvert
INSERM U88, AP HP, A Paré, Saint Maurice, France
AIDS 15:S15-30. 2001..To identify factors that could explain differences in rate of spread of HIV between different regions in sub-Saharan Africa...
- Anesthesia for children in Sub-Saharan Africa--a description of settings, common presenting conditions, techniques and outcomesAboudoul Fataou Ouro-Bang'na Maman
Service of Anesthesia and Intensive Care, Lome Teaching Hospital, Togo
Paediatr Anaesth 19:5-11. 2009..Regarding pediatric surgery, the major workload is due to abdominal emergencies, mainly neonatal bowel obstruction or peritonitis due to typhoid perforation. The morbidity and mortality rate for these conditions is high...
- Concurrent sexual partnerships help to explain Africa's high HIV prevalence: implications for preventionDaniel T Halperin
Office of HIV AIDS, US Agency for International Development, Washington, DC 20523, USA
Lancet 364:4-6. 2004
- Mitochondrial footprints of human expansions in AfricaE Watson
School of Biological Sciences, Massey University, Palmerston North, New Zealand
Am J Hum Genet 61:691-704. 1997..Eurasian sequences are derived from essentially one sequence within this ancient cluster, even though a diverse mitochondrial pool was present in Africa at the time...
- Congenital Plasmodium falciparum malaria in sub-Saharan Africa: a rarity or frequent occurrence?C J Uneke
Department of Medical Microbiology, Faculty of Clinical Medicine, Ebonyi State University, PMB 053 Abakaliki, Nigeria
Parasitol Res 101:835-42. 2007..0 to 46.7%. Congenital malaria should be suspected and investigated in babies whose mothers are parasitemic, particularly if the babies are febrile...
- Urbanization in sub-saharan Africa and implication for malaria controlJennifer Keiser
Office of Population Research, Princeton University, Princeton, New Jersey, 08544, USA
Am J Trop Med Hyg 71:118-27. 2004..Mitigation of the current burden of malaria in urban African settings, in turn, is a necessity for stimulating environmentally and socially sustainable development...
- Tuberculosis and HIV interaction in sub-Saharan Africa: impact on patients and programmes; implications for policiesDermot Maher
Stop TB, World Health Organization, Geneva, Switzerland
Trop Med Int Health 10:734-42. 2005..This can help to ensure a firm evidence base for TB control policies aiming at the high standard of patient care that is at the heart of TB and HIV programmes...
- The cost-effectiveness of antenatal malaria prevention in sub-Saharan AfricaC A Goodman
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, United Kingdom
Am J Trop Med Hyg 64:45-56. 2001..However, extending the SP regimen to all gravidae and increasing the number of doses per pregnancy could make the intervention significantly less cost-effective...
- Meeting international goals in child survival and HIV/AIDSNeff Walker
Joint United Nations Programme on HIV AIDS, 20 Avenue Appia, 1211 Geneva, Switzerland
Lancet 360:284-9. 2002..We investigated this assumption by estimating HIV-attributable under-5 mortality in 39 countries in sub-Saharan Africa and comparing it to total mortality in children younger than 5 years between 1990 and 1999...
- Cost-effectiveness of malaria control in sub-Saharan AfricaC A Goodman
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, UK
Lancet 354:378-85. 1999..We used mathematical models to calculate cost-effectiveness ratios for the main prevention and treatment interventions in sub-Saharan Africa...
- Prospects for malaria eradication in sub-Saharan AfricaRicardo Aguas
Instituto Gulbenkian de Ciencia, Oeiras, Portugal
PLoS ONE 3:e1767. 2008..Accumulating epidemiological data constitute a valuable resource that must be intensively explored and interpreted as to effectively inform control planning...
- Human population genetic structure and inference of group membershipMichael J Bamshad
Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
Am J Hum Genet 72:578-89. 2003..This suggests that a more flexible framework is needed for making inferences about population structure and the utility of proxies...
- Contemporary trends in the epidemiology and management of cardiomyopathy and pericarditis in sub-Saharan AfricaBongani M Mayosi
Department of Medicine, J Floor Old Main Building, Groote Schuur Hospital, Observatory 7925, Cape Town, South Africa
Heart 93:1176-83. 2007....
- Unintended pregnancy in sub-Saharan Africa: magnitude of the problem and potential role of contraceptive implants to alleviate itDavid Hubacher
Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA
Contraception 78:73-8. 2008..Our aim was to estimate the number of unintended pregnancies in the region and model the impact of expanding use of contraceptive implants at the expense of short-term hormonal birth control methods...
- Health transitions in sub-Saharan Africa: overview of mortality trends in children under 5 years old (1950-2000)Michel Garenne
Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
Bull World Health Organ 84:470-8. 2006..To reconstruct and analyse mortality trends in children younger than 5 years in sub-Saharan Africa between 1950 and 2000...
- Antiretroviral drugs for tuberculosis control in the era of HIV/AIDSBrian G Williams
Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland
Science 301:1535-7. 2003..However, ARV drugs could enhance the treatment of TB, and TB programs provide an important entry point for the treatment of HIV/AIDS...
- Male circumcision for HIV prevention in sub-Saharan Africa: who, what and when?Richard G White
London School of Hygiene and Tropical Medicine, London, UK
AIDS 22:1841-50. 2008..We explore how the population-level impact of circumcision varies by target age group, coverage, time-to-scale-up, level of risk compensation and circumcision of HIV infected men...
- Scaling up antiretroviral therapy in Africa: learning from tuberculosis control programmes--the case of MalawiE Libamba
Department of Clinical Services, Ministry of Health, Lilongwe, Malawi
Int J Tuberc Lung Dis 9:1062-71. 2005..We hope that by using the DOTS approach we will be able to deliver ART to large numbers of HIV-infected patients under controlled conditions, and minimise the risk of developing drug resistance...
- Noncommunicable diseases in sub-Saharan Africa: where do they feature in the health research agenda?N Unwin
Department of Diabetes, University of Newcastle, Medical School, England
Bull World Health Organ 79:947-53. 2001..Research is needed to guide improvements in the clinical and cost effectiveness of resources currently committed to the care of patients with noncommunicable diseases, and to direct and evaluate preventive measures...
- Multicentre study on factors determining differences in rate of spread of HIV in sub-Saharan Africa: methods and prevalence of HIV infectionA Buve
Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
AIDS 15:S5-14. 2001....
- The challenges of involving traditional healers in HIV/AIDS careE Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada, and Department of Medicine, University of Calabar Teaching Hospital, Nigeria
Int J STD AIDS 17:360-3. 2006..Collaboration is essential, given the changing epidemic of HIV and the dynamic relationship between the two health sectors...
- Brief communication: mtDNA variation in North Cameroon: lack of Asian lineages and implications for back migration from Asia to sub-Saharan AfricaValentina Coia
Department of Animal and Human Biology, University La Sapienza, 00185 Rome, Italy
Am J Phys Anthropol 128:678-81. 2005....
- Cost effectiveness analysis of strategies for maternal and neonatal health in developing countriesTaghreed Adam
Health Systems Financing, Evidence and Information for Policy, World Health Organization, Switzerland
BMJ 331:1107. 2005..To determine the costs and benefits of interventions for maternal and newborn health to assess the appropriateness of current strategies and guide future plans to attain the millennium development goals...
- Achieving the Millennium Development GoalsAlan Fenwick
Lancet 365:1029-30. 2005
- Malaria attributable to the HIV-1 epidemic, sub-Saharan AfricaEline L Korenromp
World Health Organization, Geneva, Switzerland
Emerg Infect Dis 11:1410-9. 2005..These effects were due to high HIV-1 prevalence in rural areas and the locally unstable nature of malaria transmission that results in a high proportion of adult cases...
- Safety, efficacy and determinants of effectiveness of antimalarial drugs during pregnancy: implications for prevention programmes in Plasmodium falciparum-endemic sub-Saharan AfricaRobert D Newman
Malaria Epidemiology Branch, Division of Parasitic Diseases, NCID, CDC, Atlanta, GA 30341, USA
Trop Med Int Health 8:488-506. 2003....
- Urban-rural differentials in child malnutrition: trends and socioeconomic correlates in sub-Saharan AfricaJean Christophe Fotso
African Population and Health Research Center, 00100 GPO, Nairobi, Kenya
Health Place 13:205-23. 2007..These urban-rural gaps are abolished in almost all countries when SES is controlled. These results suggest that policies and programs contributing to the attainment of the MDGs should pay particular attention to the urban poor...
- Focus on women: linking HIV care and treatment with reproductive health services in the MTCT-Plus InitiativeLandon Myer
Columbia University, Mailman School of Public Health, New York, NY, USA
Reprod Health Matters 13:136-46. 2005....
- The protective effect of male circumcision as a faith lift for the troubled paradigm of HIV epidemiology in sub-Saharan AfricaJohn J Potterat
PLoS Med 3:e64; author reply e67. 2006
- HIV and Islam: is HIV prevalence lower among Muslims?Peter B Gray
Department of Anthropology, Peabody Museum, Harvard University, 11 Divinity Avenue, Cambridge, MA 02138, USA
Soc Sci Med 58:1751-6. 2004..g., vs. extramarital affairs) and other factors, but that benefits arising from circumcision may help account for lower HIV prevalence among Muslims...
- Early marriage and HIV risks in sub-Saharan AfricaShelley Clark
University of Chicago, 1155 East 60th Street, Chicago, IL 60637, USA
Stud Fam Plann 35:149-60. 2004..These results challenge commonly held assumptions about sex within marriage...
- Variation of female and male lineages in sub-Saharan populations: the importance of sociocultural factorsGiovanni Destro-Bisol
Department of Animal and Human Biology, University La Sapienza, Rome, Italy
Mol Biol Evol 21:1673-82. 2004....
- HIV prevalence and trends in sub-Saharan Africa: no decline and large subregional differencesEmil Asamoah-Odei
WHO Regional Office for Africa, Harare, Zimbabwe
Lancet 364:35-40. 2004..However, only analysis of surveillance data from the same populations over time can provide insight into trends of HIV prevalence. We have used data from the same antenatal clinics to document recent empirical trends...
- The potential impact of male circumcision on HIV in Sub-Saharan AfricaBrian G Williams
World Health Organization, Stop TB Department, Geneva, Switzerland
PLoS Med 3:e262. 2006..We explore the implications of this finding for the promotion of MC as a public health intervention to control HIV in sub-Saharan Africa...
- Male circumcision and HIV infection in four cities in sub-Saharan AfricaB Auvert
INSERM U88, AP HP, A Paré, France
AIDS 15:S31-40. 2001..To explore the role of male circumcision in the spread of HIV infection in four urban populations in sub-Saharan Africa...
- Mitochondrial DNA analysis of northwest African populations reveals genetic exchanges with European, near-eastern, and sub-Saharan populationsJ C Rando
Departamento de Genetica, Universidad de La Laguna, Tenerife
Ann Hum Genet 62:531-50. 1998..The Mauritanians and West-Saharans, in contrast, bear substantial though not dominant mtDNA affinity with sub-Saharans...
- Medicine sellers and malaria treatment in sub-Saharan Africa: what do they do and how can their practice be improved?Catherine Goodman
Health Economics and Financing Programme, Health Policy Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
Am J Trop Med Hyg 77:203-18. 2007..Interventions must be adapted to include artemisinin-based combination therapies, and their sustainability and potential to operate at a national level should be further explored...
- Bantu language trees reflect the spread of farming across sub-Saharan Africa: a maximum-parsimony analysisClare Janaki Holden
Department of Anthropology, University College London, Gower Street, London WC1E 6BT, UK
Proc Biol Sci 269:793-9. 2002..This suggests that the major subgroups of modern Bantu stem from the Neolithic and Early Iron Age, with little subsequent movement by speech communities...
- Assessing the role of anal intercourse in the epidemiology of AIDS in AfricaStuart Brody
Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Germany
Int J STD AIDS 14:431-6. 2003....
- Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant populationR W Snow
Kenya Medical Research Institute KEMRI Wellcome Trust, Collaborative Programme, Nairobi, Kenya
Bull World Health Organ 77:624-40. 1999....
- Preventing antiretroviral anarchy in sub-Saharan AfricaA D Harries
National Tuberculosis Control Programme, Community Health Science Unit, Lilongwe, Malawi
Lancet 358:410-4. 2001..Poor adherence to treatment leads to the emergence of drug-resistant viral strains that need new combinations of drugs or new drugs altogether...
- Late marriage and the HIV epidemic in sub-Saharan AfricaJohn Bongaarts
Population Council, New York, NY 10017, USA
Popul Stud (Camb) 61:73-83. 2007..These findings support the hypothesis of a link between a high average age at marriage and a long period of premarital intercourse during which partner changes are relatively common and facilitate the spread of HIV...
- Interpreting sexual behaviour data: validity issues in the multicentre study on factors determining the differential spread of HIV in four African citiesA Buve
Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
AIDS 15:S117-26. 2001....
- Schistosomes, snails and satellitesS Brooker
Department of Infectious Disease Epidemiology, Imperial College School of Medicine, Norfolk Place, W2 1PG, London, UK
Acta Trop 82:207-14. 2002..Finally, the current practical application of GIS and remote sensing are reviewed in the context of national control programmes...
- Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic reviewSydney Rosen
Center for International Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America
PLoS Med 4:e298. 2007..In this paper we present a systematic review of patient retention in ART programs in sub-Saharan Africa...
- Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectivenessKefas Mugittu
Ifakara Health Research and Development Centre, Ifakara, Tanzania
Trop Med Int Health 11:1350-9. 2006..Our findings support the WHO recommendation of PCR genotyping in malaria clinical trials and suggest that stepwise genotyping of only two loci (msp2 and msp1 or glurp) can reliably discriminate recrudescences from new infections...
- [Ophidian envenomations and emergencies in Sub-Saharan Africa]J P Chippaux
IRD, Dakar, Senegal
Bull Soc Pathol Exot 98:263-8. 2005..Thus, it is expected to reduce by 90% the mortality rate in the next ten years...
- Hyperreactive malaria in expatriates returning from sub-Saharan AfricaJ van den Ende
Institute of Tropical Medicine, Antwerp, Belgium University Hospital Antwerp, Edegem, Belgium
Trop Med Int Health 5:607-11. 2000....
- Malaria and helminth interactions in humans: an epidemiological viewpointT W Mwangi
Kenya Medical Research Institute, Centre for Geographic Medicine and Research, P O Box 230, 80108 Kilifi, Kenya
Ann Trop Med Parasitol 100:551-70. 2006..Future studies that might be considered, in order to address the gaps in knowledge, are also considered...
- Managing tuberculosis and HIV in sub-Sahara AfricaUmesh G Lalloo
Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella 4013, Durban, South Africa
Curr HIV/AIDS Rep 5:132-9. 2008..Combining HIV and TB care has the potential to bring additional infrastructural and human resources to the respective programs, with synergistic benefits...
- Eradicating chancroidR Steen
Family Health International, 2101 Wilson Boulevard, Suite 700, Arlington, VA 22201, USA
Bull World Health Organ 79:818-26. 2001..Protecting sex workers and their clients from exposure to sexually transmitted diseases (STDs) and improving curative services for STDs are among the proven strategies that could be employed...
- Rubbery figures?Michael Glass
PLoS Med 3:e70. 2006
- Paediatric surgery in the Third WorldG P Hadley
S Afr Med J 96:1139-40. 2006
- Can behavior change explain increases in the proportion of genital ulcers attributable to herpes in sub-Saharan Africa? A simulation modeling studyEline L Korenromp
Department of Public Health, Faculty of Medicine, Erasmus University Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
Sex Transm Dis 29:228-38. 2002..The proportion of cases of genital ulcer disease attributable to herpes simplex virus type 2 (HSV-2) appears to be increasing in sub-Saharan Africa...
- Predictors of stillbirth in sub-saharan AfricaBenjamin H Chi
Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
Obstet Gynecol 110:989-97. 2007..To describe the incidence and predictors of stillbirth in a predominantly human immunodeficiency virus (HIV)-infected African cohort...
- Community attitudes towards sexual activity and childbearing by HIV-positive people in South AfricaL Myer
Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, South Africa
AIDS Care 18:772-6. 2006..Health policies and services are required to reinforce the reproductive rights of HIV-infected individuals in South Africa and other countries in sub-Saharan Africa where HIV is most prevalent...
- HIV and sexually transmitted infections among women presenting at urban primary health care clinics in two cities of sub-Saharan AfricaElizabeth Mukuze Mbizvo
Department of Obstetrics and Gynaecology, The National Hospital, University of Oslo N 0027 Oslo, Norway
Afr J Reprod Health 9:88-98. 2005..3% compared to 11.5% in Tanzania (p < 0.01). Interventions should target identified risk factors with particular attention to youths...
- Potential impact of adjustment policies on vulnerability of women and children to HIV/AIDS in sub-Saharan AfricaRoberto De Vogli
Department of Epidemiology and Public Health, University College of London, 1 19 Torrington Place, London WC1E 6BT
J Health Popul Nutr 23:105-20. 2005..Given the potential for adjustment policies to exacerbate the AIDS pandemic among women and children, a careful examination of the effects of these policies on maternal and child welfare is urgently needed...
- Medical migration and Africa: an unwanted legacy of educational changePeter Bundred
Department of Primary Care, University of Liverpool, UK
Med Teach 29:893-6. 2007....
- Reconsidering the impact of conflict on HIV infection among women in the era of antiretroviral treatment scale-up in sub-Saharan Africa: a gender lensKate Shannon
Faculty of Medicine, School of Population and Public Health, British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Vancouver, Canada
AIDS 22:1705-7. 2008
- Is HIV control in sub-Saharan Africa losing focus?: the need for simplified, prioritized prevention strategiesStefan Hanson
IHCAR, Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
Scand J Public Health 33:233-5. 2005
- Integrating family planning and prevention of mother-to-child HIV transmission in resource-limited settingsAnn Duerr
Centers for Disease Control and Prevention, Atlanta, GA, USA
Lancet 366:261-3. 2005
- Impact of orphanhood on underweight prevalence in sub-Saharan AfricaJonathan Rivers
Department of International Health and Development, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
Food Nutr Bull 29:32-42. 2008..Although evidence indicates that orphans risk losing opportunities for adequate education, health care, and future employment, the immediate effects of orphanhood on child nutritional status remain poorly understood...
- [Male circumcision--an evidence-based preventive measure]Nicolai Lohse
Ugeskr Laeger 170:2359; author reply 2360. 2008
- Comparison of HIV prevalence estimates from antenatal care surveillance and population-based surveys in sub-Saharan AfricaL S Montana
Department of Global Health and Population, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
Sex Transm Infect 84:i78-i84. 2008....
- Ion transport and motility in larval mosquito stomachDavid F Moffett; Fiscal Year: 2010..Analyses of peristalsis and its regulation with electrophysiological techniques and image analyses. The results of this project will provide information about specific targets for the development of mosquito control agents. ..
- Cell Biology of Mycobacterium tuberculosis InfectionDavid G Russell; Fiscal Year: 2010..tuberculosis. We propose determining how the bacterium's metabolism is realigned to access these carbon sources. ..
- Social Network Intervention to Engage Out-of-Care PLH Into TreatmentJeffrey A Kelly; Fiscal Year: 2013..The study's impact rests on the potential for network interventions to engage PLH in the community to enter and adhere to care. The modality will be applicable to international settings and in the United States. ..
- IMPLEMENTATION RESEARCH FOR MANAGEMENT OF MALARIA AND CHILDHOOD ILLNESS/TANZANIASALIM MOHAMMED KHAMIS ABDULLA; Fiscal Year: 2013..Details of the research plan are outlined in the continuation pages. ..
- Microbial Mediation of Habitat Selection and ProductionEdward Walker; Fiscal Year: 2006..Microbial basis for larval habitat production will be studied with field and lab experiments where nutrient sources and microbial communities are quantified, manipulated and larval growth responses and adult production quantified. ..
- SPECIES BOUNDARIES IN THE ANOPHELES GAMBIAE COMPLEXNora Besansky; Fiscal Year: 2003It is children living in Africa south of the Sahara that bear the brunt of morbidity and mortality caused by Plasmodium falciparum...
- Insecticide mosaics and sustainability of treated netsEdward Walker; Fiscal Year: 2007..Industry partners Vestergaard-Frandsen and Syngenta are directly involved in these efforts, for formulation and evaluation purposes. ..
- Practical Diagnostics for AIDS-Related Pediatric TB,PeruRichard Oberhelman; Fiscal Year: 2006..These new diagnostic methods have tremendous potential to improve and simplify the diagnosis of pediatric tuberculosis in low-income countries with limited laboratory resources. ..
- Overcoming TB and AIDSAndrew Robertson; Fiscal Year: 2009....
- Trypanosome gene expression in tsetseSerap Aksoy; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Paraspinal Denervation in Low Back PainAndrew J Haig; Fiscal Year: 2010..The results will help doctors avoid unnecessary surgery and help scientists to understand more about how spinal stenosis disables so many older people. ..
- HOOKWORM LARVAL INFECTIVITY AND DEVELOPMENTPeter Hotez; Fiscal Year: 2002..The pharmacologic manipulation of parasite-derived protein kinases may offer a new approach to chemotherapy by taking larvae out of arrest. ..
- PARASPINAL MUSCLE DENERVATION AND SYMPTOMS IN LUMBAR SSAndrew Haig; Fiscal Year: 2005..Subjects will repeat the test battery (MRI, EMG, and clinical evaluation) approximately 18 months later. Appropriate statistics will test each of the four hypotheses. ..
- Community factors shaping the sexual behavior of malesRobert Stephenson; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..
- Oxidative Stress Markers and HIV DementiaNed Sacktor; Fiscal Year: 2009..We believe that oxidative stress plays a significant role in the development of HIV-D, and strategies to decrease oxidative stress may serve as a useful therapeutic target to treat HIV-D. ..
- Community Influences on Young People's HIV/AIDS Knowledge, Attitudes & PracticesRobert Stephenson; Fiscal Year: 2007..unreadable] [unreadable]..
- Prevalence, risk factors and consequences of complex M. Tuberculosis infectionsTheodore Cohen; Fiscal Year: 2010..The overall goal of this study is to learn more about the natural history of TB and to use this knowledge to improve the health of individuals and their communities. ..
- Natural History and Pathogenesis of WNV in Viremic Dono*Michael Busch; Fiscal Year: 2007..abstract_text> ..
- GP46 GENES AND PROTEIN EXPRESSION IN LEISHMANIA CHAGASIJOHN DONELSON; Fiscal Year: 2002....
- Plainning malaria training in Zambia Thomas Eisele; Fiscal Year: 2009..Tailoring a sustainable program using appropriate technology and a framework of collaboration in support of PMI activities will greatly increase the likelihood of controlling, and perhaps eventually eliminating, malaria in Zambia. ..
- Micro and Macro Causes of Trends in Youth SmokingFred Pampel; Fiscal Year: 2004..The aims further reflect a change in the principal investigator's interests to behavioral research in cancer control. ..
- Influences on Adherence to ARVs in UgandaNorma Ware; Fiscal Year: 2007..Practical intervention strategies will be derived as the basis for intervention design and testing, which follow as next steps from this research. [unreadable] [unreadable] [unreadable]..
- Comparitive Antipsychotic Drug Actions on Brain NeurochemistryCarol Tamminga; Fiscal Year: 2007..Concentration on mouse behaviors, neurochemistry and behavior will advance studies aimed at kinetic applications. ..
- HIV PREVENTION TRIAL UNIT (PRIDE NYC PROGRAM)Wafaa El Sadr; Fiscal Year: 2006..abstract_text> ..
- UAB-ZAMBIA-HAITI HIV PREVENTION TRIALS UNITJeffrey Stringer; Fiscal Year: 2006..Since other research and service funding supports these cohorts, the costs to maintain them prior to trials beginning are minimal. ..
- co-Trimoxazole in Zambian Infants (TZI)CHRISTOPHER GILL; Fiscal Year: 2007..abstract_text> ..
- Molecular approaches for understanding TB dynamicsTheodore Cohen; Fiscal Year: 2008..It is our hope that better analytic techniques will allow for more accurate assessments of treatment and prevention. [unreadable] [unreadable]..
- Adaptive evolution of pathogenesis towards symbiosisSerap Aksoy; Fiscal Year: 2009..The role of functions typically associated with pathogenic microorganisms will be pursued in these beneficial microbes. ..
- SCienceLabBert Ely; Fiscal Year: 2010..To address this problem, SCienceLab provides an opportunity for students to spend a day experiencing research and interacting with students who are working in a biomedical research laboratory. ..
- Mechanisms and clinical effects of microchimerism in transfused trauma patientsMICHAEL PAUL BUSCH; Fiscal Year: 2010..TA-MC also offers an opportunity to better understand, and potentially exploit, injury-induced tolerance for future therapeutic purposes. ..
- Social Course of Adherence to HAART in Active Drug UsersNorma Ware; Fiscal Year: 2003..These categories will serve as the basis for formulating and assessing the feasibility of patient focused, clinician-focused, and other strategies for supporting adherence to HAART among active users of illegal drugs. ..
- Gender, power, and susceptibility to STDs/HIV in IndiaSuneeta Krishnan; Fiscal Year: 2009....
- KILLER CELLS & VIRAL LOAD IN VERTICAL HIV INFECTIONKatherine Luzuriaga; Fiscal Year: 2009..Data from these studies will improve our understanding of the pathogenesis of early pediatric HIV infection and contribute to the development of strategies to prevent or modify pediatric HIV-1 infection. ..
- Is Cerebral Malaria a Risk Factor for Epilepsy?Gretchen Birbeck; Fiscal Year: 2008..Terrie Taylor resides. ..
- Routine HIV Testing Among Adolescents and the Shifting Culture of AIDSLori Leonard; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- HARLEM AIDS TREATMENT GROUP-'CPCRA'Wafaa El Sadr; Fiscal Year: 2006..They also are committed to the conduct of large long-term studies as a means of answering key questions in HIV management that cannot be answered through shorter trials. ..
- TUBERCULOSIS ADHERENCE PARTNERSHIP ALLIANCE STUDYWafaa El Sadr; Fiscal Year: 2004..abstract_text> ..
- A Community Study of Infertility in Northern TanzaniaUlla Larsen; Fiscal Year: 2004..A basic protocol for the recommended treatment of infertility will be developed. 6. To analyze the social implications of infertility. 7. To assess the demographic implications of infertility. ..
- CLINICAL RESEARCH CURRICULUMThomas Pearson; Fiscal Year: 2004..With completion of the RCRC, the trainee should have the theoretical, methodological, and practical knowledge and skills for a productive career in clinical research. ..
- Prophylactic Ibuprofen: Effect on IUD Continuation RatesDavid Hubacher; Fiscal Year: 2003..In the US, ibuprofen may help spur renewed interest in the most cost effective and efficacious reversible contraceptive method available. ..
- Improving Hypertension Treatment in AfricaRichard Cooper; Fiscal Year: 2003..Whether our project yields a "positive" or "negative" result in relation to the main goal of identifying an effective clinical method, the outcome will have far-reaching implications for health care policy in that region. ..
- Behavioral factors and dietary change in WHTFSMPAlok Bhargava; Fiscal Year: 2003..Overall, the results will facilitate the design of policies for improving health of especially minority women in the United States and will be useful for analyses of the Women's Health Initiative data. ..
- HEPATITIS C VIRAL QUASISPECIES WITHIN THE LIVERAdrian Di Bisceglie; Fiscal Year: 2003..These studies have great potential significance for understanding of viral clearance, development of persistent infection and for the development of a vaccine against HCV. ..
- PARTIAL DOPAMINEAGONIST TREATMENT OF SCHIZOPHRENIACarol Tamminga; Fiscal Year: 2002..These data will predict and later help us to select optimal agonist intrinsic activity ior clinical testing for antipsychotic actvity, duration of therapeutic action, and side effects. ..
- BRIEF HIV RISK REDUCTION COUNSELINGSeth Kalichman; Fiscal Year: 2002..Results of the proposed study will guide the allocation of HIV prevention resources in establishing brief and effective HIV risk reduction counseling services for populations vulnerable to HIV infection. ..
- UNIVERSITY OF ROCHESTER NUTRITION ACADEMIC AWARD PROGRAMThomas Pearson; Fiscal Year: 2002..Dissemination of the curriculum and educational tools will be facilitated by programs in professional societies, collaboration with the food industry, and development of an easily accessible Website. ..
- INTERACTION OF TSETSE--ITS SYMBIONTS AND TRYPANOSOMESSerap Aksoy; Fiscal Year: 2001..The basic knowledge obtained will strengthen our understanding of tsetse biology and will also provide information relevant to other important disease vectors which harbor similar symbionts (e.g., ticks, fleas, reduviid bugs etc.). ..
- Telomere structure and function in Trypanosoma bruceiGEORGE CROSS; Fiscal Year: 2005..There are significant similarities between the telomeres of trypanosomes and humans, so trypanosomes would be a useful model in which to study events that are relevant to human aging and cancer. ..
- MALARIA AND HIV IN PREGNANT WOMEN IN MALAWISteven Meshnick; Fiscal Year: 2005..The results of this study will have important implications for designing public health program s for antenatal care in African and should promote our understanding of the pathogenesis of MTCT. ..
- Gender Violence and HIV Risk Reduction in South AfricaLeickness Simbayi; Fiscal Year: 2007..unreadable] [unreadable]..
- Impact of HIV-related infections and ART in South AfricaCharles Holmes; Fiscal Year: 2006..He is mentored by two senior investigators with an extremely strong record of mentoring junior investigators and guiding them to become successful physician scientists. ..
- New model for describing and projecting adult mortalityJohn Bongaarts; Fiscal Year: 2006..4) Test the new projection method by comparing its results with projections produced by the Lee-Carter procedure. [unreadable] [unreadable]..
- PEDIATRIC AIDS CLINICAL TRIAL UNITKatherine Luzuriaga; Fiscal Year: 2006..abstract_text> ..
- Examination of the Limbic Cortex in SchizophreniaCarol Tamminga; Fiscal Year: 2006..These data will have implications for understanding the mechanisms of the illness and for directing future new drug discovery for schizophrenia therapeutics. ..
- SEVERE MALARIA IN AFRICAN CHILDREN: A CLINICAL NETWORKTerrie Taylor; Fiscal Year: 2004..Given the enormous toll of malaria, this could re resent a significant decline in the death rate across sub-Saharan Africa. ..
- Epilepsy-associated stigma in ZambiaGretchen Birbeck; Fiscal Year: 2005..This contextual framework will facilitate the development of effective, community-based interventions aimed at improving the lives of people with epilepsy in the region. ..
- Early Nutrition, Human Capital and Economic ProductivityReynaldo Martorell; Fiscal Year: 2005..The three participating institutions have a successful history of previous collaboration in complex field studies and other research. ..
- AMASTIN/TUZIN GENE CLUSTER OF TRYPANOSOMA CRUZIJOHN DONELSON; Fiscal Year: 2001..Finally, we will assess whether amastin and/or tuzin can serve a target antigens for an improved diagnostic test for T. cruzi infection. ..
- Intervention to Close Digital Divide in AIDS CareSeth Kalichman; Fiscal Year: 2004..If successful, the experimental intervention could be readily implemented as a community-based program by AIDS Service Organizations, health centers, and community-based Internet access providers. ..
- Natural history of acute and chronic HCV in blood donorsMichael Busch; Fiscal Year: 2008..These investigations will yield important insights into HCV pathogenesis and clarify the natural history of disease for the large number of HCV infected persons identified through donor screening. ..
- Building Partnerships to Reduce Youth HIV Risk in AfricaAkinrinola Bankole; Fiscal Year: 2006..The expanded activities would also increase the potential of the Research Project to have an impact on policy and programs and to improve prevention of HIV among youth in Sub-Saharan Africa. ..
- Forensic Detection of Salmonella Resistance and SubtypeLee Harrison; Fiscal Year: 2005..enterica and 2) molecular methods for rapid outbreak detection among S. enterica serovars. ..