kaposi varicelliform eruption

Summary

Summary: A disseminated vesicular-pustular eruption caused by the herpes simplex virus (HERPESVIRUS HOMINIS), the VACCINIA VIRUS, or Varicella zoster (HERPESVIRUS 3, HUMAN). It is usually superimposed on a preexisting, inactive or active, atopic dermatitis (DERMATITIS, ATOPIC).

Top Publications

  1. ncbi Relapsing Kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis
    Midori Ambo
    Acta Derm Venereol 82:224-5. 2002
  2. ncbi Exacerbation of atopic dermatitis in the emergency department
    Frederic Feye
    Emergency Department Department of Dermatology, Universite Catholique de Louvain, Mont Godinne Hospital, B 5530 Yvoir, Belgium
    Eur J Emerg Med 11:360-2. 2004
  3. ncbi [Eczema herpeticum: Pathogenesis and therapy]
    H C Rerinck
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337 München
    Hautarzt 57:586-91. 2006
  4. ncbi Visual diagnosis: an 8-month-old infant who has an erupting rash
    Tamar Stricker
    University Children s Hospital, Zurich, Switzerland
    Pediatr Rev 28:231-4. 2007
  5. ncbi Rapidly increasing incidence of Kaposi's varicelliform eruption in patients with atopic dermatitis
    Hajime Kimata
    Indian J Dermatol Venereol Leprol 74:260-1. 2008
  6. pmc Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum
    Yuko Kawakami
    Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA
    J Exp Med 206:1219-25. 2009
  7. pmc Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response
    Donald Y M Leung
    Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    J Allergy Clin Immunol 127:965-73.e1-5. 2011
  8. pmc The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections
    Michael D Howell
    Department of Pediatrics, National Jewish Health, Denver, Colo 80206, USA
    J Allergy Clin Immunol 128:1006-14. 2011
  9. ncbi Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
    Pei Song Gao
    Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Allergy Clin Immunol 124:507-13, 513.e1-7. 2009
  10. pmc Cathelicidin deficiency predisposes to eczema herpeticum
    Michael D Howell
    Division of Allergy and Immunology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    J Allergy Clin Immunol 117:836-41. 2006

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Detail Information

Publications113 found, 100 shown here

  1. ncbi Relapsing Kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis
    Midori Ambo
    Acta Derm Venereol 82:224-5. 2002
  2. ncbi Exacerbation of atopic dermatitis in the emergency department
    Frederic Feye
    Emergency Department Department of Dermatology, Universite Catholique de Louvain, Mont Godinne Hospital, B 5530 Yvoir, Belgium
    Eur J Emerg Med 11:360-2. 2004
    ..The association with herpetic keratitis is not frequent but is a major ophthalmological problem. Treatment consists of the administration of high-dose intravenous acyclovir and acyclovir ophthalmic ointment...
  3. ncbi [Eczema herpeticum: Pathogenesis and therapy]
    H C Rerinck
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337 München
    Hautarzt 57:586-91. 2006
    ..Treatment of choice is systemic acyclovir therapy...
  4. ncbi Visual diagnosis: an 8-month-old infant who has an erupting rash
    Tamar Stricker
    University Children s Hospital, Zurich, Switzerland
    Pediatr Rev 28:231-4. 2007
  5. ncbi Rapidly increasing incidence of Kaposi's varicelliform eruption in patients with atopic dermatitis
    Hajime Kimata
    Indian J Dermatol Venereol Leprol 74:260-1. 2008
  6. pmc Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum
    Yuko Kawakami
    Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA
    J Exp Med 206:1219-25. 2009
    ..Given low NK cell activities and increased IL-17 expression in atopic dermatitis patients, these results can explain the increased susceptibility of atopic dermatitis patients to eczema vaccinatum...
  7. pmc Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response
    Donald Y M Leung
    Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    J Allergy Clin Immunol 127:965-73.e1-5. 2011
    ..The basis for increased susceptibility of patients with atopic dermatitis (AD) to develop disseminated viral skin infections such as eczema herpeticum (AD with a history of eczema herpeticum, ADEH(+)) is poorly understood...
  8. pmc The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections
    Michael D Howell
    Department of Pediatrics, National Jewish Health, Denver, Colo 80206, USA
    J Allergy Clin Immunol 128:1006-14. 2011
    ..Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with increased susceptibility to recurrent skin infections...
  9. ncbi Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
    Pei Song Gao
    Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Allergy Clin Immunol 124:507-13, 513.e1-7. 2009
    ..Associations have not been reported in African ancestry populations. Atopic dermatitis eczema herpeticum (ADEH) is a rare but serious complication of AD resulting from disseminated cutaneous herpes simplex virus infections...
  10. pmc Cathelicidin deficiency predisposes to eczema herpeticum
    Michael D Howell
    Division of Allergy and Immunology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    J Allergy Clin Immunol 117:836-41. 2006
    ..Eczema herpeticum (ADEH) develops in a subset of patients with atopic dermatitis (AD) because of disseminated infection with herpes simplex virus (HSV)...
  11. ncbi Viral infections in atopic dermatitis: pathogenic aspects and clinical management
    Andreas Wollenberg
    Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
    J Allergy Clin Immunol 112:667-74. 2003
    ..Eczema herpeticum is the most common member of this group; recent advances in understanding its pathogenesis might contribute to a more successful management of this serious complication...
  12. ncbi Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases
    Andreas Wollenberg
    Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
    J Am Acad Dermatol 49:198-205. 2003
    ..Objective and methods We sought to characterize the clinical features and predisposing factors for EH. A retrospective analysis of 100 patients with EH seen from 1980 through 1996 and of 105 control patients with AD was performed...
  13. ncbi Smallpox vaccination: Risk considerations for patients with atopic dermatitis
    Renata J M Engler
    Walter Reed Army Medical Center, Allergy Immunology Department, Washington, DC, USA
    J Allergy Clin Immunol 110:357-65. 2002
    ..Individuals with active or quiescent atopic dermatitis are at increased risk for vaccinia complications. The nature of these complications and other considerations are summarized in this rostrum...
  14. ncbi Kaposi varicelliform eruption (eczema herpeticum)
    Jonathan Olson
    Department of Medicine, University of Washington School of Medicine, Seattle, WA 98105, USA
    Dermatol Online J 14:18. 2008
    ..Antiviral treatment for eczema herpeticum is very effective, and should be instituted without delay to avoid significant morbidity and mortality...
  15. ncbi Secondary bacterial infections complicating skin lesions
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    J Med Microbiol 51:808-12. 2002
    ..These organisms probably reached these sites from the oral cavity, where they are part of the normal flora. This review highlights the polymicrobial aerobic-anaerobic microbiology of secondarily infected skin lesions...
  16. pmc Phenotype of atopic dermatitis subjects with a history of eczema herpeticum
    Lisa A Beck
    Department of Dermatology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Allergy Clin Immunol 124:260-9, 269.e1-7. 2009
    ..A subset of subjects with atopic dermatitis (AD) are susceptible to serious infections with herpes simplex virus, called eczema herpeticum, or vaccina virus, called eczema vaccinatum...
  17. pmc A 33-year-old man with a facial rash
    John Fleming
    Imperial College, London, United Kingdom
    PLoS Med 1:e17; quiz e12. 2004
  18. ncbi Treatment of ocular disease in eczema herpeticum
    T P Margolis
    F I Proctor Foundation, University of California, San Francisco
    Am J Ophthalmol 110:274-9. 1990
    ..The combined use of systemic acyclovir and topical trifluridine may be of similar value in treating all cases of atopic herpetic keratitis...
  19. ncbi Eczema herpeticum: a dermatologic emergency
    Christine L Mackley
    Penn State Hershey Medical Center, Hershey, PA, USA
    Dermatol Nurs 14:307-10, 323; quiz 313. 2002
    ..Two representative cases of eczema herpeticum along with discussion of the etiology, means of diagnosis, treatments, and complications of eczema herpeticum are presented...
  20. ncbi A case of Kaposi varicelliform eruption in Darier-White disease
    Alyssa A Donnelly
    Branch Medical Clinic Everett, Washington, USA
    Cutis 75:33-6. 2005
    ..Patients with DWD are prone to frequent superinfection including the rare complication of Kaposi varicelliform eruption. It is postulated that a defect in cell-mediated immunity may contribute to this predisposition.
  21. ncbi Kaposi's varicelliform eruption
    Manjunath M Shenoy
    Department of Skin and VD, K S Hegde Medical Academy, Deralakatte, Mangalore, India
    Indian J Dermatol Venereol Leprol 73:65. 2007
    ..There was history of fever, malaise and extensive vesicular eruptions. Diagnosis was made based on clinical features and Tzanck smear examination. Patient responded adequately to oral acyclovir therapy...
  22. ncbi Kaposi's varicelliform eruption in a patient with phenytoin-induced drug rash
    C Ajith
    Int J Dermatol 45:1452-3. 2006
  23. ncbi Eczema vaccinatum as an adverse event following exposure to vaccinia virus: case definition & guidelines of data collection, analysis, and presentation of immunization safety data
    Patricia Nell
    Airforce Reserve Command, United States Air Force, Sturgeon Bay, WI, USA
    Vaccine 25:5725-34. 2007
  24. ncbi Current aspects of innate and adaptive immunity in atopic dermatitis
    Andreas Wollenberg
    Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Frauenlobstr 9 11, 80337, Munich, Germany
    Clin Rev Allergy Immunol 33:35-44. 2007
    ..Molluscum contagiosum virus produces a unique IL-18 binding protein to evade antiviral defense mechanisms. Innate and adaptive immunity do not simply coexist but are linked to one another in a complex network of skin immunobiology...
  25. ncbi [Vesicular/pustular lesions in a patient with atopic dermatitis]
    Rosa Gimenez
    Sección de Dermatología Hospital Universitario Río Hortega Valladolid España
    Enferm Infecc Microbiol Clin 21:269-70. 2003
  26. ncbi Public health. Treating vaccine reactions: two lifelines, but no guarantees
    Martin Enserink
    Science 298:2313. 2002
  27. ncbi Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum
    Michael D Howell
    Division of Allergy and Immunology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Immunol 172:1763-7. 2004
    ..01). These data support a role for cathelicidins in the inhibition of orthopox virus (vaccinia) replication both in vitro and in vivo. Susceptibility of patients with AD to eczema vaccinatum may be due to a deficiency of cathelicidin...
  28. ncbi Close association of predominant genotype of herpes simplex virus type 1 with eczema herpeticum analyzed using restriction fragment length polymorphism of polymerase chain reaction
    Masami Yoshida
    First Department of Dermatology, School of Medicine, Toho University, Omori nishi 5 21 16, Ota ku, Tokyo 143 8540, Japan
    J Virol Methods 109:11-6. 2003
    ..This is the first report of PCR-based approach for classification of HSV-1 strains into genotypes seeking an association of a genotype with clinical manifestation...
  29. ncbi Herpes simplex: autoinoculation versus dissemination
    Batsheva Marcus
    Dermatology Unit Kaplan Medical Center, Rechovot, Israel
    Acta Dermatovenerol Croat 13:237-41. 2005
    ..Four cases of autoinoculation and two of KVE illustrate the differences between these two forms of viral spread...
  30. pmc Junctional adhesion molecule overexpression in Kaposi varicelliform eruption skin lesions - as a possible herpes virus entry site
    Ana Maria Abreu-Velez
    Georgia Dermatopathology Associates, Atlanta, Georgia, USA
    N Am J Med Sci 2:433-7. 2010
    ..The replication of HSV in cultured cells is accompanied by the appearance of surface receptors with an affinity for the Fc region of immunoglobulin G...
  31. ncbi Atypical hand, foot, and mouth disease associated with coxsackievirus A6 infection, Edinburgh, United Kingdom, January to February 2014
    C Sinclair
    Department of Dermatology, Lauriston Building, Edinburgh, United Kingdom
    Euro Surveill 19:20745. 2014
    ....
  32. pmc Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response
    Michiko K Oyoshi
    Division of Immunology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 106:14954-9. 2009
    ..Addition of IL-17 promoted VV replication in skin explants. These results suggest that IL-17 may be a potential therapeutic target in EV...
  33. doi Images in emergency medicine. Eczema herpeticum
    David A Guss
    University of California, San Diego, Department of Emergency Medicine, San Diego, CA, USA
    Ann Emerg Med 52:83, 92. 2008
  34. pmc IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication
    Byung Eui Kim
    Department of Pediatrics, National Jewish Health, Denver, Colorado, USA
    J Invest Dermatol 133:2678-85. 2013
    ..Filaggrin breakdown products, however, inhibited HSV-1 replication in vitro. ..
  35. ncbi Eczema vaccinatum: a reaction to the smallpox vaccine. A report of a rare but potentially lethal consequence
    Mary Jean Babic
    Am J Nurs 107:30-1. 2007
  36. ncbi Pathological role of regulatory T cells in the initiation and maintenance of eczema herpeticum lesions
    Ryo Takahashi
    Division of Flow Cytometry, Kyorin University Graduate School of Medicine, Mitaka, Tokyo 181 8611, Japan
    J Immunol 192:969-78. 2014
    ....
  37. pmc IL-10 suppresses IL-17-mediated dermal inflammation and reduces the systemic burden of Vaccinia virus in a mouse model of eczema vaccinatum
    Alanna R Darling
    Department of Pediatrics, Boston Children s Hospital, Boston, MA 02115, USA
    Clin Immunol 150:153-60. 2014
    ....
  38. ncbi Complications of the smallpox vaccine
    Benjamin Schwartz
    Department of Dermatology, Mount Sinai School of Medicine SE, 98 Street, New York, NY, 10029, USA
    Int J Dermatol 44:289-92. 2005
  39. ncbi Hyperimmunoglobulin E syndrome: two cases and a review of the literature
    Christine A DeWitt
    Division of Dermatology, Southern Illinois University School of Medicine, Springfield, Illinois, USA
    J Am Acad Dermatol 54:855-65. 2006
    ..He has occasional episodes of cold abscesses and sinusitis, but has had excellent control since institution of this regimen and has not experienced any adverse effects...
  40. ncbi Increased susceptibility to cutaneous viral infections in atopic dermatitis: the roles of regulatory T cells and innate immune defects
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Probl Dermatol 41:125-35. 2011
    ..Here we provide several potential explanations for why AD patients are at greater risk for eczema molluscatum...
  41. pmc Three more learning points
    Ignacio Garcia-Doval
    PLoS Med 2:e30. 2005
  42. ncbi A case of atopic dermatitis and erythema multiforme
    J S Rosa
    Department of Pediatrics, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    Eur Ann Allergy Clin Immunol 44:30-1. 2012
    ..To our knowledge, this is the first reported case of a patient with atopic dermatitis presenting with erythema multiforme likely secondary to eczema herpeticum and HSV viremia...
  43. ncbi Kaposi's varicelliform eruption: a case report and review of the literature
    Sasha C Kramer
    Department of Dermatology, Geisinger Medical Center, Danville, Pennsylvania 17822, USA
    Cutis 73:115-22. 2004
    ....
  44. pmc Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization
    Carolyn J Broccardo
    Department of Immunology, National Jewish Health, Denver, Colo 80206, USA
    J Allergy Clin Immunol 127:186-93, 193.e1-11. 2011
    ..Eczema herpeticum is a disseminated herpes simplex virus infection that occurs in a small subset of patients...
  45. ncbi Eczema vaccinatum
    Jennifer L Reed
    Laboratory of Plasma Derivatives, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD 20892, USA
    Clin Infect Dis 54:832-40. 2012
    ..We conclude by considering how its occurrence might be minimized in the event of a return to universal vaccination...
  46. ncbi Topical corticosteroids and hospital length of stay in children with eczema herpeticum
    Paul L Aronson
    Division of Emergency Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Dermatol 30:215-21. 2013
    ....
  47. ncbi Facial rash - a case study
    Kam Cheong Wong
    Prevocational Education and Training, Beyond Medical Education, University of Sydney, New South Wales
    Aust Fam Physician 41:503-4. 2012
    ..He had a past history of eczema but no other significant past medical history and no allergies. He was not taking any regular medications...
  48. ncbi Eczema herpeticum
    Andreas Wollenberg
    Department of Dermatology, Ludwig Maximilian University, Munich, Germany muenchen de
    Chem Immunol Allergy 96:89-95. 2012
    ..This contribution covers eczema herpeticum, the disseminated viral infection of an eczematous skin disease with the herpes simplex virus, as it is the clinically most important viral complication of AD...
  49. ncbi A case of pityriasis rubra pilaris with associated focal acantholytic dyskeratosis complicated by Kaposi's varicelliform eruption
    Gulsun Erdag
    Section of Dermatopathology, Department of Pathology, University of Virginia, Charlottesville, VA, USA
    J Cutan Pathol 38:919-22. 2011
    ..We report a patient with PRP whose biopsies showed both herpes simplex infection and FAD. A complete understanding of the mechanism behind this eruption evolved gradually, aided in great measure by the histopathologic findings...
  50. ncbi Empiric antibiotics and outcomes of children hospitalized with eczema herpeticum
    Paul L Aronson
    Division of Emergency Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Dermatol 30:207-14. 2013
    ..These findings highlight the importance of early recognition of systemic bacterial illness in children with eczema herpeticum. Empiric antibiotics did not affect mortality, which is low...
  51. pmc Delayed acyclovir and outcomes of children hospitalized with eczema herpeticum
    Paul L Aronson
    Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatrics 128:1161-7. 2011
    ..To describe the epidemiology and outcomes of children hospitalized with eczema herpeticum and to determine the association with delayed acyclovir on outcomes...
  52. ncbi Update on systemic therapies for atopic dermatitis
    Kristopher S Denby
    Department of Dermatology, University of Rochester Medical Center, Rochester, New York 14642, USA
    Curr Opin Allergy Clin Immunol 12:421-6. 2012
    ..Familiarity with the latest literature on the benefits and risks of these treatments will enable the clinician and patient to select the most appropriate therapy based on the patient's lifestyle, assessments of risks and comorbidities...
  53. pmc Why is eczema herpeticum unexpectedly rare?
    Donald Y M Leung
    Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    Antiviral Res 98:153-7. 2013
    ..ADEH+ subjects are also more likely to have a history of food allergy or asthma, early onset of AD and a history of other cutaneous infections with Staphylococcus aureus or molluscum contagiosum...
  54. pmc Susceptibility to vaccinia virus infection and spread in mice is determined by age at infection, allergen sensitization and mast cell status
    Joanne Domenico
    Division of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    Int Arch Allergy Immunol 158:196-205. 2012
    ....
  55. pmc Genetic variants in interferon regulatory factor 2 (IRF2) are associated with atopic dermatitis and eczema herpeticum
    Pei Song Gao
    Department of Medicine, Johns Hopkins Asthma and Allergy Center, Johns Hopkins University, Baltimore, Maryland 21224, USA
    J Invest Dermatol 132:650-7. 2012
    ..008). Our findings suggest that distinct markers in IRF2 may be associated with AD and ADEH, which may depend upon ethnic ancestry, and genetic variants in IRF2 may contribute to an abnormal immune response to HSV...
  56. ncbi Innate immunity in atopic dermatitis
    Andreas Wollenberg
    Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Germany
    Clin Rev Allergy Immunol 41:272-81. 2011
    ..Future therapeutic approaches to AD may include enhancement of impaired innate in addition to downregulation of dysfunctional adaptive immunity...
  57. ncbi Kaposi's varicelliform eruption. Absence of ocular involvement
    D P Fivenson
    Department of Dermatology, University of Cincinnati, Ohio College of Medicine
    Arch Dermatol 126:1037-9. 1990
    ..All random conjunctival swab cultures performed in 3 patients were positive for growth of viable HSV. Although ocular exposure to HSV may commonly occur in KVE, ocular pathology due to this virus does not appear to be a common sequela...
  58. ncbi Kaposi's varicelliform eruption in an HIV-positive patient after laser resurfacing
    M Rodriguez-Serna
    Department of Dermatology, Hospital General Universitario, Avd Tres Cruces, S N Valencia 46014, Spain
    J Eur Acad Dermatol Venereol 18:711-2. 2004
    ..This is the first report, to the best of our knowledge, of Kaposi's varicelliform eruption after laser resurfacing. The immunodepressed status of the patient may have played a role in her infection...
  59. ncbi Kaposi's varicelliform eruption in association with rosacea
    Isil Kucukyilmaz
    Department of Dermatology, Akdeniz University School of Medicine, Antalya, Turkey
    J Am Acad Dermatol 51:S169-72. 2004
    ..We report here a new case of Kaposi's varicelliform eruption in a 38-year-old woman with rosacea. To our knowledge, this is the first case of Kaposi's varicelliform eruption associated with rosacea to be reported...
  60. ncbi The clinical spectrum and therapeutic challenge of eczema herpeticum
    Stephanie Frisch
    Department of Pediatrics and Dermatology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, USA
    Pediatr Dermatol 28:46-52. 2011
    ....
  61. pmc Atopic dermo-respiratory syndrome is a correlate of eczema herpeticum
    T Hinz
    Department of Dermatology and Allergy, University of Bonn, Bonn, Germany
    Allergy 66:925-33. 2011
    ..The aim of this work was to identify changes in clinical and laboratory parameters in acute EH patients, before and after 6 weeks of treatment, as well as differences between AD patients with and without a history of EH...
  62. ncbi Kaposi varicelliform eruption in an infant
    Silvano Menni
    Clinica Dermatologica IV, Università degli Studi di Milano Ospedale S Paolo, Milan, Italy
    J Pediatr 146:432. 2005
  63. pmc Specificity protein 1 is pivotal in the skin's antiviral response
    Lianghua Bin
    Department of Pediatrics, National Jewish Health, Denver, Colo, USA
    J Allergy Clin Immunol 127:430-438.e1-2. 2011
    ..Previous studies have found specificity protein (Sp) 1 transcription factor in the viral replication machinery and postulated that Sp1 was required for viral replication in host cells...
  64. ncbi Eczema herpeticum: a case report
    M S Khan
    Department of Paediatric Dentistry, Birmingham Children s Hospital, Birmingham, UK
    Int J Paediatr Dent 15:136-9. 2005
    ..This paper describes one such case, discusses the aetiology, presentation and management of this condition, and highlights the importance of early recognition by the clinician...
  65. pmc Skin inflammation arising from cutaneous regulatory T cell deficiency leads to impaired viral immune responses
    Eva Jasmin Freyschmidt
    Division of Immunology, Department of Medicine, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 185:1295-302. 2010
    ..p.) induced immune responses comparable to controls. Our findings implicate allergic skin inflammation resulting from local Treg deficiency in the pathogenesis of EV...
  66. ncbi Recurrent herpes simplex infection in multiple locations in an otherwise healthy boy
    Peter Komericki
    Department for Environmental Dermatology and Venereology, Medical University of Graz, Graz, Austria
    Pediatr Dermatol 27:113-4. 2010
    ..We confirmed a diagnosis of multifocal herpes simplex infection, and hypothesize that this was a result of his previous eczema herpeticum, an unusual complication, in an otherwise healthy and immunocompetent child...
  67. pmc Vaccinia virus-specific molecular signature in atopic dermatitis skin
    Dmitry N Grigoryev
    Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, USA
    J Allergy Clin Immunol 125:153-159.e28. 2010
    ..However, the precise mechanism or mechanisms and key factor or factors of EV are unknown...
  68. ncbi Psoriasis herpeticum: three cases of Kaposi's varicelliform eruption in psoriasis
    Beth R Santmyire-Rosenberger
    Department of Dermatology, Washington Hospital Center, Washington, DC 20010, USA
    J Am Acad Dermatol 53:52-6. 2005
    ..KVE is most often seen in patients with underlying atopic dermatitis, but has also been seen in association with other papulosquamous and acantholytic disorders. However, eczema herpeticum rarely occurs in patients with psoriasis...
  69. ncbi High frequency of detection of herpes simplex virus DNA in the oral cavity of patients with eczema herpeticum
    Masami Yoshida
    First Department of Dermatology, Toho University School of Medicine, Tokyo, Japan
    Dermatology 209:101-3. 2004
    ..It has been reported that herpes simplex virus (HSV) DNA was detected in the oral cavity of patients with herpes labialis under various conditions such as during oral surgery...
  70. ncbi Photo Quiz. What is your diagnosis? Eczema herpeticum superinfection in a patient with pemphigus vulgaris
    Christine L Mackley
    Department of Dermatology, Milton S Hershey Medical Center, Pennsylvania State College of Medicine, Hershey, USA
    Cutis 73:301, 317-8. 2004
  71. ncbi Images in clinical medicine. Eczema vaccinatum--a timely reminder
    Allon E Moses
    Hadassah University Medical Center, Jerusalem 91120, Israel
    N Engl J Med 346:1287. 2002
  72. ncbi Unilateral Darier's disease complicated by Kaposi's varicelliform eruption limited to the affected skin
    Y Fortuño
    Br J Dermatol 146:1106-7. 2002
  73. ncbi Two unusual cases of Kaposi's varicelliform eruption
    A Saraswat
    Acta Derm Venereol 82:138-9. 2002
  74. ncbi Adults with atopic dermatitis and herpes simplex and topical therapy with tacrolimus: what kind of prevention?
    Jann Lubbe
    Arch Dermatol 139:670-1. 2003
  75. ncbi Eczematous skin disease and recall of past diagnoses: implications for smallpox vaccination
    Allison L Naleway
    Marshfield Clinic Research Foundation, Marshfield, Wisconsin 54449, USA
    Ann Intern Med 139:1-7. 2003
    ..According to current recommendations, a preexposure vaccination program should identify these persons and exclude them from participating...
  76. ncbi [Eczema herpeticum caused by herpes simplex virus type 2. Review of the literature about one case]
    Francisca Schroeder H
    Servicio de Dermatologia y Venereologia, Hospital Barros Luco Trudeau, Santiago, Chile
    Rev Chilena Infectol 26:356-9. 2009
    ....
  77. ncbi Eczema herpeticum localized to area of tinea cruris
    Sung Ho Kang
    Department of Dermatology, Chonbuk National University Medical School, Korea
    J Dermatol 31:60-2. 2004
    ..We experienced a patient with tinea cruris who developed EH within a fungal infection. To our knowledge, dermatophyte infection as an underlying cutaneous disorder for EH has not been previously described in the English literature...
  78. ncbi Images in clinical medicine. Use of multinucleated giant cells to diagnose a viral eruption
    Frank C Koranda
    University of Kansas Medical Center, Kansas City, KS 66160, USA
    N Engl J Med 350:e6. 2004
  79. ncbi Kaposi varicelliform eruption associated with 0.1% tacrolimus ointment treatment in atopic blepharitis
    Minori Miyake-Kashima
    Department of Ophthalmology, Tokyo Dental College, Chiba 272 8513, Japan
    Cornea 23:190-3. 2004
    To report the association of Kaposi varicelliform eruption (KVE) with 0.1% tacrolimus ointment treatment of atopic blepharitis in a patient with atopic dermatitis (AD).
  80. ncbi [A case of rhabdomyolysis associated with Kaposi's varicelliform eruption]
    Masahiro Takaki
    Institute of Tropical Medicine, Department of Internal Medicine, Nagasaki University
    Kansenshogaku Zasshi 78:59-63. 2004
    ..It was localized in the iliopsoas muscles. Since severe rhabdomyolysis may induce fatal acute renal failure, it is important to recognize that rhabdomyolysis can complicate Herpes simplex virus infection...
  81. ncbi [Eczema herpeticatum]
    S Wetzel
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München, Munchen
    Hautarzt 55:646-52. 2004
    ..While intravenous acyclovir is still regarded as standard treatment of eczema herpeticum, several recently-developed antiviral drugs provide therapeutic options...
  82. ncbi Angiogenic cytokines in serum and cutaneous lesions of patients with polyarteritis nodosa
    Kanako Kikuchi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Am Acad Dermatol 53:57-61. 2005
    ....
  83. pmc Eczema herpeticum and clinical criteria for investigating smallpox
    David A Boyd
    Department of Dermatology, Naval Hospital Jacksonville, Jacksonville, Florida 32214, USA
    Emerg Infect Dis 15:1102-4. 2009
    ..The Tzanck preparation was critical for rapid diagnosis of herpetic infection and exclusion of smallpox...
  84. ncbi Acute skin conditions in children
    C Rosalind Gait
    Department of Dermatology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester LE1 5WW
    Br J Hosp Med (Lond) 69:M56-8. 2008
  85. ncbi Kaposi's varicelliform eruption complicating allergic contact dermatitis
    Andrea Paradisi
    J Am Acad Dermatol 54:732-3. 2006
  86. doi Eczema and infection
    Patricia A Treadwell
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA
    Pediatr Infect Dis J 27:551-2. 2008
  87. ncbi Risk factors of atopic dermatitis patients for eczema herpeticum
    Wenming M Peng
    J Invest Dermatol 127:1261-3. 2007
  88. ncbi Severe eczema vaccinatum in a household contact of a smallpox vaccinee
    Surabhi Vora
    Section of Infectious Diseases, University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Clin Infect Dis 46:1555-61. 2008
    ..The father had a history of inactive eczema but reportedly reacted normally to the vaccine. The child's mother also developed contact vaccinia infection...
  89. doi Adverse event related to smallpox vaccination
    Nellie Bristol
    Disaster Med Public Health Prep 1:11-2. 2007
  90. ncbi Smallpox vaccine. A tame virus runs amok
    Jocelyn Kaiser
    Science 316:1418-9. 2007
  91. ncbi Vesiculopapular rash
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Infect Dis 43:1308, 1368-9. 2006
  92. ncbi [Vesicular lesions localized to eyelids]
    M Feito Rodríguez
    Servicio de Dermatologia, Hospital Universitario La Paz, Madrid, Espana
    An Pediatr (Barc) 67:183-4. 2007
  93. ncbi Autoinoculation and dissemination are two different forms of herpes virus spread
    Ronni Wolf
    Dermatology Unit Kaplan Medical Center, 76100 Rechovot, Israel
    Acta Dermatovenerol Croat 14:258-60. 2006
    ..Presented are typical examples of the two forms of viral spread...
  94. ncbi Kaposi's varicelliform eruption associated with the use of tacrolimus ointment in two neonates
    Hajime Kimata
    Indian J Dermatol Venereol Leprol 74:262-3. 2008
  95. ncbi Eczema herpeticum: making the diagnosis in the emergency department
    James S Studdiford
    Department of Family and Community Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    J Emerg Med 40:167-9. 2011
    ..Recognition of EH in the acute care setting is essential for the provision of timely and specific treatment and to avoid the serious sequelae of this condition...
  96. ncbi Eczema herpeticum in a patient with atopicdermatitis treated with topical tacrolimus
    A Khalid
    Ir Med J 98:220-1. 2005
  97. ncbi [Eruptive spread of erosive skin lesions in a 33-year old patient]
    Mirjana Ziemer
    Klinik für Dermatologie und dermatologische Allergologie der Friedrich Schiller Universität Jena
    J Dtsch Dermatol Ges 2:459-61. 2004
  98. ncbi Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: an investigation of potential fomites in the home environment
    Edith Lederman
    Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Vaccine 27:375-7. 2009
    ..Both siblings were found to have serologic evidence of orthopoxvirus exposure. These findings have implications for smallpox preparedness, especially in situations where some household members are not candidates for vaccination...
  99. ncbi Analysis of herpes simplex virus type 1 restriction fragment length polymorphism variants associated with herpes gladiatorum and Kaposi's varicelliform eruption in sumo wrestlers
    Fumihiko Ban
    Herpesvirus Laboratory, Department of Virology I, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    J Gen Virol 89:2410-5. 2008
    ..These data indicated that reactivation and transmission of latent HSV-1 infections, especially BgK(L), occurred frequently among wrestlers and was caused by severe skin damage. These results support the BgK(L) dispersion hypothesis...
  100. ncbi Fatal outcome due to bacterial superinfection of eczema herpeticum in a patient with mycosis fungoides
    Susana Mallo-Garcia
    Dermatol Online J 14:21. 2008
    b>Kaposi varicelliform eruption or eczema herpeticum is well known to be associated with several chronic dermatoses, including atopic dermatitis, foliaceus pemphigus, seborrheic dermatitis, Darier disease, and congenital ichthyosiform ..
  101. ncbi Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream
    Sonia Segura
    Acta Derm Venereol 85:524-5. 2005

Research Grants2

  1. Tec inhibitors- A new therapeutic for allergic diseases
    Yuko Kawakami; Fiscal Year: 2003
    ..Since we have a screening method for searching for Tec inhibitors whose usefulness has been proven, we will also expand our search for better compounds. ..
  2. MECHANISMS OF CHEMOKINE-INDUCED INFLAMMATION IN HUMANS
    Lisa Beck; Fiscal Year: 2005
    ..Results of these studies are likely to provide insights into the mechanisms by which chemokines induce cutaneous cell recruitment and will likely identify entirely new biological effects of C-C chemokines. ..