erythema infectiosum

Summary

Summary: Contagious infection with human B19 Parvovirus most commonly seen in school age children and characterized by fever, headache, and rashes of the face, trunk, and extremities. It is often confused with rubella.

Top Publications

  1. ncbi Parvovirus B19
    Neal S Young
    Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, MD 20892 1652, USA
    N Engl J Med 350:586-97. 2004
  2. ncbi Human parvovirus B19 infection and autoimmunity
    Claudio Lunardi
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Autoimmun Rev 8:116-20. 2008
  3. ncbi [Optic neuropathy after erythema infectiosum]
    H Wilhelm
    Abt für Pathophysiologie des Sehens und Neuroophthalmologie, Universitäts Augenklinik Tübingen
    Klin Monbl Augenheilkd 213:355-7. 1998
  4. ncbi Detection of parvovirus B19 in a case of erythema infectiosum with myositis
    Janak Kishore
    Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226 014, India
    Indian Pediatr 43:814-7. 2006
  5. pmc Analysis of nucleotide sequences of human parvovirus B19 genome reveals two different modes of evolution, a gradual alteration and a sudden replacement: a retrospective study in Sapporo, Japan, from 1980 to 2008
    Masashi Suzuki
    Department of Pediatrics, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo 060 8543, Japan
    J Virol 83:10975-80. 2009
  6. ncbi Human parvovirus B19: relevance in internal medicine
    A M van Elsacker-Niele
    Department of Medical Microbiology, Public Health Laboratory, Leeuwarden, The Netherlands
    Neth J Med 54:221-30. 1999
  7. ncbi [Scapula alata as a complication of infection with human parvovirus B19 (erythema infectiosum)]
    D Zander
    Klinik und Poliklinik für Orthopädie, Rheinischen Friedrich Wilhelms Universität Bonn
    Z Orthop Ihre Grenzgeb 139:174-6. 2001
  8. ncbi [The use of real-time polymerase chain reaction and enzyme immunoassay for the diagnosis of acute parvovirus B19 infections in immunosuppressed patients]
    Nilgun Isik
    Istanbul Universitesi Istanbul Tip Fakultesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Capa, Istanbul
    Mikrobiyol Bul 37:277-83. 2003
  9. ncbi A pilot study on the seroprevalence of parvovirus B19 infection
    Mary Abraham
    Department of Clinical Virology, Christian Medical College and Hospital, Vellore, India
    Indian J Med Res 115:139-43. 2002
  10. ncbi [Parvovirus B19: importance of diathesis in the clinical expression of a common infection]
    David Germanaud
    Service de pédiatrie générale et médecine interne pédiatrique, Hopital Necker Enfants Malades, 75743 Paris Cedex 15
    Rev Prat 57:1049-55. 2007

Research Grants

  1. SURROGATE ASSAY FOR B19 PARVOVIRUS SERUM NEUTRALIZATION
    GEETHA BANSAL; Fiscal Year: 1990
  2. HUMAN PARVOVIRUS B19
    Arun Srivastava; Fiscal Year: 1992
  3. INTERNATIONAL CONFERENCE--PARVOVIRUS
    KENNETH BERNS; Fiscal Year: 1993
  4. Short Tandem Repeat Polymorphisms in Cytomegalovirus
    James Bale; Fiscal Year: 2003
  5. PULMONARY COMPLICATIONS IN PEDIATRIC SICKLE CELL DISEASE
    Kim Smith Whitley; Fiscal Year: 2002

Detail Information

Publications195 found, 100 shown here

  1. ncbi Parvovirus B19
    Neal S Young
    Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, MD 20892 1652, USA
    N Engl J Med 350:586-97. 2004
  2. ncbi Human parvovirus B19 infection and autoimmunity
    Claudio Lunardi
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Autoimmun Rev 8:116-20. 2008
    Human parvovirus B19 infection is responsible for a wide range of human diseases ranging from mild erythema infectiosum in immunocompetent children to fetal loss in primary infected pregnant women and aplastic anemia or lethal cytopenias ..
  3. ncbi [Optic neuropathy after erythema infectiosum]
    H Wilhelm
    Abt für Pathophysiologie des Sehens und Neuroophthalmologie, Universitäts Augenklinik Tübingen
    Klin Monbl Augenheilkd 213:355-7. 1998
    ..Optic neuropathies can not always easily be classified as neuritis or ischemic disease...
  4. ncbi Detection of parvovirus B19 in a case of erythema infectiosum with myositis
    Janak Kishore
    Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226 014, India
    Indian Pediatr 43:814-7. 2006
    A well documented case of erythema infectiosum is being reported here for the first time from India which was associated with myositis that has not been reported globally...
  5. pmc Analysis of nucleotide sequences of human parvovirus B19 genome reveals two different modes of evolution, a gradual alteration and a sudden replacement: a retrospective study in Sapporo, Japan, from 1980 to 2008
    Masashi Suzuki
    Department of Pediatrics, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo 060 8543, Japan
    J Virol 83:10975-80. 2009
    ..In that period, six outbreaks of erythema infectiosum occurred regularly at 5-year intervals...
  6. ncbi Human parvovirus B19: relevance in internal medicine
    A M van Elsacker-Niele
    Department of Medical Microbiology, Public Health Laboratory, Leeuwarden, The Netherlands
    Neth J Med 54:221-30. 1999
    ..individuals have serologic evidence of a past infection, which may present as the common childhood disease erythema infectiosum. At the age of 70, seroprevalence reaches 80 to 100%...
  7. ncbi [Scapula alata as a complication of infection with human parvovirus B19 (erythema infectiosum)]
    D Zander
    Klinik und Poliklinik für Orthopädie, Rheinischen Friedrich Wilhelms Universität Bonn
    Z Orthop Ihre Grenzgeb 139:174-6. 2001
    This article reports a case of a 38-year-old woman suffering from erythema infectiosum (slap-cheek disease) complicated by arthritis and severe brachial plexus neuritis resulting in scapula winging.
  8. ncbi [The use of real-time polymerase chain reaction and enzyme immunoassay for the diagnosis of acute parvovirus B19 infections in immunosuppressed patients]
    Nilgun Isik
    Istanbul Universitesi Istanbul Tip Fakultesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Capa, Istanbul
    Mikrobiyol Bul 37:277-83. 2003
    ..in patients with hemolytic anemia, thrombocytopenia, neutropenia and transient arthritis accompanied with erythema infectiosum, especially in immunosuppressed patients...
  9. ncbi A pilot study on the seroprevalence of parvovirus B19 infection
    Mary Abraham
    Department of Clinical Virology, Christian Medical College and Hospital, Vellore, India
    Indian J Med Res 115:139-43. 2002
    Human parvovirus B 19 (PVB 19) causes aplastic crisis in children with congenital haemolytic anaemia, erythema infectiosum, abortion and stillbirth...
  10. ncbi [Parvovirus B19: importance of diathesis in the clinical expression of a common infection]
    David Germanaud
    Service de pédiatrie générale et médecine interne pédiatrique, Hopital Necker Enfants Malades, 75743 Paris Cedex 15
    Rev Prat 57:1049-55. 2007
    ..The importance of age, hematopoietic and immune status has been raised and besides, effective diagnostic assays, treatments and possibly vaccine have been developed that can be rationally used at the light of this knowledge...
  11. ncbi Current molecular epidemiology and human parvovirus B19 infection
    Kenichi Umene
    Department of Virology, Faculty of Medicine Kyushu University, Fukuoka 812 8582, Japan
    Pathol Biol (Paris) 50:285-94. 2002
    ..Human parvovirus B19 is a common human pathogen associated with a wide variety of diseases, including erythema infectiosum, aplastic crisis, hydrops fetalis, and arthritis...
  12. ncbi Prevalence and quantitation of parvovirus B19 DNA levels in blood donors with a sensitive polymerase chain reaction screening assay
    Steven H Kleinman
    Westat, 1650 Research Boulevard, Rockville, MD 20850, USA
    Transfusion 47:1756-64. 2007
    ..Blood donor parvovirus B19 DNA prevalence with sensitive nucleic acid test assays has recently been demonstrated to be higher than that found with assays designed to detect high viral titers in the plasma manufacturing sector...
  13. ncbi A clinical study of adult human parvovirus B19 infection
    Hitoshi Hayakawa
    Department of Internal Medicine, Kagoshima City Hospital
    Intern Med 41:295-9. 2002
    ..We investigated the clinical aspects of adult human parvovirus (HPV) B19 infection...
  14. pmc Acute respiratory distress syndrome in a child with human parvovirus B19 infection
    Claudia Ferraz
    Department of Pediatrics, Pedro Hispano Hospital, Rua Dr Eduardo Torres, 4454 509 Matosinhos, Portugal
    Pediatr Infect Dis J 24:1009-10. 2005
    ..It seems likely, but it was not proved, that the parvovirus infection caused acute respiratory distress syndrome...
  15. ncbi [Parvovirus B 19 infection during pregnancy]
    I Mylonas
    Frauenklinik München Klinikum Innenstadt, Ludwig Maximilians Universitat, Munchen, Germany
    Z Geburtshilfe Neonatol 211:60-8. 2007
    ..The virus causes in children the erythema infectiosum (German measles)...
  16. ncbi Parvovirus B19 in pregnancy
    Meredith Goff
    Midwifery Education Program, Yale University School of Nursing, USA
    J Midwifery Womens Health 50:536-8. 2005
    ..Parvovirus B19, the causative agent of fifth disease, is one of the more serious of the common viruses. Understanding the pathophysiology and appropriate testing for parvovirus will help providers better counsel their patients...
  17. ncbi Clinical problem-solving. No respecter of age--a previously healthy 65-year-old woman went to her primary care physician in late August, seeking evaluation of a "spot" that had appeared on her right leg 3 weeks earlier
    Don R Martin
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 357:1856-9. 2007
  18. ncbi Generalized petechial eruption induced by parvovirus B19 infection
    Mike McNeely
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Acad Dermatol 52:S109-13. 2005
    Parvovirus infection classically causes erythema infectiosum. During the past 2 decades, other unusual skin eruptions have been noted in association with parvovirus infection...
  19. ncbi Relevance of specific immunoglobulin M and immunoglobulin G for parvovirus B19 diagnosis in patients with acute lymphoblastic leukemia receiving chemotherapy: prospective study
    Maysaa el-Sayed Zaki
    Department of Pathology, Mansoura University, Mansoura, Egypt
    Arch Pathol Lab Med 131:1697-9. 2007
    ..Immunocompromised patients suffer from prolonged viral infections often without detectable immune response. However, even if the immune response occurs, can it clear the virus completely?..
  20. ncbi [Acute transitory intrafamilial erythroblastopenia and hereditary spherocytosis: role of parvovirus B19]
    B Granel
    , , 264, rue Saint-Pierre, 13385 Marseille, France
    Rev Med Interne 22:664-7. 2001
    ..CONCLUSION: Our observation is a reminder that the contagiosity of parvovirus B19 is high in household contacts and that protection of family members should rapidly be considered in hereditary spherocytosis...
  21. ncbi Acute parvovirus B19 infection during anti-retroviral therapy
    H Taguchi
    Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
    J Infect Chemother 7:110-2. 2001
    ..More than likely, highly active anti-retroviral therapy (HAART), including a protease inhibitor, played a role in clearing the virus...
  22. ncbi Anti-VP1 and anti-VP2 antibodies detected by immunofluorescence assays in patients with acute human parvovirus B19 infection
    R F Pereira
    Departamento de Microbiologia e Parasitologia, , UFF, , RJ, Brasil
    Mem Inst Oswaldo Cruz 96:507-13. 2001
    ..We used 80 sera collected from 58 erythema infectiosum and 6 transient aplastic crisis patients to test IgM and IgG antibodies against these two proteins in an ..
  23. ncbi [Parvovirus B19 outbreak in a rural community in Alicante]
    Francisco Martínez-Campillo
    Sección de Epidemiologia Centro Salud Pública de Alicante España
    Enferm Infecc Microbiol Clin 20:376-9. 2002
    Parvovirus B19 (PVB19) has been identified as the cause of erythema infectiosum. The epidemiology of PVB19 has not been extensively studied in Spain or in the autonomic community of Valencia...
  24. ncbi Parvovirus B19 infection--an emerging infectious disease?
    Galia Rahav
    Isr Med Assoc J 4:810-1. 2002
  25. pmc Quantification of parvovirus B19 DNA using COBAS AmpliPrep automated sample preparation and LightCycler real-time PCR
    Stefan Schorling
    Roche Diagnostics GmbH, Penzberg, Germany
    J Mol Diagn 6:37-41. 2004
    ....
  26. ncbi Intrauterine parvovirus B19 infection: early prenatal diagnosis is possible
    Michele Trotta
    Int J Infect Dis 8:130-1. 2004
  27. ncbi [Progresses in diagnosis and treatment of intrauterine infection with cytomegalovirus and human parvovirus B19]
    Wan fang Wu
    Zhonghua Er Ke Za Zhi 41:902-5. 2003
  28. ncbi [A 35-year-old man with fever and purpuric exanthema]
    Manuel López-Gómez
    Servicio de Medicina Interna, Hospital Universitario Virgen de las Nieves, Pta José Fernández Martínez, ptal 7, 3oB, 18015 Granada, Spain
    Enferm Infecc Microbiol Clin 24:277-9. 2006
  29. ncbi Epidemiology of human parvovirus B19 in children with sickle cell disease
    Kim Smith-Whitley
    Division of Hematology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
    Blood 103:422-7. 2004
    ....
  30. ncbi Sensitive and rapid diagnosis of human parvovirus B19 infection by loop-mediated isothermal amplification
    Y Yamada
    First Department of Dermatology, School of Medicine, and Sakura Hospital, Toho University, Tokyo, Japan
    Br J Dermatol 155:50-5. 2006
    ..The virological diagnosis of B19 infection is usually based on time-consuming serological tests and polymerase chain reaction (PCR)...
  31. ncbi Prolonged parvovirus b19 viremia in spite of neutralizing antibodies after erythema infectiosum in pregnancy
    Marinko Dobec
    Medica, Medizinische Laboratorien Dr F Kaeppeli, Zurich, Switzerland
    Gynecol Obstet Invest 63:53-4. 2007
    To check the clearance of parvovirus B19 in the course of the development of neutralizing antibodies after Erythema infectiosum in pregnancy.
  32. ncbi Evaluation of a new LightCycler reverse transcription-polymerase chain reaction infectivity assay for detection of human parvovirus B19 in dry-heat inactivation studies
    Grigori G Prikhod'ko
    Plasma Derivatives Department, Jerome H Holland Laboratory for the Biomedical Sciences, American Red Cross, Rockville, Maryland 20855, USA
    Transfusion 45:1011-9. 2005
    ..B19 (B19) is a widely distributed infectious agent, which causes a variety of illnesses including erythema infectiosum (fifth disease) especially in children, arthritis, aplastic crisis, and hydrops fetalis...
  33. ncbi Papular-purpuric "gloves and socks" syndrome in a mother and daughter
    Abdullah Alfadley
    Department of Medicine, King Faisal Specialist Hospital, Saudi Arabia
    J Am Acad Dermatol 48:941-4. 2003
    ..Additional clinical findings of cutaneous vesicles, bullae, and conjunctivitis are reported in the mother's case. To our knowledge, these are the first 2 cases of PPGSS in a household setting...
  34. ncbi Concurrent detection of human herpesvirus type 6 and measles-specific IgMs during acute exanthematic human parvovirus B19 infection
    David Navalpotro
    Department of Microbiology, University Clinic Hospital, Valencia, Spain
    J Med Virol 78:1449-51. 2006
    ..The study stresses the importance of avidity and PCR tests to obtain a firm diagnosis of febrile exanthematic viral diseases...
  35. ncbi Oral manifestations of papular-purpuric 'gloves and socks' syndrome due to parvovirus B19 infection: the first case presented in Greece and review of the literature
    A Sklavounou-Andrikopoulou
    Department of Oral Pathology and Medicine, School of Dentistry, University of Athens, Greece
    Oral Dis 10:118-22. 2004
    ..Clinical and laboratory evaluation including serologic tests and PCR, confirmed the presence of parvovirus B19. Review of the existing literature on this novel syndrome and its association with parvovirus B19 is also presented...
  36. ncbi Advances in the biology, diagnosis and host-pathogen interactions of parvovirus B19
    Amanda Corcoran
    National Institute for Cellular Biotechnology, Department of Biology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
    J Med Microbiol 53:459-75. 2004
    ....
  37. ncbi [Human parvovirus B19 infection which first presented with petechial hemorrhage, followed by papular-purpuric gloves and socks syndrome and erythema infectiosum]
    Atsuo Sato
    Department of Pediatrics, Yokohama Sakae Kyosai Hospital
    Kansenshogaku Zasshi 76:963-6. 2002
    ..She was very unique as she subsequently exhibited papular-purpuric gloves and socks syndrome and erythema infectiosum during follow-up...
  38. ncbi Childhood viral exanthems
    Jonathan A Dyer
    Department of Dermatology, University of Missorui, Columbia, MO, USA
    Pediatr Ann 36:21-9. 2007
    ..Recognition of the exanthems associated with these infections and the broader clinical scenarios in which they occur can lead to more rapid diagnosis and appropriate treatment for affected patients...
  39. ncbi [Parvovirus B19 infection--a risk factor during pregnancy. Asymptomatic course of disease makes the prevention and treatment more difficult]
    Kristina Broliden
    Kliniskt virologiska laboratoriet, Huddinge Universitetssjukhus
    Lakartidningen 100:222-4. 2003
  40. ncbi Two family members with a syndrome of headache and rash caused by human parvovirus B19
    A C Pereira
    Department of Infectious Diseases, Antonio Pedro University Hospital, University Federal Fluminense, , RJ, Brazil
    Braz J Infect Dis 5:37-9. 2001
    Human parvovirus B19 infection can cause erythema infectiosum (EI) and several other clinical presentations...
  41. ncbi Seroprevalence of varicella zoster virus, parvovirus B19 and Toxoplasma gondii in a Melbourne obstetric population: implications for management
    H Karunajeewa
    Victorian Infectious Diseases Reference Laboratory, North Melbourne, Australia
    Aust N Z J Obstet Gynaecol 41:23-8. 2001
    ....
  42. ncbi Fatal parvovirus myocarditis in a 5-year-old girl
    C E Murry
    Department of Pathology, University of Washington, Seattle, WA 98195, USA
    Hum Pathol 32:342-5. 2001
    ..of a 5-year-old girl who died suddenly, 2 weeks after the clinical diagnosis of a parvoviral infection (erythema infectiosum)...
  43. ncbi [The frequency of human parvovirus B19 infections in Vojvodina]
    Vesna Milosevic
    Institut zajavno zdravlje Vojvodine
    Med Pregl 60:575-9. 2007
    Human parvovirus B19 is found worldwide. It causes various infections, including fifth disease (erythema infectiosum) in small children, acute arthropathy in adults, transient aplastic crisis and chronic anemia in immunocompromised ..
  44. ncbi [Eight cases of human parvovirus B19 arthropathy]
    Yoshito Yoshidome
    Department of Neurology, Imakiire General Hospital, Kagoshima
    Nihon Naika Gakkai Zasshi 93:377-9. 2004
  45. ncbi [Studies on the relationship between anaphylactoid purpura and human parvovirus B19]
    Y Minohara
    Department of Pediatrics, St. Marianna University School of Medicine, Kawasaki
    Kansenshogaku Zasshi 69:928-33. 1995
    ..In this study, five of the sixteen patients had evidence of recent B19 infection by the existence of antibodies and PCR method. In conclusion, it is necessary to investigate the B19 infection with or without EI in the cases of SHP...
  46. pmc Parvovirus B19 infection in Tunisian patients with sickle-cell anemia and acute erythroblastopenia
    Faouzi Regaya
    Viral and Molecular Tumor Diagnostics Unit, Habib Thameur Hospital, 1008 Tunis, Tunisia
    BMC Infect Dis 7:123. 2007
    Human parvovirus B19 is the etiologic agent of erythema infectiosum in children. It is also associated with other clinical manifestations in different target groups...
  47. ncbi Severe anemia from parvovirus b19 infection in pediatric renal transplant recipients: two case reports
    V Pinto
    Exequiel Gonzalez Cortes Hospital, Metropolitan Southern Health Service, Pediatric Department, University of Chile School of Medicine, Santiago, Chile
    Transplant Proc 40:3261-4. 2008
    Human parvovirus B19 (PVB19) is the etiologic agent of erythema infectiosum (fifth disease), a common childhood exanthema. Immunocompromised patients risk developing chronic infections leading to pure red blood cell aplasia...
  48. pmc Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors
    Zhihong Wan
    Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland 20892 1652, USA
    J Clin Invest 120:3530-44. 2010
    ..It causes a wide spectrum of human diseases, including fifth disease (erythema infectiosum) in children and pure red cell aplasia in immunocompromised patients...
  49. ncbi [Infection with parvovirus B19: typical course of erythema infectiosum and its complications]
    H Kirchesch
    Universitäts Hautklinik Köln
    Z Hautkr 65:1007-10. 1990
    ..e. the causative agent of erythema infectiosum. 80% of the patients infected with B19 develop clinical symptoms and typically show the picture of erythema ..
  50. ncbi Human parvovirus B19 infection among patients with chronic blood disorders
    Mona A Badr
    Virology Unit, Department of Pathology Microbiology, King Saud University, College of Medicine, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 23:295-7. 2002
    In a normal host, parvovirus infection can be asymptomatic or can result in erythema infectiosum or arthropathy...
  51. ncbi Human parvovirus B19 infection among hospital staff members after contact with infected patients
    L M Bell
    Children s Hospital of Philadelphia, Division of Infectious Diseases, PA 19104
    N Engl J Med 321:485-91. 1989
    In the spring and summer of 1988, two separate outbreaks of an illness with a rash resembling erythema infectiosum occurred among members of the nursing staff of the Children's Hospital of Philadelphia...
  52. pmc Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals
    Erik D Heegaard
    Department of Clinical Microbiology, University State Hospital, Rigshospitalet, Denmark
    J Clin Microbiol 40:933-6. 2002
    ..referred to as B19) exhibits a marked tropism to human bone marrow (BM), and infection may lead to erythema infectiosum, arthropathy, hydrops fetalis, and various hematologic disorders...
  53. pmc High prevalence of human parvovirus B19 DNA in myocardial autopsy samples from subjects without myocarditis or dilative cardiomyopathy
    Thomas Schenk
    Department of Virology, University Medical Center, Freiburg, Hermann Herder Str 11, 79104 Freiburg, Germany
    J Clin Microbiol 47:106-10. 2009
    Human parvovirus B19 has been linked to a variety of cardiac diseases, as well as to erythema infectiosum, acute arthropathy, and fetal hydrops...
  54. ncbi Chronic human parvovirus B19 infection in rheumatic disease of childhood and adolescence
    Hartwig W Lehmann
    Department of Paediatric Rheumatology, Rheumaklinik Bad Bramstedt, Postfach 14 48, 24572 Bad Bramstedt, Germany
    J Clin Virol 25:135-43. 2002
    Parvovirus B19 causes erythema infectiosum in children, but the virus is associated with an increasing range of different diseases...
  55. ncbi Renal involvement induced by human parvovirus B19 infection
    S Takeda
    Department of Internal Medicine, Kurobe City Hospital, Kurobe, Japan
    Nephron 89:280-5. 2001
    ..B19 (HPB19) infection, we investigated 6 adult patients with transient urinary abnormalities followed by erythema infectiosum. All patients had HPB19-specific IgM antibody and showed mild proteinuria of 0.2-1...
  56. ncbi Different patterns of disease manifestations of parvovirus B19-associated reactive juvenile arthritis and the induction of antiphospholipid-antibodies
    Hartwig W Lehmann
    Department of Pediatrics, University of Giessen, Giessen, Germany
    Clin Rheumatol 27:333-8. 2008
    ..In two patients, erythema infectiosum preceded the development of arthritis and B19 viremia persisted...
  57. ncbi Human parvovirus B19: historical and clinical review
    J Thurn
    Department of Internal Medicine, St Paul Ramsey Medical Center, Minnesota 55101
    Rev Infect Dis 10:1005-11. 1988
    ..Human parvovirus infection has since been associated with arthritis, erythema infectiosum (fifth disease), fetal death, and hydrops fetalis...
  58. ncbi Parvovirus b19 DNA is commonly harboured in human skin
    F Bonvicini
    Division of Microbiology, University of Bologna, Bologna, Italy
    Dermatology 220:138-42. 2010
    Parvovirus B19 is the aetiological agent of erythema infectiosum. The presence of B19 DNA in lesional skin of other cutaneous manifestations has frequently been reported although there is disagreement on the role of the B19 virus in ..
  59. ncbi Human parvovirus infections
    M J Anderson
    University College and Middlesex School of Medicine, London, U K
    J Virol Methods 17:175-81. 1987
    ..More recently, erythema infectiosum, an illness sharing many of the clinical features of rubella, has been found to be the common result of B19 ..
  60. ncbi Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya
    Elfatah Elnifro
    Department of Medical Microbiology, Medical School, University of Al Marghib, Al Kums, Libya
    J Infect Dev Ctries 3:218-20. 2009
    Human parvovirus B19 has been implicated as a primary etiologic agent of erythema infectiosum (fifth disease) and aplastic crisis in patients with chronic haemolytic anemias...
  61. pmc Bioportfolio: lifelong persistence of variant and prototypic erythrovirus DNA genomes in human tissue
    Päivi Norja
    Department of Virology, Haartman Institute, University of Helsinki, FI 00290, Helsinki, Finland
    Proc Natl Acad Sci U S A 103:7450-3. 2006
    Human erythrovirus is a minute, single-stranded DNA virus causing many diseases, including erythema infectiosum, arthropathy, and fetal death. After primary infection, the viral genomes persist in solid tissues...
  62. ncbi Parvovirus B19 and autoimmune diseases
    Olivier Meyer
    Rheumatology Department, Hopital Bichat, 46, rue Henri Huchard, 75018 Paris, France
    Joint Bone Spine 70:6-11. 2003
    Parvovirus B19 (B19) causes many clinical disorders, of which the most common are erythema infectiosum, aplastic crisis complicating chronic hemolytic anemia, and hydrops fetalis...
  63. ncbi Parvovirus B19 and immune disorders
    Agostino Pugliese
    Department of Medical and Surgical Sciences, Clinical Microbiology University of Turin, Amedeo di Savoia Hospital, Turin, Italy
    Cell Biochem Funct 25:639-41. 2007
    Parvovirus B19 (PVB19) is the causative agent of erythema infectiosum and sometimes the infection is correlated with severe haematological complications, or in pregnancy to fetalis hydrops...
  64. ncbi [Systemic manifestations of Parvovirus B19 infections]
    P Seve
    Service de Medecine Interne, Hotel Dieu, 1 Place de l Hopital, 69288 Lyon Cedex 02, France
    Rev Med Interne 25:740-51. 2004
    Parvovirus B19 (B19) causes many clinical disorders, of which the most common are erythema infectiosum, aplastic crisis complicating chronic hemolytic anemia, and hydrops fetalis...
  65. ncbi [Parvovirus B19 infection: not confined to exanthema of erythema infectiosum]
    T F Schwarz
    Max von Pettenkofer Institut fur Hygiene und Medizinische Mikrobiologie, Ludwig Maximilians Universitat Munchen
    Hautarzt 40:1-3. 1989
    The well-known condition of erythema infectiosum is caused by parvovirus B19, a single-stranded DNA virus discovered in 1975. The characteristic erythema obviously does not always appear: antibodies are present in 50%-60% of all adults...
  66. ncbi Risk of adverse outcomes of pregnancy after human parvovirus B19 infection
    J S Kinney
    Respiratory and Enterovirus Branch, Centers for Disease Control, Atlanta, Georgia 30333
    J Infect Dis 157:663-7. 1988
    ..In a second case-control study of women who had stillbirths after outbreaks of erythema infectiosum in area schools, none of the 20 patients or 26 controls were IgM positive at the time of delivery...
  67. ncbi [Association of non-immunologically-induced hydrops fetalis with Parvovirus B19 infection]
    T F Schwarz
    Max von Pettenkofer Institut fur Hygiene und Medizinische Mikrobiologie, Ludwig Maximilians Universitat Munchen
    Geburtshilfe Frauenheilkd 47:572-3. 1987
    Five weeks after the onset of clinical symptoms of erythema infectiosum, a 24 year old pregnant woman, gravida I, para 0, suffered a hydrops fetalis which resulted in fetal loss...
  68. ncbi [Exanthema as a main symptom in the febrile child]
    C Aebi
    Päidiatrische Infektiologie, Universitatsspital Bern, Inselspital, Bern
    Ther Umsch 62:549-55. 2005
    ..g., familial mediterranean fever). Finally, various specific measures need to be taken in reportable diseases, erythema infectiosum (parvovirus B19), primary HIV infection and in Henoch-Schölein purpura.
  69. pmc Evaluation of a synthetic-peptide enzyme-linked immunosorbent assay for immunoglobulin M to human parvovirus B19
    E Fridell
    Department of Virology, Karolinska Institute, Stockholm, Sweden
    J Clin Microbiol 29:1376-81. 1991
    ..Antibodies of the immunoglobulin (Ig) M class were measured in serum samples from patients with erythema infectiosum and controls...
  70. ncbi Refractory status epilepticus owing to human parvovirus B19 encephalitis in a child
    Ilknur Erol
    Department of Pediatrics, Neurology Division, Baskent University School of Medicine, 6 Cadde 72 3 Bahcelievler, 06490 Ankara, Turkey
    J Child Neurol 21:820-2. 2006
    Human parvovirus B19 is the agent that causes erythema infectiosum (fifth disease), a disease that is generally benign and self-limiting. This virus also is associated with severe disease in hemolytic or immunocompromised patients...
  71. ncbi Severe ataxia as a complication of human parvovirus B19 acute encephalitis in a child
    Filippo Greco
    Department of Pediatrics, University of Catania, Catania, Italy
    J Child Neurol 23:1078-80. 2008
    Human parvovirus B19 generally causes erythema infectiosum in childhood, but it can be associated with unusual findings, particularly in immunocompromised patients...
  72. ncbi [Seroprevalence of human parvovirus B 19 antibodies (Sticker's disease/erythema infectiosum) in the DRG population]
    S Wiersbitzky
    Klinik für Kindermedizin, Ernst Moritz Arndt Universitat Greifswald
    Kinderarztl Prax 58:185-9. 1990
    ..Hence it follows that 35-45% of all G.D.R. females of reproductive age are susceptible to a parvovirus B19 infection...
  73. ncbi Gloves and socks syndrome associated with parvovirus B19 infection
    Anita Hryncewicz-Gwozdz
    Anita Hryncewicz Gwozdz, MD, ul Chałubińskiego 1, Wrocław 50 368, Poland
    Acta Dermatovenerol Croat 14:163-6. 2006
    ..Parvovirus B19 plays a role in the pathomechanism of gloves and socks syndrome, erythema infectiosum, acute polyarthralgia, aplastic crisis in persons with hemolytic anemia, and birth defects...
  74. ncbi Seroepidemiology of parvovirus B19 in the Frankfurt am Main area, Germany: evaluation of risk factors
    C Reinheimer
    Institute for Medical Virology, JW Goethe University Hospital, 60596 Frankfurt am Main, Germany
    Infection 38:381-5. 2010
    Parvovirus B 19 is a virus that is distributed by respiratory droplets. It is known to be an initiator of erythema infectiosum (children's fifth disease), with erythroblasts being the target cells of infection...
  75. ncbi Mumps-like syndrome owing to parvovirus B19: a brief report
    Mehmet Akin
    Department of Pediatrics, Haydarpaşa State Training Hospital, Istanbul, Turkey
    Ann Trop Paediatr 22:57-8. 2002
    Major manifestations of acute parvovirus B19 infection are usually erythema infectiosum, transient aplastic crisis and polyarthropathy...
  76. ncbi Human parvovirus B19 and pregnancy
    L J Anderson
    Division of Viral Diseases, Centers for Disease Control, Atlanta, Georgia
    Clin Perinatol 15:273-86. 1988
    ..The most common clinical manifestations of B19 infection are erythema infectiosum and aplastic crisis in patients with chronic hemolytic anemias.
  77. ncbi [Familial transient red cell aplasia from parvovirus B-19 infection]
    F Salvini
    Clinica Pediatrica dell Università di Milano, Ospedale San Paolo, Via A Di Rudini, 8, 20142 Milano
    Pediatr Med Chir 24:306-7. 2002
    ..In case of a family onset of hyperacute anemia it is necessary to consider a bone marrow aplastic crisis of the red series, induced by Parvovirus B19, especially if there is notice of an ongoing outbreak of erythema infectiosum.
  78. ncbi [Sero-diagnosis for human parvovirus B19 infection by IgM and IgG antibody capture method of enzyme-linked immunosorbent assay--study on an epidemic case of erythema infectiosum]
    Y Matsunaga
    National Institute of Health, Japan
    Kansenshogaku Zasshi 66:434-40. 1992
    ..Serially obtained serum samples from one erythema infectiosum (E.I.) patient were examined at once by this methods...
  79. ncbi [Prevalence of anti-human parvovirus antibody in pregnant women]
    N Yaegashi
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai
    Nihon Sanka Fujinka Gakkai Zasshi 42:162-6. 1990
    Human parvovirus B19 (B19) has been shown to be associated with erythema infectiosum. Recently, it was reported that when a pregnant woman is infected with B19, the fetus in her uterus sometimes becomes hydropic and results in a ..
  80. ncbi Quantitation of human parvovirus B19 DNA in erythema infectiosum and aplastic crisis
    Aki Ishikawa
    Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan
    J Med Virol 86:2102-6. 2014
    ..large-scale study quantitating levels of B19V DNA in common or representative B19V manifestations such as erythema infectiosum and aplastic crisis has been performed...
  81. ncbi Parvovirus-associated arthritis
    T L Moore
    Division of Rheumatolgy and Pediatric Rheumatology, Saint Louis University Health Sciences Center, Missouri 63104, USA
    Curr Opin Rheumatol 12:289-94. 2000
    Human parvovirus B19 is the cause of several distinct clinical syndromes. The most common is erythema infectiosum (fifth disease), a febrile exanthem occurring primarily in children...
  82. pmc Advances in human B19 erythrovirus biology
    Annabelle Servant-Delmas
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Virol 84:9658-65. 2010
    ..e., erythema infectiosum and erythroblastopenia crisis...
  83. ncbi Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus
    Miguel Aguilar-Bernier
    Department of Dermatology, University of Valladolid, Hospital Clinico Universitario, Valladolid, Spain
    J Am Acad Dermatol 54:896-9. 2006
    ..This case illustrates the difficulties in differentiating dysesthesia accompanying cutaneous manifestations of exanthem from neurologic disease on the basis of the clinical appearance alone...
  84. pmc Fatal myocarditis associated with acute parvovirus B19 and human herpesvirus 6 coinfection
    J Rohayem
    , , , 01307 Dresden, Germany
    J Clin Microbiol 39:4585-7. 2001
    ..We suggest that the HHV-6-induced immunosuppression enhanced dissemination of parvovirus B19, which led to fatal myocarditis...
  85. ncbi Serologic and virologic evidence for frequent intrauterine transmission of human parvovirus B19 with a primary maternal infection during pregnancy
    W C Koch
    Department of Pediatrics, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298, USA
    Pediatr Infect Dis J 17:489-94. 1998
    ..To define the intrauterine viral transmission rate during primary maternal parvovirus B19 infection and identify factors that may influence this rate...
  86. ncbi The seroprevalence of parvovirus B19 infection among to-be-married girls, pregnant women, and their neonates in Shiraz, Iran
    Mazyar Ziyaeyan
    Prof Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Namazi General Hospital, Shiraz, Iran
    Jpn J Infect Dis 58:95-7. 2005
    b>Erythema infectiosum (fifth Disease) is the major clinical manifestation of human parvovirus B19 (HPV B19) infection...
  87. ncbi [Five cases of erythema infectiosum in adults]
    T Takahashi
    Department of Medicine, Yame General Hospital
    Kansenshogaku Zasshi 75:469-72. 2001
    The similarities between clinical features of erythema infectiosum and collagen disease or other viral infections prompted us to investigate clinical manifestations and laboratory data of parvovirus B19 (B19) infection in adults...
  88. ncbi Prevalence of parvovirus B19-specific antibodies and of viral DNA in patients with endogenous uveitis
    Carsten Heinz
    Department of Ophthalmology, St Franziskus Hospital Muenster, Hohenzollernring 54, 48145, Muenster, Germany
    Graefes Arch Clin Exp Ophthalmol 243:999-1004. 2005
    Parvovirus B19 causes erythema infectiosum (fifth disease) in children...
  89. ncbi Outbreaks caused by parvovirus B19 in three Portuguese schools
    G Goncalves
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Euro Surveill 10:121-4. 2005
    ..This is to be taken into account in the design and conduct of surveillance activities, in the context of measles and rubella elimination programmes...
  90. ncbi Antibody-mediated opsonization of red blood cells in parvovirus B19 infection
    Wassim Chehadeh
    Virology Unit, Department of Microbiology, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13310 Kuwait
    Virology 390:56-63. 2009
    ..Furthermore, IgG samples preincubated with heated B19 particles exposing VP1-unique (VP1u) region were unable to opsonize RBCs. These observations clearly suggest a role for anti-VP1u IgG in the opsonization of RBC-bound B19 particles...
  91. ncbi Intrauterine therapy for parvovirus B19 infected symptomatic fetus using B19 IgG-rich high titer gammaglobulin
    Hideo Matsuda
    Department of Obstetrics and Gynecology, National Defense Medical College, Tokorozawa, Saitama Prefecture, Japan
    J Perinat Med 33:561-3. 2005
    ..Gammaglobulin injection into the peritoneal cavity is thus useful for treating hydrops fetalis while avoiding intrauterine blood-transfusion risks...
  92. ncbi [Papular-purpuric gloves and socks syndrome--a case report]
    Zorica Gajinov
    Klinika za kozne i venericne bolesti, Klinicki centar Novi Sad, Novi Sad
    Med Pregl 59:380-3. 2006
    ..It is triggered by a viral infection, most commonly by Human parvovirus B19 or Coxsackie group of viruses, but precise viral diagnosis is not obtained in all cases...
  93. ncbi Resistance to parvovirus B19 infection due to lack of virus receptor (erythrocyte P antigen)
    K E Brown
    Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, MD 20892
    N Engl J Med 330:1192-6. 1994
    ..whose erythrocytes do not have this receptor, would be naturally resistant to B19 infection, which causes erythema infectiosum. METHODS. Blood samples were collected from two populations in cross-sectional studies...
  94. pmc Inclusion of the central exon of parvovirus B19 precursor mRNA is determined by multiple splicing enhancers in both the exon and the downstream intron
    Wuxiang Guan
    Department of Microbiology, Molecular Genetics and Immunology, Kansas City, KS 66160, USA
    J Virol 85:2463-8. 2011
    ....
  95. ncbi Epidemiological and clinical features of erythema infectiosum in children in Novi Sad from 2000 to 2009
    Sonja Prcic
    Department of Dermatovenerology, Institute for Child and Youth Health Care of Vojvodina, Novi Sad, Serbia
    Vojnosanit Pregl 70:1081-4. 2013
    b>Erythema infectiosum (EI) is a common childhood illness, caused by human parvovirus B19...
  96. ncbi [Parvovirus B19]
    A Schindler
    Medizinische Poliklinik, Universitatsspital Zurich
    Praxis (Bern 1994) 95:609-15; quiz 616. 2006
  97. ncbi Clinical and epidemiological aspects of human parvovirus B19 infection in an urban area in Brazil (Niterói city area, State of Rio de Janeiro, Brazil)
    Solange Artimos de Oliveira
    Hospital Universitario Antonio Pedro, Niteroi, RJ, 24030 210, Brasil
    Mem Inst Oswaldo Cruz 97:965-70. 2002
    ....
  98. doi Parvovirus B19 infection as trigger of graft vs. host disease
    Gerhard Behre
    Department of Internal Medicine IV, Oncology and Hematology, University Hospital Halle Saale, Halle Saale, Germany
    Eur J Haematol 81:404. 2008
  99. pmc Chronic hepatitis caused by persistent parvovirus B19 infection
    Trine H Mogensen
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, DK 8200 Aarhus N, Denmark
    BMC Infect Dis 10:246. 2010
    ..infection with parvovirus B19 may lead to a diverse spectrum of clinical manifestations, including benign erythema infectiosum in children, transient aplastic crisis in patients with haemolytic anaemia, and congenital hydrops foetalis...
  100. ncbi Clinical presentations of parvovirus B19 infection
    Jessica T Servey
    David Grant Medical Center, Travis Air Force Base, California 94535, USA
    Am Fam Physician 75:373-6. 2007
    ..Parvovirus B19 usually infects children and causes the classic "slapped-cheek" rash of erythema infectiosum (fifth disease). The virus is highly infectious and spreads mainly through respiratory droplets...
  101. ncbi Infection and immunity for human parvovirus B19 in patients with febrile exanthema
    M S Pedranti
    Instituto de Virología Dr JM Vanella, Universidad Nacional de Cordoba, Argentina
    Epidemiol Infect 140:454-61. 2012
    ..All patients with acute B19V infection had rash and fever, 85·7% had adenopathy, and only 14·3% had arthropathy. This is the first follow-up study of markers of infection and immunity for B19V infection in Argentina...

Research Grants5

  1. SURROGATE ASSAY FOR B19 PARVOVIRUS SERUM NEUTRALIZATION
    GEETHA BANSAL; Fiscal Year: 1990
    ..B19 is implicates as a cause of human disease syndromes including mild illness with rash in children (erythema infectiosum), febrile illness with arthralgia or arthritis in adults, serious transient or chronic aplastic anemia in ..
  2. HUMAN PARVOVIRUS B19
    Arun Srivastava; Fiscal Year: 1992
    ..the human pathogenic parvovirus B19 believed to be the etiologic agent for several human diseases such as erythema infectiosum, transient aplastic crisis associated with several types of hemolytic anemias including sickle cell disease,..
  3. INTERNATIONAL CONFERENCE--PARVOVIRUS
    KENNETH BERNS; Fiscal Year: 1993
    ..The former type is a significant pathogen responsible for aplastic crisis in people with hemolytic anemia, erythema infectiosum, some forms of arthritis, and second trimester abortions...
  4. Short Tandem Repeat Polymorphisms in Cytomegalovirus
    James Bale; Fiscal Year: 2003
    ..Characterizing HCM' strains by STR analysis will facilitate future studies of HCMV evolution and will provide a novel means t to fingerprint HCMV strains. ..
  5. PULMONARY COMPLICATIONS IN PEDIATRIC SICKLE CELL DISEASE
    Kim Smith Whitley; Fiscal Year: 2002
    ....