Genomes and Genes
Summary: Pneumonia caused by a virus. (Dorland, 28th ed)
Publications238 found, 100 shown here
- Prospective study of respiratory viral infections in pediatric hemopoietic stem cell transplantation patientsRobbert G M Bredius
Department of Pediatrics, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
Pediatr Infect Dis J 23:518-22. 2004..We performed a prospective study to assess the impact of real time PCR diagnosis as well as protective isolation for community-acquired respiratory virus infections in pediatric patients undergoing hemopoietic stem cell transplantation...
- Human coronavirus infections in rural Thailand: a comprehensive study using real-time reverse-transcription polymerase chain reaction assaysRyan K Dare
Respiratory and Gastroenteritis Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 196:1321-8. 2007..We sought to determine whether infections with human coronaviruses (HCoVs) 229E, OC43, HKU1, and NL63 are associated with pneumonia and to define the epidemiology of HCoV infection in rural Thailand...
- Viral pneumonia in older adultsAnn R Falsey
Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
Clin Infect Dis 42:518-24. 2006..A H3N2 and respiratory syncytial virus are the most commonly identified viral pathogens in older adults with viral pneumonia. As diagnostic tests such as reverse-transcription polymerase chain reaction become more widely used, the ..
- Association of normal weather periods and El Niño events with hospitalization for viral pneumonia in females: California, 1983-1998K L Ebi
EPRI, 3412 Hillview Ave, Palo Alto, CA 94304, USA
Am J Public Health 91:1200-8. 2001This study examined associations between weather and hospitalizations of females for viral pneumonia during normal weather periods and El Niño events in the California counties of Sacramento and Yolo, San Francisco and San Mateo, and ..
- Influenza virus infection in racing greyhoundsKyoung Jin Yoon
Emerg Infect Dis 11:1974-6. 2005
- Non-specific host response markers in the differentiation between pneumococcal and viral pneumonia: what is the most accurate combination?Matti Korppi
Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland
Pediatr Int 46:545-50. 2004..The aim of the present paper was to determine if there is a combination of these four host response markers and chest radiograph findings suitable for differentiating pneumococcal from viral etiology of pneumonia...
- Polymerase chain reaction is more sensitive than viral culture and antigen testing for the detection of respiratory viruses in adults with hematological cancer and pneumoniaLeontine J R Van Elden
Eijkman Winkler Institute of Medical Microbiology, Infectious Diseases and Inflammation, Department of Virology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
Clin Infect Dis 34:177-83. 2002....
- Differentiation of bacterial and viral pneumonia in childrenR Virkki
Department of Diagnostic Imaging, Turku University Hospital, Kiinamyllynkatu 4 8, 20520 Turku, Finland
Thorax 57:438-41. 2002....
- Update on avian influenza A (H5N1) virus infection in humansAbdel Nasser Abdel-Ghafar
Ministry of Health and Population, Cairo
N Engl J Med 358:261-73. 2008
- A role for Streptococcus pneumoniae in virus-associated pneumoniaShabir A Madhi
University of the Witwatersrand Medical Research Council National Institute for Communicable Diseases Respiratory and Meningeal Pathogens Research Unit, Atlanta 30332, USA
Nat Med 10:811-3. 2004..These data suggest that the pneumococcus has a major role in the development of pneumonia associated with these viruses and that viruses contribute to the pathogenesis of bacterial pneumonia...
- Respiratory syncytial virus epidemiology in a birth cohort from Kilifi district, Kenya: infection during the first year of lifeD James Nokes
Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
J Infect Dis 190:1828-32. 2004..RSV contributed significantly to total LRTI disease in this vaccine-target group...
- Complications of viral influenzaMichael B Rothberg
Division of General Medicine, Baystate Medical Center, Springfield, MA 01199, USA
Am J Med 121:258-64. 2008..During influenza season, treatment of pneumonia should include empiric coverage for this pathogen. Neuromuscular and cardiac complications are unusual but may manifest in persons of any age...
- Reovirus infection in rat lungs as a model to study the pathogenesis of viral pneumoniaM J Morin
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, USA
J Virol 70:541-8. 1996..We propose that experimental reovirus infection in the lungs can serve as a model for the pathogenesis of viral pneumonia in which pulmonary inflammation results following direct infection of lung epithelial cells.
- Aetiology of community-acquired pneumonia: serological results of a paediatric surveyMassimiliano Don
Department of Paediatrics, School of Medicine DPMSC, University of Udine, Udine, Italy
Scand J Infect Dis 37:806-12. 2005..pneumoniae at >2 y of age and emphasize the emerging role of hMPV. The high proportion of mixed viral-bacterial infections highlights the need to treat all children with CAP with antibiotics...
- Viral pneumoniae in children: incidence and aetiologyC A Sinaniotis
Second Department of Paediatrics, University of Athens School of Medicine, Athens, Greece
Paediatr Respir Rev 5:S197-200. 2004..Viral pneumonias frequently are complicated by bacterial infections and mixed infections are identified in 30% of the cases. The precise role of viruses and bacteria in these cases, remains to be clarified...
- Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in CaliforniaJanice K Louie
California Department of Public Health, 850 Marina Bay Pkwy, Richmond, CA 94804, USA
JAMA 302:1896-902. 2009..Pandemic influenza A(H1N1) emerged rapidly in California in April 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A(H1N1) disproportionately affects younger ages and causes generally mild disease...
- Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipientsJanet A Englund
Children s Hospital and Regional Medical Center, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, Washington 98105, USA
Ann Intern Med 144:344-9. 2006..Human metapneumovirus (hMPV), a recently discovered respiratory virus, is associated with clinical disease in young and elderly persons...
- Serum procalcitonin concentrations in bacterial pneumonia in children: a negative result in primary healthcare settingsMatti Korppi
Department of Paediatrics, Kuopio University Hospital, Kuopio University, Kuopio, Finland
Pediatr Pulmonol 35:56-61. 2003..viral infection). We conclude that serum PCT measurements have no role in the diagnosis of bacterial CAP in children in primary healthcare settings...
- Development and validation of a clinical prediction rule to distinguish bacterial from viral pneumonia in childrenLaura Moreno
Division of Pulmonology, Hospital de Niños de la Santísima Trinidad, Universidad Nacional de Cordoba, Cordoba, Argentina
Pediatr Pulmonol 41:331-7. 2006Distinguishing bacterial from viral pneumonia on admission to the hospital could guide the decision of whether or not to use antibiotics...
- Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?Thomas C Luke
Bureau of Medicine and Surgery, U S Navy, Washington, DC, USA
Ann Intern Med 145:599-609. 2006..Treatments for H5N1 influenza are unsatisfactory, and convalescent human plasma containing H5N1 antibodies could be an effective therapy during outbreaks and pandemics...
- Viral etiology of pneumonia in a cohort of newborns till 24 months of age in Rural Mirzapur, BangladeshKhundkar Hasan
ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
Scand J Infect Dis 38:690-5. 2006..Children living in a one-room house were 3 times more likely to develop viral pneumonia (odds ratio (OR) = 3.67, CI 1.05-12.83) than children living in a larger house...
- Local CD11c+ MHC class II- precursors generate lung dendritic cells during respiratory viral infection, but are depleted in the processHongwei Wang
Department of Respiratory Medicine, National Heart and Lung Institute and Wright Fleming Institute of Infection and Immunity, Imperial College London, Norfolk Place, London, United Kingdom
J Immunol 177:2536-42. 2006..This depletion of local DC precursors in respiratory viral infections may be important in explaining complex interactions between multiple and intercurrent pulmonary infections...
- The value of clinical features in differentiating between viral, pneumococcal and atypical bacterial pneumonia in childrenMatti Korppi
Paediatric Research Centre, Tampere University and University Hospital, Tampere, Finland
Acta Paediatr 97:943-7. 2008..To evaluate the value of clinical features in differentiating between viral, pneumococcal and atypical bacterial pneumonia in children...
- Open-lung biopsy in patients with acute respiratory distress syndromeL Papazian
Service de Reanimation Polyvalente, Hopital Sainte Marguerite, Marseille, France
Anesthesiology 88:935-44. 1998..The aim of this observational case series was to evaluate the safety and utility of open-lung biopsy (OLB) performed in patients receiving ventilatory support who had persistent ARDS despite negative bacterial cultures...
- Clinical response to antibiotic therapy for community-acquired pneumoniaTaina Juven
Department of Paediatrics, Turku University Hospital, PL 52, 20521, Turku, Finland
Eur J Pediatr 163:140-4. 2004..Expensive and time-consuming microbiological investigations are not required once bacterial sepsis has been excluded...
- Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in MexicoRogelio Perez-Padilla
National Institute of Respiratory Diseases, Mexico City, Mexico
N Engl J Med 361:680-9. 2009....
- Mixed microbial aetiology of community-acquired pneumonia in childrenMatti Korppi
Department of Paediatrics, Kuopio University Hospital, Finland
APMIS 110:515-22. 2002..Current guidelines recommend antibiotic therapy for all community-acquired pneumonia cases in children...
- Controls for lung dendritic cell maturation and migration during respiratory viral infectionMitchell H Grayson
Division of Allergy and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
J Immunol 179:1438-48. 2007..Our results indicate that pDCs and cDCs respond distinctly to respiratory paramyxoviral infection with patterns of movement that should serve to coordinate the innate and adaptive immune responses, respectively...
- Etiology of community-acquired pneumonia in hospitalized school-age children: evidence for high prevalence of viral infectionsM N Tsolia
Second Department of Pediatrics, University of Athens School of Medicine, P and A Kyriakou Children s Hospital, Athens, Greece
Clin Infect Dis 39:681-6. 2004..Community-acquired pneumonia (CAP) in young children is most commonly associated with viral infections; however, the role of viruses in CAP of school-age children is still inconclusive...
- 8-nitroguanosine formation in viral pneumonia and its implication for pathogenesisTakaaki Akaike
Department of Microbiology, Kumamoto University School of Medicine, Kumamoto 860 0811, Japan
Proc Natl Acad Sci U S A 100:685-90. 2003..The present data constitute a demonstration of 8-nitroguanosine formation in vivo and suggest a potential role for NO-induced nitrative stress in viral pathogenesis...
- Clinical review: primary influenza viral pneumoniaJordi Rello
Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Tarragona, Spain
Crit Care 13:235. 2009..Ensuring an appropriate oxygenation and ventilation strategy, as well as prompt initiation of antiviral therapy, is essential in management...
- Clinical significance of herpes simplex virus in the lower respiratory tract of critically ill patientsK Camps
Department of Microbiology, University Hospital of Antwerp, Wilrijkstraat 10, Edegem, Belgium
Eur J Clin Microbiol Infect Dis 21:758-9. 2002
- Histone acetylation and deacetylation: importance in inflammatory lung diseasesP J Barnes
National Heart and Lung Institute, Imperial College, London SW3 6LY, UK
Eur Respir J 25:552-63. 2005..The reduction in histone deacetylase activity can be restored by theophylline, which may be able to reverse steroid resistance in chronic obstructive pulmonary disease and other inflammatory diseases...
- Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized childrenIan C Michelow
Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Pediatrics 113:701-7. 2004..The objective of this study was to determine as precisely as possible the epidemiology and morbidity of community-acquired pneumonia in hospitalized children...
- Usefulness of procalcitonin levels in community-acquired pneumonia according to the patients outcome research team pneumonia severity indexMar Masia
Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Camí de la Almazara S N 03203 ELCHE, Alicante, Spain
Chest 128:2223-9. 2005..To evaluate the usefulness of procalcitonin serum levels as a predictor of etiology and prognosis in adult patients with community-acquired pneumonia (CAP) when they are stratified according to severity...
- Procalcitonin in children admitted to hospital with community acquired pneumoniaF Moulin
Department of Pediatrics, , 82 Av Denfert-Rochereau, 75014 Paris, France
Arch Dis Child 84:332-6. 2001..1 microg/l in 86% of patients with bacterial infection (including Mycoplasma and bacterial superinfection of viral pneumonia)...
- Serum procalcitonin, C-reactive protein and interleukin-6 for distinguishing bacterial and viral pneumonia in childrenP Toikka
Department of Pediatrics, Turku University Hospital, Finland
Pediatr Infect Dis J 19:598-602. 2000..IL-6) concentrations were measured in 126 children hospitalized for community-acquired, radiologically confirmed pneumonia to assess whether these host response values could be used to distinguish bacterial from viral pneumonia.
- Influenza A pneumonia with rhabdomyolysisS E Morton
Veterans Affairs Medical Center, Mountain Home, Tenn, USA
South Med J 94:67-9. 2001....
- Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspectsLuiz Tadeu Moraes Figueiredo
Departamento de Clinica Medica, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP, Brasil
J Bras Pneumol 35:899-906. 2009..These types of pneumonia are commonly caused by influenza A and B; parainfluenza 1, 2 and 3; respiratory syncytial virus; or adenovirus. We also address the types of pneumonia caused by hantaviruses, metapneumoviruses and rhinoviruses...
- Human metapneumovirus pneumonia in children: results of an Italian study and mini-reviewMassimiliano Don
Paediatric Department, School of Medicine, DPMSC, University of Udine, Italy
Scand J Infect Dis 40:821-6. 2008..The figure was about 5% in the present and in the only earlier paediatric CAP study. Thus, hMPV is a real but rare cause of paediatric CAP, although seroconversion to hMPV in most children takes place in early childhood...
- Identification of adenovirus, influenza virus, parainfluenza virus, and respiratory syncytial virus by two kinds of multiplex polymerase chain reaction (PCR) and a shell vial culture in pediatric patients with viral pneumoniaJong Han Lee
Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea
Yonsei Med J 51:761-7. 2010..Two kinds of multiplex polymerase chain reaction (PCR) and a commercial shell vial viral culture were performed to identify causative agents in pediatric patients...
- Viral community-acquired pneumonia in nonimmunocompromised adultsAndres De Roux
Servei de Pneumologia, Institut Clinic de Pneumologia i Cirurgia Toracica, Barcelona, Spain
Chest 125:1343-51. 2004..Viral community-acquired pneumonia (CAP) has been poorly studied and clinically characterized. Using strict criteria for inclusion, we studied this type of infection in a large series of hospitalized adults with CAP...
- Incidence and clinical features of hospitalization because of respiratory syncytial virus lower respiratory illness among children less than two years of age in a rural Asian settingI G Djelantik
Program for Appropriate Technology in Health, Seattle WA, USA
Pediatr Infect Dis J 22:150-7. 2003..Despite this few reports on respiratory syncytial virus (RSV) lower respiratory illness disease burden exist from rural areas of the developing world, and none exist for Indonesia...
- H5N1 Virus Attachment to Lower Respiratory TractDebby van Riel
Department of Virology, Erasmus Medical Center, 3015 GE Rotterdam, Netherlands
Science 312:399. 2006..These findings may explain, at least in part, the localization and severity of H5N1 viral pneumonia in humans. They also identify the cat and the ferret as suitable experimental animals based on this criterion.
- Viral pneumoniaMaria Angeles Marcos
Department of Microbiology, Hospital Clinic i Provincial de Barcelona, Spain
Curr Opin Infect Dis 22:143-7. 2009..The purpose of the present article is to review several issues of viral infection in CAP in light of recent studies that included exhaustive evaluation of viruses...
- Evaluation by survival analysis on effect of traditional Chinese medicine in treating children with respiratory syncytial viral pneumonia of phlegm-heat blocking Fei syndromeYan Yang
Nanjing University of Traditional Chinese Medicine, Nanjing, 210029, China
Chin J Integr Med 15:95-100. 2009To objectively evaluate the clinical effect of traditional Chinese medicine in treating children's respiratory syncytial viral pneumonia (RSVP) of phlegm-heat blocking Fei syndrome (PHBFS).
- Viral pneumonia after hematopoietic stem cell transplantation: high-resolution CT findingsJeffrey P Kanne
Department of Radiology, Vancouver General Hospital, Vancouver BC, Canada
J Thorac Imaging 22:292-9. 2007..Findings of viral pneumonia on HRCT include small poorly defined centrilobular nodules and patchy, often bilateral, areas of ..
- Viral pneumonia as a serious complication of etanercept therapyDavey Smith
Ann Intern Med 136:174. 2002
- Medical treatment of viral pneumonia including SARS in immunocompetent adultV C C Cheng
Centre of Infection, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
J Infect 49:262-73. 2004Since no randomized controlled trials have been conducted on the treatment of viral pneumonia by antivirals or immunomodulators in immunocompetent adults, a review of such anecdotal experience are needed for the more rational use of such ..
- Diagnostic value of bronchoalveolar lavage in community-acquired pneumonia in a routine setting: a study on patients treated in a Finnish university hospitalUlla Hohenthal
Department of Medicine, Turku University Central Hospital, Kiinamyllynkatu 4 8, 20520 Turku, Finland
Scand J Infect Dis 36:198-203. 2004..In a subgroup of slowly responding pneumonia, the procedure was of some usefulness even after commencement of antimicrobial treatment...
- Cytomegalovirus pneumonia in transplant recipientsMichael G Ison
Transplant Infectious Disease and Compromised Host Program, Infectious Disease Division, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Chest Med 26:691-705, viii. 2005..Invasive procedures are often required for the optimal management of such infections. The use of sensitive and quantitative assays have greatly improved the outcomes of CMV infection...
- Comparison of corticosteroids for treatment of respiratory syncytial virus bronchiolitis and pneumonia in cotton ratsMartin G Ottolini
Department of Pediatric, F Edward Hébert School of Medicine of the Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Antimicrob Agents Chemother 46:2299-302. 2002..Triamcinolone and methylprednisolone proved to be more effective than dexamethasone in reducing lung pathology. No recurrence of viral replication or pulmonary pathology followed the cessation of therapy...
- Respiratory syncytial virus infection in 406 hospitalized premature infants: results from a prospective German multicentre databaseArne Simon
Department of Pediatric Hematology and Oncology, Children s Hospital Medical Center, University of Bonn, Adenauerallee 119, 53113 Bonn, Germany
Eur J Pediatr 166:1273-83. 2007..From the perspective of our results, the statements of the German Society of Paediatric Infectious Diseases considering the use of passive immunisation (2003) seem reasonable...
- Signs and symptoms indicative of community-acquired pneumonia in infants under six monthsMaria de Fatima Bazhuni Pombo March
Martagão Gesteira Pediatric Institute, Dept of Pediatrics, Medical School, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Braz J Infect Dis 9:150-5. 2005Evaluation of the clinical signs and symptoms predicting bacterial and viral pneumonia, in accordance with the Brazilian National Control Program for Acute Respiratory (ARI).
- Etiologic agents and outcome determinants of community-acquired pneumonia in urban children: a hospital-based studyAbdul Wahab B R Johnson
Department of Pediatrics, University College Hospital, Ibadan, Nigeria
J Natl Med Assoc 100:370-85. 2008....
- Radiological findings in children with acute pneumonia: age more important than infectious agentH Wahlgren
Department of Pediatric Radiology, Astrid Lindgren s Children s Hospital, Karolinska Hospital, Stockholm, Sweden
Acta Radiol 46:431-6. 2005..To evaluate whether radiological findings and healing time in children with pneumonia are correlated to etiologic agent...
- Pneumonia in pregnancyWilliam H Goodnight
Division of Maternal Fetal Medicine, Medical University of South Carolina, Charleston, SC, USA
Crit Care Med 33:S390-7. 2005..This review will identify maternal risk factors, potential complications, and prenatal outcomes associated with pneumonia and describe the contemporary management of the varied causes of pneumonia in pregnancy...
- Invasive pulmonary aspergillosis: frequency and meaning of the "hypodense sign" on unenhanced CTM Horger
Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Strasse 3, 72076 Tubingen
Br J Radiol 78:697-703. 2005..The hypodense sign is recognizable also on unenhanced CT, when a narrower lung window setting is used...
- Population-based incidence of severe pneumonia in children in Kiel, GermanyJ A Weigl
Pediatric Infectious Diseases, Department of General Pediatrics, Christian Albrechts University
Klin Padiatr 217:211-9. 2005..Elaborated data on the descriptive epidemiology of community-acquired pneumonia (CAP) are a prerequisite to estimate the impact of new vaccines...
- Community-acquired pneumonia in childrenConstantine A Sinaniotis
Second Department of Pediatrics, University of Athens School of Medicine, Laiko General Hospital, Athens, Greece
Curr Opin Pulm Med 11:218-25. 2005..This review highlights recent developments in the diagnosis, etiology, therapy, and prevention of community-acquired pneumonia in children...
- The correct approach to community-acquired pneumonia in immunocompetent adults: review of current guidelinesSergio Carbonara
Clinic of Infectious Diseases, University of Bari, Italy
New Microbiol 31:1-18. 2008..Herein, the authors review and discuss some of the main current guidelines for CAP management, highlighting their differences and similarities...
- [Respiratory viruses: the most common, the most often overlooked]Francisco López-Medrano
Enferm Infecc Microbiol Clin 26:67-8. 2008
- Defining pneumonia in critically ill infants and childrenJoanne M Langley
Clinical Trials Research Centre, IWK Health Center, and the Department of Pediatrics, Dalhousie University, Halifax, Canada
Pediatr Crit Care Med 6:S9-S13. 2005....
- Viruses in community-acquired pneumonia in children aged less than 3 years old: High rate of viral coinfectionGustavo Cilla
Microbiology Department, Hospital Donostia, San Sebastian, Spain
J Med Virol 80:1843-9. 2008..It is concluded that viral coinfections are frequent in children aged less than 3 years old with community-acquired pneumonia and can be a poor prognostic factor...
- The burden of pneumonia in children in the developed worldTalal Farha
The John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK
Paediatr Respir Rev 6:76-82. 2005..This does not include family and social costs. There is potential for new vaccine strategies to decrease childhood pneumonia...
- Role of rhinovirus in hospitalized infants with respiratory tract infections in SpainCristina Calvo
Pediatrics Department, Severo Ochoa Hospital, Virology Service ISCIII National Microbiology Center, Madrid, Spain
Pediatr Infect Dis J 26:904-8. 2007..Our aim was to describe rhinovirus infections in hospitalized children, under 2 years of age, and to compare these with patients infected with respiratory syncytial virus (RSV)...
- Evaluation of chronic infectious interstitial pulmonary disease in children by low-dose CT-guided transthoracic lung biopsyChristoph M Heyer
Institute of Diagnostic Radiology, Interventional Radiology and Nuclear Medicine, BG Clinics Bergmannsheil, Ruhr University of Bochum, Germany
Eur Radiol 15:1289-95. 2005..Open lung biopsy is an invasive procedure with major potential complications. Transthoracic lung biopsy (TLB) guided by computed tomography (CT) is a less-invasive well-established procedure in adults...
- The role of respiratory viral infections among children hospitalized for community-acquired pneumonia in a developing countryCristiana M Nascimento-Carvalho
Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil
Pediatr Infect Dis J 27:939-41. 2008..Rhinovirus (21%) and Streptococcus pneumoniae (21%) were the most common pathogens. Our results demonstrate the importance of viral and pneumococcal infections among those patients...
- Treatment of adenovirus pneumonia with cidofovir in pediatric lung transplant recipientsMinh L Doan
Department of Pediatrics, Section of Pulmonology, Congenital Heart Surgery Service, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas 77030, USA
J Heart Lung Transplant 26:883-9. 2007..Cidofovir allows for directed therapy but can result in nephrotoxicity. We report our experience with cidofovir for the treatment of adenovirus pneumonia in pediatric lung transplant recipients...
- [Current news about epidemiology of syncytial respiratory virus infection]Emilio Palumbo
Recenti Prog Med 99:237-9. 2008..In these patients, the prophylaxis with palivizumab is very important to prevent chronic pulmonary diseases...
- A population-based assessment of the disease burden of consolidated pneumonia in hospitalized children under five years of ageMaria Hortal
Ministry of Health, Maternal and Child Health Program, Bv Artigas 1550, Montevideo 11600, Uruguay
Int J Infect Dis 11:273-7. 2007..Therefore, our study aimed to estimate the burden of pneumonia in hospitalized children...
- Influenza A community-acquired pneumonia in East London infants and young childrenMatthew Laundy
Department of Child Health, Barts and the London Hospital NHS, Queen Mary School of Medicine and Dentistry, University of London, London, UK
Pediatr Infect Dis J 22:S223-7. 2003..The aim of this study was to determine the relative contributions of different etiologic agents to CAP in children...
- Pulmonary dysfunction in pediatric hematopoietic stem cell transplant patients: overview, diagnostic considerations, and infectious complicationsJ Michael Collaco
Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, Maryland
Pediatr Blood Cancer 49:117-26. 2007....
- [Pneumonia - pathogen-based or constellation-based therapy?]A Kuhnke
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13 353 Berlin
Internist (Berl) 47:S14-9. 2006..These factors must be considered at the beginning of any treatment. Pathogen-based treatment has to be switched to constellation-based treatment...
- Antibiotics in childhood pneumoniaKatherine A Hale
Department of Allergy, The Children s Hospital at Westmead, Australia
Paediatr Respir Rev 7:145-51. 2006..The route and duration of antibiotic therapy, the role of emerging pathogens and the impact of pneumococcal resistance and conjugate pneumococcal vaccines are also discussed...
- Airflow decline after myeloablative allogeneic hematopoietic cell transplantation: the role of community respiratory virusesVeronique Erard
Division of Clinical Research, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109 1024, USA
J Infect Dis 193:1619-25. 2006..Thus, community respiratory virus-associated airflow decline seems to be specific to viral species and infection localization...
- Mixed community-acquired pneumonia in hospitalised patientsA de Roux
Servei de Pneumologia i Allergia Respiratoria, Institut Clinic del Torax, Facultad de Medicina, Universitat de Barcelona, and Servei de Malalties Infeccioses, Hospital Clinic i Provincial de Barcelona, Spain
Eur Respir J 27:795-800. 2006..In conclusion, mixed pneumonia occurs in >10% of cases with community-acquired pneumonia requiring hospitalisation...
- Decline in respiratory syncytial virus hospitalizations in a region with high hospitalization rates and prolonged seasonRosalyn J Singleton
Alaska Native Tribal Health Consortium, Anchorage, AK, USA
Pediatr Infect Dis J 25:1116-22. 2006..S. general infant population rate. We describe trends in lower respiratory tract infection (LRTI) and RSV hospitalizations in YK children from 1994 to 2004...
- A contributive result of open-lung biopsy improves survival in acute respiratory distress syndrome patientsLaurent Papazian
Service de Reanimation Medicale, Hopital Sainte Marguerite, Universite de la Mediterranee, Marseille, France
Crit Care Med 35:755-62. 2007..The aim of this study was therefore to determine the rate of contributive open-lung biopsy and whether it improved the prognosis of ARDS patients...
- Effective treatment strategies for paediatric community-acquired pneumoniaMaria Atkinson
Nottingham University Hospitals NHS Trust, Nottingham, UK
Expert Opin Pharmacother 8:1091-101. 2007..This review describes the difficulties encountered in diagnosing community-acquired pneumonia, aetiology, treatment strategies with recommendations and highlights areas for further research...
- Evaluation of a nested-PCR assay for Streptococcus pneumoniae detection in pediatric patients with community-acquired pneumoniaC Mayoral
Sección Bacteriología, Practica Profesional, Facultad de Bioquimica y Ciencias Biologicas, Universidad Nacional del Litoral, Av Freyre 2150 3000 Santa Fe, Argentina
Rev Argent Microbiol 37:184-8. 2005..The application of the strategy described in this paper substantially seems to improve the diagnostic process in a determinate group: blood culture-negative children with pneumonia...
- Hyper- and hypoglycemia in children with community-acquired pneumoniaMassimiliano Don
Pediatric Department, School of Medicine, DPMSC, University ofUdine, Italy
J Pediatr Endocrinol Metab 21:657-64. 2008..However, about 4% of the patients had hypoglycemia, which could be explained by reduced calorie intake during acute infection or by the effect of stress-induced cytokines...
- [Histopathological findings of pulmonary complications in 16 patients who received allogeneic hematopoietic stem cell transplants]Hiroatsu Iida
Department of Hematology, Meitetsu Hospital
Rinsho Ketsueki 46:1273-8. 2005..Efforts to reduce RRT such as using a reduced intensity regimen and careful tapering off of immunosupressants are expected to lead to a decrease in non-infectious pulmonary complications...
- CT findings in immunocompromised patients with pulmonary infectionsFigen Başaran Demirkazik
Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey
Diagn Interv Radiol 14:75-82. 2008..To evaluate computed tomography (CT) findings of pulmonary infections in immunocompromised patients with hematologic malignancies, and to detect the accuracy of first-choice diagnoses...
- Fiberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary disease in children with primary immunodeficiency and cancerO Efrati
Pediatric Pulmonology Unit, Safra Children s Hospital, The Sheba Medical Center, Tel Hashomer, affiliated to the Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel
Pediatr Blood Cancer 48:324-9. 2007..A definite diagnosis may be achieved in these situations by fiberoptic bronchoscopy (FOB) and bronchoalveolar lavage (BAL)...
- [Bronchopulmonary infections in the enfant and the child]Christophe Marguet
Unité de pneumologie et allergologie pédiatrique, centre de ressource et de compétence mixte pour la mucoviscidose, Departement de Pediatrie, Centre Hospitalier Universitaire de Rouen, Hopital Charles Nicolle, 76031 Rouen
Rev Prat 57:1237-44. 2007
- Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: a retrospective study at a major cancer centerRoy F Chemaly
Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Medicine (Baltimore) 85:278-87. 2006..HSCT recipients and patients with hematologic malignancies who develop upper respiratory infection due to CRVs should be considered for antiviral therapy of proven efficacy to reduce the risk of pneumonia and death...
- Impact of HIV on childhood respiratory illness: differences between developing and developed countriesS M Graham
Malawi Liverpool Wellcome Trust Clinical Research Programme and Department of Paediatrics, College of Medicine, University of Malawi, Blantyre, Malawi
Pediatr Pulmonol 36:462-8. 2003..Autopsy studies have provided a lot of useful data, but more prospective clinical and intervention studies from different parts of the region are needed in order to improve clinical diagnosis and management...
- Concurrent serious bacterial infections in 2396 infants and children hospitalized with respiratory syncytial virus lower respiratory tract infectionsKevin Purcell
Texas A and M University Kingsville School of Pharmacy, Kingsville, Texas, USA
Arch Pediatr Adolesc Med 156:322-4. 2002..Physicians were concerned about the possibility of concurrent serious bacterial infections, especially in infants younger than 3 months and in those with infiltrates present on the chest x-ray films...
- Reappraisal of lung tap: review of an old method for better etiologic diagnosis of childhood pneumoniaE Vuori-Holopainen
Helsinki University Central Hospital, Hospital for Children and Adolescents, FIN-00029 Helsinki, Finland
Clin Infect Dis 32:715-26. 2001....
- Etiological agents of lower respiratory tract infections in Japanese childrenKei Numazaki
Research Group of Hokkaido for Pediatric Respiratory Tract Infections, Department of Pediatrics, Sapporo Medical University School of Medicine, Japan
In Vivo 18:67-71. 2004..The importance of M. pneumoniae and RS virus in the etiology of lower respiratory infections in Japanese children was confirmed...
- Lower respiratory tract infection in hospitalized childrenChong Chia Yin
Department of Paediatric Medicine, KK Women s and Children s Hospital, Republic of Singapore
Respirology 8:83-9. 2003..The aim of the present study was to investigate the aetiology and antibiotic-resistance patterns of community-acquired lower respiratory tract infection (LRTI) in 1999 and compare it with data from 1995 and 1988...
- An outbreak of respiratory syncytial virus infection in a bone marrow transplant unit: effect on engraftment and outcome of pneumonia without specific antiviral treatmentA Abdallah
Department of Clinical Haematology and Bone Marrow Transplantation Unit, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
Bone Marrow Transplant 32:195-203. 2003..Furthermore, RSV infection in the pre-engraftment period after autologous transplantation was associated with delayed engraftment...
- [Seropositivity against atypical pneumonia agents demonstrated in patients with community-acquired pneumonia]Murat Sayan
Dokuz Eylul Universitesi Tip Fakultesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Izmir
Mikrobiyol Bul 37:247-53. 2003..029). Since the type of the pathogens causing CAP are of crucial importance both for the epidemiological purposes and for planning the empirical treatment strategies, more detailed multicenter studies should be performed in our country...
- [Respiratory syncytial virus infection and asthma]M A Martin Mateos
Servicio de Inmunología y Alergia, Unidad integrada de Pediatria, Hospital Clínico Hospital San Juan de Dios, Universidad de Barcelona
Allergol Immunopathol (Madr) 29:140-6. 2001..Serious forms of bronchiolitis due to RSV are more frequent in atopic individuals. The appearance of extrinsic asthma is more frequent in children who have previously had RSV bronchiolitis than in those who have not...
- Community-acquired pneumonia in infants and childrenMichael Ostapchuk
Department of Family and Geriatric Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
Am Fam Physician 70:899-908. 2004..Childhood immunization has helped decrease the incidence of invasive Haemophilus influenzae type B infection, and the newly introduced heptavalent pneumococcal vaccine may do the same for Streptococcus pneumoniae infections...
- Editorial overview: Infectious diseasesAlimuddin I Zumla
Curr Opin Pulm Med 9:163-5. 2003
- The discriminative value of C-reactive protein levels in distinguishing between community-acquired bacteraemic and respiratory virus-associated lower respiratory tract infections in HIV-1-infected and -uninfected childrenSanjay G Lala
Department of Paediatrics and Child Health, University of the Witwatersrand, Johannesburg, South Africa
Ann Trop Paediatr 22:271-9. 2002....
- Detection of human influenza virus in Yucatan, MexicoGuadalupe Ayora-Talavera
Laboratorio de Hematologia, Centro de Investigaciones Regionales Dr Hideyo Noguchi, Universidad Autonoma de Yucatan
Rev Invest Clin 54:410-4. 2002....
- Assessment of vitamin A status with the relative-dose-response test in Peruvian children recovering from pneumoniaCharles B Stephensen
Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, USA
Am J Clin Nutr 76:1351-7. 2002..The relative-dose-response (RDR) test is used to identify subjects with marginal liver vitamin A stores, but its use has not been evaluated during episodes of infection...
- [Various sides of influenza, part I--structure, replication, changeability of influenza viruses, clinical course of the disease, immunological response and laboratory diagnostics]Magdałena K Machała
Krajowy Ośrodek ds Grypy, Samodzielna Pracownia ds Grypy, Paistwowy Zakład Higieny w Warszawte
Pol Merkur Lekarski 21:270-6. 2006..Reasons for the severe course of the disease or even death are post-influenza complications, e.g. viral pneumonia and bronchitis, bronchiolitis in children, secondary bacterial pneumonia, otitis media, myocarditis and ..
- Epidemiology and Etiology of Hospitalized Pneumonia in ChildrenKrow Ampofo; Fiscal Year: 2010..etiology and outcomes of pediatric influenza-associated pneumonia in Salt Lake County, including primary viral pneumonia, viral and bacterial co-infection, and post-influenza bacterial pneumonia...
- Single RNA sensitive probes for studying viral replication and buddingPhilip J Santangelo; Fiscal Year: 2013..PUBLIC HEALTH RELEVANCE: Human respiratory syncytial virus (hRSV), an RNA virus, is the leading cause of viral pneumonia, bronchiolitis, respiratory failure, mechanical ventilation, and viral death in infants in the USA and ..
- Mucosal Immune Barrier in Infection and ImmunityKeith E Mostov; Fiscal Year: 2012..Mucosal infections include bacterial and viral pneumonia, SARS, TB, AIDS and other sexually transmitted diseases, numerous opportunistic, emerging and re-emerging ..
- Epidemiology and Etiology of Hospitalized Pneumonia in ChildrenKrow Ampofo; Fiscal Year: 2013..etiology, and outcomes of pediatric influenza-associated pneumonia in Salt Lake County, including primary viral pneumonia, viral and bacterial co-infection, and post-influenza bacterial pneumonia...
- Structural studies of respiratory syncytial virusElizabeth R Wright; Fiscal Year: 2013..To answer these questions, we are using the A2 strain of RSV that causes bronchiolitis, viral pneumonia, and death in young children, the elderly, and immuno-compromised individuals...
- MicroRNA biology and the host response to influenza virus infectionJasmine T Perez; Fiscal Year: 2010..infection;it results in respiratory disease ranging from subclinical symptoms to life-threatening primary viral pneumonia. Despite the availability of a yearly vaccine, it is estimated that an average of 360,000 deaths/year can be ..
- Inflammatory Response and SARS Pathogenesis: An in vitro ModelCHIEN TE TSENG; Fiscal Year: 2009..Because SARS is considered a viral pneumonia, likely caused by unregulated and often excess innate inflammatory responses, a full understanding is ..
- PATHOBIOCHEMISTRY OF ACUTE LUNG INJURYJohn Hoidal; Fiscal Year: 2000..expression in mice and to evaluate effects of this manipulation in clinically relevant models of lung injury (Viral Pneumonia, reperfusion injury and sepsis)...
- COLLECTINS AND LUNG DEFENSEAnn Marie LeVine; Fiscal Year: 2003..Such data may be useful in the future in designing treatment and prevention of viral pneumonia in susceptible patients...
- POLYNUCLEOTIDE VACCINES FOR SIV INFECTION AND DISEASERobert Malone; Fiscal Year: 2000..and hence is focused on the development of such vaccines for prevention of lentiviral disease and acute viral pneumonia. Genetic immunization (DNA vaccination) and cytokine augmentation of antiviral immune responses are novel ..
- DENDRITIC CELLS, RSV AND INFLUENZA INFECTION IN CHILDRENOctavio Ramilo; Fiscal Year: 2005Respiratory syncytial virus (RSV) is the principal etiologic agent of bronchiolitis and viral pneumonia in infants and young children worldwide. Influenza viruses also contribute to significant number of hospitalizations among children...
- Mechanisms of Respiratory Syncytial Virus-Induced Mucus" Viral Strain DependenceMARTIN LAWRENCE MOORE; Fiscal Year: 2010..causes >100,000 infant hospitalizations in the US each year and is the leading cause of bronchiolitis and viral pneumonia in infants...
- HOST DEFENSE AGAINST INFLUENZAPARKER SMALL; Fiscal Year: 1990..to separate considerations of prevention and recovery as well as considerations of rhinotracheitis and viral pneumonia. Serum antibody mediates prevention of viral pneumonia, but not rhinotracheitis...
- Sixth International Respiratory Syncytial Virus SymposiumANN FALSEY; Fiscal Year: 2007..abstract_text> ..
- CCSP IN INNATE DEFENSE AGAINST LUNG VIRAL INFECTIONKEVIN HARROD; Fiscal Year: 2003..This application will determine the role and delineate mechanisms by which CCSP provides innate immunity to viral infection in the lung. Such data may be useful in designing treatment and prevention of viral pneumonia.
- Pivotal role of VLA-1 in CD8 T cell retention & survivalDavid Topham; Fiscal Year: 2007..We will also test the prediction that the VLA-1+ memory T cells are functionally distinct and important for secondary immune protection. [unreadable] [unreadable]..
- Mucosal RSV vaccine using CpG oligodeoxynucleotidesGregory Prince; Fiscal Year: 2003..Phase II activities would use that information to formulate a vaccine that would be both effective and safe. ..
- Protective Cell-Mediated Immunity Against Lethal H5N1 Influenza A VirusesPeter C Doherty; Fiscal Year: 2010..These studies should allow us to develop a clear, mechanistic understanding of how to promote effective CMI against the H5N1 viruses. ..
- Reducing Transmission of Influenza by Face MasksARNOLD MONTO; Fiscal Year: 2008..Such a reduction could have a major public health impact during a pandemic. In the second year, the study can be expanded or modified based on findings in the first. ..
- Appropriate Pneumococcal Vaccination in Infants in FijiFiona Russell; Fiscal Year: 2007..The results of this study will form the basis of an effectiveness evaluation following the pilot introduction of pneumococcal immunization into Fiji in 3-5 years time. [unreadable] [unreadable]..
- A KINETIC STUDY OF INFLAMMATION-INDUCED HYPORETINEMIAFrancisco Rosales; Fiscal Year: 2005..In addition, the application of these methods and the development of a model of chronic inflammation will foster research on other micronutrients like iron and zinc that are similarly affected by inflammation. ..
- IMPROVEMENT OF THE COTTON RAT MODEL OF HUMAN DISEASESGregory Prince; Fiscal Year: 2002..The proposed workscope of this application is to develop a library of reagents directed against cotton rat cell-surface antigens, cytokines and chemokines. ..
- Genotypes of Helicobacter Pylori in West AfricaRichard Adegbola; Fiscal Year: 2005..pylori colonization in West Africa differ from those seen in industrialized nations, and enable the development of appropriate treatment strategies for communities such as The Gambia. ..
- HAEMOPHILUS ANTIGEN REGULATION OF INFLAMMATION IN COPDSanjay Sethi; Fiscal Year: 2003..Identification of the integral bacterial and host components that contribute to immune-mediated inflammation in COPD will ultimately lead to novel therapeutic strategies to alter disease progression and improve outcome in COPD. ..
- Comparative Study of Influenza Vaccines in AdultsARNOLD MONTO; Fiscal Year: 2006..Results will help to determine how the vaccine may be used as part of the strategy to combat influenza in varying situations. [unreadable] [unreadable]..
- Mechanisms of Immune Modulation by Abscisic AcidJosep Bassaganya Riera; Fiscal Year: 2010..The mechanistic understanding of the immune modulatory properties of botanicals such as ABA will aid in the development of more efficacious CAM approaches for modulating immune function and ameliorating infectious diseases. ..
- Interaction of MHV RNA with mtHSP70 and m-aconitaseJulian Leibowitz; Fiscal Year: 2007..The functional significance of the interaction of mtHSP70, m-aconitase, HSP60, and HSP40 with MHV RNA on virus replication will be examined in a series of experiments employing mutational and over-expression strategies. ..
- Genital Ulcer Disease and HIV TransmissionJeanne Sheffield; Fiscal Year: 2005..The pursuit of these aims will further elucidate the cellular and molecular bases of the interrelationship between GUD and HIV-1 transmission, particularly in women. ..
- Genetic Determinants of A. Fumigatus SusceptibilityAimee Zaas; Fiscal Year: 2008..fumigatus infection, this proposal will identify and characterize genetic polymorphisms related to IA susceptibility in mice and validate these findings in a cohort of human bone marrow transplant donors and recipients. ..
- Regulation of the P13K/AKT pathway in Waldenstrom MacroglobulinemiaIrene Ghobrial; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Novel Model to Predict Safety and Efficacy of MicrobicidesGregory Prince; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- CYTOSKELETAL REGULATION OF ENDOTHELIAL CELL APOPTOSISIrina Petrache; Fiscal Year: 2004..abstract_text> ..
- Innate Immunity and exacerbations of COPDSanjay Sethi; Fiscal Year: 2009..The overall goal of this research is to identify specific aspects of the innate defense of the lung that determine the frequency of exacerbations in COPD that will serve as potential therapeutic targets to reduce exacerbations. ..