tick borne diseases

Summary

Summary: Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.

Top Publications

  1. ncbi Ticks and tickborne bacterial diseases in humans: an emerging infectious threat
    P Parola
    , CNRS UMR 6020, , , Marseille, France
    Clin Infect Dis 32:897-928. 2001
  2. ncbi The current status of major tick borne diseases in Zambia
    Levi Hakwale Makala
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Res 34:27-45. 2003
  3. ncbi Incidence and prevalence of tick-borne haemoparasites in domestic ruminants in Ghana
    L Bell-Sakyi
    Accra Veterinary Laboratory, Veterinary Services Department, Ministry of Food and Agriculture, PO Box M161, Accra, Ghana
    Vet Parasitol 124:25-42. 2004
  4. ncbi Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United States
    Christopher D Paddock
    Division of Viral and Rickettsial Diseases, Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Infect Dis 38:805-11. 2004
  5. pmc Tick-borne rickettsioses around the world: emerging diseases challenging old concepts
    Philippe Parola
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Universite de la Mediterranee, Faculte de Medecine, 13385 Marseille Cedex 5, France
    Clin Microbiol Rev 18:719-56. 2005
  6. ncbi Tick-borne bacterial diseases emerging in Europe
    P Parola
    , , , Marseille, France
    Clin Microbiol Infect 7:80-3. 2001
  7. ncbi Ticks feeding on humans: a review of records on human-biting Ixodoidea with special reference to pathogen transmission
    A Estrada-Pena
    Departamento de Parasitologia, Facultad de Veterinaria, Miguel Servet, Zaragoza, Spain
    Exp Appl Acarol 23:685-715. 1999
  8. pmc Tick-borne relapsing fever imported from West Africa: diagnosis by quantitative buffy coat analysis and in vitro culture of Borrelia crocidurae
    A P van Dam
    Departments of Medical Microbiology, Tropical Medicine and AIDS, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands
    J Clin Microbiol 37:2027-30. 1999
  9. pmc Coinfections acquired from ixodes ticks
    Stephen J Swanson
    Epidemic Intelligence Service Program, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Clin Microbiol Rev 19:708-27. 2006
  10. ncbi The Caribbean Amblyomma Program: some ecologic factors affecting its success
    Rupert Pegram
    FAO, Caribbean Amblyomma Program, Bridgetown, Barbados
    Ann N Y Acad Sci 1026:302-11. 2004

Detail Information

Publications240 found, 100 shown here

  1. ncbi Ticks and tickborne bacterial diseases in humans: an emerging infectious threat
    P Parola
    , CNRS UMR 6020, , , Marseille, France
    Clin Infect Dis 32:897-928. 2001
    ..Methods are described for the detection and isolation of bacteria from ticks and advice is given on how tick bites may be prevented and how clinicians should deal with patients who have been bitten by ticks...
  2. ncbi The current status of major tick borne diseases in Zambia
    Levi Hakwale Makala
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Res 34:27-45. 2003
    ..It is thus hoped that this review will stimulate the desire to maximize the value of the tick and tick-borne disease research in both Zambia and the international research community...
  3. ncbi Incidence and prevalence of tick-borne haemoparasites in domestic ruminants in Ghana
    L Bell-Sakyi
    Accra Veterinary Laboratory, Veterinary Services Department, Ministry of Food and Agriculture, PO Box M161, Accra, Ghana
    Vet Parasitol 124:25-42. 2004
    ....
  4. ncbi Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United States
    Christopher D Paddock
    Division of Viral and Rickettsial Diseases, Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Infect Dis 38:805-11. 2004
    ..parkeri rickettsiosis and possibly other novel SFG rickettsioses in the United States...
  5. pmc Tick-borne rickettsioses around the world: emerging diseases challenging old concepts
    Philippe Parola
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Universite de la Mediterranee, Faculte de Medecine, 13385 Marseille Cedex 5, France
    Clin Microbiol Rev 18:719-56. 2005
    ..We present here the tick-borne rickettsioses described through 2005 and focus on the epidemiological circumstances that have played a role in the emergence of the newly recognized diseases...
  6. ncbi Tick-borne bacterial diseases emerging in Europe
    P Parola
    , , , Marseille, France
    Clin Microbiol Infect 7:80-3. 2001
    ..burgdorferi complex and a new relapsing fever borrelia. We present these emerging diseases and focus on the factors that play a role in the recognition of new tick-borne diseases...
  7. ncbi Ticks feeding on humans: a review of records on human-biting Ixodoidea with special reference to pathogen transmission
    A Estrada-Pena
    Departamento de Parasitologia, Facultad de Veterinaria, Miguel Servet, Zaragoza, Spain
    Exp Appl Acarol 23:685-715. 1999
    ..Finally, despite the fact that most people who are bitten destroy the offending tick in disgust, it is recommended that they preserve specimens in ethanol for taxonomic identification and detection of pathogens by molecular methods...
  8. pmc Tick-borne relapsing fever imported from West Africa: diagnosis by quantitative buffy coat analysis and in vitro culture of Borrelia crocidurae
    A P van Dam
    Departments of Medical Microbiology, Tropical Medicine and AIDS, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands
    J Clin Microbiol 37:2027-30. 1999
    ..Spirochetes were also cultured from blood samples from both patients in modified Kelly's medium and were identified as B. crocidurae by partial sequencing of the PCR-amplified rrs gene...
  9. pmc Coinfections acquired from ixodes ticks
    Stephen J Swanson
    Epidemic Intelligence Service Program, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Clin Microbiol Rev 19:708-27. 2006
    ..Clinicians should consider the likelihood of coinfection when pursuing laboratory testing or selecting therapy for patients with tick-borne illness...
  10. ncbi The Caribbean Amblyomma Program: some ecologic factors affecting its success
    Rupert Pegram
    FAO, Caribbean Amblyomma Program, Bridgetown, Barbados
    Ann N Y Acad Sci 1026:302-11. 2004
    ..Thus, feral or free-ranging livestock were rarely a problem in these islands. These differences in land use management are compared and discussed in relation to their perceived profound impact on TBT eradication efforts in the region...
  11. ncbi RNA interference for the study and genetic manipulation of ticks
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Trends Parasitol 23:427-33. 2007
    ..It is probable that the knowledge gained from this experimental approach will contribute to development of vaccines to control tick infestations and the transmission of tick-borne pathogens...
  12. ncbi Tick cell lines: tools for tick and tick-borne disease research
    Lesley Bell-Sakyi
    Centre for Tropical Veterinary Medicine, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK
    Trends Parasitol 23:450-7. 2007
    ....
  13. ncbi Guidelines for the diagnosis of tick-borne bacterial diseases in Europe
    P Brouqui
    Unite des Rickettsies, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Clin Microbiol Infect 10:1108-32. 2004
    ..These guidelines aim to help clinicians and microbiologists in diagnosing infection transmitted by tick bites and to provide the scientific and medical community with a better understanding of these infectious diseases...
  14. pmc Kinetics of antibody responses in Rickettsia africae and Rickettsia conorii infections
    Pierre Edouard Fournier
    Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Clin Diagn Lab Immunol 9:324-8. 2002
    ..We recommend that sera collected 4 weeks after the onset of signs of patients with suspected African tick-bite fever should be used for the definitive serological diagnosis of R. africae infections...
  15. pmc Imported tickborne relapsing fever, France
    Benjamin Wyplosz
    Emerg Infect Dis 11:1801-3. 2005
  16. ncbi Spotless rickettsiosis caused by Rickettsia slovaca and associated with Dermacentor ticks
    Didier Raoult
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Clin Infect Dis 34:1331-6. 2002
    ..Immunofluorescence and/or Western blot analysis detected antibodies in 50% of tested patients. Three Dermacentor ticks obtained from patients revealed R. slovaca by PCR...
  17. ncbi Imported spotted fever rickettsioses in United States travelers returning from Africa: a summary of cases confirmed by laboratory testing at the Centers for Disease Control and Prevention, 1999-2002
    Jennifer H McQuiston
    Viral and Rickettsial Zoonoses Branch, and Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Disease, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 70:98-101. 2004
    ....
  18. ncbi Dermacentor-borne necrosis erythema and lymphadenopathy: clinical and epidemiological features of a new tick-borne disease
    J A Oteo
    Servicio de Medicina Interna y Enfermedades Infecciosas, Hospital de La Rioja, Logrono, Spain
    Clin Microbiol Infect 10:327-31. 2004
    ..The probable aetiological agent is Rickettsia slovaca. Similar cases have been reported in other European countries...
  19. ncbi The Ixodes scapularis Genome Project: an opportunity for advancing tick research
    Catherine A Hill
    Department of Entomology, Purdue University, West Lafayette, IN 47907, USA
    Trends Parasitol 21:151-3. 2005
    ..The IGP will be the first genomic analysis of a member of the subphylum Chelicerata and will accelerate the pace of tick research. The challenge for scientists is to translate IGP data into public health benefits...
  20. pmc Detection of Borrelia lonestari, putative agent of southern tick-associated rash illness, in white-tailed deer (Odocoileus virginianus) from the southeastern United States
    Victor A Moore
    Department of Medical Microbiology and Parasitology Southeastern Cooperative Wildlife Disease Study, College of Veterinary Medicine The D B Warnell School of Forest Resources, The University of Georgia, Athens, Georgia 30602
    J Clin Microbiol 41:424-7. 2003
    ..lonestari or another closely related Borrelia species. Our findings expand the known geographic range of B. lonestari and provide the first evidence of this organism in a vertebrate other than humans...
  21. pmc Investigation of tick-borne viruses as pathogens of humans in South Africa and evidence of Dugbe virus infection in a patient with prolonged thrombocytopenia
    F J Burt
    Department of Virology, University of the Witwatersrand, Johannesburg, South Africa
    Epidemiol Infect 116:353-61. 1996
    ..The latter patient suffered from febrile illness with prolonged thrombocytopenia...
  22. pmc Detection of a rickettsia closely related to Rickettsia aeschlimannii, "Rickettsia heilongjiangensis," Rickettsia sp. strain RpA4, and Ehrlichia muris in ticks collected in Russia and Kazakhstan
    Stanislav Shpynov
    Unite des Rickettsies, IFR48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 5, France
    J Clin Microbiol 42:2221-3. 2004
    ..In Kazakhstan, we detected Rickettsia sp. strain RpA4 and a rickettsia closely related to Rickettsia aeschlimannii. These agents should be considered in a differential diagnosis of tick-borne infections in these areas...
  23. ncbi [Ticks and human tick-borne diseases in Africa]
    C Socolovschi
    Centre Collaborateur OMS pour les rickettsioses et les maladies bactériennes vectorisées, Faculte de Medecine, Marseille
    Med Trop (Mars) 68:119-33. 2008
    ..The next part of the article describes the main human tick borne diseases in Africa with particular focus on spotted fever group rickettsioses, relapsing fever borrelioses, and ..
  24. ncbi African tick bite fever
    Mogens Jensenius
    Department of Internal Medicine, Aker University Hospital, Oslo, Norway
    Lancet Infect Dis 3:557-64. 2003
    ..Travellers to endemic areas should be informed of the risk of contracting African tick bite fever and be encouraged to take personal protective measures against tick bites...
  25. ncbi Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis--United States: a practical guide for physicians and other health-care and public health professionals
    Alice S Chapman
    National Center for Infectious Diseases, CDC, Atlanta, GA 30333, USA
    MMWR Recomm Rep 55:1-27. 2006
    ....
  26. ncbi Detection of relapsing fever in human blood samples from Israel using PCR targeting the glycerophosphodiester phosphodiesterase (GlpQ) gene
    Tamar Halperin
    Center for Infectious Disease Research, Medical Corps, IDF, M P O Box 02149, Israel
    Acta Trop 98:189-95. 2006
    ..A second modified GlpQ PCR was able to discriminate between probable B. persica and B. recurrentis and B. crocidurae infection. This study describes the first molecular assay for the diagnosis of relapsing fever caused by B. persica...
  27. ncbi African tick bite fever in travelers to rural sub-Equatorial Africa
    Mogens Jensenius
    Department of Internal Medicine, Aker University Hospital, Oslo, Norway
    Clin Infect Dis 36:1411-7. 2003
    ..Our study suggests that ATBF is not uncommon in travelers to rural sub-Saharan Africa and that many cases have a nonspecific presentation...
  28. ncbi RNA interference screening in ticks for identification of protective antigens
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Parasitol Res 96:137-41. 2005
    ....
  29. pmc Histologic features and immunodetection of African tick-bite fever eschar
    Hubert Lepidi
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 12:1332-7. 2006
    ..Neutrophils in ATBF are a notable component of the host reaction, perhaps because ATBF is a milder disease than the other rickettsioses. Immunohistochemical detection of rickettsial antigens may be useful in diagnosing ATBF...
  30. ncbi Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa
    D Raoult
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseilles, France
    N Engl J Med 344:1504-10. 2001
    ..African tick-bite fever occurs after contact with ticks that carry Rickettsia africae and that parasitize cattle and game. Sporadic reports suggest that this infection has specific clinical and epidemiologic features...
  31. ncbi Tick-borne lymphadenopathy (TIBOLA)
    Andras Lakos
    Centre for Tick borne Diseases, Budapest, Hungary
    Wien Klin Wochenschr 114:648-54. 2002
    ..From 1996 through 2000, we collected data on 86 patients with similar symptoms following a tick bite. The inclusion criteria were: enlarged regional lymph nodes and/or vesicular-ulcerative local reaction at the site of the tick bite...
  32. pmc Comparison of immunofluorescence, Western blotting, and cross-adsorption assays for diagnosis of African tick bite fever
    Mogens Jensenius
    Department of Internal Medicine, Aker University Hospital, Oslo, Norway
    Clin Diagn Lab Immunol 11:786-8. 2004
    ..01). A specific diagnosis of Rickettsia africae infection could be established in 15% of the patients by IFA and in 73% of the patients by a combination of WB and cross-adsorption assays (P < 0.01)...
  33. ncbi A new rickettsial disease in the United States
    Didier Raoult
    Clin Infect Dis 38:812-3. 2004
  34. ncbi Successful in vitro cultivation of Borrelia duttonii and its comparison with Borrelia recurrentis
    S J Cutler
    Imperial College School of Medicine Infectious Diseases and Medical Microbiology, Charing Cross Campus, London, UK
    Int J Syst Bacteriol 49:1793-9. 1999
    ..7% homology with three strains deposited by others in GenBank. The rrs gene of eight representative clinical isolates of B. recurrentis confirmed their close similarity with B. duttonii...
  35. pmc Typing African relapsing fever spirochetes
    Julie Christine Scott
    Department of Cellular and Molecular Biology, Imperial College of Science, Technology and Medicine, South Kensington, London, United Kingdom
    Emerg Infect Dis 11:1722-9. 2005
    ..and a unique clade, distant from those associated with relapsing fever, possibly equivalent to a novel species in ticks from this region. Clinical significance of this spirochete is undetermined...
  36. ncbi Advances in the genomics of ticks and tick-borne pathogens
    Frans Jongejan
    Trends Parasitol 23:391-6. 2007
    ..Each advance reveals new levels of complexity, but there are encouraging signs that genomics is leading to novel means of parasite control...
  37. ncbi Tick-borne diseases of livestock in Italy: general review and results of recent studies carried out in the Apulia region
    L Ceci
    Dipartimento di Sanita, Patologia, Farmaco Tossicologia e Benessere degli Animali, Facolta di Medicina Veterinaria, Universita di Bari, Valenzano, Italy
    Parassitologia 41:25-9. 1999
    ..In another study in the same region a microscopic prevalence of 78% for Theileria spp. was found in 60 cows. Afterwards using the IFAT test the Theileria sp. was identified as Theileria buffeli/orientalis...
  38. ncbi Integrated control of ticks and tick-borne diseases
    F Jongejan
    Department of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Parassitologia 41:57-8. 1999
    ..This paper gives a brief overview of the ICTTD project activities against the background of recent initiatives to assess the impact of ticks and tick-borne diseases in the Mediterranean region...
  39. pmc African tick-bite fever in French travelers
    Paul H Consigny
    Emerg Infect Dis 11:1804-6. 2005
  40. ncbi Diagnostics of tick-borne diseases in the endemic region of Russia
    Natalia N Vorobyeva
    Perm Medical Academy, Perm, Russia
    Wien Klin Wochenschr 114:610-2. 2002
    ..The specific characteristics of human monocytic ehrlichiosis include nervous impairments, hepatic lesions, the frequent development of a two-wave course and hemogram changes...
  41. ncbi African tick bite fever: not a spotless rickettsiosis!
    Laurence Toutous-Trellu
    Dermatology Department, Geneva University Hospital, Geneve, Switzerland
    J Am Acad Dermatol 48:S18-9. 2003
    ..We report the case of a patient with an unusual site of a tick bite and discuss cutaneous differences from other spotted fevers that may help dermatologists with clinical diagnosis...
  42. ncbi African tick-bite fever: four cases among Swiss travelers returning from South Africa
    Yves Jackson
    Unit of Travel and Migration Medicine, Department of Community Medicine, University Hospital Geneva, Geneva, Switzerland
    J Travel Med 11:225-8. 2004
    ..African tick-bite fever (ATBF) is a recently described disease belonging to the spotted fever group. It is caused by Rickettsia africae, and cases are mainly diagnosed in travelers returning from sub-Saharan Africa...
  43. ncbi Tick-borne rickettsioses in international travellers
    Mogens Jensenius
    Department of Internal Medicine, Aker University Hospital, Oslo, Norway
    Int J Infect Dis 8:139-46. 2004
    ..We describe the current knowledge of tick-borne rickettsioses as they relate to international travel, their microbiological diagnosis, treatment, possible prevention, and future prospects...
  44. ncbi [Ticks and the pediatrician]
    P Occorsio
    A O R N Santobono Pausilipon III Pediatria, P O Santobono Napoli
    Parassitologia 46:115-8. 2004
    ....
  45. ncbi Risk of Borrelia burgdorferi infection in western Switzerland following a tick bite
    I Nahimana
    Division de Médecine Préventive Hospitalière, CHUV, 1011 Lausanne, Switzerland
    Eur J Clin Microbiol Infect Dis 23:603-8. 2004
    ..In conclusion, the risk of developing Lyme borreliosis in western Switzerland after a tick bite is low, and therefore, prophylactic antibiotics are not required...
  46. ncbi [Tick-transmitted diseases which may threaten health of dogs in Poland]
    Wojciech Zygner
    Zakład Parazytologii i Inwazjologii, Katedra Nauk Przedklinicznych, Wydział Medycyny Weterynaryjnej SGGW, ul Ciszewskiego 8, 02 786 Warszawa
    Wiad Parazytol 52:85-92. 2006
    ..Tick-borne diseases can result from infection with bacteria, viruses and parasitic protozoa. In this review we present most important tick-transmitted diseases which may occur in dogs in Poland...
  47. ncbi [Tick borne zoonosis: selected clinical and diagnostic aspects]
    V Sambri
    Sezione di Microbiologia, DMCSS, Universita di Bologna, Policlinico S Orsola Malpighi, Via Massarenti 9, 40138 Bologna
    Parassitologia 46:109-13. 2004
    ..Serology is anyway the main laboratory tool to perform this diagnosis. Complement fixation and EIA IgM are the most used methods: the latter technique is particularly sensitive in early infection...
  48. ncbi [Ticks (Acarina: Ixodidae) as vectors and reservoirs of pathogen microorganisms in Spain]
    Francisco José Márquez-Jiménez
    Departamento de Biologia Animal, Biología Vegetal y Ecología, Facultad de Ciencias Experimentales, Universidad de Jaen, Campus Las Lagunillas s n, 23071 Jaen, Spain
    Enferm Infecc Microbiol Clin 23:94-102. 2005
    ..conorii, R. slovaca, R. aeschlimannii) and Anaplasma phagocytophila...
  49. ncbi [Ixodes ricinus, transmitted diseases and reservoirs]
    A Rizzoli
    Centro di Ecologia Alpina, Viote del Monte Bondone, 38040, Trento, Italy
    Parassitologia 46:119-22. 2004
    ..l. in the vast majority of the areas classified as suitable for I. ricinus occurrence in Trentino, while the condition for TBE persistence appeared to be more restricted by a combination of climatic condition and host densities...
  50. ncbi Serologic and molecular characterization of tickborne pathogens in lions (Panthera leo) from the Fasano Safari Park, Italy
    Alessandra Torina
    Istituto Zooprofilattico Sperimentale della Sicilia, Sicily, Italy
    J Zoo Wildl Med 38:591-3. 2007
    ..This study is the first report of molecular evidence of infection with C. burnetii, Rickettsia sp., and A. phagocytophilum in lions and provides evidence that these felids become infected and serve as hosts for tick-transmitted bacteria...
  51. ncbi Spotted fever group rickettsioses in Himachal Pradesh
    S K Mahajan
    Department of Medicine, IG Medical College, Shimla, India
    J Assoc Physicians India 55:868-70. 2007
    ..We present two cases of SFG rickettsioses; from the northern hilly region of India that were confirmed using specific microimmunofluorescence assay...
  52. ncbi [Rickettsia africae, the agent of African tick-bite fever: an emerging pathogen in the West Indies and Reunion Island (Indian Ocean)]
    P Parola
    Unité des Rickettsies et pathogènes émergents, CNRS UMR 6020, Faculte de Medecine, Marseille 5, France
    Bull Soc Pathol Exot 97:193-8. 2004
    ..africae...
  53. ncbi Rickettsia aeschlimannii in Hyalomma ticks from Corsica
    K Matsumoto
    Unite des Rickettsies, Faculte de Medecine, WHO Collaborative Center for Rickettsial Reference and Research, CNRS UMR 6020 IFR 48, 27 Bd Jean Moulin, Marseille Cedex 5, France
    Eur J Clin Microbiol Infect Dis 23:732-4. 2004
  54. ncbi Tick-borne bacterial, rickettsial, spirochetal, and protozoal infectious diseases in the United States: a comprehensive review
    Jarrett R Amsden
    Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Pharmacotherapy 25:191-210. 2005
    ..Because pharmacists are the most accessible health care providers, they are often asked how to treat tick-borne diseases. Thus, practitioners should be familiar with the ticks that inhabit their locale...
  55. ncbi [Clinical and epidemiological study of spotted fever group rickettsiosis in Albacete, Spain]
    Joaquín Bartolomé
    Laboratorio de Microbiologia, Complejo Hospitalario Universitario de Albacete, Espana
    Enferm Infecc Microbiol Clin 23:194-6. 2005
    ..The aim of this study was to describe the clinical and epidemiological features of spotted fever group rickettsiosis acquired in the province of Albacete, Spain...
  56. pmc Tick species and tick-borne infections identified in population from a rural area of Spain
    Francisco Jesús Merino
    Servicio de Microbiologia, Hospital Santa Barbara, Complejo Hospitalario de Soria, Soria, Spain
    Epidemiol Infect 133:943-9. 2005
    ..11 Rickettsia slovaca, 6 Rickettsia spp. RpA4/DnS14, 1 Rickettsia massiliae/Bar29, and 8 unidentified); two ticks carried DNA from Borrelia burgdorferi sensu lato and seven ticks harboured DNA from Anaplasma phagocytophilum...
  57. pmc Cardiac involvement in a patient with clinical and serological evidence of African tick-bite fever
    Cristina Bellini
    Infectious Diseases Unit, University Hospital of Lausanne, Lausanne, Switzerland
    BMC Infect Dis 5:90. 2005
    ..conorii. African tick-bite fever (ATBF) is generally considered as a benign disease and no cases of myocardial involvement due to Rickettsia africae, the agent of ATBF, have yet been described...
  58. ncbi Current status of ticks in Asia
    Jabbar Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S159-62. 2007
    ..Besides the knowledge dissemination, this meeting resulted in a number of achievements such as the establishment of working groups for epidemiological studies and distribution of tick differentiation protocols and diagnostic tools...
  59. ncbi Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessity
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Trends Parasitol 23:420-6. 2007
    ..As a result, there is a continuing necessity to use available live vaccines in tick and tick-borne disease-control strategies adapted to conditions prevailing in many parts of the world...
  60. ncbi [Diagnostics of human granulocytic anaplasmosis]
    Anna Grzeszczuk
    Klinika Obserwacyjno Zakaźna, Akademia Medyczna, ul Zurawia 14, 15 540 Białystok
    Wiad Parazytol 51:109-14. 2005
    ....
  61. ncbi Using genomic approaches to unravel livestock (host)-tick-pathogen interactions
    Kirsty Jensen
    Division of Genetics and Genomics, Roslin Institute, Roslin, Midlothian, Edinburgh, EH25 9PS, UK
    Trends Parasitol 23:439-44. 2007
    ....
  62. ncbi Acaricidal and repellent properties of permethrin, its role in reducing transmission of vector-borne pathogens
    N Mencke
    Bayer HealthCare AG, Animal Health Division, Leverkusen, Germany
    Parassitologia 48:139-40. 2006
    ..To achieve this, acaricides with repellent properties, such as the synthetic pyrethroid permethrin are ideal compounds to reach this goal...
  63. ncbi Tick control: further thoughts on a research agenda
    Daniel E Sonenshine
    Department of Biological Sciences, Old Dominion University, Norfolk, VA 23529, USA
    Trends Parasitol 22:550-1. 2006
    ....
  64. ncbi [Rickettsia slovaca infection alter a tick bite]
    P J Alcalá Minagorre
    An Pediatr (Barc) 65:386-7. 2006
  65. ncbi Prevalence of and risk factors for canine tick infestation in the United States, 2002-2004
    Malathi Raghavan
    Department of Veterinary Pathobiology, Purdue University, West Lafayette, Indiana, USA
    Vector Borne Zoonotic Dis 7:65-75. 2007
    ..Feasibility of collecting information for surveillance of vectors ticks on a national level using this large, electronic veterinary database is discussed...
  66. ncbi Ticks of small ruminants in China
    Hong Yin
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, PR China
    Parasitol Res 101:S187-9. 2007
    ..Haemaphysalis qinghaiensis transmits the two as yet unidentified species of Theileria transstadially. Priorities for future research on these diseases are summarised...
  67. ncbi Status of tick distribution in Bangladesh, India and Pakistan
    Srikant Ghosh
    Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, India
    Parasitol Res 101:S207-16. 2007
    ..Among the parasitological problems, the damage caused by TTBDs is considered very high, and the control of TTBDs has been given priority...
  68. ncbi Detection of Rickettsia amblyommii in association with a tick bite rash
    Sarah A Billeter
    Vector Borne Diagnostic Disease Laboratory, North Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina 27606, USA
    Vector Borne Zoonotic Dis 7:607-10. 2007
    ..amblyommii" by sequencing. To our knowledge, this is the first case in which R. amblyommii was temporally associated with a rash...
  69. ncbi [Study on the coinfection of three tick-borne infectious diseases in China using polymerase chain reaction method]
    Qiu Min Zhao
    Institute of Microbiology and Epidemiology, Academy of Military Medical Science, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 26:9-13. 2005
    ..To study the existence of Ehrluichiosis, lyme disease and tick-borne spotted fever coinfection in some areas in China...
  70. ncbi Ticks and tick-borne disease in Guatemalan cattle and horses
    Mike Teglas
    Center for Vectorborne Diseases, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Parasitol 131:119-27. 2005
    ..Prevalence of infection, tick infestation levels, host factors and environmental data were analyzed for association; A. nitens was significantly associated with A. phagocytophilum prevalence by village...
  71. ncbi The global importance of ticks
    F Jongejan
    Department of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, PO Box 80 165, 3508 TD Utrecht, The Netherlands
    Parasitology 129:S3-14. 2004
    ..The impact of ticks and tick-borne diseases on animal production and public health and their control are discussed...
  72. ncbi Tick-host interactions: saliva-activated transmission
    P A Nuttall
    Centre for Ecology and Hydrology, Mansfield Rd, Oxford, OX1 3SR, UK
    Parasitology 129:S177-89. 2004
    ..Whatever they turn out to be, the quest to identify the tick molecules that mediate SAT is an exciting one, and offers new insights to controlling ticks and tick-borne diseases...
  73. ncbi Chemical control of ticks on cattle and the resistance of these parasites to acaricides
    J E George
    Knipling Bushland US Livestock Insects Research Laboratory, USDA, Agricultural Research Service, 2700 Fredericksburg Road, Kerrville, Texas 78028 9184, USA
    Parasitology 129:S353-66. 2004
    ..There is a need to transfer knowledge about tick control and resistance mitigation strategies to cattle producers...
  74. ncbi Biological control of ticks
    M Samish
    Dept of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Parasitology 129:S389-403. 2004
    ..Considerable research is required to select appropriate strains, develop them as BCAs, establish their effectiveness, and devise production strategies to bring them to practical use...
  75. ncbi Tick immunobiology
    M Brossard
    Institute of Zoology, University of Neuchatel, Emile Argand 11, CH 2007, Neuchatel, Switzerland
    Parasitology 129:S161-76. 2004
    ....
  76. ncbi Observed prevalence of tick-borne pathogens in domestic animals in Sicily, Italy during 2003-2005
    A Torina
    Instituto Zooprofilattico Sperimentale della Sicilia, Via G Marinuzzi no 3, 90129 Palermo, Sicily, Italy
    Zoonoses Public Health 54:8-15. 2007
    ....
  77. ncbi Tick-borne infections in children: epidemiology, clinical manifestations, and optimal management strategies
    Steven C Buckingham
    Department of Pediatrics, Division of Infectious Disease, University of Tennessee Health Science Center and Children s Foundation Research Center at Le Bonheur Children s Medical Center, Memphis, Tennessee, USA
    Paediatr Drugs 7:163-76. 2005
    ..The role of antiviral therapy in the treatment of other tick-borne viral infections, including other hemorrhagic fevers and tick-borne encephalitis, is not yet defined...
  78. ncbi Methods of isolation and cultivation of new Rickettsiae from the Nosoarea of the north Asian tick typhus in Siberia
    I E Samoylenko
    Omsk Research Institute of Natural Foci Infections, 644080, Prospekt Mira, 7 Omsk, Russia
    Ann N Y Acad Sci 1078:613-6. 2006
  79. ncbi Tick saliva in anti-tick immunity and pathogen transmission
    L Kovar
    Institute of Microbiology, Academy of Sciences of the Czech Republic, 142 20 Prague, Czechia
    Folia Microbiol (Praha) 49:327-36. 2004
    ..Many pharmacological properties of saliva described in ticks are shared widely among other blood-feeding arthropods...
  80. ncbi Tick-borne rickettsial diseases: emerging risks in Europe
    Philippe Parola
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Universite de la Mediterranee, Faculte de Medecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France
    Comp Immunol Microbiol Infect Dis 27:297-304. 2004
    ..We present here these emerging diseases and discuss other potential threat for the future...
  81. ncbi African tick-bite fever in South Africa
    Janice Taverne
    Trends Parasitol 18:292. 2002
  82. ncbi Tick-borne diseases: tick-borne spotted fever rickettsioses in Africa
    Cecile Cazorla
    Service de Medecine Interne et Maladies Infectieuses, Centre Hospitalier Territorial de Nouvelle Calédonie, BP J 5, 98849 Nouméa cedex, France
    Infect Dis Clin North Am 22:531-44, ix-x. 2008
    ..africae, seven distinct species of tick-borne rickettsiae are considered to be human pathogens. A combination of clinical alertness and molecular tools such as PCR base detection of DNA and sequencing help to describe new diseases...
  83. ncbi Exposed and concealed antigens as vaccine targets for controlling ticks and tick-borne diseases
    P A Nuttall
    Centre for Ecology and Hydrology, Oxford, UK
    Parasite Immunol 28:155-63. 2006
    ..With the proliferation of molecular techniques and their application to vaccine development, there are high hopes for new and effective antitick vaccines that also control tick-borne diseases...
  84. ncbi Detection, characterization, and prediction of tick-borne disease foci
    M Roberto Cortinas
    College of Veterinary Medicine, University of Illinois, Urbana 61802, USA
    Int J Med Microbiol 291:11-20. 2002
    ..The process of introduction and establishment of new tick foci along the Illinois River is described in relation to the known tick distribution and predictions of invasion based on the risk model...
  85. ncbi Risk of tick-borne bacterial diseases in humans in the Florence area, Tuscany
    Lorenzo Ciceroni
    Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanita, 00161 Rome, Italy
    Ann N Y Acad Sci 990:346-9. 2003
  86. ncbi [Ticks--due to climatic changes, much more than just Ixodes ricinus, TBE and Lyme disease]
    Thomas F Voigt
    Med Monatsschr Pharm 31:240-6. 2008
    ..Climatic as well as microclimatic conditions play a major role. Against this background, it can be anticipated that climatic changes also influence the bionomics of ticks and of the pathogens conferred by them...
  87. ncbi Etiology of tick-borne febrile illnesses in Slovenian children
    Maja Arnez
    Department of Infectious Diseases, University Medical Centre Ljubljana, 1525 Ljubljana, Slovenia
    Ann N Y Acad Sci 990:353-4. 2003
  88. ncbi Ticks and tick-related illness
    Jerome M Larkin
    Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, USA
    Med Health R I 91:209-11. 2008
  89. ncbi Dermatoses from ticks
    Daniel E McGinley-Smith
    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    J Am Acad Dermatol 49:363-92; quiz 393-6. 2003
    ..The epidemiology, clinical features, diagnosis, and treatment of these diseases are reviewed with an emphasis on cutaneous manifestations. Finally, the prevention of diseases caused by ticks is reviewed...
  90. ncbi Tick-borne parasitic diseases in cattle: current knowledge and prospective risk analysis related to the ongoing evolution in French cattle farming systems
    Monique L'hostis
    UMR ENVN INRA 1034 Interactions Hĵte Parasite Milieu, Ecole Nationale Veterinaire de Nantes, France
    Vet Res 33:599-611. 2002
    ..This results in likely modifications of the endemic situation, with a higher risk of clinical babesiosis in the medium term...
  91. ncbi Detection of haemoparasites in cattle by reverse line blot hybridisation with a note on the distribution of ticks in Sicily
    K Georges
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands
    Vet Parasitol 99:273-86. 2001
    ..lusitanicum, Rhipicephalus sanguineus group, R. bursa, Dermacentor marginatus, Haemaphysalis punctata, B. annulatus and I. ricinus...
  92. ncbi Aponomma hydrosauri, the reptile-associated tick reservoir of Rickettsia honei on Flinders Island, Australia
    John Stenos
    Australian Rickettsial Reference Laboratory, The Geelong Hospital, Geelong, Victoria, Australia
    Am J Trop Med Hyg 69:314-7. 2003
    ..From the positive tick samples, seven were sequenced and found to be 100% homologous with R. honei. Of 17 reptiles examined, none had evidence of rickettsiae by PCR or culture of blood...
  93. ncbi [Climate change influences the incidence of arthropod-borne diseases in the Netherlands]
    J C Rahamat-Langendoen
    Rijksinstituut voor Volksgezondheid en Milieu, Centrum Infectieziektebestrijding, afd Epidemiologie en Surveillance, Postbak 75, Postbus I, 3720 BA Bilthoven
    Ned Tijdschr Geneeskd 152:863-8. 2008
    ..g. West Nile virus, Dengue virus, Leishmania) is not clear. Continued vigilance is necessary, even for vector-borne diseases that appear to be less relevant for the Netherlands...
  94. ncbi Systemic inflammatory responses in African tick-bite fever
    Mogens Jensenius
    Department of Internal Medicine, Aker University Hospital, Oslo, Norway
    J Infect Dis 187:1332-6. 2003
    ..The induction of these mediators and the balance between them may be critical both for the regulation of inflammation and for protective immunity in ATBF...
  95. ncbi Epidemiological and clinical differences among Rickettsia slovaca rickettsiosis and other tick-borne diseases in Spain
    Jose A Oteo
    Servicio de Enfermedades Infecciosas, Hospital de La Rioja, 26001 Logroño, Spain
    Ann N Y Acad Sci 990:355-6. 2003
  96. ncbi [Tick-borne human pathogenic microorganisms found in Europe and those considered nonpathogenic. Part II: Bacteria, parasites and mixed infections]
    J Süss
    Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Standort, Jena
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:470-86. 2004
    ..In general one can say that considerable additional scientific research is necessary to effectively reduce the incidence of tick-borne diseases...
  97. ncbi Retrospective seroepidemiological survey for human babesiosis in an area in Japan where a tick-borne disease is endemic
    Satoru Arai
    Infectious Disease Surveillance Center, Tokyo, Japan
    J Vet Med Sci 65:335-40. 2003
    ..S.-type parasite has not been found in Japan. Our results suggest that human babesiosis in Japan occurred prior to the discovery of the index case in 1999 and that the infections were caused mainly by Hobetsu-type parasites...
  98. ncbi Tick-borne diseases in ruminants of Central and Southern Italy: epidemiology and case reports
    G Savini
    Istituto Zooprofilattico Sperimentale dell Abruzzo e Molise G Caporale, Teramo, Italy
    Parassitologia 41:95-100. 1999
    ..bovis (18% within herd), 10% for Babesia ovis (19% within herd), 10% for B. motasi (17.5% within herd), 63% for Theileria in cattle (66% within herd) and 51% for Theileria in sheep (55% within herd)...
  99. ncbi Relationship between tick bites and the seroprevalence of Babesia microti and Anaplasma phagocytophila (previously Ehrlichia sp.) in blood donors
    David A Leiby
    Transmissible Diseases Department, American Red Cross, Rockville, MD 20855, USA
    Transfusion 42:1585-91. 2002
    ..Despite an increased recognition of the threat tick-borne agents pose to blood safety, our understanding of the prevalence and transmissibility of these agents in blood donors is limited...
  100. ncbi Foci of tick-borne diseases in southwest Germany
    Rainer Oehme
    State Health Office Baden Wuerttemberg, Stuttgart, Germany
    Int J Med Microbiol 291:22-9. 2002
    ..Vaccination against TBE-virus should not only be recommended for high endemic areas but also for persons with a high individual risk...
  101. ncbi Tick-borne disease agents in various wildlife from Mississippi
    Ashley H Castellaw
    Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA
    Vector Borne Zoonotic Dis 11:439-42. 2011
    ..Thus, in general, these four wildlife species are exposed to tick-borne disease agents in Mississippi, suggesting that ticks carry and have the potential to transmit the agents to humans in the state...

Research Grants43

  1. Systematics of medically important Dermacentor tick vectors
    Dmitry A Apanaskevich; Fiscal Year: 2011
    ....
  2. Translational Immunology Research and Accelerated [vaccine] Development (TRIAD)
    ANNE SEARLS DEGROOT; Fiscal Year: 2013
    ..pylori, tick borne diseases) as the focal point of this proposal...
  3. Symbiotic Rickettsia Species as a Model System for the Study of Folate Biosynthes
    Jianmin Zhong; Fiscal Year: 2012
    ..The proposed studies will offer an ideal model system to study the impact of bacterial endosymbionts on the metabolism of ticks and more specifically, the effect of the Rickettsia endosymbiont on Ixodes pacificus fitness. ..
  4. Tick feeding regulation by orthologous tick saliva serine protease inhibitors
    Albert Mulenga; Fiscal Year: 2013
    ..The importance of white tailed deer (Odocoileus virginianus) in the emergence of major human tick borne diseases (TBD) in the United States, Lyme disease, human anaplasmosis, babesiosis and ehrlichiosis and the southern ..
  5. Development of a multivalent vaccine for mouse reservoirs of deer tick pathogens
    Linden T Hu; Fiscal Year: 2010
    ..us to develop a multivalent vaccine containing both tick and pathogen antigens for improved reduction of tick borne diseases in reservoir animals...
  6. Identification of bacterial genes required for transmission of tick-borne pathoge
    Susan M Noh; Fiscal Year: 2012
    ..The objective of this research is to identify how bacterial pathogens colonize the tick, with the long-term goal of developing new means of preventing tick colonization, and thus preventing tick-borne disease. ..
  7. Molecular basis for spotted fever group Rickettsia vector competence in ticks
    Kevin R Macaluso; Fiscal Year: 2013
    ....
  8. Molecular Mechanisms Regulating Early Stage Tick Feeding
    Albert Mulenga; Fiscal Year: 2012
    ..Identification of important tick proteins that regulate tick physiology and facilitate tick feeding is important before alternative tick control methods can be developed. ..
  9. Vector Surveillance Ontology and Vector Management Ontology
    Saul Lozano Fuentes; Fiscal Year: 2010
    ..Moore, Marlize Coleman and Sanika Chitari) with broad expertise in Information Systems / Decision Support Systems and mosquito- and tick-borne diseases. ..
  10. Culture and Identification of Rickettsia-like Organisms in Maryland
    Douglas E Norris; Fiscal Year: 2010
    ..Additionally, we will utilize the genetic material recovered via culture, to develop, optimize and utilize molecular methods to characterize these novel organisms that have eluded identification with existing tools. ..
  11. Role of Vector antioxidant factors in Amblyomma-Rickettsia interaction
    Shahid Karim; Fiscal Year: 2012
    ..The proposed research is relevant to protecting public health because understanding spotted fever group rickettsia transmission could enhance research aimed at blocking Rickettsial transmission. ..
  12. Relapsing fever spirochete protein production within the vector
    Job E Lopez; Fiscal Year: 2013
    ..The results will also direct vaccine development against RF spirochetes, targeting bacterial Omps produced within the salivary glands, consequently neutralizing the bacteria as they enter the host. ..
  13. Vector and Host Contributions to the Regulation of E. chaffeensis Gene Expression
    Roman R Ganta; Fiscal Year: 2013
    ..chaffeensis in vivo growth, and 3) perform mutational analysis and in vivo screening to identify additional genes essential for the E. chaffeensis pathogenesis in vertebrate and tick hosts. ..
  14. 13th International Conference on Lyme Borreliosis and Other Tick-borne Diseases
    Linden T Hu; Fiscal Year: 2013
    ..Participation from traditionally underrepresented minority groups will be actively solicited. ..
  15. Signaling pathways for tick salivary secretion
    Yoonseong Park; Fiscal Year: 2013
    ..The fundamental knowledge will offer rational approaches to the development of environmentally benign acaricidal compounds. ..
  16. CRITICAL ROLE OF THE ASC/CASPASE-1 PATHWAY IN TICK-BORNE RICKETTSIOSES
    JOAO PEDRA; Fiscal Year: 2009
    ..To accomplish these goals, Dr. Pedra will have free access to the modern facilities present at Yale University and will make use of the most current techniques available in immunobiology, microbial pathogenesis and proteomics. ..
  17. Rickettsia ricketti and Rickettsia-like organisms in Maryland
    Douglas Norris; Fiscal Year: 2009
    ..2. Identify and characterize Rickettsia and Rickettsia-like NIAID Priority Pathogens infecting man-biting ticks of Maryland. ..
  18. Preventing exposure to ticks and tick-borne illness in outdoor workers
    STEVEN RICHARD MESHNICK; Fiscal Year: 2013
    ..Possible clothing-related adverse events, such as rashes, will be recorded. The results of this study could lead to a simple and cost-effective method of protecting outdoor workers from tick-borne illnesses. ..
  19. Coinfection of Tick-borne Diseases in Areas of Wisconsin
    DIANE CAPORALE; Fiscal Year: 2001
    ..If this strain is prevalent in this state, vaccine developers should investigate the efficacy of their vaccine on this strain. ..
  20. Spatially-explicit mathematical model of human monocytic ehrlichiosis
    HOLLY GAFF; Fiscal Year: 2010
    ..Additionally, the analysis of the model will provide guidance for more effective treatment strategies to hopefully reduce the numbers of HME cases. ..
  21. NOVEL ANTIGENS FOR THE SERODIAGNOSIS OF HUMAN BABESIOSIS
    Raymond Houghton; Fiscal Year: 2001
    ..S. and worldwide. Current estimates for this market are 30-50 million dollars/year but could be greater if blood bank testing is mandated even on a regional basis. ..
  22. A Rickettsial Symbiont Model for the Control of Tick-borne Diseases
    Jianmin Zhong; Fiscal Year: 2009
    ..Results from the project would be used to design novel control measures that could significantly block the transmission of the Rickettsia species in I. pacificus and decrease the economic losses and disease transmission by ticks. ..
  23. BIOSYSTEMATICS OF MEDICALLY IMPORTANT TICK VECTORS
    JAMES KEIRANS; Fiscal Year: 2003
    ..Little information is available on Borrelia and Ehrlichia spp from Central and South America. We intend to check archived Ixodes species from this area using PCR methods. ..
  24. Prevention of Lyme Disease in Connecticut
    Matthew Cartter; Fiscal Year: 2007
    ..abstract_text> ..
  25. Antigenic variation of Anaplasma marginale
    PATRICK MEEUS; Fiscal Year: 2003
    ..The program provides an excellent framework for the proposed training. ..
  26. DEVELOPMENT OF PCR BASED ASSAY FOR BABESIOSIS
    BITA NAKHAI; Fiscal Year: 1999
    ..equii (agents of Lyme Disease, Babesiosis and Ehrlichiosis, respectively) will provide a cost effective, highly sensitive screen for all three tick-borne diseases in a single sample. ..
  27. Development of Paratransgenic ticks for Disease Control
    Ulrike Munderloh; Fiscal Year: 2001
    ..Finally, we will work towards 3. stable transformation of A. peacockii with cecropina will then test the transformants for antimicrobial activity in vitro and in ticks, and by sequence analysis. ..
  28. Immunity directed against MSP 2 during anaplasmosis
    Jeffrey Abbott; Fiscal Year: 2004
    ..marginale and other ehrlichial organisms that cause disease in animals and humans, especially the closely related agent of HGE, E. phagocytophila ..
  29. TICK-BORNE DISEASE PANEL TEST
    Andrew Levin; Fiscal Year: 2000
    ..The speed and simplicity of the test will establish a new industry standard and open the expanding market for tick- borne testing to the average, non-specialty clinical laboratory. ..
  30. Neurpeptidergic control of the salivary gland in the black-legged tick, Ixodes sc
    Yoonseong Park; Fiscal Year: 2010
    ..This research is eventually expected to lead to the design of compounds and vaccines to disrupt the salivary functions and to prevent disease transmissions by ticks, ultimately improving human health. ..
  31. Ehrlichia Glycoprotein Modulation of Macrophage Gene Expression
    Jere McBride; Fiscal Year: 2009
    ..HME is an emerging public health concern, and this research will facilitate development of new therapeutic interventions against one of the most prevalent life-threatening tick-borne diseases in North America. ..
  32. DETECTION AND RISK OF EHRLICHIAL DISEASES
    RICHARD FALCO; Fiscal Year: 2000
    ....
  33. A Zeiss LSM 510 Confocal Microscope for Medical Research
    Ruth Montgomery; Fiscal Year: 2004
    ..Thus this confocal microscope would be the basis of a core facility to assure that these investigators will have adequate access to state-of-the-art imaging techniques. ..
  34. Molcular detection of weaponized arenaviruses
    Remi Charrel; Fiscal Year: 2003
    ..The ultimate goal is to propose a ready-to-use diagnostic kit for the detection and characterization of weaponized arenaviruses. ..
  35. Topical Antibiotics to Prevent Lyme Disease
    Gary Wormser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  36. Perpetuation of Francisella tularensis
    Sam R Telford; Fiscal Year: 2010
    ..Taken together, these observations will provide a basis for understanding how the agent of tularemia is perpetuated on Martha's Vineyard, and why pneumonic human disease is prevalent there. ..
  37. Virulence and Immunity of Granulocytic Ehrlichiae
    JOHN DUMLER; Fiscal Year: 2007
    ..This information will provide a framework for rational design of therapies aimed at modulating immune injury and could foster design of preventative measures aimed at immunization. ..
  38. Ehrlichia chaffeensis protective proteins
    David H Walker; Fiscal Year: 2010
    ..chaffeensis. ..
  39. Gammacell-220 Excel Refurbished Research Irradiator
    David Walker; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  40. HEALTH BURDERN OF COINFECTING DEER ASSOCIATED ZOONOSES
    Peter Krause; Fiscal Year: 2001
    ..The density of deer will be estimated in each site. This proposed effort will help define the health burden imposed on people residing in proximity to deer and will contribute to diagnosis and case-management of apparent Lyme disease. ..
  41. Food Safety Task Force Conference
    Timothy Jones; Fiscal Year: 2005
    ..Abstract Not Provided ..
  42. Virulence and Immunity of Granulocytic Ehrlichiae
    JOHN DUMLER; Fiscal Year: 2005
    ..This information will provide the framework for rational design of new therapies aimed at modulating immune mechanisms and design of preventative measures aimed at immunization. ..
  43. Proximal determinants of risk for tularemia outbreaks
    Sam Telford; Fiscal Year: 2004
    ..tularensis in the environment; and, ultimately, a better understanding of F. tularensis-host interactions. ..