renal artery obstruction

Summary

Summary: Narrowing or occlusion of the renal arteries. It is due usually to atherosclerosis, fibromuscular dysplasia, thrombosis, embolism, or external pressure. It may result in renovascular hypertension.

Top Publications

  1. ncbi Distinct renal injury in early atherosclerosis and renovascular disease
    Alejandro R Chade
    Department of Internal Medicine, Division of Hypertension, Mayo Clinic, Rochester, Minn 55905, USA
    Circulation 106:1165-71. 2002
  2. pmc Mechanisms of tissue injury in renal artery stenosis: ischemia and beyond
    Lilach O Lerman
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Prog Cardiovasc Dis 52:196-203. 2009
  3. pmc Preserved oxygenation despite reduced blood flow in poststenotic kidneys in human atherosclerotic renal artery stenosis
    Monika L Gloviczki
    Department of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 55:961-6. 2010
  4. ncbi Guidelines for the reporting of renal artery revascularization in clinical trials. American Heart Association
    John H Rundback
    Circulation 106:1572-85. 2002
  5. ncbi Renal artery angioplasty and stent placement: predictors of a favorable outcome
    M W Burket
    Divisions of Cardiology and Nephrology, Department of Medicine, Medical College of Ohio, USA
    Am Heart J 139:64-71. 2000
  6. pmc Endothelial progenitor cells restore renal function in chronic experimental renovascular disease
    Alejandro R Chade
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 119:547-57. 2009
  7. pmc Embolic protection device use in renal artery stent placement
    Mallik R Thatipelli
    St Elizabeth s Medical Center, Boston, Massachusetts, USA
    J Vasc Interv Radiol 20:580-6. 2009
  8. pmc Endothelial progenitor cells homing and renal repair in experimental renovascular disease
    Alejandro R Chade
    Divisions of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Stem Cells 28:1039-47. 2010
  9. ncbi Antioxidant intervention blunts renal injury in experimental renovascular disease
    Alejandro R Chade
    Department of Internal Medicine, Division of Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Am Soc Nephrol 15:958-66. 2004
  10. ncbi The benefit of renal artery stenting in patients with atheromatous renovascular disease and advanced chronic kidney disease
    Philip A Kalra
    Department of Renal Medicine, Salford Royal Hospital, Salford, United Kingdom
    Catheter Cardiovasc Interv 75:1-10. 2010

Detail Information

Publications268 found, 100 shown here

  1. ncbi Distinct renal injury in early atherosclerosis and renovascular disease
    Alejandro R Chade
    Department of Internal Medicine, Division of Hypertension, Mayo Clinic, Rochester, Minn 55905, USA
    Circulation 106:1165-71. 2002
    ..This study was designed to test the hypothesis that concurrent early atherosclerosis and hypoperfusion might have greater early deleterious effects on the function and structure of the stenotic kidney...
  2. pmc Mechanisms of tissue injury in renal artery stenosis: ischemia and beyond
    Lilach O Lerman
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Prog Cardiovasc Dis 52:196-203. 2009
    ..Identification of specific pathways producing progressive renal injury may enable development of targeted interventions to block these pathways and preserve the stenotic kidney...
  3. pmc Preserved oxygenation despite reduced blood flow in poststenotic kidneys in human atherosclerotic renal artery stenosis
    Monika L Gloviczki
    Department of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 55:961-6. 2010
    ..1+/-2.2 versus 58.1+/-1.2; P=0.006). These data indicate that, although stenosis reduced blood flow and volume, cortical and medullary oxygenation was preserved under these conditions...
  4. ncbi Guidelines for the reporting of renal artery revascularization in clinical trials. American Heart Association
    John H Rundback
    Circulation 106:1572-85. 2002
  5. ncbi Renal artery angioplasty and stent placement: predictors of a favorable outcome
    M W Burket
    Divisions of Cardiology and Nephrology, Department of Medicine, Medical College of Ohio, USA
    Am Heart J 139:64-71. 2000
    ..The current study was designed to determine which factors are predictive of improved blood pressure and renal function when patients with renal artery stenosis are treated with renal artery angioplasty and stent placement...
  6. pmc Endothelial progenitor cells restore renal function in chronic experimental renovascular disease
    Alejandro R Chade
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 119:547-57. 2009
    ..We investigated whether replenishment with EPCs would protect the renal microcirculation in chronic experimental renovascular disease...
  7. pmc Embolic protection device use in renal artery stent placement
    Mallik R Thatipelli
    St Elizabeth s Medical Center, Boston, Massachusetts, USA
    J Vasc Interv Radiol 20:580-6. 2009
    ....
  8. pmc Endothelial progenitor cells homing and renal repair in experimental renovascular disease
    Alejandro R Chade
    Divisions of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Stem Cells 28:1039-47. 2010
    ..Importantly, manipulation of homing signals may potentially allow therapeutic opportunities to increase endogenous EPC recruitment...
  9. ncbi Antioxidant intervention blunts renal injury in experimental renovascular disease
    Alejandro R Chade
    Department of Internal Medicine, Division of Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Am Soc Nephrol 15:958-66. 2004
    ..This study supports critical pathogenic contribution of increased oxidative stress to renal injury and scarring in RVD and suggests a role for antioxidant strategies in preserving the atherosclerotic and ischemic kidney...
  10. ncbi The benefit of renal artery stenting in patients with atheromatous renovascular disease and advanced chronic kidney disease
    Philip A Kalra
    Department of Renal Medicine, Salford Royal Hospital, Salford, United Kingdom
    Catheter Cardiovasc Interv 75:1-10. 2010
    ..We aimed to investigate whether differences in outcomes after revascularization compared to medical management might be observed in ARVD patients if stratified by their CKD classes...
  11. ncbi Blood oxygen level-dependent measurement of acute intra-renal ischemia
    Laurent Juillard
    Department of Physiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 65:944-50. 2004
    ..This study was therefore designed to test if BOLD can detect the characteristic of renal hypoxia induced by RAS...
  12. pmc Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis
    Alfonso Eirin
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Stem Cells 30:1030-41. 2012
    ..This study suggests a unique and novel therapeutic potential for MSC in restoring renal function when combined with PTRA in chronic experimental renovascular disease...
  13. ncbi Epidemiology, associated factors, and prognostic outcomes of renal artery stenosis in chronic heart failure assessed by magnetic resonance angiography
    Ramesh de Silva
    Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, East Yorkshire, United Kingdom
    Am J Cardiol 100:273-9. 2007
    ..Interventional trials on renal revascularization are underway that contain subsets of patients with HF that may provide evidence on how best to manage RAS in this setting...
  14. ncbi Renal artery revascularization improves heart failure control in patients with atherosclerotic renal artery stenosis
    Garvan C Kane
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 25:813-20. 2010
    ..However, the long-term effects of renal artery revascularization on cardiovascular outcomes in HF patients are not well studied...
  15. pmc Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure
    Frederic Favreau
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 78:1110-8. 2010
    ..Thus, our study shows that revascularization of a stenotic renal artery restores the glomerular filtration rate and renal endothelial function 4 weeks later. Renal hemodynamics and structure, however, are incompletely resolved...
  16. ncbi Prevalence of renovascular disease in the elderly: a population-based study
    Kimberley J Hansen
    Division of Surgical Sciences, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1095, USA
    J Vasc Surg 36:443-51. 2002
    ....
  17. ncbi ACC/AHA Guidelines for the Management of Patients with Peripheral Arterial Disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Associations for Vascular Surgery/Society for Vascular Surgery, Society
    Alan T Hirsch
    J Vasc Interv Radiol 17:1383-97; quiz 1398. 2006
  18. pmc Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension
    Gina M Warner
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Physiol Renal Physiol 302:F1455-64. 2012
    ..We conclude that abrogation of TGF-β/Smad3 signaling confers protection against the development of fibrosis and atrophy in RAS...
  19. pmc Mesenchymal stem cells and endothelial progenitor cells decrease renal injury in experimental swine renal artery stenosis through different mechanisms
    Xiang Yang Zhu
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Stem Cells 31:117-25. 2013
    ..These results support development of cell-based approaches for management of renovascular disease and suggest cell selection based on the underlying pathophysiology of kidney injury...
  20. pmc Persistent kidney dysfunction in swine renal artery stenosis correlates with outer cortical microvascular remodeling
    Alfonso Eirin
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Renal Physiol 300:F1394-401. 2011
    ..MV loss and fibrosis in swine ARAS might account for persistent renal dysfunction after PTRS and underscore the need to assess renal parenchymal disease before revascularization...
  21. ncbi Atherosclerotic renovascular disease and the heart
    Constantina Chrysochou
    Renal Department, Salford Royal Hospital, Salford, Greater Manchester, M6 8HD, UK
    J Ren Care 36:146-53. 2010
    ..The close link between cardiac and renal pathophysiology in ARVD raises the possibility that renal revascularisation might confer a benefit to cardiac morphology and function. This is the subject of ongoing randomised controlled trials...
  22. ncbi Cardiovascular morbidity and mortality and renal artery stenosis
    William R Colyer
    Cardiovascular Division, University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, USA
    Prog Cardiovasc Dis 52:238-42. 2009
    ..Ongoing clinical trials such as the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) trial will ultimately help to determine the best strategies to limit the morbidity and mortality associated with RAS...
  23. ncbi Dispelling the myth: the use of renin-angiotensin blockade in atheromatous renovascular disease
    Constantina Chrysochou
    Renal Department, Salford Royal Hospital, Manchester Academic Health Science Centre, The University of Manchester, Salford, UK
    Nephrol Dial Transplant 27:1403-9. 2012
    ..This reservation is mostly because of fear of precipitating acute renal deterioration. We aimed to study whether RAB can be used safely in ARVD patients and whether it altered their outcome...
  24. ncbi Severity of renal vascular disease predicts mortality in patients undergoing coronary angiography
    P J Conlon
    Department of Nephrology, Beaumont Hospital, Dublin, Ireland
    Kidney Int 60:1490-7. 2001
    ..Our current study expands on this cohort, investigating the effect of the severity of RAS on all-cause mortality...
  25. pmc Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney
    Victor H Urbieta-Caceres
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Renal Physiol 299:F135-40. 2010
    ..These observations underscore the direct intrarenal effect of atherogenic factors on the kidneys...
  26. pmc Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis
    Behzad Ebrahimi
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Physiol Renal Physiol 302:F1478-85. 2012
    ..These results support further development of cell-based therapy as an adjunct to revascularization of RAS...
  27. ncbi Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia
    Alejandro R Chade
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First St S W, Rochester, Minnesota 55905, USA
    FASEB J 20:1706-8. 2006
    ..These novel renoprotective effects suggest a role for simvastatin in preserving the ischemic kidney in chronic RAS...
  28. ncbi Controversial treatment of atherosclerotic renal vascular disease: the cardiovascular outcomes in renal atherosclerotic lesions trial
    Lance D Dworkin
    Brown Medical School, Providence, Rhode Island, USA
    Hypertension 48:350-6. 2006
  29. ncbi Worsening renal failure in older chronic kidney disease patients with renal artery stenosis concurrently on renin angiotensin aldosterone system blockade: a prospective 50-month Mayo-Health-System clinic analysis
    M A C Onuigbo
    College of Medicine, Mayo Clinic, Rochester, MN, USA
    QJM 101:519-27. 2008
    ..Current literature regarding worsening renal failure in CKD patients with RAS is based almost wholly on retrospective studies, and therefore may be poorly understood...
  30. ncbi Cortical microvascular remodeling in the stenotic kidney: role of increased oxidative stress
    Xiang Yang Zhu
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Arterioscler Thromb Vasc Biol 24:1854-9. 2004
    ..Mechanisms of renal injury distal to renal artery stenosis (RAS) remain unclear. We tested the hypothesis that it involves microvascular remodeling consequent to increased oxidative stress...
  31. ncbi Indications for renal arteriography at the time of coronary arteriography: a science advisory from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology, and the Councils on Cardi
    Christopher J White
    Circulation 114:1892-5. 2006
    ..This multispecialty consensus document describes the rationale for patient selection for screening renal angiography at the time of cardiac catheterization...
  32. ncbi Renal artery stenosis: a common, treatable cause of renal failure?
    S C Textor
    Divisions of Hypertension and Nephrology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Annu Rev Med 52:421-42. 2001
    ..The decision to recommend revascularization remains a difficult balance between the risks and expense of the procedure and the undoubted benefits that accrue if renal function is successfully stabilized...
  33. pmc Reversal of renal dysfunction by targeted administration of VEGF into the stenotic kidney: a novel potential therapeutic approach
    Alejandro R Chade
    Dept of Physiology and Biophysics, Dept of Medicine, Univ of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216 4505, USA
    Am J Physiol Renal Physiol 302:F1342-50. 2012
    ....
  34. ncbi Renal artery stenosis in patients with coronary artery disease
    Tadeusz Przewłocki
    Krakowski Szpital Specjalistyczny im Jana Pawła II, ul Pradnicka 80, 31 202 Krakow, Poland
    Kardiol Pol 66:856-62; discussion 863-4. 2008
    ..In RAS patients a significant increase in prevalence of coronary artery disease (CAD) as well as revascularisation rate and mortality rate was observed...
  35. ncbi Radionuclide renography: a personal approach
    A Taylor
    Emory University School of Medicine, Atlanta, GA, USA
    Semin Nucl Med 29:102-27. 1999
    ..To avoid unrealistic expectations on the part of the referring physician, it is often helpful to explain the likely differences in test results in these two-patient populations prior to the study...
  36. ncbi Renovascular hypertension: a unique cause of unilateral focal segmental glomerulosclerosis
    Bassam Alchi
    Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Hypertens Res 29:203-7. 2006
    ..This case illustrates the heterogeneous effect of the renin-angiotensin system on either kidney in patients with renovascular hypertension due to unilateral renal artery stenosis...
  37. ncbi Controversies in renal artery stenosis: a review by the American Society of Nephrology Advisory Group on Hypertension
    Adeera Levin
    Denver Health Medical Center, Denver, Colo 80204, USA
    Am J Nephrol 27:212-20. 2007
    ..The practice may be hazardous and should be critically examined. A dialog and closer cooperation between cardiologists and nephrologists is warranted and organized programs should be formulated to address this problem...
  38. pmc RADAR - A randomised, multi-centre, prospective study comparing best medical treatment versus best medical treatment plus renal artery stenting in patients with haemodynamically relevant atherosclerotic renal artery stenosis
    Uwe Schwarzwälder
    Department Angiology, Herz Zentrum Bad Krozingen, Südring 15, 79189 Bad Krozingen, Germany
    Trials 10:60. 2009
    ....
  39. ncbi Incidental renal artery stenosis is an independent predictor of mortality in patients with peripheral vascular disease
    Kwok Wai Mui
    Division of Nephrology and Deptartment of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Am Soc Nephrol 17:2069-74. 2006
    ..Whether RAS is a marker for or, alternatively, a mediator of the poor prognosis and whether prognosis can be improved by specific intervention should be the subject of future prospective studies...
  40. ncbi Epidemiology and natural history of atherosclerotic renovascular disease
    Constantina Chrysochou
    Renal Department, Salford Royal Hospital, Greater Manchester, United Kingdom
    Prog Cardiovasc Dis 52:184-95. 2009
    ..Understanding of the natural history of renal artery stenosis may enable intensified treatment strategies to reduce associated risk and improve patient prognosis...
  41. ncbi Renal artery stent revascularization with embolic protection in patients with ischemic nephropathy
    A Holden
    Department of Radiology, Auckland City Hospital, Park Road, Grafton, Auckland, New Zealand
    Kidney Int 70:948-55. 2006
    ..Patients most likely to receive the greatest benefit are those with mild baseline chronic renal insufficiency and a recent decline in renal function...
  42. ncbi Atherosclerotic renal artery stenosis: overtreated but underrated?
    Stephen C Textor
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    J Am Soc Nephrol 19:656-9. 2008
    ..Most important, nephrologists await development of tools to predict reliably when renal parenchymal injury is beyond recovery and/or when revascularization can produce meaningful salvage of kidney function...
  43. ncbi Analysis of renal function after aneurysm repair with a device using suprarenal fixation (Zenith AAA Endovascular Graft) in contrast to open surgical repair
    Roy K Greenberg
    Division of Vascular Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Vasc Surg 39:1219-28. 2004
    ..This study was undertaken to assess the effect on renal function of open surgery and endovascular abdominal aortic aneurysm (AAA) repair with suprarenal fixation with the Zenith device...
  44. ncbi Clinical outcomes after percutaneous revascularization versus medical management in patients with significant renal artery stenosis: a meta-analysis of randomized controlled trials
    Dharam J Kumbhani
    Department of Cardiovascular Medicine, Cleveland Clinic, OH 44195, USA
    Am Heart J 161:622-630.e1. 2011
    ..We sought to systematically evaluate whether percutaneous revascularization is associated with additional clinical benefit in patients with renal artery stenosis (RAS) as compared with medical management alone...
  45. ncbi Proteinuria in renal artery occlusion is related to active renin concentration and contralateral kidney size
    Patrick Rossignol
    Hypertension Unit, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75908 Paris Cedex 15, France
    J Hypertens 20:139-44. 2002
    ..We analysed patient characteristics at presentation to identify the factors associated with proteinuria...
  46. ncbi Transplant renal artery stenosis associated with acute cytomegalovirus infection: resolution following ganciclovir administration
    Mohammad R Ardalan
    Department of Nephrology, Tabriz University of Medical Sciences, Tabriz, Iran
    Ren Fail 31:982-4. 2009
    ....
  47. ncbi Risk factors and long-term outcome of transplant renal artery stenosis in adult recipients after treatment by percutaneous transluminal angioplasty
    V Audard
    Department of Nephrology and Transplantation and Université Paris XII, Henri Mondor Hospital, Creteil, France
    Am J Transplant 6:95-9. 2006
    ..03). Our study suggests that CMV infection and DGF are two reliable risk factors for TRAS. Despite treatment by PTA with primary successful results, TRAS significantly affects long-term graft outcome...
  48. ncbi Renal arterial stenosis in renal allografts: retrospective study of predisposing factors and outcome after percutaneous transluminal angioplasty
    N H Patel
    Department of Radiology, Indiana University Medical Center, 550 N University Blvd, Rm 0279, Indianapolis, IN 46202, USA
    Radiology 219:663-7. 2001
    ..To determine the predisposing factors to transplant renal arterial stenosis (TRAS) and assess the outcome of percutaneous transluminal angioplasty (PTA) as the primary treatment...
  49. ncbi Exacerbation of chronic renovascular hypertension and acute renal failure in heme oxygenase-1-deficient mice
    P Wiesel
    Program of Developmental Cardiovascular Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Circ Res 88:1088-94. 2001
    ..Moreover, renal artery clipping leads to an acute increase in ischemic damage and death in the absence of HO-1...
  50. ncbi Imaging modalities for renal artery stenosis in suspected renovascular hypertension: prospective intraindividual comparison of color Doppler US, CT angiography, GD-enhanced MR angiography, and digital substraction angiography
    C Rountas
    Department of Radiology, University of Thessalia, Larissa, Greece
    Ren Fail 29:295-302. 2007
    ..The concept of an imaging algorithm including US as screening test when appropriate and CTA or MRA as the second step-procedure is suggested. Therefore, DSA may be reserved for cases with major discrepancies or therapeutic interventions...
  51. ncbi The prevalence of atherosclerotic renal artery stenosis in risk groups: a systematic literature review
    Quirijn de Mast
    Department of General Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Hypertens 27:1333-40. 2009
    ..We performed a literature review and analysis to improve the insight in the prevalence of renal artery stenosis (RAS) in risk groups...
  52. ncbi Noninvasive evaluation of a novel swine model of renal artery stenosis
    L O Lerman
    Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Soc Nephrol 10:1455-65. 1999
    ..Electron-beam computerized tomography shows promise to noninvasively quantify, follow-up, and study changes in concurrent, in vivo intrarenal hemodynamics and segmental tubular function in renovascular hypertension...
  53. ncbi Frequency of coronary artery disease in patients with renal artery stenosis without clinical manifestations of coronary insufficiency
    Fábio Cardoso de Carvalho
    Section of Cardiology, Department of Internal Medicine, Botucatu Medical School, Universidade Estadual Paulista, Sao Paulo, Brazil
    Am J Hypertens 19:1125-8. 2006
    ..The data suggest that in patients with RAS the frequency of silent CAD is high and cannot be predicted on clinical grounds alone, therefore coronary angiography should be routinely recommended in the same setting...
  54. ncbi Evaluation of the safety and effectiveness of renal artery stenting after unsuccessful balloon angioplasty: the ASPIRE-2 study
    Krishna Rocha-Singh
    Vascular Medicine Program, Prairie Heart Institute, Springfield, Illinois 62794 9420, USA
    J Am Coll Cardiol 46:776-83. 2005
    ..This study sought to define the safety and durability of renal stenting after suboptimal/failed renal artery angioplasty in patients with suspected renovascular hypertension...
  55. ncbi Atherosclerotic renovascular disease in United States patients aged 67 years or older: risk factors, revascularization, and prognosis
    Philip A Kalra
    Department of Renal Medicine, Hope Hospital, Salford, United Kingdom
    Kidney Int 68:293-301. 2005
    ..Although atherosclerotic renovascular disease is increasingly recognized in chronic kidney disease, few national level studies have examined its clinical epidemiology...
  56. ncbi Transplant renal artery stenosis
    Simona Bruno
    Department of Medicine and Transplantation, Azienda Ospedaliera, Ospedali Riuniti di Bergamo Mario Negri Institute for Pharmacological Research, Bergamo, Italy
    J Am Soc Nephrol 15:134-41. 2004
    ..Surgery is indicated for stenoses that cannot be treated by PTA or that recur after it. Doppler ultrasonography is the procedure of choice to evaluate graft perfusion before and after revascularization...
  57. ncbi Treatment of reoccurring instent restenosis following reintervention after stent-supported renal artery angioplasty
    Thomas Zeller
    Department Angiology, Herz Zentrum Bad Krozingen, Bad Krozingen, Germany
    Catheter Cardiovasc Interv 70:296-300. 2007
    ....
  58. ncbi Suprarenal fixation of endovascular aortic stent grafts: assessment of medium-term to long-term renal function by analysis of juxtarenal stent morphology
    Mark E O'donnell
    Department of Vascular Surgery, Royal Victoria Hospital, Belfast, United Kingdom
    J Vasc Surg 45:694-700. 2007
    ..A unique validated three-dimensional intraluminal imaging technique was used to analyze the effect of suprarenal stent position relative to renal artery orifices. Also analyzed was its medium-term to long-term effects on renal function...
  59. ncbi Prevalence of renal artery stenosis in autopsy patients with stroke
    S Kuroda
    Division of Nephrology, National Cardiovascular Center, Osaka, Japan
    Stroke 31:61-5. 2000
    ..Thus, information on renal artery involvement in atherosclerotic diseases could be important. We investigated the prevalence of renal artery stenosis in autopsied patients with stroke over 40 years of age...
  60. pmc Ischaemic nephropathy secondary to atherosclerotic renal artery stenosis: clinical and histopathological correlates
    Mira T Keddis
    Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Nephrol Dial Transplant 25:3615-22. 2010
    ..We correlated the histopathological findings and clinical characteristics in selected patients with atherosclerotic RAS who underwent nephrectomy of their small kidneys for resistant renovascular hypertension...
  61. ncbi Delay of dialysis in end-stage renal failure: prospective study on percutaneous renal artery interventions
    S Korsakas
    Swiss Cardiovascular Center, Division of Angiology, University Hospital, Bern, Switzerland
    Kidney Int 65:251-8. 2004
    ..We studied the effect of percutaneous renal artery intervention (PRI) in patients with advanced, progressive disease at risk for renal failure, hypothesizing a beneficial effect...
  62. ncbi Embolic protection and platelet inhibition during renal artery stenting
    Christopher J Cooper
    Cardiovascular Division, University of Toledo, 3000 Arlington Ave, MS 1036, Toledo, OH 43614, USA
    Circulation 117:2752-60. 2008
    ..Although atheroembolization can cause renal dysfunction during renal stent procedures, whether adjunctive use of embolic protection devices or glycoprotein IIb/IIIa inhibitors improves renal function is unknown...
  63. ncbi A mitochondrial permeability transition pore inhibitor improves renal outcomes after revascularization in experimental atherosclerotic renal artery stenosis
    Alfonso Eirin
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Hypertension 60:1242-9. 2012
    ..Potent antiapoptotic and antioxidant effects provide Bendavia a novel therapeutic potential for improving kidney outcomes after PTRA in experimental ARAS...
  64. ncbi Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial
    Liesbeth Bax
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Ann Intern Med 150:840-8, W150-1. 2009
    ..Little is known about the efficacy and safety of renal artery stenting in patients with atherosclerotic renal artery stenosis (ARAS) and impaired renal function...
  65. ncbi Enhanced flow velocity after stenting of renal arteries is associated with decreased renal function
    Matthias Girndt
    Medical Department IV, University of the Saarland, Homburg Saar, Germany
    Nephron Clin Pract 105:c84-9. 2007
    ..Duplex sonography is an established noninvasive technique for patient follow-up. There is lack of evidence that routine monitoring of asymptomatic patients with stable blood pressure is needed...
  66. ncbi Primary stenting for atherosclerotic renal artery stenosis
    Olivier Steichen
    Assistance Publique Hopitaux de Paris, Centre d Investigations Cliniques, Hopital Europeen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Paris, France
    J Vasc Surg 51:1574-1580.e1. 2010
    ..However, only recently have large randomized trials rigorously evaluated its clinical benefit...
  67. ncbi Cardiovascular risk factors in hypertensive patients with coronary artery disease and coexisting renal artery stenosis
    Zofia Dzielinska
    1st Department of Coronary Artery Disease, Institute of Cardiology, Warsaw, Poland
    J Hypertens 25:663-70. 2007
    ..The aim of our study was to examine the association between the presence of atherosclerotic renal artery stenosis (RAS) and coexisting cardiovascular risk factors in hypertensive patients with coronary artery disease (CAD)...
  68. ncbi Renal artery stenting for renal insufficiency in solitary kidney in 26 patients
    A Chatziioannou
    Department of Radiology, Areteion Hospital, Athens, Greece
    Eur J Vasc Endovasc Surg 23:49-54. 2002
    ..to present our experience with stent placement in renal arteries in solitary kidneys for treating renal insufficiency...
  69. ncbi Revised duplex criteria and outcomes for renal stents and stent grafts following endovascular repair of juxtarenal and thoracoabdominal aneurysms
    Walid Mohabbat
    Department of Vascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Vasc Surg 49:827-37; discussion 837. 2009
    ..To assess outcomes and develop duplex scan criteria that will reliably determine the luminal status of covered and uncovered renal stents following fenestrated and branched endovascular repair...
  70. ncbi Outcome after endovascular revascularization of atherosclerotic renal artery stenosis
    H Eklöf
    Department of Radiology, Uppsala University Hospital, Uppsala, Sweden
    Acta Radiol 50:256-64. 2009
    ..The goal of this treatment is to achieve a dialysis-free life or a well-controlled blood pressure with reduced risks of cardiovascular complications...
  71. ncbi Renal artery stenosis is not associated with the development of acute renal failure following coronary artery bypass grafting
    Peter J Conlon
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Ren Fail 27:81-6. 2005
    ..We hypothesized that renal artery stenosis (RAS), causing occult renal ischemia, may be an important factor contributing to development of ARF after CABG surgery...
  72. ncbi Detection of renal artery stenosis: prospective comparison of captopril-enhanced Doppler sonography, captopril-enhanced scintigraphy, and MR angiography
    S D Qanadli
    Department of Radiology, CHUM, , 1560 Sherbrooke St. E, , Quebec H2L 4M1, Canada
    AJR Am J Roentgenol 177:1123-9. 2001
    ..The use of captopril-enhanced Doppler sonography in combination with gadolinium-enhanced MR angiography for identifying renal artery stenosis needs to be evaluated with a cost-effectiveness analysis...
  73. ncbi Progression of renal artery stenosis in patients undergoing cardiac catheterization
    J J Crowley
    Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 136:913-8. 1998
    ..This study assesses the prevalence, risk factors for progression, and effect on renal function of angiographically demonstrated renal artery disease in patients undergoing cardiac catheterization...
  74. ncbi Chronic renal ischemia: implications for cardiovascular disease risk
    Timothy P Murphy
    Department of Diagnostic Imaging, Rhode Island Hospital, Brown University Medical School, 593 Eddy Street, Providence, Rhode Island 02903, USA
    J Vasc Interv Radiol 13:1187-98. 2002
    ..Clinical trials should examine a full range of CV and renal outcomes, not just blood pressure, to adequately assess the merits of revascularization...
  75. ncbi Renal artery stenosis: comparative assessment by unenhanced renal artery MRA versus contrast-enhanced MRA
    Michael M Y Khoo
    Department of MRI, St Mary s Hospital, Imperial College NHS Trust, London, UK
    Eur Radiol 21:1470-6. 2011
    ..To evaluate steady-state free precession (SSFP) non-contrast-enhanced MR angiography (Unenhanced-MRA) versus conventional contrast-enhanced MR angiography (CE-MRA) in the detection of renal artery stenosis (RAS)...
  76. ncbi Epidemiology of renal dysfunction and patient outcome in atherosclerotic renal artery occlusion
    Ching M Cheung
    Department of Renal Medicine, Hope Hospital, Salford, England
    J Am Soc Nephrol 13:149-57. 2002
    ..This study reinforces the importance of intrarenal vascular and parenchymal disease in the etiology of renal dysfunction in ARVD...
  77. ncbi Is it necessary to stent renal artery stenosis patients before cardiopulmonary bypass procedures?
    Bin Zheng
    Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
    Chin Med J (Engl) 124:1453-7. 2011
    ..The aim of this retrospective study was to investigate whether stent implantation before cardiopulmonary bypass has beneficial effect on development of AKI in renal artery stenosis (RAS) patients...
  78. ncbi Evaluation of renal artery stenosis in dialysis patients
    Jamie P Dwyer
    Division of Nephrology Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Semin Dial 22:519-23. 2009
    ..The risks of intervention must be weighed against the potential for renal recovery, even when predictors of success are not known with certainty...
  79. ncbi Preliminary study of the use of drug-eluting stents in atherosclerotic renal artery stenoses 4 mm in diameter or smaller
    Sanjay Misra
    Department of Radiology, Mayo Clinic College of Medicine, 200 First Street Southwest, Alfred 6460, Rochester, MN 55905, USA
    J Vasc Interv Radiol 19:833-9. 2008
    ..To describe restenosis and clinical outcomes with drug-eluting stents (DESs) and compare them to those of bare metal stents (BMSs) in the treatment of symptomatic atherosclerotic renal artery stenosis (RAS) in the same patients...
  80. pmc Arteriosclerotic renal artery stenosis: conservative versus interventional management
    Christlieb Haller
    Medizinische Klinik, Hegau Klinikum, Virchowstr 10, 78221 Singen, Germany
    Heart 88:193-7. 2002
  81. ncbi Delicate percutaneous renal artery stenting minimizes postoperative renal injury and protects kidney in patients with severe atherosclerotic renal artery stenosis and impaired renal function
    Chen Rong Tsao
    Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan
    Int Heart J 46:1061-72. 2005
    ..In conclusion, delicately practiced PTRAS can reduce the rate of postprocedural renal deterioration in patients with impaired renal function, and should be adopted in every renal intervention...
  82. ncbi Renal artery stenosis evaluation: diagnostic performance of gadobenate dimeglumine-enhanced MR angiography--comparison with DSA
    Gilles Soulez
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, University of Montreal, 1560 Sherbrooke East, Montreal, QC, Canada H2V 2Z2
    Radiology 247:273-85. 2008
    ..1 mmol per kilogram of body weight gadobenate dimeglumine for depiction of significant steno-occlusive disease (> or =51% stenosis) of renal arteries, with digital subtraction angiography (DSA) as reference standard...
  83. ncbi Treatment of atherosclerotic ostial renal artery stenosis with the intravascular stent
    K R Tuttle
    The Heart Institute of Spokane and Sacred Heart Medical Center, WA 99204, USA
    Am J Kidney Dis 32:611-22. 1998
    ..Control of hypertension improves in most patients. Renal function stabilizes or improves in the majority of patients, even those with severe renal failure. These favorable outcomes are maintained long term...
  84. ncbi Renal artery stent placement for restoration of renal function in hemodialysis recipients with renal artery stenosis
    Mallik Thatipelli
    Division of Cardiology, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street Southwest, Alfred 6460, Rochester, MN 55902, USA
    J Vasc Interv Radiol 19:1563-8. 2008
    ..We present our outcomes of discontinuation of hemodialysis after treating patients with RAS by stent placement on acute (< or =30 days of hemodialysis) and chronic hemodialysis (>30 days)...
  85. ncbi [High incidence of renal artery stenosis in patients undergoing coronary angiography]
    Jingang Yang
    Cardiovascular Center, Tongren Hospital, Beijing 100730, China
    Zhonghua Nei Ke Za Zhi 41:24-7. 2002
    ..This study is to evaluate the prevalence of angiographically-determined renal artery stenosis in a patient population undergoing routine coronary angiography, and to identify the risk factors for renal artery stenosis...
  86. ncbi Factors influencing the need for target vessel revascularization after renal artery stenting
    Mark C Bates
    Vascular Center of Excellence, Charleston Area Medical Center, West Virginia School of Medicine Charleston Division, West Virginia, USA
    J Endovasc Ther 13:569-77. 2006
    ..To provide additional insight into factors that may be associated with the need for target vessel revascularization (TVR) following de novo renal artery stenting during long-term follow-up...
  87. ncbi Increasing the diagnostic yield of renal angiography for the diagnosis of atheromatous renovascular disease
    A E Shurrab
    Department of Renal Medicine, Hope Hospital, Stott Lane, Salford M6 8ES, UK
    Br J Radiol 74:213-8. 2001
    ..2%, specificity 97%). We plan to rationalize the criteria for angiography in the light of these findings, anticipating an increase in the diagnostic yield of renal angiography from its current 33.3% to above 42%...
  88. ncbi 64-Detector CT angiography in renal artery stent evaluation: prospective comparison with selective catheter angiography
    Clemens Steinwender
    Cardiovascular Division, Linz City Hospital, Krankenhausstrasse 9, A 4020 Linz, Austria
    Radiology 252:299-305. 2009
    ..To prospectively assess the diagnostic accuracy of 64-detector computed tomographic (CT) renal artery (RA) angiography for the evaluation of RA in-stent restenosis (ISR) by using selective catheter RA angiography as the reference standard...
  89. ncbi Assessment of renal artery stenosis using both resting pressures ratio and fractional flow reserve: relationship to angiography and ultrasonography
    Jacek Kadziela
    Institute of Cardiology, Warsaw, Poland
    Blood Press 20:211-7. 2011
    ..The best accuracy cut-off points for severe RAS predicting were 0.93 and 0.80, respectively...
  90. pmc Renovascular hypertension: screening and modern management
    Iris Baumgartner
    Department of Clinical and Interventional Angiology, Swiss Cardiovascular Center, University of Bern, Switzerland
    Eur Heart J 32:1590-8. 2011
    ....
  91. pmc Regional decreases in renal oxygenation during graded acute renal arterial stenosis: a case for renal ischemia
    Lizette Warner
    Department of Physiology and Biomedical Engineering, Mayo Clinic, ST 7, 200 First St SW, Rochester, MN 55905, USA
    Am J Physiol Regul Integr Comp Physiol 296:R67-71. 2009
    ..Furthermore, the notion that arteriovenous shunting and increased stoichiometric energy requirements are potential contributors toward ensuing hypoxia with graded and progressive acute RAS cannot be excluded...
  92. ncbi CT angiography of renal artery anatomy for evaluating embolic protection devices
    Mallik R Thatipelli
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    J Vasc Interv Radiol 18:842-6. 2007
    ..To determine which commercially available embolic protection devices are suitable for use in renal arteries...
  93. ncbi The effect of revascularization of renal artery stenosis on renal perfusion in patients with atherosclerotic renovascular disease
    Niina Koivuviita
    Department of Medicine, Turku University Hospital, Turku, Finland
    Nephrol Dial Transplant 27:3843-8. 2012
    ..It has been suggested that this may be due to effects of renal microvascular disease. Our aim was to measure the effect of renal artery stenosis (RAS) revascularization on renal perfusion in patients with renovascular disease...
  94. ncbi Embolic protection devices in patients with renal artery stenosis with chronic renal insufficiency: a clinical study
    Sanjay Misra
    Department of Radiology, Mayo Clinic College of Medicine, 200 First Street Southwest, Alfred 6460, Rochester, MN 55902, USA
    J Vasc Interv Radiol 19:1639-45. 2008
    ..To present clinical outcomes with the use of embolic protection devices (EPDs) and renal artery stents in patients with chronic renal insufficiency (CRI) and renal artery stenosis (RAS)...
  95. ncbi Renal artery assessment with nonenhanced steady-state free precession versus contrast-enhanced MR angiography
    Rolf Wyttenbach
    Department of Radiology, Ospedale San Giovanni Bellinzona, CH 6500 Bellinzona, Switzerland, and Department of Radiology, University of Aachen, Aachen, Germany
    Radiology 245:186-95. 2007
    ....
  96. ncbi Renovascular disease: effect of ACE gene deletion polymorphism and endovascular revascularization
    Francesca Pizzolo
    Section of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Policlinico Borgo Roma, 37134 Verona, Italy
    J Vasc Surg 39:140-7. 2004
    ....
  97. ncbi Renal artery stenting in patients with a solitary functioning kidney
    R Cioni
    Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    Cardiovasc Intervent Radiol 24:372-7. 2001
    ..To retrospectively evaluate the results of renal artery stenting in patients with renovascular disease and a solitary functioning kidney...
  98. ncbi Non-invasive investigations of potential renal artery stenosis in renal insufficiency
    Per Eriksson
    Nephrology IMH, Linkoping University, Sweden
    Nephrol Dial Transplant 25:3607-14. 2010
    ..The diagnostic value of non-invasive methods for diagnosing renal artery stenosis in patients with renal insufficiency is incompletely known...
  99. ncbi Efficacy of revascularization for renal artery stenosis caused by fibromuscular dysplasia: a systematic review and meta-analysis
    Ludovic Trinquart
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75908 Paris Cedex 15, France
    Hypertension 56:525-32. 2010
    ..The blood pressure outcome was strongly influenced by patient age...
  100. ncbi Treatment of renal artery in-stent restenosis with sirolimus-eluting stents
    Thomas J Kiernan
    Department of Interventional Cardiology and Vascular Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Vasc Med 15:3-7. 2010
    ..05). In conclusion, placement of a SES for the treatment of ISR in renal arteries is associated with high initial technical success but significant restenosis on duplex ultrasonography at follow-up...
  101. ncbi Peripheral vascular disease and renal transplant artery stenosis: a reappraisal of transplant renovascular disease
    B N Becker
    Department of Medicine, University of Wisconsin Medical School, Madison 53792, USA
    Clin Transplant 13:349-55. 1999
    ..Older transplant recipients, prone to peripheral vascular disease (PVD), may have pseudoRTAS with PVD involving their iliac system...

Research Grants15

  1. CT imaging for the assessment of kidney injury distal to renal artery stenosis
    Lilach O Lerman; Fiscal Year: 2013
    ..MV remodeling interferes with adaptation to ischemic insult (acute or chronic renal artery obstruction);3. MCP-1 contributes to MetS-induced renal microvascular alterations...
  2. MECHANISMS OF RENAL IMPAIRMENT IN HYPERCHOLESTEROLEMIA
    Lilach Lerman; Fiscal Year: 2003
    ..Aim # 4 is to characterize intrarenal morphology in the HC pig model using 3-d x-ray micro-CT of microfil vascular casts and conventional light microscopy histology of tissue sections. ..
  3. ENDOTHELIN IN HUMANS CORONARY IN EARLY ATHEROSCLEROSIS
    Amir Lerman; Fiscal Year: 2003
    ....
  4. Considerations of covariates in biomarker studies
    Margaret S Pepe; Fiscal Year: 2010
    ..Programs written in Stata will be made available through the Stata archive, the EDRN and through a 'Diagnostics and Biomarkers Statistical Center'web site. ..
  5. MRI-Guided Angioplasty of Renal Artery Stenosis
    Reed Omary; Fiscal Year: 2005
    ..MRI guidance will also avoid the ionizing radiation exposure of x-rays and the potential kidney toxicity of iodinated contrast agents. ..
  6. Coronary Endothelial Function in Humans
    Amir Lerman; Fiscal Year: 2006
    ..The success of this program has the potential to further both the research and mentoring endeavors of patient-oriented investigation and mentoring the next generation of patient-oriented researchers. ..
  7. Pyrophosphate in vascular calcification of renal failure
    W CHARLES O apos NEILL; Fiscal Year: 2010
    ..The results will establish a new paradigm for vascular calcification in renal failure and form the basis for important clinical trials in humans. ..
  8. Clinical Translational Research in Transplant Nephrology
    Bryan Becker; Fiscal Year: 2006
    ..It will also work to meet the NIH's goal of increasing the number of physician-scientists conducting high-quality patient-oriented research. ..
  9. Controlled-Release HIF-1 Delivery for Arteriogenesis
    Lawrence Hofmann; Fiscal Year: 2005
    ..These projects and career development plans will provide the resources, collaborative relationships, and academic foundation of which the candidate will build a successful career as an independent clinical scientist. ..
  10. E M Transdifferentiation in Proximal Tubule Cells
    Bryan Becker; Fiscal Year: 2004
    ..abstract_text> ..
  11. Renal Volume Measurement to Detect Early Kidney Disease
    W O NEILL; Fiscal Year: 2004
    ..abstract_text> ..
  12. Angiotensin II Receptor Blockade and Chronic Rejection
    Bryan Becker; Fiscal Year: 2003
    ....
  13. ECHOCARDIOGRAPHIC ASSESSMENT OF MICROVASCULAR PERFUSION
    Kevin Wei; Fiscal Year: 2003
    ....
  14. MOLECULAR REGULATION OF ENDOTHELIAL NA K 2CL COTRANSPORT
    W O NEILL; Fiscal Year: 2002
    ..abstract_text> ..