kidney calculi

Summary

Summary: Calculi occurring in the KIDNEY. Calculi too large to pass spontaneously range in size from 1 cm to the staghorn stones that occupy the renal pelvis and calyces.

Top Publications

  1. pmc Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases
    Daniel F Gudbjartsson
    deCODE Genetics, Reykjavik, Iceland
    PLoS Genet 6:e1001039. 2010
  2. ncbi Obesity, weight gain, and the risk of kidney stones
    Eric N Taylor
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 293:455-62. 2005
  3. ncbi Time trends in reported prevalence of kidney stones in the United States: 1976-1994
    Kiriaki K Stamatelou
    Renal Unit, Blue Cross Hospital, Athens, Greece
    Kidney Int 63:1817-23. 2003
  4. ncbi Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations
    Glenn M Preminger
    J Urol 173:1991-2000. 2005
  5. pmc Kidney stone disease
    Fredric L Coe
    Renal Section, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Invest 115:2598-608. 2005
  6. ncbi Laparoscopic pyeloplasty with concomitant pyelolithotomy
    Sanjay Ramakumar
    Section of Urology, Department of Surgery, University of Arizona, Tucson, Arizona, USA
    J Urol 167:1378-80. 2002
  7. ncbi The contemporary management of renal and ureteric calculi
    David J Galvin
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    BJU Int 98:1283-8. 2006
  8. ncbi Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density
    Gudmar Thorleifsson
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nat Genet 41:926-30. 2009
  9. pmc Epidemiology of stone disease
    Gary C Curhan
    Channing Laboratory and Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Urol Clin North Am 34:287-93. 2007
  10. pmc Three pathways for human kidney stone formation
    Fredric L Coe
    Department of Medicine, University of Chicago, Nephrology Section MC 5100, 5841 South Maryland Avenue, Chicago, IL, 60637, USA
    Urol Res 38:147-60. 2010

Detail Information

Publications281 found, 100 shown here

  1. pmc Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases
    Daniel F Gudbjartsson
    deCODE Genetics, Reykjavik, Iceland
    PLoS Genet 6:e1001039. 2010
    ..0064), and suggestively with gout. In contrast to CKD, the UMOD variant confers protection against kidney stones when studied in 3,617 Icelandic and Dutch kidney stone cases and 43,201 controls (OR = 0.88, P = 5.7 x 10(-5))...
  2. ncbi Obesity, weight gain, and the risk of kidney stones
    Eric N Taylor
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 293:455-62. 2005
    ..It is unclear if obesity increases the risk of stone formation, and it is not known if weight gain influences risk...
  3. ncbi Time trends in reported prevalence of kidney stones in the United States: 1976-1994
    Kiriaki K Stamatelou
    Renal Unit, Blue Cross Hospital, Athens, Greece
    Kidney Int 63:1817-23. 2003
    ..Study objective was to determine whether kidney stone disease prevalence increased in the United States over a 20-year period and the influence of region, race/ethnicity, and gender on stone disease risk...
  4. ncbi Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations
    Glenn M Preminger
    J Urol 173:1991-2000. 2005
  5. pmc Kidney stone disease
    Fredric L Coe
    Renal Section, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Invest 115:2598-608. 2005
    ....
  6. ncbi Laparoscopic pyeloplasty with concomitant pyelolithotomy
    Sanjay Ramakumar
    Section of Urology, Department of Surgery, University of Arizona, Tucson, Arizona, USA
    J Urol 167:1378-80. 2002
    ..We present our experience with laparoscopic pyeloplasty plus pyelolithotomy in patients in whom stones were not the cause of ureteropelvic junction obstruction...
  7. ncbi The contemporary management of renal and ureteric calculi
    David J Galvin
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    BJU Int 98:1283-8. 2006
  8. ncbi Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density
    Gudmar Thorleifsson
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nat Genet 41:926-30. 2009
    ..The same variants were also found to associate with reduced bone mineral density at the hip (P = 0.00039) and spine (P = 0.0077)...
  9. pmc Epidemiology of stone disease
    Gary C Curhan
    Channing Laboratory and Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Urol Clin North Am 34:287-93. 2007
    ..Because nephrolithiasis is a complex disease, an understanding of the epidemiology, particularly the interactions among different factors, may help lead to approaches that reduce the risk of stone formation...
  10. pmc Three pathways for human kidney stone formation
    Fredric L Coe
    Department of Medicine, University of Chicago, Nephrology Section MC 5100, 5841 South Maryland Avenue, Chicago, IL, 60637, USA
    Urol Res 38:147-60. 2010
    ..Although the final products may be very similar, the ways of creation are so different that in attempting to create animal and cell models of the processes one needs to be careful that the details of the human condition are included...
  11. ncbi Cooperation of phosphates and carboxylates controls calcium oxalate crystallization in ultrafiltered urine
    Bernd Grohe
    Department of Dentistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, N6A 5C1, Canada
    Urol Res 39:327-38. 2011
    ..Thus, we conclude that carboxylate groups play a primary role in inhibiting COM formation, but phosphate and carboxylate groups are both important in initiating and promoting COD formation...
  12. pmc Recent advances in the pathophysiology of nephrolithiasis
    Khashayar Sakhaee
    Department of Internal Medicine, Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 8885, USA
    Kidney Int 75:585-95. 2009
    ....
  13. ncbi Comparison of percutaneous nephrolithotomy and retrograde flexible nephrolithotripsy for the management of 2-4 cm stones: a matched-pair analysis
    Tolga Akman
    Department of Urology, Haseki Training and Research Hospital, Istanbul, Turkey
    BJU Int 109:1384-9. 2012
    ..This study shows that retrograde intrarenal surgery may be an alternative therapy to percutaneous nephrolithotomy, with acceptable efficacy and low morbidity for 2-4 cm stones...
  14. ncbi Role of renal epithelial cells in the initiation of calcium oxalate stones
    Saeed R Khan
    Department of Pathology, College of Medicine, University of Florida, Gainesville 32610 0275, USA
    Nephron Exp Nephrol 98:e55-60. 2004
    ..Extracellular environment changes from one that inhibits crystal nucleation, growth, aggregation and retention to that, which promotes these processes...
  15. ncbi Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation
    Yoshiro Suzuki
    Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland
    Hum Mol Genet 17:1613-8. 2008
    ..01 pmol/min/oocyte for ancestral versus derived haplotype, P < 0.01). These results suggest that the ancestral gain-of-function haplotype in TRPV6 plays a role in calcium stone formation in certain forms of absorptive hypercalciuria...
  16. ncbi Laparoscopic pyeloplasty with concomitant pyelolithotomy: technique and outcomes
    Robert J Stein
    Department of Urology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Endourol 22:1251-5. 2008
    ..We report our experience with laparoscopic pyelolithotomy at the time of laparoscopic pyeloplasty and compare outcome data with a cohort of patients undergoing laparoscopic pyeloplasty without coexistent stone disease...
  17. ncbi Essential arterial hypertension and stone disease
    L Borghi
    Institutes of Semeiotica Medica, University of Parma, Italy
    Kidney Int 55:2397-406. 1999
    ..Cross-sectional studies have shown that nephrolithiasis is more frequently found in hypertensive patients than in normotensive subjects, but the pathogenic link between hypertension and stone disease is still not clear...
  18. ncbi Twenty-four-hour urine chemistries and the risk of kidney stones among women and men
    G C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 59:2290-8. 2001
    ..Unfortunately, the majority of previous studies of 24-hour urine chemistries were limited by the inclusion of recurrent stone formers and poorly defined controls...
  19. ncbi Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation
    Lan Mo
    Department of Urology, Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, New York 10010, USA
    Kidney Int 66:1159-66. 2004
    ..Here we examined the role of Tamm-Horsfall protein (THP), the principal urinary protein, in urinary defense against renal calcium crystal formation, using a THP knockout model that we recently developed...
  20. ncbi Metabolic syndrome and self-reported history of kidney stones: the National Health and Nutrition Examination Survey (NHANES III) 1988-1994
    Bradford West
    Division of Nephrology, University of Arizona, Tucson, AZ 85724, USA
    Am J Kidney Dis 51:741-7. 2008
    ....
  21. ncbi Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up
    Eric N Taylor
    Department of Medicine, Channing Laboratory, Third Floor, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    J Am Soc Nephrol 15:3225-32. 2004
    ..Because age and body size affect the relation between diet and kidney stones, dietary recommendations for stone prevention should be tailored to the individual patient...
  22. ncbi Dietary factors and the risk of incident kidney stones in younger women: Nurses' Health Study II
    Gary C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Arch Intern Med 164:885-91. 2004
    ..Recently, phytate has been suggested to play a role in stone formation. To our knowledge, no prospective information on the role of dietary factors and risk of kidney stone formation is available in younger women...
  23. ncbi The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance
    Nicola Abate
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9169, USA
    Kidney Int 65:386-92. 2004
    ....
  24. ncbi Nephrolithiasis and osteoporosis associated with hypophosphatemia caused by mutations in the type 2a sodium-phosphate cotransporter
    Dominique Prie
    Service de Physiologie Explorations Fonctionnelles, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France
    N Engl J Med 347:983-91. 2002
    ..We hypothesized that mutations in the gene coding for the main renal sodium-phosphate cotransporter (NPT2a) may be present in patients with these disorders...
  25. ncbi Simple classification of renal calculi closely related to their micromorphology and etiology
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Balearic Islands, Ctra Valldemossa km 7 5, 07071 Palma de Mallorca, Spain
    Clin Chim Acta 322:29-36. 2002
    ..Classification of renal calculi with clear correlation with the main urinary etiological conditions has been previously established. However, such information is complex and difficult to adapt to clinical routine practice...
  26. pmc Kidney stones and the risk for chronic kidney disease
    Andrew D Rule
    Departments of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905
    Clin J Am Soc Nephrol 4:804-11. 2009
    ..Kidney stones lead to chronic kidney disease (CKD) in people with rare hereditary disorders (e.g., primary hyperoxaluria, cystinuria), but it is unknown whether kidney stones are an important risk factor for CKD in the general population...
  27. ncbi Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: osteopontin localization
    Andrew P Evan
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana 46220, USA
    Kidney Int 68:145-54. 2005
    ..Thus our purpose here is to detail the structure of the interstitial and membrane-bound plaque and explore the relationship of plaque apatite to osteopontin, a well-known crystal-associated urine protein...
  28. ncbi Effect of biomolecules from human renal matrix of calcium oxalate monohydrate (CaOx) stones on in vitro calcium phosphate crystallization
    Priyadarshini Pathak
    Jaypee University of Information Technology, Waknaghat, India
    Int Braz J Urol 36:621-8. 2010
    ....
  29. ncbi Urinary pH and stone formation
    Carsten A Wagner
    Institute of Physiology and Zurich Center for Integrative Human Physiology ZIHP, Zurich, University of Zurich, Switzerland
    J Nephrol 23:S165-9. 2010
    ..This review will discuss a few aspects that relate to the capacity of the kidney to regulate pH and its impact on the excretion of solutes that participate in the formation or prevention of stones...
  30. ncbi Body size and 24-hour urine composition
    Eric N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Kidney Dis 48:905-15. 2006
    ..Greater body mass index (BMI) is a risk factor for kidney stones. However, the relation between BMI and the urinary excretion of many lithogenic factors remains unclear...
  31. pmc Laparoscopic pyeloplasty and flexible nephroscopy: simultaneous treatment of ureteropelvic junction obstruction and nephrolithiasis
    Adam J Ball
    Department of Urology, University of Miami School of Medicine, Miami, FL 33101, USA
    JSLS 8:223-8. 2004
    ..Therapeutic controversy exists regarding their ideal management. We report our use of flexible nephroscopy during laparoscopic pyeloplasty for caliceal stone removal...
  32. ncbi Characterization of Tamm-Horsfall protein in a rat nephrolithiasis model
    J A Gokhale
    Department of Pathology, University of Florida, Gainesville, USA
    J Urol 166:1492-7. 2001
    ....
  33. ncbi Morphological conversion of calcium oxalate crystals into stones is regulated by osteopontin in mouse kidney
    Atsushi Okada
    Department of Nephrourology, Nagoya City University Graduate School of Medical Sciences, Mizuho cho, Mizuho ku, Nagoya City, Aichi, Japan
    J Bone Miner Res 23:1629-37. 2008
    ..Immunohistochemical staining of OPN showed that the WT crystals contained OPN protein but not KO crystals. We concluded that OPN plays a crucial role in the morphological conversion of calcium oxalate crystals to stones in mouse kidneys...
  34. ncbi Role of sex hormones in experimental calcium oxalate nephrolithiasis
    J Fan
    Urolithiasis Research Laboratory, Division of Urology, University of Colorado Health Sciences Center, Denver 80262, USA
    J Am Soc Nephrol 10:S376-80. 1999
    ..These findings may partly explain why nephrolithiasis is a predominantly male disease...
  35. ncbi Mechanisms mediating oxalate-induced alterations in renal cell functions
    Julie A Jonassen
    Department of Physiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Crit Rev Eukaryot Gene Expr 13:55-72. 2003
    ....
  36. pmc Superoxide from NADPH oxidase as second messenger for the expression of osteopontin and monocyte chemoattractant protein-1 in renal epithelial cells exposed to calcium oxalate crystals
    Tohru Umekawa
    Department of Urology, Kinki University School of Medicine, Osaka, Japan
    BJU Int 104:115-20. 2009
    ....
  37. ncbi Crystal retention capacity of cells in the human nephron: involvement of CD44 and its ligands hyaluronic acid and osteopontin in the transition of a crystal binding- into a nonadherent epithelium
    Anja Verhulst
    Department of Nephrology Hypertension, University of Antwerp, Antwerp, Belgium
    J Am Soc Nephrol 14:107-15. 2003
    ....
  38. ncbi Association between vitamin D receptor gene polymorphism and nephrolithiasis
    M Ruggiero
    Institute of General Pathology, University of Florence, Italy
    Miner Electrolyte Metab 25:185-90. 1999
    ..To study the distribution of vitamin D receptor (VDR) gene alleles in hypercalciuric and nonhypercalciuric nephrolithiasis patients, hypothesizing that distinct biochemical parameters would be associated with different VDR genotypes...
  39. ncbi Kidney stones: pathophysiology and medical management
    Orson W Moe
    Charles and Jane Pak Center of Mineral Metabolism and Clinical Research and Department of Internal Medicine University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Lancet 367:333-44. 2006
    ..Manipulation of inhibitors and epithelial factors is important and needs further investigation. Advances in the management of nephrolithiasis depend on combined efforts of clinicians and scientists to understand the pathophysiology...
  40. ncbi Beneficial effect of vitamin E supplementation on the biochemical and kinetic properties of Tamm-Horsfall glycoprotein in hypertensive and hyperoxaluric patients
    Kamalanathan Sumitra
    Department of Medical Biochemistry, Dr ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Taramani, Chennai, Tamilnadu, India, PIN 600 113
    Nephrol Dial Transplant 20:1407-15. 2005
    ..This study aimed to assess the therapeutic efficacy of oral vitamin E supplementation on the biochemical and kinetic properties of Tamm-Horsfall glycoprotein (THP) in hypertensive and hyperoxaluric patients...
  41. pmc The association of increasing body mass index and kidney stone disease
    Michelle J Semins
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Urol 183:571-5. 2010
    ..However, the effect of increasing degrees of obesity on stone formation has yet to be defined. To address this question we examined how an increasing body mass index affects the risk of kidney stone disease...
  42. ncbi Use of ureteral stent in extracorporeal shock wave lithotripsy for upper urinary calculi: a systematic review and meta-analysis
    Pengfei Shen
    Department of Urology, West China Hospital, Sichuan University, Chengdu, China
    J Urol 186:1328-35. 2011
    ..This systematic review was performed to assess the necessity and complications of stenting before extracorporeal shock wave lithotripsy in the management of upper urinary stones...
  43. ncbi Minipercutaneous nephorlithotomy
    M Monga
    Division of Urology, University of California, San Diego 92103 8897, USA
    J Endourol 14:419-21. 2000
    ..To evaluate the safety and efficacy of a minipercutaneous nephrolithotomy procedure (mini-PCNL) through a 20F sheath...
  44. ncbi An oxalate-binding protein with crystal growth promoter activity from human kidney stone matrix
    A Govindaraj
    Department of Medical Biochemistry, Dr A L M PG Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, India
    BJU Int 90:336-44. 2002
    ..To fractionate renal-stone matrix proteins, identify the presence of oxalate-binding protein and assess its effect in a calcium oxalate (CaOx) crystal growth system...
  45. ncbi The impact of cystinuria on renal function
    Dean G Assimos
    Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Urol 168:27-30. 2002
    ..We determined the potential impact of cystinuria and cystine stone formation on the level of renal function compared to calcium oxalate stone formers...
  46. ncbi Role of laparoscopy in management of renal stones: single-center experience and review of literature
    Thiagarajan Nambirajan
    Department of Urology, Elisabethinen Hospital, Linz, Austria
    J Endourol 19:353-9. 2005
    ..Laparoscopy can be an alternative modality in the management of renal stones. We present our experience with laparoscopic renal stone surgery...
  47. ncbi Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: a 3-mo randomized controlled trial
    Antonio Nouvenne
    Department of Clinical Sciences, University of Parma, Parma, Italy
    Am J Clin Nutr 91:565-70. 2010
    ....
  48. ncbi Treatment outcomes after endopyelotomy performed with or without simultaneous nephrolithotomy: 10-year experience
    Douglas S Berkman
    Department of Urology, Columbia University, College of Physicians and Surgeons, New York, New York, USA
    J Endourol 23:1409-13. 2009
    ..This study intends to determine if stone extraction performed with EP increases failure rate...
  49. ncbi [Percutaneous kidney lithotripsy. Clinical course, indications, and current methodology in our Lithotripsy Unit]
    G Ibarluzea González
    Unidad de Litotricia, Hospital de Galdacano, Usansolo, Vizcaya, Espana
    Arch Esp Urol 54:951-69. 2001
    ..To review the history, development, indications and current methods of percutaneous renal lithotripsy...
  50. ncbi Management of the staghorn calculus: multiple-tract versus single-tract percutaneous nephrolithotomy
    Arvind P Ganpule
    Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India
    Curr Opin Urol 18:220-3. 2008
    ..The debate continues over the use of single tract versus multiple tract percutaneous nephrolithotomy. We review papers on the topic published over the past 12-24 months...
  51. pmc Proteomic evaluation of biological nanoparticles isolated from human kidney stones and calcified arteries
    Farooq A Shiekh
    Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Acta Biomater 6:4065-72. 2010
    ..These elements, including EF-Tu, can be used as biomarkers to further define the processes that mediate propagation of biological NPs and their contribution to disease...
  52. ncbi Multi-tract percutaneous nephrolithotomy for large complete staghorn calculi
    Monish Aron
    Department of Urology, All India Institute of Medical Sciences, New Delhi, India
    Urol Int 75:327-32. 2005
    ..We present data to support multi-tract PCNL for large (surface area >3,000 mm(2)) complete staghorn calculi...
  53. pmc Robot-assisted laparoscopic pyeloplasty with stone removal in an ectopic pelvic kidney
    Rishi Nayyar
    Department of Urology, All India Institute of Medical Sciences, New Delhi, India
    JSLS 14:130-2. 2010
    ..Here, we present successful management using the robotic technique of one such case of concomitant pyeloplasty and pyelolithotomy...
  54. ncbi Single upper-pole percutaneous access for treatment of > or = 5-cm complex branched staghorn calculi: is shockwave lithotripsy necessary?
    Carson Wong
    Department of Urology, University of Miami, 1400 NW 10th Avenue, Suite No 507, Miami, FL 33126, USA
    J Endourol 16:477-81. 2002
    ..We believe these stones can often be removed with a staged procedure via a single upper-pole percutaneous access using flexible nephroscopy and the holmium:YAG laser. Our experience is reviewed...
  55. ncbi Comparison of 150 simultaneous bilateral and 300 unilateral percutaneous nephrolithotomies
    Endre Holman
    Semmelweis Hospital Department of Urology, Kiskunhalas, Hungary
    J Endourol 16:33-6. 2002
    ..To compare the results, complications, efficiency, and safety of simultaneous bilateral percutaneous nephrolithotomy (SBPN) and unilateral percutaneous nephrolithotomy (PCNL)...
  56. ncbi [Cultivation and morphology of nanobacteria in sera of patients with kidney calculi]
    Liang Chen
    Department of Urology, Peking University People s Hospital, Beijing 100034, China
    Beijing Da Xue Xue Bao 42:443-6. 2010
    To detect, culture, and characterize the nanobacteria (NB) from sera of patients with kidney calculi in our department.
  57. ncbi Lipid peroxidation and its correlations with urinary levels of oxalate, citric acid, and osteopontin in patients with renal calcium oxalate stones
    Ho Shiang Huang
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Urology 62:1123-8. 2003
    ..We also used the isoenzymes of glutathione S-transferase (GST) to examine which parts of the renal tubules were injured in patients with renal stones...
  58. ncbi Nephrolithiasis in children
    Mary Ann Cameron
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8885, USA
    Pediatr Nephrol 20:1587-92. 2005
    ..Environmental and hereditary factors are summarized to provide a guide in the evaluation of pediatric stone formers...
  59. ncbi Aggressive approach to staghorn calculi-safety and efficacy of multiple tracts percutaneous nephrolithotomy
    Manish Singla
    Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Urology 71:1039-42. 2008
    ..To evaluate the safety and efficacy of an aggressive approach to staghorn calculi using multiple-tract percutaneous nephrolithotomy...
  60. ncbi ESRD caused by nephrolithiasis: prevalence, mechanisms, and prevention
    Paul Jungers
    Department of Nephrology Necker Hospital, Paris, France
    Am J Kidney Dis 44:799-805. 2004
    ..The contribution of nephrolithiasis-related end-stage renal disease (ESRD) to patients requiring renal replacement therapy has never been specifically evaluated...
  61. ncbi Phytate acts as an inhibitor in formation of renal calculi
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Front Biosci 12:2580-7. 2007
    ..The findings show that the action of phytate as a crystallization inhibitor takes place both in the intrapapillary tissue and urine...
  62. ncbi Etiological role of estrogen status in renal stone formation
    Howard J Heller
    Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Center for Mineral Metabolism and Clinical Research, USA
    J Urol 168:1923-7. 2002
    ..We examined the contribution of estrogen to kidney stone risk by comparing outpatient evaluations in the 2 genders, and in estrogen treated and untreated postmenopausal women...
  63. pmc Diagnosis, treatment and follow-up of 25 patients with melamine-induced kidney stones complicated by acute obstructive renal failure in Beijing Children's Hospital
    Qiang Sun
    Department of Nephrology, Beijing Children s Hospital Affiliated to Capital Medical University, Beijing, China, 100045
    Eur J Pediatr 169:483-9. 2010
    ..Providing liquid orally or intravenously plus alkalisation of urine proved to promote the removal of the stones. Follow-up of 12 to 17 months after discharge showed no sequelae...
  64. pmc Physiopathology and etiology of stone formation in the kidney and the urinary tract
    Andrew P Evan
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Ms 5055, Indianapolis, IN 46220, USA
    Pediatr Nephrol 25:831-41. 2010
    ....
  65. ncbi Pathophysiologic basis for normouricosuric uric acid nephrolithiasis
    Khashayar Sakhaee
    Center of Mineral Metabolism and Clinical Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8891, USA
    Kidney Int 62:971-9. 2002
    ..Patients with uric acid nephrolithaisis have normal acid-base parameters according conventional clinical tests...
  66. ncbi The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease
    Willy Günther
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Falkenried 94, 20246 Hamburg, Germany
    Pflugers Arch 445:456-62. 2003
    ..We discuss how the primary defect in endocytosis leads via secondary changes in calciotropic hormones to the tertiary symptoms hyperphosphaturia, hypercalciuria and kidney stones...
  67. ncbi Management of lower pole renal calculi: shock wave lithotripsy versus percutaneous nephrolithotomy versus flexible ureteroscopy
    Glenn M Preminger
    The Comprehensive Kidney Stone Center, The Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Urol Res 34:108-11. 2006
    ..If the stone cannot be fragmented in situ, nitinol basket or grasper retrieval, through a fully deflected ureteroscope, allows for repositioning of the stone into a less dependant position, thus facilitating stone fragmentation...
  68. ncbi Association of urinary pH with body weight in nephrolithiasis
    Naim M Maalouf
    Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Kidney Int 65:1422-5. 2004
    ..Based on these observations, we hypothesized that urinary pH may be inversely associated to body weight in nephrolithiasis...
  69. ncbi Minimally invasive PCNL in patients with renal pelvic and calyceal stones
    S Lahme
    Department of Urology, University of Tubingen, Germany
    Eur Urol 40:619-24. 2001
    ..MPCNL is not suitable for large concrements since the limited sheath diameter would increase the operating time. Due to this limitation, MPCNL represents an extension of the indication for conventional PCNL that it can in no way replace...
  70. ncbi A single 24-hour urine collection is inadequate for the medical evaluation of nephrolithiasis
    Joan H Parks
    Nephrology Section, University of Chicago and LithoLink Corp, Chicago, Illinois, USA
    J Urol 167:1607-12. 2002
    ..We determined the adequacy of a single 24-hour urine sample for evaluating patients for medical renal stone prevention...
  71. ncbi [Composition of renal stones currently observed in non-industrialized countries]
    Michel Daudon
    Laboratoire Cristal, Service de Biochimie A, Hopital Necker, Paris, France
    Prog Urol 14:1151-61. 2004
    ..To verify whether this difference in the epidemiological profile is still observed today, we analysed renal stones collected in various regions of the globe and compared their composition to that of stones observed in France...
  72. ncbi Metabolic risk factors in children with kidney stone disease
    Francisco R Spivacow
    Instituto de Investigaciones Metabólicas, Universidad del Salvador, Buenos Aires, Argentina
    Pediatr Nephrol 23:1129-33. 2008
    ..Very often there is a positive family history of renal stone disease in first- and second-degree relatives...
  73. ncbi Genetics and calcium nephrolithiasis
    Giuseppe Vezzoli
    Nephrology and Dialysis Unit, San Raffaele Scientific Institute, Via Olgettina 60, Milan, Italy
    Kidney Int 80:587-93. 2011
    ..Technological skills, accurate clinical examination, and a detailed phenotype description are the basis to get new insight about the genetic basis of nephrolithiasis...
  74. ncbi Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans
    Ching Wan Lam
    Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Clin Chim Acta 402:150-5. 2009
    ..An epidemic of urinary stones affecting children after consumption of melamine tainted milk is unfolding. We defined clinicopathological features of the disease for diagnosis, monitoring, and treatment of this group of patients...
  75. ncbi Prospective randomized trial of three different methods of nephrostomy tract closure after percutaneous nephrolithotripsy
    Roger Li
    Department of Urology, University of California, Irvine School of Medicine, Orange, CA, USA
    BJU Int 107:1660-5. 2011
    ..To evaluate the safety and efficacy of 'tubeless' nephrostomy tract closure in reducing postoperative morbidity after percutaneous nephrolithotomy (PCNL)...
  76. ncbi The effectiveness of shock wave lithotripters: a case matched comparison
    Shaheen Alanee
    Urologic Surgery Department, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Urol 184:2364-7. 2010
    ..We compared the results of shock wave lithotripsy with a newer electromagnetic lithotripter to those of an electrohydraulic lithotripter using identical treatment and followup criteria...
  77. ncbi The beneficial effect of cynodon dactylon fractions on ethylene glycol-induced kidney calculi in rats
    Abolfazl Khajavi Rad
    Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
    Urol J 8:179-84. 2011
    To assess the beneficial effect of different fractions of Cynodon dactylon (C. dactylon) on ethylene glycol-induced kidney calculi in rats.
  78. ncbi Laparoscopic pyeloplasty with concomitant pyelolithotomy--is it an effective mode of treatment?
    Aneesh Srivastava
    Department of Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Urol Int 80:306-9. 2008
    ..Pelviureteric junction (PUJ) obstruction and concomitant renal calculus disease may coexist. We present our experience with simultaneous laparoscopic pyeloplasty and pyelolithotomy in such patients...
  79. ncbi Crystal-associated nephropathy in patients with brushite nephrolithiasis
    Andrew P Evan
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana 46220, USA
    Kidney Int 67:576-91. 2005
    ..We contrasted these with biopsies of 15 calcium oxalate stone formers, three stone formers with intestinal bypass, and four normal subjects...
  80. ncbi Endoscopic stone surgery: minimizing the risk of post-operative sepsis
    Paramananthan Mariappan
    Department of Urology, Scottish Lithotriptor Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, Scotland, UK
    Curr Opin Urol 15:101-5. 2005
    ..We have reviewed recent literature with regards to pathogenesis, predictors of infected stones and prevention of urosepsis...
  81. ncbi Pathophysiology and management of infectious staghorn calculi
    Kelly A Healy
    Department of Urology, The Emory Clinic, Emory University School of Medicine, 1365 Clifton Rd, Suite B, Atlanta, GA 30322, USA
    Urol Clin North Am 34:363-74. 2007
    ..Considering the various modalities for staghorn disease, percutaneous nephrolithotomy should be the first-line treatment for most patients based on its superior efficacy and low morbidity...
  82. ncbi Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers
    Kristin J Bergsland
    Litholink Corp, 2250 W Campbell Park Dr, Chicago, IL 60612, USA
    Am J Physiol Renal Physiol 291:F530-6. 2006
    ..Variations in these proteins may serve as markers of stone disease activity or vulnerability to recurrence and may provide new insights into mechanisms of stone formation...
  83. ncbi Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in children with moderate-size kidney stones: results of multi-institutional analysis
    Berkan Resorlu
    Kecioren Training and Research Hospital, Department of Urology, Ankara, Turkey
    Urology 80:519-23. 2012
    ....
  84. ncbi Evidence suggesting a genetic contribution to kidney stone in northeastern Thai population
    Suchai Sritippayawan
    Division of Nephrology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Urol Res 37:141-6. 2009
    ..Genetic and genomic studies will be conducted to identify the genes associated with the disease...
  85. ncbi Renal cortical mitochondrial aconitase is regulated in hypo- and hypercitraturia
    J Z Melnick
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
    Kidney Int 54:160-5. 1998
    ..The present studies examined the regulation of mitochondrial aconitase (m-aconitase), the first step in mitochondrial citrate metabolism, in these conditions...
  86. ncbi [Calcium kidney stones. Diagnostic and preventive prospects]
    T Arcidiacono
    Unita di Nefrologia e Dialisi, Istituto Scientifico San Raffaele, Universita Vita Salute, Milano, Italy
    G Ital Nefrol 24:535-46. 2007
    ..However, the expectations of the scientific community are turned to the advances in genetics and to the findings of genetic studies, which may provide diagnostic tools and criteria to define the risk profile of the single individual...
  87. ncbi Management of staghorn calculus: single puncture with judicious use of the flexible nephroscope
    Steve K Williams
    Department of Urology, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Curr Opin Urol 18:224-8. 2008
    ..To focus on the technique and results of a single percutaneous puncture for the management of staghorn renal calculi...
  88. ncbi A woman with recurrent calcium phosphate kidney stones
    David S Goldfarb
    Nephrology Section, New York Harbor Department of Veterans Affairs Healthcare System, New York, NY 10010, USA
    Clin J Am Soc Nephrol 7:1172-8. 2012
    ..Thiazides lower urine calcium excretion and may help ensure the safety of citrate supplementation...
  89. ncbi Long-term effects of extracorporeal shock wave lithotripsy on renal function: our experience with 156 patients with solitary kidney
    Ahmed El-Assmy
    Urology Department, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt
    J Urol 179:2229-32. 2008
    ..Patients with a solitary kidney provide a unique opportunity to evaluate any clinically significant change in renal function...
  90. ncbi Minimally invasive percutaneous nephrolithotomy with multiple mini tracts in a single session in treating staghorn calculi
    Wen Zhong
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, 1 Kangda Road, Haizhu District, Guangzhou, 510230, China
    Urol Res 39:117-22. 2011
    ....
  91. ncbi Endoscopic combined intrarenal surgery in Galdakao-modified supine Valdivia position: a new standard for percutaneous nephrolithotomy?
    Cesare M Scoffone
    Department of Urology, University of Turin, San Luigi Hospital, Orbassano Turin, Italy
    Eur Urol 54:1393-403. 2008
    ..It allows simultaneous performance of PCNL and retrograde ureteroscopy (ECIRS, Endoscopic Combined Intra-Renal Surgery) and has unquestionable anaesthesiological advantages...
  92. ncbi Changes in stone composition according to age in Tunisian pediatric patients
    Akram Alaya
    Department of Biochemistry and Toxicology, University Hospital, 5000 Monastir, Tunisia
    Int Urol Nephrol 42:621-8. 2010
    ..The increase in calcium oxalate stone in school age children and the decrease in struvite and purine stones confirm the change on the etiology of urolithiasis according to age...
  93. ncbi Influence of gender and age on calcium oxalate crystal growth inhibition by urine from relatives of stone forming patients
    Kristin J Bergsland
    University of Chicago and LithoLink Corp, Chicago, Illinois, USA
    J Urol 167:2372-6. 2002
    ..We define the relationships between urine inhibition of calcium oxalate crystal growth and age, gender, urine chemistries and stone formation among relatives of calcium stone forming patients...
  94. ncbi Percutaneous lithotripsy in Valdivia-Galdakao decubitus position: our experience
    Francisco Daels
    Department of Urology, Hospital Italiano, Buenos Aires, Argentina
    J Endourol 23:1615-20. 2009
    ....
  95. ncbi Extraperitoneal laparoscopy-assisted percutaneous nephrolithotomy in a left pelvic kidney
    Scott A Troxel
    Department of Urology, University of California Davis Medical Center, 4860 Y Street, Suite 3500, Sacramento, CA 95817, USA
    J Endourol 16:655-7. 2002
    ..Treatment of urolithiasis within a pelvic kidney presents a technical challenge. We report an extraperitoneal laparoscopy-assisted percutaneous approach to access the lower-pole calix of a pelvic kidney for percutaneous nephrolithotomy...
  96. ncbi Acute renal colic: value of unenhanced spiral computed tomography compared with intravenous urography
    S K Wong
    Department of Diagnostic Radiology, Singapore General Hospital, Outram Road, Singapore 169608
    Ann Acad Med Singapore 30:568-72. 2001
    ..CT is also useful in detecting secondary signs of obstruction even in the absence of any calculus...
  97. ncbi Rhazes, a genius physician in diagnosis and treatment of kidney calculi in medical history
    Saeed Changizi Ashtiyani
    Department of Physiology, Arak University of Medical Sciences, Arak, Iran
    Iran J Kidney Dis 4:106-10. 2010
    ..He also purposed and developed methods for diagnosis and treatment of kidney calculi for the first time in medical history...
  98. ncbi Laparoscopic pyelolithotomy--a technique for the management of stones in the ectopic pelvic kidney
    Nagesh Kamat
    Department of Urology, Kamats Kidney Hospital, Kothi, Gujarat, India
    Int J Urol 11:581-4. 2004
    We present our preliminary experience with the technique of laparoscopic pyelolithotomy for ectopic pelvic kidney calculi. This surgery has low morbidity and is ideally suited for the ectopic pelvic kidney with a laterally or anteriorly ..
  99. ncbi Outcomes of percutaneous nephrolithotomy in patients with solitary kidneys: a single-center experience
    Tolga Akman
    Haseki Training and Research Hospital, Department of Urology, Istanbul, Turkey
    Urology 78:272-6. 2011
    ..To evaluate the outcomes, complications, and early and late postoperative kidney function of percutaneous nephrolithotomy (PCNL) in patients with solitary kidneys...
  100. ncbi Prothrombin haplotype associated with kidney stone disease in Northeastern Thai patients
    Nanyawan Rungroj
    Division of Medical Molecular Biology, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Urology 77:249.e17-23. 2011
    ..To evaluate genetic variations associated with kidney stone disease in Northeastern Thai patients...
  101. ncbi Tubeless procedure is most important factor in reducing length of hospitalization after percutaneous nephrolithotomy: results of univariable and multivariable models
    Tolga Akman
    Haseki Training and Research Hospital, Department of Urology, Istanbul, Turkey
    Urology 77:299-304. 2011
    ..Recently, increases in healthcare costs have highlighted the importance of evaluating the cost effectiveness of a treatment as much as its efficacy...

Research Grants63

  1. Chronic Kidney Disease with Benign Prostatic Hyperplasia
    ANDREW RULE; Fiscal Year: 2004
    ..Based on preliminary data, a significant association between BPH surrogate measures and CKD is expected. This study will clarify whether earlier assessment and intervention in BPH is warranted to prevent CKD. ..
  2. Vocabulary Support for Consumer Health Informatics
    Qing Zeng; Fiscal Year: 2010
    ..and the foot in UMLS, although it refers to the entire lower limb in lay language;(c) the terms "Pes" and "Kidney Calculi" are much less intelligible to lay persons than their synonyms "foot" and "Kidney stone", yet few vocabularies ..
  3. Risk for Renal Injury Caused by Shock Wave Lithotripsy
    Andrew Evan; Fiscal Year: 2008
    ..All of these proposed studies aim at understanding the adverse effects of shock waves and advancing the safety of all stone patients at a time when reports of adverse effects in SWL are on the rise. ..
  4. IKSI: 2nd International Urolithiasis Research Symposium
    Andrew Evan; Fiscal Year: 2008
    ..This assumption was supported by the great success of the 1st International Urolithiasis Research symposium and the high level of interest in the 2nd symposium date. [unreadable] [unreadable] [unreadable]..
  5. TEM with Digital and Cryopreparation Systems
    Andrew Evan; Fiscal Year: 2003
    ..Dr. Richard Gregory will employ immunohistochemistry to examine the role of a Streptococcus mutans 65 kDa fimbrial protein binding as a mechanism for the induction of dental carries. ..
  6. IKSI: 1st Annual International Urolithiasis Research Symposium
    Andrew Evan; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  7. Novel Risk Factors for Kidney Stone Formation
    Eric Taylor; Fiscal Year: 2008
    ..At the completion of this career development award, Dr. Taylor will have a unique combination of skills and experience that will enable him to succeed as an independent clinical investigator. ..
  8. CaP, crystal responsible for idiopathic nephrolithasis
    Saeed Khan; Fiscal Year: 2008
    ..Type density and size must conform to limits and specifications provided in the PHS 398Instructions. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  9. TISSUE-CRYSTAL INTERACTION CA OXALATE NEPHROLITHIASIS
    Saeed Khan; Fiscal Year: 2003
    ..We can follow various events of nephrolithiasis in the animal model and cats explore the outcome of renal epithelial cell exposure to oxalate and calcium oxalate crystals in the cell cultures. ..
  10. EFFECTS OF ACID ON BONE
    David A Bushinsky; Fiscal Year: 2010
    ..The current proposal is aimed at understanding the first steps by which acid is detected by bone cells. Understanding the process by which the bone detects and neutralizes the acid can lead to an improvement in bone health. ..
  11. DIET SALT, CALCIUM KIDNEY STONES, BONE IN STONE FORMERS
    Linda Massey; Fiscal Year: 2001
    ..Reduction of dietary NaC1 from typical intakes of 200 mmol/day to an intake of 50 mmol/day may decrease the risk of recurrence of calcium-containing kidney stones and slow rates of bone loss, thus reducing risk of osteoporosis as well. ..
  12. ENDOGENOUS AND EXOGENOUS IL 10 AND RENAL INJURY
    Orson Moe; Fiscal Year: 2001
    ....
  13. Role of Nanobacteria in Human Calcifying Disease
    JOHN LIESKE; Fiscal Year: 2004
    ..abstract_text> ..
  14. NOVEL INHIBITOR OF CRYSTAL ADHESION TO RENAL CELLS
    JOHN LIESKE; Fiscal Year: 2004
    ..Achieving these specific aims will provide new knowledge about mechanisms that mediate stone formation, and provide a rational basis for design of novel strategies to treat and/or prevent this disease. ..
  15. FORMULATION OF RATIONAL THERAPY OF NEPHROLITHIASIS
    Orson Moe; Fiscal Year: 2008
    ..This proposal will address the nature of calcium-oxalate interaction and how it impacts on the risk of developing kidney stones. ..
  16. STRETCH-INDUCED CYCLOOXYGENASE-2 IN UROTHELIAL CELLs
    Stephen Nakada; Fiscal Year: 2005
    ..abstract_text> ..
  17. Acute Regulation of the Renal Na/H Exchanger NHE-3
    Orson Moe; Fiscal Year: 2005
    ..These studies will uncover highly fundamental mechanisms of regulation of an important epithelial Na transporter and further our understanding 01 disturbance in acid-base balance, Na retention and hypertension. ..
  18. Nephrolithiasis and Chronic Kidney Disease
    JOHN LIESKE; Fiscal Year: 2007
    ..This will gain additional urgency if in fact we demonstrate that NL is a significant risk factor for CKD. [unreadable] [unreadable] [unreadable]..
  19. Use of symbiotics to reduce urinary oxalate excretion
    JOHN LIESKE; Fiscal Year: 2007
    ..If results are positive, treatment for calcium oxalate kidney stones could be revolutionized. ..
  20. Oxalate-Induced Renal Scarring and Crystal Retention
    JOHN LIESKE; Fiscal Year: 2003
    ..Dr. Luis Juncos has extensive experience studying the regulation of renal blood flow in vivo, and will be critical in our efforts to develop the constant infusion model of hyperoxalemia and hyperoxaluria. ..
  21. H+-ATPase B-subunit Dysfunction and Calcium Nephrolithiasis
    Orson W Moe; Fiscal Year: 2010
    ....
  22. Osteoporosis in Hypercalciuric Kidney Stone Formers
    John Asplin; Fiscal Year: 2003
    ..We hope to use the algorithm developed in this research to expand out services to include bone disease management in kidney stone forming patients and their families. ..
  23. PROTEIN-MINERAL INTERACTIONS AND CALCIUM OXALATE STONES
    ROSEMARY RYALL; Fiscal Year: 2008
    ..abstract_text> ..
  24. Treatment of Calcium Nephrolithiasis Sodium Thiosulfate
    John Asplin; Fiscal Year: 2006
    ..New, more effective and better tolerated drugs are needed to reduce the recurrence of kidney stones in these patients. [unreadable] [unreadable] [unreadable]..
  25. RENAL CRYSTAL GROWTH INHIBITOR PROTEINS
    JACK KLEINMAN; Fiscal Year: 2002
    ....
  26. Bone-Sparing by Ca Salts With & Without Extra Phosphorus
    Robert Heaney; Fiscal Year: 2008
    ..1 Description, ..
  27. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2006
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..
  28. PHYSICAL MECHANISMS OF TISSUE DAMAGE IN SWL
    James McAteer; Fiscal Year: 2003
    ..abstract_text> ..
  29. BONY EFFECTS OF TRANSIENT NONSKELETAL ILLNESS
    Robert Heaney; Fiscal Year: 2001
    ....
  30. Risk Factors for Decline in Renal Function
    Gary Curhan; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  31. MECHANISMS OF INTESTINAL IRON ABSORPTION
    Matthias Hediger; Fiscal Year: 2004
    ....
  32. Prevention of Kidney Stone Crystal Retention
    Jack G Kleinman; Fiscal Year: 2010
    ..Should any of them be suitably free of toxicity, Phase I testing in human would be contemplated, presumably by a licensee. ..
  33. 10th International Symposium on Urolithiasis
    GLENN PREMINGER; Fiscal Year: 2004
    ..It is hoped that the cross fertilization of ideas and the development of new collaborations will foster new insights into the disease processes involved. ..
  34. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 2002
    ....
  35. Targeting Bone Remodeling For the Treatment of Osteoporosis
    John Bilezikian; Fiscal Year: 2008
    ..The purpose of this meeting is to bring together experts from these interdisciplinary fields so as to define the direction of the future. ..
  36. UROLITHIASIS AND PEROXIDATIVE INJURY
    Sivagnanam Thamilselvan; Fiscal Year: 2008
    ..These studies will provide valuable information on the importance of antioxidants and, whether antioxidants offer promise as a therapeutic agent for recurrent stone formers. ..
  37. Bladder-specific Knockout and Gene Expression
    Xue ru Wu; Fiscal Year: 2009
    ..These studies will generate powerful experimental tools for studying bladder biology and diseases and offer molecular insights regarding urothelial growth and tumorigenesis. ..
  38. Physical mechanisms of shock wave therapy in orthopedics
    THOMAS MATULA; Fiscal Year: 2010
    ..By understanding the basic science of shock wave interaction with bones and tissues, we will be able to provide recommendations to physicians on how to optimize their treatments of these conditions. ..
  39. Ultrasound contrast agent dynamics and vascular effects
    THOMAS MATULA; Fiscal Year: 2009
    ..These improvements will include a better diagnosis of medical problems, and therapeutic applications, such as delivery of drugs and medicine. ..
  40. Glyoxylate Reductase and Primary Hyperoxaluria
    Ross P Holmes; Fiscal Year: 2010
    ..These studies will increase our understanding of the metabolism associated with oxalate synthesis and will potentially identify novel therapeutic strategies to decrease oxalate synthesis in primary hyperoxaluria. ..
  41. Tamsulosin and steroids for urolithiasis
    Jeremy Brown; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  42. 11th International Symposium on Urolithiasis
    ROSS HOLMES; Fiscal Year: 2008
    ..Particular emphasis will be placed on using the financial support to assist new, young, female and minority researchers to attend the meeting. [unreadable] [unreadable] [unreadable]..
  43. Dietary Oxalate and Kidney Stone Formation
    DEAN GEORGE ASSIMOS; Fiscal Year: 2010
    ..This translation of laboratory based findings to the clinic should be adatable to reducing a number of dietary associated risk factors and in individuals with stones other than calcium oxalate. ..
  44. Prevention of Renal Damage in Primary Hyperoxaluria
    Dawn Milliner; Fiscal Year: 2008
    ..Clinical data, samples, and research protocols completed via the Registry will allow rapid testing of hypotheses and promote worldwide collaboration to advance the care of PH patients. ..
  45. Antiproliferative Rx for venous neointimal hyperplasia
    Prabir Roy Chaudhury; Fiscal Year: 2005
    ..We believe that the results from this study could transform the clinical care of hemodialysis patients and at the same time result in the successful clinical application of local therapy for the treatment of neointimal hyperplasia...
  46. Role of Biopolymers and Lipids in Kidney Stone Formation
    LAURIE GOWER; Fiscal Year: 2004
    ..The long-range clinical goal of this BRP is to provide a more effective means of diagnosis, treatment, and long-term prevention of renal calculi. ..
  47. 7th International Workshop on Primary Hyperoxaluria
    Dawn Milliner; Fiscal Year: 2005
    ..Recent crystallization of the AGT protein, and advances in the molecular genetics, diagnostic testing, and pharmacogenomics of PH make 2004 an exciting year for the 7th Workshop. ..
  48. REGULATION OF CITRATE TRANSPORT
    Lee Hamm; Fiscal Year: 2003
    ..abstract_text> ..
  49. SELECTIVE SODIUM-SENSITIVITY IN SALT-SENSITIVE BLACKS
    Ralph Morris; Fiscal Year: 2006
    ..5) The acute increases in plasma Na + concentration will predict the extent of acute increases in BP, RVR and TPR. ..
  50. Acupuncture and Low Back Pain during Pregnancy
    Shu Ming Wang; Fiscal Year: 2007
    ..abstract_text> ..
  51. SkyScan 1172 High-resolution desk-top micro-CT system
    James Williams; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  52. Dietary Protein Requirements in Hemodialysis Patients
    Joel Kopple; Fiscal Year: 2007
    ..Before and after these 5 months, total body protein will be assessed by TBNuf, body cell mass (TBK), and other components of body composition using anthropometry, DXA, and near infra-red interactance. ..
  53. Medicinal Plants of Antiquity: A Computerized Database
    Alain Touwaide; Fiscal Year: 2007
    ..These secondary databases will be linked to the primary database so that users of the primary database can consult at any moment the necessary information for a better understanding of ancient texts. [unreadable] [unreadable]..
  54. NOVEL REGULATORY MECHANISMS CONTROLLING BONE REPAIR AND OSTEOPOROSIS
    Peter Friedman; Fiscal Year: 2008
    ..The long-term objective is to identify novel compounds that can be used to treat post-menopausal osteoporosis. [unreadable] [unreadable] [unreadable]..
  55. Crystal Aggregation in Kidney Stone
    JEFFREY WESSON; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  56. THE ROLE OF ESTROGEN IN BONE METABOLISM
    ORHAN OZ; Fiscal Year: 2004
    ..abstract_text> ..
  57. Oxalate & Crystal Renal Phenotypes: A Microarray Study
    Susan Ruth Marengo; Fiscal Year: 2003
    ..The long term objective of this work is to establish the mechanism of oxalate induced damage in the kidney. ..
  58. Herbal Medicine Use in Minority Populations in the US
    David Kaufman; Fiscal Year: 2005
    ..Because the survey data are representative of the U.S. population, the results will provide a comprehensive and comparative picture of the use of non-vitamin/non-mineral dietary supplements in minority groups in this country. ..
  59. Continuous Treatment with Oxalate Changes Renal Physiology and Morphology (DK0750
    Susan Ruth Marengo; Fiscal Year: 2008
    ..The objective is to identify those effects which promote these conditions. Future work will determine the mechanism of these effects with the goal of developing an effective preventative therapy. [unreadable] [unreadable] [unreadable]..
  60. Oxalobacter Formigenes and Other Factors in Urolithiasis
    David Kaufman; Fiscal Year: 2005
    ..abstract_text> ..
  61. INTER ALPHA TRYPSIN INHIBITOR IN CAOX UROLITHIASIS
    Susan Ruth Marengo; Fiscal Year: 2002
    ..e. the liver the primary source of serum IaTI- trimer), or locally (kidney) as judged by Northern blot analysis of RNA message for each of the IaTI-subunits and by Western blot/ELISA of the protein. ..