hematuria

Summary

Summary: Presence of blood in the urine.

Top Publications

  1. ncbi The impact of biomarkers in multivariate algorithms for bladder cancer diagnosis in patients with hematuria
    Funso Abogunrin
    Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Ireland
    Cancer 118:2641-50. 2012
  2. ncbi The natural history of immunoglobulin a nephropathy among patients with hematuria and minimal proteinuria
    C C Szeto
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Am J Med 110:434-7. 2001
  3. ncbi The impact of a school health programme on the prevalence and morbidity of urinary schistosomiasis in Mwera Division, Pangani District, Tanzania
    P Magnussen
    Danish Bilharziasis Laboratory, Charlottenlund, Denmark
    Trans R Soc Trop Med Hyg 95:58-64. 2001
  4. ncbi Persistent asymptomatic isolated microscopic hematuria in Israeli adolescents and young adults and risk for end-stage renal disease
    Asaf Vivante
    Israeli Defense Forces Medical Corps and Talpiot Medical Leadership Program, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer 52621, Israel
    JAMA 306:729-36. 2011
  5. pmc Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra, Ghana
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, United Kingdom
    Am J Trop Med Hyg 80:435-41. 2009
  6. ncbi COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy
    Konstantinos Voskarides
    Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus
    J Am Soc Nephrol 18:3004-16. 2007
  7. ncbi A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    Dimitrios T Boumpas
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Arthritis Rheum 48:719-27. 2003
  8. ncbi Use of a multitarget fluorescence in situ hybridization assay to diagnose bladder cancer in patients with hematuria
    Michael F Sarosdy
    South Texas Urology and Urologic Oncology, 4499 Medical 218, San Antonio, TX 78229, USA
    J Urol 176:44-7. 2006
  9. ncbi MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness
    Marco Seri
    Laboratorio di Genetica Molecolare, Istituto G Gaslini, Genova, Italy
    Medicine (Baltimore) 82:203-15. 2003
  10. pmc Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees
    Yiannis Athanasiou
    Department of Nephrology, Nicosia General Hospital, Nicosia, Cyprus
    Clin J Am Soc Nephrol 6:1436-46. 2011

Detail Information

Publications263 found, 100 shown here

  1. ncbi The impact of biomarkers in multivariate algorithms for bladder cancer diagnosis in patients with hematuria
    Funso Abogunrin
    Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Ireland
    Cancer 118:2641-50. 2012
    ..aim was to determine whether single biomarkers and/or multivariate algorithms significantly improved on the predictive power of an algorithm based on demographics for prediction of urothelial cancer in patients presenting with hematuria.
  2. ncbi The natural history of immunoglobulin a nephropathy among patients with hematuria and minimal proteinuria
    C C Szeto
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Am J Med 110:434-7. 2001
    PURPOSE: To determine the natural history of immunoglobulin (Ig) A nephropathy among patients who presented with hematuria and minimal proteinuria, and factors associated with the development of adverse clinical events, such as ..
  3. ncbi The impact of a school health programme on the prevalence and morbidity of urinary schistosomiasis in Mwera Division, Pangani District, Tanzania
    P Magnussen
    Danish Bilharziasis Laboratory, Charlottenlund, Denmark
    Trans R Soc Trop Med Hyg 95:58-64. 2001
    ..Communities also participated in the improvement of sanitary installations at the schools...
  4. ncbi Persistent asymptomatic isolated microscopic hematuria in Israeli adolescents and young adults and risk for end-stage renal disease
    Asaf Vivante
    Israeli Defense Forces Medical Corps and Talpiot Medical Leadership Program, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer 52621, Israel
    JAMA 306:729-36. 2011
    Few data are available on long-term outcomes among adolescents and young adults with persistent asymptomatic isolated microscopic hematuria.
  5. pmc Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra, Ghana
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, United Kingdom
    Am J Trop Med Hyg 80:435-41. 2009
    ..haematobium eggs, dipsticks for detection of hematuria, tests for circulating antigens, antibody tests, and ultrasound scans of the urinary system...
  6. ncbi COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy
    Konstantinos Voskarides
    Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus
    J Am Soc Nephrol 18:3004-16. 2007
    ..found in approximately 40% of cases of thin basement membrane nephropathy, which is characterized by microscopic hematuria and is classically thought to cause proteinuria and chronic renal failure rarely...
  7. ncbi A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    Dimitrios T Boumpas
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Arthritis Rheum 48:719-27. 2003
    ..The primary outcome measure was 50% reduction in proteinuria without worsening of renal function...
  8. ncbi Use of a multitarget fluorescence in situ hybridization assay to diagnose bladder cancer in patients with hematuria
    Michael F Sarosdy
    South Texas Urology and Urologic Oncology, 4499 Medical 218, San Antonio, TX 78229, USA
    J Urol 176:44-7. 2006
    We evaluated the multitarget UroVysion fluorescence in situ hybridization assay for the diagnosis of bladder cancer in patients with hematuria and no history of bladder cancer.
  9. ncbi MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness
    Marco Seri
    Laboratorio di Genetica Molecolare, Istituto G Gaslini, Genova, Italy
    Medicine (Baltimore) 82:203-15. 2003
    ..Kidney abnormalities, such as hematuria and proteinuria, affected not only patients referred as Fechtner syndrome and Epstein syndrome but also those ..
  10. pmc Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees
    Yiannis Athanasiou
    Department of Nephrology, Nicosia General Hospital, Nicosia, Cyprus
    Clin J Am Soc Nephrol 6:1436-46. 2011
    ..CFHR5 nephropathy is clinically characterized by continuous microscopic hematuria whereas some patients present with additional episodes of synpharyngitic macrohematuria, associated with ..
  11. ncbi COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome
    Ilaria Longo
    Genetica Medica, Universita di Siena, Siena Dip Scienze Cliniche e Biologiche and Genetica, Biologia e Biochimica, Universita di Torino, Torino, Italy
    Kidney Int 61:1947-56. 2002
    COL4A3/COL4A4 mutations: From familial hematuria to autosomal-dominant or recessive Alport syndrome.
  12. ncbi Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria
    Konstantinos Voskarides
    Department of Biological Sciences, Molecular Medicine Research Center and Laboratory of Molecular and Medical Genetics, University of Cyprus, Kallipoleos 75, 1678 Nicosia, Cyprus
    Pediatr Nephrol 27:675-9. 2012
    Familial hematuria (FH) is associated with at least two pathological entities: thin basement membrane nephropathy (TBMN), caused by heterozygous COL4A3/COL4A4 mutations, and C3 nephropathy caused by CFHR5 mutations...
  13. ncbi Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney dis
    Alkis Pierides
    Department of Nephrology, Nicosia General Hospital, University of Cyprus, Cyprus
    Nephrol Dial Transplant 24:2721-9. 2009
    ..Heterozygous mutations in the COL4A3/ COL4A4 genes are currently thought to be responsible for familial benign microscopic haematuria and maintenance of normal long-term kidney function...
  14. ncbi Impact of clinical factors, including a point-of-care nuclear matrix protein-22 assay and cytology, on bladder cancer detection
    Yair Lotan
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 103:1368-74. 2009
    ..To determine whether the nuclear matrix protein-22 (NMP22) assay can improve the accuracy of discriminating between high-risk patients with and without bladder cancer...
  15. ncbi Diagnosis and management of superficial bladder cancer
    C L Amling
    Department of Urology, Naval Medical Center, San Diego, California, USA
    Curr Probl Cancer 25:219-78. 2001
    ..Gross or microscopic hematuria is the most common sign at presentation...
  16. pmc The role of molecular genetics in diagnosing familial hematuria(s)
    Constantinos Deltas
    Molecular Medicine Research Center and Laboratory of Molecular and Medical Genetics, Department of Biological Sciences, University of Cyprus, Kallipoleos 75, 1678 Nicosia, Cyprus
    Pediatr Nephrol 27:1221-31. 2012
    Familial microscopic hematuria (MH) of glomerular origin represents a heterogeneous group of monogenic conditions involving several genes, some of which remain unknown...
  17. ncbi Virtual cystoscopy of the contrast material-filled bladder in patients with gross hematuria
    Jeong Kon Kim
    Department of Radiology, Asan Medical Center, University of Ulsan, 388 1 Poongnap dong, Songpa Gu, Seoul, 138 736, South Korea
    AJR Am J Roentgenol 179:763-8. 2002
    The objective of this study was to evaluate the usefulness of virtual cystoscopy of the contrast material-filled bladder in evaluating patients with gross hematuria.
  18. ncbi A multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria
    Paul O'Sullivan
    Pacific Edge Ltd, Dunedin, New Zealand
    J Urol 188:741-7. 2012
    ....
  19. ncbi Mutations in the COL4A4 gene in thin basement membrane disease
    Mark Buzza
    University of Melbourne, Department of Medicine, Austin and Repatriation Medical Centre, Heidelberg, Australia
    Kidney Int 63:447-53. 2003
    Patients with thin basement membrane disease (TBMD) are often from families where hematuria segregates with the COL4A3 and COL4A4 genes. These genes also are affected in autosomal recessive Alport syndrome...
  20. ncbi Isolation and identification of potential urinary microparticle biomarkers of bladder cancer
    David M Smalley
    Mellon Medical Biomarker Discovery Laboratory, W M Keck Laboratory for Mass Spectrometry, Department of Urology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Proteome Res 7:2088-96. 2008
    ..Further studies will be needed to validate these potential biomarkers...
  21. pmc Familial hematuria
    Clifford E Kashtan
    Department of Pediatrics, Division of Pediatric Nephrology, University of Minnesota Medical School, University of Minnesota Children s Hospital, Fairview, Minneapolis, MN 55455, USA
    Pediatr Nephrol 24:1951-8. 2009
    b>Hematuria is a common presenting complaint in pediatric nephrology clinics and often has a familial basis...
  22. ncbi Urine erythrocyte morphology in patients with microscopic haematuria caused by a glomerulopathy
    Giovanni Battista Fogazzi
    Unità Operative di Nefrologia Laboratorio di ricerca sulle urine, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 15, Milano, Italy
    Pediatr Nephrol 23:1093-100. 2008
    ..4% and 85% for >or=5% acanthocytes/G1 cells and 12.2% and 100% for erythrocytic casts. Our findings demonstrate that the evaluation of UEM is useful to identify patients with an IMH of glomerular origin...
  23. ncbi Novel COL4A4 splice defect and in-frame deletion in a large consanguine family as a genetic link between benign familial haematuria and autosomal Alport syndrome
    Oliver Gross
    Medical Faculty University of Cologne, Cologne General Hospital, Department of Internal Medicine I, Merheim Medical Center, Cologne, Germany
    Nephrol Dial Transplant 18:1122-7. 2003
    ..The present study describes molecular changes of the COL4A4 gene that cause both diseases: autosomal recessive AS and BFH in a consanguine family with a 400-year-old history of haematuria...
  24. pmc BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants
    Peter H O'Donnell
    Section of Hematology Oncology, Department of Medicine, The University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637, USA
    Biol Blood Marrow Transplant 15:1038-1048.e1. 2009
    ..04). There was a direct relationship between blood and urine BKV levels and the occurrence, and degree, of hematuria (P < or = .03)...
  25. ncbi Microscopic hematuria and diabetic glomerulosclerosis--clinicopathological analysis of type 2 diabetic patients associated with overt proteinuria
    Tetsu Akimoto
    Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan
    Nephron Clin Pract 109:c119-26. 2008
    ..In addition, the prevalence and composition of nondiabetic renal disease (NDRD) among proteinuric diabetics still remain to be delineated...
  26. ncbi Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor?
    Yiu Tung Ip
    Department of Pathology, Queen Elizabeth Hospital, Hangzhou, Zhejiang, China
    Am J Surg Pathol 34:1695-700. 2010
    ..This report describes 2 cases of sporadic renal hemangioblastoma, with 1 patient presenting with hematuria and polycythemia, and the other low back pain...
  27. ncbi COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. glomerular epithelium destruction via basement membrane thinning?
    Konstantinos Voskarides
    Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus
    Connect Tissue Res 49:283-8. 2008
    ..Recently described mutations in collagen IV and laminin in patients with hematuria and severe nephrotic syndrome add to other experimental data supporting the hypothesis that the glomerular ..
  28. ncbi Prevalence and risk factors of chronic kidney disease: a population study in the Tibetan population
    Wei Chen
    Department of Nephrology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    Nephrol Dial Transplant 26:1592-9. 2011
    ..The prevalence of chronic kidney disease (CKD) at high altitude is not known. We conducted a population-based survey in Tibet to identify the prevalence and associated risk factors of CKD in subjects living at altitudes of > 3500 m...
  29. pmc Dense deposit disease: clinicopathologic study of 32 pediatric and adult patients
    Samih H Nasr
    Department of Pathology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Clin J Am Soc Nephrol 4:22-32. 2009
    ..Dense deposit disease (DDD) is a rare disorder that most commonly affects children. This study reports the largest North American series addressing clinicopathologic and outcome differences in children and adults...
  30. ncbi Sixteen novel mutations identified in COL4A3, COL4A4, and COL4A5 genes in Slovenian families with Alport syndrome and benign familial hematuria
    M Slajpah
    Department of Molecular Genetics, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Kidney Int 71:1287-95. 2007
    Alport syndrome (ATS) and benign familial hematuria (BFH) are type IV collagen inherited disorders...
  31. ncbi Tubular lesions determine prognosis of IgA nephropathy
    L Daniel
    Service d Anatomie Pathologique, C H U Timone, Marseille, France
    Am J Kidney Dis 35:13-20. 2000
    ..05) and proteinuria (P = 0.05). Hematuria was a protective factor (P = 0.03). Multivariate analysis showed that tubular grade 2 (relative risk [RR], 5...
  32. ncbi The BTA stat test is nonspecific for hematuria: an experimental hematuria model
    Omer Oge
    Department of Urolog, Adnan Menderes University School of Medicine, Aydin, Turkey
    J Urol 167:1318-9; discussion 1319-20. 2002
    An experimental hematuria model was designed to determine whether the bladder tumor antigen (BTA) stat test (Bion Diagnostics, Redmond, Washington) is influenced by microscopic or macroscopic hematuria.
  33. ncbi The clinical significance of asymptomatic gross and microscopic hematuria in children
    Jerry Bergstein
    Department of Pediatrics, Indiana University School of Medicine, and James Whitcomb Riley Hospital for Children, 699 West Drive, Rm 213, Indianapolis, IN 46202 5119, USA
    Arch Pediatr Adolesc Med 159:353-5. 2005
    The development of asymptomatic gross or microscopic hematuria is relatively common in children.
  34. ncbi Mutations in theCOL4A4 and COL4A3 genes cause familial benign hematuria
    Celia Badenas
    Nephrology and Genetics Departments, Hospital Clinic, Barcelona, Spain
    J Am Soc Nephrol 13:1248-54. 2002
    Familial benign hematuria (FBH) is a common autosomal dominant disorder characterized by the presence of persistent or recurrent hematuria...
  35. ncbi Transient IgA nephropathy with acute kidney injury in a patient with dengue fever
    Bala Krishna Upadhaya
    Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India
    Saudi J Kidney Dis Transpl 21:521-5. 2010
    ..Urine examination showed microscopic glomerular hematuria and proteinuria...
  36. ncbi Hematuria and proteinuria in a mass school urine screening test
    Yong Hoon Park
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea
    Pediatr Nephrol 20:1126-30. 2005
    A total of 1,044 school children identified with hematuria and/or proteinuria during a mass school urine screening test were referred to pediatric nephrologists at 13 hospitals in Korea. These children had isolated hematuria (IH) (60...
  37. ncbi [Modelling sensitivity, specificity and predictive values of hematuria testing using reagent sticks in the diagnosis of Schistosoma haematobium infection]
    J E Etard
    Institut de recherche et de développement IRD, BP 1386 Dakar, Senegal
    Bull Soc Pathol Exot 97:24-8. 2004
    ..A decrease in sensitivity adjusted for intensity of infection above 10 years of age among males is discussed. This modelling approach also uses all the information available and not only the data from the stratum of interest...
  38. ncbi Immunocytology in the assessment of patients with asymptomatic hematuria
    B J Schmitz-Dräger
    Urologie, EuromedClinic, Europa Allee 1, 90763 Fürth, Germany
    World J Urol 26:31-7. 2008
    Painless hematuria has remained a diagnostic challenge in daily urological practice. Key problem in the assessment of these patients is the discrimination between malignant and non-malignant conditions...
  39. pmc Benign familial hematuria due to mutation of the type IV collagen alpha4 gene
    H H Lemmink
    Department of Pediatrics, University Hospital Nijmegen, The Netherlands
    J Clin Invest 98:1114-8. 1996
    Benign familial hematuria (BFH) is characterized by autosomal dominant inheritance, thinning of the glomerular basement membrane (GBM) and normal renal function...
  40. pmc Urinary BTA: indicator of bladder cancer or of hematuria
    Makito Miyake
    Cancer Research Institute, MD Anderson Cancer Center Orlando, Orlando, FL 32827, USA
    World J Urol 30:869-73. 2012
    In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model.
  41. ncbi The clinical usefulness of nuclear matrix protein-22 in patients with end-stage renal disease and microscopic hematuria
    Brandon Trojan
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, Texas 79430 726, USA
    Ren Fail 35:72-6. 2013
    ..rate of the nuclear matrix protein-22 (NMP22) test in patients with end-stage renal disease (ESRD) and microscopic hematuria in order to avoid unnecessary follow-up tests for patients with false-positive NMP22 test results.
  42. ncbi Ultrastructural changes of glomerular basement membrane in IgA nephritis: relationship to hematuria
    T Taguchi
    , , Federal Republic of Germany
    Ultrastruct Pathol 12:17-26. 1988
    ..membrane (GBM) of 415 samples from 344 patients with IgA nephritis, were examined for potential relationship to hematuria. The GBM showed various alteration: splitting, thinning, membranolysis with swelling of the lamina rara externa ..
  43. pmc Prospective validation of a current algorithm including bedside US performed by emergency physicians for patients with acute flank pain suspected for renal colic
    M Kartal
    Emergency Department, Akdeniz University Hospital, Antalya, Turkey
    Emerg Med J 23:341-4. 2006
    ..Materials and..
  44. ncbi Emergency ultrasound and urinalysis in the evaluation of flank pain
    Romolo J Gaspari
    Department of Emergency Medicine, University of Massachusetts School of Medicine, Worcester, MA 01543, USA
    Acad Emerg Med 12:1180-4. 2005
    ..To determine the sensitivity and specificity of limited emergency ultrasonography of the kidney in diagnosing renal colic...
  45. ncbi Prevalence and factors associated with CKD: a population study from Beijing
    Luxia Zhang
    Institute of Nephrology and Division of Nephrology, Peking University First Hospital, Beijing, PR China
    Am J Kidney Dis 51:373-84. 2008
    ..Chronic kidney disease (CKD) is considered a serious worldwide public health problem, but data from developing countries are extremely limited...
  46. pmc Immunocytology is a strong predictor of bladder cancer presence in patients with painless hematuria: a multicentre study
    Eugene K Cha
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA
    Eur Urol 61:185-92. 2012
    Although the performance of immunocytology has been established in the surveillance of patients with urothelial carcinoma of the bladder (UCB), its value in the initial detection of UCB in patients with painless hematuria remains unclear.
  47. pmc Balloon-occluded percutaneous transhepatic obliteration of isolated vesical varices causing gross hematuria
    Dong hoon Lim
    Department of Urology, College of Medicine, Chosun University, Gwangju 501 717, Korea
    Korean J Radiol 14:94-6. 2013
    Gross hematuria secondary to vesical varices is an unusual presentation...
  48. ncbi COL4A4 mutation in thin basement membrane disease previously described in Alport syndrome
    M Buzza
    University Department of Medicine, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Kidney Int 60:480-3. 2001
    ..we have shown that many individuals with thin basement membrane disease (TBMD) are also from families where hematuria segregates with the COL4A3/COL4A4 locus...
  49. ncbi Split-bolus MDCT urography: Upper tract opacification and performance for upper tract tumors in patients with hematuria
    Ekta Maheshwari
    Joint Department of Medical Imaging, University of Toronto, ON, Canada
    AJR Am J Roentgenol 194:453-8. 2010
    Our purpose was to assess upper urinary tract opacification and the performance of split-bolus MDCT urography for upper tract tumors in patients with hematuria.
  50. ncbi Persistent glomerular hematuria in living kidney donors confers a risk of progressive kidney disease in donors after heminephrectomy
    R Kido
    Department of Nephrology and Endocrinology, University of Tokyo, Japan
    Am J Transplant 10:1597-604. 2010
    Although glomerular hematuria is likely a sign of chronic kidney disease that will develop into overt nephropathy after donation, it remains unclear whether prospective donors with hematuria should be excluded...
  51. ncbi Abberant sex habits leading to acute limb ischemia and hematuria
    R J Toorop
    Department of Surgery, Maxima Medical Centre, Veldhoven, The Netherlands
    Eur J Vasc Endovasc Surg 33:340-2. 2007
    ..Upon urokinase treatment he developed gross hematuria. Finally, CT scanning revealed a self-inserted foreign body not only causing thrombosis of the external iliac ..
  52. ncbi Bladder cancer: diagnosis with diffusion-weighted MR imaging in patients with gross hematuria
    Mohamed E Abou-El-Ghar
    Departments of Radiology, and Urology, Urology and Nephrology Center, Mansoura University, Mansoura 35516, Egypt
    Radiology 251:415-21. 2009
    To prospectively evaluate the usefulness of diffusion-weighted (DW) magnetic resonance (MR) imaging for the detection of bladder neoplasms in patients with gross hematuria of lower urinary tract origin.
  53. ncbi Incarcerated vesicoinguinal hernia presenting with gross hematuria
    Sergio Huerta
    University of California, Irvine Medical Center, Orange, CA, USA
    J Am Coll Surg 201:992-3. 2005
  54. ncbi The presence of microscopic hematuria detected by urine dipstick test in the evaluation of patients with renal colic
    A Argyropoulos
    Urology Clinic, Athens General Hospital G Gennimatas, Athens, Greece
    Urol Res 32:294-7. 2004
    ..One of the most important steps in the diagnostic algorithm of renal colic is the presence of hematuria, but this fact has been challenged by authors reporting a negative urinalysis for microscopic hematuria in about ..
  55. ncbi Glomerulonephritis in Behçet's disease: report of seven cases and review of the literature
    M R Altiparmak
    Cerrahpasa Medical School, University of Istanbul, Turkey
    Clin Rheumatol 21:14-8. 2002
    ..According to our results, we can conclude that urinary abnormalities are more frequent in BD; however, serious renal lesions develop in only very few of these patients...
  56. ncbi AKI associated with macroscopic glomerular hematuria: clinical and pathophysiologic consequences
    Juan Antonio Moreno
    Division of Nephrology and Hypertension, IIS Fundación Jiménez Díaz, Autonoma University, Madrid, Spain
    Clin J Am Soc Nephrol 7:175-84. 2012
    b>Hematuria is a common finding in various glomerular diseases. This article reviews the clinical data on glomerular hematuria and kidney injury, as well as the pathophysiology of hematuria-associated renal damage...
  57. pmc The use of molecular analyses in voided urine for the assessment of patients with hematuria
    Willemien Beukers
    Department of Pathology, Erasmus MC, Rotterdam, The Netherlands
    PLoS ONE 8:e77657. 2013
    Patients presenting with painless hematuria form a large part of the urological patient population. In many cases, especially in younger patients, the cause of hematuria is harmless...
  58. ncbi Multidetector computerized tomography urography is more accurate than excretory urography for diagnosing transitional cell carcinoma of the upper urinary tract in adults with hematuria
    Li Jen Wang
    Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    J Urol 183:48-55. 2010
    ..We compared accuracy measures of both methods for diagnosing upper urinary tract transitional cell carcinoma in adult patients with hematuria.
  59. ncbi Immunocytology in the assessment of patients with asymptomatic microhaematuria
    Bernd J Schmitz-Drager
    Urologie, EuromedClinic, Fürth, Germany
    Eur Urol 51:1582-8; discussion 1588. 2007
    ..Discrimination between malignant and nonmalignant conditions remains the key problem in assessing microhaematuria. This prospective study investigated the role of immunocytology in the evaluation of patients with microhaematuria...
  60. ncbi Familial hematuria due to type IV collagen mutations: Alport syndrome and thin basement membrane nephropathy
    Clifford E Kashtan
    University of Minnesota Medical School, Department of Pediatrics, Minneapolis, Minnesota 55455, USA
    Curr Opin Pediatr 16:177-81. 2004
    ..that mutations in type IV collagen account for a significant proportion of patients with persistent glomerular hematuria. This review will discuss the implications of these findings for the diagnosis and management of persistent ..
  61. ncbi Spontaneous rupture of hypogastric artery aneurysm into the bladder: a case report and review of the literature
    Kambiz Jacob Cohen-Kashi
    Department of Surgery, North Shore Long Island Jewish Health System, Manhasset, NY, USA
    Ann Vasc Surg 20:134-7. 2006
    ..male with spontaneous rupture of a hypogastric artery aneurysm into the urinary bladder presenting as gross hematuria. This case illustrates the importance of a high index of suspicion in diagnosis and early treatment to reduce ..
  62. pmc The performance of haematuria reagent strips for the rapid mapping of urinary schistosomiasis: field experience from Southern Sudan
    Emily Robinson
    Malaria Consortium Africa Regional Office, Kampala, Uganda
    Trop Med Int Health 14:1484-7. 2009
    ..These findings suggest that reagent strips alone are not sufficient for rapid mapping surveys. A two-step approach is thus recommended whereby haematuria-positive urine samples are subsequently examined using urine filtration...
  63. ncbi Gross and microscopic hematuria: guidelines for obstetricians and gynecologists
    Katherine Shaio Sandhu
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology and Women s Health, Albert Einstein College of Medicine Montefiore Medical Center Bronx, New York, NY 10467, USA
    Obstet Gynecol Surv 64:39-49. 2009
    Although gross hematuria is a relatively uncommon condition in general obstetrics and gynecology practice, microscopic hematuria is a common incidental finding during routine antepartum or gynecologic office visits...
  64. ncbi Imaging of hematuria
    Owen J O'Connor
    Department of Radiology, University College Cork, Cork, Ireland
    AJR Am J Roentgenol 195:W263-7. 2010
    In this article, we will discuss the current status of imaging in patients with hematuria of urologic origin...
  65. ncbi Hematuria and dysuria in the self-diagnosis of urinary schistosomiasis among school-children in Northern Cameroon
    Innocent Takougang
    Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, B P 1364 Yaoundé, Cameroon
    Afr J Health Sci 11:121-7. 2004
    The present study was designed to assess the value of self reported hematuria and dysuria in the diagnosis of urinary schistosomiasis at the individual level...
  66. ncbi Imaging of hematuria
    Owen J O'Connor
    Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland
    Radiol Clin North Am 46:113-32, vii. 2008
    b>Hematuria may have a number of causes, of which the more common are urinary tract calculi, urinary tract infection, urinary tract neoplasms (including renal cell carcinoma and urothelial tumors), trauma to the urinary tract, and renal ..
  67. ncbi False-positive results of the NMP22 test due to hematuria
    Necmettin Atsu
    Department of Urology, Hacettepe University, Ankara, Turkey
    J Urol 167:555-8. 2002
    ..Cambridge, Massachusetts) are usually observed in some clinical categories that are usually associated with hematuria and pyuria. This problem is especially serious in bladder cancer since 85% of patients present with hematuria...
  68. ncbi Thin glomerular basement membrane nephropathy: incidence in 3471 consecutive renal biopsies examined by electron microscopy
    Mark Haas
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 130:699-706. 2006
    Thin glomerular basement membrane (GBM) nephropathy is often equated with benign familial hematuria, although it may occur sporadically and may not always be benign...
  69. ncbi Molecular analysis of the fragile histidine triad (FHIT) tumor suppressor gene in vesical tumors of cattle with chronic enzootic hematuria (CEH)
    E Guidi
    Department of Genetics and Microbiology A Buzzati Traverso, University of Pavia, Pavia, Italy
    Cytogenet Genome Res 120:173-7. 2008
    ..to test whether FHIT presents altered expression patterns in vesical tumors of cattle with CEH (chronic enzootic hematuria)...
  70. ncbi Pathologic quiz case: a 35-year-old man with hematuria. Paraganglioma involving the prostate
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Arch Pathol Lab Med 128:e104-6. 2004
  71. ncbi Utility of hematuria testing in patients with suspected renal colic: correlation with unenhanced helical CT results
    Jonathan S Luchs
    Department of Radiology, Winthrop University Hospital, Mineola, New York 11501, USA
    Urology 59:839-42. 2002
    To determine the utility of hematuria testing in a large series of patients with suspected renal colic using unenhanced helical computed tomography (CT) as the reference standard.
  72. ncbi An unusual cause of gross hematuria and transient ARF in an SLE patient with warfarin coagulopathy
    Anwarul Kabir
    Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210 1250, USA
    Am J Kidney Dis 43:757-60. 2004
  73. ncbi Gross hematuria in children: a ten-year review
    Saul P Greenfield
    Department of Pediatric Urology, Women and Children s Hospital of Buffalo, Buffalo, New York 14222, USA
    Urology 69:166-9. 2007
    Gross hematuria in children is uncommon. We reviewed our experience characterizing its clinical presentation and diagnosis.
  74. ncbi Consensus statement on evaluation of hematuria
    K D Phadke
    Childrens Kidney Care Center, Department of Pediatrics, St Johns Medical College Hospital, Sarjapur Road, Bangalore 560 034
    Indian Pediatr 43:965-73. 2006
  75. ncbi Hematuria as the presenting symptom of a metastatic thyroid cancer
    Pietro Pepe
    Urology, Unit of Cannizzaro Hospital, Catania, Italy
    Urol Int 76:89-90. 2006
    A 67-year-old man is presented who was admitted to our hospital for the onset of hematuria and acute urinary retention and who was found to have a 10-cm solid mass in the right obturator fossa compressing the bladder wall...
  76. ncbi Botryoid Wilms' tumor: a report of two cases
    Toshihiro Yanai
    Department of Pediatric Surgery, Juntendo University School of Medicine, 2 1 1 Hongo, 113 8421 Bunkyo ku, Tokyo, Japan
    Pediatr Surg Int 21:43-6. 2005
    ..No local recurrence or metastatic spread has been detected for 4 years postoperatively in case 1 and for 9 months postoperatively in case 2...
  77. ncbi A family with X-linked benign familial hematuria
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 25:545-8. 2010
    ..and COL4A4 located on chromosome 2 are associated with autosomal inherited Alport syndrome or benign familial hematuria. A family with benign familial hematuria caused by COL4A5 mutation, implying X-linked transmission, is reported ..
  78. ncbi Ureteroscopic evaluation and laser treatment of chronic unilateral hematuria
    Soichi Mugiya
    Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan
    J Urol 178:517-20. 2007
    Chronic unilateral hematuria is characterized by intermittent or continuous gross hematuria that cannot be diagnosed using standard radiology and hematology methods...
  79. ncbi Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases
    Kesha Rana
    Department of Medicine AH NH, The Northern Hospital, University of Melbourne, Epping, Vic, 3076, Australia
    Pediatr Nephrol 22:652-7. 2007
    ..The identification of polymorphisms in these genes is particularly important to enable diagnostic laboratories to distinguish mutations from uncommon normal variants...
  80. doi Hematuria: definition and screening test methods
    Eiji Higashihara
    The Japanese Urological Association, Tokyo, Japan
    Int J Urol 15:281-4. 2008
  81. ncbi Isolated hemangioma causing gross painless hematuria in an adolescent male
    Jeremy B Wiygul
    Schneider Children s Hospital, New Hyde Park, New York, New York, USA
    Urology 76:463-4. 2010
    b>Hematuria in children is usually a benign entity, with hypercalciuria being the usual etiology; however, rarer causes also exist, including genitourinary hemangioma...
  82. ncbi Gross hematuria in a 3-year-old girl caused by a large isolated bladder hemangioma
    Richard A Ashley
    Department of Urology, Nemours A I duPont Hospital for Children, Wilmington, Delaware, USA
    Urology 76:952-4. 2010
    ..Although rare, these lesions can result in significant hematuria, with potential for patient morbidity...
  83. ncbi Evaluation of hematuria in children
    Kevin E C Meyers
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Main Building, 2nd Floor, Philadelphia, PA 19104 4399, USA
    Urol Clin North Am 31:559-73, x. 2004
    The detection of blood in a child's urine is alarming and often prompts many laboratory studies. Hematuria is one of the most important signs of renal or bladder disease, but proteinuria often is a more important diagnostic and ..
  84. ncbi Management of chronic unilateral hematuria by ureterorenoscopy
    Artur Henrique Brito
    Division of Urology, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Endourol 23:1273-6. 2009
    Chronic unilateral hematuria is characterized by intermittent or continuous gross hematuria that cannot be diagnosed using standard radiology and hematology methods. In the past, it was managed with partial or total nephrectomy...
  85. ncbi Correlation between mRNA expression level of the mutant COL4A5 gene and phenotypes of XLAS females
    Yunfeng Wang
    Department of Pediatrics, Peking University First Hospital, Beijing, PR China
    Exp Biol Med (Maywood) 232:638-42. 2007
    Alport syndrome (AS) is a progressive hereditary glomerulonephritis presented with hematuria, progressive renal failure, sensorineural deafness, and ocular lesions...
  86. ncbi Benign familial hematuria associated with a novel COL4A4 mutation
    S Ozen
    Department of Pediatric Nephrology and Rheumatology, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey
    Pediatr Nephrol 16:874-7. 2001
    We describe a father and three offspring with hematuria. The father and one girl also complained of flank pain. Renal function tests and ophthalmological examinations were normal in all. The father had very mild neural deafness...
  87. ncbi Bladder varices--rare cause of painless hematuria in idiopathic retroperitoneal fibrosis
    C George Koshy
    Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
    Urology 73:58-9. 2009
    A patient presented to the urology outpatient department with complaints of recurrent episodes of painless hematuria. A contrast-enhanced computed tomography scan of the abdomen revealed vesical varices that had developed secondary to ..
  88. ncbi Sickle cell trait and gross hematuria
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, New York, New York, USA
    Kidney Int 71:706-10. 2007
  89. ncbi Impact of date of onset on the absence of hematuria in patients with acute renal colic
    Takashi Kobayashi
    Department of Urology, Hamamatsu Rosai Hospital, Japan
    J Urol 170:1093-6. 2003
    b>Hematuria is absent in a significant proportion of patients with acute ureterolithiasis. We determined whether time from pain onset has any impact on the sensitivity of hematuria tests in the diagnosis of ureterolithiasis.
  90. ncbi Evaluation of hematuria and proteinuria: how should a pediatrician proceed?
    Raymond Quigley
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Curr Opin Pediatr 20:140-4. 2008
    ..The review will discuss the major causes of hematuria and proteinuria in the pediatric population, and discuss a rational approach to the evaluation of these ..
  91. ncbi Forget the blood, not the stone! Microhaematuria in acute urolithiasis and the role of early CT scanning
    K Xafis
    Department of Emergency Medicine, University Hospital of Berne, Berne 3010, Switzerland
    Emerg Med J 25:640-4. 2008
    ..Although urinalysis is simple and inexpensive to perform, the finding of microhaematuria on urinalysis may be unreliable for diagnosing urolithiasis...
  92. ncbi When is red urine not hematuria?: A case report
    Jason S Bryant
    Department of Emergency Medicine, Kaiser Permanente Medical Center, Santa Clara, California 95051, USA
    J Emerg Med 32:55-7. 2007
    The definition of gross hematuria is "the presence of blood in the urine in sufficient quantity to be visible to the naked eye...
  93. ncbi Prevalence and risk factors of chronic kidney disease in first-degree relatives of chronic kidney disease patients in Southern China
    Xin Wei
    Department of Nephrology Epidemiology and Clinical Research Unit, The First Affiliated Hospital Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat Sen University, Guangzhou, China
    Nephrology (Carlton) 17:123-30. 2012
    ..The aim of this study was to estimate the prevalence and risk factors of chronic kidney disease (CKD) in first-degree relatives (FDRs) of CKD patients...
  94. ncbi Absent hematuria and expensive computerized tomography: case characteristics of emergency urolithiasis
    J Li
    Division of Emergency Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, Massachusetts, USA
    J Urol 165:782-4. 2001
    ..RESULTS: From 159,083 emergency visits during this period 397 met study entry criteria. Absent hematuria was noted in 9% (95% confidence interval 7% to 12%) of patients with proved urolithiasis...
  95. ncbi Blunt traumatic hematuria in children. Is a simplified algorithm justified?
    Marcos R Perez-Brayfield
    Division of Pediatric Urology, Department of Urology, Emory University School of Medicine, Atlanta, GA, USA
    J Urol 167:2543-6; discussion 2546-7. 2002
    We determined whether radiographic evaluation is indicated in all children with traumatic hematuria.
  96. ncbi Multidetector computerized tomography urography as the primary imaging modality for detecting urinary tract neoplasms in patients with asymptomatic hematuria
    Gary S Sudakoff
    Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Urol 179:862-7; discussion 867. 2008
    We determined whether multidetector computerized tomography urography is sensitive and specific for detecting urinary tract neoplasms when used as the primary imaging modality for evaluating patients with hematuria.
  97. ncbi [Experience in superselective embolization of bladder arteries in the treatment of intractable hematuria]
    C Palma Ceppi
    Servicio de Urologia, Hospital Clinico, Universidad de Chile
    Actas Urol Esp 32:542-5. 2008
    The hematuria, one of the main motives of urologic consultations, is produced by an extensive number of urinary pathologies from infections to cancer...
  98. ncbi Evaluation of gross hematuria
    Cynthia G Pan
    Division of Pediatric Nephrology, Medical College of Wisconsin and Children s Hospital of Wisconsin, Suite 510, Children s Corporate Center, PO Box 1997, Milwaukee, WI 53201 1997, USA
    Pediatr Clin North Am 53:401-12, vi. 2006
    Gross hematuria in children is a common complaint that often leads patients to seek urgent care. The diagnostic evaluation can be chosen based on specific patient history and physical examination...
  99. ncbi Patterns of hematuria referral to urologists: does a gender disparity exist?
    Emilie K Johnson
    Department of Urology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Urology 72:498-502; discussion 502-3. 2008
    To examine the referral patterns of hematuria within a nonprofit healthcare organization to determine the factors that influence referral. Hematuria continues to be an important sign of urologic disease, including urothelial malignancy...
  100. ncbi Traumatic hematuria in children can be evaluated as in adults
    Richard A Santucci
    Department of Urology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Urol 171:822-5. 2004
    ..Adult blunt trauma victims who present without gross hematuria, shock, or significant deceleration or other major associated injuries do not require renal imaging...
  101. ncbi Renal cell carcinoma presenting as Henoch-Schönlein purpura with leukocytoclastic vasculitis, hematuria, proteinuria and abdominal pain
    Young Hoon Hong
    Division of Rheumatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea
    Rheumatol Int 30:1373-6. 2010
    ..Here, we report a case of LCV associated with RCC presenting as HSP. This case illustrates the importance of evaluating patients for an underlying malignancy when HSP or LCV is diagnosed...

Research Grants49

  1. Optically-Guided Bladder Biopsy Using Polarized Elastic Scattering Spectroscopy
    FREDERICK GEORGE BARGOOT; Fiscal Year: 2010
    ..This is generally performed when a patient presents with symptoms like hematuria or abnormal cells in the urine. This is followed by biopsy and surgical intervention...
  2. Multi-center Controlled Clinical Trials in Alport Syndrome-A Feasibility Study
    Clifford E Kashtan; Fiscal Year: 2013
    ..the past 30 years much has been learned about the molecular genetics and natural history of familial forms of hematuria. However, enhanced understanding of these conditions has yet to generate effective therapies for Alport syndrome,..
  3. Ameliorating Sickle Nephropathy and Pulmonary Hypertension
    Punam Malik; Fiscal Year: 2013
    ..Also seen is hematuria (gross or microscopic) from medullary tubulo-interstitial damage...
  4. Computer-Aided Detection of Urinary Tract Cancer on MDCT Urography
    LUBOMIR M HADJIYSKI; Fiscal Year: 2013
    ..imaging modality for early detection of bladder and upper urinary tract cancer, which can be a cause of hematuria. The prevalence of hematuria can be as high as 19% in elderly patients...
  5. The Quality of Care in Evaluating Patients Suspected of Having Bladder Cancer
    Daniel A Barocas; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The presence of blood in the urine, or "hematuria", may herald the presence of urologic malignancy such as bladder cancer or kidney cancer;benign urologic disease such as kidney stones (..
  6. Aurora Kinase A as a Biomarker for the Detection of Bladder Cancer
    Bogdan A Czerniak; Fiscal Year: 2013
    ..Specific Aim 2: Validate a model for BC detection in patients with hematuria and determine if Aurora A FISH and/or UroVysion FISH improves the model...
  7. HIV ASSOCIATED NEPHROPATHY IN CHILDREN
    JOSE STRAUSS; Fiscal Year: 1993
    ..Those patients with persistent abnormal proteinuria or hematuria, increased kidney size or echogenicity, or decreased GFR will have a Gallium scan and a renal biopsy...
  8. CHLOROANILINE-INDUCED NEPHROTOXICITY
    GARY RANKIN; Fiscal Year: 1992
    ..of toxicities which include hematotoxicity (methemoglobinemia, hemolytic anemia), nephrotoxicity (oliguria, hematuria, tubular necrosis) and to a lesser extent, hepatotoxicity...
  9. MEDICAL THERAPY OF PROSTATIC SYMPTONS (MTOPS)
    Kevin McVary; Fiscal Year: 2001
    ..to BPH can result in renal failure, disruptive bladder symptoms, urinary retention, UTI, bladder stones and hematuria. Current studies estimate 30% of American males will require a surgical procedure to correct this problem ..
  10. Laminin Alpha5 and Polycystic Kidney Disease
    JEFFREY MINER; Fiscal Year: 2007
    ..Preliminary studies show that LamaSneo/neo mice die at ~23 days of age with multiple large cysts, proteinuria, hematuria, and reduced levels of laminin a5 in most kidney basement membranes...
  11. Urine Crystal Inhibition in Pediatric Nephrolithiasis
    KRISTIN BERGSLAND; Fiscal Year: 2007
    ..clinical assays that can predict the development of stones in children with nephrolithiasis and the syndrome of hematuria due to hypercalciuria...
  12. LCAT SUBSTRATE SPECIFICITY IN FISH EYE DISEASE
    Katherine Miller; Fiscal Year: 1999
    ..Symptoms of FLD include nephropathy, renal insufficiency, proteinuria, hematuria, anemia and cloudy corneas...
  13. PROTEIN-CARBOHYDRATE INTERACTION
    Irwin Goldstein; Fiscal Year: 2007
    ..of the Marasmius oreades mushroom lectin which binds specifically to murine renal glomeruli causing protein-and hematuria as a model for human kidney disease; possible aberrant glycosylation of human serum glycoproteins by recombinant ..
  14. Mouse Model of X-Linked Alport Syndrome
    Yoav Segal; Fiscal Year: 2003
    ..As X-linked Alport syndrome is an archetypal basement membrane disorder, producing hematuria as a primary manifestation, we plan to build on existing knowledge of the glomerular capillary wall, to ..
  15. Cardiac and Renal Disease Study (CARDS)
    Carlos Iribarren; Fiscal Year: 2003
    ..of the subsequent risk of ESRD after adjusting for diabetes and for baseline serum creatinine, proteinuria and hematuria. Aim 3: To examine other potential predictors of ESRD including demographic factors (race/ethnicity, level of ..
  16. GLOMERULAR PERMSELECTIVITY IN ALPORT SYNDROME
    Clifford Kashtan; Fiscal Year: 2004
    ..This trial will compare urinary protein levels, kidney function, and renal structural changes in treated and untreated dogs. ..
  17. Clinical Decision Rule to Identify Children with Intra-Abdominal Injuries
    James Holmes; Fiscal Year: 2008
    ..unreadable]..
  18. Patient-Oriented Models for Urinary Function in Women
    Linda Brubaker; Fiscal Year: 2008
    ..unreadable] b. To model urinary storage in health and disease [unreadable] c. To model urinary emptying in health and diseas [unreadable] [unreadable]..
  19. Thyroid Stimulating Hormone Promotes the Growth and Progression of Human Melanoma
    Julie Ellerhorst; Fiscal Year: 2008
    ..Furthermore, melanoma cases may be prevented by heightened surveillance of individuals with a history of hypothyroidism. [unreadable] [unreadable] [unreadable]..
  20. Symposium for Molecular and Therapeutic Insights in PKD
    Arlene Chapman; Fiscal Year: 2002
    ..Day 5 will be devoted to autosomal recessive kidney diseases and the last half day will be devoted to potential therapeutic strategies in cystic disorders of the kidney. ..
  21. The Coronary Screening for Kidney Transplantation (COST) Study
    Bertram Kasiske; Fiscal Year: 2008
    ..The money spent on these procedures might be better directed to health care measures of proven efficacy. [unreadable] [unreadable] [unreadable]..
  22. BIOEFFECTS OF GAS BODY ACTIVATION IN MEDICAL ULTRASOUND
    Douglas Miller; Fiscal Year: 2009
    ..This project will examine bioeffects in cells and tissues and show how to safely use ultrasound contrast agents in diagnostic imaging. ..
  23. Pyrophosphate in vascular calcification of renal failure
    W CHARLES O apos NEILL; Fiscal Year: 2010
    ..The results will establish a new paradigm for vascular calcification in renal failure and form the basis for important clinical trials in humans. ..
  24. COAGULATION ACTIVATION IN SICKLE CELL DISEASE
    Kenneth I Ataga; Fiscal Year: 2010
    ..abstract_text> ..
  25. MR Imaging of Non-Alcoholic Fatty Liver Disease
    Claude B Sirlin; Fiscal Year: 2010
    ..Developing a safe and accurate method to diagnose and follow this disease may lead to earlier diagnosis and more effective treatment. ..
  26. Consequences of Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2006
    ..These will contribute greatly to my development into an independent investigator. ..
  27. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2010
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  28. COMPLEMENT AND B CELL TOLERANCE IN A MURINE MODEL OF SLE
    Elahna Paul; Fiscal Year: 2002
    ..By combining immunologic, nephrologic and molecular analyses I propose to elucidate how classical complement deficiency predisposes to SLE. ..
  29. MOLECULAR REGULATION OF ENDOTHELIAL NA K 2CL COTRANSPORT
    W O NEILL; Fiscal Year: 2002
    ..abstract_text> ..
  30. ULTRASOUND ENHANCEMENT OF CANCER GENE THERAPY
    Douglas Miller; Fiscal Year: 2002
    ..This research will provide a bridge from the basic research breakthrough to specific therapeutic applications and urgently needed clinical research programs utilizing this novel technology. ..
  31. BIOEFFECTS OF GAS BODY ACTIVATION IN MEDICAL ULTRASOUND
    Douglas Miller; Fiscal Year: 2001
    ..abstract_text> ..
  32. Heparin-Binding EGF in Autosomal Recessive PKD
    Katherine Dell; Fiscal Year: 2007
    ..These studies will provide important insights into ARPKD disease pathogenesis and may identify potential new therapeutic targets. ..
  33. Effect of Pyridoxamine in Oxalate excretion in Stone Disease and Hyperoxaluria
    Jon Scheinman; Fiscal Year: 2007
    ..The public health implications of this study are in its contributions to preventing common kidney stone disease, and preventing kidney failure in an orphan disease, Primary Hyperoxaluria. [unreadable] [unreadable] [unreadable]..
  34. Chronic Kidney Disease with Benign Prostatic Hyperplasia
    ANDREW RULE; Fiscal Year: 2004
    ..Based on preliminary data, a significant association between BPH surrogate measures and CKD is expected. This study will clarify whether earlier assessment and intervention in BPH is warranted to prevent CKD. ..
  35. Renal Volume Measurement to Detect Early Kidney Disease
    W O NEILL; Fiscal Year: 2004
    ..abstract_text> ..
  36. Live Unrelated Kidney Donor & Sibling Follow-up Study
    Bertram Kasiske; Fiscal Year: 2005
    ..Altogether, this study will provide useful information that will improve the informed consent for living kidney donors and enhance our knowledge of the role of the kidney, if any, in CVD. ..
  37. Genetic and molecular characterization of kidney cancer
    Allan Pantuck; Fiscal Year: 2005
    ..abstract_text> ..
  38. Autoimmune Mechanisms in the Response to Renal Cancer
    Julie Ellerhorst; Fiscal Year: 2006
    ..These data will be clinically useful in predicting outcomes of RCC patients, as well as in the understanding of basic mechanisms of host-derived tumor control. ..
  39. TRH Production and Regulation by Human Melanoma
    Julie Ellerhorst; Fiscal Year: 2006
    ..In Specific Aim #2, cell lines will be used for in vitro studies to determine if one or more of the mechanisms of hypothalamic TRH regulation are relevant to the control of TRH production by melanoma cells. [unreadable] [unreadable]..
  40. DISORDERED BLOOD COAGULATION IN SICKLE CELL DISEASE
    Kenneth Ataga; Fiscal Year: 2006
    ..e., is the "hypercoagulability" observed in patients with SCD a primary cause of the vasoocclusion or is it simply a secondary event that is observed in this clinical setting. ..
  41. The Acquisition of Bacterial Vaginosis in Lesbians
    Jeanne Marrazzo; Fiscal Year: 2006
    ..Lesbian couples provide a unique opportunity to conduct comparative studies of vaginal microbial ecology in sex partners, and to directly analyze determinants of transmission. ..
  42. HUMAN POPULATION GROWTH IMPACT ON S. HAEMATOBIUM
    Charles King; Fiscal Year: 2005
    ....
  43. INSULIN RECEPTOR RELATED AND THE KIDNEY
    Carlton Bates; Fiscal Year: 2002
    ..After being subjected to systemic alkalosis, IRR-null mouse kidneys will be examined to determine if the intercalated cells have appropriately altered their morphology and intracellular distribution of proton transporters. ..
  44. ULTRASOUND ENHANCEMENT OF CANCER GENE THERAPY
    Douglas Miller; Fiscal Year: 2003
    ..This research will provide a bridge from the basic research breakthrough to specific therapeutic applications and urgently needed clinical research programs utilizing this novel technology. ..
  45. Linking acute, chronic and end-stage renal disease
    Chi yuan Hsu; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  46. URINARY SCHISTOSOMIASIS: INFECTION AND DISEASE
    Charles King; Fiscal Year: 2004
    ..This information, combined with epidemiological modeling of control strategies, will allow accelerated synthesis of the next generation of control programs. ..
  47. Transducible Molecular Probes for Imaging Tumors
    Claude Sirlin; Fiscal Year: 2004
    ..abstract_text> ..
  48. The Role of TGF-alpha in the Pathogenesis of ARPKD
    Katherine Dell; Fiscal Year: 2005
    ..Although the proposed research focuses on ARPKD, insights provided by these studies may contribute to a broader understanding of autosomal dominant polycystic kidney disease (ADPKD) as well. ..