vesico ureteral reflux

Summary

Summary: The passage of urine from the bladder back into a ureter. (Dorland, 27th ed)

Top Publications

  1. ncbi Epidemiology of chronic renal failure in children: data from the ItalKid project
    Gianluigi Ardissino
    Unit of Pediatric Nephrology, Dialysis and Transplantation, Department of Pediatrics, Milano, Italy
    Pediatrics 111:e382-7. 2003
  2. ncbi Endoscopic therapy for vesicoureteral reflux: a meta-analysis. I. Reflux resolution and urinary tract infection
    Jack S Elder
    Division of Pediatric Urology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    J Urol 175:716-22. 2006
  3. ncbi Prediction of vesico-ureteric reflux in childhood urinary tract infection: a multivariate approach
    R Oostenbrink
    Department of Paediatrics, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Paediatr 89:806-10. 2000
  4. ncbi Vesicoureteral reflux: can the urethra be adequately assessed by using contrast-enhanced voiding US of the bladder?
    Teresa Berrocal
    Department of Pediatric Radiology, University Hospital La Paz, Paseo de la Castellana 246, 28046 Madrid, Spain
    Radiology 234:235-41. 2005
  5. ncbi Contrast ultrasound of the urethra in children
    Alejandro Maté
    Department of Radiology, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 A Coruna, Spain
    Eur Radiol 13:1534-7. 2003
  6. ncbi Subureteral dextranomer/hyaluronic acid injection as first line treatment in the management of high grade vesicoureteral reflux
    Prem Puri
    National Children s Hospital, and Children s Research Centre, Our Lady s Hospital for Sick Children, University College Dublin, Crumlin, Dublin 2, Ireland
    J Urol 176:1856-9; discussion 1859-60. 2006
  7. ncbi Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux
    P Sanyanusin
    Department of Biochemistry, University of Otago, Dunedin, New Zealand
    Nat Genet 9:358-64. 1995
  8. ncbi Surgical management of vesicoureteral reflux in pediatric patients
    Axel Heidenreich
    Department of Urology, University of Koln, 50931 Cologne, Germany
    World J Urol 22:96-106. 2004
  9. ncbi Detection of posterior urethral valves with voiding cystourethrosonography with echo contrast
    M Bosio
    Section of Pediatric Nephrology, Department of Pediatrics and Advanced School of Pediatric Echocardiography, Ospedale di Magenta, Italy
    J Urol 168:1711-5; discussion 1715. 2002
  10. ncbi Screening siblings for vesicoureteral reflux
    Jean G Hollowell
    Department of Surgery Urology, Pinnacle Health Hospitals, Camp Hill, Pennsylvania, USA
    J Urol 168:2138-41. 2002

Detail Information

Publications265 found, 100 shown here

  1. ncbi Epidemiology of chronic renal failure in children: data from the ItalKid project
    Gianluigi Ardissino
    Unit of Pediatric Nephrology, Dialysis and Transplantation, Department of Pediatrics, Milano, Italy
    Pediatrics 111:e382-7. 2003
    ..This article reports the epidemiologic results...
  2. ncbi Endoscopic therapy for vesicoureteral reflux: a meta-analysis. I. Reflux resolution and urinary tract infection
    Jack S Elder
    Division of Pediatric Urology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    J Urol 175:716-22. 2006
    ..We performed a meta-analysis of the existing literature pertaining to endoscopic treatment to allow comparison with reports of open surgical correction...
  3. ncbi Prediction of vesico-ureteric reflux in childhood urinary tract infection: a multivariate approach
    R Oostenbrink
    Department of Paediatrics, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Paediatr 89:806-10. 2000
    ..69-0.87). This prediction model identified 12% (95% CI: 7-18) of the patients without VUR without missing one case of VUR. If we used VUR > or = grade 3 as a threshold, the model assessed VUR to be absent in 34% (95% CI: 26-42)...
  4. ncbi Vesicoureteral reflux: can the urethra be adequately assessed by using contrast-enhanced voiding US of the bladder?
    Teresa Berrocal
    Department of Pediatric Radiology, University Hospital La Paz, Paseo de la Castellana 246, 28046 Madrid, Spain
    Radiology 234:235-41. 2005
    ..To prospectively evaluate contrast material-enhanced voiding ultrasonography (US) for assessment of the urethra by using voiding cystourethrography (VCUG) as the reference standard...
  5. ncbi Contrast ultrasound of the urethra in children
    Alejandro Maté
    Department of Radiology, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 A Coruna, Spain
    Eur Radiol 13:1534-7. 2003
    ..Eighteen cases (5.14%) were excluded from the study because the quality of the examination was suboptimal. Transperineal US offers an initial imaging modality for studying urethral pathology and thus may complement VUS...
  6. ncbi Subureteral dextranomer/hyaluronic acid injection as first line treatment in the management of high grade vesicoureteral reflux
    Prem Puri
    National Children s Hospital, and Children s Research Centre, Our Lady s Hospital for Sick Children, University College Dublin, Crumlin, Dublin 2, Ireland
    J Urol 176:1856-9; discussion 1859-60. 2006
    ..We prospectively evaluated the effectiveness of dextranomer/hyaluronic acid copolymer (Deflux) as first line treatment for high grade vesicoureteral reflux...
  7. ncbi Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux
    P Sanyanusin
    Department of Biochemistry, University of Otago, Dunedin, New Zealand
    Nat Genet 9:358-64. 1995
    ..The phenotype resulting from the PAX2 mutation in this family was very similar to abnormalities that have been reported in Krd mutant mice. These data suggest that PAX2 is required for normal kidney and eye development...
  8. ncbi Surgical management of vesicoureteral reflux in pediatric patients
    Axel Heidenreich
    Department of Urology, University of Koln, 50931 Cologne, Germany
    World J Urol 22:96-106. 2004
    ..Therefore, the indication for surgery and the surgical technique applied have to be discussed thoroughly and must be associated with a minimal complication rate...
  9. ncbi Detection of posterior urethral valves with voiding cystourethrosonography with echo contrast
    M Bosio
    Section of Pediatric Nephrology, Department of Pediatrics and Advanced School of Pediatric Echocardiography, Ospedale di Magenta, Italy
    J Urol 168:1711-5; discussion 1715. 2002
    ..We determined whether cystosonography during the voiding phase (voiding cystourethrosonography) can adequately visualize the male urethra and differentiate the normal from the obstructed urethra...
  10. ncbi Screening siblings for vesicoureteral reflux
    Jean G Hollowell
    Department of Surgery Urology, Pinnacle Health Hospitals, Camp Hill, Pennsylvania, USA
    J Urol 168:2138-41. 2002
    ..Publications on screening the siblings of patients with reflux were reviewed to determine the overall incidence and severity of reflux and renal scarring in siblings, and identify factors that predict siblings more likely to have reflux...
  11. ncbi Cessation of prophylactic antibiotics for managing persistent vesicoureteral reflux
    R H Thompson
    School of Public Health, St. Louis University, St. Louis, Missouri, USA
    J Urol 166:1465-9. 2001
    ..2% of all boys and 4% of all girls. CONCLUSIONS: Our findings imply that discontinuing antibiotics is reasonable and safe in patients in whom vesicoureteral reflux fails to resolve...
  12. ncbi Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity
    Songshan Jiang
    Epithelial Biology Unit, Ronald O Perelman Department of Dermatology, Kaplan Comprehensive Cancer Center, New York University Medical School, New York, New York, USA
    Kidney Int 66:10-9. 2004
    ..Recent studies indicate that genetic ablation of mouse uroplakin (UP) III gene, which encodes a 47 kD urothelial-specific integral membrane protein forming urothelial plaques, causes VUR and hydronephrosis...
  13. ncbi The evolution of vesicoureteral reflux management in the era of dextranomer/hyaluronic acid copolymer: a pediatric health information system database study
    Thomas S Lendvay
    Division of Pediatric Urology and Department of Pediatric Medicine, University of Washington Children s Hospital and Regional Medical Center, 4800 Sand Point Way Northeast, Seattle, WA 98105, USA
    J Urol 176:1864-7. 2006
    ..We used the Pediatric Health Information System database to define practice trends for vesicoureteral reflux therapy...
  14. ncbi A multivariate analysis of dysfunctional elimination syndrome, and its relationships with gender, urinary tract infection and vesicoureteral reflux in children
    John J Chen
    Department of Preventive Medicine, Stony Brook University, NY 11794 8036, USA
    J Urol 171:1907-10. 2004
    ..We explored and quantified the relationships between dysfunctional elimination syndrome (DES), and gender, urinary tract infection (UTI) and vesicoureteral reflux (VUR) in children...
  15. ncbi Familial vesicoureteral reflux
    Boris Chertin
    Children s Research Centre, Our Lady s Hospital for Sick Children, University College Dublin, Dublin, Ireland
    J Urol 169:1804-8. 2003
    ..Vesicoureteral reflux is known to occur in families. We summarized worldwide data on the incidence and nature of vesicoureteral reflux in siblings of children with vesicoureteral reflux...
  16. ncbi Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis
    Isky Gordon
    Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London
    J Am Soc Nephrol 14:739-44. 2003
    ..Furthermore, the pathogenesis of renal damage in such patients is probably complex because it is often detected without demonstrable VUR...
  17. pmc Renal ultrasound findings and vesicoureteral reflux in children hospitalised with urinary tract infection
    S Mahant
    Paediatric Outcomes Research Team PORT, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada
    Arch Dis Child 86:419-20. 2002
    ..To determine the sensitivity, specificity, and predictive values of renal ultrasound findings for vesicoureteral reflux (VUR)...
  18. ncbi Prophylactic antibiotics in children at risk for urinary tract infection
    Stanley Hellerstein
    Section of Nephrology, The Children s Mercy Hospital, The University of Missouri School of Medicine at Kansas City, 2401 Gillham Road, MO 64108, USA
    Pediatr Nephrol 17:506-10. 2002
    ..Lesser grades of VUR and constipation did not significantly increase the risk of UTI. These observations should be useful in developing a study to define the risks and benefits of prophylactic antibiotic in "at-risk" children...
  19. ncbi Vesicoureteric reflux and renal malformations: a developmental problem
    I J Murawski
    Department of Pediatrics and Human Genetics, Montreal Children s Hospital, McGill University, Montreal, Quebec, Canada
    Clin Genet 69:105-17. 2006
    ..Therefore, in these cases, the association of VUR and renal failure may be caused by a genetic defect affecting the formation of the kidney and the urinary tract...
  20. ncbi Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study
    Eduardo H Garin
    Department of Pediatrics, University of South Florida, Tampa, Florida, USA
    Pediatrics 117:626-32. 2006
    ....
  21. ncbi Imaging studies after a first febrile urinary tract infection in young children
    Alejandro Hoberman
    Department of Pediatrics, University of Pittsburgh School of Medicine and Children s Hospital of Pittsburgh, Pittsburgh 15213 2583, USA
    N Engl J Med 348:195-202. 2003
    ..We investigated whether imaging studies altered management or improved outcomes in young children with a first febrile urinary tract infection...
  22. ncbi Medical versus surgical treatment in children with severe bilateral vesicoureteric reflux and bilateral nephropathy: a randomised trial
    J M Smellie
    Great Ormond Street Hospital for Children NHS Trust and Institute of Child Health, University College London, WC1N 1EH, London, UK
    Lancet 357:1329-33. 2001
    ..1%, 95% CI 6.4% to 20.6%). INTERPRETATION: Our data do not lend support to the view that the outcome for renal function is improved by surgical correction of VUR in children with bilateral disease...
  23. ncbi Reduction in voiding cystourethrographies after the introduction of contrast enhanced sonographic reflux diagnosis
    K Darge
    Department of Paediatric Radiology, Radiological Clinic, Heidelberg University Hospital, Im Neuenheimer Feld 153, 69 120 Heidelberg, Germany
    Pediatr Radiol 31:790-5. 2001
    ....
  24. ncbi Medical management of vesicoureteral reflux--quiz within the article. Don't overlook placebos
    Tej K Mattoo
    Division of Pediatric Nephrology, Children s Hospital of Michigan, Detroit, MI, USA
    Pediatr Nephrol 22:1113-20. 2007
    ..However, until proven otherwise by a prospective, placebo-controlled, randomized study, it is advisable to err on the side of caution and consider VUR and UTI risk factors for renal scarring and treat each patient on individual basis...
  25. ncbi Vesicoureteral reflux and clinical outcomes in infants with prenatally detected hydronephrosis
    M Michele Brophy
    Division of Pediatric Urology, St Louis Children s Hospital and Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 168:1716-9; discussion 1719. 2002
    ..We evaluate the incidence of vesicoureteral reflux and urinary tract infections in infants with prenatally detected hydronephrosis...
  26. ncbi Procalcitonin as a predictor of vesicoureteral reflux in children with a first febrile urinary tract infection
    Sandrine Leroy
    Department of Pediatrics, Saint Vincent de Paul Hospital, AP HP, Universite Paris V, Paris, France
    Pediatrics 115:e706-9. 2005
    ..Because procalcitonin has been shown to be associated with severe pyelonephritis and renal scars, which are correlated to vesicoureteral reflux, we analyzed its relationship with vesicoureteral reflux...
  27. ncbi Vesicoureteral reflux: diagnosis and grading with echo-enhanced cystosonography versus voiding cystourethrography
    T Berrocal
    Department of Pediatric Radiology, University Hospital La Paz, Paseo de la Castellana 261, 28046 Madrid, Spain
    Radiology 221:359-65. 2001
    ..To evaluate the usefulness of echo-enhanced cystosonography compared with voiding cystourethrography (VCUG) for detecting and grading vesicoureteral reflux (VUR)...
  28. ncbi Embryology and genetics of primary vesico-ureteric reflux and associated renal dysplasia
    Luisa Murer
    Paediatric Nephrology, Dialysis and Transplant Unit, Department of Paediatrics, University of Padova, Padova, Italy
    Pediatr Nephrol 22:788-97. 2007
    ..The present teaching paper is an overview of the embryology and genetics of primary VUR and associated congenital reflux nephropathy...
  29. ncbi Vesicoureteral reflux grading in contrast-enhanced voiding urosonography
    Kassa Darge
    Department of Pediatric Radiology, Institute of Radiodiagnostic, University Children s Hospital, Josef Schneiderstrasse 27 B34, 97080, Wuerzburg, Germany
    Eur J Radiol 43:122-8. 2002
    ..Furthermore, a reflux grading system for VUS is proposed and the correlation of this grading system tested with the one of VCUG...
  30. ncbi Salvage extravesical ureteral reimplantation after failed endoscopic surgery for vesicoureteral reflux
    James M Elmore
    Department of Pediatric Urology, Children s Healthcare of Atlanta and Emory University School of Medicine, 5445 Meridian Mark Road, Atlanta, GA 30342, USA
    J Urol 176:1158-60. 2006
    ..We reviewed our experience with extravesical ureteral reimplantation after dextranomer/hyaluronic acid failure...
  31. ncbi Primary ureteral reflux: emerging insights from molecular and genetic studies
    Robert H Mak
    Division of Pediatric Nephrology, Department of Pediatrics, Oregon Health and Science University, Mailcode NRC5, Portland, OR 97201, USA
    Curr Opin Pediatr 15:181-5. 2003
    ..Preliminary studies showed unique fingerprints in urinary protein patterns in children with primary VUR, providing the basis for developing novel noninvasive molecular diagnostic tests of vesicoureteral reflux by proteomics methodology...
  32. ncbi Protective effects of cranberries on infection-induced oxidative renal damage in a rabbit model of vesico-ureteric reflux
    Chang Hee Han
    Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea
    BJU Int 100:1172-5. 2007
    ..To evaluate the protective effects of cranberry fruit, which have known antioxidant effects, on infection-induced oxidative renal damage in a rabbit model of vesico-ureteric reflux (VUR)...
  33. ncbi Simultaneous voiding cystourethrography and voiding urosonography: an in vitro and in vivo study
    M Nakamura
    Department of Clinical Laboratory Medicine, Jichi Medical School, Minamikawachi, Tochigi, Japan
    Clin Radiol 57:846-9. 2002
    ..We performed VUS and VCUG simultaneously with the total time for both examinations taking no longer than the time required for either examination individually...
  34. ncbi Simultaneous voiding cystourethrography and voiding urosonography
    M Uhl
    Department of Pediatric Radiology, Freiburg University Hospital, Germany
    Acta Radiol 44:265-8. 2003
    ..To compare the diagnostic accuracy of contrast-enhanced voiding urosonography (VUS) and voiding cystourethrography (VCUG) during simultaneous performance of both examinations...
  35. ncbi Intrarenal reflux: diagnosis with contrast-enhanced harmonic US
    Kassa Darge
    Department of Pediatric Radiology, Wuerzburg University Hospital, Josef Schneider Strasse 2, 97080, Wuerzburg, Germany
    Pediatr Radiol 33:729-31. 2003
    ..Moreover, at the height of the reflux the right kidney parenchyma turned markedly echogenic, corresponding to massive IRR. The voiding cystourethrography that followed confirmed the results of the VUS...
  36. ncbi Cyclic voiding urosonography in detecting vesicoureteral reflux in children
    Gregor Novljan
    Department of Pediatric Nephrology, University Medical Center Ljubljana, Children s Hospital, Stare pravde 4, 1000 Ljubljana, Slovenia
    Pediatr Nephrol 18:992-5. 2003
    ..Cyclic VUS detected 25% more VURs than the conventional (one cycle only) VUS ( P=0.049) and revealed 50% more VUR III than the first cycle. Our results suggest that cyclic VUS is superior to conventional VUS...
  37. ncbi Cystography in infants and children: a critical appraisal of the many forms with special regard to voiding cystourethrography
    Michael Riccabona
    Department of Radiology, Division of Pediatric Radiology, University Hospital Graz, LKH Graz, Auebruggenplatz, 8036 Graz, Austria
    Eur Radiol 12:2910-8. 2002
    ....
  38. ncbi Vesicoureteral reflux in infants with isolated antenatal hydronephrosis
    Veronique Phan
    Division of Nephrology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Nephrol 18:1224-8. 2003
    ..567 and P=0.802). VUR was detected in 15% of children with isolated ANH, many of whom had normal postnatal US or mild postnatal pelviectasis. VCUG is the only reliable test for detecting postnatal VUR...
  39. ncbi Comparison of echo-enhanced ultrasound with fluoroscopic MCU for the detection of vesicoureteral reflux in neonates
    Rachael L McEwing
    Department of Radiology, Christchurch Hospital, Christchurch, New Zealand
    Pediatr Radiol 32:853-8. 2002
    ..It involves ionizing radiation. This study was designed to assess the efficacy of contrast-enhanced sonography in predicting the presence or absence of VUR...
  40. ncbi Cystosonography and voiding cystourethrography in the diagnosis of vesicoureteral reflux
    Giorgio Piaggio
    Department of Nephrology, Dialysis, and Transplantation, Scientific Directorate, G Gaslini Institute, Largo Gerolamo Gaslini 5, 16148 Genoa, Italy
    Pediatr Nephrol 18:18-22. 2003
    ..Further improvements of CSG, both in US contrast media and in US technique, could possibly increase its sensitivity...
  41. ncbi Harmonic US imaging of vesicoureteric reflux in children: usefulness of a second generation US contrast agent
    Giorgio Ascenti
    Department of Radiological Sciences, University of Messina, Via Giordano Bruno, 53, 98163 Messina, Italy
    Pediatr Radiol 34:481-7. 2004
    ..Contrast-enhanced voiding urosonography (VUS) is largely accepted both for the diagnosis and follow-up of vesicoureteric reflux (VUR) in children...
  42. pmc Urinary tract infection: is there a need for routine renal ultrasonography?
    G Zamir
    Pediatric Department A, Ha Emek Medical Center, Afula, Israel
    Arch Dis Child 89:466-8. 2004
    ..To assess the yield of routine renal ultrasound (RUS) in the management of young children hospitalised with first uncomplicated febrile urinary tract infection (UTI)...
  43. ncbi The role of infection and free oxygen radical damage in reflux nephropathy: an experimental study
    Hamit Okur
    Department of Pediatric Surgery, Erciyes University Medical School, Kayseri, Turkey
    J Urol 169:1874-7. 2003
    ..We compared the effects of sterile and infected urine on reflux nephropathy in rabbits with experimental vesicoureteral reflux...
  44. ncbi Laparoscopic extravesical transperitoneal approach for vesicoureteral reflux
    Mario Riquelme
    Department of General Surgery, Christus Muguerza Hospital, Monterrey, NL, Mexico
    J Laparoendosc Adv Surg Tech A 16:312-6. 2006
    ..Laparoscopy may have a place in the treatment of vesicoureteral reflux. In this study, we present the results of laparoscopic extravesical transperitoneal treatment in 15 children (19 ureters) of vesicoureteral reflux...
  45. ncbi Echo-enhanced color Doppler cystosonography of vesicoureteral reflux in children. Improvement by stimulated acoustic emission
    M Riccabona
    Department of Radiology, Division of Pediatric Radiology, University Hospital, Graz, Austria
    Acta Radiol 44:18-23. 2003
    ..To prospectively evaluate the potential of echo-enhanced color Doppler sonography (ee-CDS) using the acoustic stimulated emission technique in the diagnosis of vesicoureteral reflux (VUR) in children...
  46. ncbi Low contrast dose voiding urosonography in children with phase inversion imaging
    Andrea Kopitzko
    Department of Radiology and Nuclear Medicine, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    Eur Radiol 14:2290-6. 2004
    ..It allowed a reduction of contrast dose and cost by approximately 35% over current dose recommendations for fundamental US...
  47. pmc Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux
    Weining Lu
    Genetics Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Hum Genet 80:616-32. 2007
    ..Adult heterozygous and mosaic mutant mice with reduced Robo2 gene dosage also exhibit striking CAKUT-VUR phenotypes. Collectively, these results implicate the SLIT-ROBO signaling pathway in the pathogenesis of a subset of human VUR...
  48. ncbi A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34
    Kalyani R Vats
    Department of Pediatrics, Division of Pediatric Nephrology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Am Soc Nephrol 17:1158-67. 2006
    ..Herein is reported a new locus on chromosome 13q33q34 that can be associated with VUR with several genes showing mRNA expression patterns that suggest their potential for involvement in renal/urinary tract developmental anomalies...
  49. ncbi Indirect voiding urosonography for detecting vesicoureteral reflux in children
    Matjaz Kopac
    Department of Pediatric Nephrology, University Children s Hospital, University Medical Centre Ljubljana, Stare pravde 4, 1000 Ljubljana, Slovenia
    Pediatr Nephrol 20:1285-7. 2005
    ..Considering the obstacles in conducting the investigation and its relatively low overall sensitivity and specificity, it seems that IVUS is not sufficiently reliable to replace echo-enhanced VUS...
  50. ncbi Usefulness of echocystography in the study of vesicoureteral reflux
    I Escape
    Servei de Radiologia, Sociedad Cooperativa de Instalaciones Asistenciales Sanitarias, Hospital de Barcelona, Spain
    J Ultrasound Med 20:145-9. 2001
    ..Its ability to detect reflux is similar to that of cystography in cases of high-grade reflux, and it may be an appropriate complementary technique to voiding cystourethrography, because it avoids exposure to radiation...
  51. ncbi Diagnosis of vesicoureteral reflux with ultrasonography
    Kassa Darge
    Department of Pediatric Radiology, Heidelberg University Hospital, Heidelberg, Germany
    Pediatr Nephrol 17:52-60. 2002
    ..The whole field of sonographic diagnosis of reflux is still in the process of rapid development...
  52. ncbi Endoscopic cross-trigonal ureteral reimplantation under carbon dioxide bladder insufflation: a novel technique
    C K Yeung
    Division of Paediatric Surgery, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
    J Endourol 19:295-9. 2005
    ....
  53. ncbi Familial vesicoureteral reflux: testing replication of linkage in seven new multigenerational kindreds
    Simone Sanna-Cherchi
    Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, 630 W 168th Street, P and S 10 432 New York, NY 10032, USA
    J Am Soc Nephrol 16:1781-7. 2005
    ....
  54. ncbi Timing of follow-up voiding cystourethrogram in children with primary vesicoureteral reflux: development and application of a clinical algorithm
    Matthew Thompson
    Section of Nephrology, Children s Mercy Hospital, University of Missouri, Kansas City, Missour 64108, USA
    Pediatrics 115:426-34. 2005
    ..The objective of this study was to develop a clinically applicable algorithm for the optimal timing of repeat VCUGs and validate this algorithm in a retrospective cohort of children with VUR...
  55. ncbi Sterile vesicoureteral reflux decreases tubular cell apoptosis in rat kidney
    Sezgin Guvel
    Department of Urology, Baskent University Faculty of Medicine, Adana Teaching and Medical Research Center, Adana, Turkey
    Urology 65:1244-8. 2005
    ..To assess the possible role of apoptosis in reflux-related renal scarring by investigating how sterile vesicoureteral reflux affects apoptosis of glomerular and tubular cells in the rat kidney...
  56. ncbi Cyclic contrast-enhanced harmonic voiding urosonography for the evaluation of reflux. Can we keep the cost of the examination low?
    Frederica Papadopoulou
    Department of Clinical Radiology and Imaging, Ioannina University Hospital, Ioannina, 45110, Greece
    Eur Radiol 16:2521-6. 2006
    ..A second cycle of contrast-enhanced harmonic VUS with no added CM discloses significantly more cases of VUR at no additional cost for the examination...
  57. pmc Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux
    P Hu
    Epithelial Biology Unit, The Ronald O Perelman Department of Dermatology, New York, New York 10016, USA
    J Cell Biol 151:961-72. 2000
    ..Studies of VUR in animal models caused by well-defined genetic defects should lead to improved molecular classification, prenatal diagnosis, and therapy of this important hereditary problem...
  58. pmc Primary, nonsyndromic vesicoureteric reflux and its nephropathy is genetically heterogeneous, with a locus on chromosome 1
    S A Feather
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London WC1N 1EH, United Kingdom
    Am J Hum Genet 66:1420-5. 2000
    ..Our results support the hypothesis that VUR is a genetic disorder...
  59. ncbi Contrast-enhanced gray-scale and color Doppler voiding urosonography versus voiding cystourethrography in the diagnosis and grading of vesicoureteral reflux
    A L Valentini
    Department of Radiology, , Rome, Italy
    J Clin Ultrasound 29:65-71. 2001
    ..CONCLUSIONS: The use of color Doppler imaging significantly improves the accuracy of contrast voiding urosonography in the detection and grading of VUR...
  60. ncbi How to perform the perfect voiding cystourethrogram
    Seema Agrawalla
    Department of Radiology, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Pediatr Radiol 34:114-9. 2004
    ..Because of this, we have undertaken a comprehensive literature review of various aspects of the test in order to determine the best way to perform the VCUG in modern paediatric radiology practice...
  61. ncbi Does urinary tract ultrasonography at hospitalization for acute pyelonephritis predict vesicoureteral reflux?
    W H Foresman
    University of Rochester School of Medicine, Rochester, New York, USA
    J Urol 165:2232-4. 2001
    ..We evaluate the correlation between urinary tract ultrasound during hospitalization for acute pyelonephritis with subsequent voiding cystourethrography in children...
  62. ncbi Laparoscopic cross-trigonal Cohen ureteroneocystostomy: novel technique
    I S Gill
    Section of Laparoscopic and Minimally Invasive Surgery, Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Urol 166:1811-4. 2001
    ..Potential advantages include a decreased hospital stay, decreased narcotic requirement and better cosmesis. Further experience is necessary to refine the technical nuances and evaluate outcomes compared to the open technique...
  63. ncbi Cyclic cystography: diagnostic yield in selected pediatric populations
    M J Gelfand
    Department of Radiology, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Radiology 213:118-20. 1999
    ..To test the hypothesis that the diagnostic yield of cyclic cystography is related to the prevalence of vesicoureteral reflux (VUR) in the population being evaluated...
  64. ncbi Cyclic voiding urosonography for detecting vesicoureteric reflux in renal transplant recipients
    R B Kenda
    Department of Pediatric Nephrology, University Medical Center Ljubljana, Ljubljana, Slovenia
    Nephrol Dial Transplant 16:2229-31. 2001
    ..The sensitivity of X-ray and radionuclide cystography for detecting VUR may be improved with cyclic procedures. The aim of our study was to evaluate whether cyclic VUS is superior to the single-cycle procedure...
  65. ncbi Interaction of normal saline solution with ultrasound contrast medium: significant implication for sonographic diagnosis of vesicoureteral reflux
    Kassa Darge
    Department of Pediatric Radiology, Institute of Radiodiagnostic, Würzburg University Hospital, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Eur Radiol 13:213-8. 2003
    ..For the purpose of filling the bladder during contrast-enhanced voiding urosonography only normal saline solution from non-vacuum-sealed containers should be used. For practical purposes, normal saline from plastic containers is safest...
  66. ncbi Laparoscopic extravesical reimplantation for postpubertal vesicoureteral reflux
    Tung Shu
    Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Endourol 18:441-6. 2004
    ..In the adolescent group, its repair can be a challenging open procedure. We present our preliminary experience with laparoscopic extravesical ureteral reimplantation for postpubertal vesicoureteral reflux...
  67. ncbi Clinical course of prenatally detected primary vesicoureteral reflux
    José Maria Penido Silva
    Paediatric Nephrourology Unit, Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, M G, Brazil
    Pediatr Nephrol 21:86-91. 2006
    ..Our study corroborates the results obtained in other series of infants with reflux that emphasized the heterogeneity of this disorder...
  68. ncbi Contrast-enhanced sonographic detection of vesicoureteral reflux in children: comparison with voiding cystourethrography
    K Vassiou
    Department of Radiology, University of Thessalia, Larissa, Greece
    Rofo 176:1453-7. 2004
    ..Prospective evaluation of contrast-enhanced sonography (CES) as an alternative to radiographic voiding cystourethrography (VCUG) in the detection of vesicoureteral reflux (VUR)...
  69. ncbi Diagnosis of vesicoureteric reflux with low-dose contrast-enhanced harmonic ultrasound imaging
    Kassa Darge
    Department of Paediatric Radiology, University Hospital Wuerzburg, Josef Schneider Strasse 2 D31, 97080 Wuerzburg, Germany
    Pediatr Radiol 35:73-8. 2005
    ..Harmonic US imaging has been shown to be better than conventional US for the detection and visualisation of microbubbles in contrast-enhanced voiding urosonography (VUS)...
  70. ncbi Antenatal renal pelvis dilatation emphasizing vesicoureteric reflux: two-year follow-up of minor postnatal dilatation
    H Kapadia
    Sachs Children s Hospital and Department of Obstetrics and Gynecology, Stockholm, Sweden
    Acta Paediatr 93:336-9. 2004
    ..To describe the occurrence of foetal renal pelvis dilatation in an unselected population of pregnancies and to describe the clinical course in a subgroup of infants with minor renal pelvis dilatation (RPD)...
  71. ncbi Natural history of vesicoureteral reflux associated with kidney anomalies
    Nino Guarino
    Division of Pediatric Urology, Ospedale Infantile Regina Margherita, Turin, Italy
    Urology 65:1208-11. 2005
    ..To evaluate the cystographic follow-up of patients with multicystic dysplastic kidney (MCDK), renal agenesis, and renal ectopia with associated primary vesicoureteral reflux (VUR)...
  72. ncbi Voiding cystourethrosonography for the diagnosis of vesicoureteral reflux in a developing country
    Rezar Xhepa
    Pediatric Nephrology Service, University Hospital Center Mother Teresa, Tirana, Albania
    Pediatr Nephrol 19:638-43. 2004
    ..The potential limiting factors of the technique include the operator's training and experience and the costs of the contrast medium...
  73. ncbi Follow-up of unilateral multicystic kidney dysplasia after prenatal diagnosis
    F Eckoldt
    Klinik und Poliklinik for Kinderchirurgie, der Medizinischen Fakultät Charité der Humboldt Universität zu Berlin, Germany
    J Matern Fetal Neonatal Med 14:177-86. 2003
    ..We analyze our own experience and demonstrate a management regime based on these results and existing studies...
  74. ncbi No pathogenic mutations in the uroplakin III gene of 25 patients with primary vesicoureteral reflux
    Jacques C Giltay
    Department of Medical Genetics, University Medical Center Utrect, The Netherlands
    J Urol 171:931-2. 2004
    ..Therefore, the UPIII gene was sequenced to see if any mutations could be detected in patients with primary VUR...
  75. ncbi Simultaneous voiding cystourethrography and voiding urosonography reveals utility of sonographic diagnosis of vesicoureteral reflux in children
    M Nakamura
    Department of Clinical Laboratory Medicine, Jichi Medical School, Tochigi, Japan
    Acta Paediatr 92:1422-6. 2003
    ....
  76. ncbi Detection of vesico-ureteric reflux in children by colour-flow Doppler ultrasonography
    A Kosar
    Department of Urology, University of Suleyman Demirel, Medical School, Isparta, Turkey
    BJU Int 91:856-9. 2003
    ..To assess the findings of colour-flow Doppler ultrasonography (DUS) in the diagnosis of vesico-ureteric reflux (VUR), as an alternative to the primary diagnostic tool, voiding cysto-urethrography (VCUG)...
  77. ncbi Histopathological evidence of poor prognosis in patients with vesicoureteral reflux
    M Tada
    Second Department of Pathology, School of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan
    Pediatr Nephrol 16:482-7. 2001
    ..These changes may lead to FSGS due to podocyte injury in patients with VUR, with subsequent deterioration of renal function...
  78. ncbi Contrast-enhanced harmonic imaging for the diagnosis of vesicoureteral reflux in pediatric patients
    K Darge
    Department of Pediatric Radiology, Radiological Clinic, Ruprecht-Karls University Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany
    AJR Am J Roentgenol 177:1411-5. 2001
    ..When both fundamental and harmonic imaging options are available, we recommend harmonic imaging for contrast-enhanced sonographic diagnosis of vesicoureteral reflux...
  79. ncbi Comprehensive ultrasound versus voiding cysturethrography in the diagnosis of vesicoureteral reflux
    Oliver J Muensterer
    Department of Paediatric, Duke University Medical Center, Duham, North Carolina, USA
    Eur J Pediatr 161:435-7. 2002
    ..Taking abnormal kidney length into account as well, dilative VUR was diagnosed by ultrasound with a sensitivity of 92% (95% CI 82%-100%) and a sensitivity of 67% (95% CI 63%-72%), P<0.001...
  80. ncbi The development of a pig model to study fetal vesico-ureteric reflux
    P A Dewan
    Urology Unit, Royal Children s Hospital, University of Melbourne, Parkville, Victoria, Australia
    BJU Int 86:1054-7. 2000
    ..To develop a surgical protocol to induce vesico-ureteric reflux (VUR) in utero by ablating the ureteric tunnel in a fetal pig model...
  81. ncbi Outcome of sibling vesicoureteral reflux
    Dipen J Parekh
    Division of Pediatric Urology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Urol 167:283-4. 2002
    ..We determine the efficacy of a prospective screening analysis of an asymptomatic sibling of patients with reflux...
  82. ncbi Natural history of neonatal reflux associated with prenatal hydronephrosis: long-term results of a prospective study
    Jyoti Upadhyay
    Division of Urology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Urol 169:1837-41; discussion 1841; author reply 1841. 2003
    ..We have previously reported on patients with neonatal vesicoureteral reflux followed conservatively. The current study is a long-term followup of our prospective expectant management protocol for the overall cohort...
  83. ncbi Sibling vesicoureteral reflux in multiple gestation births
    M Kaefer
    Department of Urology, Children s Hospital and Harvard Medical School, Boston, MA, USA
    Pediatrics 105:800-4. 2000
    ..We report the incidence of VUR in siblings of multiple gestation births and for the first time compare the relative incidence of reflux between identical and fraternal twins...
  84. ncbi Genetic evidence for a novel gene(s) involved in urogenital development on 10q26
    T Ogata
    Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
    Kidney Int 58:2281-90. 2000
    ..In this study, we examined genotype-phenotype correlations in patients with distal 10q monosomy...
  85. ncbi Impact of early screening for reflux in siblings on the detection of renal damage
    Anne Marie Houle
    Urology Division, Hopital Sainte Justine, Montreal, Quebec, Canada
    BJU Int 94:123-5. 2004
    ....
  86. ncbi Contrast-enhanced ultrasound voiding cystography as a screening examination for vesicoureteral reflux in the follow-up of renal transplant recipients: a new approach
    A Kmetec
    Department of Urology, University Medical Centre, Ljubljana, Slovenia
    Nephrol Dial Transplant 16:120-3. 2001
    ..CONCLUSION: In our preliminary study, contrast-enhanced USVC has proved to be an effective examination, with the same accuracy rate as RVC in detecting grade III VUR episodes with low diagnostic accuracy for low reflux grades...
  87. ncbi Susceptibility to vesicoureteral reflux in Japanese is linked to HLA-DR antigen
    A Kawauchi
    Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Urology 58:1036-40. 2001
    ..To determine whether vesicoureteral reflux is associated with the human leukocyte antigen (HLA) genes...
  88. ncbi Spontaneous resolution rates of vesicoureteral reflux in Brazilian children: a 30-year experience
    Miguel Zerati Filho
    Division of Urology, Sao Paulo State University, UNESP, Botucatu, Sao Paulo, Brazil
    Int Braz J Urol 33:204-12; discussion 213-5. 2007
    ..We evaluated clinical characteristics of primary vesicoureteral reflux (VUR) in infants in a 30-year period in Brazil with special reference to the relation of renal parenchymal damage to urinary tract infection and gender...
  89. ncbi Immature ureteric jet doppler patterns and urinary tract infection and vesicoureteric reflux in children
    Vivian Yee Fong Leung
    Diagnostic Radiology and Organ Imaging Department, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Ultrasound Med Biol 28:873-8. 2002
    ..5%) and VUR (90.5%) groups than in the healthy controls. The difference was statistically significant (p = 0.0005 for both). The persistence of this immature pattern was highly associated with UTI and VUR...
  90. ncbi Ureteroneocystostomy in children with posterior urethral valves: indications and outcome
    M T El-Sherbiny
    Urology and Nephrology Center, Mansoura, Eygpt
    J Urol 168:1836-9; discussion 1839-40. 2002
    ..Ureteroneocystostomy in children with posterior urethral valves represents a surgical challenge. We reviewed our experience with this procedure to assess its indications and outcome...
  91. ncbi Renal pelvic wall thickening in childhood urinary tract infections--evidence of acute pyelitis or vesicoureteral reflux?
    You Lin Tain
    Division of Pediatric Nephrology, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan
    Scand J Urol Nephrol 37:28-30. 2003
    ....
  92. ncbi Endoscopic treatment of vesicoureteral reflux with autologous chondrocytes: postoperative sonographic features
    Harriet J Paltiel
    Department of Radiology, Children s Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
    Radiology 232:390-7. 2004
    ....
  93. ncbi Long-term evolution of renal damage associated with unilateral vesicoureteral reflux
    Cesare Polito
    Department of Pediatrics, Second University of Naples, Naples, Italy
    J Urol 178:1043-7; discussion 1047. 2007
    ..We determined the long-term evolution of renal damage associated with vesicoureteral reflux...
  94. ncbi Cyclic voiding cystourethrography: is vesicoureteral reflux missed with standard voiding cystourethrography?
    Frederica Papadopoulou
    Department of Radiology, Hippokration General Hospital, Thessaloniki, Greece
    Eur Radiol 12:666-70. 2002
    ..5%). In conclusion, intermittent VUR occurred in up to 23% of children undergoing VCUG. In more than one-third of them VUR was of major degree. Cyclic VCUG can enhance the ability of the method to detect and grade reflux...
  95. ncbi Is ureteral reimplantation necessary during augmentation cystoplasty in patients with neurogenic bladder and vesicoureteral reflux?
    Nasser Simforoosh
    Urology Nephrology Branch, Dr Labbafi nejad Hosptial, Tehran, Islamic Republic of Iran
    J Urol 168:1439-41. 2002
    ..We assessed the outcome of vesicoureteral reflux after augmentation cystoplasty in patients with neurogenic bladder...
  96. ncbi Factors affecting renal scar development in children with spina bifida
    S K Ozel
    Department of PediatricUrology, Ege University Faculty of Medicine, Izmir, Turkey
    Urol Int 79:133-6. 2007
    ..Prevention of renal scarring is the main therapeutic goal in children with spina bifida. We aimed to determine factors affecting renal scar development in these patients...
  97. ncbi [Functional disorders of the lower urinary tract in children]
    R Fotter
    Klinische Abteilung für Kinderradiologie, Radiologische Univ Klinik Graz
    Radiologe 45:1085-91. 2005
    ..Imaging procedures in addition to urodynamic methods are of decisive importance for diagnosis and treatment, but noninvasive approaches such as sonography should be given preference...
  98. ncbi Abnormal dimercapto-succinic acid scans predict an increased risk of breakthrough infection in children with vesicoureteral reflux
    Gerald C Mingin
    Department of Urology and Pediatrics, University of California San Francisco, San Francisco Children s Hospital, 400 Parnassus Avenue, San Francisco, CA 94143, USA
    J Urol 172:1075-7; discussion 1077. 2004
    ..We sought to determine if technetium dimercapto-succinic acid (DMSA) scan could help predict which children are at risk for breakthrough urinary tract infection...
  99. ncbi Timing of voiding cystourethrogram after urinary tract infection
    P Sathapornwajana
    Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand
    Arch Dis Child 93:229-31. 2008
    ..3% (17.4%-31.2%) of those for whom it was performed 7 days (n = 148) after diagnosis. There was no statistically significant difference in reflux prevalence between these two groups...
  100. ncbi Magnetic resonance voiding cystography in the diagnosis of vesicoureteral reflux: comparative study with voiding cystourethrography
    Sang Kwon Lee
    Department of Radiology, Dongsan Medical Center, Keimyung University College of Medicine, Taegu, Korea
    J Magn Reson Imaging 21:406-14. 2005
    ..To evaluate the feasibility of magnetic resonance voiding cystography (MRVC) compared with voiding cystourethrography (VCUG) for detecting and grading vesicoureteral reflux (VUR)...
  101. ncbi Plasma and urinary adrenomedullin levels in children with renal parenchymal scar and vesicoureteral reflux
    Suleyman Kalman
    Division of Nephrology, Department of Pediatrics, Gazi University, Besevler Ankara, Turkey
    Pediatr Nephrol 20:1111-5. 2005
    ..05 and P >0.05, respectively). The finding that diminished urinary AM levels in patients with RPS and VUR implies that AM can be a prognostic factor in the long-term follow-up of cases with these diseases...

Research Grants35

  1. Clinical Outcomes for Siblings of Children with Vesico-Ureteral Reflux
    CALEB PENNELL NELSON; Fiscal Year: 2013
    ..abstract_text> ..
  2. Genetic Variations and Development of Vesicoureteral Reflux and Sequelae
    DAVID SULLIVAN HAINS; Fiscal Year: 2010
    ..Also, we will investigate potential genetic causes of vesicoureteral reflux. ..
  3. Genetic Analysis of Etv4/Etv5 Transcription Factors and Kidney Development
    FRANKLIN D COSTANTINI; Fiscal Year: 2013
    ..Lack of Adamts16 and/or 18 may cause reduced nephron number and hyper- tension. We test this by examining kidney development, nephron number and blood pressure in mutant mice. ..
  4. Producing micturition by combined afferent and effernet electrical stimulation
    Kenneth J Gustafson; Fiscal Year: 2010
    ....
  5. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2012
    ..Our new approach also preserves the spinal reflex functions for bowel and sexual organ, and more importantly provides people with SCI the opportunity to benefit from advances in neural regeneration and repair techniques in the future. ..
  6. Molecular Pathogenesis of Vesicoureteral Reflux
    Weining Lu; Fiscal Year: 2012
    ..Understanding the underlying pathogenic mechanism of VUR and reflux nephropathy will provide novel approaches to detect patients at risk and identify novel therapeutic strategies. ..
  7. Molecular Events in Urinary Tract Formation
    CATHY LEE MENDELSOHN; Fiscal Year: 2012
    ..These findings should help in our general understanding of the abnormalities underlying urinary tract birth defects in humans and may help to identify new ways to intervene or repair urinary tract malformations in newborns. ..
  8. Discovering Human Birth Defect Genes from Chromosomal Rearrangements
    Richard L Maas; Fiscal Year: 2013
    ....
  9. A genetic model of vesicoureteral reflux and reflux nephropathy
    CARLTON MATTHEW BATES; Fiscal Year: 2012
    ..We have a mouse mutant that develops reflux and subsequent reflux nephropathy. This mouse model will help us determine how best to treat children with this condition. ..
  10. RIVUR Study
    Tej K Mattoo; Fiscal Year: 2012
    ..abstract_text> ..
  11. Limited Competition for Continuation of RIVUR
    SAUL PHILIP GREENFIELD; Fiscal Year: 2012
    ..It is anticipated that data from the RIVUR trial will enable appropriate treatment and utilization of health care resources for children with VUR. ..
  12. Randomized Intervention for Vesico-Ureteral Reflux (RIVUR) Trial
    Ming Hsien Wang; Fiscal Year: 2012
    ..As of October 2009, 370 children have been recruited into the study and are being followed for 2 years. The primary aim of the extension is to complete recruitment and follow-up of the study cohort. ..
  13. Randomized Intervention for Vesicoureteral Reflux (RIVUR)
    Myra A Carpenter; Fiscal Year: 2012
    ..DCC investigators and staff will initiate, participate in, and support manuscript writing groups. ..
  14. Randomized Intervention for VesicolUreteral Reflux (RIVUR) Study
    Ron Keren; Fiscal Year: 2012
    ..abstract_text> ..
  15. Regulation of Bladder Smooth Muscle Hyperplasia
    Paul Austin; Fiscal Year: 2007
    ..Work of this nature may decrease the morbidity and mortality that is caused by bladder outlet obstruction. ..
  16. Regulation of Skp2 Expression in Urinary Bladder Wall
    STEVEN WEINTRAUB; Fiscal Year: 2005
    ..These studies will be aimed at identifying targets for intervention to inhibit the hypertrophic response of the bladder wall that occurs in response to bladder outlet obstruction. ..
  17. Risk factors for renal scarring in children after urinary tract infection
    Ron Keren; Fiscal Year: 2012
    ..PROJECT NARRATIVE Understanding which children are at the greatest risk of renal scarring after a UTI will allow clinicians to provide more targeted therapies and interventions to prevent this adverse outcome. ..
  18. RIVUR - Randomized Intervention for Children with Vesicoureteral Reflux
    Alejandro Hoberman; Fiscal Year: 2012
    ..Our retention of children is evidenced by rates above 95% overall in completion of data collection forms throughout the study. ..
  19. Genetic Determinants of Vesicoureteral Reflux
    Ali Gharavi; Fiscal Year: 2007
    ..Identification of genes underlying VUR will provide novel approaches to detect patients at risk and may enable the development of novel therapeutic approaches for this disorder [unreadable] [unreadable]..
  20. IMMUNIZATION AGAINST URINARY TRACT INFECTION
    DAVID UEHLING; Fiscal Year: 2001
    ..2. Utilize an animal model to clarify the immunologic basis for the increased resistance to UTI following vaginal immunization and to evaluate adjuvants and vaccination regimes that optimize immunogenicity and efficacy of UTI vaccines. ..
  21. Genetic Epidemiology Of Kidney Anomalies
    Abhay Vats; Fiscal Year: 2004
    ..We wish to pursue further gene localization studies on chromosome 13 in this application in order to identify the causative genes. ..
  22. INTERNATIONAL WORKSHOP ON REFLUX AND PYELONEPHRITIS
    James Roberts; Fiscal Year: 1991
    ....
  23. BLADDER INFECTION AND REFLUX NEPHROPATHY
    CECIL HODSON; Fiscal Year: 1980
    ..It is anticipated raised bladder pressure will ensue within days of establishing infection...
  24. Tacrolimus and Plasmapheresis in Treatment-Resistant FSGS
    Tej Mattoo; Fiscal Year: 2007
    ..The proposed study will offer new treatment options in such patients and save many from the pain and the distress of undergoing dialysis and renal transplantation. [unreadable] [unreadable] [unreadable]..
  25. Role of FGF Receptors in the Developing Kidney
    Carlton Bates; Fiscal Year: 2009
    ..Finally, complementary in vitro and in vitro assays will be performed to determine the FGFR downstream signaling pathways relevant to kidney development. ..
  26. Prediciting Severe Neonatal Hyperbilirubinemia
    Ron Keren; Fiscal Year: 2007
    ....
  27. Insulin Producing Cells from Amniotic Stem Cells for Diabetes Therapy
    Anthony Atala; Fiscal Year: 2009
    ..Successful development of an abundant source of transplantable insulin producing cells potentially would have a profound impact on the treatment of a major public health problem. ..
  28. ROLE OF STRETCH-INDUCED COX-2 IN BLADDER CONTRACTILITY
    John Park; Fiscal Year: 2003
    ..Therefore, characterizing the biological role of PG synthetic pathways via COX-2 gene activation in bladder should lead to novel insights in the overall management of painful bladder syndromes. ..
  29. BIOENGINEERING OF BLADDER TISSUES
    Anthony Atala; Fiscal Year: 2003
    ..In this aim we will attempt to determine the phenotypic and functional characteristics, over time, of the bioengineered bladder tissues, as compared to controls. ..
  30. Urinary Biomarkers for Steroid Resistant Nephrotic Syndr
    Robert Mak; Fiscal Year: 2005
    ..We believe that data from the current study will improve our diagnostic and therapeutic strategy and may provide clues to the pathogenetic significance of the identified biomarkers. ..
  31. Molecular Analysis of Ureteric Reflux
    Robert Mak; Fiscal Year: 2006
    ..A clinical database of primary VUR and RN will be set up to establish correlations between biomarkers and phenotype and to test the sensitivity and specificity of these markers for detecting primary VUR and RN. ..
  32. Bone Marrow Stromal Cells for Bladder Tissue Engineering
    Yuanyuan Zhang; Fiscal Year: 2006
    ..3.3) Evaluate extent of bladder regeneration at different time points through histology, contractility assays, and immunohistochemical staining. [unreadable] [unreadable] [unreadable]..
  33. Bladder-specific Knockout and Gene Expression
    Xue ru Wu; Fiscal Year: 2009
    ..These studies will generate powerful experimental tools for studying bladder biology and diseases and offer molecular insights regarding urothelial growth and tumorigenesis. ..