orchitis

Summary

Summary: Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.

Top Publications

  1. ncbi West Nile virus encephalitis with myositis and orchitis
    Roger D Smith
    Department of Pathology and Laboratory Medicine, Universityof Cincinnati Medical Center, OH 45267 0529, USA
    Hum Pathol 35:254-8. 2004
  2. ncbi Brucellar epididymo-orchitis in southeastern part of Turkey: an 8 year experience
    Mustafa Kemal Celen
    Department of Infectious Diseases and Clinic Microbiology, Medical School, Dicle University, Diyarbakir, Turkey, 21280
    Braz J Infect Dis 14:109-15. 2010
  3. ncbi Chronic orchitis: a neglected cause of male infertility?
    H C Schuppe
    Centre of Dermatology and Andrology, Justus Liebig University, Giessen, Germany
    Andrologia 40:84-91. 2008
  4. ncbi Patterns of infiltration of lymphocytes into the testis under normal and pathological conditions in mice
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, Tokyo, Japan
    Am J Reprod Immunol 59:55-61. 2008
  5. ncbi Mechanism of infertility in male guinea pigs immunized with sperm PH-20
    K S Tung
    Department of Pathology and Microbiology, University of Virginia, Charlottesville 22908, USA
    Biol Reprod 56:1133-41. 1997
  6. ncbi Mumps
    Anders Hviid
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Lancet 371:932-44. 2008
  7. ncbi Testicular autoimmunity
    Patricia Jacobo
    Institute for Research in Reproduction, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    Autoimmun Rev 10:201-4. 2011
  8. pmc Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege
    Sudhanshu Bhushan
    Department of Anatomy and Cell Biology, Unit of Reproductive Biology, Justus Liebig University Giessen, Giessen, Germany
    PLoS ONE 6:e28452. 2011
  9. ncbi Intratesticular expression of mRNAs of both interferon γ and tumor necrosis factor α is significantly increased in experimental autoimmune orchitis in mice
    Hayato Terayama
    Department of Anatomy, Tokyo Medical University, Tokyo, Japan
    J Reprod Dev 57:296-302. 2011
  10. ncbi Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis
    Claudia Rival
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, Piso 10, C1121 ABG Buenos Aires, Argentina
    J Reprod Immunol 70:43-58. 2006

Research Grants

  1. Advanced Nitric Oxide Release Bactericidal Urinary Catheters
    Mark E Meyerhoff; Fiscal Year: 2013
  2. PURIFIED TESTIS ANTIGENS AND TESTICULAR AUTOIMMUNITY
    Kenneth Tung; Fiscal Year: 1991
  3. REGULATION OF E-SELECTIN DURING ACUTE INFLAMMATION
    Kevin Billups; Fiscal Year: 1999
  4. REGULATION OF TESTICULAR BLOOD FLOW
    Claude Desjardins; Fiscal Year: 1993
  5. IMMUNOREGULATORY LOCI IN ORGAN SPECIFIC AUTOIMMUNITY
    Cory Teuscher; Fiscal Year: 2001
  6. BASIC AND CLINICAL RHEUMATOLOGY
    JOEL TAUROG; Fiscal Year: 2005
  7. Autoimmunity and Pathogenesis of Glomerulonephritis
    Harini Bagavant; Fiscal Year: 2010
  8. HLA-B27 and Experimental Spondyloarthropathy
    JOEL TAUROG; Fiscal Year: 2009
  9. Regulatory T cells in Systemic Lupus Erythematosus
    Harini Bagavant; Fiscal Year: 2007
  10. Role of T Cells in Experimental Spondyloarthropathy
    JOEL TAUROG; Fiscal Year: 2002

Detail Information

Publications222 found, 100 shown here

  1. ncbi West Nile virus encephalitis with myositis and orchitis
    Roger D Smith
    Department of Pathology and Laboratory Medicine, Universityof Cincinnati Medical Center, OH 45267 0529, USA
    Hum Pathol 35:254-8. 2004
    ..b>Orchitis with dense T-lymphocyte infiltration and syncytial cell formation thought to be due to WNV were also noted.
  2. ncbi Brucellar epididymo-orchitis in southeastern part of Turkey: an 8 year experience
    Mustafa Kemal Celen
    Department of Infectious Diseases and Clinic Microbiology, Medical School, Dicle University, Diyarbakir, Turkey, 21280
    Braz J Infect Dis 14:109-15. 2010
    the different clinical and laboratory features and response to treatment of patients with acute brucellar epididymo-orchitis (BEO) reporting to the reference hospital in Southeastern Anatolia of Turkey.
  3. ncbi Chronic orchitis: a neglected cause of male infertility?
    H C Schuppe
    Centre of Dermatology and Andrology, Justus Liebig University, Giessen, Germany
    Andrologia 40:84-91. 2008
    ..With regard to their impact on male reproductive function, orchitis and epididymo-orchitis due to local or systemic infection as well as noninfectious aetiological factors are of ..
  4. ncbi Patterns of infiltration of lymphocytes into the testis under normal and pathological conditions in mice
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, Tokyo, Japan
    Am J Reprod Immunol 59:55-61. 2008
    ..Although the physiological function of these penetrating lymphocytes remains unknown, we suppose that this micro-status provides a chance for evocation of autoimmune inflammation of the TR, R and E in some pathological conditions...
  5. ncbi Mechanism of infertility in male guinea pigs immunized with sperm PH-20
    K S Tung
    Department of Pathology and Microbiology, University of Virginia, Charlottesville 22908, USA
    Biol Reprod 56:1133-41. 1997
    ..A second effect was the induction of experimental autoimmune orchitis (EAO), representing the first report of EAO induced by a purified testis/sperm molecule of known functions...
  6. ncbi Mumps
    Anders Hviid
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Lancet 371:932-44. 2008
    ..Aseptic meningitis and encephalitis are common complications of mumps together with orchitis and oophoritis, which can arise in adult men and women, respectively; other complications include deafness and ..
  7. ncbi Testicular autoimmunity
    Patricia Jacobo
    Institute for Research in Reproduction, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    Autoimmun Rev 10:201-4. 2011
    ..Autoimmune orchitis is a model of chronic inflammation useful for elucidating pathogenic mechanisms involved in testicular damage...
  8. pmc Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege
    Sudhanshu Bhushan
    Department of Anatomy and Cell Biology, Unit of Reproductive Biology, Justus Liebig University Giessen, Giessen, Germany
    PLoS ONE 6:e28452. 2011
    ..UPEC-dependent NFAT activation was confirmed in both cultured TM and in TM in an in vivo UPEC infectious rat orchitis model...
  9. ncbi Intratesticular expression of mRNAs of both interferon γ and tumor necrosis factor α is significantly increased in experimental autoimmune orchitis in mice
    Hayato Terayama
    Department of Anatomy, Tokyo Medical University, Tokyo, Japan
    J Reprod Dev 57:296-302. 2011
    Experimental autoimmune orchitis (EAO) is one of the models of immunological male infertility. Murine EAO is CD4+T cell-dependent and classically induced by immunization with a testicular homogenate and adjuvants...
  10. ncbi Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis
    Claudia Rival
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, Piso 10, C1121 ABG Buenos Aires, Argentina
    J Reprod Immunol 70:43-58. 2006
    Experimental autoimmune orchitis (EAO) is an organ-specific model of autoimmunity characterized by an interstitial lymphomononuclear cell infiltrate as well as sloughing and apoptosis of germ cells...
  11. ncbi CD4+ and CD8+ T cells producing Th1 and Th17 cytokines are involved in the pathogenesis of autoimmune orchitis
    Patricia Jacobo
    School of Medicine, Institute for Research in Reproduction, University of Buenos Aires, Paraguay 2155 piso 10, C1121 ABG, Buenos Aires, Argentina
    Reproduction 141:249-58. 2011
    Experimental autoimmune orchitis (EAO) is a useful model to study chronic testicular inflammation and infertility. EAO is characterized by severe damage of seminiferous tubules with germ cells that undergo apoptosis and sloughing...
  12. ncbi Differential changes in CD4+ and CD8+ effector and regulatory T lymphocyte subsets in the testis of rats undergoing autoimmune orchitis
    P Jacobo
    Instituto de Investigaciones en Reproducción, Paraguay 2155, Piso 10, C1121 ABG, Buenos Aires, Argentina
    J Reprod Immunol 81:44-54. 2009
    Experimental autoimmune orchitis (EAO) is a useful model to study organ-specific autoimmunity and chronic testicular inflammation...
  13. ncbi Effect of unilateral testicular rupture on histopathology and germ cell delayed-type hypersensitivity in C3H/He and A/J mice
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, Shinjuku 6 1 1, Tokyo 160 8402, Japan
    J Reprod Immunol 81:55-61. 2009
    Contralateral orchitis induced by unilateral testicular injury has been reported as sympathetic orchitis in men and experimental animals...
  14. ncbi Impaired expression and distribution of adherens and gap junction proteins in the seminiferous tubules of rats undergoing autoimmune orchitis
    C Perez
    Instituto de Investigaciones en Reproducción, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    Int J Androl 34:e566-77. 2011
    Experimental autoimmune orchitis (EAO) is characterized by an interstitial lymphomononuclear cell infiltration and a severe lesion of seminiferous tubules (ST) with germ cells that undergo apoptosis and sloughing...
  15. ncbi Involvement of Fas/Fas-L and Bax/Bcl-2 systems in germ cell death following immunization with syngeneic testicular germ cells in mice
    Maimaiti Kuerban
    Department of Anatomy, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo 160 8402, Japan
    J Androl 33:824-31. 2012
    Experimental autoimmune orchitis (EAO) is characterized by T cell-dependent lymphocytic inflammation and seminiferous tubule damage, which can result in the death of germ cells...
  16. ncbi Caput epididymitis but not orchitis was induced by vasectomy in a murine model of experimental autoimmune orchitis
    Ning Qu
    Department of Anatomy, Tokyo Medical University, Tokyo 160 8402, Japan
    Reproduction 135:859-66. 2008
    ..autoantigens of both round and elongating spermatids, resulting in the development of experimental autoimmune orchitis (EAO)...
  17. ncbi Experimental autoimmune orchitis as a model of immunological male infertility
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, 6 1 1 Shinjuku, Tokyo 160 8402, Japan
    Med Mol Morphol 45:185-9. 2012
    ..Previously, we established an immunological infertility model, experimental autoimmune orchitis (EAO), that can be induced in mice by two subcutaneous injections of viable syngeneic testicular germ cells ..
  18. ncbi Loss of occludin expression and impairment of blood-testis barrier permeability in rats with autoimmune orchitis: effect of interleukin 6 on Sertoli cell tight junctions
    Cecilia Valeria Pérez
    Instituto de Investigaciones Biomedicas, Universidad de Buenos Aires, Buenos Aires, Argentina
    Biol Reprod 87:122. 2012
    ..Experimental autoimmune orchitis (EAO) is characterized by interstitial lymphomononuclear cell infiltration and severe damage of seminiferous ..
  19. ncbi Immune-related disease before and after vasectomy: an epidemiological database study
    M J Goldacre
    Unit of Health Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK
    Hum Reprod 22:1273-8. 2007
    ..We aimed to determine whether men with immune-related diseases were more or less likely than others to have a vasectomy and then to determine whether vasectomy is associated with the subsequent development of immune-related diseases...
  20. ncbi Experimental allergic orchitis in mice. II. Association of disease susceptibility with the locus controlling Bordetella pertussis-induced sensitivity to histamine
    C Teuscher
    Immunogenetics 22:417-25. 1985
    Susceptibility to the induction of murine autoimmune orchitis was found to be associated with the locus controlling Bordetella pertussis-induced sensitivity to the vasoactive amine, histamine...
  21. ncbi Postinflammation stage of autoimmune orchitis induced by immunization with syngeneic testicular germ cells alone in mice
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo, 160 8402, Japan
    Med Mol Morphol 45:35-44. 2012
    We previously established an immunological infertility model, experimental autoimmune orchitis (EAO), which can be induced by two subcutaneous injections of viable syngeneic testicular germ cells on days 0 and 14 in mice without using any ..
  22. ncbi The increasing incidence of mumps orchitis: a comprehensive review
    Niall F Davis
    Department of Urology and Department of Surgery, Mater Misericordiae University Hospital, University College Dublin, Ireland
    BJU Int 105:1060-5. 2010
    There has been a recent increase in mumps orchitis among pubertal and postpubertal males...
  23. ncbi Death receptor and mitochondrial pathways are involved in germ cell apoptosis in an experimental model of autoimmune orchitis
    M S Theas
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    Hum Reprod 21:1734-42. 2006
    Studies on experimental autoimmune orchitis (EAO) have helped to elucidate immunological mechanisms involved in testicular damage...
  24. pmc Post-prostate biopsy infection with Escherichia coli ST131 leading to epididymo-orchitis and meningitis caused by Gram-negative bacilli
    Aris Assimacopoulos
    Sunwest Infusion and Infectious Disease Specialists, Goodyear, Arizona, USA
    J Clin Microbiol 50:4157-9. 2012
    ..prostate biopsy for a rising prostate-specific antigen level developed postbiopsy necrotizing epididymo-orchitis (requiring orchiectomy) and then Gram-negative meningitis, despite fluoroquinolone administration for ..
  25. ncbi Histopathology of the tubuli recti at the start of experimental autoimmune orchitis in mice
    Munekazu Naito
    Department of Anatomy, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo 160 8402, Japan
    Med Mol Morphol 42:230-5. 2009
    We previously established an experimental model of autoimmune orchitis (EAO) by means of immunization with testicular germ cells (TGC) alone in mice and confirmed that the disease can be transferred to mice that had received CD4+ but not ..
  26. ncbi Echo color Doppler findings in postpubertal mumps epididymo-orchitis
    L Tarantino
    Ultrasound Service, D. Cotugno Hospital for Infectious Diseases, Naples, Italy
    J Ultrasound Med 20:1189-95. 2001
    OBJECTIVE: To describe echo color Doppler features of mumps epididymo-orchitis in postpubertal boys and men...
  27. ncbi Mumps orchitis in the post-vaccine era (1967-2009): a single-center series of 67 patients and review of clinical outcome and trends
    Hugo Guillermo Ternavasio-de la Vega
    Internal Medicine Service II, Hospital Universitario of Salamanca, Salamanca, Spain
    Medicine (Baltimore) 89:96-116. 2010
    ..In that period, our institution attended 67 cases of serologically confirmed acute mumps orchitis, the most serious complication of mumps infection in young postpubertal males...
  28. ncbi Testosterone replacement effectively inhibits the development of experimental autoimmune orchitis in rats: evidence for a direct role of testosterone on regulatory T cell expansion
    Monika Fijak
    Department of Anatomy and Cell Biology, Justus Liebig University Giessen, 35385 Giessen, Germany
    J Immunol 186:5162-72. 2011
    ..A common observation in clinical and experimental orchitis as well as in systemic infection and inflammation are decreased levels of testosterone...
  29. ncbi Epididymo-orchitis complicating anorectal malformations: collective review of 41 cases
    Venkatachalam Raveenthiran
    Division of Pediatric Surgery, Rajah Muthiah Medical College, Annamalai University, Tamilnadu, India
    J Urol 186:1467-72. 2011
    Epididymo-orchitis is a devastating complication of imperforate anus. Without proper treatment the condition may result in infertility...
  30. ncbi Three Hsp70 genes are located in the C4-H-2D region: possible candidates for the Orch-1 locus
    M Snoek
    Department of Molecular Genetics, The Netherlands Cancer Institute Antoni van Leeuwenhoek, Amsterdam
    Genomics 15:350-6. 1993
    ..Susceptibility to experimental allergic orchitis, which is controlled by the Orch-1 locus, is one example...
  31. pmc Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis
    N D Meeker
    Department of Microbiology, Brigham Young University, Provo, UT 84602, USA
    Proc Natl Acad Sci U S A 92:5684-8. 1995
    ..better understand the nature and mechanisms of action of these genes, we utilized the murine model of autoimmune orchitis as a prototype...
  32. ncbi Monocyte chemoattractant protein-1 (MCP-1/CCL2) in experimental autoimmune orchitis
    Vanesa A Guazzone
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155 piso 10, C1121 ABG, Buenos Aires, Argentina
    J Reprod Immunol 60:143-57. 2003
    Experimental autoimmune orchitis (EAO) is characterized by an interstitial mononuclear cell infiltrate and a severe lesion of seminiferous tubules with germ cells that undergo apoptosis and sloughing...
  33. ncbi Functional and phenotypic characteristics of testicular macrophages in experimental autoimmune orchitis
    C Rival
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    J Pathol 215:108-17. 2008
    ..Experimental autoimmune orchitis (EAO) is a model of organ-specific autoimmunity and testicular inflammation...
  34. ncbi Identification of immunodominant autoantigens in rat autoimmune orchitis
    Monika Fijak
    Department of Anatomy and Cell Biology, Justus Liebig University of Giessen, D 35385 Giessen, Germany
    J Pathol 207:127-38. 2005
    ..Experimental autoimmune orchitis (EAO) in the rat serves as a model for the investigation of inflammatory testicular impairment...
  35. ncbi Germ cell apoptosis in autoimmune orchitis: involvement of the Fas-FasL system
    Susana Theas
    Centro de Investigaciones en Reproduccion, Facultad de Medicina, Universidad de Buenos Aires, Bs As, Argentina
    Am J Reprod Immunol 50:166-76. 2003
    The aim of this study was to determine the mechanism of germ cell death in experimental autoimmune orchitis (EAO) and the involvement of the Fas-FasL system in this process.
  36. pmc Histamine receptor H1 is required for TCR-mediated p38 MAPK activation and optimal IFN-gamma production in mice
    Rajkumar Noubade
    Department of Medicine, University of Vermont, Burlington, Vermont, USA
    J Clin Invest 117:3507-18. 2007
    ..is a susceptibility gene in both experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune orchitis (EAO), 2 classical T cell-mediated models of organ-specific autoimmune disease...
  37. ncbi Case 91: Tuberculous Epididymo-orchitis
    Malai Muttarak
    Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
    Radiology 238:748-51. 2006
  38. ncbi A common immunoregulatory locus controls susceptibility to actively induced experimental allergic encephalomyelitis and experimental allergic orchitis in BALB/c mice
    C Teuscher
    Department of Veterinary Pathobiology, University of Illinois at Urbana Champaign, Urbana 61802, USA
    J Immunol 160:2751-6. 1998
    ..susceptibility to actively induced experimental allergic encephalomyelitis (EAE) and experimental allergic orchitis (EAO) exists among various BALB/c substrains...
  39. pmc Mumps orchitis
    M Masarani
    Department of Urology, Imperial College of London, Chelsea and Westminster Hospital, London SW10 9NH, UK
    J R Soc Med 99:573-5. 2006
    Although the incidence of mumps orchitis has dramatically declined since the introduction of the childhood vaccination programme, a sharp increase in reported cases of both mumps and mumps orchitis has been seen recently in the UK...
  40. ncbi Brucellar epididymo-orchitis in Saudi Arabia: a retrospective study of 26 cases and review of the literature
    Z A Memish
    Department of Infection Prevention and Control, King Fahad National Guard Hospital, Riyadh, Saudi Arabia
    BJU Int 88:72-6. 2001
    To review the clinical and laboratory features and response to treatment of patients with acute brucellar epididymo-orchitis reporting to a tertiary care hospital in Riyadh, and to compare these with other cases reported previously.
  41. ncbi Trichomonas vaginalis orchitis with associated severe oligoasthenoteratospermia and hypogonadism
    Granville L Lloyd
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Urol 170:924. 2003
  42. ncbi Tubercular epididymo-orchitis masquerading as testicular malignancy: an interesting case
    Ritesh Sachdev
    Acta Cytol 52:511-2. 2008
  43. ncbi Chronic tuberculous epididymo-orchitis manifesting as a non-tender scrotal swelling: magnetic resonance imaging-histological correlation
    Ko Woon Park
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Urology 71:755.e5-7. 2008
    Clinically, chronic tuberculous epididymo-orchitis often is nonspecific and subsequently is indistinguishable from other various scrotal lesions...
  44. pmc The role of tumor necrosis factor-alpha and interleukin-1 in the mammalian testis and their involvement in testicular torsion and autoimmune orchitis
    Jeffrey J Lysiak
    Department of Urology, University of Virginia, Charlottesville, VA 22908, USA
    Reprod Biol Endocrinol 2:9. 2004
    ..IL-1 alpha, and IL-1 beta in the mammalian testis and in two testicular pathologies, testicular torsion and orchitis. TNF alpha in the testis is produced by round spermatids, pachytene spermatocytes, and testicular macrophages...
  45. ncbi Epididymitis and orchitis: an overview
    Thomas H Trojian
    University of Connecticut School of Medicine, Farmington, Connecticut, USA
    Am Fam Physician 79:583-7. 2009
    Epididymitis and orchitis are commonly seen in the outpatient setting. Men between 14 and 35 years of age are most often affected, and Chlamydia trachomatis and Neisseria gonorrhoeae are the most common pathogens in this age group...
  46. ncbi Bacterial LPS-mediated acute inflammation-induced spermatogenic failure in rats: role of stress response proteins and mitochondrial dysfunction
    Mallikarjuna Reddy Metukuri
    Department of Animal Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, AP, India
    Inflammation 33:235-43. 2010
    ..In conclusion, the present study shows the involvement of stress response proteins and mitochondrial dysfunction in LPS-induced germ cell death in male rats...
  47. ncbi Granulomatous epididymo-orchitis, a rare complication of intravesical bacillus Calmette-Guérin therapy for urothelial cancer
    Signe Sofienberg Harving
    Department of Urology, Frederiksberg Hospital, Frederiksberg, Denmark
    Scand J Urol Nephrol 43:331-3. 2009
    Only a few cases of tuberculous epididymo-orchitis after bacillus Calmette-Guérin (BCG) therapy have been published...
  48. ncbi Fine needle aspiration cytology of tubercular epididymitis and epididymo-orchitis
    Shatrughn Prasad Sah
    Department of Pathology, B P Koirala Institute of Health Sciences, Dharan, Nepal
    Acta Cytol 50:243-9. 2006
    To study the role of fine needle aspiration cytology (FNAC) and ancillary studies in the diagnosis of tubercular epididymitis or epididymo-orchitis.
  49. pmc Orchitis and human immunodeficiency virus type 1 infected cells in reproductive tissues from men with the acquired immune deficiency syndrome
    J Pudney
    Department of Obstetrics, Gynecology and Reproductive Biology, Birgham and Women s Hospital, Harvard Medical School, Boston Massachusetts 02115
    Am J Pathol 139:149-60. 1991
    ..There was no evidence of active HIV-1 infection in germ cells or Sertoli cells of the seminiferous tubules or other epithelial cells lining the excurrent ducts or prostatic glands...
  50. ncbi Rapid diagnosis of Brucella epididymo-orchitis by real-time polymerase chain reaction assay in urine samples
    María Isabel Queipo-Ortuño
    Biochemistry and Molecular Biology Department, Faculty of Medicine, University of Malaga, Malaga, Spain
    J Urol 176:2290-3. 2006
    We studied the diagnostic yield of a real-time polymerase chain reaction assay in urine samples for the rapid diagnosis of brucella epididymo-orchitis compared to that of conventional microbiological techniques.
  51. ncbi The management of mumps orchitis
    Tim M Lane
    Department of Urology, Whipps Cross Hospital, London and Queen Mary Westfield School of Medicine, London, UK
    BJU Int 97:1-2. 2006
  52. ncbi Proinflammatory effects of exogenously administered IL-10 in experimental autoimmune orchitis
    Tetsushi Kaneko
    Department of Anatomy, Tokyo Medical University, Shinjuku 6 1 1, Shinjuku ku Tokyo, Japan
    Cytokine 22:50-3. 2003
    ..of exogenously administered recombinant murine interleukin (IL)-10 on the development of experimental autoimmune orchitis (EAO) in C3H/He mice...
  53. ncbi Clinical features of testicular torsion and epididymo-orchitis in infants younger than 3 months
    Ming Chou Chiang
    Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Chang Gung Children s Hospital, Taiwan
    J Pediatr Surg 42:1574-7. 2007
    Testicular torsion (TT) and orchitis/epididymo-orchitis (EO) are confusing and difficult for physicians to diagnose in infants younger than 3 months...
  54. ncbi Late occurrence of bilateral tuberculous-like epididymo-orchitis after intravesical bacille Calmette-Guérin therapy for superficial bladder carcinoma
    C Falkensammer
    Department of Urology, University of Innsbruck, Innsbruck, Austria
    Urology 65:175. 2005
    We report a case of bilateral tuberculous-like epididymo-orchitis occurring 3 years after intravesical bacille Calmette-Guérin instillation therapy in an 83-year-old patient with proven superficial bladder carcinoma...
  55. ncbi Post-transplant epididymitis and orchitis following Listeria monocytogenes septicaemia
    C von Schnakenburg
    Department of Paediatric Nephrology, Kinderklinik der Medizinischen Hochschule, Hannover, Germany
    Pediatr Transplant 4:156-8. 2000
    We report the occurrence of epididymitis and orchitis 1 week after the onset of Listeriosis in an 11-month-old boy receiving an orthotopic liver transplantation for biliary atresia...
  56. ncbi Mechanisms of autoimmune disease in the testis and ovary
    K S Tung
    Department of Pathology, University of Virginia, Charlottesville 22908, USA
    Hum Reprod Update 1:35-50. 1995
    ..The inflammatory CD4 (Th1) T cell mechanism has been established to be a critical pathway for autoimmune orchitis and autoimmune oophoritis; tumour necrosis factor has been shown to be required for amplification of the ..
  57. ncbi Mumps orchitis in the non-immune postpubertal male: a resurgent threat to male fertility?
    Joe Philip
    Department of Urology, Royal Liverpool and Broadgreen University Hospital NHS Trust, Liverpool, UK
    BJU Int 97:138-41. 2006
    To report clinical findings associated with an increased incidence of mumps orchitis in Liverpool, UK, as in the last 2 years there has been a four-fold increase in the number of notified viral mumps cases in the UK.
  58. ncbi Experimental allergic orchitis in mice. VI. Recombinations within the H-2S/H-2D interval define the map position of the H-2-associated locus controlling disease susceptibility
    C Teuscher
    Division of Reproductive Biology, University of Pennsylvania School of Medicine, Philadelphia
    Immunogenetics 32:337-44. 1990
    Susceptibility to autoimmune orchitis is associated with an immune response (Ir) gene (now designated Orch-1) which was preliminarily shown to reside at or near the H-2D subregion of the major histocompatibility complex in the mouse (H-2)...
  59. ncbi Suppurative epididymo-orchitis and chronic prostatitis caused by Burkholderia pseudomallei: a case report and review
    Magalie Demar
    Parasitology Mycology Unit, Cayenne Hospital University of West Indies and French Guiana University
    J Travel Med 12:108-12. 2005
  60. ncbi Adeno-associated virus-mediated human IL-10 gene transfer suppresses the development of experimental autoimmune orchitis
    M Watanabe
    Department of Urology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Gene Ther 12:1126-32. 2005
    Testicular germ cell-induced autoimmune orchitis is characterized by inflammatory cell infiltration followed by disturbance of spermatogenesis...
  61. ncbi Xanthogranulomatous funiculitis and orchiepididymitis: report of 2 cases with immunohistochemical study and literature review
    Manuel Nistal
    Department of Pathology, La Paz Hospital, Spain
    Arch Pathol Lab Med 128:911-4. 2004
    ..Clinically, our patients presented with spermatic cord enlargement (case 1) and chronic orchitis that did not respond to treatment with antibiotics (case 2)...
  62. ncbi Preoperative diagnosis of bilateral tuberculous epididymo-orchitis following intravesical Bacillus Calmette-Guerin therapy for superficial bladder carcinoma
    Malai Muttarak
    Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
    Australas Radiol 46:183-5. 2002
    We report a case of bilateral tuberculous epididymo-orchitis following intravesical Bacillus Calmette-Guerin (BCG) therapy for superficial bladder carcinoma in which the diagnosis was made by ultrasonography prior to surgery...
  63. ncbi Diagnosis of isolated tuberculous orchitis by fine-needle aspiration cytology
    Rajendra Singh Garbyal
    Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    Diagn Cytopathol 34:698-700. 2006
    An isolated tuberculous Orchitis without epididymal involvement is rare. This case report describes an extra pulmonary tuberculosis with exclusively testicular presentation...
  64. ncbi Defects in the regulatory clearance mechanisms favor the breakdown of self-tolerance during spontaneous autoimmune orchitis
    R Marc Pelletier
    Departement de pathologie et biologie cellulaire, Universite de Montreal, QC, Canada
    Am J Physiol Regul Integr Comp Physiol 296:R743-62. 2009
    We identified aberrations leading to spontaneous autoimmune orchitis (AIO) in mink, a seasonal breeder and natural model for autoimmunity...
  65. ncbi Clinical findings, diagnostic approach, and outcome of Brucella melitensis epididymo-orchitis
    Juan D Colmenero
    Infectious Diseases Service, Carlos Haya University Hospital, 29010 Malaga, Spain
    Diagn Microbiol Infect Dis 57:367-72. 2007
    We have studied 912 patients with brucellosis. Of these, 631 (69.2%) were male and 48 had epididymo-orchitis, giving an incidence of epididymo-orchitis of 7.6%. The duration of symptoms before diagnosis was 52.5 +/- 70 days...
  66. ncbi Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism
    Vanessa Clifford
    Infectious Diseases Unit, Department of General Medicine and Murdoch Childrens Research Institute, Royal Children s Hospital Melbourne, Parkville, Victoria 3052, Australia
    Vaccine 28:2671-3. 2010
    We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination...
  67. ncbi Immunoprivileged sites: the testis
    Monika Fijak
    Department of Anatomy and Cell Biology, Justus Liebig University of Giessen, Giessen, Germany
    Methods Mol Biol 677:459-70. 2011
    ....
  68. ncbi Tuberculous epididymo-orchitis and prostatitis: a case report
    M Ludwig
    Urological Practice A von Keitz, M Schwickardi and M Ludwig, Marburg, Germany
    Andrologia 40:81-3. 2008
    ..The treatment of choice is primarily medical, consisting of a combination of three or four anti-TB drugs, sometimes combined with surgery...
  69. ncbi Malignant tumor of testis imitating epididymo-orchitis
    H W Kao
    Department of Radiology, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
    Arch Androl 51:407-11. 2005
    ..All the findings including color duplex ultrasonography (US) and scintigraphy were considered as right epididymo-orchitis. Unfortunately, the patient presented with metastatic lymphadenopathy of the neck from mixed germ cell tumor of ..
  70. ncbi Tumour necrosis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis
    M S Theas
    Instituto de Investigaciones en Reproducción, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, Piso 10, C1121 ABG Buenos Aires, Argentina
    Hum Reprod 23:1865-72. 2008
    Experimental autoimmune orchitis (EAO) is a model of chronic inflammation and infertility useful for studying testicular immune and germ cell (GC) interactions...
  71. ncbi Xanthogranulomatous orchitis in an adult Nigerian
    Abdulkadir A Salako
    Department of Surgery, Obafemi Awolowo University, Ile Ife, Nigeria
    Int J Urol 13:186-8. 2006
    Xanthogranulomatous orchitis (XGO) is a rare benign disease of the testis which has not been previously documented in tropical Africa. We report a case of a 24-year-old Nigerian man who presented with a painless left hemiscrotal swelling...
  72. ncbi Meconium periorchitis--a rare cause of a paratesticular mass
    Helen J Williams
    Department of Radiology, Royal Liverpool Children s Hospital, Alder Hey, Eaton Road, Liverpool, L12 2AP, UK
    Pediatr Radiol 34:421-3. 2004
    ..Histology confirmed the unexpected diagnosis of meconium periorchitis, a rare, benign condition resulting from intrauterine bowel perforation...
  73. ncbi Xanthogranulomatous orchitis
    Ronald L Yap
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Urology 63:176-7. 2004
    ..Only two prior cases of xanthogranulomatous orchitis have been reported...
  74. ncbi Involvement of tumor necrosis factor-alpha in the pathogenesis of autoimmune orchitis in rats
    Maria O Suescun
    Instituto Multidisciplinario de Biologia Celular, CONICET, La Plata, Argentina
    Biol Reprod 68:2114-21. 2003
    We studied the testicular macrophages of rats with experimental autoimmune orchitis (EAO) and analyzed whether the tumor necrosis factor-alpha (TNFalpha) is involved in germ cell apoptosis and in Leydig cell steroidogenesis...
  75. ncbi The direct medical cost of epididymitis and orchitis: evidence from a study of insurance claims
    Thomas L Gift
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Sex Transm Dis 33:S84-8. 2006
    Epididymitis and orchitis (EO) are the primary sequelae of acute chlamydia and gonorrhea in men. Existing estimates of the cost per episode of epididymitis are over 10 years old or are based on limited data.
  76. ncbi Comparison of tuberculous and pyogenic epididymal abscesses: clinical, gray-scale sonographic, and color Doppler sonographic features
    D M Yang
    Department of Radiology, Gachon Medical College, Gil Medical Center, 1198, Guwol-Dong, Namdong-gu, Inchon, 405-760, South Korea
    AJR Am J Roentgenol 177:1131-5. 2001
    ..The presence of long-term scrotal swelling without tenderness and a lower degree of blood flow in the peripheral portion of a large abscess are suggestive of tuberculous epididymal abscess...
  77. ncbi Brucella epididymo-orchitis: a consideration in endemic area
    Jaffar A Al-Tawfiq
    Internal Medicine Services Division, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia
    Int Braz J Urol 32:313-5. 2006
    Brucellosis is a zoonotic disease caused by Brucella sp. and may affect many parts of the body. Brucella epididymo-orchitis had been reported in up to 20% of patients with brucellosis...
  78. ncbi Acute scrotum in Nigeria: an 18-year review
    N H Mbibu
    Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Nigeria
    Trop Doct 34:34-6. 2004
    ..Twelve per cent of cases of suspected torsion were found to have epididymo-orchitis, at exploration...
  79. ncbi Tubercular scrotal disease
    Kim R Geisinger
    Acta Cytol 50:241-2. 2006
  80. ncbi Are we missing mumps epididymo-orchitis?
    C Emerson
    Royal Victoria Hospital, Belfast, Northern Ireland
    Int J STD AIDS 18:341-2. 2007
    Mumps epididymo-orchitis has not been recorded as a cause of testicular symptoms without systemic features (including parotitis)...
  81. ncbi Epididymo-orchitis and testicular abscess caused by Salmonella enteritidis in immunocompromised patients in Kuwait
    Khalid Al-Obeid
    Department of Microbiology, Mubarak Al Kabeer Teaching Hospital, Kuwait
    Med Princ Pract 15:305-8. 2006
    To report relatively uncommon presentations of epididymo-orchitis and testicular abscess caused by Salmonella spp. in 2 immunocompromised patients.
  82. ncbi Endemic brucellar epididymo-orchitis: a 10-year experience
    Athanasios G Papatsoris
    Department of Urology, St Andrews Patras Regional Hospital, Greece
    Int J Infect Dis 6:309-13. 2002
    ..and laboratory features, treatment and outcome of patients suffering from Brucella melitensis-induced epididymo-orchitis, in comparison with cases of nonspecific epididymo-orchitis...
  83. ncbi [Ultrasound of the scrotum]
    G Stuckmann
    Institut fur Radiologie, Kantonsspital Winterthur
    Praxis (Bern 1994) 95:709-20. 2006
    ..In cases of acute scrotum or of vascular and inflammatory lesions, Doppler ultrasound is mandatory. This article gives a systematical survey of the most frequent scrotal lesions and their appearance in ultrasound...
  84. ncbi Testicular torsion revisited
    John R Mernagh
    Department of Radiology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Curr Probl Diagn Radiol 33:60-73. 2004
    ..Other abnormalities that can be potentially confused with testicular torsion, including epididymitis and orchitis, will be shown...
  85. ncbi [Pseudoneoplastic form of Chlamydia trachomatis epididymo-orchitis: a case report]
    Emmanuel Kessler
    Service de Chirurgie Urologique et Andrologie, CHRU de Limoges, France
    Prog Urol 13:1392-3. 2003
    Pseudoneoplastic Chlamydia trachomatis epididymo-orchitis is a rare clinical entity. The differential diagnosis with malignant tumour of the testis remains difficult and surgical exploration with orchidectomy is often difficult to avoid...
  86. ncbi Electro-orchidogram: a non-invasive diagnostic tool in testicular pathologies
    Ahmed Shafik
    Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, Egypt
    Med Sci Monit 12:MT51-5. 2006
    ..We investigated the hypothesis that the transcutaneous electro-orchidogram (EOG) can act as a diagnostic tool in testicular pathological conditions...
  87. ncbi Epididymo-orchitis complicating Streptococcus pyogenes throat infection
    Sebastiaan J van Hal
    Department of Infectious Diseases, Prince of Wales Hospital, Barker Street, Randwick, NSW 2031
    Med J Aust 178:89. 2003
  88. ncbi Effect of experimentally induced Escherichia coli epididymo-orchitis and ciprofloxacin treatment on rat spermatogenesis
    Aslan Demir
    Department of Urology, Marmara University School of Medicine, Tophanelioglu Cd 13 15, Altunizade 34662, Istanbul, Turkey
    Int J Urol 14:268-72. 2007
    We investigated the effects of epididymo-orchitis and ciprofloxacin on rat testicular histology and spermatogenesis. The control group underwent left orchiectomy. The second group received oral ciprofloxacin (150 mg/kg/day) for 10 days...
  89. pmc Pseudoneoplastic lesions of the testis and paratesticular structures
    F Algaba
    Pathology Section, Fundacio Puigvert, Barcelona, Spain
    Virchows Arch 451:987-97. 2007
    ..These lesions can be classified as macroscopic or microscopic mimickers of neoplasia...
  90. ncbi [Isolation of Brucella melitensis from ejaculate culture of a brucellosis patient with epididymoorchitis]
    Ebru Emel Sozen
    Karadeniz Teknik Universitesi Tip Fakültesi, Enfeksiyon Hastaliklari ve Klinik Mikrobiyoloji Anabilim Dali, Trabzon
    Mikrobiyol Bul 41:465-8. 2007
    ....
  91. ncbi Unilateral orchitis and epididymitis caused by Salmonella enterica subspecies diarizonae infection in a ram
    Ma del Carmen Ferreras
    Dpto Patologia Animal Medicina Animal Anatomia Patológica, Facultad de Veterinaria, Universidad de Leon, Campus de Vegazana, S N, 24071 Leon, Spain
    J Vet Diagn Invest 19:194-7. 2007
    A case of unilateral suppurative epididymo-orchitis associated with Salmonella enterica subsp. diarizonae serovar 61:k:1,5,(7) infection is described in a 2-year-old ram...
  92. ncbi Case report. Tuberculous epididymo-orchitis: MRI findings
    A C Tsili
    Department of Clinical Radiology, University Hospital of Ioannina, 45500 Ioannina, Greece
    Br J Radiol 81:e166-9. 2008
    ..Urine cultures obtained from a percutaneous left nephrostomy were positive for tuberculous bacilli, and the patient was placed on anti-tuberculous treatment...
  93. ncbi Scrotal involvement in childhood Henoch-Schönlein purpura
    Tae Sun Ha
    Department of Pediatrics, College of Medicine, Chungbuk National University Hospital, Cheongju, Korea
    Acta Paediatr 96:552-5. 2007
    ..Henoch-Schönlein purpura (HSP) is a common childhood systemic vasculitis involving the skin, gastrointestinal tract, joint, kidneys and even scrotum...
  94. ncbi Clinical presentation of acute scrotum in young males
    Chia Chu Liu
    Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 23:281-6. 2007
    ..torsion (TT), eight patients with torsion of the testicular appendage (TTA), and 38 patients with epididymo-orchitis (EO). The mean ages of the TT group (14.0 +/- 5.7 years) and EO group (16.6 +/- 7...
  95. ncbi Brucella abortus epididymo-orchitis relapsing in the opposite testis 3 months after antibiotic therapy and development of aspermia
    Esragul Akinci
    Int J Infect Dis 7:290-1. 2003
  96. ncbi [Scrotal ultrasonography. Part I: common non-cancerous pathologies]
    C Roy
    Service de Radiologie B, Chir A, Hopitaux Universitaires de Strasbourg, Hopital Civil, 1 Place de l Hopital, BP 426, 67091 Strasbourg
    J Radiol 84:581-95. 2003
    ..When a tumoral process is suspected, surgery is required to confirm the diagnosis and provide histology. The role of MR remains under evaluation...
  97. ncbi [Testicular microlithiasis and testicular cancer]
    Manuel Angel Ortiz Gorraiz
    Servicio de Urologia, Hospital Universitario Virgen de las Nieves, Granada, Espana
    Arch Esp Urol 56:521-4. 2003
    ..The etiopathogenesis, incidence and attitude are discussed...
  98. ncbi Role of fine needle aspiration cytology in nonneoplastic testicular and scrotal lesions and male infertility
    Um Handa
    Department of Pathology and Surgery, Government Medical College and Hospital, Chandigarh, India
    Acta Cytol 50:513-7. 2006
    ..To study the role of fine needle aspiration (FNA) in male infertility and in nonneoplastic lesions of the testis and scrotum...
  99. ncbi Measles, mumps and rubella -- the urologist's perspective
    R Singh
    North Hampshire NHS Trust, Urology, Hampshire, UK
    Int J Clin Pract 60:335-9. 2006
    ..The article reviews the pathophysiology, clinical symptoms, diagnosis, and long-term sequelae of this increasingly prevalent condition and provides a reference for all practising urologists treating this disease...
  100. ncbi [Tuberculous orchiepididymitis and CNS complication]
    B Miletic
    Klinik fur Innere Medizin, Klinisches Krankenhaus Rijeka, Kroatien
    Aktuelle Urol 37:67-8. 2006
    ..Hydrocephalus as a complication of tuberculous orchiepididymitis is extremely rare. In this reported case, hydrocephalus was the consequence of a disseminated tuberculous process...
  101. ncbi Addisonian crisis and tuberculous epididymo-orchitis
    Yin Chian Kon
    Department of Medicine, University of Chicago, Illinois 60637, USA
    Endocr Pract 8:365-9. 2002
    To describe a case of acute primary adrenal insufficiency in which tuberculosis was subsequently detected as the etiologic factor when the patient presented with tuberculous epididymo-orchitis.

Research Grants15

  1. Advanced Nitric Oxide Release Bactericidal Urinary Catheters
    Mark E Meyerhoff; Fiscal Year: 2013
    ..such as cystitis, pyelonephritis, gram-negative bacteremia, prostatitis, epididymitis, urosepsis, septicemia, orchitis, endocarditis, vertebral osteomyelitis, septic arthritis, endophthalmitis, and meningitis n all patients...
  2. PURIFIED TESTIS ANTIGENS AND TESTICULAR AUTOIMMUNITY
    Kenneth Tung; Fiscal Year: 1991
    Murine experimental allergic orchitis (EAO) has been induced with mouse testis homogenate (TH) or rat Sertoli cell plasma membrane (RSCPM), using Bordetella pertussis extract (BPE) as adjuvant...
  3. REGULATION OF E-SELECTIN DURING ACUTE INFLAMMATION
    Kevin Billups; Fiscal Year: 1999
    ..Examples of specific disorders include: pyelonephritis, cystitis, epididymitis, orchitis, and prostatitis...
  4. REGULATION OF TESTICULAR BLOOD FLOW
    Claude Desjardins; Fiscal Year: 1993
    ..reproductive health because it provides a framework for investigating the unknown etiology of testicular vascular disorders (varicocele, orchitis, and cryptorchidism), the most prominent source of testicular dysfunction and infertility.
  5. IMMUNOREGULATORY LOCI IN ORGAN SPECIFIC AUTOIMMUNITY
    Cory Teuscher; Fiscal Year: 2001
    ..For example, two less popular models, experimental allergic orchitis (EAO) and autoimmune ovarian dysgenesis (AOD), are at the forefront of characterizing the genetic architecture of ..
  6. BASIC AND CLINICAL RHEUMATOLOGY
    JOEL TAUROG; Fiscal Year: 2005
    ..Simmons Arthritis Research Center, University of Texas Southwestern Medical Center. ..
  7. Autoimmunity and Pathogenesis of Glomerulonephritis
    Harini Bagavant; Fiscal Year: 2010
    ..These studies will provide insights into pathogenesis of lupus nephritis and identify checkpoints for intervention in patients. ..
  8. HLA-B27 and Experimental Spondyloarthropathy
    JOEL TAUROG; Fiscal Year: 2009
    ..Overall, the project should contribute substantially to resolving several important issues about the role of HLA-B27 and innate immunity in chronic inflammatory disease. ..
  9. Regulatory T cells in Systemic Lupus Erythematosus
    Harini Bagavant; Fiscal Year: 2007
    ..This award will help to overcome the lag period in my career induced by my leave of absence and return to a new field of study, and will facilitate my aim of becoming an independent scientist. ..
  10. Role of T Cells in Experimental Spondyloarthropathy
    JOEL TAUROG; Fiscal Year: 2002
    ..These experiments will examine directly the effect of Tap2a on the B27 peptide repertoire and on disease manifestations. ..
  11. GLYCOCONJUGATE-INDUCED TOLERANCE IN NATURAL KILLER CELLS
    Gary Clark; Fiscal Year: 2002
    ..The primary goal of this study is to carry out experiments complementing preliminary studies in support of this glycoconjugate-based model. ..
  12. Potential Role of Glycosylation in AIDS Pathogenesis
    Gary Clark; Fiscal Year: 2005
    ..These preliminary studies will be crucial for determining if HIV-1 is employing its carbohydrate sequences as functional groups to mediate immune suppression. ..
  13. Autoimmune Oophoritis: Consequences of Gamete Vaccines
    Kenneth Tung; Fiscal Year: 2006
    ..Specifically, we will determine the immunogenetic regulation of the immune response to CP2, and the influence of the B cell epitope specificity of the ZP Ab on the induction of progenic AOD. ..
  14. Sertoli Cell Mediated Engulfment of Apoptotic Germ Cells
    Kodi S Ravichandran; Fiscal Year: 2010
    ..abstract_text> ..