chondroma

Summary

Summary: A benign neoplasm derived from mesodermal cells that form cartilage. It may remain within the substance of a cartilage or bone (true chondroma or enchondroma) or may develop on the surface of a cartilage (ecchondroma or ecchondrosis). (Dorland, 27th ed; Stedman, 25th ed)

Top Publications

  1. ncbi Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Oncol Rep 18:9-15. 2007
  2. pmc Loss of β-catenin induces multifocal periosteal chondroma-like masses in mice
    Leslie Cantley
    Translational Research Program in Pediatric Orthopaedics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Pathol 182:917-27. 2013
  3. ncbi [Septal nasal chondroma--a case report]
    Wojciech Scierski
    Katedra i Oddział Kliniczny Laryngologii w Zabrzu Slaskiego UM w Katowicach
    Otolaryngol Pol 61:1021-3. 2007
  4. ncbi Laryngeal chondroma presenting as a laryngopyocele
    Irfan Papila
    Department of Otorhinolaryngology, Cerrahpasa Medical Faculty of Istanbul University, Turkey
    Eur Arch Otorhinolaryngol 262:473-6. 2005
  5. ncbi Periosteal chondroma: MR characteristics
    K Woertler
    Department of Radiology, Technische Universitaet Muenchen, Germany
    J Comput Assist Tomogr 25:425-30. 2001
  6. doi Heterogeneity of angiogenesis and blood vessel maturation in cartilage tumors
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:339-45. 2009
  7. pmc The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications
    C A Stratakis
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, NICHD, NIH, Building 10, CRC, Room 1 3330, 10 Center Dr, MSC1103, Bethesda, MD 20892, USA
    J Intern Med 266:43-52. 2009
  8. pmc Para-articular chondroma and osteochondroma of the infrapatellar fat pad: a report of three cases
    H Sakai
    Department of Orthopaedic Surgery, Dokkyo University School of Medicine, Tochigi, Japan
    Int Orthop 23:114-7. 1999
  9. ncbi Extraskeletal chondroma of the foot
    Panayiotis J Papagelopoulos
    First Department of Orthopaedics, Athens University Medical School, 4 Christovassili Street, Neo Psychikon, 15451 Athens, Greece
    Joint Bone Spine 74:285-8. 2007
  10. ncbi Cyclooxygenase-2 expression in chondrosarcoma
    Karen M Sutton
    Orthopedic Biological Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Oncology 66:275-80. 2004

Research Grants

Detail Information

Publications236 found, 100 shown here

  1. ncbi Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Oncol Rep 18:9-15. 2007
    ..by metachronous or synchronous occurrence of epithelioid gastrointestinal stromal tumours (GISTs), pulmonary chondroma and extra-adrenal paraganglioma...
  2. pmc Loss of β-catenin induces multifocal periosteal chondroma-like masses in mice
    Leslie Cantley
    Translational Research Program in Pediatric Orthopaedics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Pathol 182:917-27. 2013
    ..studying the role of β-catenin in cartilage development, we found that its conditional deletion induces ectopic chondroma-like cartilage formation in mice...
  3. ncbi [Septal nasal chondroma--a case report]
    Wojciech Scierski
    Katedra i Oddział Kliniczny Laryngologii w Zabrzu Slaskiego UM w Katowicach
    Otolaryngol Pol 61:1021-3. 2007
    Cartilaginous tumors of the head and neck are rare. The most frequent site is larynx and spheno-ethmoidal area. Chondroma of the nasal septum is very rare...
  4. ncbi Laryngeal chondroma presenting as a laryngopyocele
    Irfan Papila
    Department of Otorhinolaryngology, Cerrahpasa Medical Faculty of Istanbul University, Turkey
    Eur Arch Otorhinolaryngol 262:473-6. 2005
    ..We present a patient with laryngopyocele that arose because of a laryngeal chondroma.
  5. ncbi Periosteal chondroma: MR characteristics
    K Woertler
    Department of Radiology, Technische Universitaet Muenchen, Germany
    J Comput Assist Tomogr 25:425-30. 2001
    The purpose of this study was to describe the MR characteristics of periosteal chondroma.
  6. doi Heterogeneity of angiogenesis and blood vessel maturation in cartilage tumors
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:339-45. 2009
    ..Altogether, cartilage tumors exhibit a heterogeneous but predominantly mature angiogenic phenotype with differential proliferative activity...
  7. pmc The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications
    C A Stratakis
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, NICHD, NIH, Building 10, CRC, Room 1 3330, 10 Center Dr, MSC1103, Bethesda, MD 20892, USA
    J Intern Med 266:43-52. 2009
    ....
  8. pmc Para-articular chondroma and osteochondroma of the infrapatellar fat pad: a report of three cases
    H Sakai
    Department of Orthopaedic Surgery, Dokkyo University School of Medicine, Tochigi, Japan
    Int Orthop 23:114-7. 1999
    We report three cases of para-articular chondroma and osteochondroma in the region of infrapatellar fat pad. All three lesions were resected and examined histologically...
  9. ncbi Extraskeletal chondroma of the foot
    Panayiotis J Papagelopoulos
    First Department of Orthopaedics, Athens University Medical School, 4 Christovassili Street, Neo Psychikon, 15451 Athens, Greece
    Joint Bone Spine 74:285-8. 2007
    ..The authors present herein the case of a 74-year-old man with a painful mass at the dorsomedial aspect of the left foot. At 34 months after surgery the patient is disease-free with no evidence of recurrence...
  10. ncbi Cyclooxygenase-2 expression in chondrosarcoma
    Karen M Sutton
    Orthopedic Biological Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Oncology 66:275-80. 2004
    ..There is now a mounting body of information that strongly implies that COX-2 inhibitors may be of some value in the management of patients with carcinomas, and most recently several similar reports have appeared relating to sarcomas...
  11. ncbi Comparative genomic hybridization in cartilaginous tumors
    Toshifumi Ozaki
    Department of Orthopaedics, Westfaelische Wilhelms University, Muenster, Germany
    Anticancer Res 24:1721-5. 2004
    ..Therefore, although the number of aberrations between benign and malignant cartilaginous tumors appears to be similar, these two entities may be differentiated by determining which chromosomes are affected...
  12. ncbi Differential expression of VEGF-A and angiopoietins in cartilage tumors and regulation by interleukin-1beta
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Cancer 106:2028-38. 2006
    ..As interleukin (IL)-1beta has been found to be an indispensable factor in angiogenic signaling, we further analyzed the effect of IL-1beta on the expression of VEGF-A, Ang-1, and Ang-2 using a previously established cell culture model...
  13. doi Chondromyxoid fibroma
    Adam M Budny
    Nason Hospital, Roaring Spring, PA, USA
    J Foot Ankle Surg 47:153-9. 2008
    ..Early detection and complete surgical resection are valuable in preventing recurrence in the affected bone. ACFAS Level of Clinical Evidence: 4...
  14. doi Diffuse mineralization of forearm extraskeletal chondroma
    Thomas Le Corroller
    Department of Radiology, La Timone Hospital, Marseille, France
    Joint Bone Spine 75:479-81. 2008
    We report on the clinical, histologic, and radiologic features - including CT and MRI - of extraskeletal chondroma in a rare case of diffuse calcification of the chondroid matrix...
  15. doi Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 94:3656-62. 2009
    Two young women, each with paraganglioma and gastric stromal tumor, were encountered in the middle 1970s. One also had an adrenal cortical adenoma and the other pulmonary chondroma.
  16. ncbi [Diagnosis and differential diagnosis of extraskeletal, para-articular chondroma of the knee]
    B Schmidt-Rohlfing
    Orthopadische Klinik, Universitätsklinikum der RWTH Aachen, Germany
    Z Orthop Ihre Grenzgeb 140:544-7. 2002
    ..Extraskeletal chondromas in the region of the knee joint are very rare tumors which may cause diagnostic problems and have concomitant therapeutic consequences...
  17. ncbi Intracortical chondroma simulating osteoid osteoma treated by radiofrequency
    R Richard Ramnath
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Skeletal Radiol 31:597-602. 2002
    ..Pathologic evaluation of the specimens revealed features consistent with benign intracortical chondroma. In one case radiofrequency treatment appears to have cured the tumor...
  18. ncbi Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review
    Hung Ta Hondar Wu
    Department of Radiology, Veterans General Hospital Taipei, National Yang Ming University, Shih Pai Road 201, Taipei 122, Taiwan, ROC
    Clin Imaging 30:32-6. 2006
    ..findings (X-ray and MRI) and patterns of calcification of five patients with pathologically proven soft-tissue chondroma were correlated with histopathology. The size ranged from 0.5 to 3 cm...
  19. ncbi Childhood soft tissue chondroma. Two cases report
    Mahmoud Smida
    Department of Pediatric Orhtopedic Surgery, Children Hospital Tunis, Tunisia
    Tunis Med 89:379-82. 2011
    Soft tissue chondroma is a rare benign tumour, which is generally seen in adult. It consists of islands of heterotopic cartilaginous tissue and most localised on the hands and the feet...
  20. ncbi Current limitations to the histopathological diagnosis of some frequently encountered bone tumours
    Christine Galant
    Department of Pathology, Cliniques Universitaires Saint Luc, Bruxelles, Belgium
    Acta Orthop Belg 74:1-6. 2008
    ..However there are situations in which a discrepancy exists between histology and imaging studies and where histology alone cannot be decisive. This paper reviews such situations...
  21. ncbi A peculiar site of chondroma: the epiglottis
    Shih Wei Yang
    Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan
    Acta Otolaryngol 125:906-9. 2005
    b>Chondroma of the laryngeal cartilage is an uncommon benign cartilaginous neoplasm. The commonest location is the posterior lamina of the cricoid cartilage, followed by the thyroid cartilage...
  22. ncbi Soft-tissue chondroma of the masticatory space
    G De Riu
    Department of Maxillofacial Surgery, University of Sassari, Sassari, Italy
    Int J Oral Maxillofac Surg 36:174-6. 2007
    Soft-tissue chondroma is an infrequent, benign, cartilaginous tumour that is uncommon in the head and neck region. Single-location chondromas rarely evolve into malignant neoplasms...
  23. ncbi Extraskeletal ossifying chondroma in Hoffa's fat pad: an unusual cause of anterior knee pain
    V K Singh
    Department of Trauma and Orthopaedics, Luton and Dunstable Hospital, Luton, LU4 0DZ, UK
    Singapore Med J 50:e189-92. 2009
    ..We report a giant extraskeletal ossifying chondroma in a 55-year-old man, presented as chronic knee pain and successfully treated by excision...
  24. ncbi A case of chondroma of the tongue
    H Sera
    Department of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka 814 0193, Japan
    Int J Oral Maxillofac Surg 34:99-100. 2005
    b>Chondroma of the tongue represents a very rare benign tumor at this site, with very few reports of pure chondroma (no components of adipose, fibrous or bony tissue) existing...
  25. ncbi Convexity dural chondroma: a case report and review of the literature
    Efkan Colpan
    Department of Neurosurgery, Ankara University of Medical School, Ankara, Turkey
    J Clin Neurosci 10:106-8. 2003
    ..In rare instances, these tumours originate from the dura mater of the convexity. We report a rare case of a chondroma arising from the convexity dura mater. The origin of this tumour is analysed and the literature reviewed.
  26. doi Extraskeletal chondroma of the masseter muscle: a case report with review of the literature
    J Falleti
    Department of Biomorphological and Functional Science, Section of Anatomic Pathology, Federico II University, Via S Pansini 5, Naples, Italy
    Int J Oral Maxillofac Surg 38:895-9. 2009
    The authors report a case of soft tissue chondroma of the masseter muscle in a 49-year-old man. The tumour was entirely composed of lobules of hyaline cartilage. The literature on head and neck soft tissue chondroma is also reviewed...
  27. ncbi Chondrolipoma of the popliteal fossa and Japanese reports
    Hisashi Ohtsuka
    Surgical Division C, Ehime University Hospital, Ehime, Japan
    J Dermatol 33:202-6. 2006
    ..The presented tumor was an early one because of the shortest duration and the smallest size in Japan. Recent criteria for a benign mesenchymoma including a chondrolipoma were also described...
  28. ncbi Intracapsular and para-articular chondroma adjacent to large joints: report of three cases and review of the literature
    C Gonzalez-Lois
    Department of Pathology, University Hospital Doce de Octubre, Carretera de Andalucía Km 5400, Madrid 28041, Spain
    Skeletal Radiol 30:672-6. 2001
    Para-articular chondroma is a rare tumor that has been reported in only 30 cases adjacent to large joints in the Anglo-Saxon literature...
  29. ncbi Chondroma and chondrosarcoma of the larynx
    Robert J Baatenburg de Jong
    Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Holland
    Curr Opin Otolaryngol Head Neck Surg 12:98-105. 2004
    The purpose of this review is to give a detailed description of chondroma and chondrosarcoma of the larynx and to put into perspective new findings from recent literature.
  30. ncbi Chondroma/Chondrosarcoma of the spine
    Gregory S McLoughlin
    Division of Neurosurgery, University of Saskatchewan, University Hospital, 103 Hospital Drive, Saskatoon, Saskatchewan, S7N 0W8, Canada
    Neurosurg Clin N Am 19:57-63. 2008
    ..These neoplasms exist on opposite ends of the pathologic spectrum, ranging from the benign chondroma to the malignant, high-grade chondrosarcoma...
  31. ncbi Immunohistochemical study of chondrolipoma: possible importance of transforming growth factor (TGF)-betas, latent TGF-beta binding protein-1 (LTBP-1), and bone morphogenetic protein (BMP) for chondrogenesis in lipoma
    Mineo Nakano
    Division of Plastic and Reconstructive Surgery, Organized Center of Clinical Medicine, International University of Health and Welfare, Tochigi, Japan
    J Dermatol 30:189-95. 2003
    ..These findings suggest that the pattern of expression of TGF-betas, LTBP-1, and BMP may be important in the pathogenesis of chondrolipoma...
  32. doi Microsurgical treatment of intracranial chondroma
    Yu Xin
    Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Tiantan Xili 6, Chongwen District, Beijing 100050, China
    J Clin Neurosci 18:1064-71. 2011
    ..Thus, we aimed to describe a large series of patients with intracranial chondroma and to analyze and discuss the clinical features and microsurgical treatment of these patients...
  33. ncbi Large chondroma of the dural convexity in a patient with Noonan's syndrome. Case report and review of the literature
    P D Delgado-López
    Servicios de Neurocirugía, Hospital General Yague, Burgos
    Neurocirugia (Astur) 18:241-6. 2007
    ..We describe the case of a young male diagnosed of Noonan's syndrome that underwent resection of a large intracranial chondroma arising from the dural convexity. To our best knowledge this is the first report of such association.
  34. ncbi Bizarre parosteal osteochondromatous proliferation and periosteal chondroma: a comparative report and review of the literature
    James H Flint
    Uniformed Services University of Health Sciences, Bethesda, MD, USA
    J Hand Surg Am 32:893-8. 2007
    Bizarre parosteal osteochondromatous proliferation and periosteal chondroma are rare, benign, bony lesions that may present in the hand...
  35. ncbi Intestinal chondrolipoma: uncommon cause of bowel obstruction
    Hye Ra Jung
    Department of Pathology, Keimyung University Dongsan Medical Center, Daegu 700 712, South Korea
    J Pediatr Surg 42:E21-3. 2007
    ..To the best of our knowledge, this seems to be the first report of chondrolipoma arising from the small bowel in English language literatures...
  36. ncbi Chondrolipoma of the oropharynx
    Y P Halaas
    Department of Otolaryngology-Head and Neck Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, USA
    Ear Nose Throat J 80:146-7. 2001
    ..The lesion was excised, and histopathology determined that it was a chondrolipoma. We believe that this is the first report of a chondrolipoma at this anatomic site...
  37. ncbi Extraskeletal chondroma of parotid gland
    M B Aslam
    Histopathology 48:465-7. 2006
  38. doi Giant cystic intracranial chondroma of the falx with review of literature
    Amita Patel
    Department of Histopathology, William Harvey Hospital, Ashford, Kent, UK
    Neuropathology 29:315-7. 2009
    ..Our case illustrates the benignity of the intracranial chondroma and to our knowledge, is one of the longest surviving and largest cases found after incomplete removal.
  39. ncbi Chondroblastoma-like chondroma of soft tissue: an underrecognized variant and its differential diagnosis
    J M Cates
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School Boston, Massachusetts, USA
    Am J Surg Pathol 25:661-6. 2001
    ..The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification...
  40. ncbi Chondroma of the cheek: A case report
    K Onodera
    Division of Oral Pathology, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Int J Oral Maxillofac Surg 34:924-6. 2005
    An extremely rare case of soft tissue chondroma occurring in the right cheek of a 47-year-old woman is reported. The localized nodular tumor was encapsulated and composed of hyalinized cartilage with fine calcifications...
  41. ncbi Giant chondroma arising from the dura mater of the convexity. Case report and review of the literature
    M Nakayama
    Department of Neurosurgery, Faculty of Medicine, Kagoshima University, Japan
    J Neurosurg 94:331-4. 2001
    ..The authors present a case of intracranial giant chondroma originating from the dura mater of the convexity. Neuroimaging and surgical findings are described...
  42. ncbi Chondroma of the nasal bone: a case report
    Suja Sreedharan
    Dept of ENT, Kasturba Medical College Hospital, Attavar, Mangalore, Karnataka, PIN 575001, India
    Ear Nose Throat J 85:44-6. 2006
    ..Since the first case report by Morgan in 1842, approximately 150 cases of head and neck chondroma have been recorded in the English-language literature...
  43. ncbi Intracranial falx chondroma: literature review and a case report
    Kostas N Fountas
    Department of Neurosurgery, University Hospital of Larisa, School of Medicine, University of Thessaly, Larisa, Greece
    Clin Neurol Neurosurg 110:8-13. 2008
    ..As a result, their diagnosis has remained a histopathologic one. In our current study, we present a case of a falcine intracranial chondroma. This case provided the opportunity to extensively review the pertinent literature.
  44. ncbi Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma
    Fausto J Rodriguez
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1844-53. 2007
    ..They differ pathologically from pulmonary cartilaginous hamartomas on the basis of the presence of a thin fibrous pseudocapsule, frequent bone metaplasia, and calcification, and also the absence of entrapped epithelium and fat...
  45. doi Oncological and functional results of cryosurgical therapy of enchondromas and chondrosarcomas grade 1
    I C M van der Geest
    Department of Orthopaedic Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands
    J Surg Oncol 98:421-6. 2008
    ..It is applied to enlarge the oncological margins of resection and to reduce the local recurrence rate. The objective of this study is to analyze the oncological and functional results...
  46. ncbi Rotator cuff impingement due to enchondroma of the acromion
    Néstor López-Martín
    Department of Orthopaedic Surgery, Fundacion Jimenez Diaz, Universidad Autonoma, Madrid, Spain
    Acta Orthop Belg 71:732-5. 2005
    ..Tumours located in the coracoacromial arch have been very rarely reported as a cause of subacromial impingement. To the best of our knowledge, this is the first description of subacromial impingement secondary to acromial enchondroma...
  47. ncbi [Clinicopathologic analysis of 154 cases of tumors and tumor-like lesions in the bones of hands and feet]
    Zhi ming Jiang
    Department of Pathology, Shanghai Sixth People s Hospital Attached to Jiao Tong University, Shanghai 200233, China
    Zhonghua Bing Li Xue Za Zhi 32:417-21. 2003
    ..To study the clinical and pathologic features of tumors and tumor-like lesions in the bones of hands and feet...
  48. ncbi NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia
    Chunying Yu
    Program in Developmental Biology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
    J Pathol 201:609-15. 2003
    ..As identification of the grade of cartilage neoplasia can sometimes be difficult using histology alone, the level of expression of CCN family members could be a useful adjunct in the determination of tumour grade...
  49. ncbi Resolution of chylothorax after resection of rib chondroma in a dog
    S Watine
    Small Animal Internal Medicine, Department of Clinical Sciences, College of Veterinary Medicine, University of Liege, 20 boulevard de Colonster B44, 4000 Liege, Belgium
    J Small Anim Pract 44:546-9. 2003
    ..An incisional biopsy was performed, which gave a histological diagnosis of chondroma. Resolution of the chylothorax after en-bloc surgical removal of the tumour suggested that the rib tumour was ..
  50. ncbi Enchondroma and chondrosarcoma of bone: clinical, radiologic, and histologic differentiation
    Scott D Weiner
    Summa Orthopaedics, Northeastern Ohio Universities College of Medicine, Akron, Ohio, USA
    Instr Course Lect 53:645-9. 2004
    ..Biopsies are not typically indicated because of the histologic similarity of benign and malignant cartilage lesions...
  51. ncbi Molecular analysis of the INK4A/INK4A-ARF gene locus in conventional (central) chondrosarcomas and enchondromas: indication of an important gene for tumour progression
    Hetty M van Beerendonk
    Department of Pathology, Leiden University Medical Centre, The Netherlands
    J Pathol 202:359-66. 2004
    ....
  52. ncbi [Cartilage tumours of the bone. Diagnosis and therapy]
    A Streitbuerger
    Klinik und Poliklinik für Allgemeine Orthopädie, Universitatsklinikum Munster, Albert Schweitzer Strasse 33, 48149 Munster
    Orthopade 35:871-81; quiz 882. 2006
    ..The cartilage tumours appear as benign lesions (e.g. chondroma), as borderline tumours (proliferative chondroma vs grade I chondrosarcoma) or as highly malignant ..
  53. ncbi Diagnostic value and limitations of fluorine-18 fluorodeoxyglucose positron emission tomography for cartilaginous tumors of bone
    Francis Young In Lee
    Department of Orthopaedic Surgery, College of Physicians and Surgeons of Columbia University, 622 West 168th Street, PH 11, New York, NY 10032, USA
    J Bone Joint Surg Am 86:2677-85. 2004
    ..In this study, we investigated the glucose metabolism of cartilage tumors measured by positron emission tomography and its correlation with histopathologic grades...
  54. ncbi Imaging of tumours of the foot and ankle
    P Van Dyck
    Dpt of Radiology, University Hospital Antwerp, Edegem, Belgium
    JBR-BTR 87:252-7. 2004
    ..This presentation aims to give an overview of bone and soft-tissue tumours of the foot and ankle and to discuss the strength of each imaging modality in the diagnosis...
  55. ncbi Case records of the Massachusetts General Hospital. Case 8-2005. A 10-year-old boy with pain in the right thigh
    Mark C Gebhardt
    Department of Orthopedics, Beth Israel Deaconess Medical Center, Boston, USA
    N Engl J Med 352:1122-9. 2005
  56. ncbi Concurrent periosteal chondroma and enchondroma of the fibula mimicking chondrosarcoma
    Yasuhiro Yamamoto
    Department of Orthopedic Surgery, Fujita Health University, Toyoake City, Aichi, Japan
    Skeletal Radiol 35:302-5. 2006
    We present a rare concurrence of enchondroma and periosteal chondroma in the right distal fibula that mimicked chondrosarcoma in a 13-year-old boy...
  57. ncbi Chondrosarcoma of the talus: a case report
    Levent Buluc
    Department of Orthopaedics and Traumatology, Kocaeli University School of Medicine, Kocaeli, Turkey
    J Foot Ankle Surg 44:292-6. 2005
    ..At 3 years' follow-up, there is no evidence of recurrence or metastasis. The patient can walk with slight limp without the aid of external support...
  58. ncbi Chondroid tumors arising from the meninges--report of 2 cases and review of the literature
    M Bergmann
    Institute of Clinical Neuropathology, Klinikum Bremen Ost, Bremen, Germany
    Clin Neuropathol 23:149-53. 2004
    ..In case 1, a 19-year-old woman, a chondroma of the falx cerebri with extensive secondary ossification was diagnosed...
  59. ncbi Benign and malignant cartilage tumors of the hand
    Mary I O'Connor
    Department of Orthopedic Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Hand Clin 20:317-23, vi. 2004
    ..Chondrosarcoma is rare and most likely the result of malignant degeneration of a pre-existing lesion. Wide en bloc resection is appropriate for chondrosarcoma and typically involves ray resection or partial hand amputation...
  60. ncbi Differentiating clinical and radiographic features of enchondroma and secondary chondrosarcoma in the foot
    Donald A Gajewski
    Department of Orthopaedic Surgery and Rehabilitation, Walter Reed Army Medical Cente, Washington, D C 20307, USA
    Foot Ankle Int 27:240-4. 2006
    ..In contrast to similar tumors in the appendicular skeleton, it is difficult to distinguish between these two tumors when they occur in the foot...
  61. ncbi Intra-articular chondroma of the knee
    S C Talwalkar
    Oldchurch Hospital, Waterloo Road, Romford, Essex, RM7 0BE, UK
    Skeletal Radiol 34:351-4. 2005
    ..We report a rare case of an intra-articular chondroma in a 16-year-old boy of Asian origin developing in the region of the medial femoral condyle of the femur and ..
  62. ncbi Chondroma or chondrosarcoma? An indication for sternum resection
    Thomas Muehlberger
    Department of Plastic Surgery, DRK Kliniken Berlin Westend, Humboldt Universitat, Berlin, Germany
    Plast Reconstr Surg 121:145e-146e. 2008
  63. ncbi D2-40 functions as an effective chondroid marker distinguishing true chondroid tumors from chordoma
    Jason T Huse
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, 6th Floor Founders, Philadelphia, PA 19104, USA
    Acta Neuropathol 113:87-94. 2007
    ..We also demonstrate D2-40 immunoreactivity in two cases of chordoid meningioma and, in doing so, tentatively provide a means to distinguish this tumor from chordoma...
  64. pmc A 36-year-old woman with posterior shoulder pain
    Kevin M MacDonald
    Department of Orthopedics and Rehabilitation, University of Wisconsin, Box 7375 Clinical Science Center H4, 600 Highland Avenue, Madison, WI, 53792, USA
    Clin Orthop Relat Res 466:1010-4. 2008
  65. ncbi Non specific magnetic resonance features of chondromyxoid fibroma of the iliac bone
    E Yalniz
    Department of Orthopedic Surgery, Trakya University School of Medicine, Edirne, Turkey
    J BUON 12:407-9. 2007
    ..Magnetic resonance imaging (MRI) features were non specific for chondromyxoid fibroma. We emphasize the need to consider it in the differential diagnosis of chondrosarcoma...
  66. ncbi Periosteal chondroid tumors: radiologic evaluation with pathologic correlation
    P Robinson
    Department of Medical Imaging, Mount Sinai Hospital and the University Health Network, University of Toronto, 600 University Ave, Toronto, Ontario, Canada M5G 1X5
    AJR Am J Roentgenol 177:1183-8. 2001
    ..After the evaluation, a radiologic diagnosis of chondroma or chondrosarcoma was obtained...
  67. ncbi [Benign cartilaginous tumors]
    R Erlemann
    , St. Johannes-Hospital, An der Abtei 7-11, 47166 Duisburg
    Radiologe 41:548-59. 2001
    ..Clinics, localization, age distribution and morphology of benign cartilaginous tumors are presented and the most important differential diagnoses are given...
  68. ncbi Tumoral mass on a phalangeal bone in a 19-year-old
    Alpaslan Oztürk
    Bursa High Specialty Research and Education Hospital, Turkey
    Clin Orthop Relat Res 458:229-34. 2007
  69. ncbi [MRI in the diagnosis of tumors of the shoulder girdle area]
    I Schlecht
    Strahlenklinik und Poliklinik, ,
    Rontgenpraxis 53:191-5. 2001
    ..Estimation of the dignity in the case of infiltrative growth was possible in most cases. To assess the exact type of tumor was often difficult. Especially the dignity of the cartilaginous tumors could not be precisely described...
  70. ncbi Cartilaginous lesions of bone
    K K Unni
    Mayo Clinic, Department of Laboratory Medicine and Pathology, 200 First Street SW, Rochester, MN 55905, USA
    J Orthop Sci 6:457-72. 2001
    ..Most cartilaginous lesions are benign or of low-grade malignancy. However, there are some subtypes of chondrosarcoma that behave in a highly aggressive fashion...
  71. ncbi An association between cartilaginous tumours and breast cancer in the national pathology registration in The Netherlands points towards a possible genetic trait
    A E Odink
    Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands
    J Pathol 193:190-2. 2001
    ..e. 51 years versus 60.9 years. The association of breast cancer and cartilaginous tumours and the early age of onset of breast cancer in these patients may suggest a genetic trait...
  72. ncbi Endogenous secretory receptor for advanced glycation endproducts as a novel prognostic marker in chondrosarcoma
    Akihiko Takeuchi
    Department of Orthopaedic Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Cancer 109:2532-40. 2007
    ....
  73. ncbi Coccidioidomycosis fungal infection in the hand mimicking a metacarpal enchondroma
    J I Huang
    Department of Radiological Sciences and the Department of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles, California, USA
    J Hand Surg Br 25:475-7. 2000
    ..Curettage and bone grafting in combination with long-term antifungal therapy are necessary for successful treatment of coccidioidomycosis of the hand...
  74. ncbi Pathologic fracture of metacarpal enchondroma: case study and differential diagnosis
    Michael J McVey
    Department of Radiology, Logan College of Chiropractic, Chesterfield, MO 63003 1065, USA
    J Manipulative Physiol Ther 25:340-4. 2002
    ..Additionally, a reasonable list of differential considerations is presented with accompanying radiographic and advanced imaging characteristics...
  75. ncbi Immunohistochemical analysis of matrix metalloproteinase-1, -3, and -13 in naturally occurring cartilaginous tumors of dogs
    Keiichi Kuroki
    Comparative Orthopaedic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
    Am J Vet Res 63:1285-91. 2002
    ....
  76. ncbi Solitary enchondromas: is radiographic follow-up sufficient in patients with asymptomatic lesions?
    P E Müller
    Department of Orthopaedics, Universitat Rostock, Ulmenstr 44 45, 18055 Rostock, Germany
    Acta Orthop Belg 69:112-8. 2003
    ..On the other hand the complication rate of enchondroma curettage is considerable. Regular radiological follow-up of asymptomatic enchondromas may therefore be the better option...
  77. doi Juvenile juxtacortical chondromyxoid fibroma of bone: a case report
    Darshana Jhala
    Department of Pathology, University of Alabama at Birmingham, Louisville, KY 35233, USA
    Hum Pathol 39:960-5. 2008
    ..Juxtacortical CMF has not proven to be unusually aggressive in adults nor in this child, and marginal (en-block) resection remains the treatment of choice...
  78. ncbi Ultrasound and MR findings in tumor and tumor-like lesions of the fingers
    A Bueno Horcajadas
    Department of Radiology, Fundacion Hospital de Alcorcon, C Budapest, 1, 28922 Alcorcon, Madrid, Spain
    Eur Radiol 13:672-85. 2003
    ..We present representative cases selected from 62 patients evaluated at our institution, with pathologic correlation...
  79. ncbi Differential expression of runx2 and Indian hedgehog in cartilaginous tumors
    Hye Rim Park
    Department of Pathology, Hallym University, Anyang, Korea
    Pathol Oncol Res 13:32-7. 2007
    ..Ihh expression is considered a marker of the hypertrophic stage of differentiation in these tumor cells...
  80. ncbi Enchondroma protuberans of the hand
    Yeong Yi An
    Department of Radiology, The Catholic University of Korea, St Vincent s Hospital, 93 Ji dong, Paldal Ku, Suwon, Kyunggi do 442 723, Republic of Korea
    AJR Am J Roentgenol 190:40-4. 2008
    ..The purpose of this study was to describe imaging findings of this disease that were obtained using both radiography and MRI...
  81. ncbi [Is the rings and arcs pattern of mineralization specific for chondroid matrix tumors?]
    O Hauger
    Service de Radiologie A, Hopital Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux
    J Radiol 84:1012-6. 2003
    ..The authors report four cases of osteoblastomas in which the presence of such a pattern of mineralization mistakenly lead to a diagnosis of cartilaginous tumor. These densities are not explained by the histologic findings...
  82. ncbi Malignant transformation in human chondrosarcoma cells supported by telomerase activation and tumor suppressor inactivation
    James A Martin
    Department of Orthopaedic Surgery, The University of Iowa, Iowa City, Iowa 52242, USA
    Cell Growth Differ 13:397-407. 2002
    ..These observations may lead to better understanding of the factors responsible for malignant transformation, local recurrence, and metastases of cartilage neoplasms...
  83. ncbi Magnetic resonance imaging of bone tumours and mimics: pictorial essay
    Alison R Spouge
    Department of Diagnostic Imaging, University of Western Ontario, London Health Sciences Centre University Campus, 339 Windermere Rd, London, ON N6A 5A5
    Can Assoc Radiol J 54:221-33. 2003
  84. ncbi Treatment of solitary enchondromas in fingers
    E Kuur
    Department of Hand Surgery, University Hospital, Odense, Denmark
    J Hand Surg Br 14:109-12. 1989
    ..It is important that all material is removed from the cyst, which has to be packed completely with bone chips. The possibility of malignant change in enchondromas should be borne in mind, but we did not see this...
  85. ncbi Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature
    Lester D R Thompson
    Department of Endocrine and Otorhinolaryngic Head and Neck Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Am J Surg Pathol 26:836-51. 2002
    ..An associated benign chondroma with (n = 41 tumors) or without ischemia (n = 24 tumors) was noted...
  86. ncbi Chondrosarcoma of the arytenoid cartilage
    Sohit P Kanotra
    Department of Otorhinolaryngology, Government Medical College Srinagar, Kashmir, India
    Ear Nose Throat J 89:E6-E10. 2010
    ..occurrence, its indolent pattern of growth, and the difficulty in differentiating it histopathologically from chondroma. However, suspicion of arytenoid chondrosarcoma may be raised by a finding of its characteristic appearance as a ..
  87. doi Imaging modalities to access bony tumors and hyperplasic reactions of the temporomandibular joint
    Werner H Shintaku
    Department of Diagnostic Science, University of Texas Health Science Center at San Antonio Dental School, San Antonio, TX 78229 3900, USA
    J Oral Maxillofac Surg 68:1911-21. 2010
    ..for benign hyperplastic bony lesions in the TMJ should include condylar hyperplasia, osteochondroma, osteoma, chondroma, and osteoblastoma. If malignant features are present, chondrosarcoma and osteosarcoma should be considered...
  88. doi Clinical, radiologic and pathologic characteristics of the Carney triad: a case report and literature review
    Chin Fan Chen
    Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 26:428-34. 2010
    ..or metachronous condition involving gastric leiomyosarcoma, extra-adrenal paraganglioma and pulmonary chondroma. A 26-year-old woman presented with dizziness and several episodes of melena over 3 days...
  89. ncbi Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group
    Giovanni Tallini
    Department of Pathology, Yale University School of Medicine, New Haven, USA
    J Pathol 196:194-203. 2002
    ..abnormal cartilaginous tumours, loss of distal 8q was associated with osteochondroma, +5 with synovial chondroma/chondromatosis and parosteal or soft tissue chondroma, alterations of chromosome arm 6q with chondromyxoid ..
  90. ncbi Chondrosarcoma of the larynx: presentation of a case and review of the literature
    Santino Rizzo
    Otolaryngology Clinic, University of Perugia, Terni, Italy
    Tumori 94:864-8. 2008
    ..and the low degree of malignancy with which most cases present and which often causes it to be mistaken for a chondroma. A case is presented of a 61-year-old woman with a chondrosarcoma of the larynx, grade 2, originating from the ..
  91. doi Joint infection after knee arthroscopy: medicolegal aspects
    S Marmor
    Orthopaedic Department, Diaconesse Hospital Croix Saint Simon, 125, rue Avron, 75020 Paris, France
    Orthop Traumatol Surg Res 95:278-83. 2009
    ..This study analyzes the context of such infection occurrences, their management as well as their medicolegal consequences...
  92. doi Subungual tumors: clinicopathologic correlation with US and MR imaging findings
    Hye Jin Baek
    Department of Radiology, College of Medicine, Inje University, Busan Paik Hospital, Busanjin Ku, Busan, Korea
    Radiographics 30:1621-36. 2010
    ..can affect the subungual space, including benign solid tumors (glomus tumor, subungual exostosis, soft-tissue chondroma, keratoacanthoma, hemangioma, lobular capillary hemangioma), benign cystic lesions (epidermal and mucoid cysts), ..
  93. ncbi [The quantification of the magnetization transfer contrast (MTC) effect by calculating MT quotients: does it yield additional information for the differentiation of benign and malignant diseases of the locomotor apparatus?]
    M Vahlensieck
    Radiologische Universitätsklinik Bonn
    Rofo 171:468-72. 1999
    ..To investigate the potential information of the amount of magnetization-transfer effect in musculoskeletal lesions and to compare MT ratios from benign and malignant musculoskeletal lesions...
  94. doi Functional and biological analysis of Bcl-xL expression in human osteosarcoma
    Zhao Xia Wang
    Department of Oncology, The Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan Road, Nanjing 210011, PR China
    Bone 47:445-54. 2010
    ..Moreover, the levels of Bcl-xL mRNA expression were significantly higher in osteosarcoma tissues than those in chondroma or corresponding non-tumor tissues (P<0...
  95. ncbi Separate occurrence of extra-adrenal paraganglioma and gastrointestinal stromal tumor in monozygotic twins: probable familial Carney syndrome
    Liliane Boccon-Gibod
    Department of Pathology, University School of Medicine of Paris VI and Hôpital d Enfants Armand Trousseau Assistance Publique Hôpitaux de Paris, 26 avenue du Docteur Arnold Netter, 75571, Paris Cedex 12, France
    Pediatr Dev Pathol 7:380-4. 2004
    The nonfamilial Carney triad includes paraganglioma, gastrointestinal stromal tumor (GIST), and pulmonary chondroma. Some paraganglioma-GIST diads are familial and inherited in an apparent autosomal dominant manner...
  96. doi Pediatric rib lesions: a 13-year experience
    Sendia Kim
    Department of Surgery, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr Surg 43:1781-5. 2008
    ..Rib lesions in the pediatric population are rare but significant processes and are often neoplastic...
  97. ncbi Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature
    Markku Miettinen
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, 6825 16th Street NW, Bldg 54, Rm G090, Washington, DC 20306 6000, USA
    Am J Surg Pathol 29:1373-81. 2005
    ..Only 1 patient had Carney triad with pulmonary chondroma. None of the patients had family members with GIST. The tumors measured from 1.5 to 24 cm (median, 5.6 cm)...
  98. doi Extraskeletal osteochondroma near the hip: a pediatric case
    Zhen Jiang Liu
    Department of Pediatric Orthopedics, The Shengjing Hospital, China Medical University, Heping District, Shenyang, Liaoning, PR China
    J Pediatr Orthop B 19:524-8. 2010
    ..a lipomatous lesion, a pseudomalignant osseous tumour, an ossifying fibromyxoid tumour, an extraskeletal chondroma with endochondral ossification, synovial (osteo) chondromatosis, tumoural calcinosis, a synovial sarcoma and an ..
  99. ncbi [Primary benign chest wall tumors: results of surgical treatment]
    Rigoberto Dolores-Velázquez
    Subdirección de Cirugía, Instituto Nacional de Cancerología de México, Toluca, Mexico
    Cir Cir 75:419-24. 2007
    ..We undertook this study to describe the clinical characteristics of primary benign chest wall tumors and to evaluate the results of surgical treatment...
  100. pmc Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:53-64. 2010
    ..leiomyosarcoma [later renamed gastrointestinal stromal tumor (GIST)], extra-adrenal paraganglioma, and pulmonary chondroma. The disorder affected mostly young women and was not familial...
  101. ncbi Extraskeletal osteochondroma in the nape of the neck: a case report
    R Singh
    Department of Orthopaedic Surgery, Pt BD Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
    J Orthop Surg (Hong Kong) 14:192-5. 2006
    ..a lipomatous lesion, a pseudomalignant osseous tumour, an ossifying fibromyxoid tumour, an extraskeletal chondroma with endochondral ossification, synovial (osteo) chondromatosis, tumoural calcinosis, a synovial sarcoma, and an ..

Research Grants1

  1. In vivo Ribosome Tagging in Neuroendocrine Cell Types
    PAUL AMIEUX; Fiscal Year: 2008
    ..Low, medium, and highly translated mRNAs expressed in specific neuroendocrine cell types under varying physiological states can then be analyzed on microarrays followed by Quantitative-PCR. [unreadable] [unreadable]..