infantile diarrhea

Summary

Summary: DIARRHEA occurring in infants from newborn to 24-months old.

Top Publications

  1. ncbi Non-bacterial diarrhoea in children in the Philippines
    E Paje Villar
    Department of Paediatrics, University of Santo Tomas, Manila, Philippines
    Ann Trop Med Parasitol 88:53-8. 1994
  2. pmc Zinc in human health: effect of zinc on immune cells
    Ananda S Prasad
    Wayne State University School of Medicine, Detroit, Michigan 48201, United States of America
    Mol Med 14:353-7. 2008
  3. ncbi G and P rotavirus genotypes in stool samples from children in Teresina, State of Piauí
    Carla Isabel Macedo
    Institute Pasteur São Paulo, SP Brasil
    Rev Soc Bras Med Trop 40:381-4. 2007
  4. ncbi Virus diversity of acute diarrhea in tropical highlands
    Maria Fernanda Gutierrez
    Department of Microbiology, School of Science, Universidad Javeriana, Carrera edificio Felix Restrepo Of 313, Bogota, Colombia
    Rev Latinoam Microbiol 48:17-23. 2006
  5. ncbi Prevalence and genetic diversity of astroviruses in children with and without diarrhea in São Luís, Maranhão, Brazil
    Yvone B Gabbay
    Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministerio da Saude, 67030 000 Ananindeua, PA, Brazil
    Mem Inst Oswaldo Cruz 100:709-14. 2005
  6. pmc The magnitude of the global problem of diarrhoeal disease: a ten-year update
    C Bern
    Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta, GA 30333
    Bull World Health Organ 70:705-14. 1992
  7. pmc A localized adherence-like pattern as a second pattern of adherence of classic enteropathogenic Escherichia coli to HEp-2 cells that is associated with infantile diarrhea
    I C Scaletsky
    Department of Microbiology, Immunology, and Parasitology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil
    Infect Immun 67:3410-5. 1999
  8. ncbi Rotavirus vaccines: current prospects and future challenges
    Roger I Glass
    Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Lancet 368:323-32. 2006
  9. ncbi Intractable diarrhea with "phenotypic anomalies" and tricho-hepato-enteric syndrome: two names for the same disorder
    Alexandre Fabre
    Multidisciplinary Paediatric Department, Children Hospital of La Timone, Boulevard Jean Moulin, Marseille Cedex, France
    Am J Med Genet A 143:584-8. 2007
  10. ncbi Infantile systemic hyalinosis presenting as intractable infantile diarrhea
    Luluah Al-Mubarak
    Division of Dermatology, Department of Medicine, King Fahad National Guard Hospital, P O Box 22490, Riyadh, 11426, Kingdom of Saudi Arabia
    Eur J Pediatr 168:363-5. 2009

Research Grants

  1. Transporter Trafficking Mechanisms in Infectious Diarrhea
    Pradeep K Dudeja; Fiscal Year: 2013
  2. Structural insight into novel mechanisms of type III secretion
    CHARALAMPOS KALODIMOS; Fiscal Year: 2011
  3. Structural insight into novel mechanisms of type III secretion
    CHARALAMPOS KALODIMOS; Fiscal Year: 2013
  4. THE CLONAL NATURE OF CYTOTOXIGENIC E. COLI
    THOMAS WHITTAM; Fiscal Year: 1991
  5. THE CLONAL NATURE OF CYTOTOXIGENIC E. COLI
    THOMAS WHITTAM; Fiscal Year: 1992
  6. INTERNATIONAL VACCINE PROGRAM
    Jean Pape; Fiscal Year: 1993
  7. MOLECULAR GENETICS OF ENTEROPATHOGENIC E COLI ADHESION
    JAMES KAPER; Fiscal Year: 1991
  8. VIRAL GASTROENTERITIS--BASIS OF PROTECTION AND VIRULENCE
    Harry Greenberg; Fiscal Year: 1991
  9. CLINICAL EXPERIMENT OF HELICOBACTOR PYLORI TRANSMISSION
    Julie Parsonnet; Fiscal Year: 2005
  10. Modulation of NHE Activity by EPEC Infection
    Pradeep Dudeja; Fiscal Year: 2006

Detail Information

Publications189 found, 100 shown here

  1. ncbi Non-bacterial diarrhoea in children in the Philippines
    E Paje Villar
    Department of Paediatrics, University of Santo Tomas, Manila, Philippines
    Ann Trop Med Parasitol 88:53-8. 1994
    ....
  2. pmc Zinc in human health: effect of zinc on immune cells
    Ananda S Prasad
    Wayne State University School of Medicine, Detroit, Michigan 48201, United States of America
    Mol Med 14:353-7. 2008
    ..Zinc also is an antioxidant and has anti-inflammatory actions. The therapeutic roles of zinc in acute infantile diarrhea, acrodermatitis enteropathica, prevention of blindness in patients with age-related macular degeneration, ..
  3. ncbi G and P rotavirus genotypes in stool samples from children in Teresina, State of Piauí
    Carla Isabel Macedo
    Institute Pasteur São Paulo, SP Brasil
    Rev Soc Bras Med Trop 40:381-4. 2007
    ..The high percentage of mixtures and unusual combinations containing mixtures of human and animal rotavirus genotypes strongly suggests the possibility of gene reassortment and interspecies transmission...
  4. ncbi Virus diversity of acute diarrhea in tropical highlands
    Maria Fernanda Gutierrez
    Department of Microbiology, School of Science, Universidad Javeriana, Carrera edificio Felix Restrepo Of 313, Bogota, Colombia
    Rev Latinoam Microbiol 48:17-23. 2006
    ..03) or parasite (p < 0.00014) related IAD was prevalent from May to October. The mild seasonal weather changes don't seem to be associated with any other microbial agent...
  5. ncbi Prevalence and genetic diversity of astroviruses in children with and without diarrhea in São Luís, Maranhão, Brazil
    Yvone B Gabbay
    Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministerio da Saude, 67030 000 Ananindeua, PA, Brazil
    Mem Inst Oswaldo Cruz 100:709-14. 2005
    ..No seasonal pattern of occurrence was observed during these two years of study, and peak detection rate was observed in children aged between 3 and 6 months in the symptomatic group, and between 18 and 24 months in the controls...
  6. pmc The magnitude of the global problem of diarrhoeal disease: a ten-year update
    C Bern
    Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta, GA 30333
    Bull World Health Organ 70:705-14. 1992
    ....
  7. pmc A localized adherence-like pattern as a second pattern of adherence of classic enteropathogenic Escherichia coli to HEp-2 cells that is associated with infantile diarrhea
    I C Scaletsky
    Department of Microbiology, Immunology, and Parasitology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil
    Infect Immun 67:3410-5. 1999
    ..Strains with a localized adherence-like pattern (atypical EPEC) were found significantly more frequently (P = 0.028) in cultures from children with diarrhea (17.5%) than in controls (2.5%)...
  8. ncbi Rotavirus vaccines: current prospects and future challenges
    Roger I Glass
    Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Lancet 368:323-32. 2006
    ....
  9. ncbi Intractable diarrhea with "phenotypic anomalies" and tricho-hepato-enteric syndrome: two names for the same disorder
    Alexandre Fabre
    Multidisciplinary Paediatric Department, Children Hospital of La Timone, Boulevard Jean Moulin, Marseille Cedex, France
    Am J Med Genet A 143:584-8. 2007
    ..The acknowledgment that these two syndromes represent the same disease is a crucial step toward a better description of this syndrome and its outcome toward studies of the underlying genetic cause...
  10. ncbi Infantile systemic hyalinosis presenting as intractable infantile diarrhea
    Luluah Al-Mubarak
    Division of Dermatology, Department of Medicine, King Fahad National Guard Hospital, P O Box 22490, Riyadh, 11426, Kingdom of Saudi Arabia
    Eur J Pediatr 168:363-5. 2009
    ..Here we report a Saudi infant with infantile systemic hyalinosis who presented with intractable diarrhea, and we review the literature emphasizing recent developments in the molecular genetics of this disease...
  11. ncbi Intractable diarrhea of infancy with facial dysmorphism, trichorrhexis nodosa, and cirrhosis
    Maeran C Landers
    Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97201, USA
    Pediatr Dermatol 20:432-5. 2003
    ..Dermatologists should be aware of this syndrome in which trichorrhexis nodosa is commonly seen...
  12. ncbi Effect of community-based promotion of exclusive breastfeeding on diarrhoeal illness and growth: a cluster randomised controlled trial
    Nita Bhandari
    Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India
    Lancet 361:1418-23. 2003
    ..Exclusive breastfeeding is recommended until age 6 months. We assessed the feasibility, effectiveness, and safety of an educational intervention to promote exclusive breastfeeding for this length of time in India...
  13. ncbi Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy
    Caleb K King
    University of North Carolina Chapel Hill, North Carolina, USA
    MMWR Recomm Rep 52:1-16. 2003
    ..In the United States, adoption of these updated recommendations could substantially reduce medical costs and childhood hospitalizations and deaths caused by diarrhea...
  14. pmc Simultaneous zinc and vitamin A supplementation in Bangladeshi children: randomised double blind controlled trial
    M M Rahman
    International Centre for Diarrhoeal Disease Research, Dhaka 1000, Bangladesh
    BMJ 323:314-8. 2001
    ..To evaluate the effect of simultaneous zinc and vitamin A supplementation on diarrhoea and acute lower respiratory infections in children...
  15. ncbi High prevalence of atypical enteropathogenic Escherichia coli (EPEC) in Norwegian children with diarrhoea
    Jan E Afset
    Laboratory of Medical Microbiology, St Olav s Hospital, University Hospital, N 7006 Trondheim, Norway
    J Med Microbiol 52:1015-9. 2003
    ..None of the EPEC isolates were genetically related. This study demonstrates that atypical EPEC of non-EPEC serogroups is highly prevalent among Norwegian children with diarrhoea...
  16. pmc Life-threatening infantile diarrhea from fluoroquinolone-resistant Salmonella enterica typhimurium with mutations in both gyrA and parC
    Hideo Nakaya
    Kansai Medical University Kohri Hospital, Osaka, Japan
    Emerg Infect Dis 9:255-7. 2003
    ..The patient responded to antibiotic therapy with fosfomycin. Multidrug-resistance may become prevalent in Salmonella infections in Japan, as shown in this first case of a patient infected with fluoroquinolone-resistant Salmonella...
  17. ncbi Risk factors for childhood diarrhea incidence: dynamic analysis of a longitudinal study
    Bernd Genser
    Instituto De Saude Coletiva, Federal University of Bahia, Salvador, Brazil
    Epidemiology 17:658-67. 2006
    ..However, most studies have neglected important dynamic features of the longitudinal design and hierarchical interrelationships among the potential risk factors...
  18. ncbi A randomized controlled trial to evaluate the efficacy of lactobacillus GG in infantile diarrhea
    Sudipta Misra
    Department of Pediatrics, UIC College of Medicine at Peoria, Children s Medical Center, Medical College of Georgia, Augusta, GA 30912, USA
    J Pediatr 155:129-32. 2009
    ..There was no difference in groups in the duration of diarrhea or numbers of stool on days 3, 6, or 10 of treatment...
  19. ncbi Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials
    H Szajewska
    Department of Pediatric Gastroenterology and Nutrition, The Medical University of Warsaw, Warsaw, Poland
    J Pediatr Gastroenterol Nutr 33:S17-25. 2001
    ..This review was designed to assess the evidence from randomized controlled trials on effects of probiotics in the treatment and prevention of acute infectious diarrhea in infants and children...
  20. ncbi Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial
    Shinjini Bhatnagar
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
    J Pediatr Gastroenterol Nutr 38:34-40. 2004
    ..The authors evaluated the effect of zinc treatment as an adjunct to oral rehydration therapy on stool output and diarrheal duration in children with acute noncholera diarrhea with dehydration...
  21. ncbi Childhood diarrhea and observed hygiene behavior in Salvador, Brazil
    A Strina
    Institute of Public Health, Federal University of Bahia, Salvador, Brazil
    Am J Epidemiol 157:1032-8. 2003
    ..The relative risk for prevalence was 2.2 (95% confidence interval: 1.7, 2.8). The relative risk fell to 1.9 (95% confidence interval: 1.5, 2.5) after data were controlled for confounding, but the difference was still highly significant...
  22. pmc The global burden of diarrhoeal disease in children
    Umesh D Parashar
    Bull World Health Organ 81:236. 2003
  23. ncbi Safety and efficacy of a premixed, rice-based oral rehydration solution
    Irene Maulen-Radovan
    Diarrheal Disease Research Unit of the National Pediatrics Institute, Mexico City, Mexico
    J Pediatr Gastroenterol Nutr 38:159-63. 2004
    ....
  24. ncbi [Oral rehydration with a plantain flour-based solution precooked with standardized electrolytes]
    Carlos Bernal
    Departamento de Pediatría y Puericultura, Universidad de Antioquia, Medellin, Colombia
    Biomedica 25:11-21. 2005
    ..A preparation consisting of a precooked plantain flour-based solution and standard rehydration electrolytes was examined for its effectiveness in treating dehydration, as well as its anti-diarrhoeal properties...
  25. ncbi [Oral hydratation with a low osmolality solution in dehydrated children with diarrheic diseases: controlled clinical trial]
    Carlos Bernal
    Departamento de Pediatría y Puericultura, Universidad de Antioquia, Medellin, Colombia
    Biomedica 23:47-59. 2003
    ..8% in group 2 (p = 0.03). In treating dehydrated children, the low-osmolarity solution diminished the need for intravenous solutions, corrected most plasmatic sodium disorders, and produced no-risk of developing hyponatremia...
  26. pmc Microvillous inclusion disease (microvillous atrophy)
    Frank M Ruemmele
    INSERM EMI 0212, Pediatric Gastroenterology, Hepatology and Nutrition, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Orphanet J Rare Dis 1:22. 2006
    ..Early small bowel transplantation resulting in intestinal autonomy gives new hope for disease management and outcome...
  27. ncbi [Prognosis of rotavirus diarrhea]
    F Mota-Hernandez
    Departamento de Investigación en Medicina Comunitaria e Hidratación Oral, Hospital Infantil de Mexico Federico Gomez, Dr Marquez 162, 06720 Mexico, D F Mexico
    Salud Publica Mex 43:524-8. 2001
    ..To compare the severity of rotavirus diarrhea (RV) and non-rotavirus diarrhea...
  28. ncbi Incidence of nosocomial rotavirus infections, symptomatic and asymptomatic, in breast-fed and non-breast-fed infants
    P Gianino
    Department of Paediatrics, Regina Margherita Children s Hospital, University of Turin, Turin
    J Hosp Infect 50:13-7. 2002
    ..2 to 6.4 days. 10.6% of breast-fed infants and 32.4% of non-breast-fed infants contracted rotavirus infection (P<0.005). None of the breast-fed infants who contracted rotavirus infection developed diarrhoeic symptoms...
  29. ncbi Is a 2 : 1 ratio of standard WHO ORS to plain water effective in the treatment of moderate dehydration
    Elif Ozmert
    Department of Social Pediatrics, Hacettepe University Institute of Child Health, Ankara, Turkey
    J Trop Pediatr 49:291-4. 2003
    ..14 per cent, p = 0.2). A regimen of two parts of WHO ORS and one part of plain water may be an alternative treatment for moderately dehydrated children with non-cholera diarrhea in areas where hypotonic ORS is not yet available...
  30. ncbi Low osmolar oral rehydration salts solution in the treatment of acute watery diarrhoea in neonates and young infants: a randomized, controlled clinical trial
    A M Khan
    Clinical Sciences Division, ICDDR, B Centre for Health and Population Research GPO Box 128, Dhaka 1000, Bangladesh
    J Health Popul Nutr 23:52-7. 2005
    ..The results of the study indicate that ORS-75 is as safe as standard ORS-90 in the treatment of acute watery diarrhoea in neonates and very young infants and is effective in correcting and preventing dehydration...
  31. ncbi Limitations of probiotic therapy in acute, severe dehydrating diarrhea
    Hugo Costa-Ribeiro
    Department of Pediatrics, School of Medicine, Federal University of Bahia Salvador, Bahia, Brazil
    J Pediatr Gastroenterol Nutr 36:112-5. 2003
    ..However, beneficial effects appear to be limited to a modest decrease in the duration of diarrhea. No studies have evaluated this therapy in moderate to severe dehydrating diarrhea in a metabolic facility...
  32. ncbi CD10: a valuable tool for the light microscopic diagnosis of microvillous inclusion disease (familial microvillous atrophy)
    Gabriel M Groisman
    Department of Pathology, Hillel Yaffe Medical Center, Hadera, Israel
    Am J Surg Pathol 26:902-7. 2002
    ..We suggest that the definitive diagnosis of MID can be reached when small bowel biopsies from infants with intractable diarrhea display cytoplasmic staining of surface enterocytes with the above-mentioned stains...
  33. pmc HEp-2-adherent Escherichia coli strains associated with acute infantile diarrhea, São Paulo, Brazil
    Isabel C A Scaletsky
    Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil
    Emerg Infect Dis 8:855-8. 2002
    ..001). Atypical EPEC, showing a localized adherence-like pattern, was also more common in patients than controls (p>0.1). DAEC was isolated with equal frequency from patients and controls (p>0.1)...
  34. ncbi [Continuous oral hydration or with fractionated doses in acute diarrhea-induced dehydration in children]
    Felipe Mota-Hernández
    Servicio de Hidratación Oral, Departamento de Medicina Comunitaria, Hospital Infantil de Mexico Federico Gomez, Mexico, D F, Mexico
    Salud Publica Mex 44:21-5. 2002
    ..To evaluate the safety and effectiveness of two oral rehydration techniques...
  35. ncbi Reduced osmolarity oral rehydration solution for persistent diarrhea in infants: a randomized controlled clinical trial
    S A Sarker
    Clinical Sciences Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    J Pediatr 138:532-8. 2001
    ..No children in any of the treatment groups had hyponatremia. CONCLUSION: Reduced osmolarity ORS is clinically more effective than WHO-ORS and may thus be advantageous for use in the treatment of children with persistent diarrhea...
  36. ncbi Oral rehydration with a plantain flour-based solution in children dehydrated by acute diarrhea: a clinical trial
    M M Arias
    Faculty of Nursing, University of Antioquia, Medellin, Colombia
    Acta Paediatr 86:1047-51. 1997
    ..The plantain flour-based solution proved effective for the treatment of dehydration due to acute diarrheal diseases and should be considered as an alternative when standard WHO-ORS is not available...
  37. pmc Efficacy of standard glucose-based and reduced-osmolarity maltodextrin-based oral rehydration solutions: effect of sugar malabsorption
    M el Mougi
    Department of Paediatrics, Bab El Sha reya Hospital, Alazhar Faculty of Medicine, Cairo, Egypt
    Bull World Health Organ 74:471-7. 1996
    ..Studies are in progress to define the optimal formulation of reduced-osmolarity glucose-based ORS...
  38. pmc Does an L-glutamine-containing, glucose-free, oral rehydration solution reduce stool output and time to rehydrate in children with acute diarrhoea? A double-blind randomized clinical trial
    Claudia Gutiérrez
    Teaching Department and Nephrology Department, Hospital Infantil de Mexico Federico Gomez, Secretaria de Salud, Mexico City, Mexico
    J Health Popul Nutr 25:278-84. 2007
    ..An L-glutamine-containing glucose-free ORS seems not to offer greater clinical benefit than the standard WHO-ORS in mildly-to-moderately-dehydrated children with acute non-cholera diarrhoea...
  39. ncbi [Clinical study of acute diarrhea caused by rotavirus]
    Doina Mihalache
    Universitatea de Medicină şi Farmecie Gr T Popa Iaşi, Facultatea de Medicina, Clinica de Boli Infectioase
    Rev Med Chir Soc Med Nat Iasi 109:488-91. 2005
    ..Appropriate rehydration was necessary but only in 12 cases was made through intravenous access with: Ringer lactate, isotonic sodium chloride solutions. Most children recovered with in 5 days...
  40. ncbi [Epidemiology of rotaviral infections among children in Poland]
    Maria Korycka
    Powiatowa Stacja Sanitarno Epidemiologiczna w Zyrardowie
    Przegl Epidemiol 58:649-53. 2004
    ..Rotavirus is also accountable for rising of nosocomial infections. Summarizing, there is conclusion, that is necessary to implement the registration of rotaviral infections in Poland...
  41. ncbi The prevalence of diarrheal disease among Brazilian children: trends and differentials from 1986 to 1996
    Narayan Sastry
    RAND Corporation, 1700 Main Street, P O Box 2138, Santa Monica, CA 90407 2138, USA
    Soc Sci Med 60:923-35. 2005
    ....
  42. ncbi [Prospective follow-up of hospital-acquired diarrhoea in 28 paediatric wards of the south-east part of France during a winter season]
    A Thuret
    Service de Pediatrie, CHU de Saint Etienne, France
    Pathol Biol (Paris) 52:131-7. 2004
    ....
  43. ncbi [Nosocomial rotavirus infections]
    Maria Korycka
    Powiatowa Stacja Sanitarno Epidemiologiczna w Zyrardowie
    Przegl Epidemiol 58:467-73. 2004
    ..The only way of prevention of the rotaviral infections and nosocomial rotaviral infections is implementation of effective and save rotaviral vaccine, which will be suitable for infants and toddlers worldwide...
  44. ncbi Viremia and extraintestinal infections in infants with rotavirus diarrhea
    Ning Li
    Department of Pediatrics, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:643-8. 2003
    ..To test the hypothesis that viremia might be involved in infants with rotavirus (RV) diarrhea and extraintestinal infection...
  45. ncbi [Multidrug-resistant and fluoroquinolone-resistant Salmonella enterica serotype Typhimurium definitive phage type 12 isolated from infantile diarrhea]
    H Nakaya
    Department of Clinical Center Laboratory, Kansai Medical University
    Kansenshogaku Zasshi 75:815-8. 2001
    ..He was cured by antibiotic therapy using fosfomycin (< or = 1 microgram/ml). We could not determine a route of infection. Domestic surveillance for fluoroquinolon-resistant Sallmonella is necessary...
  46. ncbi [Factors of virulence associated with enteropathogenicity in strains of Aeromonas spp. isolated from children with diarrhea in Mérida, Venezuela]
    Aurora Longa
    Universidad de Los Andes, Merida, Venezuela
    Rev Cubana Med Trop 57:85-91. 2005
    ..Of the isolated species, Aeromonas caviae was the most frequently identified. All these results suggest that the Aeromonas species are potential enteric pathogens in this population...
  47. ncbi [From structural and antigenic features of the rotavirus to the development of the vaccines]
    N Parez
    Service des urgences pédiatriques, Hôpital d enfants A Trousseau, APHP, 26 rue du Dr Netter, 75571 Paris Cedex 12, France
    Arch Pediatr 14:S186-93. 2007
    ..The development of these two vaccines has followed two different strategies. Despite their differences, these vaccines are both safe and efficient in protecting young infants against severe rotavirus acute gastroenteritis...
  48. ncbi [Epidemiological and virological aspects Rotavirus diarrhoea in Abidjan, Côte d'Ivoire (1997-2000)]
    C Akoua-Koffi
    Département des virus ẃpidémiques, Institut Pasteur de Côte d Ivoire, BP 490 Abidjan 01, Cote d Ivoire
    Bull Soc Pathol Exot 100:246-9. 2007
    ..4%. These results will need to be completed by the determination of VP7 genotypes in order to provide interesting information on rotaviruses before the introduction of anti-Rotavirus vaccines in the country...
  49. ncbi [Viral acute diarrhea: clinical and evolutive aspects]
    J P Olives
    Gastroenérologie et Nutrition, Departement de Pediatrie, Hopital des Enfants, 330 av Grande Bretagne, BP 3119, 31059 Toulouse Cedex 9, France
    Arch Pediatr 14:S152-5. 2007
    ..Rotavirus infection causes severe gastroenteritis, particularly in infants under six months of age...
  50. ncbi Epidemiological aspects of human rotavirus infection in children hospitalized with acute gastroenteritis in an area of northern Italy
    Maria Cristina Medici
    Sezione di Microbiologia, Dipartimento di Patologia e Medicina di Laboratorio, Universita degli Studi di Parma, Parma, Italy
    Acta Biomed 75:100-6. 2004
    ..The epidemiological aspects of HRV infection, also compared to other enteric virus infections, will contribute to assess the magnitude of the problem of HRV in different settings and to devise strategies for intervention...
  51. ncbi Vaccines. Rotavirus vaccines' second chance
    Leslie Roberts
    Science 305:1890-3. 2004
  52. ncbi [Living with animals and rotavirus]
    María del R González-Losa
    Salud Publica Mex 50:271. 2008
  53. ncbi Pathogen-specific risk factors and protective factors for acute diarrheal illness in children aged 12-59 months in São Paulo, Brazil
    J Sobel
    Foodborne and Diarrheal Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Infect Dis 38:1545-51. 2004
    ..0; P<.05). In these poor households, 28% of cases of diarrhea in 1-4-year-old children was attributable to easily modifiable exposures...
  54. pmc Acute infantile gastroenteritis associated with human enteric viruses in Tunisia
    Khira Sdiri-Loulizi
    Centre National de Référence des Virus Entériques, Laboratoire de Virologie, Centre Hospitalier Universitaire de Dijon, 2 Boulevard Marechal de Lattre de Tassigny, BP 77908, F 21079 Dijon cedex, France
    J Clin Microbiol 46:1349-55. 2008
    ..No significant differences were observed between rotavirus and norovirus infections with regard to the incidence and the clinical severity of the disease, especially in dehydration...
  55. ncbi Australian Rotavirus Surveillance Program: annual report, 2006-07
    Carl D Kirkwood
    National Rotavirus Reference Centre, Murdoch Childrens Research Institute, Royal Children s Hospital Parkville, Victoria
    Commun Dis Intell Q Rep 31:375-9. 2007
    ..Uncommon rotavirus genotypes, G8 (n = 1) and G12 (n = 2) were identified in children with acute gastroenteritis during this study period...
  56. ncbi Apparent extinction of non-G2 rotavirus strains from circulation in Recife, Brazil, after the introduction of rotavirus vaccine
    T Nakagomi
    Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
    Arch Virol 153:591-3. 2008
    ..The introduction of a G1P[8] rotavirus vaccine in Recife, Brazil, caused a decrease in rotavirus detection from 27% (March-May, 2006) to 5.0% (March-May, 2007), with all strains becoming G2, against which less protection had been predicted...
  57. ncbi [Three kinds of viruses isolated from diarrhea patients of infants and preschool children in Fuzhou city]
    Jian min Gao
    School of Biological Engineering, Fujian Normal University, Fuzhou, 350007, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:456-7. 2004
  58. ncbi Antimicrobial use in children under five years with diarrhea in a central region province, Thailand
    N Howteerakul
    Department of Epidemiology, Faculty of Public Health, Mahidol University, Australia
    Southeast Asian J Trop Med Public Health 35:181-7. 2004
    ..Hopefully, such activities will help reduce the inappropriate use of antimicrobial agents in treating diarrheal disease...
  59. ncbi Breastfeeding and natural colonization with Lactobacillus spp as protection against rotavirus-associated diarrhea
    M L Guerrero
    Departamento de Infectologia, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Vasco de Quiroga No 15, Delegacion Tlalpan, México DF V 14000, Mexico
    Adv Exp Med Biol 554:451-5. 2004
  60. ncbi Rotavirus vaccines and the prevention of hospital-acquired diarrhea in children
    Thea K Fischer
    Epidemic Intelligence Service, Epidemiology Program Office, USA
    Vaccine 22:S49-54. 2004
    ..Development of safe and effective rotavirus vaccines will protect children worldwide against the severe consequences of rotavirus infections including prolonged hospitalizations for nosocomially acquired infections...
  61. ncbi National Rotavirus Surveillance Program annual report, 2005-06
    Carl D Kirkwood
    Murdoch Childrens Research Institute, Parkville, Victoria
    Commun Dis Intell Q Rep 30:434-8. 2006
    ..6%), serotype G9 (15.1%) and serotype G3 (14.7%). Genotype G12 strains were identified for the first time in Australia. As in previous years, there was substantial geographic variation in the prevalence of rotavirus serotypes...
  62. ncbi Rotavirus serotypes and electropherotypes identified among hospitalised children in São Luís, Maranhão, Brazil
    Cláudia Regina N E da Luz
    Hospital Universitario Materno Infantil, Universidade Federal do Maranhao, Sao Luis, Maranhao, Brazil
    Rev Inst Med Trop Sao Paulo 47:287-93. 2005
    ..These data underscore the importance of rotaviruses in the aetiology of severe infantile gastroenteritis in Northeastern Brazil and sustain the concept that a future vaccine should confer protection against more than one serotype...
  63. pmc Climatic factors associated with hospitalizations for rotavirus diarrhoea in children under 5 years of age
    R M D'Souza
    National Centre for Epidemiology and Population Health, The Australian National University, Canberra, ACT 0200, Australia
    Epidemiol Infect 136:56-64. 2008
    ..Strategies to combat outbreaks of rotavirus diarrhoea should take climatic factors and seasonal effects into consideration to plan for the excess seasonal hospital admissions...
  64. pmc Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens
    M Iturriza Gomara
    Enteric Virus Unit, Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 136:23-33. 2008
    ..Analysis of the questionnaires indicated that rotavirus infections were likely to be more severe than any other virus infection, and children from whom a viral pathogen was identified were more likely to require rehydration therapy...
  65. ncbi National Rotavirus Surveillance Program annual report, 2004-05
    Carl D Kirkwood
    Enteric Virus Research Group, Murdoch Childrens Research Institute, Royal Children s Hospital, Flemington Road, Parkville, VIC 3052
    Commun Dis Intell Q Rep 30:133-6. 2006
    ..3 per cent of all strains, followed by serotype G3 (36.7%) and serotype G9 (6.9%). As in previous years, there was substantial geographic variation in the prevalence of rotavirus serotypes...
  66. ncbi G-genotyping of rotaviruses in stool samples in Salento, Italy
    T Grassi
    Department of Biological and Environmental Sciences and Technologies, Lab of Hygiene, University of Lecce, Italy
    J Prev Med Hyg 47:138-41. 2006
    ..In this study, therefore, we demonstrate the usefulness of a simple method for correctly determining the G genotypes circulating in a geographic region...
  67. ncbi [Acute viral gastroenteritis in children]
    Elzbieta Ołdak
    Z Kliniki Obserwacyjno Zakańej Dzieci Akademii Medycznej, Białymstoku
    Wiad Lek 59:534-7. 2006
    ..Familiarity with molecular epidemiology of viruses and with their antigenic diversity allows to elaborate and apply the adequate vaccines as well as to initiate the prophylactic procedures...
  68. ncbi Active hospital-based surveillance of rotavirus diarrhea in Austrian children, period 1997 to 2003
    Pamela Rendi-Wagner
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University Vienna, and St Anna Kinderspital, Austria
    Wien Klin Wochenschr 118:280-5. 2006
    ..The aim of this study was to provide data on hospitalization of young children with rotavirus infection in Austria...
  69. ncbi Diagnostic value of bacterial stool cultures and viral antigen tests based on clinical manifestations of acute gastroenteritis in pediatric patients
    L J Liu
    Department of Pediatrics, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Eur J Clin Microbiol Infect Dis 24:559-61. 2005
    ..In conclusion, etiologic tests to determine the cause of childhood gastroenteritis according to their characteristic clinical features or laboratory test results, or both, are of low diagnostic value...
  70. pmc Molecular characterization of rotaviruses circulating in the population in Turkey
    O Cataloluk
    Department of Medical Biology and Genetics, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
    Epidemiol Infect 133:673-8. 2005
    ..This is the first molecular epidemiology study of its kind to be carried out in Turkey and suggests a significant diversity of co-circulating rotavirus strains...
  71. ncbi [Prospective study of rotaviral infections in children hospitalized at the Clinic of Pediatric Infectious Diseases in Białystok in 2003]
    Artur Sulik
    Klinika Obserwacyjno Zakaźna Dzieci Akademii Medycznej w Białymstoku
    Przegl Epidemiol 58:475-81. 2004
    ..This study delivers epidemiological data on rotavirus infection and shows the need of further study on etiology of viral gastroenteritis in children in our district...
  72. ncbi Does daily intake of bovine lactoferrin-containing products ameliorate rotaviral gastroenteritis?
    Masanori Egashira
    Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Acta Paediatr 96:1242-4. 2007
  73. ncbi Peak rotavirus activity shifted from winter to early spring in Japan
    Hiroshi Suzuki
    Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University, Graduate School of Medical and Dental Sciences, Niigata City, Niigata, Japan
    Pediatr Infect Dis J 24:257-60. 2005
    ..Earlier we confirmed their causation by rotaviruses but found peaks in January or February from 1974 to 1981. The aim of the present study was to confirm the temporal shift in peak rotavirus activity...
  74. ncbi Viral diarrhea in Japanese children: results from a one-year epidemiologic study
    Tung Gia Phan
    Department of Developmental Medical Sciences, Institute of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Lab 51:183-91. 2005
    ..Our findings confirmed the presence of many diarrheal viruses co-circulating among Japanese infants and children and showed the great genetic diversity among norovirus...
  75. pmc Disease burden due to enterotoxigenic Escherichia coli in the first 2 years of life in an urban community in Bangladesh
    Firdausi Qadri
    International Centre for Diarrheal Disease Research, Laboratory Sciences Division B, Dhaka 1000, Bangladesh
    Infect Immun 75:3961-8. 2007
    ..032 to 0.023). Children with ETEC diarrhea were underweight and growth stunted at the 2-year follow-up period, showing the importance of strategies to prevent and decrease ETEC diarrheal morbidity in children...
  76. ncbi Deaths from rotavirus disease in Bangladeshi children: estimates from hospital-based surveillance
    Go Tanaka
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
    Pediatr Infect Dis J 26:1014-8. 2007
    ..To assess the potential health benefits of introducing new rotavirus (RV) vaccines, we estimated mortality from RV gastroenteritis in Bangladeshi children <5 years of age...
  77. ncbi [Hospitalisation associated with Rotavirus gastroenteritis in Italy, 2001-2003, evaluated by means of ICD9-CM diagnostic codes]
    Alessia Marocco
    GlaxoSmithKline S p A, Verona
    Ig Sanita Pubbl 62:215-44. 2006
    ..A specific immunisation strategy, safe, effective, cost-effective and easy to perform, could have a great impact on the incidence of the disease and on the associated costs...
  78. ncbi Rotavirus and enteric pathogens in infantile diarrhoea in Manipal, South India
    Mamatha Ballal
    Department of Microbiology, Kasturba Medical College, Manipal, Karnataka, India
    Indian J Pediatr 69:393-6. 2002
    ..92%), along with cryptosporidium (6.47%) and candida albicans (3.98%). In a control group consisting of 100 children without history of diarrhoea, 2 were positive for rotavirus, 3 for cryptosporidium and 12 for Escherichia coli...
  79. ncbi Infantile viral gastroenteritis: on the way to closing the diagnostic gap
    R Simpson
    Clinical Microbiology and Public Health Laboratory, Addenbrooke s Hospital, Cambridge, United Kingdom
    J Med Virol 70:258-62. 2003
    ..However, additional work is required to reduce this deficit further by optimising sampling algorithms and by identifying other agents associated with viral gastroenteritis...
  80. ncbi Prevalence of viral, bacterial and parasitic enteropathogens among young children with acute diarrhoea in Jeddah, Saudi Arabia
    S M el-Sheikh
    Department of Microbiology, School of Medicine, King Abdulaziz University, PO Box 9029, Jeddah 21413, Saudi Arabia
    J Health Popul Nutr 19:25-30. 2001
    ..7% each), and Candida albicans (0.5%). Based on the results of this study, it is concluded that the high prevalence of the various enteropathogens among young children is a significant public health problem...
  81. ncbi [Etiology of acute diarrheas in children from the Lodz region. I. Occurrence of etiologic agents]
    Jolanta Zurawska-Olszewska
    Zakład Mikrobiologii Lekarskiej, Katedra Mikrobiologii AM w Łodzi
    Med Dosw Mikrobiol 54:129-36. 2002
    ..1%). The investigations enabled identification both the mixed infections (n = 25; 16.1%) and more rare etiologic agents of diarrhea...
  82. ncbi Diarrhoeal disease in children in Gaza
    S Sallon
    Department of Medical Microbiology, University of Liverpool
    Ann Trop Med Parasitol 88:175-82. 1994
    ..Twenty-one of the 29 children who died during the study died with diarrhoea and Cryptosporidium was detected in eight (38%) of these 21 children...
  83. ncbi Infectious diarrhea in children: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
    Geoffrey Davidson
    Commonwealth Association of Paediatric Gastroenterology and Nutrition, USA
    J Pediatr Gastroenterol Nutr 35:S143-50. 2002
  84. ncbi [Beliefs and knowledge of a group of doctors about the nutritional management of the child with acute diarrhea]
    Martha Corral-Terrazas
    Unidad de Investigacion Medica en Epidemiologia Clinica, Instituto Mexicano del Seguro Social IMSS Chihuahua, Chihuahua, Mexico
    Salud Publica Mex 44:303-14. 2002
    ..Physicians' dietary management was compared with that recommended by the World Health Organization...
  85. ncbi Diarrhoea and gastroenteritis in the infant and young child
    Nadeem Afzal
    Royal Free Hospital, London
    J Fam Health Care 12:146-50. 2002
    ..This article highlights basic principles of management of gastroenteritis in children. The aim is to produce easily understandable, usable and reproducible evidence-based guidelines...
  86. ncbi Role of human-milk lactadherin in protection against symptomatic rotavirus infection
    D S Newburg
    Shriver Center for Mental Retardation, Waltham, MA 02254, USA
    Lancet 351:1160-4. 1998
    ..Human milk contains a 46 kDa mucin-associated glycoprotein, lactadherin, which binds specifically to rotavirus and inhibits its replication. This study tested the hypothesis that lactadherin protects against symptoms of rotavirus infection...
  87. ncbi [The relationship of serum mitochondrial creatine kinase and rotavirus gastroenteritis in pediatric patients]
    T Hoshino
    Department of Clinical Pathology, Nihon University School of Medicine, Itabashi-ku, Tokyo 173-8610
    Rinsho Byori 49:597-602. 2001
    ..Elevated serum mCK level of rotavirus gastroenteritis patient may therefore reflect diffused intestinal epithelial cell damage...
  88. pmc Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunization
    N A Cunliffe
    Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Bull World Health Organ 76:525-37. 1998
    ..Wherever large numbers of cases of rotavirus diarrhoea occur early in infancy, immunization at birth may protect the children before their first symptomatic infection...
  89. ncbi Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children: a randomized, double blind, controlled trial
    Maria D Subbotina
    Department of Pediatric Infectious Disease, State Pediatric Medical Academy, Litovskaya Street 2, 194100 St Petersburg, Russia
    Pediatr Infect Dis J 22:706-11. 2003
    ..To determine the effectiveness of tormentil root extract (TRE) for treatment of rotavirus diarrhea in children...
  90. ncbi Rotaviral and bacterial gastroenteritis in children during winter: an evaluation of physician ordering patterns
    Roy F Chemaly
    Department of Clinical Pathology, Section of Clinical Microbiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue L40, Cleveland, OH 44185, USA
    J Clin Virol 28:44-50. 2003
    ..Identification of the agents of infectious diarrhea may facilitate appropriate therapy and prevent inappropriate antibiotic use...
  91. ncbi Incidence of Norwalk-like viruses, rotavirus and adenovirus infection in patients with acute gastroenteritis in Jakarta, Indonesia
    D Subekti
    U S Naval Medical Research Unit No 2, American Embassy Jakarta, Unit 8132, NAMRU 2, FPO AP, 96520 8132, Indonesia
    FEMS Immunol Med Microbiol 33:27-33. 2002
    ..The high incidence of enteric viral-related infections is a threat among acute diarrheic patients in Jakarta, Indonesia...
  92. ncbi The epidemiology of acute viral gastroenteritis in hospitalized children in Cordoba City, Argentina: an insight of disease burden
    M O Giordano
    , , , , Argentina
    Rev Inst Med Trop Sao Paulo 43:193-7. 2001
    ..The major impact on viral diarrhea lies on rotaviral infection, accounting for 84.0% of the viral diarrheal cases analyzed and for approximately one third of severe diarrheas requiring hospital admission in Córdoba City, Argentina...
  93. ncbi Detection and characterization of human rotavirus among children with diarrhoea in Botswana
    M Kasule
    Institute of Health Sciences, Gaborone, Botswana
    Trop Med Int Health 8:1137-42. 2003
    ..Mixed P-types P[4 + 6] (5%) and P[6 + 8] (18%) were also detected. Rotavirus strains G1 P[8] and GI P[6 + 8] were the most common cause of diarrhoea in our study area...
  94. ncbi [Diarrhoea-causing agents in children aged less than five in Tunja, Colombia]
    Fred G Manrique-Abril
    Escuela de Medicina Enfermería Universidad Pedagógica y Tecnológica de Columbia
    Rev Salud Publica (Bogota) 8:88-97. 2006
    ..Determining the prevalence and type of infectious ADD-causing agents in a sample of children aged less than five who consulted the IPS in Tunja during 2004...
  95. ncbi Oral bacterial therapy promotes recovery from acute diarrhea in children
    M C Lee
    Department of Pediatrics, Cathay General Hospital, 280, Section 4, Jen-Ai Road, Taipei, Taiwan
    Acta Paediatr Taiwan 42:301-5. 2001
    ..1 vs. 3.6 days, p < 0.01). Oral bacterial therapy is an effective adjuvant therapy in rotavirus positive and negative children with diarrhea and can safely be administered during an episode of acute diarrhea...
  96. ncbi Disease burden and risk factors for hospitalizations associated with rotavirus infection among children in New York State, 1989 through 2000
    Hwa Gan H Chang
    New York State Department of Health, Room 1143, Corning Tower Building, Empire State Plaza, Albany, NY 12237, USA
    Pediatr Infect Dis J 22:808-14. 2003
    ..To examine trends in hospitalizations for pediatric diarrhea, ascertain the disease burden and risk factors for hospitalizations associated with rotavirus and assess the accuracy of coding for rotavirus hospitalizations in New York State...
  97. ncbi Protective effect of breastfeeding on diarrhea among children in a rapidly growing newly developed society
    Mohammad S Ehlayel
    Unit of Allergy and Immunology, Department of Pediatrics, Hamad Medical Corporation, Qatar
    Turk J Pediatr 51:527-33. 2009
    ..the effect of exclusive breastfeeding (EBF) is encouraged since it has been found to be protective against infantile diarrhea. In a newly developing Qatar, modern water supply and sanitation facilities have become available to ..
  98. ncbi Epidemiology of rotavirus and astrovirus infections in children in northwestern Nigeria
    M Aminu
    Department of Microbiology, Faculty of Science, Ahmadu Bello University, Zaria Nigeria
    Ann Afr Med 7:168-74. 2008
    ..Human astroviruses have been identified as one of the most frequent causes of infantile diarrhea, second in incidence only to rotavirus...
  99. ncbi Cytokine stimulation of nitric oxide formation and differential regulation in hepatocytes and nonparenchymal cells of endotoxemic rats
    J A Spitzer
    Department of Physiology, Louisiana State University Medical Center, New Orleans 70112
    Hepatology 19:217-28. 1994
    Some disease processes in which increased endotoxin and cytokine levels exist (e.g., sepsis and infantile diarrhea) are also associated with increased levels of blood nitrates, the stable end products of nitric oxide...
  100. ncbi [Molecular epidemiology of human adenovirus diarrhea among infants and young children in Lanzhou from July 2005 to June 2008]
    Hong mei Qi
    Department of Pediatrics, First Hospital, Lanzhou University, Lanzhou 730000, China
    Zhonghua Er Ke Za Zhi 47:922-5. 2009
    ..Studies reported elsewhere have shown that about 8%-10% of cases with infantile diarrhea are caused by AdV and in some areas AdV diarrhea even occurred in the form of outbreaks...
  101. pmc Diarrhea-associated biofilm formed by enteroaggregative Escherichia coli and aggregative Citrobacter freundii: a consortium mediated by putative F pili
    Alex L Pereira
    Laboratorio de Microbiologia, Departamento de Biologia Celular, Universidade de Brasilia, Brasilia, DF, Brazil
    BMC Microbiol 10:57. 2010
    ..Citrobacter freundii is classically considered as an indigenous intestinal species that is sporadically associated with diarrhea...

Research Grants29

  1. Transporter Trafficking Mechanisms in Infectious Diarrhea
    Pradeep K Dudeja; Fiscal Year: 2013
    ..Enteropathogenic E. coli (EPEC), a food-borne pathogen, is a major cause of infantile diarrhea worldwide causing high rate of morbidity and mortality...
  2. Structural insight into novel mechanisms of type III secretion
    CHARALAMPOS KALODIMOS; Fiscal Year: 2011
    ..components from the enteropathogenic Escherichia coli (EPEC), a prototype for TTSS and the major cause of infantile diarrhea and child mortality worldwide...
  3. Structural insight into novel mechanisms of type III secretion
    CHARALAMPOS KALODIMOS; Fiscal Year: 2013
    ..components from the enteropathogenic Escherichia coli (EPEC), a prototype for TTSS and the major cause of infantile diarrhea and child mortality worldwide...
  4. THE CLONAL NATURE OF CYTOTOXIGENIC E. COLI
    THOMAS WHITTAM; Fiscal Year: 1991
    ..the 0157:H7 clone and a classical EPEC serotype (055:H7) that has long been associated with outbreaks of infantile diarrhea. This finding, as well as the observation that SLT genes occur in a diversity of E...
  5. THE CLONAL NATURE OF CYTOTOXIGENIC E. COLI
    THOMAS WHITTAM; Fiscal Year: 1992
    ..the 0157:H7 clone and a classical EPEC serotype (055:H7) that has long been associated with outbreaks of infantile diarrhea. This finding, as well as the observation that SLT genes occur in a diversity of E...
  6. INTERNATIONAL VACCINE PROGRAM
    Jean Pape; Fiscal Year: 1993
    ..Since 1980 this unit has conducted studies of infantile diarrhea, typhoid fever, sexually transmitted diseases, leprosy, tuberculosis, and particularly HIV infection and ..
  7. MOLECULAR GENETICS OF ENTEROPATHOGENIC E COLI ADHESION
    JAMES KAPER; Fiscal Year: 1991
    Enteropathogenic Escherichia coli (EPEC) are a significant cause of infantile diarrhea. The long-term objectives of this project are to study the pathogenesis of disease due to this organism and to develop DNA probes for diagnosis and ..
  8. VIRAL GASTROENTERITIS--BASIS OF PROTECTION AND VIRULENCE
    Harry Greenberg; Fiscal Year: 1991
    Human rotaviruses are the leading cause of severe infantile diarrhea in the world. In the immunocompromised or elderly adult, rotaviruses are also an important cause of diarrheal disease...
  9. CLINICAL EXPERIMENT OF HELICOBACTOR PYLORI TRANSMISSION
    Julie Parsonnet; Fiscal Year: 2005
    ..infection has been linked to increased risk for diarrheal disease, specifically, symptomatic cholera and infantile diarrhea. The investigators postulate that H...
  10. Modulation of NHE Activity by EPEC Infection
    Pradeep Dudeja; Fiscal Year: 2006
    ..coli (EPEC), an important food-borne pathogen, causes infantile diarrhea resulting in significant morbidity and mortality...
  11. Enteropathogenic E. coli Effects on Intestinal Function
    Gail A Hecht; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Enteropathogenic E. coli (EPEC), a cause infantile diarrhea, is associated with significant morbidity and mortality...
  12. Type IV Pilins as Vaccines against Bioterrorism Threats
    Michael Donnenberg; Fiscal Year: 2004
    ....
  13. Models of Birthweight and Low Birthweight
    Narayan Sastry; Fiscal Year: 2004
    ..The first is the 1997 Natality Data Set (NDS), compiled from birth certificates by the National Center for Health Statistics. The second data source is the 1988 National Maternal and Infant Health Survey (NMIHS). ..
  14. HOST CELLULAR RECEPTORS AND HUS
    DAVID NEWBURG; Fiscal Year: 2001
    ..Such information may identify aspects of HUS pathobiology that are amenable to therapeutic intervention and may aid in identifying patients at high risk for HUS who could be targeted for increased vigilance and prophylactic measures. ..
  15. Neighborhood and Family Effects on Stress and Health
    Narayan Sastry; Fiscal Year: 2008
    ..abstract_text> ..
  16. MOLECULAR BASIS OF LOCALIZED ADHERENCE IN E. COLI
    Michael Donnenberg; Fiscal Year: 2009
    ..The structure of the distantly related B6 variant of bundlin will be solved to shed light on the role of sequence variation in pilus structure and immunogenicity. ..
  17. Mucosal immune response to oral cholera vaccine Peru 15
    Firdausi Qadri; Fiscal Year: 2007
    ..cholerae. ..
  18. The eae Gene Cluster of Enteropathogenic E.coli
    Michael Donnenberg; Fiscal Year: 2007
    ..The significance of this work is that it will lead to a better understanding of how bacteria inject proteins into host cells and interfere with pathways that protect the cells from death and maintain barrier function. ..
  19. Metabolic and Nutritional Effects of ART in Children
    Meera Chhagan; Fiscal Year: 2009
    ..All data will be entered into Epi Info and will be analyzed using standard PC-based data analysis packages, including SAS and SPSS. ..
  20. ENHANCING MUCOSAL IMMUNE RESPONSES BY MICROENCAPSULATION
    Paul Offit; Fiscal Year: 2005
    ..The availability of microencapsulated virus provides a unique opportunity to understand the relationship between APC and protective mucosal immune responses. ..
  21. Socioeconomic and Ethnic Disparities in Adult Health
    Narayan Sastry; Fiscal Year: 2008
    ..L.A.FANS-2/Adult data will publicly released as quickly as possible once fieldwork is complete, to enable a wide range of researchers to conduct research. ..
  22. Biomarkers of Stress and Health for Los Angeles Children
    Narayan Sastry; Fiscal Year: 2008
    ..A.FANS data will provide an important new resource for a wide range of researchers to investigate the effects of social factors on children's stress, disease, and health. ..
  23. Breast milk: Physiology, Biochemistry and Outcomes
    Ardythe Morrow; Fiscal Year: 2006
    ..A list of these publications is found on our society's website (www.isrhml.org.umu.se). [unreadable] [unreadable] [unreadable]..
  24. Measurement of Gender Differences in Disability and Care
    Kathryn Yount; Fiscal Year: 2002
    ....
  25. COMMUNITY EFFECTS ON CHILD HEALTH
    Narayan Sastry; Fiscal Year: 2002
    ....
  26. ENDOTHELIAL GB3 SPECIES INVOLVED IN HUS PATHOGENESIS
    DAVID NEWBURG; Fiscal Year: 2003
    ..The detailed description of the expression of these endothelial cell Stx receptors will potentially lead to development of precisely targeted therapies that can reduce Stx toxicity and these devastating effects of HUS/TTP. ..
  27. Residential Mobility and Tracking of Adults
    Narayan Sastry; Fiscal Year: 2003
    ..Data from L.A.FANS-1 and ITS will also be used to investigate the determinants of individual residential mobility and migration among adults and the elderly and the determinants of residential turnover in Los Angeles neighborhoods. ..