postoperative complications

Summary

Summary: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Top Publications

  1. ncbi Transsphenoidal surgery for pituitary tumors in the United States, 1996-2000: mortality, morbidity, and the effects of hospital and surgeon volume
    Fred G Barker
    Brain Tumor Center, Neurosurgical Service, Departments of Surgery, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 88:4709-19. 2003
  2. ncbi Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
    Alexander T Cohen
    King s College Hospital, London, UK
    Lancet 371:387-94. 2008
  3. ncbi Multimodal strategies to improve surgical outcome
    Henrik Kehlet
    Department of Surgical Gastroenterology, Hvidovre University Hospital, Hvidovre, Denmark
    Am J Surg 183:630-41. 2002
  4. pmc Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey
    Daniel Dindo
    Department of Visceral and Transplantation Surgery, University Hospital of Zurich, Zurich, Switzerland
    Ann Surg 240:205-13. 2004
  5. ncbi Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    William H Geerts
    Thromboembolism Program, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Chest 133:381S-453S. 2008
  6. ncbi Postoperative pancreatic fistula: an international study group (ISGPF) definition
    Claudio Bassi
    Surgical and Gastroenterological Department, Hospital G B Rossi, University of Verona, Italy
    Surgery 138:8-13. 2005
  7. ncbi Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study
    Andrea Lassnigg
    Department of Cardiothoracic Anesthesia and Intensive Care Medicine, University Hospital of Vienna, Waehrihger Guertel 18 20, A 1090 Vienna, Austria
    J Am Soc Nephrol 15:1597-605. 2004
  8. ncbi Role of interleukin-1beta in postoperative cognitive dysfunction
    Mario Cibelli
    Department of Anesthetics, Pain Medicine, and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, United Kingdom
    Ann Neurol 68:360-8. 2010
  9. ncbi A randomized, controlled trial of surgery for temporal-lobe epilepsy
    S Wiebe
    Department of Clinical Neurological Sciences, University of Western Ontario, and London Health Sciences Centre, Canada
    N Engl J Med 345:311-8. 2001
  10. ncbi Predictors of cognitive dysfunction after major noncardiac surgery
    Terri G Monk
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, 27705, USA
    Anesthesiology 108:18-30. 2008

Research Grants

  1. FOCUS
    JEFFREY LEE CARSON; Fiscal Year: 2011
  2. The geriatric surgical patient: stress, anesthetics, and functional outcomes
    Stacie Deiner; Fiscal Year: 2012
  3. Effects of Physician Social Networks on Surgical Quality, Safety, and Costs
    John Malcolm Hollingsworth; Fiscal Year: 2013
  4. FOCUS Data Coordinating Center
    Michael L Terrin; Fiscal Year: 2010
  5. Surgical Treatment Outcomes for Patients with Psychiatric Disorders (STOPP)
    Laurel A Copeland; Fiscal Year: 2013
  6. Obesity in ovarian cancer prognosis
    Elisa V Bandera; Fiscal Year: 2012
  7. Decision Aid for Cigarette Smokers Undergoing Surgery
    David O Warner; Fiscal Year: 2012
  8. Frailty, Inflammation, and Psychological Well-being in Older Adults
    Rachel Roiland; Fiscal Year: 2011
  9. Adjustable balloon implant for medialization thyroplasty
    Matthew R Hoffman; Fiscal Year: 2012
  10. Pulmonary Rehabiltation before Lung Cancer Resection
    ROBERTO PABLO BENZO; Fiscal Year: 2013

Detail Information

Publications291 found, 100 shown here

  1. ncbi Transsphenoidal surgery for pituitary tumors in the United States, 1996-2000: mortality, morbidity, and the effects of hospital and surgeon volume
    Fred G Barker
    Brain Tumor Center, Neurosurgical Service, Departments of Surgery, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 88:4709-19. 2003
    ..9% at lowest-caseload-quartile hospitals and 0.4% at highest-volume-quartile hospitals. Postoperative complications (26.5% of admissions) were less frequent with higher-volume hospitals (P = 0.03) or surgeons (P = 0...
  2. ncbi Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
    Alexander T Cohen
    King s College Hospital, London, UK
    Lancet 371:387-94. 2008
    ....
  3. ncbi Multimodal strategies to improve surgical outcome
    Henrik Kehlet
    Department of Surgical Gastroenterology, Hvidovre University Hospital, Hvidovre, Denmark
    Am J Surg 183:630-41. 2002
    ..To evaluate the effect of modifying perioperative care in noncardiac surgical patients on morbidity, mortality, and other outcome measures...
  4. pmc Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey
    Daniel Dindo
    Department of Visceral and Transplantation Surgery, University Hospital of Zurich, Zurich, Switzerland
    Ann Surg 240:205-13. 2004
    ..assessment is gaining increasing attention, there is still no consensus on how to define and grade postoperative complications. This shortcoming hampers comparison of outcome data among different centers and therapies and over time...
  5. ncbi Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    William H Geerts
    Thromboembolism Program, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Chest 133:381S-453S. 2008
    ..We recommend that, on admission to the ICU, all patients be assessed for their risk of VTE, and that most receive thromboprophylaxis (Grade 1A)...
  6. ncbi Postoperative pancreatic fistula: an international study group (ISGPF) definition
    Claudio Bassi
    Surgical and Gastroenterological Department, Hospital G B Rossi, University of Verona, Italy
    Surgery 138:8-13. 2005
    ..Our aim was to agree upon an objective and internationally accepted definition to allow comparison of different surgical experiences...
  7. ncbi Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study
    Andrea Lassnigg
    Department of Cardiothoracic Anesthesia and Intensive Care Medicine, University Hospital of Vienna, Waehrihger Guertel 18 20, A 1090 Vienna, Austria
    J Am Soc Nephrol 15:1597-605. 2004
    ..for various established demographic preoperative risk indicators, intraoperative parameters, and postoperative complications. In the 2441 patients in whom serum creatinine decreased, early mortality was 2.6% in contrast to 8...
  8. ncbi Role of interleukin-1beta in postoperative cognitive dysfunction
    Mario Cibelli
    Department of Anesthetics, Pain Medicine, and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, United Kingdom
    Ann Neurol 68:360-8. 2010
    ..We explored whether systemic inflammation, in response to surgical trauma, triggers hippocampal inflammation and subsequent memory impairment, in a mouse model of orthopedic surgery...
  9. ncbi A randomized, controlled trial of surgery for temporal-lobe epilepsy
    S Wiebe
    Department of Clinical Neurological Sciences, University of Western Ontario, and London Health Sciences Centre, Canada
    N Engl J Med 345:311-8. 2001
    ..We conducted a randomized, controlled trial to assess the efficacy and safety of surgery for temporal-lobe epilepsy...
  10. ncbi Predictors of cognitive dysfunction after major noncardiac surgery
    Terri G Monk
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, 27705, USA
    Anesthesiology 108:18-30. 2008
    ....
  11. ncbi Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial
    Pierre J Guillou
    Academic Unit of Surgery, St James s University Hospital, Leeds, UK
    Lancet 365:1718-26. 2005
    ..We compared short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer to predict long-term outcomes...
  12. ncbi Long-term consequences of postoperative cognitive dysfunction
    Jacob Steinmetz
    Department of Anesthesia, Center of Head and Orthopedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Anesthesiology 110:548-55. 2009
    ..Postoperative cognitive dysfunction (POCD) is common in elderly patients after noncardiac surgery, but the consequences are unknown. The authors' aim was to determine the effects of POCD on long-term prognosis...
  13. pmc Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline
    Niccolò Terrando
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
    Proc Natl Acad Sci U S A 107:20518-22. 2010
    ..Taken together, our results suggest a unique therapeutic potential for preemptive treatment with anti-TNF antibody to prevent surgery-induced cognitive decline...
  14. ncbi World review of laparoscopic liver resection-2,804 patients
    Kevin Tri Nguyen
    Department of Surgery, UPMC Liver Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Ann Surg 250:831-41. 2009
    ..To provide a review of the world literature on laparoscopic liver resection...
  15. ncbi N-3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trial
    Leonardo Calo
    Department of Cardiac Diseases, San Filippo Neri Hospital, Rome, Italy
    J Am Coll Cardiol 45:1723-8. 2005
    ....
  16. pmc Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study
    J J W Roche
    Department of Trauma and Orthopaedics, University Hospital Nottingham, Nottingham, NG7 2UH
    BMJ 331:1374. 2005
    ..the association between these complications and mortality at 30 days and one year after surgery for hip fracture and to examine the association between preoperative comorbidity and the risk of postoperative complications and mortality.
  17. pmc Determinants of long-term survival after major surgery and the adverse effect of postoperative complications
    Shukri F Khuri
    Departments of Surgery, VA Boston Healthcare System, MA 02132, USA
    Ann Surg 242:326-41; discussion 341-3. 2005
    ..The objective of this study was to identify the determinants of 30-day postoperative mortality and long-term survival after major surgery as exemplified by 8 common operations...
  18. ncbi Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
    Bengt I Eriksson
    Department of Orthopaedic Surgery, Sahlgrenska University Hospital Ostra, Gothenburg, Sweden
    Lancet 370:949-56. 2007
    ..After hip replacement surgery, prophylaxis following discharge from hospital is recommended to reduce the risk of venous thromboembolism. Our aim was to assess the oral, direct thrombin inhibitor dabigatran etexilate for such prophylaxis...
  19. ncbi Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description
    Alain Cribier
    Department of Cardiology, Charles Nicolle Hospital, University of Rouen, Rouen, France
    Circulation 106:3006-8. 2002
    ..Valve replacement had been declined for this patient, and balloon valvuloplasty had been performed with nonsustained results...
  20. ncbi Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Recent advances in prevention and management
    T Liakakos
    3rd Academic Department of Surgery, University of Athens Medical School, Athens, Greece
    Dig Surg 18:260-73. 2001
    ....
  21. ncbi Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)
    Moritz N Wente
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany
    Surgery 142:761-8. 2007
    ..Several surgical centers use a different definition of DGE. Hence, a valid comparison of different study reports and operative techniques is not possible...
  22. pmc One thousand consecutive pancreaticoduodenectomies
    John L Cameron
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Ann Surg 244:10-5. 2006
    ..To trace the evolution of pancreaticoduodenectomy from the decade of the 1960s through the first decade of the new Millenium, through the experience of one surgeon doing 1000 consecutive operations...
  23. ncbi Off-pump or on-pump coronary-artery bypass grafting at 30 days
    Andre Lamy
    Population Health Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada
    N Engl J Med 366:1489-97. 2012
    ..The relative benefits and risks of performing coronary-artery bypass grafting (CABG) with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary bypass (on-pump CABG), are not clearly established...
  24. ncbi Continuous improvement of survival outcomes of resection of hepatocellular carcinoma: a 20-year experience
    Sheung Tat Fan
    State Key Laboratory for Liver Research, The University of Hong Kong, Pokfulam, Hong Kong
    Ann Surg 253:745-58. 2011
    ..To investigate the trend of the posthepatectomy survival outcomes of hepatocellular carcinoma (HCC) patients by analysis of a prospective cohort of 1198 patients over a 20-year period...
  25. ncbi Evidence-based surgical care and the evolution of fast-track surgery
    Henrik Kehlet
    Section of Surgical Pathophysiology 4074, Rigshospitalet, Copenhagen, Denmark
    Ann Surg 248:189-98. 2008
    ..Optimization of postoperative outcome requires the application of evidence-based principles of care carefully integrated into a multimodal rehabilitation program...
  26. ncbi Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1000 cases
    Ryosuke Tateishi
    Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    Cancer 103:1201-9. 2005
    ..Previously reported treatment efficacy and complication rates have varied considerably...
  27. ncbi Descemet's stripping endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology
    W Barry Lee
    Eye Consultants of Atlanta, 3225 Cumberland Boulevard, Atlanta, GA 30339, USA
    Ophthalmology 116:1818-30. 2009
    ..To review the published literature on safety and outcomes of Descemet's stripping endothelial keratoplasty (DSEK) for the surgical treatment of endothelial diseases of the cornea...
  28. ncbi Does treatment with n-3 polyunsaturated fatty acids prevent atrial fibrillation after open heart surgery?
    Ragnhildur Heidarsdottir
    Department of Physiology, School of Health Sciences, University of Iceland, Reykjavik, Iceland
    Europace 12:356-63. 2010
    ..To examine the effect of n-3 polyunsaturated fatty acid (PUFA) treatment on the incidence of post-operative atrial fibrillation (POAF)...
  29. ncbi A comparison of on-pump and off-pump coronary bypass surgery in low-risk patients
    Hendrik M Nathoe
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    N Engl J Med 348:394-402. 2003
    ....
  30. ncbi Video-assisted thoracic surgery lobectomy: experience with 1,100 cases
    Robert J McKenna
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Ann Thorac Surg 81:421-5; discussion 425-6. 2006
    ..This series is reviewed to assess these issues...
  31. ncbi Hernias: inguinal and incisional
    Andrew Kingsnorth
    Derriford Hospital, Level 7, Plymouth, UK
    Lancet 362:1561-71. 2003
    ..Many of the principles of management apply equally to inguinal and incisional hernias. We recommend that the more difficult and complex of the procedures be referred to specialists...
  32. ncbi A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia
    A E van Harten
    Department of Anesthesiology, University Medical Centre Groningen, University of Groningen, The Netherlands
    Anaesthesia 67:280-93. 2012
    ....
  33. ncbi Iliac crest bone graft harvest donor site morbidity. A statistical evaluation
    J C Banwart
    Section of Orthopedic Surgery, University of Kansas Medical Center, Kansas City, USA
    Spine (Phila Pa 1976) 20:1055-60. 1995
    ..The findings suggest that procedural refinements of limiting subcutaneous dissection and providing layered tension-free incision closure may improve results...
  34. ncbi Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice
    Wouter J de Jonge
    Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Gastroenterology 125:1137-47. 2003
    ..We aimed to study its pathophysiology in a murine model by determining gastric emptying after manipulation of the small intestine...
  35. ncbi Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats
    Hui Juan He
    Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China
    CNS Neurosci Ther 18:994-1002. 2012
    ..Herein, we sought to determine the relationship between cognitive decline, blood-brain barrier (BBB) permeability, and inflammation, namely high mobility group box-1 (HMGB1), after surgery in aged rats...
  36. ncbi Total arch replacement combined with stented elephant trunk implantation: a new "standard" therapy for type a dissection involving repair of the aortic arch?
    Lizhong Sun
    Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing 100029, China
    Circulation 123:971-8. 2011
    ..We retrospectively reviewed our experience with aortic arch replacement for type A dissection involving the arch...
  37. ncbi Immunosuppression following surgical and traumatic injury
    Fumio Kimura
    Department of General Surgery, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Surg Today 40:793-808. 2010
    ..Recent basic and clinical studies have elucidated the functional effects of surgical and traumatic injury on the immune system. The research studies of interest may in future aid in the selection of appropriate therapeutic protocols...
  38. ncbi Surgery of colorectal cancer: surgical morbidity and five- and ten-year results in 2400 patients--monoinstitutional experience
    Ludger Staib
    Department of General and Visceral Surgery, University of Ulm, Steinhovelstrasse 9, 89070 Ulm Donau, Germany
    World J Surg 26:59-66. 2002
    ..The morbidity and mortality were low and were not increased by multivisceral resections...
  39. ncbi Variation in hospital mortality associated with inpatient surgery
    Amir A Ghaferi
    Michigan Surgical Collaborative for Outcomes Research and Evaluation, The Department of Surgery, University of Michigan, Ann Arbor 48104, USA
    N Engl J Med 361:1368-75. 2009
    Hospital mortality that is associated with inpatient surgery varies widely. Reducing rates of postoperative complications, the current focus of payers and regulators, may be one approach to reducing mortality...
  40. pmc Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia
    Jacobus W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Surg 240:578-83; discussion 583-5. 2004
    ..The objective of this study was to determine the best treatment of incisional hernia, taking into account recurrence, complications, discomfort, cosmetic result, and patient satisfaction...
  41. ncbi Postoperative mortality and morbidity in French patients undergoing colorectal surgery: results of a prospective multicenter study
    Arnaud Alves
    Department of Digestive Surgery, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    Arch Surg 140:278-83, discussion 284. 2005
    ..Better knowledge of independent risk factors might decrease mortality and morbidity rates following colorectal surgery...
  42. ncbi Preoperative n-3 polyunsatured fatty acids are associated with a decrease in the incidence of early atrial fibrillation following cardiac surgery
    Giovanni Mariscalco
    Department of Surgical Sciences, Cardiac Surgery Unit, Varese University Hospital, University of Insubria, Varese, Italy
    Angiology 61:643-50. 2010
    ..We investigated whether preoperative PUFA therapy is effective in reducing AF after cardiac surgery during the surgical hospitalization and/or the cardiac rehabilitation period...
  43. pmc Effects of clinical pathways in the joint replacement: a meta-analysis
    A Barbieri
    Department of Clinical and Experimental Medicine, University of Eastern Piedmont A, Avogadro, Novara, Italy
    BMC Med 7:32. 2009
    ..of clinical pathways was evaluated assessing the major outcomes of in-hospital hip and knee joint replacement processes: postoperative complications, number of patients discharged at home, length of in-hospital stay and direct costs.
  44. pmc Laparoscopic liver resections: a feasibility study in 30 patients
    D Cherqui
    Departments of General and Digestive Surgery and Anesthesiology, H opital Henri Mondor Université Paris XII, Creteil, France
    Ann Surg 232:753-62. 2000
    ..To assess the feasibility and safety of laparoscopic liver resections...
  45. ncbi Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus
    Yanjie Wan
    Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London
    Anesthesiology 106:436-43. 2007
    ..The authors investigated the role of cytokine-mediated inflammation within the central nervous system in the development of cognitive dysfunction in a rat model...
  46. pmc Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA
    Am J Ophthalmol 153:804-814.e1. 2012
    To describe postoperative complications encountered in the Tube Versus Trabeculectomy (TVT) Study during 5 years of follow-up.
  47. ncbi Self-expanding metal stents for gastroduodenal malignancies: systematic review of their clinical effectiveness
    A Dormann
    Dept of Medicine, Minden Hospital, Minden, Germany
    Endoscopy 36:543-50. 2004
    ..Recently, metal stents have emerged as a new therapeutic option. The aim of the present study was to review the currently published evidence on the effectiveness and safety of this form of endoscopic treatment...
  48. ncbi A surgical safety checklist to reduce morbidity and mortality in a global population
    Alex B Haynes
    Harvard School of Public Health, Massachusetts General Hospital, Boston, USA
    N Engl J Med 360:491-9. 2009
    ..We hypothesized that a program to implement a 19-item surgical safety checklist designed to improve team communication and consistency of care would reduce complications and deaths associated with surgery...
  49. ncbi Comparison of long-term prognosis of laparoscopy-assisted gastrectomy and conventional open gastrectomy with special reference to D2 lymph node dissection
    Hirohiko Sato
    Department of Surgery, Institute of Health Biosciences, The University of Tokushima, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Surg Endosc 26:2240-6. 2012
    ..This study assessed short- and long-term outcomes after LAG with lymph node dissection in early and advanced gastric cancer...
  50. ncbi Early enteral nutrition reduces the rate of life-threatening complications after thoracic esophagectomy in patients with esophageal cancer
    T Fujita
    Division of Esophageal Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Eur Surg Res 48:79-84. 2012
    ..However, whether enteral nutrition decreases rates of surgical complications and increases the completion rate of the clinical management pathway is unclear...
  51. ncbi Perioperative nutrition in malnourished surgical cancer patients - a prospective, randomized, controlled clinical trial
    Stanislaw Klek
    Stanley Dudrick s Memorial Hospital, General Surgery Unit, 15 Tyniecka Street, 32 050 Skawina, Poland
    Clin Nutr 30:708-13. 2011
    ..The aim of the study was to evaluate the clinical value of the route and type of perioperative nutritional support...
  52. ncbi Aprotinin during coronary-artery bypass grafting and risk of death
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    N Engl J Med 358:771-83. 2008
    ..Aprotinin (Trasylol) is used to mitigate bleeding during coronary-artery bypass grafting (CABG). Accumulating evidence suggests that this practice increases mortality...
  53. ncbi Immunonutrition in gastrointestinal surgery
    Y Cerantola
    Department of Visceral Surgery, University Hospital Vaudois CHUV, Bugnon 46, 1011 Lausanne, Switzerland
    Br J Surg 98:37-48. 2011
    ..The use of immunonutrition (IN) in such patients is not widespread because the available data are heterogeneous, and some show contradictory results with regard to complications, mortality and length of hospital stay...
  54. ncbi Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients
    Jong Ju Jeong
    Department of Surgery, Yonsei University College of Medicine, Seodaemun gu, Seoul, South Korea
    J Surg Oncol 100:477-80. 2009
    ..The aim of this study was to evaluate and compare the early surgical outcomes of endoscopic and conventional open thyroidectomies in patients with papillary thyroid microcarcinoma (PTMC)...
  55. ncbi Laparoscopic vs open hepatic resection: a comparative study
    M Morino
    Second Department of General Surgery, University of Turin, C so A M Dogliotti 14, 10126 Turin, Italy
    Surg Endosc 17:1914-8. 2003
    ..Although the feasibility of minor laparoscopic liver resections (LLR) has been demonstrated, data comparing the open vs the laparoscopic approach to liver resection are lacking...
  56. ncbi Perioperative immunonutrition for gastrointestinal cancer: a systematic review of randomized controlled trials
    Yan Zhang
    Gansu Provincial Hospital, Donggang West Road No 204, Chengguan District, Lanzhou City, Gansu Province, China
    Surg Oncol 21:e87-95. 2012
    ..To improve the clinical outcome, immunonutrition (IN) was usually used in the patients undergoing elective gastrointestinal caner surgery. However, its effectiveness remains uncertain...
  57. ncbi Fewer adhesions induced by laparoscopic surgery?
    C N Gutt
    Department of General, Visceral and Trauma Surgery, Ruprecht Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
    Surg Endosc 18:898-906. 2004
    ..Laparoscopic surgery has potential theoretical advantages over open surgery in reducing the rate of adhesion formation, but very few comparative studies are available to prove this...
  58. ncbi Extraction of impacted mandibular third molars: postoperative complications and their risk factors
    Francois Blondeau
    Affiliated medical centre of the Enfant Jésus Hospital, Quebec City, Quebec, Canada
    J Can Dent Assoc 73:325. 2007
    ..The relation between these 3 complications and several clinical variables (age, sex, degree of impaction, surgical difficulty and use of oral contraceptives) was also examined...
  59. ncbi Chronic low back pain and fusion: a comparison of three surgical techniques: a prospective multicenter randomized study from the Swedish lumbar spine study group
    Peter Fritzell
    Department of Orthopedic Surgery, Falun Hospital, Falun, Sweden
    Spine (Phila Pa 1976) 27:1131-41. 2002
    ..A multicenter randomized study with a 2-year follow-up period and an independent observer was conducted...
  60. ncbi Positioning of total knee arthroplasty with and without navigation support. A prospective, randomised study
    M Sparmann
    Orthopaedic Department, Immanuel Hospital, Free University of Berlin, Berlin, Germany
    J Bone Joint Surg Br 85:830-5. 2003
    ..0001). The use of a navigation system was therefore shown to improve the alignment of the implant...
  61. ncbi D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer
    Mitsuru Sasako
    Gastric Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    N Engl J Med 359:453-62. 2008
    ..We conducted a randomized, controlled trial at 24 hospitals in Japan to compare D2 lymphadenectomy alone with D2 lymphadenectomy plus PAND in patients undergoing gastrectomy for curable gastric cancer...
  62. pmc Laparoscopic repair of ventral hernias: nine years' experience with 850 consecutive hernias
    B Todd Heniford
    Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
    Ann Surg 238:391-9; discussion 399-400. 2003
    ..To evaluate the efficacy and safety of laparoscopic repair of ventral hernias...
  63. ncbi Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study
    Kees J Kalisvaart
    Department of Geriatric Medicine, Medical Center Alkmaar, Alkmaar, The Netherlands
    J Am Geriatr Soc 53:1658-66. 2005
    ..To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium...
  64. pmc Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery
    M V Podgoreanu
    Department of Anesthesiology, Box 3094, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 114:I275-81. 2006
    ..We tested the hypothesis that candidate gene polymorphisms in inflammatory pathways contribute to risk of PMI after cardiac surgery...
  65. ncbi Comorbidity in older surgical cancer patients: influence on patient care and outcome
    Maryska L G Janssen-Heijnen
    Eindhoven Cancer Registry, Comprehensive Cancer Centre South, P O Box 231, 5600 AE Eindhoven, Eindhoven, The Netherlands
    Eur J Cancer 43:2179-93. 2007
    ..Prospective randomised studies are needed for refining selection criteria for surgery in elderly cancer patients and for anticipation and prevention of complications...
  66. ncbi Short-term outcomes of the Australasian randomized clinical study comparing laparoscopic and conventional open surgical treatments for colon cancer: the ALCCaS trial
    Peter J Hewett
    Division of Surgery, The Queen Elizabeth Hospital, Woodville South, Australia
    Ann Surg 248:728-38. 2008
    ..The long-term outcomes of all international randomized controlled trials are still awaited, and short-term outcomes are important in the interim...
  67. ncbi Early enteral nutrition in acutely ill patients: a systematic review
    P E Marik
    Critical Care Medicine, The Mercy Hospital of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 29:2264-70. 2001
    ..The results of this meta-analysis must, however, be interpreted with some caution because of the significant heterogeneity between studies...
  68. ncbi Prospective randomized controlled trial of an intramedullary nail versus dynamic screw and plate for intertrochanteric fractures of the femur
    C I Adams
    The Orthopaedic Trauma Unit, The Royal Infirmary of Edinburgh, Scotland
    J Orthop Trauma 15:394-400. 2001
    ..37; odds ratio, 2.29 [0.6-9.0]). The development of other postoperative complications was the same in both groups...
  69. ncbi Should immunonutrition become routine in critically ill patients? A systematic review of the evidence
    D K Heyland
    Angada 3, Kingston General Hospital, 76 Stuart St, Kingston, Ontario K7L 2V7, Canada
    JAMA 286:944-53. 2001
    ..Several nutrients have been shown to influence immunologic and inflammatory responses in humans. Whether these effects translate into an improvement in clinical outcomes in critically ill patients remains unclear...
  70. ncbi Complications, failure to rescue, and mortality with major inpatient surgery in medicare patients
    Amir A Ghaferi
    Department of Surgery, Michigan Surgical Collaborative for Outcomes Research and Evaluation M SCORE, University of Michigan, Ann Arbor, MI 48104, USA
    Ann Surg 250:1029-34. 2009
    ..We sought to determine whether hospital variations in surgical mortality were due to differences in complication rates or failure to rescue rates (ie, case-fatality rates in patients with a complication)...
  71. ncbi Acute kidney injury after cardiac surgery: focus on modifiable risk factors
    Keyvan Karkouti
    Department of Anesthesia and Health Policy, Management, and Evaluation, Toronto General Hospital, University of Toronto, 200 Elizabeth St, EN 3 402, Toronto, Ontario, Canada M5G 2C4
    Circulation 119:495-502. 2009
    ..Lacking effective therapies, risk factor modification may offer a means of preventing this complication. The objective of the present study was to identify and determine the prognostic importance of such risk factors...
  72. ncbi Development and validation of an acute kidney injury risk index for patients undergoing general surgery: results from a national data set
    Sachin Kheterpal
    Department of Anesthesiology, University of Michigan Medical School, USA
    Anesthesiology 110:505-15. 2009
    ..The authors sought to identify the incidence, risk factors, and mortality impact of acute kidney injury (AKI) after general surgery using a large and representative national clinical data set...
  73. ncbi Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Lancet 359:1812-8. 2002
    ..We aimed to determine the effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection in human beings...
  74. ncbi ESPEN Guidelines on Parenteral Nutrition: surgery
    M Braga
    Department of Surgery, San Raffaele University, Milan, Italy
    Clin Nutr 28:378-86. 2009
    ..In those patients who are unable to be fed via the enteral route after surgery, and in whom total or near total parenteral nutrition is required, a full range of vitamins and trace elements should be supplemented on a daily basis...
  75. ncbi Percutaneous compression plating versus compression hip screw fixation for the treatment of intertrochanteric hip fractures
    Amos Peyser
    Department of Orthopaedic Surgery, Hadassah Hebrew University Medical Centre, P O Box 12000, Jerusalem 91120, Israel
    Injury 36:1343-9. 2005
    ..01). The rate of systemic postoperative complications was lower in the PCCP group (p=0.02) both in univariate and multivariate analyses...
  76. ncbi Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma
    M Wagner
    Department of Visceral and Transplantation Surgery, University of Berne, Berne, Switzerland
    Br J Surg 91:586-94. 2004
    ..This prospective study evaluated risk factors for survival after resection for pancreatic adenocarcinoma...
  77. ncbi Extended lymph node dissection for gastric cancer: who may benefit? Final results of the randomized Dutch gastric cancer group trial
    H H Hartgrink
    Department of Surgery, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Oncol 22:2069-77. 2004
    ..We have reviewed the results of our trial after follow-up of more than 10 years...
  78. ncbi Postoperative complications in patients with obstructive sleep apnea
    Roop Kaw
    Department of Hospital Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Chest 141:436-41. 2012
    ..Unrecognized obstructive sleep apnea (OSA) is associated with unfavorable perio-perative outcomes among patients undergoing noncardiac surgery (NCS)...
  79. pmc Postoperative delirium and cognitive dysfunction
    S Deiner
    Department of Anesthesiology, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Br J Anaesth 103:i41-46. 2009
    ....
  80. ncbi Postoperative complications associated with 25-gauge pars plana vitrectomy
    Omesh P I Gupta
    Retina Service, Wills Eye at Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmic Surg Lasers Imaging 38:270-5. 2007
    To report postoperative complications in eyes undergoing 25-gauge pars plana vitrectomy (PPV).
  81. ncbi The adult scoliosis
    Max Aebi
    Institute for Evaluative Research in Orthopaedic Surgery, University of Bern, Bern, Switzerland
    Eur Spine J 14:925-48. 2005
    ....
  82. pmc Alcohol screening and risk of postoperative complications in male VA patients undergoing major non-cardiac surgery
    Katharine A Bradley
    Health Services Research and Development, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA 98101, USA
    J Gen Intern Med 26:162-9. 2011
    ..Four weeks of preoperative abstinence decreases the risk of complications, but practical approaches for early preoperative identification of alcohol misuse are needed...
  83. ncbi Impact of surgeon experience and buttress material on postoperative complications after laparoscopic sleeve gastrectomy
    Markos Daskalakis
    Center for Minimal Invasive Surgery, Department of General and Bariatric Surgery, Krankenhaus Sachsenhausen, Frankfurt am Main, Germany
    Surg Endosc 25:88-97. 2011
    ..Sleeve gastrectomy is gaining popularity whether as a primary, staged or revisional operation. The aim of this study is to evaluate the perioperative safety and the learning curve for laparoscopic sleeve gastrectomy (LSG)...
  84. ncbi Excess costs attributable to postoperative complications
    Kathleen Carey
    VA Center for Health Quality, Outcomes and Economic Research
    Med Care Res Rev 68:490-503. 2011
    This article estimates excess costs associated with postoperative complications among inpatients treated in Veterans Health Administration (VA) hospitals...
  85. ncbi Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial
    Markus K Diener
    Study Centre of the German Surgical Society and Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
    Lancet 377:1514-22. 2011
    ..We postulated that standardised closure with a stapler device would prevent pancreatic fistula more effectively than would a hand-sewn closure of the remnant...
  86. ncbi Risk factors for 30-day postoperative complications and mortality after below-knee amputation: a study of 2,911 patients from the national surgical quality improvement program
    Philip J Belmont
    Department of Orthopaedic Surgery, William Beaumont Army Medical Center, Texas Tech University Health Sciences Center, El Paso, TX 79920, USA
    J Am Coll Surg 213:370-8. 2011
    ..This investigation sought to evaluate risk factors for morbidity and mortality from a large series of below-knee amputees prospectively entered in a national database...
  87. ncbi Complications of thyroid surgery: analysis of a multicentric study on 14,934 patients operated on in Italy over 5 years
    Lodovico Rosato
    Department of Surgery, Endocrine Surgical Unit, Ivrea Hospital, Piazza della Credenza, 2 10015 Ivrea, Italy
    World J Surg 28:271-6. 2004
    ....
  88. pmc Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study
    Jean Francois Gigot
    Saint Luc University Hospital, Brussels, Belgium
    Ann Surg 236:90-7. 2002
    ..To assess the feasibility, safety, and outcome of laparoscopic liver resection for malignant liver tumors...
  89. pmc Robot-assisted partial nephrectomy: a large single-institutional experience
    Benjamin J Scoll
    Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Urology 75:1328-34. 2010
    ..The robotic surgical system may enable faster and greater technical proficiency, facilitating a minimally invasive approach to more difficult lesions while reducing ischemia time...
  90. ncbi Computer-assisted knee arthroplasty versus a conventional jig-based technique. A randomised, prospective trial
    S K Chauhan
    Royal Perth Hospital, Perth, Western Australia
    J Bone Joint Surg Br 86:372-7. 2004
    ..011) and femorotibial mismatch (p = 0.037). Standing alignment was also improved (p = 0.004) and blood loss was less (p = 0.0001). Computer-assisted surgery took longer with a mean increase of 13 minutes (p = 0.0001)...
  91. ncbi Influence of major postoperative complications on health-related quality of life among long-term survivors of esophageal cancer surgery
    Maryam Derogar
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    J Clin Oncol 30:1615-9. 2012
    To evaluate the effect of major postoperative complications on health-related quality of life (HRQL) in 5-year survivors of esophageal cancer surgery.
  92. ncbi Elastic stable intramedullary nailing versus nonoperative treatment of displaced midshaft clavicular fractures-a randomized, controlled, clinical trial
    Vinzenz Smekal
    From the Department of Trauma Surgery and Sports Medicine, Innsbruck Medical University, Innsbruck, Austria
    J Orthop Trauma 23:106-12. 2009
    ..To compare elastic stable intramedullary nailing (ESIN) with nonoperative treatment of fully displaced midshaft clavicular fractures in adults...
  93. ncbi Supply of pre- and probiotics reduces bacterial infection rates after liver transplantation--a randomized, double-blind trial
    Nada Rayes
    Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Humboldt University, Berlin, Germany
    Am J Transplant 5:125-30. 2005
    ..Early enteral nutrition supplemented with a mixture of LAB and fibers reduces bacterial infection rates following liver transplantation. Treatment with only fibers led to a low incidence of severe infections...
  94. ncbi Cardiopulmonary exercise testing as a screening test for perioperative management of major surgery in the elderly
    P Older
    Western Hospital, Footscray, Victoria, Australia
    Chest 116:355-62. 1999
    ..To develop an integrated strategy for the identification and subsequent management of high-risk patients in order to reduce both morbidity and mortality...
  95. ncbi Gender differences in human sepsis
    J Schroder
    Department of General and Thoracic Surgery, University of Kiel, Germany
    Arch Surg 133:1200-5. 1998
    ..In animal studies, gender differences were related to hormonal and immunologic changes that were associated with an increased susceptibility to sepsis in males...
  96. ncbi Quantitative weighting of postoperative complications based on the accordion severity grading system: demonstration of potential impact using the american college of surgeons national surgical quality improvement program
    Matthew R Porembka
    Department of Surgery, School of Medicine, Washington University in St Louis, St Louis, MO, USA
    J Am Coll Surg 210:286-98. 2010
    To quantify severity of postoperative complications based on the Accordion Severity Grading System, determine the ability of severity grading to enhance National Surgical Quality Improvement Program (NSQIP) data, and develop an aggregate ..
  97. ncbi The impact of pre-operative education on recovery following coronary artery bypass surgery. A randomized controlled clinical trial
    C M Shuldham
    Royal Brompton and Harefield Trust, London, U K
    Eur Heart J 23:666-74. 2002
    ....
  98. ncbi Single incision laparoscopic cholecystectomy (SILC) versus laparoscopic cholecystectomy (LC)-a matched pair analysis
    Odo Gangl
    Department of Surgery, Krankenhaus der Elisabethinen, Fadingerstrasse 1, 4020 Linz, Austria
    Langenbecks Arch Surg 396:819-24. 2011
    ....
  99. ncbi United States Food and Drug Administration clinical trial of the Implantable Collamer Lens (ICL) for moderate to high myopia: three-year follow-up
    Donald R Sanders
    Center for Clinical Research, Chicago, Illinois, USA
    Ophthalmology 111:1683-92. 2004
    ..To report on 3-year postoperative safety and efficacy outcomes with the Myopic Implantable Collamer Lens (ICL)...
  100. ncbi [Surgery for morbid obesity: 2. Complications. Results of a Technologic Evaluation by the ANAES]
    S Msika
    Service de Chirurgie Generale et Digestive, Hopital Louis Mourier Colombes
    J Chir (Paris) 140:4-21. 2003
    ..Even the less traumatic surgical approach of laparoscopic band placement should not be considered free of risk; strict adherence to pre-operative surgical indications should be maintained...
  101. ncbi Complications of lateral plating in the minimally invasive lateral transpsoas approach
    Tien V Le
    Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida 33606, USA
    J Neurosurg Spine 16:302-7. 2012
    ..Three cases of hardware failure and 3 cases of vertebral body (VB) fractures associated with lateral plate placement are reported. The authors also review the literature pertaining to lateral plates and related complications...

Research Grants64

  1. FOCUS
    JEFFREY LEE CARSON; Fiscal Year: 2011
    ..human assistance at 60-days post-randomization), long-term survival, nursing home placement, and postoperative complications (death in hospital or within 30 days, pneumonia, myocardial infarction, thromboembolism, stroke, ..
  2. The geriatric surgical patient: stress, anesthetics, and functional outcomes
    Stacie Deiner; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Older age (>70) is an independent risk factor for postoperative complications and mortality. However the nature of age's contribution to postsurgical complications remains unclear...
  3. Effects of Physician Social Networks on Surgical Quality, Safety, and Costs
    John Malcolm Hollingsworth; Fiscal Year: 2013
    ..e., operative mortality, readmissions, and postoperative complications) and local network properties across 3 phases of the surgical episode...
  4. FOCUS Data Coordinating Center
    Michael L Terrin; Fiscal Year: 2010
    ..human assistance at 60-days post-randomization), long-term survival, nursing home placement, and postoperative complications (death in hospital or within 30 days, pneumonia, myocardial infarction, thromboembolism, stroke)...
  5. Surgical Treatment Outcomes for Patients with Psychiatric Disorders (STOPP)
    Laurel A Copeland; Fiscal Year: 2013
    ..3) Assess 30-day, 90-day, and 1-year postoperative complications (e.g...
  6. Obesity in ovarian cancer prognosis
    Elisa V Bandera; Fiscal Year: 2012
    ..Obesity in particular may delay diagnosis, hinder optimal surgical and cytotoxic treatment, and cause postoperative complications. Kaiser Permanente Northern California (KPNC) offers a unique opportunity to evaluate the impact of ..
  7. Decision Aid for Cigarette Smokers Undergoing Surgery
    David O Warner; Fiscal Year: 2012
    ..For those requiring elective surgery, even brief perioperative abstinence reduces immediate postoperative complications;the additional benefit to long-term health of permanent abstinence is clear...
  8. Frailty, Inflammation, and Psychological Well-being in Older Adults
    Rachel Roiland; Fiscal Year: 2011
    ..older adults for mortality, hospitalization, falls, worsening disability, nursing home admission, postoperative complications, depression, and fractures...
  9. Adjustable balloon implant for medialization thyroplasty
    Matthew R Hoffman; Fiscal Year: 2012
    ..b>Postoperative complications such as penetration and breathy phonation due to hypoadduction or dyspnea and pressed phonation due to ..
  10. Pulmonary Rehabiltation before Lung Cancer Resection
    ROBERTO PABLO BENZO; Fiscal Year: 2013
    ..of customized preoperative Pulmonary Rehabilitation on length of hospital stay and on the number of postoperative complications in patients that undergo a lung cancer resection and have severe COPD compared to a matched control ..
  11. Risk Prediction and Mechanistic Evaluation of Postoperative Acute Lung Injury
    Daryl J Kor; Fiscal Year: 2013
    ..ALI, and 2) to develop effective strategies to prevent postoperative ALI, one of the most significant postoperative complications today...
  12. Aminocaproic Acid and Bleeding in Spinal Surgery
    Sean Berenholtz; Fiscal Year: 2006
    ..association between anincreased number of allogeneic transfusions and an increased incidence of postoperative complications, including nosocomial infections, ICU length of stay, and hospital costs. 3...
  13. MICROCIRCULATORY PROTECTION IN LATE PRECONDITIONING
    Wei Wang; Fiscal Year: 2001
    ..It can result in microvascular damage leading to significant postoperative complications including muscle dysfunction and necrosis...
  14. Portable, In-Home Assessment of Pediatric Sleep Apnea
    DANIEL LEVENDOWSKI; Fiscal Year: 2006
    ..Accurate assessment of the severity of pediatric OSA is also required to identify children at risk for postoperative complications following tonsillectomy and adenoidectomy, the most common treatment for childhood OSA...
  15. Volume-Outcomes in Incontinence Surgery
    Jennifer Anger; Fiscal Year: 2005
    ..The primary outcome will be re-operation rates, repeat sling procedures (for failures), and other postoperative complications, stratified by high and low volume surgeons and hospitals.
  16. PEPTIDE ENHANCED ARTIFICIAL SKIN
    FREDERICK CAHN; Fiscal Year: 1999
    ..The weaknesses include a higher incidence of postoperative complications than for conventional autograft...
  17. ShoulderNav: Computer Assisted Total Shoulder Arthroplasty
    Constantinos Nikou; Fiscal Year: 2007
    ..to accurately plan and execute implantation of the prosthetic shoulder socket, thereby improving effectiveness of the prosthesis and lowering the risk of postoperative complications. [unreadable] [unreadable] [unreadable] [unreadable]
  18. ULTRASOUND AND NERVE STIMULATOR GUIDE
    LAWRENCE BUSSE; Fiscal Year: 1999
    ..only light sedation to accompany the regional blockade and thereby results in a low incidence of postoperative complications. In spite of its advantages, only 5-20% of patients eligible for RA receives this technique...
  19. ULTRASOUND AND NERVE STIMULATOR GUIDE
    LAWRENCE BUSSE; Fiscal Year: 2002
    ..benefits to patients since it requires only light sedation and thereby results in a low incidence of postoperative complications. Despite these advantages, only 5-20 percent of eligible patients receives RA...
  20. SEVERE DEPRESSION IN WOMEN AFTER CARDIAC SURGERY
    Lynn Doering; Fiscal Year: 2002
    ..The first objective is to obtain evidence regarding the risk of postoperative complications associated with compromised immune function in depressed women compared to non-depressed women ..
  21. Complications of Surgery for Spinal Stenosis: A Clinical Prediction Rule
    Richard A Deyo; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: A new method for estimating surgical risk will improve patient safety and assist in surgical decision-making, informed consent, monitoring surgical products, &improving quality assessment. ..
  22. Potential mechanism(s) of impaired pulsatile insulin secretion and action in Type
    ALEKSEY MATVEYENKO; Fiscal Year: 2008
    ..Specific Aim 3 will be undertaken with the additional guidance of Dr. Morris White at the Howard Hughes Medical Institute. [unreadable] [unreadable] [unreadable]..
  23. Acupuncture to aid post-colectomy recovery in colorectal cancer patients
    Gary Deng; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  24. Targeting Bone Remodeling For the Treatment of Osteoporosis
    John Bilezikian; Fiscal Year: 2008
    ..The purpose of this meeting is to bring together experts from these interdisciplinary fields so as to define the direction of the future. ..
  25. Effect of exendin-(9-39) on glucose metabolism in subjects with hyperinsulinism
    DIVA DE LEON; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  26. Role of GLP-1 in disorders of carbohydrate metabolism in children
    DIVA DE LEON; Fiscal Year: 2008
    ....
  27. Adenosine Signaling and Priapsim
    Yang Xia; Fiscal Year: 2008
    ..By understanding the molecular events involved in the development of priapism, we seek to develop novel therapeutic strategies to treat this disease. [unreadable] [unreadable] [unreadable]..
  28. Caregiver-based Intervention for Persistent Delirium
    Edward Marcantonio; Fiscal Year: 2007
    ..If promising, our findings will serve as pilot data for a definitive trial to test this novel strategy to improve the health of a vulnerable population of elders and their caregivers. [unreadable] [unreadable] [unreadable]..
  29. Discharge Planning and Telehealth for Post CABG Elders
    Ruth Kleinpell; Fiscal Year: 2009
    ..of the outcomes of nursing interventions for elderly cardiac surgery patients at high risk for developing postoperative complications and explore the effect of the DICE intervention on improving elders'outcomes post CABG.
  30. Fostering Independence in Nursing and Outcomes Research
    Christopher Friese; Fiscal Year: 2009
    ..The research projects examine the relationship between the nursing practice environment and outcomes of care for patients with cancer. ..
  31. Vessel Remodeling During Ductus Arteriosus Closure
    Ronald I Clyman; Fiscal Year: 2010
    ..These studies should increase our understanding of the mechanisms that prevent the preterm DA from closing and remodeling after birth. ..
  32. Structure, Process and Outcomes in Cancer Surgery
    John D Birkmeyer; Fiscal Year: 2010
    ..We will then identify the resources and processes of care that account for differences in hospital outcomes, with the ultimate goal of identifying best practices and improving care in all settings. ..
  33. Human Bladder Urothelial Cell Structure and Function in Bladder Hypersensation
    Toby C Chai; Fiscal Year: 2010
    ..By accomplishing these aims, we hope to develop an understanding of the pathogenesis of hypersensory bladder conditions which ultimately can lead to targeted treatment options. ..
  34. Epidemilogy of Parkinsonism in Welders
    Brad A Racette; Fiscal Year: 2011
    ..The cohort assembled will provide unique opportunities for future research projects into gene-environment interactions and exposure related neuroimaging changes. ..
  35. BENEFITS OF REGIONALIZING SURGERY FOR MEDICARE PATIENTS
    John Birkmeyer; Fiscal Year: 2002
    ..The investigators will then estimate the change in mortality, by assuming that the patient will acquire the average predicted mortality for a similar patient at the larger volume hospital. ..
  36. Enteral vs. IV Feeding: Effect on Mucosal Immunity
    Kenneth A Kudsk; Fiscal Year: 2010
    ....
  37. Donepezil-enhanced management of delirium in aged hip fracture patients
    Edward Marcantonio; Fiscal Year: 2007
    ..This study is the first in the PI's long-term goal to better understand the pathophysiological mechanisms of delirium and to develop and test therapies targeted to address these mechanisms. [unreadable] [unreadable] [unreadable]..
  38. Osteoarthritis following ACL reconstruction
    Braden Fleming; Fiscal Year: 2007
    ..abstract_text> ..
  39. Effects of Stretch on IC and Normal Urothelia
    Toby Chai; Fiscal Year: 2005
    ..ATP may mediate nociception in the bladder. Urothelial stretch thus appears to be an important consideration in diagnosis, treatment and pathophysiology of IC. ..
  40. Pain Assessment in Cognitively Impaired Children
    Shobha Malviya; Fiscal Year: 2005
    ..A reliable and valid pain assessment tool is critical to facilitate our future study of pain management strategies in these children. ..
  41. ATR in Human Cancer and Anticancer Therapy
    William Cliby; Fiscal Year: 2004
    ..Using xenograft models we will develop a gene therapy model of ATR disruption to test the safety and efficacy of targeting ATR for anticancer therapy. ..
  42. TRIAL TO REDUCE DELIRIUM IN AGED POST ACUTE PATIENTS
    Edward Marcantonio; Fiscal Year: 2004
    ..If the DAP is successful in reducing delirium and improving functional recovery, our findings will serve as a model of a targeted approach to improve the care of elders in the post-acute setting. ..
  43. Pain Medication Use & Risk Factors for Opioid Dependence
    Daniel Solomon; Fiscal Year: 2004
    ..Our goal is to use the results of the proposed research to inform a future intervention to improve opioid prescribing within this large pharmacy benefits program. ..
  44. MIDCAREER INVESTIGATOR AWARD IN CEREBROVASCULAR RESEARCH
    Larry Goldstein; Fiscal Year: 2004
    ....
  45. EFFECTIVENESS OF PRIMARY CARE ALCOHOL INTERVENTIONS
    Katharine Bradley; Fiscal Year: 2004
    ..Finally, I intend to estimate and analyze costs, and the cost- effectiveness, of a mailed, alcohol screening program. ..
  46. AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTION
    HARRY SAX; Fiscal Year: 2004
    ....
  47. AMPHETAMINE ENHANCED STROKE RECOVERY--BURKE SRCI GROUP
    Larry Goldstein; Fiscal Year: 2002
    ..However the treatment duration will be increased to a total of 10 sessions. ..
  48. Impact of Pancreas-Kidney Transplants on Renal Allograft
    Ajay Israni; Fiscal Year: 2002
    ..Renal allograft survival in SPK and KA will be compared using Cox proportional hazards models, adjusting for patient and transplant center characteristics. ..
  49. CANCER AND LEUKEMIA GROUP B
    David Sugarbaker; Fiscal Year: 2002
    ..Three stages of group development are described: (1) surgeon recruitment phase; (2) patient recruitment phase (educational activities about adjuvant therapy trials. etc.); and (3) protocol development phase (intellectual activities). ..
  50. Natural History of POP-- A Prospective Cohort Study
    Ingrid Nygaard; Fiscal Year: 2005
    ..The national cost burden is large. This project will provide fundamental data to guide future decisions about intervention threshold, preventative measures, and risk factor modification. ..
  51. Vascular Access in Hemodialysis Patients
    Michael Allon; Fiscal Year: 2005
    ..The applicant will assist the trainees in acquiring the conceptual skills, research experience, and motivation required to pursue a successful career in Academic Nephrology. ..
  52. E2F-1 Cancer Gene Therapy
    Kelly McMasters; Fiscal Year: 2005
    ..These studies will enhance our understanding of E2F-1-mediated cell death and facilitate the design of improved treatment strategies...
  53. Phytoestrogens, alcohol, and endometrial cancer risk
    ELISA BANDERA; Fiscal Year: 2007
    ..This award will provide the support and training the Candidate needs to develop an independent career in the nutritional epidemiology of cancer. ..
  54. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  55. Better Surgical Quality Indicators for the Elderly
    John Birkmeyer; Fiscal Year: 2007
    ..g., historical mortality or volume alone). [unreadable] [unreadable] [unreadable]..
  56. Evaluation of the AUDIT-C in a Primary Care Population
    Katharine Bradley; Fiscal Year: 2006
    ....
  57. Infection, Persistence & Clearance of Oral HPV in Women
    Jimmy Efird; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  58. Genetic Epidemiology and Renal Allograft Outcomes
    Ajay Israni; Fiscal Year: 2007
    ..By identifying genetic polymorphisms that impact allograft survival, this study will help identify patients at risk and will help in the development of therapies targeting critical pathways...
  59. Osteoporosis in Women with Rheumatoid Arthritis
    Daniel Solomon; Fiscal Year: 2006
    ..This epidemiologic data will inform future trials of osteoporosis treatments among patients with RA. As well, the study cohort will comprise one of the largest RA registries with an explicit plan to examine osteoporosis. ..
  60. GENETICS OF PARKINSON DISEASE IN THE AMISH
    Brad Racette; Fiscal Year: 2006
    ..abstract_text> ..
  61. Randomized Controlled Testing of Osteoporosis Education
    Daniel Solomon; Fiscal Year: 2006
    ..A multi-disciplinary Training Advisory Board will review the applicants progress regularly to ensure that the proposed training goals are met. ..
  62. Polysomal RNA Antitumor Immunity
    John Chi; Fiscal Year: 2005
    ..Results from these experiments will help characterize the potential use of dendritic cells transfected with polysomal RNA in creating antigen specific tumor vaccines for brain tumors. ..
  63. EYE GROWTH DURING INFANCY
    Scott Lambert; Fiscal Year: 2001
    ..In addition, by understanding the mechanisms retarding ocular growth, it may be possible to modulate the excessive ocular growth which occurs in certain pathological conditions such as retinopathy of prematurity. ..
  64. Bell's Palsy-Randomized Clinical Trial
    John Neely; Fiscal Year: 2007
    ..This revised planning grant application is to support necessary preparation for the multicenter trial. [unreadable] [unreadable] [unreadable]..