surgical blood loss

Summary

Summary: Loss of blood during a surgical procedure.

Top Publications

  1. ncbi The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis
    Joanne Guay
    Department of Anesthesia, Maisonneuve Rosemont Hospital, University of Montreal, Montreal, Quebec, Canada H1T 2M4
    J Clin Anesth 18:124-8. 2006
  2. ncbi Prospective, randomized clinical trial of the FloSeal matrix sealant in cardiac surgery
    Giuseppe Nasso
    Cardiac Surgery Department, GVM Hospitals of Care and Research, Bari, Italy
    Ann Thorac Surg 88:1520-6. 2009
  3. ncbi Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe
    Nadia Rosencher
    Cochin Hospital, 27 rue du Fbg St Jacques, 75014 Paris, France
    Transfusion 43:459-69. 2003
  4. ncbi Sutureless laparoscopic heminephrectomy using laser tissue soldering
    Kenneth Ogan
    Department of Urology, The University of Texas Southwestern Meidcal Centre, Dalla, Texas 75390 9110, USA
    J Endourol 17:295-300. 2003
  5. ncbi Reductions in blood loss with a bipolar sealer in total hip arthroplasty
    German A Marulanda
    Department of Orthopaedics and Sports Medicine, University of South Florida, Tampa, FL, USA
    Expert Rev Med Devices 5:125-31. 2008
  6. ncbi A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery
    D T Neilipovitz
    Departments of Anaesthesiology and Critical Care, The Ottawa Hospital, Ottawa, Ontario
    Anesth Analg 93:82-7. 2001
  7. ncbi Coronary artery stenting and non-cardiac surgery--a prospective outcome study
    M N Vicenzi
    Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Austria
    Br J Anaesth 96:686-93. 2006
  8. ncbi Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery
    Navil F Sethna
    Department of Anesthesiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Anesthesiology 102:727-32. 2005
  9. ncbi The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
    Ann Surg Oncol 14:1825-34. 2007
  10. pmc Blood loss in adult spinal surgery
    Serena S Hu
    Department of Orthopedic Surgery, University of California San Francisco, 500 Parnassus Ave MU320West, San Francisco, CA 94143 0728, USA
    Eur Spine J 13:S3-5. 2004

Detail Information

Publications226 found, 100 shown here

  1. ncbi The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis
    Joanne Guay
    Department of Anesthesia, Maisonneuve Rosemont Hospital, University of Montreal, Montreal, Quebec, Canada H1T 2M4
    J Clin Anesth 18:124-8. 2006
    ..The aim of this study was to evaluate the effect of neuraxial blocks on surgical blood losses and on the number of patients requiring blood transfusion...
  2. ncbi Prospective, randomized clinical trial of the FloSeal matrix sealant in cardiac surgery
    Giuseppe Nasso
    Cardiac Surgery Department, GVM Hospitals of Care and Research, Bari, Italy
    Ann Thorac Surg 88:1520-6. 2009
    ..We compared a hemostatic matrix sealant agent (FloSeal; Baxter Inc, Deerfield, IL) with alternative topical hemostatic agents in a mixed cohort of elective cardiac and thoracic aortic operations...
  3. ncbi Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe
    Nadia Rosencher
    Cochin Hospital, 27 rue du Fbg St Jacques, 75014 Paris, France
    Transfusion 43:459-69. 2003
    ..The purpose of this study was to assess current practices in blood management in elective orthopedic surgery in Europe...
  4. ncbi Sutureless laparoscopic heminephrectomy using laser tissue soldering
    Kenneth Ogan
    Department of Urology, The University of Texas Southwestern Meidcal Centre, Dalla, Texas 75390 9110, USA
    J Endourol 17:295-300. 2003
    ..We describe laser tissue welding using human albumin as a solder to control bleeding and seal the collecting system during laparoscopic heminephrectomy in a porcine model...
  5. ncbi Reductions in blood loss with a bipolar sealer in total hip arthroplasty
    German A Marulanda
    Department of Orthopaedics and Sports Medicine, University of South Florida, Tampa, FL, USA
    Expert Rev Med Devices 5:125-31. 2008
    ..It appears to reduce tissue damage and smoke production in comparison with standard electrocautery. These results were found even in patients with demographic characteristics associated with a higher risk of blood-related complications...
  6. ncbi A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery
    D T Neilipovitz
    Departments of Anaesthesiology and Critical Care, The Ottawa Hospital, Ottawa, Ontario
    Anesth Analg 93:82-7. 2001
    ..The administration of prophylactic tranexamic acid in patients with scoliosis undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements...
  7. ncbi Coronary artery stenting and non-cardiac surgery--a prospective outcome study
    M N Vicenzi
    Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Austria
    Br J Anaesth 96:686-93. 2006
    ..Therefore we undertook a prospective, observational multicentre study with predefined heparin therapy and antiplatelet medication in patients undergoing non-cardiac procedures after coronary artery stenting...
  8. ncbi Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery
    Navil F Sethna
    Department of Anesthesiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Anesthesiology 102:727-32. 2005
    ..The authors hypothesized that administration of tranexamic acid would reduce bleeding and transfusion requirements during scoliosis surgery...
  9. ncbi The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
    Ann Surg Oncol 14:1825-34. 2007
    ..Our objective was to determine the relative effects of pylorus-preserving pancreaticoduodenectomy (PPPD) and standard Whipple pancreaticoduodenectomy (SWPD) in patients with pancreatic or periampullary cancer...
  10. pmc Blood loss in adult spinal surgery
    Serena S Hu
    Department of Orthopedic Surgery, University of California San Francisco, 500 Parnassus Ave MU320West, San Francisco, CA 94143 0728, USA
    Eur Spine J 13:S3-5. 2004
    Spinal surgery in adults can vary from simple to complex and can also have variable anticipated surgical blood loss. There are several factors that can put patients at increased risk for greater intraoperative blood loss...
  11. ncbi Predictors of blood transfusions in spinal instrumentation and fusion surgery
    G A Nuttall
    Departments of Anesthesiology, Laboratory Medicine, Orthopedic Surgery, and Statistics, Mayo Clinic, Rochester, Minnesota 55905, USA
    Spine (Phila Pa 1976) 25:596-601. 2000
    ..A retrospective review of 244 adult spine instrumentation and fusion surgery cases (1994-1995) from one institution...
  12. ncbi Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: effects on perioperative bleeding and allogeneic transfusions
    V Casati
    Department of Anesthesiology, University of Milano, Division of Cardiac Anesthesia and Intensive Care, Epidemiology Unit, and Division of Cardiac Surgery, San Raffaele Hospital, Milano, Italy
    J Thorac Cardiovasc Surg 120:520-7. 2000
    ..We compared the effects of tranexamic acid (a synthetic antifibrinolytic drug) with aprotinin (a natural derivative product with antifibrinolytic properties) on perioperative bleeding and the need for allogeneic transfusions...
  13. ncbi Local hemostasis during laparoscopic partial nephrectomy using biodegradable hydrogels: initial porcine results
    Sanjay Ramakumar
    James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, 4940 Eastern Avenue, Baltimore, MD 21224, USA
    J Endourol 16:489-94. 2002
    ....
  14. ncbi Systemic hemostatic medications for reducing surgical blood loss
    B L Erstad
    Department of Pharmacy Practice and Science, College of Pharmacy, Tucson, AZ 85721 0207, USA
    Ann Pharmacother 35:925-34. 2001
    To review randomized trials involving the use of systemic hemostatic medications for reducing surgical blood loss.
  15. ncbi Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis
    W Burger
    Department of Interventional Cardiology, St Georg Hospital, Leipzig, Germany
    J Intern Med 257:399-414. 2005
    ..Aim of the study was to review and quantify cardiovascular risks because of periprocedural aspirin withdrawal and bleeding risks with the continuation of aspirin...
  16. ncbi Comparison of blood-conservation strategies in cardiac surgery patients at high risk for bleeding
    G A Nuttall
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 92:674-82. 2000
    ..Aprotinin and tranexamic acid are routinely used to reduce bleeding in cardiac surgery. There is a large difference in agent price and perhaps in efficacy...
  17. ncbi Prophylactic tranexamic acid and epsilon-aminocaproic acid for primary myocardial revascularization
    J F Hardy
    Department of Anesthesia, Montreal Heart Institute, University of Montreal, Quebec, Canada
    Ann Thorac Surg 65:371-6. 1998
    ..The efficacy of prophylactic epsilon-aminocaproic acid and tranexamic acid to reduce transfusions after primary myocardial revascularization was evaluated in a teaching hospital context...
  18. ncbi Laparoscopic treatment for ureteropelvic junction obstruction
    Tibrio M Siqueira
    Department of Urology, Indiana University School of Medicine, Clarian Health Partners, Indianapolis, Indiana, USA
    Urology 60:973-8. 2002
    ..To assess retrospectively the subjective and objective outcomes achieved after laparoscopic treatment for ureteropelvic junction obstruction at our institutions...
  19. ncbi Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction
    P G Chassot
    Department of Anaesthesiology, University Hospital Lausanne Chuv, CH 1011 Lausanne, Switzerland
    Br J Anaesth 99:316-28. 2007
    ..A therapeutic bridge with shorter-acting antiplatelet drugs may be considered...
  20. ncbi Complications of laparoscopic partial nephrectomy in 200 cases
    Anup P Ramani
    Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    J Urol 173:42-7. 2005
    ..We analyzed complications of the initial 200 cases treated with laparoscopic partial nephrectomy for a suspected renal tumor...
  21. ncbi Robotic assisted laparoscopic radical cystoprostatectomy: operative and pathological outcomes
    Raj S Pruthi
    Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Urol 178:814-8. 2007
    ..We report our initial experience with robotic assisted laparoscopic radical cystoprostatectomy, evaluating the perioperative and pathological outcomes of this novel procedure...
  22. ncbi Laparoscopic partial nephrectomy with a novel electrosurgical snare in a porcine model
    William C Collyer
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    J Endourol 16:673-9. 2002
    ..We evaluated the safety and efficacy of laparoscopic partial nephrectomy with an arcing-gap electrosurgical snare in a porcine model...
  23. ncbi Radical prostatectomy: size of the prostate gland and its relationship with acute perioperative complications
    Shafquat Meraj
    Beth Israel Medical Center, New York, New York, USA
    Can J Urol 10:1743-8. 2003
    ..To determine if there is correlation between the size of radical prostatectomy specimens and perioperative complications including intraoperative blood loss...
  24. ncbi Use of haemostatic agents and glues during laparoscopic partial nephrectomy: a multi-institutional survey from the United States and Europe of 1347 cases
    Alberto Breda
    Department of Urology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA
    Eur Urol 52:798-803. 2007
    ..Haemostatic agents (HAs) and/or glues may reduce haemorrhage and urine leakage. We sought to examine the current practice patterns for urologists performing LPN with regard to HA use and its relationship with bleeding and urine leakage...
  25. ncbi Assessing the body mass index of patients might help to predict blood loss during radical retropubic prostatectomy in Korean men
    In Ho Chang
    Department of Urology, Seoul National University Bundang Hospital, Gumi dong, Bundang gu, Seongnam, Kyunggi Do, Korea 463 707
    BJU Int 99:570-4. 2007
    ....
  26. ncbi Successful transfer of open surgical skills to a laparoscopic environment using a robotic interface: initial experience with laparoscopic radical prostatectomy
    Thomas E Ahlering
    Department of Urology, University of California Irvine, UCI Medical Center, Orange, CA, USA
    J Urol 170:1738-41. 2003
    ..To our knowledge we report the initial experience with robot assisted LRP of a surgeon without laparoscopic experience...
  27. ncbi Objectives and limitations of bloodless medical care
    Aryeh Shander
    Department of Anesthesiology and Critical Care and Hyperbaric Medicine, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
    Curr Opin Hematol 13:462-70. 2006
    ..To outline the rationale, limitations, and execution of bloodless medical and surgical programs, highlighting characteristics that contribute to successful outcomes...
  28. ncbi The effect of amicar on perioperative blood loss in idiopathic scoliosis: the results of a prospective, randomized double-blind study
    Ivan Florentino-Pineda
    Division of Pediatric Anesthesiology, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Spine (Phila Pa 1976) 29:233-8. 2004
    ..A prospective, randomized, double-blind Institutional Review Board-approved study evaluating the efficacy of Amicar (epsilon aminocaproic acid), an antifibrinolytic agent, in decreasing perioperative blood loss in idiopathic scoliosis...
  29. pmc Comprehensive prospective comparative analysis of outcomes between open and laparoscopic radical prostatectomy conducted in 2003 to 2005
    Karim Touijer
    Department of Surgery, Service of Urology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Urol 179:1811-7; discussion 1817. 2008
    ..In a nonrandomized prospective fashion we compared the oncological, functional and morbidity outcomes after laparoscopic and retropubic radical prostatectomy...
  30. ncbi The risk associated with aprotinin in cardiac surgery
    Dennis T Mangano
    Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
    N Engl J Med 354:353-65. 2006
    ..This approach appears counterintuitive to the accepted medical treatment of the same condition--namely, fibrinolysis to limit thrombosis. Despite this concern, no independent, large-scale safety assessment has been undertaken...
  31. ncbi Complications of contemporary radical nephrectomy: comparison of open vs. laparoscopic approach
    Matthew D Shuford
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Urol Oncol 22:121-6. 2004
    ..The low rate of complications combined with the advantages of laparoscopic surgery favor a laparoscopic approach for the majority of patients with stage T1 and T2 tumors...
  32. ncbi Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass
    Sandra Dial
    Department of Critical Care, SMBD Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    J Thorac Cardiovasc Surg 130:654-61. 2005
    ....
  33. ncbi The role of amicar in decreasing perioperative blood loss in idiopathic scoliosis
    George H Thompson
    Division of Pediatric Orthopaedics, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Spine (Phila Pa 1976) 30:S94-9. 2005
    ..Four separate studies on the role of Amicar in decreasing perioperative blood loss in idiopathic scoliosis...
  34. ncbi A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes
    Scott S Reuben
    Department of Anesthesiology, Baystate Medical Center and the Tufts University School of Medicine, Springfield, MA 01199, USA
    Anesth Analg 106:1258-64, table of contents. 2008
    ..The hypothesis of this study is that perioperative administration of celecoxib will improve analgesic efficacy, with a resultant improvement in short- and long-term clinical outcomes after TKA...
  35. ncbi Combining the uterine depletion procedure and myomectomy may be useful for treating symptomatic fibroids
    Wei Min Liu
    Department of Obstetrics and Gynecology, Taipei Medical University Hospital and Taipei Medical University, Taipei, Taiwan
    Fertil Steril 82:205-10. 2004
    ..To evaluate the therapeutic results of premyomectomy uterine depletion for the treatment of symptomatic fibroids, compared with myomectomy only...
  36. ncbi A blood-conservation algorithm to reduce blood transfusions after total hip and knee arthroplasty
    Jeffery L Pierson
    St Vincent Center for Joint Replacement, 8402 Harcourt Road, Suite 128, Indianapolis, IN 46260, USA
    J Bone Joint Surg Am 86:1512-8. 2004
    ..Our hypothesis was that use of this algorithm would reduce the rate of transfusion after unilateral total hip and knee arthroplasty as compared with the rates described in previous reports...
  37. ncbi Oxytocin requirements at elective cesarean delivery: a dose-finding study
    Jose C A Carvalho
    Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada
    Obstet Gynecol 104:1005-10. 2004
    ..The purpose of this study was to estimate the minimum effective intravenous bolus dose of oxytocin (ED90) required for adequate uterine contraction at elective cesarean in nonlaboring women...
  38. ncbi Randomized clinical trial of Ligasure versus open haemorrhoidectomy
    F F Palazzo
    Department of Surgery, Princess Alexandra Hospital, Harlow, UK
    Br J Surg 89:154-7. 2002
    ..Haemorrhoidectomy performed using bloodless bipolar diathermy--Ligasure--may have advantages over conventional open haemorrhoidectomy in terms of operating time and postoperative pain...
  39. ncbi Robotic-assisted laparoscopic partial nephrectomy: surgical technique and clinical outcomes at 1 year
    Henry Ho
    Department of Urology, Medical University of Innsbruck, Innsbruck, Austria
    BJU Int 103:663-8. 2009
    ....
  40. ncbi The TachoSil-Pledget stitch: towards eradication of suture hole bleeding
    Takeshi Shimamoto
    Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Ann Thorac Surg 86:2002-4. 2008
    ....
  41. ncbi The efficacy of antifibrinolytics in the reduction of blood loss during complex adult reconstructive spine surgery
    M K Urban
    Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Spine (Phila Pa 1976) 26:1152-6. 2001
    ..CONCLUSIONS: For complex spinal operations with large blood losses, the half-dose aprotinin regimen will reduce blood loss and the need for blood components and may have a role in reducing postoperative lung injury...
  42. ncbi Cardiac risk of noncardiac surgery after percutaneous coronary intervention with drug-eluting stents
    Jennifer A Rabbitts
    Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Anesthesiology 109:596-604. 2008
    ..The American College of Cardiology released a scientific advisory that included a recommendation to delay elective of noncardiac surgery (NCS) for 1 yr after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)...
  43. ncbi Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints
    M Levi
    Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Lancet 354:1940-7. 1999
    ....
  44. ncbi Reducing blood loss at myomectomy with use of a gelatin-thrombin matrix hemostatic sealant
    Francisco Raga
    Departamento de Obstetricia y Ginecologia, Hospital Clinico Universitario de Valencia, Valencia, Spain
    Fertil Steril 92:356-60. 2009
    ..To evaluate the hemostatic efficacy and handling of gelatin-thrombin matrix in abdominal myomectomy...
  45. ncbi Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators
    A Laupacis
    Clinical Epidemiology Unit, Loeb Research Institute, University of Ottawa, Canada
    Anesth Analg 85:1258-67. 1997
    ..We conclude that aprotinin and tranexamic acid, but not desmopressin, decrease the number of patients exposed to perioperative allogeneic transfusions in association with cardiac surgery...
  46. ncbi Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of 'bridging' antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel
    S Savonitto
    Department of Cardiology, Ospedale Niguarda Ca Granda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy
    Br J Anaesth 104:285-91. 2010
    ..This pilot study tested the hypothesis that the i.v. perioperative administration of the short-acting antiplatelet agent tirofiban allows the safe withdrawal of clopidogrel without increasing the rate of surgical bleeding...
  47. ncbi A randomized, controlled trial comparing effect of oral misoprostol and intravenous syntocinon on intra-operative blood loss during cesarean section
    G Acharya
    Department of Obstetrics and Gynecology, Princess Alexandra Hospital, Harlow, Essex, United Kingdom
    Acta Obstet Gynecol Scand 80:245-50. 2001
    ..CONCLUSION: Oral misoprostol appears to be safe and as effective as intravenous syntocinon in reduction of intra-operative blood loss during elective cesarean section under regional anesthesia and merits further investigation...
  48. ncbi Perioperative blood management practices in elective orthopaedic surgery
    E Michael Keating
    The Center for Hip and Knee Surgery, Mooresville, IN, USA
    J Am Acad Orthop Surg 10:393-400. 2002
    ..The informed selection of alternatives based on preoperative assessment of hematologic status, estimated blood loss, and sources for blood replacement may enhance blood management practices in major elective orthopaedic surgery...
  49. ncbi Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary operations
    R J Dignan
    Prince of Wales Hospital, Sydney, Australia
    Ann Thorac Surg 71:158-63; discussion 163-4. 2001
    ..This study was designed to determine whether a less expensive, ultra-low dose of aprotinin is effective when used in coronary artery bypass grafting with left internal mammary artery...
  50. ncbi The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusion
    Scott S Reuben
    Baystate Medical Center and Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, USA
    J Bone Joint Surg Am 87:536-42. 2005
    ..The goals of the present study were to examine the analgesic efficacy of celecoxib and to determine the incidence of nonunion at one year following spinal fusion surgery...
  51. pmc Intraoperative autologous blood transfusion for hemoperitoneum resulting from ectopic pregnancy or ovarian bleeding during laparoscopic surgery
    Takashi Yamada
    Department of Obstetrics and Gynecology, Hirakata City Hospital, Osaka, Japan
    JSLS 7:97-100. 2003
    ..Our purpose was to evaluate the efficacy and safety of intraoperative autologous blood transfusion during laparoscopic surgery for hemoperitoneum in benign gynecologic disease...
  52. ncbi Update on laparoscopic and robotic radical prostatectomy
    Andras Hoznek
    Service d Urologie, Centre Hospitalier Universitaire Henri Mondor, Creteil, France
    Curr Opin Urol 15:173-80. 2005
    ..In this review, we update the more recent data concerning the results, technical trends and controversies regarding these novel, minimally invasive procedures...
  53. ncbi Predicting blood loss and transfusion requirements during radical prostatectomy: the significant negative impact of increasing body mass index
    Sam S Chang
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 171:1861-5. 2004
    ..We assessed recent blood loss and transfusion requirements in contemporary patients undergoing RRP and examined the possible predictive impact of preoperative variables...
  54. ncbi Robotically assisted laparoscopic transhiatal esophagectomy
    C A Galvani
    Minimally Invasive Surgery Center, University of Illinois, 840 South Wood Street, Room 435, Chicago, IL 60612, USA
    Surg Endosc 22:188-95. 2008
    ..The goal of this report is to describe the authors' early experience using robotically assisted technology to perform transhiatal esophagectomy (RATE)...
  55. ncbi Perioperative blood loss and transfusion requirements in patients with fractured neck of femur
    P D Marval
    Eur J Anaesthesiol 21:412-4. 2004
  56. ncbi Wound drainage versus non-drainage for proximal femoral fractures. A prospective randomised study
    R M Tjeenk
    Department of Traumatology, Red Cross Hospital, The Hague, The Netherlands
    Injury 36:100-4. 2005
    ..The purpose of this prospective randomised study was to examine whether routine drainage in surgery for traumatic hip fractures is useful...
  57. ncbi Laparoscopic hysterectomy using a computer-enhanced surgical robot
    C Diaz-Arrastia
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Surg Endosc 16:1271-3. 2002
    ..The objective of this study was to describe the technique of laparoscopic hysterectomy using a computer-enhanced robotic surgical system...
  58. ncbi [Predicting blood loss during radical prostatectomy using internal pelvimetry]
    Nobuyuki Sekita
    Department of Urology, Chosei Public Hospital
    Hinyokika Kiyo 53:19-23. 2007
    ..Moreover, these data also indicate that blood preparation may be spared in patients with acceptable BMI, wide APE, and good VPA...
  59. ncbi Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases
    H Lepor
    Department of Urology, New York University School of Medicine, New York, New York, USA
    J Urol 166:1729-33. 2001
    ..This outcomes analysis implies that radical retropubic prostatectomy cannot be assumed to have greater morbidity than radiation therapy and it sets a high standard for those advocating laparoscopic radical prostatectomy...
  60. ncbi Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients
    Torsten Johansson
    Division of Orthopaedics and Sports Medicine, Department of Neuroscience and Locomotion, Faculty of Health Sciences, University of Linkoping, Sweden
    Acta Orthop 76:314-9. 2005
    ..The total saving potential is substantial if the blood loss could be reduced. Studies on the use of tranexamic acid have shown interesting results, but its benefits in total hip arthroplasty have not yet been resolved...
  61. ncbi Indications and contraindications of cell salvage
    Jonathan H Waters
    Department of General Anesthesiology and Clinical Pathology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Transfusion 44:40S-4S. 2004
  62. ncbi Treatment of suture line bleeding with a novel synthetic surgical sealant in a canine iliac PTFE graft model
    A Hill
    Department of Cardiothoracic Surgery, University of California, San Francisco, California, USA
    J Biomed Mater Res 58:308-12. 2001
    ..CoSeal significantly reduced the time to hemostasis and blood loss in comparison to tamponade...
  63. ncbi Identifying patients at risk of intraoperative and postoperative transfusion in isolated CABG: toward selective conservation strategies
    Rakesh C Arora
    Division of Cardiac Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Thorac Surg 78:1547-54. 2004
    ..We developed a predictive model, based on eight preoperative risk factors, of allogeneic blood product transfusion rates in patients undergoing a cardiac procedure...
  64. ncbi What happens to hemostatic agents in contact with urine? An in vitro study
    Carlos A Uribe
    Department of Urology, University of California Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
    J Endourol 19:312-7. 2005
    ....
  65. ncbi The effect of preoperative clopidogrel on bleeding after coronary artery bypass surgery
    Wade Kang
    Department of Surgery, St Luke s Hospital and Health Network, Bethlehem, Pennsylvania 18015, USA
    J Surg Educ 64:88-92. 2007
    ..The purpose of this study was to analyze the effect of preoperative clopidogrel exposure on bleeding complications, blood transfusions requirements, and reoperations in patients undergoing coronary artery bypass grafting (CABG)...
  66. ncbi Impact of body mass index on radical cystectomy
    Cheryl T Lee
    Department of Urology, Michigan Urology Center, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Urol 172:1281-5. 2004
    ..Morbid obesity may even preclude definitive surgical treatment. This study examines the impact of body mass index (BMI) on radical cystectomy...
  67. ncbi Minimally invasive total hip arthroplasty: a prospective randomized study
    George F Chimento
    Orthopaedic and Sports Medicine Clinic, 6050 Bullard Avenue, Suite 100, New Orleans, LA 70128, USA
    J Arthroplasty 20:139-44. 2005
    ..Compared with a standard incision, patients who underwent a minimally invasive total hip arthroplasty demonstrated decreased blood loss and limped less at 6-week follow-up...
  68. ncbi Laparoscopic-assisted vaginal hysterectomy with uterine artery ligation through retrograde umbilical ligament tracking
    Wen Chun Chang
    Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    J Minim Invasive Gynecol 12:336-42. 2005
    ..To evaluate the clinical outcomes of uterine artery ligation through retrograde tracking of the umbilical ligament (RUL) in laparoscopic-assisted vaginal hysterectomy (LAVH)...
  69. ncbi Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis
    Frederic Shapiro
    Department of Orthopaedic Surgery, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Spine (Phila Pa 1976) 32:2278-83. 2007
    ..Retrospective review of intraoperative blood loss and blood replacement...
  70. ncbi Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgery
    Jae Kwang Shim
    Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea
    J Thorac Cardiovasc Surg 134:59-64. 2007
    ..This study aimed to determine the effects of aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in off-pump coronary artery bypass grafting...
  71. ncbi Endoscopic transaxillary approach to the thyroid gland: our early experience
    T D Duncan
    Morehouse School of Medicine, Atlanta Medical Center, Atlanta, Georgia, USA
    Surg Endosc 21:2166-71. 2007
    ..Although the majority of surgically excised thyroid lesions are histologically benign, patients are traditionally left with a permanent transverse surgical scar in a highly visible area of the neck...
  72. ncbi Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgery
    V Casati
    Department of Cardiothoracic Anesthesia, University of Milan, San Raffaele Hospital, Italy
    Ann Thorac Surg 68:2252-6; discussion 2256-7. 1999
    ..The effects of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) on bleeding and allogeneic transfusions, and the cost of pharmacological and transfusional treatment were compared to aprotinin (AP)...
  73. ncbi Comparison of short-term outcomes of laparoscopic vs open approaches to ileal pouch surgery
    Henry S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Int J Colorectal Dis 22:531-42. 2007
    ..The present meta-analysis compared short-term outcomes between patients undergoing laparoscopic and open restorative proctocolectomy...
  74. ncbi A prospective, randomized platelet-function study of heparinized oxygenators and cardiotomy suction
    Gregory A Nuttall
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Cardiothorac Vasc Anesth 20:554-61. 2006
    ..The purpose of this study was to determine if substitution of a heparin-coated oxygenator and salvaged autologous blood for cardiotomy suction would improve platelet function...
  75. ncbi Active and mechanical hemostatic agents
    William D Spotnitz
    Surgical Therapeutic Advancement Center, University of Virginia Health System, Charlottesville, VA 22908, USA
    Surgery 142:S34-8. 2007
    ..Research and development continues on potential new products. Improvements in the efficacy of these products as well as delivery systems and product safety will make these agents even better and more widely accepted...
  76. ncbi First experience with robot-assisted thoracoscopic esophagolymphadenectomy for esophageal cancer
    R van Hillegersberg
    Department of Surgery, University Medical Center Utrecht, P O Box 85500, 3508, GA, Utrecht, The Netherlands
    Surg Endosc 20:1435-9. 2006
    ..This morbidity rate could be reduced by the use of minimally invasive techniques. The feasibility of robot-assisted thoracoscopic esophagectomy (RTE) with mediastinal lymphadenectomy was assessed prospectively...
  77. ncbi Risks, benefits, alternatives and indications of allogenic blood transfusions
    C Madjdpour
    Department of Anesthesiology, University Hospital Lausanne, Lausanne, Switzerland
    Minerva Anestesiol 72:283-98. 2006
    ..This information will help the physician to judiciously use RBC transfusions when they are indeed indicated...
  78. ncbi Damage control management of experimental grade 5 renal injuries: further evaluation of FloSeal gelatin matrix
    Nathan F Pursifull
    Urology Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78324, USA
    J Trauma 60:346-50. 2006
    ..We developed a porcine grade 5 renal laceration damage control model to evaluate the hemostatic efficacy of FloSeal gelatin matrix (Baxter Healthcare, Corp., Deerfield, Ill)...
  79. ncbi Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer
    Marco Niedergethmann
    Department of Surgery, University Hospital Mannheim, University of Heidelberg, 68135, Mannheim, Germany
    Langenbecks Arch Surg 391:195-202. 2006
    ..The aim of this study was to compare nutritional and functional results of the different techniques in a retrospective evaluation and prospective cohort study...
  80. ncbi Intraoperative blood loss and transfusion requirements for robotic-assisted radical prostatectomy versus radical retropubic prostatectomy
    Scott B Farnham
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Urology 67:360-3. 2006
    ..To compare intraoperative blood loss, perioperative hematocrit, and transfusion requirements in patients undergoing radical retropubic prostatectomy (RRP) versus robotic-assisted laparoscopic prostatectomy (RALP) by a single surgeon...
  81. ncbi Prasugrel: a review of its use in patients with acute coronary syndromes undergoing percutaneous coronary intervention
    Sean T Duggan
    Wolters Kluwer Health Adis, 41 Centorian Drive, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 69:1707-26. 2009
    ..Thus, prasugrel provides a new option for the management of patients with ACS who are undergoing PCI; the risk-benefit ratio should be carefully assessed before intensive antiplatelet therapy with prasugrel is initiated...
  82. ncbi Blood loss after total hip replacement: a prospective randomized study between wound compression and drainage
    Torsten Johansson
    Division of Orthopaedics and Sports Medicine, Department of Neuroscience and Locomotion, Faculty of Health Sciences, University of Linkoping, Linkoping, Sweden
    J Arthroplasty 20:967-71. 2005
    ..Wound discharge was more frequent in controls (19/54 vs 8/51; P = .04). Thus, wound compression had no obvious negative effects and reduced wound discharge and need for transfusion. It may replace drainage after total hip arthroplasty...
  83. ncbi Premature preoperative discontinuation of antiplatelet drug therapy in cardiovascular risk patients: a preliminary study on the role of P2Y12 receptor monitoring
    Helfried Metzler
    Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austria
    Eur J Anaesthesiol 27:138-45. 2010
    ..New platelet function tests, such as the vasodilator-stimulated phosphoprotein phosphorylation assay, may help to assess the perioperative status of the clopidogrel-specific P2Y12 receptor...
  84. pmc Total laparoscopic hysterectomy versus total abdominal hysterectomy: cohort review of patients with uterine neoplasia
    Katherine A O'Hanlan
    Gynecologic Oncology Associates, Palo Alto, California, USA
    JSLS 9:277-86. 2005
    ..Retrospective analysis of surgico-pathologic data comparing total laparoscopic hysterectomy (TLH) with total abdominal hysterectomy (TAH) patients with uterine neoplasia...
  85. ncbi Suture line reinforcement using suction-assisted bioglue application during surgery for acute aortic dissection
    Zan Mitrev
    Special Hospital for Cardiac Surgery Filip II, 1000 Skopje, Macedonia
    Interact Cardiovasc Thorac Surg 6:147-9. 2007
    ..Average daily chest tube drainage was 582+/-150 ml/day, with the duration of drainage of 2+/-0.9 days. In conclusion, this new hemostatic technique is simple to use and demonstrates excellent, immediate and early postoperative results...
  86. ncbi BioGlue surgical adhesive for thoracic aortic repair during coagulopathy: efficacy and histopathology
    C W Hewitt
    Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper Hospital University Medical Center, Camden, USA
    Ann Thorac Surg 71:1609-12. 2001
    ....
  87. ncbi Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgery
    Marian L T Bugter
    Department of Anaesthesiology, Sint Maartensklinick, PO Box 9011, 6500 GM Nijmegen, The Netherlands
    Can J Anaesth 50:445-9. 2003
    ..The objective was to use NSAID for preoperative pain reduction and at the same time use the NSAID exposure to reduce opioid requirements for pain inhibition in major orthopedic surgery...
  88. pmc Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspective
    Judith Martini
    Department of Bioengineering, University of California, San Diego, Gilman Dr, La Jolla, California 92093, USA
    Crit Care 12:R54. 2008
    Preoperative hemodilution is an established practice that is applied to reduce surgical blood loss. It has been proposed that polyethylene glycol (PEG) surface decorated proteins such as PEG-conjugated human serum albumin may be used as ..
  89. ncbi The impact of a 10-year audit cycle on blood usage in a district general hospital
    R M James
    Department of Haematology, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RS, UK
    Transfus Med 11:371-5. 2001
    ..The audit is now being expanded again to include a greater focus on usage of cross-matched blood in the nonsurgical setting...
  90. pmc Perioperative erythropoietin administration in patients with gastrointestinal tract cancer: prospective randomized double-blind study
    Nicholas Kosmadakis
    First Department of Propaedeutic Surgery, Hippokration General Hospital, Athens Medical School, University of Athens, Greece
    Ann Surg 237:417-21. 2003
    ....
  91. ncbi A randomized study of total abdominal, vaginal and laparoscopic hysterectomy
    S C Ribeiro
    Department of Obstetric and Gynecology, Clinics Hospital of São Paulo University School of Medicine HCFMUSP, Sao Paulo, SP, Brazil
    Int J Gynaecol Obstet 83:37-43. 2003
    ..To evaluate operative time, blood loss and inflammatory response in patients submitted to hysterectomy...
  92. ncbi Increased body mass index predicts increased blood loss during radical cystectomy
    Sam S Chang
    Department of Urologic Surgery and Patient Care Services, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 171:1077-9. 2004
    ..We evaluated the impact of body mass index (BMI), an objective measure of obesity, on operative and perioperative outcomes in patients undergoing radical cystectomy...
  93. ncbi Robot-assisted laparoscopic radical prostatectomy: perioperative outcomes of 1500 cases
    Vipul R Patel
    Global Robotics Institute, Celebration Health University of Central Florida, Orlando, Celebration, Florida 34747, USA
    J Endourol 22:2299-305. 2008
    ..Robot-assisted laparoscopic radical prostatectomy (RALP) is an evolving minimally invasive treatment of for localized prostate cancer. We present our experience of 1500 consecutive cases with an analysis of perioperative outcomes...
  94. ncbi A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than gelfoam/thrombin: results of a randomized controlled trial
    Marc Glickman
    Virginia Vascular Associates, 880 Kempsville Rd, Suite 1000, Norfolk, VA 23502, USA
    Arch Surg 137:326-31; discussion 332. 2002
    ..An experimental polymeric sealant (CoSeal [Cohesion Technologies, Palo Alto, Calif]) provides equivalent anastomotic sealing to Gelfoam (Upjohn, Kalamazoo, Mich)/thrombin during surgical placement of prosthetic vascular grafts...
  95. ncbi Radical cystectomy with ileal conduit diversion: early prospective evaluation of the impact of robotic assistance
    Jonathan J Rhee
    Department of Urology, University of Virginia, Charlottesville, VA 22908, USA
    BJU Int 98:1059-63. 2006
    ..To compare the performance of radical cystectomy with ileal conduit diversion by standard methods with that using the assistance of the daVinci robotic system (Intuitive Surgical, Sunnyvale, CA, USA)...
  96. ncbi The potential role of aprotinin in the perioperative management of malignant tumors
    Ara A Vaporciyan
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
    J Am Coll Surg 198:266-78. 2004
  97. ncbi Improved intraoperative management of anastomotic bleeding during aortic reconstruction: results of a randomized controlled trial
    Robert C Hagberg
    Seltara Norfolk General Hospital, Norfolk, Virginia, USA
    Am Surg 70:307-11. 2004
    ..These results support the use of this novel sealant for the intraoperative management of anastomotic bleeding during aortic reconstruction procedures...
  98. ncbi Single-center comparison of purely laparoscopic, hand-assisted laparoscopic, and open radical nephrectomy in patients at high anesthetic risk
    D Duane Baldwin
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Endourol 17:161-7. 2003
    ....
  99. ncbi Coronary artery stents: II. Perioperative considerations and management
    Lisa T Newsome
    Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
    Anesth Analg 107:570-90. 2008
    ..Algorithms for perioperative management of patients with bare-metal and drug-eluting stents are proposed...
  100. ncbi Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial
    Asokumar Buvanendran
    Department of Anesthesiology, Rush Medical College at Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    JAMA 290:2411-8. 2003
    ..Controlling postoperative pain after knee replacement while reducing opioid-induced adverse effects and improving outcomes remains an important challenge...
  101. ncbi The inflammatory response to recycled pericardial suction blood and the influence of cell-saving
    Staffan Svenmarker
    Department of Surgical and Perioperative Science, Umea University Hospital, Sweden
    Scand Cardiovasc J 37:158-64. 2003
    ..To investigate the inflammatory and cellular response attributed to conventional cardiotomy suction vs cell-saver during cardiac surgery...

Research Grants30

  1. Novel Protein-Free Material for Minimally Compressive Surgical Hemostasis
    PATRICK STEVEN COTTLER; Fiscal Year: 2010
    ..I.) The material to be developed will provide a low-cost, low-risk alternative to current treatments for surgical blood loss, including transfusions and protein-based hemostatic agents...
  2. Chitosan hemostatic device for laparoscopic applications
    Hua Xie; Fiscal Year: 2005
    ..abstract_text> ..
  3. Role of Coagulation System Variability: Cardiac Surgery
    Brian Donahue; Fiscal Year: 2006
    ..The project will make extensive use of data in the Vanderbilt Cardiac Surgery Registry, a valuable database of genetic and clinical data presently being prospectively collected on elective adult cardiac surgery patients...
  4. Systematic Integration POR into Clinical Pathway of HCC
    Myron Schwartz; Fiscal Year: 2006
    ..This program provides a truly remarkable opportunity to make meaningful progress in understanding, preventing and treating HCC, while in the process providing fertile training ground for young physician-scientists. ..
  5. Safety of Lumbar Fusion Surgery for Chronic Back Pain
    Sohail Mirza; Fiscal Year: 2006
    ..The analysis will use appropriate univariate and multivariate techniques to address the study questions. This study will provide data on the relative benefits and risks of lumbar fusion surgery in treating back pain. ..
  6. Immune Thrombocytopenia and Low-Level Mercury Exposure
    Jodi Segal; Fiscal Year: 2006
    ..Segal with the necessary support for successful completion [unreadable] [unreadable] [unreadable]..
  7. APOE Genotype and Sequelae of Infant Cardiac Surgery
    James Gaynor; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  8. Physician Training Program in Neonatal Biology
    John Widness; Fiscal Year: 2007
    ..With NIH support beyond that which the investigators currently enjoy, the investigators will be able to significantly enhance the research training experiences they offer their postdoctoral physician trainees in neonatal medicine. ..
  9. IMMUNOLOGIC STUDIES OF PATIENTS AFTER TRAUMATIC INJURY
    James A Lederer; Fiscal Year: 2010
    ..abstract_text> ..
  10. Nanostenting Hydrogels for Sinus Surgery
    RICHARD ORLANDI; Fiscal Year: 2004
    ..The results of these Phase I studies will determine the feasibility and the optimal chemical properties of a nanostenting HA gel for human trials. ..
  11. PHARMACOGENETICS IN SURGICAL CRITICAL CARE
    Bradley Freeman; Fiscal Year: 2004
    ..The environment for this project is Washington University School of Medicine, an institution with access to a large clinical volume and established expertise in genomic research. ..
  12. CHLORHEXIDINE IRRIGATION TO PREVENT INFECTION
    Dwight Rouse; Fiscal Year: 2001
    ....
  13. Microbiology/Immunology of Periodontal Disease in T1DM
    Paul Moore; Fiscal Year: 2002
    ..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
  14. MIDCAREER AWARD IN PATIENT ORIENTED OBSTETRIC RESEARCH
    Dwight Rouse; Fiscal Year: 2004
    ..Finally, the effectiveness of an intervention (how it would perform under conditions of actual clinical practice) is an attribute that, in many situations, is as important as its efficacy (how it performs under ideal conditions). ..
  15. Instrument to Measure Oxygen Affinity of Hemoglobin
    Kim Vandegriff; Fiscal Year: 2004
    ..abstract_text> ..
  16. ORGAN HEMOSTASIS IN TRAUMA BY HIGH INTENSITY ULTRASOUND
    Shahram Vaezy; Fiscal Year: 2003
    ..Thus, the investigators believe that their proposed studies will result in a new and clinically applicable methodology for reducing mortality and morbidity in abnormal trauma. ..
  17. Effect of lipid modification on peripheral arterial disease (PAD)
    Christie Ballantyne; Fiscal Year: 2007
    ..Finally, these studies will advance our understanding of the molecular mechanisms of inflammation and thrombosis associated with aggressive lipid modification. ..
  18. Neurophysiologic Development Responses to Surgery
    DOUGLAS RIRIE; Fiscal Year: 2007
    ..Through this and future studies which come from this data and training, improvement in understanding will hopefully lead to improved pain therapy that is developmentally appropriate. ..
  19. Focused Ultrasound for Treatment of Nerves
    Shahram Vaezy; Fiscal Year: 2008
    ..It is our goal to develop image- guided focused ultrasound as a non-invasive alternative for the treatment of spasticity and pain. ..
  20. Angiogenesis and Cardiac Growth as Heart Failure Therapy
    Y Woo; Fiscal Year: 2008
    ..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
  21. INJURY-INDUCED EFFECTS ON THE ADAPTIVE IMMUNE SYSTEM
    James Lederer; Fiscal Year: 2007
    ..It is hoped that the results of these studies will advance the development of treatments designed to prevent the development of immune system failure and infectious complications following severe injury. ..
  22. A Molecular Signature of Early Cervical Carcinoma
    Concepcion Diaz Arrastia; Fiscal Year: 2007
    ..I propose to identify a genomic and proteomic signature of cervical cancer that will predict the aggressive behavior of the tumor and function clinically to develop molecular-based treatment plans. ..
  23. ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTS
    Paul Moore; Fiscal Year: 2003
    ..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..
  24. UTERINE TUMOR TREATMENT USING HIGH INTENSITY ULTRASOUND
    Shahram Vaezy; Fiscal Year: 2003
    ..Ultimately, this treatment approach may also provide an option to preserve fertility and improve reproductive outcomes in patients with fibroid tumors. ..
  25. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
  26. Genomics of Peripheral Arterial Disease
    Jeffrey Lawson; Fiscal Year: 2006
    ..abstract_text> ..
  27. Postoperative Cognitive Dysfunction in the Elderly
    Terri Monk; Fiscal Year: 2004
    ..Given the breadth of my proposed training program, I will be able to interact with and serve as a mentor for anesthesiologists and also the broader corpus of scientists, both clinical and basic, interested in aging and neuroscience. ..
  28. Oral Care and Respiratory Pathogen Colonization
    Ozan Akca; Fiscal Year: 2004
    ..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
  29. Enriched IVIG for the treatment of West Nile Virus
    Israel Nur; Fiscal Year: 2005
    ..In the absence of sufficient WN antibodies in convalescent donors, hyper-immune donors treated with an attenuated vaccine may be explored as an alternative source of plasma. ..
  30. Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)
    Christian Schmidt; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..