Genomes and Genes
surgical blood loss
Summary: Loss of blood during a surgical procedure.
Publications226 found, 100 shown here
- The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysisJoanne Guay
Department of Anesthesia, Maisonneuve Rosemont Hospital, University of Montreal, Montreal, Quebec, Canada H1T 2M4
J Clin Anesth 18:124-8. 2006..The aim of this study was to evaluate the effect of neuraxial blocks on surgical blood losses and on the number of patients requiring blood transfusion...
- Prospective, randomized clinical trial of the FloSeal matrix sealant in cardiac surgeryGiuseppe Nasso
Cardiac Surgery Department, GVM Hospitals of Care and Research, Bari, Italy
Ann Thorac Surg 88:1520-6. 2009..We compared a hemostatic matrix sealant agent (FloSeal; Baxter Inc, Deerfield, IL) with alternative topical hemostatic agents in a mixed cohort of elective cardiac and thoracic aortic operations...
- Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in EuropeNadia Rosencher
Cochin Hospital, 27 rue du Fbg St Jacques, 75014 Paris, France
Transfusion 43:459-69. 2003..The purpose of this study was to assess current practices in blood management in elective orthopedic surgery in Europe...
- Sutureless laparoscopic heminephrectomy using laser tissue solderingKenneth Ogan
Department of Urology, The University of Texas Southwestern Meidcal Centre, Dalla, Texas 75390 9110, USA
J Endourol 17:295-300. 2003..We describe laser tissue welding using human albumin as a solder to control bleeding and seal the collecting system during laparoscopic heminephrectomy in a porcine model...
- Reductions in blood loss with a bipolar sealer in total hip arthroplastyGerman A Marulanda
Department of Orthopaedics and Sports Medicine, University of South Florida, Tampa, FL, USA
Expert Rev Med Devices 5:125-31. 2008..It appears to reduce tissue damage and smoke production in comparison with standard electrocautery. These results were found even in patients with demographic characteristics associated with a higher risk of blood-related complications...
- A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgeryD T Neilipovitz
Departments of Anaesthesiology and Critical Care, The Ottawa Hospital, Ottawa, Ontario
Anesth Analg 93:82-7. 2001..The administration of prophylactic tranexamic acid in patients with scoliosis undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements...
- Coronary artery stenting and non-cardiac surgery--a prospective outcome studyM N Vicenzi
Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Austria
Br J Anaesth 96:686-93. 2006..Therefore we undertook a prospective, observational multicentre study with predefined heparin therapy and antiplatelet medication in patients undergoing non-cardiac procedures after coronary artery stenting...
- Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgeryNavil F Sethna
Department of Anesthesiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Anesthesiology 102:727-32. 2005..The authors hypothesized that administration of tranexamic acid would reduce bleeding and transfusion requirements during scoliosis surgery...
- The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancerPaul J Karanicolas
Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
Ann Surg Oncol 14:1825-34. 2007..Our objective was to determine the relative effects of pylorus-preserving pancreaticoduodenectomy (PPPD) and standard Whipple pancreaticoduodenectomy (SWPD) in patients with pancreatic or periampullary cancer...
- Blood loss in adult spinal surgerySerena S Hu
Department of Orthopedic Surgery, University of California San Francisco, 500 Parnassus Ave MU320West, San Francisco, CA 94143 0728, USA
Eur Spine J 13:S3-5. 2004Spinal surgery in adults can vary from simple to complex and can also have variable anticipated surgical blood loss. There are several factors that can put patients at increased risk for greater intraoperative blood loss...
- Predictors of blood transfusions in spinal instrumentation and fusion surgeryG A Nuttall
Departments of Anesthesiology, Laboratory Medicine, Orthopedic Surgery, and Statistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Spine (Phila Pa 1976) 25:596-601. 2000..A retrospective review of 244 adult spine instrumentation and fusion surgery cases (1994-1995) from one institution...
- Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: effects on perioperative bleeding and allogeneic transfusionsV Casati
Department of Anesthesiology, University of Milano, Division of Cardiac Anesthesia and Intensive Care, Epidemiology Unit, and Division of Cardiac Surgery, San Raffaele Hospital, Milano, Italy
J Thorac Cardiovasc Surg 120:520-7. 2000..We compared the effects of tranexamic acid (a synthetic antifibrinolytic drug) with aprotinin (a natural derivative product with antifibrinolytic properties) on perioperative bleeding and the need for allogeneic transfusions...
- Local hemostasis during laparoscopic partial nephrectomy using biodegradable hydrogels: initial porcine resultsSanjay Ramakumar
James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, 4940 Eastern Avenue, Baltimore, MD 21224, USA
J Endourol 16:489-94. 2002....
- Systemic hemostatic medications for reducing surgical blood lossB L Erstad
Department of Pharmacy Practice and Science, College of Pharmacy, Tucson, AZ 85721 0207, USA
Ann Pharmacother 35:925-34. 2001To review randomized trials involving the use of systemic hemostatic medications for reducing surgical blood loss.
- Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysisW Burger
Department of Interventional Cardiology, St Georg Hospital, Leipzig, Germany
J Intern Med 257:399-414. 2005..Aim of the study was to review and quantify cardiovascular risks because of periprocedural aspirin withdrawal and bleeding risks with the continuation of aspirin...
- Comparison of blood-conservation strategies in cardiac surgery patients at high risk for bleedingG A Nuttall
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 92:674-82. 2000..Aprotinin and tranexamic acid are routinely used to reduce bleeding in cardiac surgery. There is a large difference in agent price and perhaps in efficacy...
- Prophylactic tranexamic acid and epsilon-aminocaproic acid for primary myocardial revascularizationJ F Hardy
Department of Anesthesia, Montreal Heart Institute, University of Montreal, Quebec, Canada
Ann Thorac Surg 65:371-6. 1998..The efficacy of prophylactic epsilon-aminocaproic acid and tranexamic acid to reduce transfusions after primary myocardial revascularization was evaluated in a teaching hospital context...
- Laparoscopic treatment for ureteropelvic junction obstructionTibrio M Siqueira
Department of Urology, Indiana University School of Medicine, Clarian Health Partners, Indianapolis, Indiana, USA
Urology 60:973-8. 2002..To assess retrospectively the subjective and objective outcomes achieved after laparoscopic treatment for ureteropelvic junction obstruction at our institutions...
- Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarctionP G Chassot
Department of Anaesthesiology, University Hospital Lausanne Chuv, CH 1011 Lausanne, Switzerland
Br J Anaesth 99:316-28. 2007..A therapeutic bridge with shorter-acting antiplatelet drugs may be considered...
- Complications of laparoscopic partial nephrectomy in 200 casesAnup P Ramani
Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
J Urol 173:42-7. 2005..We analyzed complications of the initial 200 cases treated with laparoscopic partial nephrectomy for a suspected renal tumor...
- Robotic assisted laparoscopic radical cystoprostatectomy: operative and pathological outcomesRaj S Pruthi
Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
J Urol 178:814-8. 2007..We report our initial experience with robotic assisted laparoscopic radical cystoprostatectomy, evaluating the perioperative and pathological outcomes of this novel procedure...
- Laparoscopic partial nephrectomy with a novel electrosurgical snare in a porcine modelWilliam C Collyer
Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
J Endourol 16:673-9. 2002..We evaluated the safety and efficacy of laparoscopic partial nephrectomy with an arcing-gap electrosurgical snare in a porcine model...
- Radical prostatectomy: size of the prostate gland and its relationship with acute perioperative complicationsShafquat Meraj
Beth Israel Medical Center, New York, New York, USA
Can J Urol 10:1743-8. 2003..To determine if there is correlation between the size of radical prostatectomy specimens and perioperative complications including intraoperative blood loss...
- Use of haemostatic agents and glues during laparoscopic partial nephrectomy: a multi-institutional survey from the United States and Europe of 1347 casesAlberto Breda
Department of Urology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA
Eur Urol 52:798-803. 2007..Haemostatic agents (HAs) and/or glues may reduce haemorrhage and urine leakage. We sought to examine the current practice patterns for urologists performing LPN with regard to HA use and its relationship with bleeding and urine leakage...
- Assessing the body mass index of patients might help to predict blood loss during radical retropubic prostatectomy in Korean menIn Ho Chang
Department of Urology, Seoul National University Bundang Hospital, Gumi dong, Bundang gu, Seongnam, Kyunggi Do, Korea 463 707
BJU Int 99:570-4. 2007....
- Successful transfer of open surgical skills to a laparoscopic environment using a robotic interface: initial experience with laparoscopic radical prostatectomyThomas E Ahlering
Department of Urology, University of California Irvine, UCI Medical Center, Orange, CA, USA
J Urol 170:1738-41. 2003..To our knowledge we report the initial experience with robot assisted LRP of a surgeon without laparoscopic experience...
- Objectives and limitations of bloodless medical careAryeh Shander
Department of Anesthesiology and Critical Care and Hyperbaric Medicine, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Curr Opin Hematol 13:462-70. 2006..To outline the rationale, limitations, and execution of bloodless medical and surgical programs, highlighting characteristics that contribute to successful outcomes...
- The effect of amicar on perioperative blood loss in idiopathic scoliosis: the results of a prospective, randomized double-blind studyIvan Florentino-Pineda
Division of Pediatric Anesthesiology, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
Spine (Phila Pa 1976) 29:233-8. 2004..A prospective, randomized, double-blind Institutional Review Board-approved study evaluating the efficacy of Amicar (epsilon aminocaproic acid), an antifibrinolytic agent, in decreasing perioperative blood loss in idiopathic scoliosis...
- Comprehensive prospective comparative analysis of outcomes between open and laparoscopic radical prostatectomy conducted in 2003 to 2005Karim Touijer
Department of Surgery, Service of Urology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Urol 179:1811-7; discussion 1817. 2008..In a nonrandomized prospective fashion we compared the oncological, functional and morbidity outcomes after laparoscopic and retropubic radical prostatectomy...
- The risk associated with aprotinin in cardiac surgeryDennis T Mangano
Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
N Engl J Med 354:353-65. 2006..This approach appears counterintuitive to the accepted medical treatment of the same condition--namely, fibrinolysis to limit thrombosis. Despite this concern, no independent, large-scale safety assessment has been undertaken...
- Complications of contemporary radical nephrectomy: comparison of open vs. laparoscopic approachMatthew D Shuford
Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Urol Oncol 22:121-6. 2004..The low rate of complications combined with the advantages of laparoscopic surgery favor a laparoscopic approach for the majority of patients with stage T1 and T2 tumors...
- Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypassSandra Dial
Department of Critical Care, SMBD Jewish General Hospital, McGill University, Montreal, Quebec, Canada
J Thorac Cardiovasc Surg 130:654-61. 2005....
- The role of amicar in decreasing perioperative blood loss in idiopathic scoliosisGeorge H Thompson
Division of Pediatric Orthopaedics, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Spine (Phila Pa 1976) 30:S94-9. 2005..Four separate studies on the role of Amicar in decreasing perioperative blood loss in idiopathic scoliosis...
- A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomesScott S Reuben
Department of Anesthesiology, Baystate Medical Center and the Tufts University School of Medicine, Springfield, MA 01199, USA
Anesth Analg 106:1258-64, table of contents. 2008..The hypothesis of this study is that perioperative administration of celecoxib will improve analgesic efficacy, with a resultant improvement in short- and long-term clinical outcomes after TKA...
- Combining the uterine depletion procedure and myomectomy may be useful for treating symptomatic fibroidsWei Min Liu
Department of Obstetrics and Gynecology, Taipei Medical University Hospital and Taipei Medical University, Taipei, Taiwan
Fertil Steril 82:205-10. 2004..To evaluate the therapeutic results of premyomectomy uterine depletion for the treatment of symptomatic fibroids, compared with myomectomy only...
- A blood-conservation algorithm to reduce blood transfusions after total hip and knee arthroplastyJeffery L Pierson
St Vincent Center for Joint Replacement, 8402 Harcourt Road, Suite 128, Indianapolis, IN 46260, USA
J Bone Joint Surg Am 86:1512-8. 2004..Our hypothesis was that use of this algorithm would reduce the rate of transfusion after unilateral total hip and knee arthroplasty as compared with the rates described in previous reports...
- Oxytocin requirements at elective cesarean delivery: a dose-finding studyJose C A Carvalho
Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada
Obstet Gynecol 104:1005-10. 2004..The purpose of this study was to estimate the minimum effective intravenous bolus dose of oxytocin (ED90) required for adequate uterine contraction at elective cesarean in nonlaboring women...
- Randomized clinical trial of Ligasure versus open haemorrhoidectomyF F Palazzo
Department of Surgery, Princess Alexandra Hospital, Harlow, UK
Br J Surg 89:154-7. 2002..Haemorrhoidectomy performed using bloodless bipolar diathermy--Ligasure--may have advantages over conventional open haemorrhoidectomy in terms of operating time and postoperative pain...
- Robotic-assisted laparoscopic partial nephrectomy: surgical technique and clinical outcomes at 1 yearHenry Ho
Department of Urology, Medical University of Innsbruck, Innsbruck, Austria
BJU Int 103:663-8. 2009....
- The TachoSil-Pledget stitch: towards eradication of suture hole bleedingTakeshi Shimamoto
Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Ann Thorac Surg 86:2002-4. 2008....
- The efficacy of antifibrinolytics in the reduction of blood loss during complex adult reconstructive spine surgeryM K Urban
Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
Spine (Phila Pa 1976) 26:1152-6. 2001..CONCLUSIONS: For complex spinal operations with large blood losses, the half-dose aprotinin regimen will reduce blood loss and the need for blood components and may have a role in reducing postoperative lung injury...
- Cardiac risk of noncardiac surgery after percutaneous coronary intervention with drug-eluting stentsJennifer A Rabbitts
Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
Anesthesiology 109:596-604. 2008..The American College of Cardiology released a scientific advisory that included a recommendation to delay elective of noncardiac surgery (NCS) for 1 yr after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)...
- Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpointsM Levi
Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Lancet 354:1940-7. 1999....
- Reducing blood loss at myomectomy with use of a gelatin-thrombin matrix hemostatic sealantFrancisco Raga
Departamento de Obstetricia y Ginecologia, Hospital Clinico Universitario de Valencia, Valencia, Spain
Fertil Steril 92:356-60. 2009..To evaluate the hemostatic efficacy and handling of gelatin-thrombin matrix in abdominal myomectomy...
- Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) InvestigatorsA Laupacis
Clinical Epidemiology Unit, Loeb Research Institute, University of Ottawa, Canada
Anesth Analg 85:1258-67. 1997..We conclude that aprotinin and tranexamic acid, but not desmopressin, decrease the number of patients exposed to perioperative allogeneic transfusions in association with cardiac surgery...
- Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of 'bridging' antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrelS Savonitto
Department of Cardiology, Ospedale Niguarda Ca Granda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy
Br J Anaesth 104:285-91. 2010..This pilot study tested the hypothesis that the i.v. perioperative administration of the short-acting antiplatelet agent tirofiban allows the safe withdrawal of clopidogrel without increasing the rate of surgical bleeding...
- A randomized, controlled trial comparing effect of oral misoprostol and intravenous syntocinon on intra-operative blood loss during cesarean sectionG Acharya
Department of Obstetrics and Gynecology, Princess Alexandra Hospital, Harlow, Essex, United Kingdom
Acta Obstet Gynecol Scand 80:245-50. 2001..CONCLUSION: Oral misoprostol appears to be safe and as effective as intravenous syntocinon in reduction of intra-operative blood loss during elective cesarean section under regional anesthesia and merits further investigation...
- Perioperative blood management practices in elective orthopaedic surgeryE Michael Keating
The Center for Hip and Knee Surgery, Mooresville, IN, USA
J Am Acad Orthop Surg 10:393-400. 2002..The informed selection of alternatives based on preoperative assessment of hematologic status, estimated blood loss, and sources for blood replacement may enhance blood management practices in major elective orthopaedic surgery...
- Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary operationsR J Dignan
Prince of Wales Hospital, Sydney, Australia
Ann Thorac Surg 71:158-63; discussion 163-4. 2001..This study was designed to determine whether a less expensive, ultra-low dose of aprotinin is effective when used in coronary artery bypass grafting with left internal mammary artery...
- The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusionScott S Reuben
Baystate Medical Center and Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, USA
J Bone Joint Surg Am 87:536-42. 2005..The goals of the present study were to examine the analgesic efficacy of celecoxib and to determine the incidence of nonunion at one year following spinal fusion surgery...
- Intraoperative autologous blood transfusion for hemoperitoneum resulting from ectopic pregnancy or ovarian bleeding during laparoscopic surgeryTakashi Yamada
Department of Obstetrics and Gynecology, Hirakata City Hospital, Osaka, Japan
JSLS 7:97-100. 2003..Our purpose was to evaluate the efficacy and safety of intraoperative autologous blood transfusion during laparoscopic surgery for hemoperitoneum in benign gynecologic disease...
- Update on laparoscopic and robotic radical prostatectomyAndras Hoznek
Service d Urologie, Centre Hospitalier Universitaire Henri Mondor, Creteil, France
Curr Opin Urol 15:173-80. 2005..In this review, we update the more recent data concerning the results, technical trends and controversies regarding these novel, minimally invasive procedures...
- Predicting blood loss and transfusion requirements during radical prostatectomy: the significant negative impact of increasing body mass indexSam S Chang
Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
J Urol 171:1861-5. 2004..We assessed recent blood loss and transfusion requirements in contemporary patients undergoing RRP and examined the possible predictive impact of preoperative variables...
- Robotically assisted laparoscopic transhiatal esophagectomyC A Galvani
Minimally Invasive Surgery Center, University of Illinois, 840 South Wood Street, Room 435, Chicago, IL 60612, USA
Surg Endosc 22:188-95. 2008..The goal of this report is to describe the authors' early experience using robotically assisted technology to perform transhiatal esophagectomy (RATE)...
- Perioperative blood loss and transfusion requirements in patients with fractured neck of femurP D Marval
Eur J Anaesthesiol 21:412-4. 2004
- Wound drainage versus non-drainage for proximal femoral fractures. A prospective randomised studyR M Tjeenk
Department of Traumatology, Red Cross Hospital, The Hague, The Netherlands
Injury 36:100-4. 2005..The purpose of this prospective randomised study was to examine whether routine drainage in surgery for traumatic hip fractures is useful...
- Laparoscopic hysterectomy using a computer-enhanced surgical robotC Diaz-Arrastia
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA
Surg Endosc 16:1271-3. 2002..The objective of this study was to describe the technique of laparoscopic hysterectomy using a computer-enhanced robotic surgical system...
- [Predicting blood loss during radical prostatectomy using internal pelvimetry]Nobuyuki Sekita
Department of Urology, Chosei Public Hospital
Hinyokika Kiyo 53:19-23. 2007..Moreover, these data also indicate that blood preparation may be spared in patients with acceptable BMI, wide APE, and good VPA...
- Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 casesH Lepor
Department of Urology, New York University School of Medicine, New York, New York, USA
J Urol 166:1729-33. 2001..This outcomes analysis implies that radical retropubic prostatectomy cannot be assumed to have greater morbidity than radiation therapy and it sets a high standard for those advocating laparoscopic radical prostatectomy...
- Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patientsTorsten Johansson
Division of Orthopaedics and Sports Medicine, Department of Neuroscience and Locomotion, Faculty of Health Sciences, University of Linkoping, Sweden
Acta Orthop 76:314-9. 2005..The total saving potential is substantial if the blood loss could be reduced. Studies on the use of tranexamic acid have shown interesting results, but its benefits in total hip arthroplasty have not yet been resolved...
- Indications and contraindications of cell salvageJonathan H Waters
Department of General Anesthesiology and Clinical Pathology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Transfusion 44:40S-4S. 2004
- Treatment of suture line bleeding with a novel synthetic surgical sealant in a canine iliac PTFE graft modelA Hill
Department of Cardiothoracic Surgery, University of California, San Francisco, California, USA
J Biomed Mater Res 58:308-12. 2001..CoSeal significantly reduced the time to hemostasis and blood loss in comparison to tamponade...
- Identifying patients at risk of intraoperative and postoperative transfusion in isolated CABG: toward selective conservation strategiesRakesh C Arora
Division of Cardiac Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
Ann Thorac Surg 78:1547-54. 2004..We developed a predictive model, based on eight preoperative risk factors, of allogeneic blood product transfusion rates in patients undergoing a cardiac procedure...
- What happens to hemostatic agents in contact with urine? An in vitro studyCarlos A Uribe
Department of Urology, University of California Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
J Endourol 19:312-7. 2005....
- The effect of preoperative clopidogrel on bleeding after coronary artery bypass surgeryWade Kang
Department of Surgery, St Luke s Hospital and Health Network, Bethlehem, Pennsylvania 18015, USA
J Surg Educ 64:88-92. 2007..The purpose of this study was to analyze the effect of preoperative clopidogrel exposure on bleeding complications, blood transfusions requirements, and reoperations in patients undergoing coronary artery bypass grafting (CABG)...
- Impact of body mass index on radical cystectomyCheryl T Lee
Department of Urology, Michigan Urology Center, University of Michigan, Ann Arbor, Michigan 48109, USA
J Urol 172:1281-5. 2004..Morbid obesity may even preclude definitive surgical treatment. This study examines the impact of body mass index (BMI) on radical cystectomy...
- Minimally invasive total hip arthroplasty: a prospective randomized studyGeorge F Chimento
Orthopaedic and Sports Medicine Clinic, 6050 Bullard Avenue, Suite 100, New Orleans, LA 70128, USA
J Arthroplasty 20:139-44. 2005..Compared with a standard incision, patients who underwent a minimally invasive total hip arthroplasty demonstrated decreased blood loss and limped less at 6-week follow-up...
- Laparoscopic-assisted vaginal hysterectomy with uterine artery ligation through retrograde umbilical ligament trackingWen Chun Chang
Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
J Minim Invasive Gynecol 12:336-42. 2005..To evaluate the clinical outcomes of uterine artery ligation through retrograde tracking of the umbilical ligament (RUL) in laparoscopic-assisted vaginal hysterectomy (LAVH)...
- Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosisFrederic Shapiro
Department of Orthopaedic Surgery, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Spine (Phila Pa 1976) 32:2278-83. 2007..Retrospective review of intraoperative blood loss and blood replacement...
- Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgeryJae Kwang Shim
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea
J Thorac Cardiovasc Surg 134:59-64. 2007..This study aimed to determine the effects of aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in off-pump coronary artery bypass grafting...
- Endoscopic transaxillary approach to the thyroid gland: our early experienceT D Duncan
Morehouse School of Medicine, Atlanta Medical Center, Atlanta, Georgia, USA
Surg Endosc 21:2166-71. 2007..Although the majority of surgically excised thyroid lesions are histologically benign, patients are traditionally left with a permanent transverse surgical scar in a highly visible area of the neck...
- Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgeryV Casati
Department of Cardiothoracic Anesthesia, University of Milan, San Raffaele Hospital, Italy
Ann Thorac Surg 68:2252-6; discussion 2256-7. 1999..The effects of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) on bleeding and allogeneic transfusions, and the cost of pharmacological and transfusional treatment were compared to aprotinin (AP)...
- Comparison of short-term outcomes of laparoscopic vs open approaches to ileal pouch surgeryHenry S Tilney
Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
Int J Colorectal Dis 22:531-42. 2007..The present meta-analysis compared short-term outcomes between patients undergoing laparoscopic and open restorative proctocolectomy...
- A prospective, randomized platelet-function study of heparinized oxygenators and cardiotomy suctionGregory A Nuttall
Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 20:554-61. 2006..The purpose of this study was to determine if substitution of a heparin-coated oxygenator and salvaged autologous blood for cardiotomy suction would improve platelet function...
- Active and mechanical hemostatic agentsWilliam D Spotnitz
Surgical Therapeutic Advancement Center, University of Virginia Health System, Charlottesville, VA 22908, USA
Surgery 142:S34-8. 2007..Research and development continues on potential new products. Improvements in the efficacy of these products as well as delivery systems and product safety will make these agents even better and more widely accepted...
- First experience with robot-assisted thoracoscopic esophagolymphadenectomy for esophageal cancerR van Hillegersberg
Department of Surgery, University Medical Center Utrecht, P O Box 85500, 3508, GA, Utrecht, The Netherlands
Surg Endosc 20:1435-9. 2006..This morbidity rate could be reduced by the use of minimally invasive techniques. The feasibility of robot-assisted thoracoscopic esophagectomy (RTE) with mediastinal lymphadenectomy was assessed prospectively...
- Risks, benefits, alternatives and indications of allogenic blood transfusionsC Madjdpour
Department of Anesthesiology, University Hospital Lausanne, Lausanne, Switzerland
Minerva Anestesiol 72:283-98. 2006..This information will help the physician to judiciously use RBC transfusions when they are indeed indicated...
- Damage control management of experimental grade 5 renal injuries: further evaluation of FloSeal gelatin matrixNathan F Pursifull
Urology Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78324, USA
J Trauma 60:346-50. 2006..We developed a porcine grade 5 renal laceration damage control model to evaluate the hemostatic efficacy of FloSeal gelatin matrix (Baxter Healthcare, Corp., Deerfield, Ill)...
- Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancerMarco Niedergethmann
Department of Surgery, University Hospital Mannheim, University of Heidelberg, 68135, Mannheim, Germany
Langenbecks Arch Surg 391:195-202. 2006..The aim of this study was to compare nutritional and functional results of the different techniques in a retrospective evaluation and prospective cohort study...
- Intraoperative blood loss and transfusion requirements for robotic-assisted radical prostatectomy versus radical retropubic prostatectomyScott B Farnham
Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
Urology 67:360-3. 2006..To compare intraoperative blood loss, perioperative hematocrit, and transfusion requirements in patients undergoing radical retropubic prostatectomy (RRP) versus robotic-assisted laparoscopic prostatectomy (RALP) by a single surgeon...
- Prasugrel: a review of its use in patients with acute coronary syndromes undergoing percutaneous coronary interventionSean T Duggan
Wolters Kluwer Health Adis, 41 Centorian Drive, Mairangi Bay, North Shore 0754, Auckland, New Zealand
Drugs 69:1707-26. 2009..Thus, prasugrel provides a new option for the management of patients with ACS who are undergoing PCI; the risk-benefit ratio should be carefully assessed before intensive antiplatelet therapy with prasugrel is initiated...
- Blood loss after total hip replacement: a prospective randomized study between wound compression and drainageTorsten Johansson
Division of Orthopaedics and Sports Medicine, Department of Neuroscience and Locomotion, Faculty of Health Sciences, University of Linkoping, Linkoping, Sweden
J Arthroplasty 20:967-71. 2005..Wound discharge was more frequent in controls (19/54 vs 8/51; P = .04). Thus, wound compression had no obvious negative effects and reduced wound discharge and need for transfusion. It may replace drainage after total hip arthroplasty...
- Premature preoperative discontinuation of antiplatelet drug therapy in cardiovascular risk patients: a preliminary study on the role of P2Y12 receptor monitoringHelfried Metzler
Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austria
Eur J Anaesthesiol 27:138-45. 2010..New platelet function tests, such as the vasodilator-stimulated phosphoprotein phosphorylation assay, may help to assess the perioperative status of the clopidogrel-specific P2Y12 receptor...
- Total laparoscopic hysterectomy versus total abdominal hysterectomy: cohort review of patients with uterine neoplasiaKatherine A O'Hanlan
Gynecologic Oncology Associates, Palo Alto, California, USA
JSLS 9:277-86. 2005..Retrospective analysis of surgico-pathologic data comparing total laparoscopic hysterectomy (TLH) with total abdominal hysterectomy (TAH) patients with uterine neoplasia...
- Suture line reinforcement using suction-assisted bioglue application during surgery for acute aortic dissectionZan Mitrev
Special Hospital for Cardiac Surgery Filip II, 1000 Skopje, Macedonia
Interact Cardiovasc Thorac Surg 6:147-9. 2007..Average daily chest tube drainage was 582+/-150 ml/day, with the duration of drainage of 2+/-0.9 days. In conclusion, this new hemostatic technique is simple to use and demonstrates excellent, immediate and early postoperative results...
- BioGlue surgical adhesive for thoracic aortic repair during coagulopathy: efficacy and histopathologyC W Hewitt
Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper Hospital University Medical Center, Camden, USA
Ann Thorac Surg 71:1609-12. 2001....
- Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgeryMarian L T Bugter
Department of Anaesthesiology, Sint Maartensklinick, PO Box 9011, 6500 GM Nijmegen, The Netherlands
Can J Anaesth 50:445-9. 2003..The objective was to use NSAID for preoperative pain reduction and at the same time use the NSAID exposure to reduce opioid requirements for pain inhibition in major orthopedic surgery...
- Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspectiveJudith Martini
Department of Bioengineering, University of California, San Diego, Gilman Dr, La Jolla, California 92093, USA
Crit Care 12:R54. 2008Preoperative hemodilution is an established practice that is applied to reduce surgical blood loss. It has been proposed that polyethylene glycol (PEG) surface decorated proteins such as PEG-conjugated human serum albumin may be used as ..
- The impact of a 10-year audit cycle on blood usage in a district general hospitalR M James
Department of Haematology, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RS, UK
Transfus Med 11:371-5. 2001..The audit is now being expanded again to include a greater focus on usage of cross-matched blood in the nonsurgical setting...
- Perioperative erythropoietin administration in patients with gastrointestinal tract cancer: prospective randomized double-blind studyNicholas Kosmadakis
First Department of Propaedeutic Surgery, Hippokration General Hospital, Athens Medical School, University of Athens, Greece
Ann Surg 237:417-21. 2003....
- A randomized study of total abdominal, vaginal and laparoscopic hysterectomyS C Ribeiro
Department of Obstetric and Gynecology, Clinics Hospital of São Paulo University School of Medicine HCFMUSP, Sao Paulo, SP, Brazil
Int J Gynaecol Obstet 83:37-43. 2003..To evaluate operative time, blood loss and inflammatory response in patients submitted to hysterectomy...
- Increased body mass index predicts increased blood loss during radical cystectomySam S Chang
Department of Urologic Surgery and Patient Care Services, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
J Urol 171:1077-9. 2004..We evaluated the impact of body mass index (BMI), an objective measure of obesity, on operative and perioperative outcomes in patients undergoing radical cystectomy...
- Robot-assisted laparoscopic radical prostatectomy: perioperative outcomes of 1500 casesVipul R Patel
Global Robotics Institute, Celebration Health University of Central Florida, Orlando, Celebration, Florida 34747, USA
J Endourol 22:2299-305. 2008..Robot-assisted laparoscopic radical prostatectomy (RALP) is an evolving minimally invasive treatment of for localized prostate cancer. We present our experience of 1500 consecutive cases with an analysis of perioperative outcomes...
- A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than gelfoam/thrombin: results of a randomized controlled trialMarc Glickman
Virginia Vascular Associates, 880 Kempsville Rd, Suite 1000, Norfolk, VA 23502, USA
Arch Surg 137:326-31; discussion 332. 2002..An experimental polymeric sealant (CoSeal [Cohesion Technologies, Palo Alto, Calif]) provides equivalent anastomotic sealing to Gelfoam (Upjohn, Kalamazoo, Mich)/thrombin during surgical placement of prosthetic vascular grafts...
- Radical cystectomy with ileal conduit diversion: early prospective evaluation of the impact of robotic assistanceJonathan J Rhee
Department of Urology, University of Virginia, Charlottesville, VA 22908, USA
BJU Int 98:1059-63. 2006..To compare the performance of radical cystectomy with ileal conduit diversion by standard methods with that using the assistance of the daVinci robotic system (Intuitive Surgical, Sunnyvale, CA, USA)...
- The potential role of aprotinin in the perioperative management of malignant tumorsAra A Vaporciyan
Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
J Am Coll Surg 198:266-78. 2004
- Improved intraoperative management of anastomotic bleeding during aortic reconstruction: results of a randomized controlled trialRobert C Hagberg
Seltara Norfolk General Hospital, Norfolk, Virginia, USA
Am Surg 70:307-11. 2004..These results support the use of this novel sealant for the intraoperative management of anastomotic bleeding during aortic reconstruction procedures...
- Single-center comparison of purely laparoscopic, hand-assisted laparoscopic, and open radical nephrectomy in patients at high anesthetic riskD Duane Baldwin
Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
J Endourol 17:161-7. 2003....
- Coronary artery stents: II. Perioperative considerations and managementLisa T Newsome
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
Anesth Analg 107:570-90. 2008..Algorithms for perioperative management of patients with bare-metal and drug-eluting stents are proposed...
- Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trialAsokumar Buvanendran
Department of Anesthesiology, Rush Medical College at Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
JAMA 290:2411-8. 2003..Controlling postoperative pain after knee replacement while reducing opioid-induced adverse effects and improving outcomes remains an important challenge...
- The inflammatory response to recycled pericardial suction blood and the influence of cell-savingStaffan Svenmarker
Department of Surgical and Perioperative Science, Umea University Hospital, Sweden
Scand Cardiovasc J 37:158-64. 2003..To investigate the inflammatory and cellular response attributed to conventional cardiotomy suction vs cell-saver during cardiac surgery...
- Novel Protein-Free Material for Minimally Compressive Surgical HemostasisPATRICK STEVEN COTTLER; Fiscal Year: 2010..I.) The material to be developed will provide a low-cost, low-risk alternative to current treatments for surgical blood loss, including transfusions and protein-based hemostatic agents...
- Chitosan hemostatic device for laparoscopic applicationsHua Xie; Fiscal Year: 2005..abstract_text> ..
- Role of Coagulation System Variability: Cardiac SurgeryBrian Donahue; Fiscal Year: 2006..The project will make extensive use of data in the Vanderbilt Cardiac Surgery Registry, a valuable database of genetic and clinical data presently being prospectively collected on elective adult cardiac surgery patients...
- Systematic Integration POR into Clinical Pathway of HCCMyron Schwartz; Fiscal Year: 2006..This program provides a truly remarkable opportunity to make meaningful progress in understanding, preventing and treating HCC, while in the process providing fertile training ground for young physician-scientists. ..
- Safety of Lumbar Fusion Surgery for Chronic Back PainSohail Mirza; Fiscal Year: 2006..The analysis will use appropriate univariate and multivariate techniques to address the study questions. This study will provide data on the relative benefits and risks of lumbar fusion surgery in treating back pain. ..
- Immune Thrombocytopenia and Low-Level Mercury ExposureJodi Segal; Fiscal Year: 2006..Segal with the necessary support for successful completion [unreadable] [unreadable] [unreadable]..
- APOE Genotype and Sequelae of Infant Cardiac SurgeryJames Gaynor; Fiscal Year: 2007..unreadable] [unreadable]..
- Physician Training Program in Neonatal BiologyJohn Widness; Fiscal Year: 2007..With NIH support beyond that which the investigators currently enjoy, the investigators will be able to significantly enhance the research training experiences they offer their postdoctoral physician trainees in neonatal medicine. ..
- IMMUNOLOGIC STUDIES OF PATIENTS AFTER TRAUMATIC INJURYJames A Lederer; Fiscal Year: 2010..abstract_text> ..
- Nanostenting Hydrogels for Sinus SurgeryRICHARD ORLANDI; Fiscal Year: 2004..The results of these Phase I studies will determine the feasibility and the optimal chemical properties of a nanostenting HA gel for human trials. ..
- PHARMACOGENETICS IN SURGICAL CRITICAL CAREBradley Freeman; Fiscal Year: 2004..The environment for this project is Washington University School of Medicine, an institution with access to a large clinical volume and established expertise in genomic research. ..
- CHLORHEXIDINE IRRIGATION TO PREVENT INFECTIONDwight Rouse; Fiscal Year: 2001....
- Microbiology/Immunology of Periodontal Disease in T1DMPaul Moore; Fiscal Year: 2002..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
- MIDCAREER AWARD IN PATIENT ORIENTED OBSTETRIC RESEARCHDwight Rouse; Fiscal Year: 2004..Finally, the effectiveness of an intervention (how it would perform under conditions of actual clinical practice) is an attribute that, in many situations, is as important as its efficacy (how it performs under ideal conditions). ..
- Instrument to Measure Oxygen Affinity of HemoglobinKim Vandegriff; Fiscal Year: 2004..abstract_text> ..
- ORGAN HEMOSTASIS IN TRAUMA BY HIGH INTENSITY ULTRASOUNDShahram Vaezy; Fiscal Year: 2003..Thus, the investigators believe that their proposed studies will result in a new and clinically applicable methodology for reducing mortality and morbidity in abnormal trauma. ..
- Effect of lipid modification on peripheral arterial disease (PAD)Christie Ballantyne; Fiscal Year: 2007..Finally, these studies will advance our understanding of the molecular mechanisms of inflammation and thrombosis associated with aggressive lipid modification. ..
- Neurophysiologic Development Responses to SurgeryDOUGLAS RIRIE; Fiscal Year: 2007..Through this and future studies which come from this data and training, improvement in understanding will hopefully lead to improved pain therapy that is developmentally appropriate. ..
- Focused Ultrasound for Treatment of NervesShahram Vaezy; Fiscal Year: 2008..It is our goal to develop image- guided focused ultrasound as a non-invasive alternative for the treatment of spasticity and pain. ..
- Angiogenesis and Cardiac Growth as Heart Failure TherapyY Woo; Fiscal Year: 2008..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
- INJURY-INDUCED EFFECTS ON THE ADAPTIVE IMMUNE SYSTEMJames Lederer; Fiscal Year: 2007..It is hoped that the results of these studies will advance the development of treatments designed to prevent the development of immune system failure and infectious complications following severe injury. ..
- A Molecular Signature of Early Cervical CarcinomaConcepcion Diaz Arrastia; Fiscal Year: 2007..I propose to identify a genomic and proteomic signature of cervical cancer that will predict the aggressive behavior of the tumor and function clinically to develop molecular-based treatment plans. ..
- ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTSPaul Moore; Fiscal Year: 2003..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..
- UTERINE TUMOR TREATMENT USING HIGH INTENSITY ULTRASOUNDShahram Vaezy; Fiscal Year: 2003..Ultimately, this treatment approach may also provide an option to preserve fertility and improve reproductive outcomes in patients with fibroid tumors. ..
- URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERSGUNHILDE BUCHSBAUM; Fiscal Year: 2003..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
- Genomics of Peripheral Arterial DiseaseJeffrey Lawson; Fiscal Year: 2006..abstract_text> ..
- Postoperative Cognitive Dysfunction in the ElderlyTerri Monk; Fiscal Year: 2004..Given the breadth of my proposed training program, I will be able to interact with and serve as a mentor for anesthesiologists and also the broader corpus of scientists, both clinical and basic, interested in aging and neuroscience. ..
- Oral Care and Respiratory Pathogen ColonizationOzan Akca; Fiscal Year: 2004..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
- Enriched IVIG for the treatment of West Nile VirusIsrael Nur; Fiscal Year: 2005..In the absence of sufficient WN antibodies in convalescent donors, hyper-immune donors treated with an attenuated vaccine may be explored as an alternative source of plasma. ..
- Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)Christian Schmidt; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..