Genomes and Genes
Summary: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.
Publications243 found, 100 shown here
- Hemorrhage following tonsillectomy and adenoidectomy in 15,218 patientsJ P Windfuhr
Department of Otorhinolaryngology, Plastic Head and Neck Surgery, St Anna Hospital, Duisburg, Germany
Otolaryngol Head Neck Surg 132:281-6. 2005..To evaluate potential risk factors and the incidence of bleeding following adenoidectomy or tonsillectomy, with or without adenoidectomy requiring surgical treatment under general anesthesia...
- Technical feasibility of endoscopic submucosal dissection for early gastric cancer in patients taking anti-coagulants or anti-platelet agentsS Ono
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo, Tokyo 113 8655, Japan
Dig Liver Dis 41:725-8. 2009..Anti-coagulants and anti-platelet agents are widely used, especially in elderly patients, to prevent thromboembolic disease. However, the feasibility of endoscopic submucosal dissection for such patients has not been investigated...
- Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?Paul Zufferey
Department of Anesthesiology and Intensive Care and EA3065, Thrombosis Research Group, University Hospital of Saint Etienne, Saint Etienne, France
Anesthesiology 105:1034-46. 2006..Although the results suggest that aprotinin and tranexamic acid significantly reduce allogeneic erythrocyte transfusion, further evaluation of safety is required before recommending the use of antifibrinolytics in orthopedic surgery...
- False aneurysm of the sphenopalatine artery after a Le Fort I osteotomy: report of 2 casesOlindo Procopio
Department of Maxillofacial Surgery, University of Padova Medical and Dental School, Padova, Italy
J Oral Maxillofac Surg 61:520-4; discussion 524-5. 2003
- Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacementL Good
Department of Orthopaedics, Faculty of Health Sciences, University of Linkoping, Sweden
Br J Anaesth 90:596-9. 2003..Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known...
- Use of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical proceduresHeather J Ipema
Drug Information Group, University of Illinois at Chicago, Chicago, IL, USA
Ann Pharmacother 46:97-107. 2012..To evaluate the literature describing topical use of tranexamic acid or aminocaproic acid for prevention of postoperative bleeding after major surgical procedures...
- Increased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: implications of a prospective studyRüdiger Gerlach
Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt Main, Germany
Stroke 33:1618-23. 2002..The objective of this prospective study was to determine the incidence and clinical relevance of perioperative decreased factor XIII with respect to standard coagulation parameters and the occurrence of postoperative hematoma...
- The aprotinin story--is BART the final chapter?Wayne A Ray
N Engl J Med 358:2398-400. 2008
- Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trialJean Wong
Department of Anesthesia, Toronto Western Hospital, University of Toronto, 2MC 434, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
J Bone Joint Surg Am 92:2503-13. 2010..The objective of the present trial was to assess the efficacy and safety of the topical application of tranexamic acid on postoperative blood loss in patients undergoing primary unilateral total knee arthroplasty with cement...
- Hidden blood loss after surgery for hip fractureN B Foss
Hvidovre University Hospital, Copenhagen, Denmark
J Bone Joint Surg Br 88:1053-9. 2006..We conclude that total blood loss after surgery for hip fracture is much greater than that observed intra-operatively. Frequent post-operative measurements of haemoglobin are necessary to avoid anaemia...
- Relationship between factor XIII activity, fibrinogen, haemostasis screening tests and postoperative bleeding in cardiopulmonary bypass surgeryMarkus Blome
Clinic for Cardiac Surgery, Institute of Hemostaseology, Academic City Hospital, D 67063 Ludwigshafen, Germany
Thromb Haemost 93:1101-7. 2005..There is however an inverse association between preoperative or postoperative plasma fibrinogen levels and postoperative bleeding. These findings indicate a modulation of postoperative bleeding by fibrinogen levels...
- Visceral artery pseudoaneurysms following pancreatoduodenectomyEseroghene Otah
Department of Surgery, Our Lady of Mercy Medical Center, Bronx, NY, USA
Arch Surg 137:55-9. 2002..These patients all had "herald" bleeding from their abdominal drains. Subsequent angiography and therapeutic embolizations were successfully performed...
- Effect of clopidogrel on bleeding and transfusions after off-pump coronary artery bypass graft surgery: impact of discontinuation prior to surgerySimon Maltais
Department of Cardiac Surgery, CHUM Hopital Notre Dame, Montreal, QC, Canada
Eur J Cardiothorac Surg 34:127-31. 2008..We evaluated the effect of aspirin and clopidogrel (CPDG), both irreversible platelet aggregation inhibitors, on operative bleeding and determined the optimal timing for their discontinuation before surgery...
- Risk factors for complications of endoscopic submucosal dissection in gastric tumors: analysis of 478 lesionsKotaro Mannen
Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, 5 1 1 Nabeshima, Saga 849 8501, Japan
J Gastroenterol 45:30-6. 2010..Endoscopic submucosal dissection (ESD) technique has facilitated en bloc removal of widely spread lesions from the stomach. This retrospective study aimed to determine factors associated with serious complications of ESD...
- Delayed hemorrhage after pancreaticoduodenectomySeong Ho Choi
Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea South Korea
J Am Coll Surg 199:186-91. 2004b>Postoperative hemorrhage, particularly delayed hemorrhage after pancreaticoduodenectomy, is a serious complication and one of the most common causes of mortality after pancreaticoduodenectomy.
- Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patientsA Bergenfelz
Scandanavian Quality Register for Thyroid and Parathyroid Surgery, Lund, Sweden
Langenbecks Arch Surg 393:667-73. 2008..During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce...
- Chemoprophylaxis without intra-articular wound drainage can replace autotransfusion in primary TKAHervé Hourlier
Department of Orthopedic Surgery, Polyclinique de la Thiérache, Wignehies, France
Orthopedics 34:154. 2011..Chemoprophylaxis proved superior to reinfusion at decreasing blood transfusion requirements in the routine daily setting of unilateral cemented primary TKA...
- Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplastyHirotaka Mutsuzaki
Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami, Ami Machi, Inashiki Gun, Ibaraki 300 0394, Japan
J Orthop Surg Res 7:32. 2012..In a retrospective study, we explored whether postoperative intra-articular retrograde injection of tranexamic acid (TA) and leaving a drain clamp in place for 1 h reduced blood loss...
- [Dabigatran therapy--perioperative management and interpretation of coagulation tests]M Spannagl
Haemostaseologie Campus Innenstadt, Klinikum der Universitat Munchen, Munchen, Germany
Hamostaseologie 32:294-305. 2012..A distinct feature of dabigatran is the possibility of effectively removing dabigatran from the circulation by haemodialysis...
- Dabigatran in patients with atrial fibrillation: perioperative and periinterventional managementA Weltermann
Department of Medicine I, Elisabethinen Hospital Linz, Fadinger Straße 1, 4020, Linz, Austria
Wien Klin Wochenschr 124:340-7. 2012....
- Pseudoaneurysm of the facial artery as a late complication of bilateral sagittal split osteotomy and facial traumaMansoor Madani
Department of Oral and Maxillofacial Surgery, Capital Health System, Trenton, New Jersey, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:579-84. 2010....
- Efficient strategy for controlling postoperative hemorrhage in total knee arthroplastyHideyuki Sasanuma
Department of Orthopaedic Surgery, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, 3290498, Japan
Knee Surg Sports Traumatol Arthrosc 19:921-5. 2011....
- Is nasal packing necessary after septoplasty? A meta-analysisSarfaraz M Banglawala
Otolaryngology Head and Neck Surgery, McMaster University, Hamilton, Ontario, Canada
Int Forum Allergy Rhinol 3:418-24. 2013..The purpose of this work was to perform a meta-analysis on the existing literature to evaluate the role of nasal packing after septoplasty...
- Unusual late vascular complications of sagittal split osteotomy of the mandibular ramusJui Pin Lai
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital in Kaohsiung, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
J Craniofac Surg 16:664-8. 2005..Awareness of the possible late vascular complications to facilitate early detection and management is also important...
- Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patientsRajesh N Maniar
Department of Orthopaedic Surgery, Lilavati Hospital and Research Centre, A 791, Bandra Reclamation, Bandra W, Mumbai 400050, India
Clin Orthop Relat Res 470:2605-12. 2012..The antifibrinolytic tranexamic acid reduces surgical blood loss, but studies have not identified an optimal regimen...
- FloSeal use in endoscopic sinus surgery: effect on postoperative bleeding and synechiae formationMark Jameson
Department of Otolaryngology Head and Neck Surgery, University of Virginia Health System, Charlottesville, VA, USA
Am J Otolaryngol 27:86-90. 2006..The objective of this study is to evaluate the effect of the hemostatic agent, FloSeal (FS), on bleeding and healing after functional endoscopic sinus surgery...
- Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packingKonrad G Kastl
Department of Otorhinolaryngology, University Hospital Ulm, University of Ulm, Germany
Eur Arch Otorhinolaryngol 266:1239-43. 2009..In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design...
- Anesthesia for intranasal surgery: a comparison between tracheal intubation and the flexible reinforced laryngeal mask airwayA C Webster
Department of Anaesthesia, St Joseph s Health Centre, University of Western Ontario, London, Canada
Anesth Analg 88:421-5. 1999..There were no significant differences in the incidence of airway complications between Groups II and III...
- Factors associated with excessive bleeding in cardiopulmonary bypass patients: a nested case-control studyJuan J Jimenez Rivera
Intensive Care Unit, University Hospital of Canary Islands, La Laguna, Spain
J Cardiothorac Surg 2:17. 2007..Less than 50% of patients undergoing re-intervention exhibit surgical sources of bleeding. We studied clinical and genetic factors associated with EB...
- 15-year audit of post-tonsillectomy haemorrhage at Dunedin HospitalEmily A Macassey
Department of Otorhinolaryngology, Head and Neck Surgery, Dunedin Public Hospital, and Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
ANZ J Surg 77:579-82. 2007..3% (P<0.0001, 95% confidence interval 8.5-22.5%). The increase is coincidental with the change-over to predominant diathermy technique and a routine use of postoperative non-steroidal anti-inflammatory drugs and steroids...
- Migration of steel-wire coils into the stomach after transcatheter arterial embolization for a bleeding splenic artery pseudoaneurysm: report of a caseT Takahashi
Department of Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan
Surg Today 31:458-62. 2001..By occluding the PSA in this way, the subsequent migration of steel-wire coils into the pseudocyst and stomach might have been prevented in our patient...
- Nonsteroidal antiinflammatory drugs and the risk of operative site bleeding after tonsillectomy: a quantitative systematic reviewSteen Møiniche
Department of Anesthesiology and Intensive Care Medicine, Herlev University Hospital, Copenhagen, Denmark
Anesth Analg 96:68-77, table of contents. 2003..83) and number-needed-to-treat, 60 (95% CI, 34-277). Compared with opioids, NSAIDs were equianalgesic, and the risk of emesis was significantly decreased (relative risk, 0.73; 95% CI, 0.63-0.85; numbers-needed-to-treat, 9; 95% CI, 5-19)...
- Incidence of post-tonsillectomy hemorrhage in children and adults: a study of 4,848 patientsJochen P Windfuhr
Department of Otorhinolaryngology Plastic Head and Neck Surgery, St Anna Hospital, 47259 Duisburg, Albertus Magnus Str 33, Germany
Ear Nose Throat J 81:626-8, 630, 632 passim. 2002..Awareness of these risk factors should help improve patient care and outcomes...
- Diagnostic computed tomographic angiography and therapeutic emergency transcatheter arterial embolization for management of postoperative hemorrhage after gynecologic laparoscopic surgeryAkihiro Takeda
Department of Obstetrics and Gynecology, Gifu Prefectural Tajimi Hospital, Gifu, Japan
J Minim Invasive Gynecol 15:332-41. 2008..To evaluate the diagnostic value of 3-dimensional computed tomographic (CT) angiography and treatment efficacy of emergency transcatheter arterial embolization (TAE) for early postoperative hemorrhage after gynecologic laparoscopic surgery.
- [Spectrum and bleeding complications of sonographically guided interventions of the liver and pancreas]M Frieser
Medizinische Klinik 1, NOZ, Universitat Erlangen Nurnberg, Ulmenweg 18, Erlangen
Ultraschall Med 30:168-74. 2009..Interventions with needles with a larger diameter seem to cause more complications. In search of potential complications, we examined 1923 sonographically guided interventions of the liver and pancreas in a retrospective analysis...
- Review and application of serine protease inhibition in coronary artery bypass graft surgeryLaura Engles
School of Pharmacy, University of Connecticut, 69 North Eagleville Road, Unit 3092, Storrs, CT 06269 3092, USA
Am J Health Syst Pharm 62:S9-14. 2005..These responses are largely mediated by serine proteases such as kallikrein, thrombin, and plasmin...
- Dexamethasone and tonsillectomy bleeding: a meta-analysisAlon Geva
Department of Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
Otolaryngol Head Neck Surg 144:838-43. 2011..To use meta-analytic techniques to examine the effect of dexamethasone on the risk of postoperative bleeding following tonsillectomy...
- Platelet-dense granule deficiency causes postoperative hemorrhage in patients receiving enoxaparin: a novel observation with dramatic clinical implicationsMark D Kligman
Department of Surgery, University of Maryland, Baltimore, MD 21201 1595, USA
Am J Surg 197:365-70. 2009..We hypothesized that administration of LMWH may unmask latent platelet dysfunction and result in postoperative hemorrhage.
- The effect of preoperative dexamethasone on early oral intake, vomiting and pain after tonsillectomyM Nil Kaan
Adnan Menderes University, School of Medicine, Department of Anesthesiology and Reanimation, 09100 Aydin, Turkey
Int J Pediatr Otorhinolaryngol 70:73-9. 2006..5 mg/kg i.v. dexamethasone on postoperative early oral intake, pain, vomiting in patients undergoing adenotonsillectomy while performing standard anesthesia technique and sharp dissection tonsillectomy...
- Factors associated with post-tonsillectomy hemorrhageP J Collison
Medical Clinic and Avera Sacred Heart Hospital, Yankton, SD 57078, USA
Ear Nose Throat J 79:640-2, 644, 646 passim. 2000..Although this technique is very effective in preventing primary hemorrhage, it does result in a deeper and more extensive zone of necrosis and the exposure of more and larger vessels when sloughing of the eschar occurs...
- Reduced risk of primary postoperative hemorrhage after tonsil surgery in Sweden: results from the National Tonsil Surgery Register in Sweden covering more than 10 years and 54,696 operationsAnne Charlotte Hessén Soderman
Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden
Laryngoscope 121:2322-6. 2011..To analyze the incidence of primary bleeding following tonsil surgery and to evaluate risk factors...
- Post-tonsillectomy hemorrhage: cold versus hot dissectionMichael S W Lee
Department of Otolaryngology, Ninewells Hospital and Medical School, Dundee, United Kingdom
Otolaryngol Head Neck Surg 131:833-6. 2004..the rate of reactionary and secondary posttonsillectomy hemorrhage using "cold" dissection and bipolar diathermy and to determine whether there was any difference in the postoperative hemorrhage rate between the 2 methods.
- Systematic review of delayed postoperative hemorrhage after pancreatic resectionDidier Roulin
Department of Visceral Surgery, University Hospital of Lausanne CHUV, Lausanne, Switzerland
J Gastrointest Surg 15:1055-62. 2011..This review assesses the presentation, management, and outcome of delayed postpancreatectomy hemorrhage (PPH) and suggests a novel algorithm as possible standard of care...
- Coblation tonsillectomy versus dissection tonsillectomy: postoperative hemorrhageAntonio Belloso
Department of Otolaryngology, Blackburn Royal Infirmary, UK
Laryngoscope 113:2010-3. 2003..The study aims to identify differences in reactionary and secondary hemorrhage proportions, comparing coblation with dissection tonsillectomy...
- Clinical investigation of upper gastrointestinal hemorrhage after percutaneous endoscopic gastrostomyShinji Nishiwaki
Department of Internal Medicine, Nishimino Kosei Hospital, and Department of Gastroenterology, Graduate School of Medicine, Gifu University, Gifu, Japan
Dig Endosc 22:180-5. 2010..Upper gastrointestinal (GI) hemorrhage after percutaneous endoscopic gastrostomy (PEG) is sometimes reported as one of the serious complications. Our purpose was to clarify the cause of upper GI hemorrhage after PEG...
- The coblation tonsillectomy learning curveA Simon Carney
The Department of Otolaryngology, Flinders Medical Centre, Adelaide, Australia
Otolaryngol Head Neck Surg 138:149-52. 2008..To establish if there is a learning curve for coblation tonsillectomy...
- Hemorrhagic complications from glaucoma surgery in patients on anticoagulation therapy or antiplatelet therapySimon K Law
Jules Stein Eye Institute, UCLA, Los Angeles, California 90095, USA
Am J Ophthalmol 145:736-746. 2008..To determine the incidence of and risk factors for hemorrhagic complications in patients on anticoagulation (ACT) or antiplatelet therapy (APT) having glaucoma surgery...
- Preoperative platelet inhibition with ASA does not influence postoperative blood loss following coronary artery bypass graftingH Gulbins
Department of Cardiovascular Surgery, University Heart Center at University Hospital Eppendorf, Hamburg, Germany
Thorac Cardiovasc Surg 57:18-21. 2009..This retrospective study reviews the results of over 10 000 patients with CABG, comparing continued platelet inhibition with preoperative disruption of this therapy...
- A prospective comparison of clamping the drain or post-operative salvage of blood in reducing blood loss after total knee arthroplastyN Tsumara
Hyogo Rehabilitation Center, 1070 Akebono cho Nishi ku, Kobe 651 2181, Japan
J Bone Joint Surg Br 88:49-53. 2006..Drain clamping with intra-articular injection of saline with adrenaline is more effective than post-operative autologous blood transfusion in reducing blood loss during total knee arthroplasty...
- Risk factors for bleeding after endoscopic submucosal dissection for gastric lesionsYosuke Tsuji
Department of Gastroenterology, Kanto Medical Center, NTT EC, 5 9 22 Higashi Gotanda, Shinagawa ku, Tokyo 141 8625, Japan
World J Gastroenterol 16:2913-7. 2010..To assess risk factors for bleeding after gastric endoscopic submucosal dissection (ESD) and to develop preventive measures...
- Harmonic scalpel tonsillectomy: a systematic review of evidence for postoperative hemorrhageCodruta Neumann
Department of ENT, Addenbrooke s Hospital, Cambridge, UK
Otolaryngol Head Neck Surg 137:378-84. 2007..To systematically review the literature on harmonic scalpel tonsillectomy with a view of comparing its postoperative hemorrhagic rate with the conventional methods for tonsillectomy...
- Outpatient thyroidectomy: experience in over 200 patientsMelanie W Seybt
Department of Otolaryngology Head and Neck Surgery, Medical College of Georgia, Augusta, Georgia, USA
Laryngoscope 120:959-63. 2010..An earlier favorable experience with outpatient surgery for a limited number of patients prompted our objective of an expanded evaluation of this practice...
- [Risk of hemorrhage after adenoidectomy and tonsillectomy. Value of the preoperative determination of partial thromboplastin time, prothrombin time and platelet count]K Scheckenbach
Klinik fur Hals, Nasen, Ohren Krankheiten, Medizinische Einrichtungen der Heinrich Heine Universität Düsseldorf, Moorenstrasse 5, 40225 Dusseldorf, Deutschland
HNO 56:312-20. 2008..hno.org/kollegen/gerinnung_te_ae.html ). The present study was undertaken to determine the occurrence of postoperative hemorrhage on the one hand, and the incidence of abnormal preoperative routine coagulation parameters or ..
- Does the risk of compressive hematoma after thyroidectomy authorize 1-day surgery?Pierre Leyre
Department of Endocrine Surgery, Jean Bernard Hospital, Poitiers University, 86021, Poitiers, France
Langenbecks Arch Surg 393:733-7. 2008..The aim of this study was to search for risk factors, in particular the use of anticoagulants or antiplatelet medication, and to see if the delay of hematoma formation would require 1-day surgery performed in a careful manner...
- Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trialChristoph Czarnetzki
Division of Anesthesiology, University Hospitals of Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
JAMA 300:2621-30. 2008..Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy...
- Fibrinolytic activity and bleeding after cardiac surgery with cardiopulmonary bypass and low-dose aprotinin therapyFrank Kuepper
Universitaetsklinik fuer Anaesthesiologie, Intensiv und Schmerztherapie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Bochum, Germany
Blood Coagul Fibrinolysis 14:147-53. 2003....
- Delayed release of drain in total knee replacement reduces blood loss. A prospective randomised studyNiloy Roy
Royal Oldham Hospital, Oldham, Lancashire, United Kingdom
Acta Orthop Belg 72:34-8. 2006..The results show that delaying release of the drains by one hour reduces postoperative blood loss and transfusion requirement following total knee arthroplasty...
- The risk associated with aprotinin in cardiac surgeryDennis T Mangano
Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
N Engl J Med 354:353-65. 2006..This approach appears counterintuitive to the accepted medical treatment of the same condition--namely, fibrinolysis to limit thrombosis. Despite this concern, no independent, large-scale safety assessment has been undertaken...
- [Coblation tonsillectomy. Results of a pilot study]J P Windfuhr
Klinik für Hals Nasen Ohren Heilkunde, Kopf, Hals und Plastische Gesichtschirurgie, Malteser Krankenhaus St Anna, Duisburg, Germany
HNO 54:190-7. 2006..The introduction of coblation tonsillectomy (CTE) may contribute to reduce the postoperative morbidity in terms of pain, delayed oral intake and bleeding...
- A comparison of aprotinin and lysine analogues in high-risk cardiac surgeryDean A Fergusson
Ottawa Health Research Institute, Ottawa, Canada
N Engl J Med 358:2319-31. 2008..We sought to determine whether aprotinin was superior to either tranexamic acid or aminocaproic acid in decreasing massive postoperative bleeding and other clinically important consequences...
- A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulcerationY Yamaguchi
The Third Department of Internal Medicine, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
Aliment Pharmacol Ther 21:111-5. 2005..However, uncertain whether an histamine2-receptor antagonist or proton-pump inhibitor is more effective...
- Effect of topical tranexamic acid in open heart surgeryA Abul-Azm
Department of Cardiothoracic Surgery, Cairo University, Kasr El Ainy Faculty of Medicine, Cairo, Egypt
Eur J Anaesthesiol 23:380-4. 2006..We have evaluated the effect of the topical use of tranexamic acid in the pericardial cavity on postoperative bleeding following open heart surgery...
- Aprotinin in cardiac surgeryVictor A Ferraris
N Engl J Med 354:1953-7; author reply 1953-7. 2006
- The role of histology and other risk factors for post-tonsillectomy haemorrhageA Schrock
Department of Otolaryngology, Head and Neck Surgery, University of Bonn, Bonn, Germany
Eur Arch Otorhinolaryngol 266:1983-7. 2009..Because a multifactorial aetiology of post-tonsillectomy haemorrhage has to be assumed, large multicenter studies are necessary to evaluate the significance of different risk factors...
- The value of phase 4 clinical testingGus J Vlahakes
N Engl J Med 354:413-5. 2006
- Aprotinin and lysine analogues in high-risk cardiac surgeryRobert J Porte
N Engl J Med 359:1181; author reply 1181-2. 2008
- Aprotinin in cardiac surgeryJeremiah R Brown
N Engl J Med 354:1953-7; author reply 1953-7. 2006
- Low-dose aspirin and clopidogrel: how to act in patients scheduled for day surgeryFrederique Servin
Department of Anaesthesia and Intensive Care, Bichat Hospital, Paris, France
Curr Opin Anaesthesiol 20:531-4. 2007..The purpose of this review is to examine the most recent findings and integrate them into the ambulatory surgery setting...
- Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysisJeffrey S Berger
Division of Cardiology, Duke University School of Medicine, Duke Clinical Research Institute, Durham, North Carolina 27705, USA
J Am Coll Cardiol 52:1693-701. 2008..S. hospitals...
- Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphismW Morawski
First Cardiac Surgery Department, Medical University of Silesia, Katowice, Poland
J Thorac Cardiovasc Surg 130:791-6. 2005..We also aimed to assess the effects of aspirin pretreatment and to ascertain the value of platelet function studies as predictors of postoperative bleeding...
- Costs of excessive postoperative hemorrhage in cardiac surgeryMichael C Christensen
Global Development, Novo Nordisk A S, Bagsvaerd, Denmark
J Thorac Cardiovasc Surg 138:687-93. 2009Excessive postoperative hemorrhage in cardiac surgery is a serious clinical complication placing substantial demands on hospital resources. This study quantifies the exact impact of postoperative hemorrhage on hospital costs in Germany.
- Effect of preoperative aspirin use in off-pump coronary artery bypass operationsArun K Srinivasan
Department of Cardiothoracic Surgery, Liverpool, United Kingdom
Ann Thorac Surg 76:41-5. 2003..We aimed to determine the effects of continuing aspirin therapy preoperatively...
- Aprotinin and lysine analogues in high-risk cardiac surgeryPaul S Myles
N Engl J Med 359:1181; author reply 1181-2. 2008
- Risk factors for bleeding after endoscopic mucosal resectionMasatsugu Shiba
Department of Gastroenterology, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
World J Gastroenterol 11:7335-9. 2005..To clarify the risk factors for bleeding after endoscopic mucosal resection (EMR)...
- Effects of recombinant factor VIIa in haemorrhagic complications of urological operationsGrazyna Michalska-Krzanowska
Department of Anaestahesiology and Intensive care Unit of the Clinical State Hospital No 2, Szczecin, Poland
Acta Haematol 109:158-60. 2003
- Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleedingA Mayo
Department of Surgery B, Sourasky Tel Aviv Medical Center, Tel Aviv, Israel
Vox Sang 87:34-40. 2004..A protocol for its use in acute, uncontrolled life-threatening bleeding, was devised and employed. A haematologist/transfusion specialist was assigned as a member of the team...
- Bloodless medicine: clinical care without allogeneic blood transfusionLawrence T Goodnough
Washington University School of Medicine, St Louis, Missouri, USA
Transfusion 43:668-76. 2003
- Reduced levels of fibrin (antithrombin I) and antithrombin III underlie coagulopathy following complex cardiac surgeryRoman M Sniecinski
Blood Coagul Fibrinolysis 19:178-9. 2008
- Successful treatment with recombinant factor VIIa for intractable bleeding at pelvic surgeryJarosław Daniloś
First Department of Gynecology, Medical University, Lublin, Poland
Obstet Gynecol 101:1172-3. 2003..Postoperative bleeding may be complicated by failure to identify the site of bleeding, multiple bleeding points, and persistent hemorrhage despite surgical intervention...
- Use of recombinant activated factor VII concentrate to control postoperative hemorrhage in complex cardiovascular surgeryLyndsey J Bowman
Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Ann Thorac Surg 85:1669-76; discussion 1676-7. 2008Complex cardiovascular surgery often results in postoperative hemorrhage. Excessive blood product use may cause systemic thrombosis, end-organ dysfunction, and edema preventing chest closure...
- Management of delayed postoperative hemorrhage after pancreaticoduodenectomy: a meta-analysisPaolo Limongelli
HPB Unit, Division of Surgery and Intensive Care, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London, England
Arch Surg 143:1001-7; discussion 1007. 2008To determine whether interventional radiology (IR) or laparotomy (LAP) is the best management of delayed postoperative hemorrhage (DPH) after pancreaticoduodenectomy...
- A case of hepatic artery embolization and partial arterialization of the portal vein for intraperitoneal, hemorrhage after a pancreaticoduodenectomyKenichi Teramoto
Department of Surgery, Division of Hepato Biliary Pancreatic Surgery, Tokyo Medical and Dental University, Yushima 1 5 45, Bunkyo ku, Tokyo, Japan
Hepatogastroenterology 50:1217-9. 2003..Whether the partial portal vein arterialization was effective is unclear, but partial portal vein arterialization should be considered as an option in cases of total hepatic artery occlusion with impairment of portal blood flow...
- The effect of preoperative clopidogrel on bleeding after coronary artery bypass surgeryWade Kang
Department of Surgery, St Luke s Hospital and Health Network, Bethlehem, Pennsylvania 18015, USA
J Surg Educ 64:88-92. 2007..The purpose of this study was to analyze the effect of preoperative clopidogrel exposure on bleeding complications, blood transfusions requirements, and reoperations in patients undergoing coronary artery bypass grafting (CABG)...
- Postoperative bypass bleeding: a bypass-associated dilutional (BAD) coagulopathy?Brian S Bull
School of Medicine, Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA 92350, USA
Blood Cells Mol Dis 43:256-9. 2009..The presence of un-neutralized protamine combined with critically lowered clotting factors leads to marked coagulopathy...
- Recombinant activated factor VII in cardiac surgery: a meta-analysisAlberto Zangrillo
Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia
J Cardiothorac Vasc Anesth 23:34-40. 2009..Few trials have investigated rFVIIa and each individually lacked power to detect a beneficial effect on transfusion of blood products or thromboembolic side effects...
- Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery: a review and meta-analysis of published dataChristian von Heymann
Department of Anesthesiology and Intensive Care Medicine, Charite University Medicine Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Augustenburger Platz 1, 13353 Berlin, Germany
Crit Care 12:R14. 2008..The purpose of this study was to determine the role of recombinant activated factor VII (rFVIIa) in abdominal, vascular, and urological surgery...
- Recombinant activated factor vii to control massive post operative bleeding after septic aortobifemoral graftingM Raux
Eur J Anaesthesiol 22:805-7. 2005
- The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysisDavid Henry
School of Medicine and Public Health, University of Newcastle, Australia
CMAJ 180:183-93. 2009..Because of recent concerns about the safety of aprotinin, we updated our 2007 Cochrane review that compared the relative benefits and risks of aprotinin and the lysine analogues tranexamic acid and epsilon aminocaproic acid...
- Delayed massive arterial hemorrhage after pancreaticoduodenectomy for cancer. Management of a life-threatening complicationRoberto Santoro
Department of Oncological Surgery, Regina Elena Cancer Institute of Rome, Italy
Hepatogastroenterology 50:2199-204. 2003..The purpose of this study was to define diagnostic and treatment methodologies to maximize survival...
- Albumin versus hydroxyethyl starch in cardiopulmonary bypass surgery: a meta-analysis of postoperative bleedingM M Wilkes
Hygeia Associates, Grass Valley, California 95949, USA
Ann Thorac Surg 72:527-33; discussion 534. 2001..This meta-analysis tested the hypothesis that cumulative blood loss during the first 24 hours after cardiopulmonary bypass is lower in patients exposed to albumin than hydroxyethyl starch (HES)...
- Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot studyMartin Karlsson
Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
Thromb Haemost 102:137-44. 2009..Larger studies are necessary to ensure safety and confirm efficacy of prophylactic fibrinogen treatment in cardiac surgery...
- Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgeryRavi Gill
Cardiac Anaesthesia and Intensive Care Medicine, Southampton University Hospitals, Southampton, UK
Circulation 120:21-7. 2009..Our objective was to investigate the safety and possible benefits of rFVIIa in patients who bleed after cardiac surgery...
- Low-dose recombinant factor VIIa in the management of uncontrolled postoperative hemorrhage in cardiac surgery patientsEwoudt M W van de Garde
Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
J Cardiothorac Vasc Anesth 20:573-5. 2006
- Management of early hemorrhage from pancreatic anastomoses after pancreaticoduodenectomyMoritz N Wente
Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, DE 69120 Heidelberg, Germany
Dig Surg 23:203-8. 2006..The leading cause of emergency reexploration is early postoperative hemorrhage due to technical failure of hemostasis...
- Novel approach to bleeding in patients undergoing cardiac surgery with liver dysfunctionR G Stuklis
Department of Cardiothoracic Surgery and Haematology, Southampton General Hospital, Southampton, UK
Eur J Cardiothorac Surg 19:219-20. 2001..We describe two patients with significant liver dysfunction (Child--Pugh class B) who underwent cardiac surgery at our institution facilitated by the use of a prothrombin complex concentrate for the management of postoperative bleeding...
- Delayed re-exploration for bleeding after coronary artery bypass surgery results in adverse outcomesCliff K Choong
Papworth Hospital NHS Trust, Cambridge, United Kingdom
Eur J Cardiothorac Surg 31:834-8. 2007..We aimed to identify the impact of re-exploration for bleeding after coronary artery bypass grafting (CABG) and the effect of time delay, re-exploration within 12h (<12h) versus 12h or later (>or=12h)...
- Endovascular treatment of hemorrhage after tonsillectomy in childrenM J Opatowsky
Department of Radiological Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
AJNR Am J Neuroradiol 22:713-6. 2001..We report two cases of hemorrhage after tonsillectomy and/or adenoidectomy and describe the endovascular management of this complication in children...
- Early postoperative hemorrhage after open and laparoscopic roux-en-y gastric bypassCharles Bakhos
Department of Surgery, Hospital of Saint Raphael, MOB 315, 1450 Chapel Street, New Haven, CT 06511, USA
Obes Surg 19:153-7. 2009Early postoperative hemorrhage is an infrequent complication of both laparoscopic and open Roux-en-Y gastric bypass (RYGBP)...
- Successful treatment of severe intra-abdominal bleeding associated with disseminated intravascular coagulation using recombinant activated factor VIIF Moscardo
Department of Haematology, Hospital Universitario La Fe, Valencia, Spain
Br J Haematol 114:174-6. 2001..No side-effects related to rFVIIa were noted. This case suggests a potential role for rFVIIa in the treatment of severe and refractory bleeding associated with DIC...
- Correlation of perioperative platelet function and coagulation tests with bleeding after cardiopulmonary bypass surgeryRoger C Carroll
Department of Anesthesiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee 37920, USA
J Lab Clin Med 147:197-204. 2006..In three cases without negative surgery parameters, coagulation dysfunction was observed. The remaining five cases did not give a clear indication of which parameters were primarily responsible for the bleeding...
- Management of pelvic hemorrhageR S Tomacruz
Department of Gynecology and Obstetrics The Johns Hopkins Hospital and Medical Institutions, Baltimore, Maryland 21287, USA
Surg Clin North Am 81:925-48. 2001....
- Stroke Hospitalization in the Elderly with Medicare FFSJudith Lichtman; Fiscal Year: 2009..These results will help inform decisions about the allocation of adequate resources, and more importantly, help identify opportunities to improve care and prevention of elderly stroke patients. ..
- Effect of lipid modification on peripheral arterial disease (PAD)Christie Ballantyne; Fiscal Year: 2007..Finally, these studies will advance our understanding of the molecular mechanisms of inflammation and thrombosis associated with aggressive lipid modification. ..
- OU Developmental Center for Injury Prevention ResearchGary Raskob; Fiscal Year: 2005..abstract_text> ..
- World Workshop in Oral Medicine IVPeter Lockhart; Fiscal Year: 2005..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..
- Hospital Integration and Medicare Reimbursement PolicyDaniel Kessler; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- ICOS-B7h in Islet Transplant Rejection and AutoimmunityAndrew Shapiro; Fiscal Year: 2004....
- Impact of Aging on Stroke Care: A National PerspectiveJudith Lichtman; Fiscal Year: 2004..We hypothesize that variations in care exist by age. Moreover, these differences in care will not be explained by differences clinical features or co-morbid conditions associated with aging. ..
- PHARMACOGENETICS IN SURGICAL CRITICAL CAREBradley Freeman; Fiscal Year: 2004..The environment for this project is Washington University School of Medicine, an institution with access to a large clinical volume and established expertise in genomic research. ..
- OU Human Research Protection Program, Year 2Gary Raskob; Fiscal Year: 2003..The University of Oklahoma is committed to maintaining these initiatives after the term of this award. ..
- Reducing Sedative Exposure in Ventilated ICU PatientsLinda Chlan; Fiscal Year: 2009..abstract_text> ..
- Insulin Resistance and Adenomas of the ColorectumTheodore Levin; Fiscal Year: 2003..abstract_text> ..
- TRIAL OF ANTI-TNF ALPHA IN ISLET TRANSPLANTATIONAndrew Shapiro; Fiscal Year: 2002....
- Improving use of peri-operative beta-blockers with a multidimentional QI programAndrew Auerbach; Fiscal Year: 2009..The impact of this set of tools will be substantial as groups such as the NSQIP, SCIP, National Quality Forum, and Leapfrog Group continue to endorse PBB as a key strategy to reduce surgical morbidity and mortality. ..
- Angiogenesis and Cardiac Growth as Heart Failure TherapyY Woo; Fiscal Year: 2008..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
- Endothelial progenitor cells and surgical outcomesAndrew Auerbach; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Nanostenting Hydrogels for Sinus SurgeryRICHARD ORLANDI; Fiscal Year: 2004..The results of these Phase I studies will determine the feasibility and the optimal chemical properties of a nanostenting HA gel for human trials. ..
- Bacteremia from Dental Extraction vs. Oral HygienePeter Lockhart; Fiscal Year: 2004..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
- GLOBAL ANALYSIS OF TECHNOLOGICAL CHANGE IN HEALTH CAREDaniel Kessler; Fiscal Year: 2002..abstract_text> ..
- SLC2A9, A Candidate ER GLUT in Normal and Cancer CellsJeffrey Moley; Fiscal Year: 2002..Identification of SLC2A9 as the endoplasmic reticulum glucose transporter will improve understanding of GSDs, and of glucose metabolism in benign and malignant tissues. ..