postoperative hemorrhage

Summary

Summary: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.

Top Publications

  1. ncbi Hemorrhage following tonsillectomy and adenoidectomy in 15,218 patients
    J P Windfuhr
    Department of Otorhinolaryngology, Plastic Head and Neck Surgery, St Anna Hospital, Duisburg, Germany
    Otolaryngol Head Neck Surg 132:281-6. 2005
  2. ncbi Technical feasibility of endoscopic submucosal dissection for early gastric cancer in patients taking anti-coagulants or anti-platelet agents
    S Ono
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo, Tokyo 113 8655, Japan
    Dig Liver Dis 41:725-8. 2009
  3. ncbi Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?
    Paul Zufferey
    Department of Anesthesiology and Intensive Care and EA3065, Thrombosis Research Group, University Hospital of Saint Etienne, Saint Etienne, France
    Anesthesiology 105:1034-46. 2006
  4. ncbi False aneurysm of the sphenopalatine artery after a Le Fort I osteotomy: report of 2 cases
    Olindo Procopio
    Department of Maxillofacial Surgery, University of Padova Medical and Dental School, Padova, Italy
    J Oral Maxillofac Surg 61:520-4; discussion 524-5. 2003
  5. ncbi Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement
    L Good
    Department of Orthopaedics, Faculty of Health Sciences, University of Linkoping, Sweden
    Br J Anaesth 90:596-9. 2003
  6. ncbi Use of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical procedures
    Heather J Ipema
    Drug Information Group, University of Illinois at Chicago, Chicago, IL, USA
    Ann Pharmacother 46:97-107. 2012
  7. ncbi Increased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: implications of a prospective study
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Stroke 33:1618-23. 2002
  8. ncbi The aprotinin story--is BART the final chapter?
    Wayne A Ray
    N Engl J Med 358:2398-400. 2008
  9. ncbi Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial
    Jean Wong
    Department of Anesthesia, Toronto Western Hospital, University of Toronto, 2MC 434, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
    J Bone Joint Surg Am 92:2503-13. 2010
  10. ncbi Hidden blood loss after surgery for hip fracture
    N B Foss
    Hvidovre University Hospital, Copenhagen, Denmark
    J Bone Joint Surg Br 88:1053-9. 2006

Research Grants

Detail Information

Publications243 found, 100 shown here

  1. ncbi Hemorrhage following tonsillectomy and adenoidectomy in 15,218 patients
    J P Windfuhr
    Department of Otorhinolaryngology, Plastic Head and Neck Surgery, St Anna Hospital, Duisburg, Germany
    Otolaryngol Head Neck Surg 132:281-6. 2005
    ..To evaluate potential risk factors and the incidence of bleeding following adenoidectomy or tonsillectomy, with or without adenoidectomy requiring surgical treatment under general anesthesia...
  2. ncbi Technical feasibility of endoscopic submucosal dissection for early gastric cancer in patients taking anti-coagulants or anti-platelet agents
    S Ono
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo, Tokyo 113 8655, Japan
    Dig Liver Dis 41:725-8. 2009
    ..Anti-coagulants and anti-platelet agents are widely used, especially in elderly patients, to prevent thromboembolic disease. However, the feasibility of endoscopic submucosal dissection for such patients has not been investigated...
  3. ncbi Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?
    Paul Zufferey
    Department of Anesthesiology and Intensive Care and EA3065, Thrombosis Research Group, University Hospital of Saint Etienne, Saint Etienne, France
    Anesthesiology 105:1034-46. 2006
    ..Although the results suggest that aprotinin and tranexamic acid significantly reduce allogeneic erythrocyte transfusion, further evaluation of safety is required before recommending the use of antifibrinolytics in orthopedic surgery...
  4. ncbi False aneurysm of the sphenopalatine artery after a Le Fort I osteotomy: report of 2 cases
    Olindo Procopio
    Department of Maxillofacial Surgery, University of Padova Medical and Dental School, Padova, Italy
    J Oral Maxillofac Surg 61:520-4; discussion 524-5. 2003
  5. ncbi Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement
    L Good
    Department of Orthopaedics, Faculty of Health Sciences, University of Linkoping, Sweden
    Br J Anaesth 90:596-9. 2003
    ..Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known...
  6. ncbi Use of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical procedures
    Heather J Ipema
    Drug Information Group, University of Illinois at Chicago, Chicago, IL, USA
    Ann Pharmacother 46:97-107. 2012
    ..To evaluate the literature describing topical use of tranexamic acid or aminocaproic acid for prevention of postoperative bleeding after major surgical procedures...
  7. ncbi Increased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: implications of a prospective study
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Stroke 33:1618-23. 2002
    ..The objective of this prospective study was to determine the incidence and clinical relevance of perioperative decreased factor XIII with respect to standard coagulation parameters and the occurrence of postoperative hematoma...
  8. ncbi The aprotinin story--is BART the final chapter?
    Wayne A Ray
    N Engl J Med 358:2398-400. 2008
  9. ncbi Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial
    Jean Wong
    Department of Anesthesia, Toronto Western Hospital, University of Toronto, 2MC 434, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
    J Bone Joint Surg Am 92:2503-13. 2010
    ..The objective of the present trial was to assess the efficacy and safety of the topical application of tranexamic acid on postoperative blood loss in patients undergoing primary unilateral total knee arthroplasty with cement...
  10. ncbi Hidden blood loss after surgery for hip fracture
    N B Foss
    Hvidovre University Hospital, Copenhagen, Denmark
    J Bone Joint Surg Br 88:1053-9. 2006
    ..We conclude that total blood loss after surgery for hip fracture is much greater than that observed intra-operatively. Frequent post-operative measurements of haemoglobin are necessary to avoid anaemia...
  11. ncbi Relationship between factor XIII activity, fibrinogen, haemostasis screening tests and postoperative bleeding in cardiopulmonary bypass surgery
    Markus Blome
    Clinic for Cardiac Surgery, Institute of Hemostaseology, Academic City Hospital, D 67063 Ludwigshafen, Germany
    Thromb Haemost 93:1101-7. 2005
    ..There is however an inverse association between preoperative or postoperative plasma fibrinogen levels and postoperative bleeding. These findings indicate a modulation of postoperative bleeding by fibrinogen levels...
  12. ncbi Visceral artery pseudoaneurysms following pancreatoduodenectomy
    Eseroghene Otah
    Department of Surgery, Our Lady of Mercy Medical Center, Bronx, NY, USA
    Arch Surg 137:55-9. 2002
    ..These patients all had "herald" bleeding from their abdominal drains. Subsequent angiography and therapeutic embolizations were successfully performed...
  13. ncbi Effect of clopidogrel on bleeding and transfusions after off-pump coronary artery bypass graft surgery: impact of discontinuation prior to surgery
    Simon Maltais
    Department of Cardiac Surgery, CHUM Hopital Notre Dame, Montreal, QC, Canada
    Eur J Cardiothorac Surg 34:127-31. 2008
    ..We evaluated the effect of aspirin and clopidogrel (CPDG), both irreversible platelet aggregation inhibitors, on operative bleeding and determined the optimal timing for their discontinuation before surgery...
  14. ncbi Risk factors for complications of endoscopic submucosal dissection in gastric tumors: analysis of 478 lesions
    Kotaro Mannen
    Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, 5 1 1 Nabeshima, Saga 849 8501, Japan
    J Gastroenterol 45:30-6. 2010
    ..Endoscopic submucosal dissection (ESD) technique has facilitated en bloc removal of widely spread lesions from the stomach. This retrospective study aimed to determine factors associated with serious complications of ESD...
  15. ncbi Delayed hemorrhage after pancreaticoduodenectomy
    Seong Ho Choi
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea South Korea
    J Am Coll Surg 199:186-91. 2004
    b>Postoperative hemorrhage, particularly delayed hemorrhage after pancreaticoduodenectomy, is a serious complication and one of the most common causes of mortality after pancreaticoduodenectomy.
  16. ncbi Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients
    A Bergenfelz
    Scandanavian Quality Register for Thyroid and Parathyroid Surgery, Lund, Sweden
    Langenbecks Arch Surg 393:667-73. 2008
    ..During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce...
  17. ncbi Chemoprophylaxis without intra-articular wound drainage can replace autotransfusion in primary TKA
    Hervé Hourlier
    Department of Orthopedic Surgery, Polyclinique de la Thiérache, Wignehies, France
    Orthopedics 34:154. 2011
    ..Chemoprophylaxis proved superior to reinfusion at decreasing blood transfusion requirements in the routine daily setting of unilateral cemented primary TKA...
  18. pmc Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplasty
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami, Ami Machi, Inashiki Gun, Ibaraki 300 0394, Japan
    J Orthop Surg Res 7:32. 2012
    ..In a retrospective study, we explored whether postoperative intra-articular retrograde injection of tranexamic acid (TA) and leaving a drain clamp in place for 1 h reduced blood loss...
  19. ncbi [Dabigatran therapy--perioperative management and interpretation of coagulation tests]
    M Spannagl
    Haemostaseologie Campus Innenstadt, Klinikum der Universitat Munchen, Munchen, Germany
    Hamostaseologie 32:294-305. 2012
    ..A distinct feature of dabigatran is the possibility of effectively removing dabigatran from the circulation by haemodialysis...
  20. pmc Dabigatran in patients with atrial fibrillation: perioperative and periinterventional management
    A Weltermann
    Department of Medicine I, Elisabethinen Hospital Linz, Fadinger Straße 1, 4020, Linz, Austria
    Wien Klin Wochenschr 124:340-7. 2012
    ....
  21. ncbi Pseudoaneurysm of the facial artery as a late complication of bilateral sagittal split osteotomy and facial trauma
    Mansoor Madani
    Department of Oral and Maxillofacial Surgery, Capital Health System, Trenton, New Jersey, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:579-84. 2010
    ....
  22. pmc Efficient strategy for controlling postoperative hemorrhage in total knee arthroplasty
    Hideyuki Sasanuma
    Department of Orthopaedic Surgery, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, 3290498, Japan
    Knee Surg Sports Traumatol Arthrosc 19:921-5. 2011
    ....
  23. ncbi Is nasal packing necessary after septoplasty? A meta-analysis
    Sarfaraz M Banglawala
    Otolaryngology Head and Neck Surgery, McMaster University, Hamilton, Ontario, Canada
    Int Forum Allergy Rhinol 3:418-24. 2013
    ..The purpose of this work was to perform a meta-analysis on the existing literature to evaluate the role of nasal packing after septoplasty...
  24. ncbi Unusual late vascular complications of sagittal split osteotomy of the mandibular ramus
    Jui Pin Lai
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital in Kaohsiung, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
    J Craniofac Surg 16:664-8. 2005
    ..Awareness of the possible late vascular complications to facilitate early detection and management is also important...
  25. pmc Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients
    Rajesh N Maniar
    Department of Orthopaedic Surgery, Lilavati Hospital and Research Centre, A 791, Bandra Reclamation, Bandra W, Mumbai 400050, India
    Clin Orthop Relat Res 470:2605-12. 2012
    ..The antifibrinolytic tranexamic acid reduces surgical blood loss, but studies have not identified an optimal regimen...
  26. ncbi FloSeal use in endoscopic sinus surgery: effect on postoperative bleeding and synechiae formation
    Mark Jameson
    Department of Otolaryngology Head and Neck Surgery, University of Virginia Health System, Charlottesville, VA, USA
    Am J Otolaryngol 27:86-90. 2006
    ..The objective of this study is to evaluate the effect of the hemostatic agent, FloSeal (FS), on bleeding and healing after functional endoscopic sinus surgery...
  27. ncbi Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing
    Konrad G Kastl
    Department of Otorhinolaryngology, University Hospital Ulm, University of Ulm, Germany
    Eur Arch Otorhinolaryngol 266:1239-43. 2009
    ..In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design...
  28. ncbi Anesthesia for intranasal surgery: a comparison between tracheal intubation and the flexible reinforced laryngeal mask airway
    A C Webster
    Department of Anaesthesia, St Joseph s Health Centre, University of Western Ontario, London, Canada
    Anesth Analg 88:421-5. 1999
    ..There were no significant differences in the incidence of airway complications between Groups II and III...
  29. pmc Factors associated with excessive bleeding in cardiopulmonary bypass patients: a nested case-control study
    Juan J Jimenez Rivera
    Intensive Care Unit, University Hospital of Canary Islands, La Laguna, Spain
    J Cardiothorac Surg 2:17. 2007
    ..Less than 50% of patients undergoing re-intervention exhibit surgical sources of bleeding. We studied clinical and genetic factors associated with EB...
  30. ncbi 15-year audit of post-tonsillectomy haemorrhage at Dunedin Hospital
    Emily A Macassey
    Department of Otorhinolaryngology, Head and Neck Surgery, Dunedin Public Hospital, and Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    ANZ J Surg 77:579-82. 2007
    ..3% (P<0.0001, 95% confidence interval 8.5-22.5%). The increase is coincidental with the change-over to predominant diathermy technique and a routine use of postoperative non-steroidal anti-inflammatory drugs and steroids...
  31. ncbi Migration of steel-wire coils into the stomach after transcatheter arterial embolization for a bleeding splenic artery pseudoaneurysm: report of a case
    T Takahashi
    Department of Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan
    Surg Today 31:458-62. 2001
    ..By occluding the PSA in this way, the subsequent migration of steel-wire coils into the pseudocyst and stomach might have been prevented in our patient...
  32. ncbi Nonsteroidal antiinflammatory drugs and the risk of operative site bleeding after tonsillectomy: a quantitative systematic review
    Steen Møiniche
    Department of Anesthesiology and Intensive Care Medicine, Herlev University Hospital, Copenhagen, Denmark
    Anesth Analg 96:68-77, table of contents. 2003
    ..83) and number-needed-to-treat, 60 (95% CI, 34-277). Compared with opioids, NSAIDs were equianalgesic, and the risk of emesis was significantly decreased (relative risk, 0.73; 95% CI, 0.63-0.85; numbers-needed-to-treat, 9; 95% CI, 5-19)...
  33. ncbi Incidence of post-tonsillectomy hemorrhage in children and adults: a study of 4,848 patients
    Jochen P Windfuhr
    Department of Otorhinolaryngology Plastic Head and Neck Surgery, St Anna Hospital, 47259 Duisburg, Albertus Magnus Str 33, Germany
    Ear Nose Throat J 81:626-8, 630, 632 passim. 2002
    ..Awareness of these risk factors should help improve patient care and outcomes...
  34. ncbi Diagnostic computed tomographic angiography and therapeutic emergency transcatheter arterial embolization for management of postoperative hemorrhage after gynecologic laparoscopic surgery
    Akihiro Takeda
    Department of Obstetrics and Gynecology, Gifu Prefectural Tajimi Hospital, Gifu, Japan
    J Minim Invasive Gynecol 15:332-41. 2008
    ..To evaluate the diagnostic value of 3-dimensional computed tomographic (CT) angiography and treatment efficacy of emergency transcatheter arterial embolization (TAE) for early postoperative hemorrhage after gynecologic laparoscopic surgery.
  35. ncbi [Spectrum and bleeding complications of sonographically guided interventions of the liver and pancreas]
    M Frieser
    Medizinische Klinik 1, NOZ, Universitat Erlangen Nurnberg, Ulmenweg 18, Erlangen
    Ultraschall Med 30:168-74. 2009
    ..Interventions with needles with a larger diameter seem to cause more complications. In search of potential complications, we examined 1923 sonographically guided interventions of the liver and pancreas in a retrospective analysis...
  36. ncbi Review and application of serine protease inhibition in coronary artery bypass graft surgery
    Laura Engles
    School of Pharmacy, University of Connecticut, 69 North Eagleville Road, Unit 3092, Storrs, CT 06269 3092, USA
    Am J Health Syst Pharm 62:S9-14. 2005
    ..These responses are largely mediated by serine proteases such as kallikrein, thrombin, and plasmin...
  37. ncbi Dexamethasone and tonsillectomy bleeding: a meta-analysis
    Alon Geva
    Department of Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Otolaryngol Head Neck Surg 144:838-43. 2011
    ..To use meta-analytic techniques to examine the effect of dexamethasone on the risk of postoperative bleeding following tonsillectomy...
  38. ncbi Platelet-dense granule deficiency causes postoperative hemorrhage in patients receiving enoxaparin: a novel observation with dramatic clinical implications
    Mark D Kligman
    Department of Surgery, University of Maryland, Baltimore, MD 21201 1595, USA
    Am J Surg 197:365-70. 2009
    ..We hypothesized that administration of LMWH may unmask latent platelet dysfunction and result in postoperative hemorrhage.
  39. ncbi The effect of preoperative dexamethasone on early oral intake, vomiting and pain after tonsillectomy
    M Nil Kaan
    Adnan Menderes University, School of Medicine, Department of Anesthesiology and Reanimation, 09100 Aydin, Turkey
    Int J Pediatr Otorhinolaryngol 70:73-9. 2006
    ..5 mg/kg i.v. dexamethasone on postoperative early oral intake, pain, vomiting in patients undergoing adenotonsillectomy while performing standard anesthesia technique and sharp dissection tonsillectomy...
  40. ncbi Factors associated with post-tonsillectomy hemorrhage
    P J Collison
    Medical Clinic and Avera Sacred Heart Hospital, Yankton, SD 57078, USA
    Ear Nose Throat J 79:640-2, 644, 646 passim. 2000
    ..Although this technique is very effective in preventing primary hemorrhage, it does result in a deeper and more extensive zone of necrosis and the exposure of more and larger vessels when sloughing of the eschar occurs...
  41. ncbi Reduced risk of primary postoperative hemorrhage after tonsil surgery in Sweden: results from the National Tonsil Surgery Register in Sweden covering more than 10 years and 54,696 operations
    Anne Charlotte Hessén Soderman
    Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden
    Laryngoscope 121:2322-6. 2011
    ..To analyze the incidence of primary bleeding following tonsil surgery and to evaluate risk factors...
  42. ncbi Post-tonsillectomy hemorrhage: cold versus hot dissection
    Michael S W Lee
    Department of Otolaryngology, Ninewells Hospital and Medical School, Dundee, United Kingdom
    Otolaryngol Head Neck Surg 131:833-6. 2004
    ..the rate of reactionary and secondary posttonsillectomy hemorrhage using "cold" dissection and bipolar diathermy and to determine whether there was any difference in the postoperative hemorrhage rate between the 2 methods.
  43. ncbi Systematic review of delayed postoperative hemorrhage after pancreatic resection
    Didier Roulin
    Department of Visceral Surgery, University Hospital of Lausanne CHUV, Lausanne, Switzerland
    J Gastrointest Surg 15:1055-62. 2011
    ..This review assesses the presentation, management, and outcome of delayed postpancreatectomy hemorrhage (PPH) and suggests a novel algorithm as possible standard of care...
  44. ncbi Coblation tonsillectomy versus dissection tonsillectomy: postoperative hemorrhage
    Antonio Belloso
    Department of Otolaryngology, Blackburn Royal Infirmary, UK
    Laryngoscope 113:2010-3. 2003
    ..The study aims to identify differences in reactionary and secondary hemorrhage proportions, comparing coblation with dissection tonsillectomy...
  45. ncbi Clinical investigation of upper gastrointestinal hemorrhage after percutaneous endoscopic gastrostomy
    Shinji Nishiwaki
    Department of Internal Medicine, Nishimino Kosei Hospital, and Department of Gastroenterology, Graduate School of Medicine, Gifu University, Gifu, Japan
    Dig Endosc 22:180-5. 2010
    ..Upper gastrointestinal (GI) hemorrhage after percutaneous endoscopic gastrostomy (PEG) is sometimes reported as one of the serious complications. Our purpose was to clarify the cause of upper GI hemorrhage after PEG...
  46. ncbi The coblation tonsillectomy learning curve
    A Simon Carney
    The Department of Otolaryngology, Flinders Medical Centre, Adelaide, Australia
    Otolaryngol Head Neck Surg 138:149-52. 2008
    ..To establish if there is a learning curve for coblation tonsillectomy...
  47. ncbi Hemorrhagic complications from glaucoma surgery in patients on anticoagulation therapy or antiplatelet therapy
    Simon K Law
    Jules Stein Eye Institute, UCLA, Los Angeles, California 90095, USA
    Am J Ophthalmol 145:736-746. 2008
    ..To determine the incidence of and risk factors for hemorrhagic complications in patients on anticoagulation (ACT) or antiplatelet therapy (APT) having glaucoma surgery...
  48. ncbi Preoperative platelet inhibition with ASA does not influence postoperative blood loss following coronary artery bypass grafting
    H Gulbins
    Department of Cardiovascular Surgery, University Heart Center at University Hospital Eppendorf, Hamburg, Germany
    Thorac Cardiovasc Surg 57:18-21. 2009
    ..This retrospective study reviews the results of over 10 000 patients with CABG, comparing continued platelet inhibition with preoperative disruption of this therapy...
  49. ncbi A prospective comparison of clamping the drain or post-operative salvage of blood in reducing blood loss after total knee arthroplasty
    N Tsumara
    Hyogo Rehabilitation Center, 1070 Akebono cho Nishi ku, Kobe 651 2181, Japan
    J Bone Joint Surg Br 88:49-53. 2006
    ..Drain clamping with intra-articular injection of saline with adrenaline is more effective than post-operative autologous blood transfusion in reducing blood loss during total knee arthroplasty...
  50. pmc Risk factors for bleeding after endoscopic submucosal dissection for gastric lesions
    Yosuke Tsuji
    Department of Gastroenterology, Kanto Medical Center, NTT EC, 5 9 22 Higashi Gotanda, Shinagawa ku, Tokyo 141 8625, Japan
    World J Gastroenterol 16:2913-7. 2010
    ..To assess risk factors for bleeding after gastric endoscopic submucosal dissection (ESD) and to develop preventive measures...
  51. ncbi Harmonic scalpel tonsillectomy: a systematic review of evidence for postoperative hemorrhage
    Codruta Neumann
    Department of ENT, Addenbrooke s Hospital, Cambridge, UK
    Otolaryngol Head Neck Surg 137:378-84. 2007
    ..To systematically review the literature on harmonic scalpel tonsillectomy with a view of comparing its postoperative hemorrhagic rate with the conventional methods for tonsillectomy...
  52. ncbi Outpatient thyroidectomy: experience in over 200 patients
    Melanie W Seybt
    Department of Otolaryngology Head and Neck Surgery, Medical College of Georgia, Augusta, Georgia, USA
    Laryngoscope 120:959-63. 2010
    ..An earlier favorable experience with outpatient surgery for a limited number of patients prompted our objective of an expanded evaluation of this practice...
  53. ncbi [Risk of hemorrhage after adenoidectomy and tonsillectomy. Value of the preoperative determination of partial thromboplastin time, prothrombin time and platelet count]
    K Scheckenbach
    Klinik fur Hals, Nasen, Ohren Krankheiten, Medizinische Einrichtungen der Heinrich Heine Universität Düsseldorf, Moorenstrasse 5, 40225 Dusseldorf, Deutschland
    HNO 56:312-20. 2008
    ..hno.org/kollegen/gerinnung_te_ae.html ). The present study was undertaken to determine the occurrence of postoperative hemorrhage on the one hand, and the incidence of abnormal preoperative routine coagulation parameters or ..
  54. ncbi Does the risk of compressive hematoma after thyroidectomy authorize 1-day surgery?
    Pierre Leyre
    Department of Endocrine Surgery, Jean Bernard Hospital, Poitiers University, 86021, Poitiers, France
    Langenbecks Arch Surg 393:733-7. 2008
    ..The aim of this study was to search for risk factors, in particular the use of anticoagulants or antiplatelet medication, and to see if the delay of hematoma formation would require 1-day surgery performed in a careful manner...
  55. ncbi Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial
    Christoph Czarnetzki
    Division of Anesthesiology, University Hospitals of Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    JAMA 300:2621-30. 2008
    ..Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy...
  56. ncbi Fibrinolytic activity and bleeding after cardiac surgery with cardiopulmonary bypass and low-dose aprotinin therapy
    Frank Kuepper
    Universitaetsklinik fuer Anaesthesiologie, Intensiv und Schmerztherapie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Bochum, Germany
    Blood Coagul Fibrinolysis 14:147-53. 2003
    ....
  57. ncbi Delayed release of drain in total knee replacement reduces blood loss. A prospective randomised study
    Niloy Roy
    Royal Oldham Hospital, Oldham, Lancashire, United Kingdom
    Acta Orthop Belg 72:34-8. 2006
    ..The results show that delaying release of the drains by one hour reduces postoperative blood loss and transfusion requirement following total knee arthroplasty...
  58. ncbi The risk associated with aprotinin in cardiac surgery
    Dennis T Mangano
    Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
    N Engl J Med 354:353-65. 2006
    ..This approach appears counterintuitive to the accepted medical treatment of the same condition--namely, fibrinolysis to limit thrombosis. Despite this concern, no independent, large-scale safety assessment has been undertaken...
  59. ncbi [Coblation tonsillectomy. Results of a pilot study]
    J P Windfuhr
    Klinik für Hals Nasen Ohren Heilkunde, Kopf, Hals und Plastische Gesichtschirurgie, Malteser Krankenhaus St Anna, Duisburg, Germany
    HNO 54:190-7. 2006
    ..The introduction of coblation tonsillectomy (CTE) may contribute to reduce the postoperative morbidity in terms of pain, delayed oral intake and bleeding...
  60. ncbi A comparison of aprotinin and lysine analogues in high-risk cardiac surgery
    Dean A Fergusson
    Ottawa Health Research Institute, Ottawa, Canada
    N Engl J Med 358:2319-31. 2008
    ..We sought to determine whether aprotinin was superior to either tranexamic acid or aminocaproic acid in decreasing massive postoperative bleeding and other clinically important consequences...
  61. ncbi A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulceration
    Y Yamaguchi
    The Third Department of Internal Medicine, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Aliment Pharmacol Ther 21:111-5. 2005
    ..However, uncertain whether an histamine2-receptor antagonist or proton-pump inhibitor is more effective...
  62. ncbi Effect of topical tranexamic acid in open heart surgery
    A Abul-Azm
    Department of Cardiothoracic Surgery, Cairo University, Kasr El Ainy Faculty of Medicine, Cairo, Egypt
    Eur J Anaesthesiol 23:380-4. 2006
    ..We have evaluated the effect of the topical use of tranexamic acid in the pericardial cavity on postoperative bleeding following open heart surgery...
  63. ncbi Aprotinin in cardiac surgery
    Victor A Ferraris
    N Engl J Med 354:1953-7; author reply 1953-7. 2006
  64. ncbi The role of histology and other risk factors for post-tonsillectomy haemorrhage
    A Schrock
    Department of Otolaryngology, Head and Neck Surgery, University of Bonn, Bonn, Germany
    Eur Arch Otorhinolaryngol 266:1983-7. 2009
    ..Because a multifactorial aetiology of post-tonsillectomy haemorrhage has to be assumed, large multicenter studies are necessary to evaluate the significance of different risk factors...
  65. ncbi The value of phase 4 clinical testing
    Gus J Vlahakes
    N Engl J Med 354:413-5. 2006
  66. doi Aprotinin and lysine analogues in high-risk cardiac surgery
    Robert J Porte
    N Engl J Med 359:1181; author reply 1181-2. 2008
  67. ncbi Aprotinin in cardiac surgery
    Jeremiah R Brown
    N Engl J Med 354:1953-7; author reply 1953-7. 2006
  68. ncbi Low-dose aspirin and clopidogrel: how to act in patients scheduled for day surgery
    Frederique Servin
    Department of Anaesthesia and Intensive Care, Bichat Hospital, Paris, France
    Curr Opin Anaesthesiol 20:531-4. 2007
    ..The purpose of this review is to examine the most recent findings and integrate them into the ambulatory surgery setting...
  69. ncbi Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysis
    Jeffrey S Berger
    Division of Cardiology, Duke University School of Medicine, Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 52:1693-701. 2008
    ..S. hospitals...
  70. ncbi Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism
    W Morawski
    First Cardiac Surgery Department, Medical University of Silesia, Katowice, Poland
    J Thorac Cardiovasc Surg 130:791-6. 2005
    ..We also aimed to assess the effects of aspirin pretreatment and to ascertain the value of platelet function studies as predictors of postoperative bleeding...
  71. ncbi Costs of excessive postoperative hemorrhage in cardiac surgery
    Michael C Christensen
    Global Development, Novo Nordisk A S, Bagsvaerd, Denmark
    J Thorac Cardiovasc Surg 138:687-93. 2009
    Excessive postoperative hemorrhage in cardiac surgery is a serious clinical complication placing substantial demands on hospital resources. This study quantifies the exact impact of postoperative hemorrhage on hospital costs in Germany.
  72. ncbi Effect of preoperative aspirin use in off-pump coronary artery bypass operations
    Arun K Srinivasan
    Department of Cardiothoracic Surgery, Liverpool, United Kingdom
    Ann Thorac Surg 76:41-5. 2003
    ..We aimed to determine the effects of continuing aspirin therapy preoperatively...
  73. ncbi Aprotinin and lysine analogues in high-risk cardiac surgery
    Paul S Myles
    N Engl J Med 359:1181; author reply 1181-2. 2008
  74. ncbi Risk factors for bleeding after endoscopic mucosal resection
    Masatsugu Shiba
    Department of Gastroenterology, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    World J Gastroenterol 11:7335-9. 2005
    ..To clarify the risk factors for bleeding after endoscopic mucosal resection (EMR)...
  75. ncbi Effects of recombinant factor VIIa in haemorrhagic complications of urological operations
    Grazyna Michalska-Krzanowska
    Department of Anaestahesiology and Intensive care Unit of the Clinical State Hospital No 2, Szczecin, Poland
    Acta Haematol 109:158-60. 2003
  76. ncbi Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleeding
    A Mayo
    Department of Surgery B, Sourasky Tel Aviv Medical Center, Tel Aviv, Israel
    Vox Sang 87:34-40. 2004
    ..A protocol for its use in acute, uncontrolled life-threatening bleeding, was devised and employed. A haematologist/transfusion specialist was assigned as a member of the team...
  77. ncbi Bloodless medicine: clinical care without allogeneic blood transfusion
    Lawrence T Goodnough
    Washington University School of Medicine, St Louis, Missouri, USA
    Transfusion 43:668-76. 2003
  78. doi Reduced levels of fibrin (antithrombin I) and antithrombin III underlie coagulopathy following complex cardiac surgery
    Roman M Sniecinski
    Blood Coagul Fibrinolysis 19:178-9. 2008
  79. ncbi Successful treatment with recombinant factor VIIa for intractable bleeding at pelvic surgery
    Jarosław Daniloś
    First Department of Gynecology, Medical University, Lublin, Poland
    Obstet Gynecol 101:1172-3. 2003
    ..Postoperative bleeding may be complicated by failure to identify the site of bleeding, multiple bleeding points, and persistent hemorrhage despite surgical intervention...
  80. ncbi Use of recombinant activated factor VII concentrate to control postoperative hemorrhage in complex cardiovascular surgery
    Lyndsey J Bowman
    Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Ann Thorac Surg 85:1669-76; discussion 1676-7. 2008
    Complex cardiovascular surgery often results in postoperative hemorrhage. Excessive blood product use may cause systemic thrombosis, end-organ dysfunction, and edema preventing chest closure...
  81. ncbi Management of delayed postoperative hemorrhage after pancreaticoduodenectomy: a meta-analysis
    Paolo Limongelli
    HPB Unit, Division of Surgery and Intensive Care, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London, England
    Arch Surg 143:1001-7; discussion 1007. 2008
    To determine whether interventional radiology (IR) or laparotomy (LAP) is the best management of delayed postoperative hemorrhage (DPH) after pancreaticoduodenectomy...
  82. ncbi A case of hepatic artery embolization and partial arterialization of the portal vein for intraperitoneal, hemorrhage after a pancreaticoduodenectomy
    Kenichi Teramoto
    Department of Surgery, Division of Hepato Biliary Pancreatic Surgery, Tokyo Medical and Dental University, Yushima 1 5 45, Bunkyo ku, Tokyo, Japan
    Hepatogastroenterology 50:1217-9. 2003
    ..Whether the partial portal vein arterialization was effective is unclear, but partial portal vein arterialization should be considered as an option in cases of total hepatic artery occlusion with impairment of portal blood flow...
  83. ncbi The effect of preoperative clopidogrel on bleeding after coronary artery bypass surgery
    Wade Kang
    Department of Surgery, St Luke s Hospital and Health Network, Bethlehem, Pennsylvania 18015, USA
    J Surg Educ 64:88-92. 2007
    ..The purpose of this study was to analyze the effect of preoperative clopidogrel exposure on bleeding complications, blood transfusions requirements, and reoperations in patients undergoing coronary artery bypass grafting (CABG)...
  84. ncbi Postoperative bypass bleeding: a bypass-associated dilutional (BAD) coagulopathy?
    Brian S Bull
    School of Medicine, Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA 92350, USA
    Blood Cells Mol Dis 43:256-9. 2009
    ..The presence of un-neutralized protamine combined with critically lowered clotting factors leads to marked coagulopathy...
  85. ncbi Recombinant activated factor VII in cardiac surgery: a meta-analysis
    Alberto Zangrillo
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia
    J Cardiothorac Vasc Anesth 23:34-40. 2009
    ..Few trials have investigated rFVIIa and each individually lacked power to detect a beneficial effect on transfusion of blood products or thromboembolic side effects...
  86. pmc Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery: a review and meta-analysis of published data
    Christian von Heymann
    Department of Anesthesiology and Intensive Care Medicine, Charite University Medicine Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Augustenburger Platz 1, 13353 Berlin, Germany
    Crit Care 12:R14. 2008
    ..The purpose of this study was to determine the role of recombinant activated factor VII (rFVIIa) in abdominal, vascular, and urological surgery...
  87. ncbi Recombinant activated factor vii to control massive post operative bleeding after septic aortobifemoral grafting
    M Raux
    Eur J Anaesthesiol 22:805-7. 2005
  88. pmc The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis
    David Henry
    School of Medicine and Public Health, University of Newcastle, Australia
    CMAJ 180:183-93. 2009
    ..Because of recent concerns about the safety of aprotinin, we updated our 2007 Cochrane review that compared the relative benefits and risks of aprotinin and the lysine analogues tranexamic acid and epsilon aminocaproic acid...
  89. ncbi Delayed massive arterial hemorrhage after pancreaticoduodenectomy for cancer. Management of a life-threatening complication
    Roberto Santoro
    Department of Oncological Surgery, Regina Elena Cancer Institute of Rome, Italy
    Hepatogastroenterology 50:2199-204. 2003
    ..The purpose of this study was to define diagnostic and treatment methodologies to maximize survival...
  90. ncbi Albumin versus hydroxyethyl starch in cardiopulmonary bypass surgery: a meta-analysis of postoperative bleeding
    M M Wilkes
    Hygeia Associates, Grass Valley, California 95949, USA
    Ann Thorac Surg 72:527-33; discussion 534. 2001
    ..This meta-analysis tested the hypothesis that cumulative blood loss during the first 24 hours after cardiopulmonary bypass is lower in patients exposed to albumin than hydroxyethyl starch (HES)...
  91. ncbi Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study
    Martin Karlsson
    Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
    Thromb Haemost 102:137-44. 2009
    ..Larger studies are necessary to ensure safety and confirm efficacy of prophylactic fibrinogen treatment in cardiac surgery...
  92. ncbi Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery
    Ravi Gill
    Cardiac Anaesthesia and Intensive Care Medicine, Southampton University Hospitals, Southampton, UK
    Circulation 120:21-7. 2009
    ..Our objective was to investigate the safety and possible benefits of rFVIIa in patients who bleed after cardiac surgery...
  93. ncbi Low-dose recombinant factor VIIa in the management of uncontrolled postoperative hemorrhage in cardiac surgery patients
    Ewoudt M W van de Garde
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    J Cardiothorac Vasc Anesth 20:573-5. 2006
  94. ncbi Management of early hemorrhage from pancreatic anastomoses after pancreaticoduodenectomy
    Moritz N Wente
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, DE 69120 Heidelberg, Germany
    Dig Surg 23:203-8. 2006
    ..The leading cause of emergency reexploration is early postoperative hemorrhage due to technical failure of hemostasis...
  95. ncbi Novel approach to bleeding in patients undergoing cardiac surgery with liver dysfunction
    R G Stuklis
    Department of Cardiothoracic Surgery and Haematology, Southampton General Hospital, Southampton, UK
    Eur J Cardiothorac Surg 19:219-20. 2001
    ..We describe two patients with significant liver dysfunction (Child--Pugh class B) who underwent cardiac surgery at our institution facilitated by the use of a prothrombin complex concentrate for the management of postoperative bleeding...
  96. ncbi Delayed re-exploration for bleeding after coronary artery bypass surgery results in adverse outcomes
    Cliff K Choong
    Papworth Hospital NHS Trust, Cambridge, United Kingdom
    Eur J Cardiothorac Surg 31:834-8. 2007
    ..We aimed to identify the impact of re-exploration for bleeding after coronary artery bypass grafting (CABG) and the effect of time delay, re-exploration within 12h (<12h) versus 12h or later (>or=12h)...
  97. ncbi Endovascular treatment of hemorrhage after tonsillectomy in children
    M J Opatowsky
    Department of Radiological Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    AJNR Am J Neuroradiol 22:713-6. 2001
    ..We report two cases of hemorrhage after tonsillectomy and/or adenoidectomy and describe the endovascular management of this complication in children...
  98. ncbi Early postoperative hemorrhage after open and laparoscopic roux-en-y gastric bypass
    Charles Bakhos
    Department of Surgery, Hospital of Saint Raphael, MOB 315, 1450 Chapel Street, New Haven, CT 06511, USA
    Obes Surg 19:153-7. 2009
    Early postoperative hemorrhage is an infrequent complication of both laparoscopic and open Roux-en-Y gastric bypass (RYGBP)...
  99. ncbi Successful treatment of severe intra-abdominal bleeding associated with disseminated intravascular coagulation using recombinant activated factor VII
    F Moscardo
    Department of Haematology, Hospital Universitario La Fe, Valencia, Spain
    Br J Haematol 114:174-6. 2001
    ..No side-effects related to rFVIIa were noted. This case suggests a potential role for rFVIIa in the treatment of severe and refractory bleeding associated with DIC...
  100. ncbi Correlation of perioperative platelet function and coagulation tests with bleeding after cardiopulmonary bypass surgery
    Roger C Carroll
    Department of Anesthesiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee 37920, USA
    J Lab Clin Med 147:197-204. 2006
    ..In three cases without negative surgery parameters, coagulation dysfunction was observed. The remaining five cases did not give a clear indication of which parameters were primarily responsible for the bleeding...
  101. ncbi Management of pelvic hemorrhage
    R S Tomacruz
    Department of Gynecology and Obstetrics The Johns Hopkins Hospital and Medical Institutions, Baltimore, Maryland 21287, USA
    Surg Clin North Am 81:925-48. 2001
    ....

Research Grants21

  1. Stroke Hospitalization in the Elderly with Medicare FFS
    Judith Lichtman; Fiscal Year: 2009
    ..These results will help inform decisions about the allocation of adequate resources, and more importantly, help identify opportunities to improve care and prevention of elderly stroke patients. ..
  2. Effect of lipid modification on peripheral arterial disease (PAD)
    Christie Ballantyne; Fiscal Year: 2007
    ..Finally, these studies will advance our understanding of the molecular mechanisms of inflammation and thrombosis associated with aggressive lipid modification. ..
  3. OU Developmental Center for Injury Prevention Research
    Gary Raskob; Fiscal Year: 2005
    ..abstract_text> ..
  4. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..
  5. Hospital Integration and Medicare Reimbursement Policy
    Daniel Kessler; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  6. ICOS-B7h in Islet Transplant Rejection and Autoimmunity
    Andrew Shapiro; Fiscal Year: 2004
    ....
  7. Impact of Aging on Stroke Care: A National Perspective
    Judith Lichtman; Fiscal Year: 2004
    ..We hypothesize that variations in care exist by age. Moreover, these differences in care will not be explained by differences clinical features or co-morbid conditions associated with aging. ..
  8. PHARMACOGENETICS IN SURGICAL CRITICAL CARE
    Bradley Freeman; Fiscal Year: 2004
    ..The environment for this project is Washington University School of Medicine, an institution with access to a large clinical volume and established expertise in genomic research. ..
  9. OU Human Research Protection Program, Year 2
    Gary Raskob; Fiscal Year: 2003
    ..The University of Oklahoma is committed to maintaining these initiatives after the term of this award. ..
  10. Reducing Sedative Exposure in Ventilated ICU Patients
    Linda Chlan; Fiscal Year: 2009
    ..abstract_text> ..
  11. Insulin Resistance and Adenomas of the Colorectum
    Theodore Levin; Fiscal Year: 2003
    ..abstract_text> ..
  12. TRIAL OF ANTI-TNF ALPHA IN ISLET TRANSPLANTATION
    Andrew Shapiro; Fiscal Year: 2002
    ....
  13. Improving use of peri-operative beta-blockers with a multidimentional QI program
    Andrew Auerbach; Fiscal Year: 2009
    ..The impact of this set of tools will be substantial as groups such as the NSQIP, SCIP, National Quality Forum, and Leapfrog Group continue to endorse PBB as a key strategy to reduce surgical morbidity and mortality. ..
  14. Angiogenesis and Cardiac Growth as Heart Failure Therapy
    Y Woo; Fiscal Year: 2008
    ..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
  15. Endothelial progenitor cells and surgical outcomes
    Andrew Auerbach; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Nanostenting Hydrogels for Sinus Surgery
    RICHARD ORLANDI; Fiscal Year: 2004
    ..The results of these Phase I studies will determine the feasibility and the optimal chemical properties of a nanostenting HA gel for human trials. ..
  17. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  18. GLOBAL ANALYSIS OF TECHNOLOGICAL CHANGE IN HEALTH CARE
    Daniel Kessler; Fiscal Year: 2002
    ..abstract_text> ..
  19. SLC2A9, A Candidate ER GLUT in Normal and Cancer Cells
    Jeffrey Moley; Fiscal Year: 2002
    ..Identification of SLC2A9 as the endoplasmic reticulum glucose transporter will improve understanding of GSDs, and of glucose metabolism in benign and malignant tissues. ..