hematoma

Summary

Summary: An extravasation of blood localized in an organ, space, or tissue.

Top Publications

  1. ncbi The clinical spectrum of retroperitoneal hematoma in anticoagulated patients
    Camilo González
    Intensive Care Unit, Hospital U M Valdecilla, University of Cantabria, Santander, Spain
    Medicine (Baltimore) 82:257-62. 2003
  2. ncbi Rectus sheath hematoma: review of 126 cases at a single institution
    W Brett Cherry
    Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 85:105-10. 2006
  3. doi Hematoma resolution as a therapeutic target: the role of microglia/macrophages
    Xiurong Zhao
    Professor of Neurology, Director of Stroke Research, Department of Neurology, University of Texas Houston Medical School, Houston, TX 77030, USA
    Stroke 40:S92-4. 2009
  4. ncbi Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages
    Xiurong Zhao
    Stroke Program, Department of Neurology, University of Texas Houston Medical School, Houston, TX 77030, USA
    Ann Neurol 61:352-62. 2007
  5. doi Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
    Stephan A Mayer
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, USA
    N Engl J Med 358:2127-37. 2008
  6. pmc Hematoma expansion following acute intracerebral hemorrhage
    H Bart Brouwers
    Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Cerebrovasc Dis 35:195-201. 2013
  7. ncbi FDG-PET imaging for chronic expanding hematoma in pelvis with massive bone destruction
    Kenichiro Hamada
    Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Skeletal Radiol 34:807-11. 2005
  8. doi Circulating MicroRNAs as potential risk biomarkers for hematoma enlargement after intracerebral hemorrhage
    Hong Wei Zheng
    Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, China
    CNS Neurosci Ther 18:1003-11. 2012
  9. doi The effect of brain hematoma location on volumetric inductive phase shift spectroscopy of the brain with circular and magnetron sensor coils: a numerical simulation study
    R Rojas
    Universidad del Ejército y FAM EMGS Laboratorio Multidisciplinario de Investigación, DF, Mexico
    Physiol Meas 29:S255-66. 2008
  10. ncbi Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat
    Ludmila Belayev
    Cerebral Vascular Disease Research Center, Department of Neurology D4 5, University of Miami School of Medicine, PO Box 016960, Miami, FL 33101, USA
    Stroke 36:326-31. 2005

Detail Information

Publications286 found, 100 shown here

  1. ncbi The clinical spectrum of retroperitoneal hematoma in anticoagulated patients
    Camilo González
    Intensive Care Unit, Hospital U M Valdecilla, University of Cantabria, Santander, Spain
    Medicine (Baltimore) 82:257-62. 2003
    ..We reviewed the cases diagnosed at our institution and reported in the literature to delineate the clinical manifestations and course of this process...
  2. ncbi Rectus sheath hematoma: review of 126 cases at a single institution
    W Brett Cherry
    Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 85:105-10. 2006
    Rectus sheath hematoma (RSH) is an uncommon condition characterized by abdominal pain and an abdominal wall mass...
  3. doi Hematoma resolution as a therapeutic target: the role of microglia/macrophages
    Xiurong Zhao
    Professor of Neurology, Director of Stroke Research, Department of Neurology, University of Texas Houston Medical School, Houston, TX 77030, USA
    Stroke 40:S92-4. 2009
    ..Within hours to days after ICH, extravasated erythrocytes in the hematoma undergo lysis, releasing cytotoxic hemoglobin, heme, and iron, thereby initiating secondary processes, which ..
  4. ncbi Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages
    Xiurong Zhao
    Stroke Program, Department of Neurology, University of Texas Houston Medical School, Houston, TX 77030, USA
    Ann Neurol 61:352-62. 2007
    Phagocytosis is necessary to eliminate the hematoma after intracerebral hemorrhage (ICH); however, release of proinflammatory mediators and free radicals during phagocyte activation is toxic to neighboring cells, leading to secondary ..
  5. doi Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
    Stephan A Mayer
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, USA
    N Engl J Med 358:2127-37. 2008
    ..We performed this phase 3 trial to confirm a previous study in which recombinant activated factor VII (rFVIIa) reduced growth of the hematoma and improved survival and functional outcomes.
  6. pmc Hematoma expansion following acute intracerebral hemorrhage
    H Bart Brouwers
    Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Cerebrovasc Dis 35:195-201. 2013
    ..Location and baseline hematoma volume are strong predictors of mortality, but are nonmodifiable by the time of diagnosis...
  7. ncbi FDG-PET imaging for chronic expanding hematoma in pelvis with massive bone destruction
    Kenichiro Hamada
    Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Skeletal Radiol 34:807-11. 2005
    Chronic expanding hematoma is a rare presentation of a hematoma characterized by a persistent increase in size for more than a month after the initial hemorrhage...
  8. doi Circulating MicroRNAs as potential risk biomarkers for hematoma enlargement after intracerebral hemorrhage
    Hong Wei Zheng
    Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, China
    CNS Neurosci Ther 18:1003-11. 2012
    ..The aim of this study was to investigate whether miRNAs can be used as biomarkers to predict secondary hematoma enlargement (HE) in patients with ICH.
  9. doi The effect of brain hematoma location on volumetric inductive phase shift spectroscopy of the brain with circular and magnetron sensor coils: a numerical simulation study
    R Rojas
    Universidad del Ejército y FAM EMGS Laboratorio Multidisciplinario de Investigación, DF, Mexico
    Physiol Meas 29:S255-66. 2008
    This numerical simulation study addressed the effects of the location of a discrete brain hematoma on the volumetric inductive phase shift of the brain measured with an induction circular sensor coil and an induction magnetron sensor coil...
  10. ncbi Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat
    Ludmila Belayev
    Cerebral Vascular Disease Research Center, Department of Neurology D4 5, University of Miami School of Medicine, PO Box 016960, Miami, FL 33101, USA
    Stroke 36:326-31. 2005
    ....
  11. doi Density and shape as CT predictors of intracerebral hemorrhage growth
    Christen D Barras
    Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Stroke 40:1325-31. 2009
    Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would ..
  12. pmc Human early fracture hematoma is characterized by inflammation and hypoxia
    Paula Kolar
    Department of Rheumatology and Clinical Immunology, Charite University Hospital, Chariteplatz 1, 10117 Berlin, Germany
    Clin Orthop Relat Res 469:3118-26. 2011
    An effective immune system, especially during the inflammatory phase, putatively influences the quality and likelihood of bone healing. If and how this is reflected within the initial fracture hematoma is unclear.
  13. ncbi Multivariate analysis of predictors of hematoma enlargement in spontaneous intracerebral hemorrhage
    Y Fujii
    Department of Neurosurgery, Niigata University, Japan
    Stroke 29:1160-6. 1998
    We conducted this study to determine, through use of multivariate analyses, the independent predictors of hematoma enlargement occurring after hospital admission in patients with spontaneous intracerebral hemorrhage (i.c.h.).
  14. doi Intracorneal hematoma after canaloplasty in glaucoma
    Maurizio Gismondi
    Department of Ophthalmology, Azienda Ospedaliero Universitaria Santa Maria della Misericordia, Udine, Italy
    Cornea 30:718-9. 2011
    To report a case of an intracorneal hematoma after canaloplasty.
  15. doi Intramural hematoma of the pulmonary artery and hemopneumomediastinum after endobronchial ultrasound-guided transbronchial needle aspiration
    Maribel Botana-Rial
    Bronchopleural Techniques Unit, Pulmonology Service, Respiratory and Infectious Disease Research Group, Biomedical Research Institute, Complexo Hospitalario Universitario de Vigo, Vigo, Spain
    Respiration 83:353-6. 2012
    ..We describe the first reported case of pulmonary artery intramural hematoma after EBUS-TBNA puncture of this artery. The complication was visualized by ultrasound and resolved spontaneously.
  16. ncbi Postoperative hematomas after thyroid surgery. Incidence and risk factors in our experience
    Pietro Giorgio Calò
    Dipartimento di Chirurgia e Scienze Odontostomatologiche, Universita degli Studi di Cagliari, Italy
    Ann Ital Chir 81:343-7. 2010
    ..The aim of our study was to evaluate the incidence and timing of postoperative bleeding and to identify the potential aetiological factors of cervical hematomas complicating thyroid surgery...
  17. doi Minimally invasive procedures for evacuation of intracerebral hemorrhage reduces perihematomal glutamate content, blood-brain barrier permeability and brain edema in rabbits
    Guofeng Wu
    Department of Emergency, Affiliated Hospital, Guiyang Medical College, Guiyang City, Guizhou Province, China
    Neurocrit Care 14:118-26. 2011
    To observe the effects of the minimally invasive removal of an intracerebral hematoma on the glutamate concentration, blood-brain barrier (BBB) permeability and brain water content in the brain tissue surrounding the hematoma and to ..
  18. pmc Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma
    Qun Su
    Intensive Care Unit, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Yonsei Med J 51:793-6. 2010
    ..08. Head computed topography revealed intracerebral hematoma in the left temporoparietal region. Both warfarin therapy and the herbal product were withdrawn...
  19. ncbi Spontaneous intramural small-bowel hematoma: imaging findings and outcome
    Maher A Abbas
    Department of Surgery, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
    AJR Am J Roentgenol 179:1389-94. 2002
    Our aim was to review the imaging findings and outcomes of patients with nontraumatic spontaneous intramural small-bowel hematoma.
  20. ncbi A theoretical study on magnetic induction frequency dependence of phase shift in oedema and haematoma
    César A González
    Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA
    Physiol Meas 27:829-38. 2006
    ..The results indicate that bulk induction measurement of the phase shift has the potential for becoming a simple means for non-contact detection of formation of oedema and haematoma in brain, lung and muscle tissues...
  21. ncbi Frame-based and frameless stereotactic hematoma puncture and subsequent fibrinolytic therapy for the treatment of spontaneous intracerebral hemorrhage
    Ruth Thiex
    Department of Neurosurgery, Aachen University, Pauwelsstr 30, 52057, Aachen, Germany
    J Neurol 251:1443-50. 2004
    ..Comparison of two minimally invasive procedures for the treatment of intracerebral hemorrhage and subsequent lysis with regard to technical implications and clinical outcome of the patients...
  22. ncbi Endoscopic evacuation of putaminal hemorrhage: how to improve the efficiency of hematoma evacuation
    Po Chun Hsieh
    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan, Republic of China
    Surg Neurol 64:147-53; discussion 153. 2005
    ..A simplified method to determine the precise location for burr hole placement is also reported...
  23. ncbi Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study
    Candice Delcourt
    The George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Australia
    Neurology 79:314-9. 2012
    Uncertainty exists over the size of potential beneficial effects of medical treatments targeting hematoma growth in intracerebral hemorrhage (ICH)...
  24. ncbi Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage
    J J Flibotte
    Stroke Service and Neurology Clinical Trials Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Neurology 63:1059-64. 2004
    ..Warfarin increases mortality of intracerebral hemorrhage (ICH). The authors investigated whether this effect reflects increased baseline ICH volume at presentation or increased ICH expansion...
  25. ncbi The long-term effect of recombinant tissue-plasminogen-activator (rt-PA) on edema formation in a large-animal model of intracerebral hemorrhage
    Ruth Thiex
    Department of Neurosurgery, Aachen University, Pauwelsstr 30, 52057 Aachen, Germany
    Neurol Res 25:254-62. 2003
    b>Hematoma puncture, fibrinolysis, and aspiration of the liquefied clot is a promising new treatment strategy for large intracerebral hemorrhages (ICH)...
  26. doi Reperfusion-associated hemorrhagic transformation in SHR rats: evidence of symptomatic parenchymal hematoma
    Erica C Henning
    Section on Stroke Diagnostics and Therapeutics, Stroke Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
    Stroke 39:3405-10. 2008
    ..In this study, we used multimodal magnetic resonance imaging to investigate the incidence and severity of reperfusion-based HT in spontaneously hypertensive rats after ischemia/reperfusion...
  27. ncbi Femoral nerve palsy secondary to traumatic pseudoaneurysm and iliacus hematoma
    Adam S Rochman
    Department of Neurosurgery, The Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, Florida, USA
    J Neurosurg 102:382-5. 2005
    ..a case of traumatic femoral nerve palsy caused by a pseudoaneurysm of the iliolumbar artery and a iliacus muscle hematoma. This case report details not only the classic history and physical findings seen in patients such as this one, ..
  28. ncbi Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat
    Timothy D Ardizzone
    Department of Neurology, University of Cincinnati College of Medicine, Ohio, USA
    Stroke 35:2587-91. 2004
    ..To develop successful treatments, we must learn more about the effects of hemorrhage on brain tissue. In this study, we investigated the acute metabolic effects of intrastriatal hemorrhage in rat brain...
  29. ncbi Hematoma-directed ultrasound-guided (HUG) breast lumpectomy
    Margaret Thompson
    Division of Breast Surgical Oncology, Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Ann Surg Oncol 14:148-56. 2007
    ....
  30. pmc Defining hematoma expansion in intracerebral hemorrhage: relationship with patient outcomes
    D Dowlatshahi
    University of Ottawa, Ottawa Hospital Civic Campus, Ottawa, Ontario, Canada
    Neurology 76:1238-44. 2011
    b>Hematoma expansion (HE) is a surrogate marker in intracerebral hemorrhage (ICH) trials...
  31. ncbi Intracorneal hematoma with descemet membrane detachment after viscocanalostomy
    Hiroko Fujimoto
    Nagata Eye Clinic, Nara, Japan
    Am J Ophthalmol 137:195-6. 2004
    To describe a case of intracorneal hematoma with Descemet membrane detachment after viscocanalostomy.
  32. ncbi Retroperitoneal hematoma associated with femoral neuropathy: a complication under antiplatelets therapy
    A Nakao
    Department of Surgery I, Okayama University Medical School, Japan
    Acta Med Okayama 55:363-6. 2001
    We report a case of retroperitoneal hematoma presenting as femoral nerve pulsy on antiplatelet therapy...
  33. pmc Comparison of hematoma shape and volume estimates in warfarin versus non-warfarin-related intracerebral hemorrhage
    Kevin N Sheth
    Division of Neurology, University of Maryland Medical Center, Baltimore, MD, USA
    Neurocrit Care 12:30-4. 2010
    b>Hematoma volume is a major determinant of outcome in patients with intracerebral hemorrhage (ICH)...
  34. pmc Experimental model of warfarin-associated intracerebral hemorrhage
    Christian Foerch
    Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, Masschusetts 02129, USA
    Stroke 39:3397-404. 2008
    ..This study describes the development of a mouse model of W-ICH in which hematoma growth and outcomes can be correlated with anticoagulation parameters.
  35. pmc Hematoma-directed ultrasound-guided breast biopsy
    L F Smith
    Departments of Surgery, Radiology, and Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Ann Surg 233:669-75. 2001
    ..A hematoma consisting of 2 to 5 mL of the patient's own blood was injected into the breast to target the nonpalpable lesion...
  36. ncbi Spontaneous duodenal hematoma
    Mustafa Secil
    Department of Radiology, Dokuz Eylul University Medical School Hospital, Izmir, Turkey
    J Emerg Med 27:291-3. 2004
  37. pmc Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage
    Arne Lauer
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Circulation 124:1654-62. 2011
    ..Whereas warfarin pretreatment is associated with greater hematoma expansion after intracerebral hemorrhage (ICH), it remains unclear what effect direct thrombin inhibitors would ..
  38. doi Femoral nerve palsy associated with iliacus hematoma following pseudoaneurysm after revision hip arthroplasty
    Yoshihide Nakamura
    Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
    J Arthroplasty 23:1240.e1-4. 2008
    Iliacus hematoma associated with femoral nerve palsy is a very rare but considerable complication of hip arthroplasty. A 76-year-old woman had femoral nerve palsy 6 months after revision hip arthroplasty using a reinforcement plate...
  39. ncbi Non-neoplastic conditions presenting as soft-tissue tumours
    N Crundwell
    Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    Clin Radiol 62:18-27. 2007
    ..The most common diagnoses were myositis ossificans, ganglion cyst, abscess/infection, bursitis and synovitis. The imaging features of other rarer conditions will also be discussed...
  40. doi Hematoma size as major modulator of the cellular immune system after experimental intracerebral hemorrhage
    Sergio Illanes
    Department of Neurology, University Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neurosci Lett 490:170-4. 2011
    ..We examined the effects of different hematoma volumes on immune cell subpopulations in experimental murine ICH...
  41. ncbi Spontaneous retroclival hematoma presenting as a thunderclap headache. Case report
    W I Schievink
    Maxine Dunitz Neurosurgical Institute and Imaging Medical Group, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Neurosurg 95:522-4. 2001
    ..The authors describe a patient with this type of headache who was found to have a spontaneous retroclival hematoma. A 49-year-old woman experienced an instantaneous excruciating headache...
  42. ncbi Enoxaparin-associated severe retroperitoneal bleeding and abdominal compartment syndrome: a report of two cases
    A Dabney
    Division of Nephrology, Department of Internal Medicine, Saint Louis University School of Medicine, 3635 Vista Avenue, St. Louis, MO 63110, USA
    Intensive Care Med 27:1954-7. 2001
    ..PATIENTS: Two adult patients receiving enoxaparin developed retroperitoneal hematoma and abdominal compartment syndrome...
  43. ncbi Progression of mass effect after intracerebral hemorrhage
    A R Zazulia
    Departments of Neurology and Neurological Surgery, Lillian Strauss Institute for Neuroscience of the Jewish Hospital of St Louis, MO, USA
    Stroke 30:1167-73. 1999
    ..Our goal was to determine the time course and cause for progression of mass effect after ICH...
  44. ncbi Intracerebral hemorrhage models in rat: comparing collagenase to blood infusion
    Crystal L MacLellan
    Department of Psychology and Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada
    J Cereb Blood Flow Metab 28:516-25. 2008
    ..An ICH was created by infusing blood or bacterial collagenase into the rats' striatum. We matched initial hematoma volume in each model (Experiment 1) and assessed the time course of bleeding (Experiment 2)...
  45. ncbi Blood pressure management in acute intracerebral hemorrhage: relationship between elevated blood pressure and hematoma enlargement
    Kazuhiro Ohwaki
    Department of Hygiene and Public Health, Teikyo University School of Medicine, 2 11 1 Kaga Itabashi, Tokyo 173 8605, Japan
    Stroke 35:1364-7. 2004
    The association between elevated blood pressure (BP) and hematoma enlargement in acute intracerebral hemorrhage (ICH) has not been clarified...
  46. pmc Significant abdominal wall hematoma from an umbilical port insertion
    I Marcovici
    Department of Obstetrics and Gynecology, University of Michigan Medical Center, University of Michigan, Ann Arbor 48109 0276, USA
    JSLS 5:293-5. 2001
    Laparoscopists consider the umbilical and ventral midline area to be "vascular safe." On occasion, however, the insertion of the first trocar at the umbilical port may result in severe abdominal wall hematoma.
  47. ncbi Chronological changes of perihematomal edema of human intracerebral hematoma
    M Inaji
    Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan
    Acta Neurochir Suppl 86:445-8. 2003
    ..of intracerebral hemorrhage (ICH), which includes ischemic brain damage and edema formation around a hematoma. The purpose of the current study is to investigate chronological changes of perihematomal edema in patients with ..
  48. pmc Chronic expanding hematoma of the thorax
    Yong Soo Kwon
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, Korea
    Yonsei Med J 48:337-40. 2007
    We report the first case in Korea of a chronic expanding hematoma, which presented as a huge mass in the pleural cavity...
  49. doi Extrathoracic protrusion of a chronic expanding hematoma in the chest mimicking a soft tissue tumor
    Makoto Takahama
    Department of General Thoracic Surgery, Osaka City General Hospital, 2 13 22 Miyakojima Hondori, Miyakojima ku, Osaka, 534 0021, Japan
    Gen Thorac Cardiovasc Surg 58:202-4. 2010
    We report an uncommon clinical case of extrathoracic protrusion of a chronic expanding hematoma in the chest, mimicking a soft tissue sarcoma...
  50. ncbi Arterial puncture closing devices compared with standard manual compression after cardiac catheterization: systematic review and meta-analysis
    Maria Koreny
    Department of Emergency Medicine, University of Vienna, Vienna General Hospital, Vienna, Austria
    JAMA 291:350-7. 2004
    ..Arterial puncture closing devices (APCDs) were developed to replace standard compression at the puncture site and to shorten bed rest following percutaneous coronary intervention...
  51. ncbi Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial
    A David Mendelow
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK
    Lancet 365:387-97. 2005
    ..We undertook a prospective randomised trial to compare early surgery with initial conservative treatment for patients with intracerebral haemorrhage...
  52. ncbi Molecular signatures of vascular injury are associated with early growth of intracerebral hemorrhage
    Yolanda Silva
    Department of Neurology, Hospital Doctor Josep Trueta, Girona, Spain
    Stroke 36:86-91. 2005
    ..To investigate whether molecular markers of inflammation and endothelial injury are associated with early growth of intracerebral hemorrhage (ICH)...
  53. pmc Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery
    Antonio Rios Zambudio
    Department of General Surgery and Digestive Apparatus I, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
    Ann Surg 240:18-25. 2004
    ....
  54. ncbi Rectus sheath hematoma: a series of unfortunate events
    Andreas Luhmann
    Royal Glamorgan Hospital, Ynys Maerdy, Llantrisant, CF72 8XR, UK
    World J Surg 30:2050-5. 2006
    Rectus sheath hematoma is rare. It can present to physicians in many specialties, but invariably the surgeon is contacted regarding management...
  55. ncbi Lidocaine-induced altered mental status and seizure after hematoma block
    Erik Dorf
    Department of Orthopedic Surgery, University of Virginia, Charlottesville, Virginia, USA
    J Emerg Med 31:251-3. 2006
    b>Hematoma blocks with lidocaine are routinely utilized in the Emergency Department to allow reduction of Colles' fractures. Lidocaine toxicity is a potential complication of this procedure...
  56. ncbi Percutaneous arterial embolization in the management of rectus sheath hematoma
    Jordi Rimola
    Department of Radiology, UDIAT CD, Corporacio Sanitaria Parc Tauli, Sabadell, Barcelona, Spain
    AJR Am J Roentgenol 188:W497-502. 2007
    OBJECTIVE: Spontaneous rectus sheath hematoma can become clinically relevant and necessitate hemostatic intervention...
  57. ncbi Extensive retroperitoneal hematoma without neurologic deficit in two patients who underwent lumbar plexus block and were later anticoagulated
    Robert S Weller
    Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Anesthesiology 98:581-5. 2003
  58. ncbi Spontaneous parapharyngeal haematoma caused by a leaking vertebral artery pseudoaneurysm
    Khaled Badran
    Department of Otolaryngology and Skull Base Surgery, Addenbrooke s Hospital, Cambridge, UK
    Eur Arch Otorhinolaryngol 265:251-4. 2008
    ..This is the first reported case of a parapharyngeal haematoma originating from a vertebral artery pseudoaneurysm where imaging demonstrated a causal link...
  59. doi Clinicopathological study on chronic encapsulated expanding hematoma associated with incompletely obliterated AVM after stereotactic radiosurgery
    Akira Nakamizo
    Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Acta Neurochir (Wien) 153:883-93. 2011
    Chronic encapsulated expanding hematoma is a rare, but highly morbid, severe complication after stereotactic radiosurgery for intracerebral arteriovenous malformations (AVMs)...
  60. doi Incidence and circumstances of cervical hematoma complicating thyroidectomy and its relationship to postoperative vomiting
    Marco Bononi
    Department of Surgery Pietro Valdoni, University of Rome Sapienza, Rome, Italy
    Head Neck 32:1173-7. 2010
    Cervical hematoma is hardly a predictable complication of thyroid surgery. Postoperative vomiting has been reported as a likely risk factor.
  61. doi The pathophysiological time window study of performing minimally invasive procedures for the intracerebral hematoma evacuation in rabbit
    Guofeng Wu
    Department of Neurology, Affiliated Hospital, Guiyang Medical College, No 28, Guiyijie Road, Liuguangmen, Guiyang City, Guizhou Province 550004, PR China
    Brain Res 1465:57-65. 2012
    ..to observe the pathophysiological time window of performing minimally invasive procedures for the intracerebral hematoma evacuation...
  62. ncbi Acute aortic intramural hematoma: an analysis from the International Registry of Acute Aortic Dissection
    Kevin M Harris
    Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
    Circulation 126:S91-6. 2012
    Acute aortic intramural hematoma (IMH) is an important subgroup of aortic dissection, and controversy surrounds appropriate management.
  63. ncbi [A case of chronic expanding hematoma in retroperitoneal space]
    Gou Kaneko
    The Department of Urology, Kawasaki Municipal Hospital
    Hinyokika Kiyo 55:603-6. 2009
    ..The mass was suspected to be chronic expanding hematoma or neurogenic tumor of renal capsule origin...
  64. ncbi [A case of intrarenal hematoma: role of ultrasonography in the early diagnosis of a possible complication of anticoagulant therapy]
    Mauro Dugo
    Nefrologia, Dialisi e Trapianti Renali, Ospedale Ca Foncello, Treviso, Italy
    G Ital Nefrol 29:616-20. 2012
    ..We report a case of intrarenal hematoma arising in a uremic patient treated with warfarin...
  65. doi Imaging and clinical prognostic indicators for early hematoma enlargement after spontaneous intracerebral hemorrhage
    Nan Ji
    Department of Neurosurgery, Tiantan Hospital, Capital Medical University, Beijing, China
    Neurol Res 31:362-6. 2009
    To analyse the imaging and clinical prognostic indicators for early hematoma enlargement after spontaneous intracerebral hemorrhage (ICH).
  66. pmc Hematoma volume measurement in gradient echo MRI using quantitative susceptibility mapping
    Shuo Wang
    Department of Radiology, Weill Medical College of Cornell University, New York, NY 10022, USA
    Stroke 44:2315-7. 2013
    ..We hypothesize that hematoma volume measurement on QSM is independent of imaging parameters, eliminating its echo time dependence on gradient ..
  67. doi Combination of T2*W and FLAIR abnormalities for the prediction of parenchymal hematoma following thrombolytic therapy in 100 stroke patients
    Jens Fiehler
    Department of Neuroradiology, University Medical Care Hamburg Eppendorf, Hamburg, Germany
    J Neuroimaging 19:311-6. 2009
    The objective of our study was to determine whether the combination of hypointense spots ("cerebral microbleeds," CMBs) with a leukoaraiosis is associated with the risk of parenchymal hematoma (PH) after thrombolytic therapy.
  68. pmc Age determination of vessel wall hematoma in spontaneous cervical artery dissection: a multi-sequence 3T cardiovascular magnetic resonance study
    Maximilian Habs
    Dept, of Clinical Radiology, University of Munich, Grosshadern Campus, Munich, Germany
    J Cardiovasc Magn Reson 13:76. 2011
    ..proposed classifications for carotid plaque and cerebral parenchymal hemorrhages are used to estimate the age of hematoma according to its signal intensities on T1w and T2w MR images...
  69. doi Chronic expanding hematoma of the thigh
    Kohei Negoro
    Department of Orthopaedics and Rehabilitation Medicine, Fukui University, Faculty of Medical Sciences, Matsuoka Shimoaizuki 23 3, Eiheiji, Fukui 910 1193, Japan
    Joint Bone Spine 79:192-4. 2012
    ..In some instances, for reasons that are not completely understood, hematoma formation is followed by slow expansion of the mass...
  70. doi Spontaneous retroperitoneal hematoma: etiology, characteristics, management, and outcome
    Kharmene L Sunga
    Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Emerg Med 43:e157-61. 2012
    Spontaneous retroperitoneal hematoma (SRH) can be fatal, requiring immediate recognition and intervention. Current literature is limited, providing little direction in patient care.
  71. doi Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis
    Methodius G Tuuli
    Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
    Obstet Gynecol 117:1205-12. 2011
    To estimate the association between subchorionic hematoma and adverse perinatal outcomes.
  72. ncbi Intestinal obstruction due to spontaneous intramural hematoma of the small intestine during warfarin use: a report of two cases
    Mehmet Ali Uzun
    General Surgery Department, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
    Eur J Emerg Med 14:272-3. 2007
    Warfarin-dependent spontaneous intramural hematoma of the small intestine is a rare complication. The first symptom is usually abdominal pain, frequently accompanied by nausea and vomiting...
  73. doi Association of serum glucose concentrations during acute hospitalization with hematoma expansion, perihematomal edema, and three month outcome among patients with intracerebral hemorrhage
    Adnan I Qureshi
    Zeenat Qureshi Stroke Research Center, Department of Neurology, University of Minnesota, 12 100 PWB, 516 Delaware St SE, Minneapolis, MN 55455, USA
    Neurocrit Care 15:428-35. 2011
    ..We explored the relationship between various parameters of serum glucose concentrations measured during acute hospitalization and hematoma expansion, perihematomal edema, and three month outcome among subjects with ICH.
  74. ncbi [Expression of matrix metalloproteinase MMP-9 in the plasma and hematoma fluid of intracerebral hemorrhage patients]
    Cheng Han Wu
    Department of Neurology, Second Affiliated Hospital of Fujian College of Traditional Chinese Medicine, Fuzhou 350003, China
    Zhonghua Yi Xue Za Zhi 88:174-6. 2008
    ..To investigate the matrix metalloproteinase (MMP)-9 played in secondary brain injury following intracerebral hemorrhage (ICH)...
  75. doi Right paracardiac mass due to organized pericardial hematoma around retained epicardial pacing wires following aortic valve replacement
    Aditya Kapoor
    Department of Cardiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    Interact Cardiovasc Thorac Surg 13:104-6. 2011
    ..We describe a rare case of right paracardiac mass due to organized pericardial hematoma with right atrial compression around the epicardial pacing wires left in-situ, presenting three months following ..
  76. doi Medicinal leeches for the treatment of venous congestion and hematoma after plastic reconstructive surgery
    Friederike Riede
    Department of Dermatology, Venereology and Allergy, University of Heidelberg, University Medicine Mannheim, Germany
    J Dtsch Dermatol Ges 8:881-8. 2010
    ..In recent years the use of medicinal leeches became rather popular again, e. g. to improve blood circulation in ischemic tissue after reconstructive plastic surgery...
  77. doi Mandibular hematoma cells as a potential reservoir for osteoprogenitor cells in fractures
    Takumi Hasegawa
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
    J Oral Maxillofac Surg 70:599-607. 2012
    We hypothesized that cells within the mandibular fracture hematoma played an important role in mandibular fracture healing. The objective of this study was to analyze cells in human mandibular fracture hematoma.
  78. ncbi Intraorbital hematoma after removal of upper third molar: a case report
    Gary Warburton
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    J Oral Maxillofac Surg 64:700-4. 2006
  79. ncbi Chronic expanding hematoma in the psoas muscle
    Toshinari Yamasaki
    Department of Urology, Himeji Medical Center, Hyogo, Japan
    Int J Urol 12:1063-5. 2005
    We report an unusual case of chronic expanding hematoma in the psoas muscle. A 53-year-old man was admitted for evaluation of a mass shadow in the left lower lung field on chest X-rays. He had also been suffering from dull left back pain...
  80. ncbi Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement
    Soon Tae Lee
    Department of Neurology, Stroke and Neural Stem Cell Laboratory in Clinical Research Institute, Stem Cell Research Center, Seoul National University Hospital, Seoul, South Korea
    J Cereb Blood Flow Metab 26:536-44. 2006
    Glutamate is accumulated in abundance during the early period of experimental hematoma, and the activation of N-methyl-D-aspartate (NMDA) receptors by glutamate can result in an influx of calcium and neuronal death in cases of ..
  81. doi Time course of early postadmission hematoma expansion in spontaneous intracerebral hemorrhage
    Christian Ovesen
    From the Department of Neurology C O, S R, H C and Radiology A F C, I H, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark and Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark D W K
    Stroke 45:994-9. 2014
    Early hematoma expansion (EHE) in patients with intracerebral hematoma is a promising treatment target. To date, the time course of EHE has remained poorly described. We prospectively investigated the time course of EHE.
  82. ncbi Case report: chronic expanding hematoma in the adrenal gland with pathologic correlations
    Takayuki Yamada
    Department of Diagnostic Radiology, Tohoku University, School of Medicine, Miyati, Japan
    J Comput Assist Tomogr 27:354-6. 2003
    We report a case of chronic expanding hematoma in the adrenal gland. Mixed signal intensity in a mosaic pattern was seen on T2-weighted images. A focal area suggesting a subacute hematoma was also noted...
  83. ncbi Retroperitoneal hematoma caused by a ruptured pelvic varix in a patient with iliac vein compression syndrome
    Sachin Dheer
    Department of Radiology, Inova Fairfax Hospital, Falls Church, Virginia, USA
    J Vasc Interv Radiol 14:387-90. 2003
    ..The authors describe an unusual case of IVCS in which the patient presented with a left-sided retroperitoneal hematoma arising from a ruptured collateral venous varix shortly after the development of symptomatic left lower-extremity ..
  84. ncbi Retropericardial hematoma complicating off-pump coronary artery bypass surgery
    Toshihiro Fukui
    Department of Cardiovascular Surgery, Osaka City University Medical School, Osaka, Japan
    Ann Thorac Surg 73:1629-31. 2002
    We report the case of a retropericardial hematoma after triple-vessel off-pump coronary artery bypass grafting...
  85. ncbi Usefulness of the initial noninvasive imaging study to predict the adverse outcomes in the medical treatment of acute type A aortic intramural hematoma
    Jong Min Song
    Division of Cardiology, Asan Medical Center, University of Ulsan, College of Medicine, 388 1 Poongnap dong, Songpa Ku, Seoul 138 040 South Korea
    Circulation 108:II324-8. 2003
    ..have been contradictory reports about the outcomes of medically treated patients with type A aortic intramural hematoma (AIH), and it is not certain if the initial noninvasive imaging studies can provide any useful predictors for the ..
  86. doi Comparisons of 2/3Sh estimation technique to computer-assisted planimetric analysis in epidural, subdural and intracerebral hematomas
    Kai Jun Zhao
    Department of Neurosurgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, China
    Neurol Res 32:910-7. 2010
    ..suitable for the estimation of the epidural, acute subdural, most intracerebral and even some chronic subdural hematoma volume, but its accuracy was prone to be affected by some particular shapes of hematomas...
  87. doi Outcomes of patients with acute type a aortic intramural hematoma
    Jae Kwan Song
    Asan Medical Center, University of Ulsan College of Medicine, 388 1 Poongnap dong Songpa gu, Seoul, 138 736 South Korea
    Circulation 120:2046-52. 2009
    The proper treatment option for patients with type A intramural hematoma (IMH), a variant form of classic aortic dissection (AD), remains controversial...
  88. ncbi Dermoscopy of subcorneal hematoma
    Iris Zalaudek
    Department of Dermatology, University of Graz, Graz, Austria
    Dermatol Surg 30:1229-32. 2004
    Subcorneal hematoma is a pigmented skin lesion usually occurring on palms or soles after a trauma or sport activity...
  89. ncbi Spontaneous subcapsular splenic hematoma: a rare complication of pancreatitis
    Vijaykumar G Patel
    Department of Surgery, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am Surg 71:1066-9. 2005
    Subcapsular hematoma of the spleen is a rare complication of pancreatitis despite its close proximity to the pancreas...
  90. ncbi Intramural hematoma of the cecum as the lead point of intussusception in an elderly patient with hemophilia A: report of a case
    Yoshifumi Nakayama
    Department of Surgery 1, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahata nishi ku, Kita Kyushu, 807 8555, Japan
    Surg Today 36:563-5. 2006
    ..Hemophilia A is a congenital bleeding disorder characterized by a deficiency of coagulation factor VIII. Intramural hematoma of the colon is a very rare complication of this disease...
  91. ncbi Massive retroperitoneal hematoma during enoxaparin treatment of pulmonary embolism after primary total hip arthroplasty: case reports and review of the literature
    Mark C Lee
    Brown University Department of Orthopaedics, Cooperative Care Building, Providence, Rhode Island 02908, USA
    J Arthroplasty 21:1209-14. 2006
    ..This article presents the first case of massive retroperitoneal hematoma during enoxaparin treatment of pulmonary embolism after a primary total hip arthroplasty and discusses several ..
  92. doi Risk of hematoma complications after device implant in the clopidogrel era
    Ilana B Kutinsky
    Department of Cardiovascular Medicine, William Beaumont Hospital, 3601 West 13 Mile Road, Royal Oak, MI 48073, USA
    Circ Arrhythm Electrophysiol 3:312-8. 2010
    Device implant pocket hematoma is a recognized complication after permanent pacemaker (PM) and implantable cardioverter-defibrillator (ICD) implantation...
  93. ncbi New development of an ulcerlike projection in aortic intramural hematoma: CT evaluation
    Eijun Sueyoshi
    Department of Radiology, Omura Municipal Hospital, Japan
    Radiology 224:536-41. 2002
    To investigate the natural history and predictors of progression of a newly developed ulcerlike projection in patients with an aortic intramural hematoma.
  94. ncbi Fracture hematoma is a potent proinflammatory mediator of neutrophil function
    Marcus Timlin
    Departments of Orthopaedics, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
    J Trauma 58:1223-9. 2005
    ..This study was designed to evaluate in vitro the proinflammatory properties of fracture hematoma (FH).
  95. ncbi Late sciatic nerve palsy caused by hematoma after primary total hip arthroplasty
    Matthew S Austin
    Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    J Arthroplasty 19:790-2. 2004
    A case of late sciatic nerve palsy caused by subfascial hematoma after uncemented right total hip arthroplasty is reported...
  96. ncbi Intracerebral hematoma from aneurysm rupture
    Khalid M Abbed
    Department of Neurosurgery, Cerebrovascular Surgery, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts 02114, USA
    Neurosurg Focus 15:E4. 2003
    Patients who present with an intraparenchymal hematoma associated with a ruptured aneurysm usually require urgent clot evacuation and aneurysm obliteration. The impact of the presence of hematoma on outcome has been poorly characterized...
  97. doi Hematoma rates in drainless deep-plane face-lift surgery with and without the use of fibrin glue
    Richard Zoumalan
    Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology Head and Neck Surgery, Lenox Hill Manhattan Eye, Ear, and Throat Hospital, NY, NY, USA
    Arch Facial Plast Surg 10:103-7. 2008
    To determine the rate of hematoma formation in drainless deep-plane rhytidectomy and compare it with the rate using the same technique with the use of fibrin glue.
  98. ncbi Meta-analyses of intracerebral hematoma treatment
    Ihsan Anik
    Kocaeli University, Faculty of Medicine, Department of Neurosurgery, Kocaeli, Turkey
    Turk Neurosurg 21:6-14. 2011
    ..this study is to define the position of surgery preference in the treatment choice for spontaneous intracerebral hematoma (ICH) and to compare the efficacy of surgery with the medical treatment based on data from 18 previously reported ..
  99. ncbi The hematoma block an effective alternative for fracture reduction in distal radius fractures
    Neritan Myderrizi
    University Service of Surgery, Orthopedic Clinic, Regional Hospital Durres, Albania
    Med Arh 65:239-42. 2011
    An alternative to general anesthesia was tested against hematoma block by a double-blind, randomized clinical trial in reduction of Colles fracture.
  100. ncbi Acute femoral neuropathy secondary to an iliacus muscle hematoma
    M Seijo-Martinez
    Neurology Service, Complexo Hospitalario de Pontevedra, Loureiro Crespo s n, Pontevedra 36 001, Spain
    J Neurol Sci 209:119-22. 2003
    We present a patient with a spontaneous iliacus muscle hematoma, appearing immediately after a minor physical maneuver, presenting with pain and femoral neuropathy initially evidenced by massive quadriceps muscle fasciculations...
  101. ncbi Vulvar hematoma following a transobturator sling (TVT-O)
    Stephen R Richards
    Womankind Health and Wellness, 6100 E Main St, Suite 105, Columbus, OH 43213, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:672-3. 2006
    ..Reported is a patient who underwent a tension-free vaginal tape obturator (inside-to-out) procedure and who developed a vulvar hematoma.

Research Grants63

  1. MECHANISMS OF BRAIN EDEMA AFTER INTRACEREBRAL HEMORRHAGE
    Guohua Xi; Fiscal Year: 2009
    ..If the patient survives the ictus, the resulting hematoma within the brain parenchyma triggers a series of events leading to secondary insults and severe neurological ..
  2. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..infection, intra-abdominal abscess formation and septicemia, b) late bleeding or secondary hemorrhage or hematoma;c) urine leak;d) damage to the kidney parenchyma evident by compromised renal function or long term renal ..
  3. Emergency Neurophysiological Assessment Bedside Logic Engine
    Don M Tucker; Fiscal Year: 2010
    ..Many forms of neurological injury, such as hematoma or nonconvulsive seizure, are difficult to diagnose in the emergency room, and yet this is the point at which ..
  4. Effect of Inducible Antioxidants on Hemoglobin Toxicity
    Raymond F Regan; Fiscal Year: 2010
    ..that hemoglobin (Hb) release from lysing erythrocytes may contribute to oxidative injury to tissue surrounding a hematoma. Prior studies have demonstrated that Hb toxicity is mediated by transfer of its heme moieties to nearby cells, ..
  5. Systemic Application for Injury Site Specific Delivery via Neutrophils to Treat B
    XUDONG J LI; Fiscal Year: 2013
    ..However, the risks of epidural injections include, but are not limited to, epidural hematoma, epidural infection, nerve root injury, dural puncture, air embolism and vasovagal syncope...
  6. Pleiotropic Transcription Factors As Target For Intracerebral Hemorrhage Treatmen
    Jaroslaw A Aronowski; Fiscal Year: 2012
    ..stress, inflammation, and protect brain cells from damage, while Nrf2 gene deletion has the opposite effect;(2) Hematoma resolution: Activators of Nrf2 promote phagocytosis by brain microglia/macrophages and accelerate hematoma ..
  7. Low-cost handheld medical device for neuroaxial anesthesia guidance in the obese
    FRANK WILLIAM MAULDIN; Fiscal Year: 2012
    ..e. 40% - 80%) resulting in numerous health complications: headache, hematoma, backpain, vascular puncture, pleural puncture, pneumothorax, and paralysis...
  8. Endogenous Hemoglobin And Heme Detoxification After Intracerebral Hemorrhage
    Xiurong Zhao; Fiscal Year: 2013
    ..and absorption of the hemolytic products (Hb and heme) is an important clinical challenge and critical for hematoma resolution...
  9. Role of Hyperglycemia in Intracerebral Hemorrhage
    Edward P Feener; Fiscal Year: 2013
    ..of symptomatic ICH in stroke patients treated with intravenous tissue plasminogen activator (tPA), and increased hematoma volume and expansion, which are significant and independent determinants of poor clinical outcomes...
  10. Protective Effect of Hemin Preconditioning after Intracerebral Hemorrhage
    Raymond F Regan; Fiscal Year: 2013
    ..A growing body of experimental evidence supports the hypothesis that release of hemin from the hematoma may contribute to oxidative cell injury in adjacent tissue...
  11. Combined Therapy for Intracerebral Hemorrhage Treatment
    Kenneth R Wagner; Fiscal Year: 2013
    ..Additionally, we previously demonstrated that early surgical hematoma removal in our lobar ICH model markedly reduced perihematomal edema and protected the blood-brain-barrier (BBB)...
  12. A Nanofibrous Bioactive Hemodialysis Access Graft
    SAIF G PATHAN; Fiscal Year: 2013
    ..BioAccess grafts will be evaluated for patency, infection-resistance, gross hematoma formation, surface thrombus formation and hyperplasia formation after being punctured various times for 30 and 60 ..
  13. Simvastatin treatment of experimental intracerebral hemorrhage
    DONALD M SEYFRIED; Fiscal Year: 2010
    ..Local effects from the hematoma such as cerebral edema and altered cerebral blood flow will be measured by MR imaging, and the results of statin ..
  14. Ultrasound application in treatment of intra-cranial hemorrhage
    DOUGLAS R HANSMANN; Fiscal Year: 2010
    ..ICH) is caused by a rupture of vessels which bleed directly into the brain tissue, forming a gradually enlarging hematoma (pooling of blood)...
  15. A fluorescent method to quantify neuronal injury after intracerebral hemorrhage
    Raymond F Regan; Fiscal Year: 2012
    ..Although injury to tissue surrounding a hematoma was initially attributed to its mass effect, experimental evidence suggests that the hematoma per se may be toxic ..
  16. Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II)
    ADNAN IQBAL QURESHI; Fiscal Year: 2013
    ..beneficial effect of intensive treatment is presumably mediated through reduction of the rate and magnitude of hematoma expansion observed in approximately 73% of patients with acute ICH...
  17. Therapeutic Window for Acute Stroke Therapy (P50)
    Brett C Meyer; Fiscal Year: 2012
    ..intracerebral hemorrhages to determine the sensitivity and specificity of CT angiography for the prediction of hematoma growth and to test the feasibility of CT angiography for the guidance of hemostatic therapy...
  18. Traumatic Brain Injury Clinical Trials Network
    Howard M Eisenberg; Fiscal Year: 2010
    ..While the concept is simplistic it has the advantage of potentially mitigating brain swelling without hematoma or contusion, despite the specific mechanism or mechanisms of secondary injury active at any particular time ..
  19. Predictors of hematoma expansion in acute intracerebral hemorrhage
    Joshua N Goldstein; Fiscal Year: 2013
    ..Intracerebral hemorrhage (ICH) is the most fatal form of stroke, and no proven therapies are available. Hematoma expansion is the most feared complication of this disease, and therapies targeting this expansion are likely to ..
  20. Minimally Invasive Navigated Brain Hematoma Evacuation with Ultrasound Monitoring
    Michael Y Oh; Fiscal Year: 2010
    ..who are not good candidates for aggressive medical management, new options for surgical evacuation of the hematoma are required in order to reduce these morbidity and mortality rates...
  21. Deferoxamine therapy for intracerebral hemorrhage
    Guohua Xi; Fiscal Year: 2010
    ..If the patient survives the ictus, the resulting hematoma within brain parenchyma triggers a series of events leading to secondary insults and severe neurological deficits...
  22. Statistical and Data Coordinating Center for the ATACH - 2
    Yuko Y Palesch; Fiscal Year: 2013
    ..this expected beneficial effect of intensive treatment is mediated through reduction of the rate and magnitude of hematoma expansion observed in approximately 38% of patients with acute ICH...
  23. Diagnostic Utility of MRI in Intracerebral Hemorrhage
    CHRISTINE A WIJMAN; Fiscal Year: 2010
    ..investigate the diagnostic yield of Magnetic Resonance Imaging (MRI) in both the acute and chronic phase of the hematoma, including the evaluation of novel MRI sequences...
  24. SCORE-IT: The CTA Spot Sign Score in Acute Cerebral Hemorrhage
    Jonathan Rosand; Fiscal Year: 2013
    ..and while there are currently no proven treatments for acute ICH, the observation that continued bleeding and hematoma growth commonly occur points to an inviting therapeutic target...
  25. CD47 and hematoma clearance in intracerebral hemorrhage
    Ya Hua; Fiscal Year: 2013
    ..If the patient survives the ictus, the resulting hematoma within the brain parenchyma triggers a series of events leading to secondary insults and severe neurological ..
  26. Analyses of gradient echo MRI data
    Yi Wang; Fiscal Year: 2013
    ..is well known to have blooming susceptibility artifacts that make it difficult to identify the true boundary of hematoma and overestimate hematoma volume, a critical parameter in managing ICH patients...
  27. EARLY HEMICRANIECTOMY TO MANAGE TRAUMATIC BRAIN INJURY
    William Coplin; Fiscal Year: 1999
    ..Coma Scale score less than or equal to 9, with midline shift greater than the size of a surgically removable hematoma. Group I will receive standardized hemicraniectomy; Group II will undergo traditional craniotomy with or without ..
  28. University of Texas Specialized Program in Acute Stroke
    Sean I Savitz; Fiscal Year: 2012
    ..that first discovered that PPAR gamma agonists promoted the phagocytosis of the red blood cells comprising the hematoma. Project 2 is a direct clinical translation of that work...
  29. Recanalization Therapies and Markers of Stroke Outcome
    JOSEPH PAUL BRODERICK; Fiscal Year: 2012
    ..study of 184 subjects that examines the ability of contrast extravasation on CT angiography (CTA) to predict hematoma growth in patients with intracerebral hemorrhage and to explore the role CTA may play in treatment allocation ..
  30. MR IMAGING OF HEMORRHAGE
    Keith Thulborn; Fiscal Year: 1992
    ..the hemorrhage will be used to study the time dependent evolution of iron-containing substances within the hematoma, including determination of biochemical form, concentration, and spatial distribution...
  31. Therapeutic targeting of CD36 after intracerebral hemorrhage
    Krishnan M Dhandapani; Fiscal Year: 2013
    ..ICH is caused by a ruptured blood vessel within the brain, leading to the formation of a space occupying hematoma. Hematoma volume is clinically associated with neurological deterioration and higher mortality;however, many ICH ..
  32. NONINVASIVE DEVICE FOR SEALING VASCULAR ACCESS PUNCTURES
    Thomas Anderson; Fiscal Year: 2001
    ..These procedures are not performed without risk, and a number of complications such as hematoma, pseudoaneurysm, and arteriovenous fistula occur that are responsible for considerable morbidity and some ..
  33. Antihypertensive Treatment in Acute Cerebral Hemorrhage
    Adnan Qureshi; Fiscal Year: 2006
    ..Although early evidence suggests that acute hypertension (HTN) may predispose to hematoma expansion, the effect of aggressive treatment of acute HTN is yet to be determined...
  34. Role of NADPH Oxidase in ICH-Induced Brain Injury
    Jiping Tang; Fiscal Year: 2006
    ..Our central hypothesis is that ICH elevates NADPH oxidase in the peri-hematoma area, which results in oxidative stress, leading to early brain injury (i.e...
  35. NON-INVASIVE PNEUMOTHORAX DETECTOR
    ALAN GRESZLER; Fiscal Year: 2009
    ..The combined market for these applications is quite large. With further development, the device may be able to detect other trauma conditions, such as hematoma and hemorrhagic stroke.
  36. Genetic Risks for Medication-Related Hemorrhagic Stroke
    Steven Greenberg; Fiscal Year: 2007
    ..determinants of ICH outcome, we will also analyze the ICH cohort, prospectively, for the effects of genotype on hematoma volume, hematoma expansion, patient mortality, and functional status...
  37. ASSOCIATION OF NIPPLE ASPIRATES WITH CLINICAL FINDINGS
    Edward Sauter; Fiscal Year: 2001
    ..Each procedure has the risk of hematoma formation and infection...
  38. Blood Pressure and Risks of Cardiac Catheterization
    Cheryl Dumont; Fiscal Year: 2005
    ..Complications in this study are: hematoma, bleeding, arteriovenous fistula, pseudoaneurysm, retroperitoneal bleed, and vascular occlusion...
  39. TREATMENT OF PHYSIOLOGICAL DISTURBANCES IN HEAD INJURY
    Robert Grossman; Fiscal Year: 1993
    ..These secondary processes include ischemia, hyperemia, edema, hypermetabolism, acidosis, inflammation and delayed hematoma formation...
  40. Genetic Determinants of Hematoma Volume
    Jonathan Rosand; Fiscal Year: 2006
    ..The objectives of this proposal are to determine 1) whether APOE predicts large hematoma volume in acute ICK, acute hematoma enlargement, and poor clinical outcome from acute ICH, and 2) whether factor ..
  41. A Novel Protection Device for Shock Wave Lithotripter
    Jian Zhang; Fiscal Year: 2005
    ..However, SWL also causes acute renal injury, such as hemorrhage, hematoma, edema and enlargement of kidney...
  42. A Novel Handheld Three-Dimensional Camera for Wound Healing Monitoring
    STEVEN YI; Fiscal Year: 2009
    ..would be particularly useful in helping clinicians assess healing status and judge the effect of hyperemia, hematoma, local inflammation, secondary infection, and tissue necrosis...
  43. Azulenyl nitrones: neuroprotectants in stroke and trauma
    MYRON GINSBERG; Fiscal Year: 2006
    ..TBI studies will be performed in the standard moderate-to-severe fluid percussion model. Striatal intracerebral hematoma is produced by double blood injection...
  44. PRENATAL COCAINE EXPOSURE & CNS FUNCTION IN ADULT RATS
    SHELDON SPARBER; Fiscal Year: 1992
    ..g. subdural hematoma or other evidence of CVA or seizures)...
  45. INFLAMMATION AND APOPTOSIS IN INTRACEREBRAL HEMORRHAGE
    Mark Grossetete; Fiscal Year: 2005
    ..proteolytically degrades the blood-brain barrier, results in the coalescing of multifocal hemorrhages into a hematoma that models hemorrhagic transformation (HT)...
  46. NON-INVASIVE PNEUMOTHORAX DETECTOR
    FRANK DIFILIPPO; Fiscal Year: 2000
    ..With further development, the device may be tuned to detect other trauma conditions, such as hematoma and hemorrhagic stroke.
  47. CLINICAL TEST OF NIR/PRM SENSOR FOR HEAD INJURY DIAGNOSI
    Hyo Lee; Fiscal Year: 1999
    ..needed for clinical applications, we will design and develop an instrument whose performance is optimized for hematoma detection...
  48. Pparg In Macrophage Promote Hematoma Absorption After Intracerebral Hemorrhage
    Xiurong Zhao; Fiscal Year: 2008
    ..Even though patients survive the ictus, the resulting hematoma within brain parenchyma, triggers a series of events leading to secondary insults and severe neurological ..
  49. Cerebral Hemorrhage Model: Mechanisms and Treatments
    Kenneth Wagner; Fiscal Year: 2005
    ..abstract_text> ..
  50. Etiology of cellular damage after experimental stroke
    Jaroslaw Aronowski; Fiscal Year: 2005
    ..These laboratory studies in animal models of hemorrhage and infarction will provide the framework for developing a possible new approach to therapy for stroke in humans. ..
  51. THE ROLE OF LYMPHOCYTES IN CEREBRAL ISCHEMIC INJURY
    Kyra Becker; Fiscal Year: 2004
    ....
  52. CNS antigen sensitization in stroke.
    Kyra Becker; Fiscal Year: 2009
    ..Data derived from this study will be used to plan future trials of immunomodulation in patients with stroke. ..
  53. Novel treatment for stroke:
    Jaroslaw Aronowski; Fiscal Year: 2005
    ..This study should provide the necessary information to translate our experimental results with this novel and potentially useful drug combination to clinical therapeutic trials in human stroke patients. ..
  54. New Target For Stroke: Peroxisome Proliferator Activated Receptor-Gamma
    Jaroslaw Aronowski; Fiscal Year: 2008
    ..3. To evaluate optimal conditions (selection of drug, dose, time window for effective treatment, tolerance, and effectiveness in permanent vs. reversible ischemia) for the anti-ischemic activity of PPARy agonists. ..
  55. Delayed Neurodegeneration After Intracerebral Hemorrhage
    Guohua Xi; Fiscal Year: 2007
    ..If the patient survives the ictus, the resulting hematoma within brain parenchyma triggers a series of events leading to secondary insults and severe neurological deficits...
  56. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2009
    ..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
  57. ADIPOSE DERIVED STEM CELLS FOR TREATMENT OF INCONTINENCE
    LARISSA RODRIGUEZ; Fiscal Year: 2008
    ..Lastly, we will use an animal model of incontinence and decreased urethral resistance to test the hypothesis that these cells can be used to reconstruct a functional urethra as a treatment of stress incontinence. ..
  58. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2002
    ..abstract_text> ..
  59. TEM with Digital and Cryopreparation Systems
    Andrew Evan; Fiscal Year: 2003
    ..Dr. Richard Gregory will employ immunohistochemistry to examine the role of a Streptococcus mutans 65 kDa fimbrial protein binding as a mechanism for the induction of dental carries. ..
  60. Evaluation of Antioxidant Suppl in Focal CNS Ischemia
    Wayne Clark; Fiscal Year: 2003
    ..The information obtained from this project will be critical in planning future clinical stroke trials involving these agents. ..
  61. Gene Discovery in Heritable Renal Hypodysplasia
    Scott Lozanoff; Fiscal Year: 2007
    ..This sequence will be subjected to a mouse-human homology search and it is likely that a corresponding human gene will be identified since distal murine chr17 shares a high degree of sequence affinity with human chr 2p21.1. ..
  62. Oral Care and Respiratory Pathogen Colonization
    Ozan Akca; Fiscal Year: 2004
    ..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
  63. Clinical trial design and analysis in traumatic brain injury
    Andrew Maas; Fiscal Year: 2009
    ..IMPACT: International Mission on Prognosis and Analysis of Clinical Trials in TBI. ..