catastrophic illness

Summary

Summary: An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly.

Top Publications

  1. ncbi Catastrophic antiphospholipid syndrome: lessons from the "CAPS Registry"--a tribute to the late Josep Font
    Ricard Cervera
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain
    Ann N Y Acad Sci 1108:448-56. 2007
  2. ncbi Household catastrophic health expenditure: a multicountry analysis
    Ke Xu
    Evidence and Information for Policy, World Health Organization, 20 Avenue Appia, CH 1211 27, Geneva, Switzerland
    Lancet 362:111-7. 2003
  3. ncbi Catastrophe and impoverishment in paying for health care: with applications to Vietnam 1993-1998
    Adam Wagstaff
    The World Bank, Washington, DC 20433, USA
    Health Econ 12:921-34. 2003
  4. pmc Household catastrophic health expenditure: evidence from Georgia and its policy implications
    George Gotsadze
    Curatio International Foundation, 37d, I Chavchavadze ave, Tbilisi, 0179, Georgia
    BMC Health Serv Res 9:69. 2009
  5. ncbi Protecting households from catastrophic health spending
    Ke Xu
    Department of Health Systems Financing, Health Systems and Services, World Health Organization, Geneva, Switzerland
    Health Aff (Millwood) 26:972-83. 2007
  6. ncbi Catastrophic medical payment and financial protection in rural China: evidence from the New Cooperative Medical Scheme in Shandong Province
    Xiaoyun Sun
    Health Department of Shandong Province, Jinan, China
    Health Econ 18:103-19. 2009
  7. ncbi Inequality in household catastrophic health care expenditure in a low-income society of Iran
    Zahra Kavosi
    Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Health Policy Plan 27:613-23. 2012
  8. pmc Household out-of-pocket payments for illness: evidence from Vietnam
    Nguyen Thi Bich Thuan
    Planning and Financing Department of Ministry of Health, Hanoi, Vietnam
    BMC Public Health 6:283. 2006
  9. ncbi Social risk management options for medical care in Indonesia
    Menno Pradhan
    Economic and Social Institute, Free University, Amsterdam, The Netherlands
    Health Econ 11:431-46. 2002
  10. ncbi Examining catastrophic health expenditures at variable thresholds using household consumption expenditure diaries
    Chima A Onoka
    Health Policy Research Group, College of Medicine, University of Nigeria, Enugu, Nigeria
    Trop Med Int Health 16:1334-41. 2011

Research Grants

Detail Information

Publications180 found, 100 shown here

  1. ncbi Catastrophic antiphospholipid syndrome: lessons from the "CAPS Registry"--a tribute to the late Josep Font
    Ricard Cervera
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain
    Ann N Y Acad Sci 1108:448-56. 2007
    ..This registry can be freely consulted at the Internet (www.med.ub.es/MIMMUN/FORUM/CAPS.HTM) and it is expected that the periodical analysis of these data will allow us to increase our knowledge of this condition...
  2. ncbi Household catastrophic health expenditure: a multicountry analysis
    Ke Xu
    Evidence and Information for Policy, World Health Organization, 20 Avenue Appia, CH 1211 27, Geneva, Switzerland
    Lancet 362:111-7. 2003
    ..Yet catastrophic expenditure is not rare. We investigated the extent of catastrophic health expenditure as a first step to developing appropriate policy responses...
  3. ncbi Catastrophe and impoverishment in paying for health care: with applications to Vietnam 1993-1998
    Adam Wagstaff
    The World Bank, Washington, DC 20433, USA
    Health Econ 12:921-34. 2003
    ....
  4. pmc Household catastrophic health expenditure: evidence from Georgia and its policy implications
    George Gotsadze
    Curatio International Foundation, 37d, I Chavchavadze ave, Tbilisi, 0179, Georgia
    BMC Health Serv Res 9:69. 2009
    ....
  5. ncbi Protecting households from catastrophic health spending
    Ke Xu
    Department of Health Systems Financing, Health Systems and Services, World Health Organization, Geneva, Switzerland
    Health Aff (Millwood) 26:972-83. 2007
    ..Prepayment mechanisms protect people from financial catastrophe, but there is no strong evidence that social health insurance systems offer better or worse protection than tax-based systems do...
  6. ncbi Catastrophic medical payment and financial protection in rural China: evidence from the New Cooperative Medical Scheme in Shandong Province
    Xiaoyun Sun
    Health Department of Shandong Province, Jinan, China
    Health Econ 18:103-19. 2009
    ..To measure the impact of China's New Cooperative Medical Scheme (NCMS) on catastrophic medical payments of rural households in Linyi County, Shandong Province...
  7. ncbi Inequality in household catastrophic health care expenditure in a low-income society of Iran
    Zahra Kavosi
    Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Health Policy Plan 27:613-23. 2012
    ..We assessed change in household catastrophic health care expenditures (CHE) and inequality in facing such expenditures in south-west Tehran...
  8. pmc Household out-of-pocket payments for illness: evidence from Vietnam
    Nguyen Thi Bich Thuan
    Planning and Financing Department of Ministry of Health, Hanoi, Vietnam
    BMC Public Health 6:283. 2006
    ..The focus of the paper is on the relative effect of different illnesses on the total economic burden of health care on households in general and on households that have catastrophic health care spending in particular...
  9. ncbi Social risk management options for medical care in Indonesia
    Menno Pradhan
    Economic and Social Institute, Free University, Amsterdam, The Netherlands
    Health Econ 11:431-46. 2002
    ..Subsidizing outpatient treatment is a cost effective policy to reduce exposure to catastrophic risks only for the very poor...
  10. ncbi Examining catastrophic health expenditures at variable thresholds using household consumption expenditure diaries
    Chima A Onoka
    Health Policy Research Group, College of Medicine, University of Nigeria, Enugu, Nigeria
    Trop Med Int Health 16:1334-41. 2011
    ..Using uniform thresholds and a set of variable threshold levels, this study examined the incidence of catastrophe amongst households of different socio-economic status (SES) quintiles...
  11. pmc Comparisons of medical utilizations and categorical diagnoses of emergency visits between the elderly with catastrophic illness certificates and those without
    Yang Nan-Ping
    Institute of Public Health, College of Medicine, National Yang Ming University, Taipei, Taiwan
    BMC Health Serv Res 13:152. 2013
    In Taiwan, the policy of catastrophic illness certificates has benefited some populations with specific diseases, but its effect on the use of medical services and the sequence of public health has not been examined...
  12. ncbi Catastrophic antiphospholipid syndrome (CAPS)
    Savino Sciascia
    Lupus Research Unit, The Rayne Institute, Division of Women s Health, King s College London, UK
    Best Pract Res Clin Rheumatol 26:535-41. 2012
    ..In this article, we aimed to review the state-of-the art about current knowledge in pathogenesis, clinical manifestations, diagnosis and treatment strategies in CAPS...
  13. ncbi Catastrophic health expenditure and impoverishment in Turkey
    Mahmut Saadi Yardim
    Hacettepe University, Faculty of Medicine, Department of Public Health, Sihhiye, Ankara, Turkey
    Health Policy 94:26-33. 2010
    ..This study aims to identify the level of catastrophic health expenditure (CHE) in Turkey and, to reveal household factors predicting this outcome...
  14. ncbi Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of a series of 280 patients from the "CAPS Registry"
    Ricard Cervera
    Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Barcelona, Catalonia, Spain
    J Autoimmun 32:240-5. 2009
    ..To describe the clinical and laboratory features, as well as the precipitating factors, treatment and outcome of patients with catastrophic antiphospholipid syndrome (APS)...
  15. ncbi Health insurance and catastrophic illness: a report on the New Cooperative Medical System in rural China
    Hongmei Yi
    Center for Chinese Agricultural Policy, Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China
    Health Econ 18:S119-27. 2009
    ..The real reimbursement rate for illnesses that required expenditures between 4000 and 10,000 yuan (over 10,000 yuan) was only 11% (8%). Our analysis shows that one of the limiting factors is constrained funding...
  16. ncbi Understanding the impact of eliminating user fees: utilization and catastrophic health expenditures in Uganda
    Ke Xu
    World Health Organization, Geneva, Switzerland
    Soc Sci Med 62:866-76. 2006
    ....
  17. ncbi Laboratory studies on pathophysiology of the catastrophic antiphospholipid syndrome
    Gerard Espinosa
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain
    Autoimmun Rev 6:68-71. 2006
    ....
  18. ncbi The role of therapeutic plasma exchange in the catastrophic antiphospholipid syndrome
    Imad Uthman
    Department of Internal Medicine, Division of Rheumatology, American University of Beirut Medical Center AUBMC, Hamra Street, Beirut 1107 2802, Lebanon
    Transfus Apher Sci 33:11-7. 2005
    ..The use of this technique, along with anticoagulation and if needed pharmacological immunosuppression, should be considered for the acute management of patients who present with this life-threatening condition...
  19. ncbi Update on the diagnosis, treatment, and prognosis of the catastrophic antiphospholipid syndrome
    Ricard Cervera
    Department of Autoimmune Diseases, Servei de Malalties Autoimmunes, Hospital Clinic, Villarroel 170, Barcelona, Catalonia, 08036, Spain
    Curr Rheumatol Rep 12:70-6. 2010
    ..However, once patients with catastrophic APS have recovered, they usually follow a stable course with continued anticoagulation and few patients present with a relapse of the catastrophic episode...
  20. ncbi Determining factors of catastrophic health spending in Bogota, Colombia
    Jeannette Liliana Amaya Lara
    Center for Development Projects Cendex, Pontificia Universidad Javeriana, Carrera 7 No 40 62, Bogota, Colombia
    Int J Health Care Finance Econ 11:83-100. 2011
    ....
  21. ncbi Relationship between catastrophic health expenditures and household incomes and expenditure patterns in South Korea
    Younhee Kim
    National Evidence based Healthcare Collaborating Agency NECA, Seoul, South Korea
    Health Policy 100:239-46. 2011
    ..Also, relationships between catastrophic health expenditures and household incomes, and between such health expenditures and expenditure patterns were explored...
  22. pmc Preventing impoverishment through protection against catastrophic health expenditure
    Kei Kawabata
    Bull World Health Organ 80:612. 2002
  23. pmc Catastrophic health expenditure
    Wim Van Damme
    Lancet 362:996; author reply 997. 2003
  24. pmc Reduction of catastrophic health care expenditures by a community-based health insurance scheme in Gujarat, India: current experiences and challenges
    Michael Kent Ranson
    Health Policy Unit, London School of Hygiene and Tropical Medicine, London, England
    Bull World Health Organ 80:613-21. 2002
    ....
  25. ncbi Measuring financial protection in health in the United States
    Hugh R Waters
    Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room 8132, Baltimore, MD 21205, USA
    Health Policy 69:339-49. 2004
    ..The results are placed in an international context. Similar studies in other countries would allow for more in-depth comparisons of financial protection than are currently possible...
  26. ncbi Catastrophic antiphospholipid syndrome and pulmonary embolism in a 3-year-old child
    Carine Olivier
    Department of Radiology, University Hospital of Rouen, 1 rue de Germont, Rouen, 76031, France
    Pediatr Radiol 36:870-3. 2006
    ..In spite of a relatively rapid diagnosis and multiple treatments, the outcome was unfavourable. Multimodality imaging, including both ultrasonography and spiral CT, allowed close follow-up of the thromboses...
  27. ncbi Intestinal involvement secondary to the antiphospholipid syndrome (APS): clinical and immunologic characteristics of 97 patients: comparison of classic and catastrophic APS
    Ricard Cervera
    Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalonia, Spain
    Semin Arthritis Rheum 36:287-96. 2007
    ..To analyze the clinical and laboratory characteristics of 97 patients with intestinal involvement secondary to the antiphospholipid syndrome (APS) (37 patients with classic APS and 60 with catastrophic APS)...
  28. ncbi Catastrophic antiphospholipid syndrome
    Ricard Cervera
    Department of Autoimmune Diseases, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Rheum Dis Clin North Am 32:575-90. 2006
    ..Additionally, preventive measures in patients with APS may be effective if the development of the catastrophic APS is to be avoided...
  29. ncbi Catastrophic antiphospholipid syndrome in a 14-year-old child
    George Tsirpanlis
    Department of Nephrology, General Hospital of Athens, Athens, Greece
    Pediatr Nephrol 20:519-21. 2005
    ....
  30. pmc Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases
    José A Gómez-Puerta
    Servei de Malalties Autoimmunes, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Ann Rheum Dis 66:740-6. 2007
    ..The catastrophic variant of the antiphospholipid syndrome (APS) is a life-threatening form of presentation of this syndrome that can be triggered by several factors...
  31. ncbi Catastrophic antiphospholipid syndrome; a "CATASTROPHIC" case of systemic lupus erythematosus
    Jefferson R Roberts
    Department of Medicine, Tripler Army Medical Center, Honolulu, HI 96859, USA
    Hawaii Med J 63:362-4. 2004
    ..The overall mortality of CAPS is roughly 50%, but prompt clinical recognition of this rare but devastating syndrome may lead to improved outcomes...
  32. ncbi Treatment of the antiphospholipid antibody syndrome
    Christopher Wu
    Center for Innovative Therapy, UCSD School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0943, USA
    Curr Rheumatol Rep 6:463-8. 2004
    ..A better understanding of the immune mechanisms that govern thrombosis in this syndrome has led to a wide array of innovative treatment approaches that will require meticulous study...
  33. ncbi Catastrophic health payments and health insurance: some counterintuitive evidence from one low-income country
    Bjorn Ekman
    Health Economics Program HEP, Department of Clinical Sciences, Malmo, SE 205 02 Malmo, Lund University, Sweden
    Health Policy 83:304-13. 2007
    ..The purpose of the study is to quantitatively analyze the role of health insurance in the determinants of catastrophic health payments in a low-income country setting...
  34. ncbi Delayed catastrophic antiphospholipid syndrome after massive cerebral infarction
    Wei Hsi Chen
    Neurocritical Care Unit, Department of Neurology, Chang Gung Memorial Hospital Kaohsiung Medical Center, and School of Medicine, Chang Gung University, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung 833, Taiwan
    Neurocrit Care 7:148-51. 2007
    ..Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening disorder urgent for aggressive treatment, and its characterized systemic thromboses and coagulopathy prompt for a rapid diagnosis...
  35. ncbi Catastrophic antiphospholipid syndrome
    Richard Cervera
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain
    Pathophysiol Haemost Thromb 35:181-6. 2006
    ..The combination of high doses of intravenous (iv) heparin, iv steroids, iv gamma globulins and/or repeated plasma exchanges is the basic treatment of choice for all patients with this severe condition...
  36. ncbi Asherson's syndrome
    I Machtey
    Isr Med Assoc J 6:508. 2004
  37. ncbi Catastrophic thromboses and severe thrombocytopenia during heparin therapy in a patient with anti-phospholipid syndrome
    Lior Zeller
    Department of Medicine D, Soroka Medical Center and Ben Gurion University, Beersheba, Israel
    Clin Rheumatol 25:426-9. 2006
    ..The possible role of heparin in induction of thromboses and its therapeutic implication are detailed...
  38. ncbi Catastrophic antiphospholipid syndrome: a rare cause of disseminated microvascular thrombotic injury - a case report with pathological and molecular correlative studies
    Syeling Lai
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
    Pathol Int 55:144-9. 2005
    ..To our knowledge, this is the first CAPS patient with molecular studies for genetic prothrombotic mutations. Our report showed that there was no association between the development of CAPS and inherited thromophilia...
  39. pmc Catastrophic primary antiphospholipid syndrome presenting as status epilepticus
    L J Coward
    J Neurol Neurosurg Psychiatry 76:1607-8. 2005
  40. ncbi [Catastrophic health expenditures in Mexico: comparative study by social exclusion level]
    Raymundo Pérez-Rico
    Dirección General de Evaluación del Desempeño, Secretaria de Salud, Mexico, DF, Mexico
    Salud Publica Mex 47:S47-53. 2005
    ..To describe the differences in catastrophic health expenditures in five Mexican states...
  41. ncbi Lessons from the catastrophic antiphospholipid syndrome (CAPS) registry
    Ricard Cervera
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain
    Autoimmun Rev 6:81-4. 2006
    ..This registry can be freely consulted at the Internet (www.med.ub.es/MIMMUN/FORUM/CAPS.HTM) and it is expected that the periodical analysis of these data will allow us to increase our knowledge of this condition...
  42. ncbi [Catastrophic antiphospholipid syndrome: CAPS]
    Masahide Yamazaki
    Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Division of Hematology
    Nihon Rinsho Meneki Gakkai Kaishi 28:357-64. 2005
    ..IAPP could be an useful treatment skill for CAPS and we have started prospective study...
  43. ncbi Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome
    José A Gómez-Puerta
    Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Barcelona, Catalonia, Spain
    Autoimmun Rev 6:85-8. 2006
    ..In around 6% of the cases, the catastrophic APS can appear during pregnancy or puerperium. We review this specific subset of the catastrophic APS and propose a therapeutical approach for this particular situation...
  44. ncbi Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors
    Silvia Bucciarelli
    Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Barcelona, Catalonia, Spain
    Autoimmun Rev 6:72-5. 2006
    ..According to the results of this analysis, anticoagulation plus steroids plus plasma exchange should be the first line of therapy in patients with catastrophic APS...
  45. ncbi Unusual abdominal manifestations of catastrophic antiphospholipid syndrome
    Daryl C L Tan
    Department of Haematology, Singapore General Hospital, Singapore
    Br J Haematol 132:538. 2006
  46. ncbi Catastrophic antiphospholipid (Asherson's) syndrome and genetic thrombophilic disorders in obstetrics
    A Makatsariya
    Department of Obstetrics and Gynecology of Moscow Medical Academy, Noviy Arbat 7, 119017 Moscow, Russia
    Autoimmun Rev 6:89-93. 2006
    ..Low-molecular-weight heparin is the drug of choice for preventing obstetric complications and CAPS due to its anticoagulant and anti-inflammatory properties...
  47. ncbi Rituximab treatment for resistant antiphospholipid syndrome
    Elyse Rubenstein
    Division of Rheumatology and Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
    J Rheumatol 33:355-7. 2006
    ..Since rituximab infusion, all the patients have had stable platelet counts and no further episodes of bleeding or thromboses...
  48. ncbi The catastrophic antiphospholipid (Asherson's) syndrome and malignancies
    W Miesbach
    Department of Internal Medicine III, University Hospital, Johan Wolfgang Goethe University, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Autoimmun Rev 6:94-7. 2006
    ..Malignancy may be an important risk factor for CAPS. 9% of patients with CAPS presented with an underlying malignancy. In most of these patients, the malignancy and/or surgical procedures were the precipitating factors for CAPS...
  49. ncbi Catastrophic antiphospholipid syndrome presenting with renal thrombotic microangiopathy and diffuse proliferative glomerulonephritis
    J A Gomez-Puerta
    Clin Exp Rheumatol 24:110. 2006
  50. ncbi The clinical spectrum of catastrophic antiphospholipid syndrome in the absence and presence of lupus
    Ulas D Bayraktar
    Interfaith Medical Center, Brooklyn, New York, USA
    J Rheumatol 34:346-52. 2007
    ..To compare the clinical spectrum of patients with primary catastrophic antiphospholipid syndrome (P-CAPS) to those with systemic lupus erythematosus-associated CAPS (SLE-CAPS)...
  51. pmc Refractory leg infection as an inducer of the catastrophic antiphospholipid syndrome
    H Amital
    Rheumatology Unit, Hadassah Medical Centre, Jerusalem, Israel
    Ann Rheum Dis 63:1004; discussion 1004. 2004
  52. ncbi Bone marrow necrosis and refractory HELLP syndrome in a patient with catastrophic antiphospholipid antibody syndrome
    Jayashree Sinha
    Albert Einstein College of Medicine and White Plains Medical Center Bronx New York, USA
    J Rheumatol 29:195-7. 2002
    ..This case illustrates a rarely recognized, potentially fatal complication of aPL in the setting of pregnancy...
  53. ncbi Catastrophic antiphospholipid syndrome associated with typhoid fever: comment on the article by Hayem et al
    Imad Uthman
    Arthritis Rheum 46:850. 2002
  54. ncbi [Intraalveolar hemorrhage as a cause of acute respiratory failure in catastrophic antiphospholipid syndrome]
    E Tuleja

    Pol Arch Med Wewn 106:951-4. 2001
    ..Syndrome of multiorgan failure developed despite the treatment with plasmapheresis, high doses of glycocorticosteroids, an intravenous gammaglobulins. The patient died 6 weeks after the admission...
  55. ncbi Treatment of catastrophic antiphospholipid syndrome with defibrotide, a proposed vascular endothelial cell modulator
    Arsinur Burcoglu-O'Ral
    Department of Hematology and Oncology, University of Pittsburgh, Pennsylvania, USA
    J Rheumatol 29:2006-11. 2002
    ..To define at the molecular level the vascular endothelial cell (VEC) injury characteristics of catastrophic antiphospholipid syndrome (CAPS) and to report successful therapeutic use of a VEC modulator, defibrotide...
  56. ncbi Predictable removal of anticardiolipin antibody by therapeutic plasma exchange (TPE) in catastrophic antiphospholipid antibody syndrome (CAPS)
    T Zar
    Department of Medicine, Division of Nephrology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Clin Nephrol 70:77-81. 2008
    ..The case report and discussion provide valuable insight into aCL AB production and its removal by first- order kinetics using TPE...
  57. doi Plasma exchange for the management of the catastrophic antiphospholipid syndrome: importance of the type of fluid replacement
    P Marson
    J Intern Med 264:201-3. 2008
  58. ncbi Catastrophic antiphospholipid-antibody syndrome and danazol
    B Roca
    Infectious and Immunologic Disease Division, Medicine Department, Hospital General of Castellon, Spain
    J Investig Allergol Clin Immunol 13:209-10. 2003
    ..We report a case of catastrophic antiphospholipid-antibody syndrome, with renal and neurological manifestations, which presented shortly after the institution of danazol for the treatment of refractory thrombocytopenia...
  59. ncbi [Catastrophic antiphospholipid syndrome and acute heart failure. Report of a case]
    Pablo Castro
    Departamento de Enfermedades Cardiovasculares, Hospital Clínico Pontificia Universidad Católica de Chile
    Rev Med Chil 131:1037-41. 2003
    ..After this episode, the patient has been treated with prednisone and oral anticoagulants treatment for the last two years, without further clinical events...
  60. ncbi Catastrophic antiphospholipid syndrome and sepsis. A common link?
    Gerard Espinosa
    J Rheumatol 34:923-6. 2007
  61. ncbi Acute respiratory distress syndrome and other unusual manifestations of the catastrophic antiphospholipid (Asherson's) syndrome
    Ronald A Asherson
    Rheumatic Diseases Unit, Department of Medicine, Faculty of Health Sciences, University of Cape, Cape Town, South Africa
    Isr Med Assoc J 6:360-3. 2004
  62. ncbi Hepatic infarction during pregnancy in catastrophic antiphospholipid syndrome
    Charles Berkelhammer
    J Gastroenterol Hepatol 22:1695-6. 2007
  63. ncbi Catastrophic antiphospholipid syndrome: report of 4 cases
    R A Sinico
    Department of Nephrology, Immunology and Blood Purification, San Carlo Borromeo Hospital, Milan, Italy
    J Nephrol 20:739-44. 2007
    ..Nephrologists should be aware of the possibility of this syndrome as a cause of multiorgan failure since prompt recognition is essential for effective treatment...
  64. ncbi Steroid-responsive catastrophic antiphospholipid syndrome
    Adam Gordon
    J Gastroenterol Hepatol 19:479-80. 2004
  65. ncbi Chronic hip pain in a boy with mental retardation and cerebral palsy
    Martin T Stein
    University of California San Diego, Children s Hospital San Diego, CA, USA
    J Dev Behav Pediatr 31:S86-91. 2010
    ..Although the parents continue to believe that the HIB vaccine caused his catastrophic illness, they remain with the pediatrician...
  66. ncbi Toward the early diagnosis of neonatal sepsis and sepsis-like illness using novel heart rate analysis
    M P Griffin
    Department of, and Molecular Physiology and Biological Physics, and the Cardiovascular Research Center, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    Pediatrics 107:97-104. 2001
    ..of morbidity and mortality in neonates, and earlier diagnosis should improve therapy of this potentially catastrophic illness. In practice, clinical signs and laboratory data have not been perceived as sensitive or specific for early ..
  67. ncbi Acute liver failure
    Murali Pathikonda
    Temple School of Medicine 3401 N Broad Street, Boyer Building, Suite 473, Philadelphia, Pennsylvania 19140, USA
    Ann Hepatol 9:7-14. 2010
    Acute liver failure is a rare but often catastrophic illness affecting the liver and multiple organ systems. Patients with acute liver failure require a multidisciplinary approach for adequate management...
  68. ncbi Liberation from prolonged mechanical ventilation
    David J Scheinhorn
    Barlow Respiratory Research Center, 2000 Stadium Way, Los Angeles, CA 90026, USA
    Crit Care Clin 18:569-95. 2002
    ..A prolonged recovery period after catastrophic illness is the rule, with multidisciplinary rehabilitation and discharge planning efforts...
  69. ncbi Malignancies associated with dermatomyositis and polymyositis in Taiwan: a nationwide population-based study
    Y L Huang
    Department of Dermatology, National Yang Mind University, Taipei, Taiwan
    Br J Dermatol 161:854-60. 2009
    ..Previous studies showed that idiopathic inflammatory myopathies (IIM) carried an increased risk of cancers. However, no large-scale study of IIM has been conducted in the Chinese population...
  70. ncbi [Transference and countertransference in medically ill patients]
    Mine Ozmen
    Istanbul U Cerrahpaşa Tip Fak, Psikiyatri Bl, Istanbul, Turkey
    Turk Psikiyatri Derg 18:72-9. 2007
    ..There is always a risk of either avoidance or over involvement with the patient, especially in cases of catastrophic illness or injury...
  71. ncbi The cognitive-behavioral model of hypochondriasis: misinformation and triggers
    D K Marcus
    Department of Psychology, Sam Houston State University, Huntsville, Texas 77341 2447, USA
    J Psychosom Res 47:79-91. 1999
    ..Estimates of the likelihood of catastrophic illness and self-esteem independently contributed to the prediction of hypochondriacal concerns...
  72. ncbi An international feasibility study of parental decision making in pediatric oncology
    P S Hinds
    Divison of Patient Care Services, St Jude Children s Research Hospital, Memphis, TN, USA
    Oncol Nurs Forum 27:1233-43. 2000
    ..To describe parental decision making about treatment options for children with cancer and determine the feasibility of a similar but larger international study...
  73. ncbi The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases
    Eric J Boren
    University of California at Davis School of Medicine, Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, 451 Health Sciences Drive, Suite 6510, Davis, CA 95616, USA
    J Autoimmun 30:90-8. 2008
    ..PML has now emerged as a catastrophic illness in multiple sclerosis with biologic drug therapy (natalizumab) and reported in rheumatic diseases with and ..
  74. ncbi Possible objectives and resulting entitlements of essential health care packages
    N Soderlund
    Centre for Health Policy, University of the Witwatersrand, Johannesburg, South Africa
    Health Policy 45:195-208. 1998
    ..Eight possible objectives for an essential benefit package are described: To protect against catastrophic illness events; to ensure social risk pooling; to improve allocative efficiency in the health system; to eliminate '..
  75. ncbi Massive rhabdomyolysis and multiple organ dysfunction syndrome caused by leptospirosis
    D B Coursin
    Department of Anesthesiology, University of Wisconsin Medical School, Madison 53792, USA
    Intensive Care Med 26:808-12. 2000
    ..An in-depth work-up for causes of this catastrophic illness confirmed acute leptospirosis...
  76. ncbi Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients
    S Baize
    Centre International de Recherches Medicales de Franceville, Gabon
    Nat Med 5:423-6. 1999
    ..Thus, events very early in Ebola virus infection determine the control of viral replication and recovery or catastrophic illness and death.
  77. ncbi HIV as a chronic disease
    Tabitha W Mahungu
    Department of HIV Medicine, Royal Free NHS Trust, London
    Clin Med 9:125-8. 2009
    The 25th anniversary of the first reports of a catastrophic illness later classified as AIDS and the 10th anniversary of highly active antiretroviral therapy (HAART) both occurred in 2006...
  78. ncbi Survivors of catastrophic illness: outcome after direct transfer from intensive care to extended care facilities
    S A Nasraway
    Department of Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Crit Care Med 28:19-25. 2000
    ..To describe outcomes of adult survivors of prolonged critical illness after direct transfer to extended care facilities...
  79. ncbi False expectations? Expectations vs. probabilities for dying
    C M Smith
    University of Arizona, Department of Anthropology, Tucson, AZ 85721 0030, USA
    Omega (Westport) 41:157-85. 2000
    ..Instead, when conversations about death were reported, they had been largely limited to the scenarios of catastrophic illness (e.g., hospitalization, ventilator, etc.) and the Living Will...
  80. pmc Senescence effects in an extremely long-lived bird: the grey-headed albatross Thalassarche chrysostoma
    Paulo Catry
    British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
    Proc Biol Sci 273:1625-30. 2006
    ..suggest that birds could maintain a high level of physical fitness until old age, before being struck by a catastrophic illness leading quickly to their demise...
  81. ncbi Acute liver failure caused by hepatitis E virus and paracetamol
    S KC
    Liver Unit, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal
    JNMA J Nepal Med Assoc 46:74-6. 2007
    ..This catastrophic illness can rapidly progress to coma and death from cerebral edema and multi organ dysfunction...
  82. ncbi Comparison between hospital-based and community-based services for the special health care needs of children with developmental delays
    Jannie Ying Syuan Chen
    Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Chang Gung Med J 33:164-73. 2010
    ..Recognizing special health care needs (SHCN) is obligatory for children with developmental delay (DD). The purpose of this study was to compare hospital-based and community-based services for the SHCN of children with DD...
  83. ncbi Treatment-seeking behaviour, cost burdens and coping strategies among rural and urban households in Coastal Kenya: an equity analysis
    Jane Chuma
    Kenya Medical Research Institute, Kilifi, Kenya
    Trop Med Int Health 12:673-86. 2007
    ..suggest the need for greater governmental and non-governmental efforts towards protecting the poor from catastrophic illness cost burdens...
  84. ncbi Increasing survival with HIV: impact on nursing care
    James Halloran
    Department of Veterans Affairs, Public Health Strategic Healthcare Group, Center for Quality Management in Public Health, San Antonio, USA
    AACN Clin Issues 17:8-17. 2006
    ..therapy (HAART) has transformed human immunodeficiency virus (HIV) infection from a rapidly progressive catastrophic illness to a chronic condition...
  85. ncbi Caring for the chronically critically ill patient: establishing a wound- healing program in a respiratory care unit
    Miriam Carasa
    Respiratory Care Unit, Mount Sinai Hospital, One Gustave Levy Place, New York, New York 10029, USA
    Am J Surg 188:18-21. 2004
    Chronically critically ill patients may recover from their acute catastrophic illness but still require intensive nursing care...
  86. ncbi Acute aortic dissection
    Desikan Kamalakannan
    St John Hospital and Medical Center, Detroit, MI 48236, USA
    Crit Care Clin 23:779-800, vi. 2007
    Acute aortic dissection is an uncommon but potentially catastrophic illness with high mortality...
  87. ncbi Heart rate characteristics monitoring for neonatal sepsis
    J Randall Moorman
    Department of Medicine, University of Virginia, Charlottesville 22908, USA
    IEEE Trans Biomed Eng 53:126-32. 2006
    ..A predictive algorithm, developed at one center and validated at another, has led to diagnosis and treatment of this subacute and potentially catastrophic illness prior to appearance of symptoms of severe illness.
  88. ncbi Post-ICU mechanical ventilation at 23 long-term care hospitals: a multicenter outcomes study
    David J Scheinhorn
    Barlow Respiratory Hospital and Research Center, 2000 Stadium Way, Los Angeles, CA 90026, USA
    Chest 131:85-93. 2007
    ....
  89. ncbi Antecedents of euthanasia and suicide among older women
    Lori A Roscoe
    Department of Internal Medicine, College of Medicine, University of South Florida, MDC 19, 12901 Bruce B Downs Blvd, Tampa, FL 33612 4799, USA
    J Am Med Womens Assoc 58:44-8. 2003
    ..To identify the characteristics of older women who sought Jack Kevorkian's assistance in dying and to compare them with those of an age-matched sample who committed suicide...
  90. ncbi Hemorrhagic shock and encephalopathy syndrome: neurologic features
    E Ince
    Ankara University Faculty of Medicine, Department of Paediatric, Turkey
    Pediatr Emerg Care 16:260-4. 2000
    ..In this report, we describe four patients of HSES and review the initial and follow-up neurological features, electroencephalography findings, and the results of neuroradiological examinations of this catastrophic illness.
  91. ncbi Coping with health-care costs: implications for the measurement of catastrophic expenditures and poverty
    Gabriela Flores
    Department of Econometrics, University of Geneva, Switzerland
    Health Econ 17:1393-412. 2008
    ..Ignoring health payments leads to underestimate poverty by 7-8% points among hospitalized households; 80% of this adjustment is hidden poverty due to coping...
  92. ncbi President Reagan's legacy
    Robert J Rubin
    Georgetown University, 7901 Springer Road, Bethesda, MD 20817, USA
    J Med Pract Manage 20:5-6. 2004
  93. ncbi Use of health care services and costs of psychiatric disorders among National Health Insurance enrollees in Taiwan
    I Chia Chien
    Institute of Public Health, National Yang Ming University, Taipei, Taiwan
    Psychiatr Serv 55:1427-30. 2004
    ..for enrollees: no psychiatric disorder, a minor psychiatric disorder, a major psychiatric disorder without catastrophic illness registration, and a major psychiatric disorder with catastrophic illness registration (which eliminates ..
  94. doi Catastrophe and caregiving: the failure of medicine as an art
    Arthur Kleinman
    Lancet 371:22-3. 2008
  95. ncbi Hearing bad news
    Janice Morse
    Salt Lake City, UT 84108, USA
    J Med Humanit 32:187-211. 2011
    ..I discuss metaphors used within the languages of hearing bad news. Finally, I discuss implications for a change of focus in the breaking bad news research agenda, that is, from the physician's "performance" to a patient-focused agenda...
  96. ncbi Childhood acute myelomonocytic leukemia (AML-M4) presenting as catastrophic antiphospholipid antibody syndrome
    Angela Orsino
    Division of Rheumatology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 26:327-30. 2004
    ..This unusual presentation of AML has not been previously described in children. Clinical features of antiphospholipid antibody syndrome and current knowledge regarding its association with malignancies are reviewed...
  97. ncbi Facing mortality: exploring the mechanisms of positive growth and the process of recalibration
    Clare Inman
    Department of Psychology, University of Surrey, Guildford, Surrey, UK
    Psychol Health Med 16:366-74. 2011
    ....
  98. ncbi Severely disabled elderly persons with financially catastrophic health care expenses: sources and determinants
    T A Coughlin
    Urban Institute, Washington, DC 20037
    Gerontologist 32:391-403. 1992
    ..For the Channeling sample, out-of-pocket expenses for prescription medicines and for nursing home care were the principle source of catastrophic expenses...
  99. ncbi Nurse life care planning expands role for hospital nurses
    Kelly Lance
    American Association of Nurse Life Care Planners, USA
    Miss RN 69:19. 2007
  100. ncbi Controversies and unresolved issues in antiphospholipid syndrome pathogenesis and management
    William F Baker
    David Geffen School of Medicine, Center for Health Sciences, University of California, Los Angeles, Los Angeles, CA, USA
    Hematol Oncol Clin North Am 22:155-74, viii. 2008
    ..This article summarizes the clinical questions remaining to be answered and debates concerning pathogenesis, diagnosis, and management...
  101. ncbi Descending thoracic aortic aneurysm rupture during postpartum period
    Francis N P Monteiro
    Department of Forensic Medicine and Toxicology, A J Institute of Medical Sciences Affiliated to Rajiv Gandhi University of Health Sciences, Mangalore, India
    J Forensic Sci 56:1054-7. 2011
    ..Descending thoracic aortic aneurysm leading to dissection and spontaneous rupture is a potentially catastrophic illness. Although rare, dissection and rupture of a preexisting aortic aneurysm have been reported during pregnancy ..

Research Grants24

  1. Heat shock proteins in brain ischemia and stroke
    Midori A Yenari; Fiscal Year: 2013
    ..of the blood brain barrier (BBB) leading to brain edema and hemorrhage which can complicate an already catastrophic illness. Recent work in the field has implicated matrix metalloproteinases (MMPs), a family of Zn-dependent ..
  2. Training of the Pediatric Emergency Physician-Scientist
    David M Jaffe; Fiscal Year: 2013
    ..medicine, including high-priority patient-oriented research with emphasis on the relationship between catastrophic illness, emergency care and long-term disabilities...
  3. Training Grant in Bacterial Pathogenesis
    GERALD IRWIN BYRNE; Fiscal Year: 2013
    ..Jude Children's Research Hospital (SJCRH), an internationally known pediatric catastrophic illness hospital...
  4. LIVING WILLS: FOR PRIMARY CARE, AIDS AND CANCER PATIENTS
    JOHN STOECKLE; Fiscal Year: 1990
    ..The study is expected to provide some models for how physicians and patients can handle the process of indicating preferences for care in case of catastrophic illness, and a model living will format.
  5. MORTALITY AND MORBIDITY IN HEMODIALYSIS
    Robert Toto; Fiscal Year: 2001
    End-stage renal disease is a catastrophic illness. Recent reports indicate that the incidence of this disorder is increasing at an alarming rate...
  6. SLEEP, FATIGUE, AND DEXAMETHOSONE IN CHILDHOOD CANCER
    Pamela Hinds; Fiscal Year: 2003
    ..Our study findings will explicate the relationship between sleep efficiency and fatigue, and between sleep, fatigue, and systemic exposure to dexamethasone. ..
  7. GENDER, COPING AND THE ARTHRITIS PAIN EXPERIENCE
    Francis Keefe; Fiscal Year: 2002
    ..This study will examine the nociceptive flexion reflex at rest and during a distraction task designed to manipulate attentional focus. ..
  8. Impact of Neonatal Heart Rate Characteristics Monitoring
    JOSEPH MOORMAN; Fiscal Year: 2009
    ..We feel that there is no more important problem in clinical neonatology, and that this approach represents a truly novel method to assist clinical neonatologists in early diagnosis of sepsis. ..
  9. Heart Rate Characteristics Monitoring in Newborn Infant
    JOSEPH MOORMAN; Fiscal Year: 2008
    ..We feel that HRC monitoring in the NICU is a truly novel approach, and we intend to lead the field in developing predictive algorithms for clinical use in the early diagnosis of neonatal sepsis. ..
  10. Caregiver Coping Skills training for Lung Cancer
    Francis Keefe; Fiscal Year: 2006
    ..The proposed study rigorously evaluations methods for enhancing the effects of caregiver-assisted coping skills training in cancer patients and their caregivers. ..
  11. Exploratory Center for Behavioral Epidemiology (RMI)
    Paul Gertler; Fiscal Year: 2006
    ..We will also explore strategies for expanding this new approach into a more formalized and enduring discipline by developing a sustainable market for its production and consumption. [unreadable] [unreadable]..
  12. Valid Consent/Refusal: A Core Competency for Research
    Susan Goold; Fiscal Year: 2006
    ..Replication of the SPI is also easily accomplished at the many universities in the U.S. and Canada that have SPI programs, and we will disseminate evaluation findings in scholarly publications. [unreadable] [unreadable] [unreadable]..
  13. Self System Therapy and Chronic Low Back Pain
    Francis Keefe; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  14. SPOUSE GUIDED PAIN MANAGEMENT TRAINING FOR CANCER PAIN
    Francis Keefe; Fiscal Year: 2002
    ..This study may lead to major advances in our understanding of cancer pain that occurs at end-of-life and enlarge our repertoire of methods for effectively treating this pain. ..
  15. Regulation of phospholemman by phosphorylation
    JOSEPH MOORMAN; Fiscal Year: 2003
    ..In addition, new knowledge on cell signaling through protein kinases will be generated. ..
  16. An Experiment in Poverty Reduction and Child Development
    Paul Gertler; Fiscal Year: 2004
    ..Could the same results have been achieved through just cash transfers with the requirements for care and monitoring, but without the nutrition supplements? ..
  17. ANXIETY, DEPRESSION, AND NONCARDIAC CHEST PAIN
    Francis Keefe; Fiscal Year: 2005
    ..This study may lead to major advances in our understanding of non-cardiac chest pain and enlarge our repertoire of methods for effectively treating non-cardiac chest pain. ..
  18. Managing Uncertainty in Childhood Cancer Survirorship
    Sheila Santacroce; Fiscal Year: 2005
    ..abstract_text> ..
  19. Coping Skills Training for Early Rheumatoid Arthritis
    Francis Keefe; Fiscal Year: 2005
    ..Finally, future studies could examine whether comprehensive CST alters the immune responses of RA patients to daily stressors. ..
  20. Monitoring Fidelity to Promote Research Integrity
    Sheila Santacroce; Fiscal Year: 2005
    ..The results of the proposed study will be used to inform use of the adapted YACS to promote research integrity in the future development of nursing interventions to improve outcomes for people with chronic health conditions. ..
  21. Patient-Provider Relationship and Diabetes Self-Care
    Paul Ciechanowski; Fiscal Year: 2006
    ..This K-23 award will provide crucial support for the applicant's ongoing development as an investigator, clinician, and educator in the area of diabetes care. ..
  22. Moffitt Aging and Cancer Program Development
    Paul Jacobsen; Fiscal Year: 2007
    ..abstract_text> ..
  23. Poverty Health and Adolescent Risk Behavior
    Paul Gertler; Fiscal Year: 2007
    ..Our research will be guided by the theoretical model of behavioral economics. ..