prolapse

Summary

Summary: The protrusion of an organ or part of an organ into a natural or artificial orifice.

Top Publications

  1. ncbi Sexual function and pelvic floor disorders
    Chahin Achtari
    Urogynaecology Department, Mercy Hospital for Women, East Melbourne, VIC 3002, Australia
    Best Pract Res Clin Obstet Gynaecol 19:993-1008; quiz A1-8. 2005
  2. ncbi Safety and effectiveness of Colpexin Sphere in the treatment of pelvic organ prolapse
    James Chivian Lukban
    Urogynecology Associates of Colorado, Denver, CO, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:449-54. 2006
  3. ncbi The Colpexin Sphere: a new conservative management option for pelvic organ prolapse
    Karen M Sasso
    Evanston Continence Center, Evanston Northwestern Healthcare, Urogynecology, Evanston, IL, USA
    Urol Nurs 26:433-40; quiz 441. 2006
  4. pmc Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina
    Peter G Drewes
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9032, USA
    Am J Pathol 170:578-89. 2007
  5. ncbi Pelvic organ prolapse
    J Eric Jelovsek
    Department of Obstetrics and Gynecology A81, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Lancet 369:1027-38. 2007
  6. ncbi Fallopian tube prolapse after total laparoscopic hysterectomy
    Aileen Caceres
    Division of Gynecological Surgery, Center for Pelvic Health, Florida Hospital at Celebration Health, Celebration, FL 34747, USA
    Obstet Gynecol 112:494-5. 2008
  7. ncbi Optical coherence tomography assessment of the acute effects of stent implantation on the vessel wall: a systematic quantitative approach
    N Gonzalo
    Thoraxcenter, Erasmus MC, 3015 CE Rotterdam, The Netherlands
    Heart 95:1913-9. 2009
  8. ncbi Fallopian tube prolapse
    S Uqaili
    Neath and Port Talbot General Hospital, Baglan, Wales
    J Obstet Gynaecol 26:176-7. 2006
  9. ncbi Fallopian tube prolapse mimicking aggressive angiomyxoma
    Heike Varnholt
    Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA
    Int J Gynecol Pathol 24:292-4. 2005
  10. doi Ascending peritonitis associated with Fallopian tube prolapse following hysterectomy
    R Fox
    Division of Women s and Children s Health, Taunton and Somerset Hospital, Taunton, UK
    J Obstet Gynaecol 28:456. 2008

Detail Information

Publications246 found, 100 shown here

  1. ncbi Sexual function and pelvic floor disorders
    Chahin Achtari
    Urogynaecology Department, Mercy Hospital for Women, East Melbourne, VIC 3002, Australia
    Best Pract Res Clin Obstet Gynaecol 19:993-1008; quiz A1-8. 2005
    ..is common and increases with age and pelvic floor disorders such as urinary incontinence and pelvic organ prolapse. Surgical treatment of pelvic floor disorders has been poorly studied but has the potential to improve sexual ..
  2. ncbi Safety and effectiveness of Colpexin Sphere in the treatment of pelvic organ prolapse
    James Chivian Lukban
    Urogynecology Associates of Colorado, Denver, CO, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:449-54. 2006
    Our objective was to determine the safety and effectiveness of Colpexin Sphere in women with advanced genital prolapse. A total of 39 subjects were enrolled in our prospective multicenter clinical trial, and 27 completed the full 16-week ..
  3. ncbi The Colpexin Sphere: a new conservative management option for pelvic organ prolapse
    Karen M Sasso
    Evanston Continence Center, Evanston Northwestern Healthcare, Urogynecology, Evanston, IL, USA
    Urol Nurs 26:433-40; quiz 441. 2006
    Pelvic organ prolapse is a frequently overlooked condition occurring commonly among women of all ages. A brief overview of pelvic organ prolapse and a discussion of the Colpexin Sphere is provided...
  4. pmc Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina
    Peter G Drewes
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9032, USA
    Am J Pathol 170:578-89. 2007
    Pelvic organ prolapse is strongly associated with a history of vaginal delivery. The mechanisms by which pregnancy and parturition lead to failure of pelvic organ support, however, are not known...
  5. ncbi Pelvic organ prolapse
    J Eric Jelovsek
    Department of Obstetrics and Gynecology A81, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Lancet 369:1027-38. 2007
    Pelvic organ prolapse is downward descent of female pelvic organs, including the bladder, uterus or post-hysterectomy vaginal cuff, and the small or large bowel, resulting in protrusion of the vagina, uterus, or both...
  6. ncbi Fallopian tube prolapse after total laparoscopic hysterectomy
    Aileen Caceres
    Division of Gynecological Surgery, Center for Pelvic Health, Florida Hospital at Celebration Health, Celebration, FL 34747, USA
    Obstet Gynecol 112:494-5. 2008
    Fallopian tube prolapse is an uncommon but reported complication after laparoscopic hysterectomy.
  7. ncbi Optical coherence tomography assessment of the acute effects of stent implantation on the vessel wall: a systematic quantitative approach
    N Gonzalo
    Thoraxcenter, Erasmus MC, 3015 CE Rotterdam, The Netherlands
    Heart 95:1913-9. 2009
    ....
  8. ncbi Fallopian tube prolapse
    S Uqaili
    Neath and Port Talbot General Hospital, Baglan, Wales
    J Obstet Gynaecol 26:176-7. 2006
  9. ncbi Fallopian tube prolapse mimicking aggressive angiomyxoma
    Heike Varnholt
    Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA
    Int J Gynecol Pathol 24:292-4. 2005
    ..Laparotomy did not confirm the clinical suspicion of bowel prolapse and led to resection of the mass...
  10. doi Ascending peritonitis associated with Fallopian tube prolapse following hysterectomy
    R Fox
    Division of Women s and Children s Health, Taunton and Somerset Hospital, Taunton, UK
    J Obstet Gynaecol 28:456. 2008
  11. ncbi [Pyosalpingitis after interadnexal laparoscopic hysterectomy. Two cases]
    Y Lenglet
    Service de gynécologie obstétrique et reproduction humaine, Polyclinique, CHU Hotel Dieu, 11, Boulevard Leon Malfreyt, 63058 Clermont Ferrand cedex 01, France
    Gynecol Obstet Fertil 33:768-71. 2005
    The prolapse of a uterine tube is a rare event after hysterectomy with adnexal conservation. It is described in the literature after abdominal or vagina hysterectomy...
  12. ncbi Posterior prolapse: an important entity even in the modern age of the pars flaccida approach to lap-band placement
    Danny A Sherwinter
    Department of Surgery, Laparoscopy Center, Syosset Hospital, North Shore Long Island Jewish Health System, Syosset, NY 11791, USA
    Obes Surg 16:1312-7. 2006
    ..in patients who undergo laparoscopic adjustable gastric band (LAGB) surgery are pouch dilatation and gastric prolapse (slippage). Gastric prolapse can be divided into the anterior and posterior variety...
  13. ncbi Prolapsed fallopian tube with squamous metaplasia
    K D Jashnani
    J Postgrad Med 48:241-2. 2002
  14. ncbi Fallopian tube prolapse misdiagnosed as vault granulation tissue: a report of three cases
    Young Soo Song
    Department of Pathology, College of Medicine, Hanyang University, 17, Haengdang dong, Sungdong Ku, 133 791 Seoul, Korea
    Pathol Res Pract 201:819-22. 2005
    b>Prolapse of the fallopian tube into the vagina is an uncommon complication caused by either vaginal or abdominal hysterectomy. Recently, however, we encountered three cases with prolapse of the fallopian tube after abdominal hysterectomy...
  15. ncbi Fallopian tube prolapse presenting as a peritoneovaginal fistula
    Michael S Ingber
    Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Can J Urol 17:5117-9. 2010
    ..Likewise, fallopian tube prolapse is an uncommon but known complication of hysterectomy...
  16. ncbi Abdominal sacral colpopexy for repair of neovaginal prolapse in male-to-female transsexuals
    Robert W Frederick
    Tower Urology Institute for Continence, Los Angeles, California 90048, USA
    Urology 64:580-1. 2004
    ..The incidence of neovaginal prolapse is not known but is believed to be relatively rare...
  17. ncbi Fallopian tube prolapse after laparoscopic resection of pelvic endometriosis
    David M Rosenthal
    Department of Obstetrics and Gynecology, North York General Hospital, Toronto, Ontario, Canada
    Obstet Gynecol 105:808-9. 2005
    Fallopian tube prolapse is an unusual but often reported complication after hysterectomy. This problem has not yet been reported in a patient undergoing laparoscopy but not hysterectomy.
  18. ncbi Size of the urogenital hiatus in the levator ani muscles in normal women and women with pelvic organ prolapse
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor 48109 0216, USA
    Obstet Gynecol 91:364-8. 1998
    Compare urogenital hiatus size in normal women and women with pelvic organ prolapse.
  19. ncbi Management of intraoperative iris prolapse: stepwise practical approach
    Naing L Tint
    Cornea and External Eye Diseases, Moorfields Eye Hospital, London, United Kingdom
    J Cataract Refract Surg 38:1845-52. 2012
    Iris prolapse is not an uncommon occurrence during cataract surgery...
  20. ncbi Post-hysterectomy fallopian tube prolapse--a diagnostic pitfall
    D Basu
    Department of Gynaecology, King s Mill Hospital, Sutton in Ashfield, UK
    J Obstet Gynaecol 27:324. 2007
  21. ncbi Fallopian tube prolapse following hysterectomy
    Qing bo Fan
    Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730
    Chin Med Sci J 21:20-3. 2006
    To investigate the clinical diagnosis, treatment, and prevention of fallopian tube prolapse (FTP) after hysterectomy.
  22. ncbi Risk factors and infant outcomes associated with umbilical cord prolapse
    D Uygur
    Zubeyde Hanim Maternity Hospital, Telsizler, Ankara, Turkey
    Int J Gynaecol Obstet 78:127-30. 2002
    Our goal was to identify risk factors associated with umbilical cord prolapse and to review the perinatal outcome of cases of cord prolapse.
  23. ncbi Prolapse of the fallopian tube after hysterectomy associated with exuberant angiomyofibroblastic stroma response: a diagnostic pitfall
    M Michal
    Sikl s Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic
    Virchows Arch 437:436-9. 2000
    We report two cases of prolapse of the fallopian tube associated with an exuberant angiomyofibroblastic stroma response, which occurred after hysterectomy and which is a hitherto unreported feature of this lesion...
  24. ncbi Post-hysterectomy fallopian tube prolapse
    J M Piacenza
    Department of Gynaecology and Obstetrics, University Hospital, Rue Micheli du Crest 25, 1211 Geneva 14, Switzerland
    Eur J Obstet Gynecol Reprod Biol 98:253-5. 2001
    Post-hysterectomy fallopian tube prolapse is a rare complication with only 80 cases described since 1902. Symptoms are non-specific and often of delayed onset...
  25. ncbi Fibroepithelial polyp of distal ureter with periodic prolapse into bladder
    Dimitrios Baltogiannis
    Department of Urology, Ioannina University School of Medicine, Ioannina, Greece
    Urol Int 80:338-40. 2008
    ..Cystoscopy revealed that movement of the polyp was moving forward and backward in the right ureteric orifice. Cold-cut biopsy established the diagnosis. The patient underwent ureteroscopic excision and remains asymptomatic a year later...
  26. ncbi Serious unconventional complications of surgery with stapler for haemorrhoidal prolapse and obstructed defaecation because of rectocoele and rectal intussusception
    G Naldini
    Department of General Surgery IV, Santa Chiara Hospital, Pisa, Italy
    Colorectal Dis 13:323-7. 2011
    Treatment of haemorrhoidal prolapse by stapled haemorrhoidopexy (SH) and obstructed defaecation syndrome with the stapled transanal rectal resection (STARR) technique is becoming increasingly popular with patients and surgeons...
  27. ncbi Gastric hyperplastic polyps: a heterogeneous clinicopathologic group including a distinct subset best categorized as mucosal prolapse polyp
    Elvira Gonzalez-Obeso
    Department, Hospital General de Ciudad Real, Ciudad Real, Spain
    Am J Surg Pathol 35:670-7. 2011
    ..Gastric hyperplastic polyps are the second most common subtype of gastric polyps. There has been an ongoing debate about their precise diagnostic criteria and etiological associations...
  28. ncbi Cloaca prolapse and cystitis in green iguana (Iguana iguana) caused by a novel Cryptosporidium species
    Marja J L Kik
    Department of Pathobiology, Pathology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands
    Vet Parasitol 175:165-7. 2011
    ..Based on the small subunit ribosomal RNA gene the cryptosporidia were characterized as belonging to the intestinal cryptosporidial lineage, but not to Cryptosporidium saurophilum or Cryptosporidium serpentis species...
  29. ncbi Surgical management of tubal prolapse
    W A A Tjalma
    Department of Gynecology and Gynecological Oncology, University Hospital of Antwerp, Edegem, Belgium
    Int J Gynaecol Obstet 83:207-8. 2003
  30. ncbi Vitreous prolapse through the scleral wound in 25-gauge transconjunctival vitrectomy
    H Shimada
    Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan
    Eur J Ophthalmol 18:659-62. 2008
    To examine the effectiveness of excising peripheral vitreous until the cannula tip is exposed to prevent vitreous prolapse through the scleral wound in 25-gauge transconjunctival vitrectomy.
  31. ncbi Pyloric obstruction caused by prolapse of a hyperplastic gastric polyp
    Herwig Cerwenka
    Department of Visceral Surgery, Karl Franzens University, Graz, Austria
    Hepatogastroenterology 49:958-60. 2002
    ..Histologic examination showed a hyperplastic polyp without dysplasia or malignancy. The significance of gastric polyps is discussed from the clinical point of view...
  32. ncbi Fascial and muscular abnormalities in women with urethral hypermobility and anterior vaginal wall prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, 48109 0276, USA
    Am J Obstet Gynecol 187:93-8. 2002
    ..Our purpose was to assess the structural integrity of individual elements of the urethral and anterior vaginal wall support system...
  33. ncbi A prospective study of laparoscopic sacrocolpopexy for the management of pelvic organ prolapse
    C E North
    Department of Urogynaecology, St Mary s Hospital, Whitworth Park, Manchester, UK
    BJOG 116:1251-7. 2009
    ..Assessment of the 2-year outcome of laparoscopic sacrocolpopexy...
  34. ncbi Umbilical cord prolapse
    Monique G Lin
    Center for Research in Women s Health, Division of Maternal Fetal Medicine, Department of Obstetrics Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7333, USA
    Obstet Gynecol Surv 61:269-77. 2006
    b>Prolapse of the umbilical cord is a rare obstetric emergency that in the viable fetus necessitates an expeditious delivery...
  35. ncbi Local treatment of a loop colostomy prolapse with a linear stapler
    K Tepetes
    Department of Surgery, University Hospital of Larissa, Larissa 41110, Greece
    Tech Coloproctol 9:156-8. 2005
    Stomal prolapse is considered to be a common complication especially following loop colostomies...
  36. ncbi Retrospective multicentre study of the new minimally invasive mesh repair devices for pelvic organ prolapse
    M Abdel-Fattah
    Urogynaecology Unit, Southern General Hospital, Greater Glasgow and Clyde Health Board, Glasgow, UK
    BJOG 115:22-30. 2008
    To assess the complications and short-term outcomes of prolapse repair mesh devices used in the management of female pelvic organ prolapse (POP).
  37. ncbi Florid vascular proliferation of the colon related to intussusception and mucosal prolapse: potential diagnostic confusion with angiosarcoma
    N R Bavikatty
    Department of Pathology, University of Michigan Hospitals, 1500 E. Medical Center Dr, Ann Arbor, MI 48109-0054, USA
    Mod Pathol 14:1114-8. 2001
    ..The overlying mucosa showed ulceration with ischemic-type changes, and had features of mucosal prolapse. A possible underlying arteriovenous malformation was identified in two cases...
  38. ncbi Incidence and patient characteristics of vaginal cuff dehiscence after different modes of hysterectomies
    Hye Chun Hur
    Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Minim Invasive Gynecol 14:311-7. 2007
    ....
  39. ncbi What causes eyelid bags? Analysis of 114 consecutive patients
    Robert Alan Goldberg
    Division of Orbital and Ophthalmic Plastic Surgery, Jules Stein Eye Institute, and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90095 7006, USA
    Plast Reconstr Surg 115:1395-402; discussion 1403-4. 2005
    ..The purpose of this study was to identify the anatomical basis for perception of lower eyelid bags in patients seeking aesthetic surgery and to evaluate the cumulative contribution of different anatomic characteristics before surgery...
  40. ncbi Surgical management of anterior vaginal wall prolapse: an evidencebased literature review
    Christopher Maher
    Royal Women s, Mater and Wesley Hospitals, Level 4 Suite 86 Sandford Jackson Building, 30 Chasely Street Auchenflower, 4066, QLD, Brisbane, Australia
    Int Urogynecol J Pelvic Floor Dysfunct 17:195-201. 2006
    The aim of this review is to summarize the available literature on surgical management of anterior vaginal wall prolapse. A Medline search from 1966 to 2004 and a hand-search of conference proceedings of the International Continence ..
  41. ncbi Posthysterectomy intestinal prolapse after coitus and vaginal repair
    Kunter Yuce
    Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
    Arch Gynecol Obstet 272:80-1. 2005
    ..Furthermore, vaginal cuff rupture with the prolapse of the small bowel through the vagina during sexual intercourse after abdominal hysterectomy in a premenopausal ..
  42. ncbi Familial transmission of genitovaginal prolapse
    Gregory S Jack
    Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:498-501. 2006
    Some females with little to no risk factors develop prolapse, while other females with multiple risk factors do not. It appears that some women may have a predisposition for prolapse in the setting of equivalent risk factors...
  43. ncbi Epidemiology of pelvic organ prolapse in rural Gambia, West Africa
    Caroline Scherf
    Department of Obstetrics and Gynaecology, University of Wales College of Medicine, Cardiff, UK
    BJOG 109:431-6. 2002
    To investigate the prevalence of pelvic organ prolapse in rural Gambia.
  44. ncbi Prolapsed hyperplastic gastric polyp causing pancreatitis: case report
    R A De La Cruz
    Department of Radiology, , , Madrid, Spain
    Abdom Imaging 26:584-6. 2001
    ..The compression and obstruction of the ampulla of Vater by this polyp caused acute pancreatitis. An overview of imaging findings, general considerations about hyperplastic gastric polyps, and a review of the literature are provided...
  45. pmc Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis
    M Jansen
    Academic Medical Centre of the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Gut 55:1-5. 2006
    ..We postulate that a genetic predisposition to epithelial prolapse underlies the formation of the polyps associated with PJS...
  46. ncbi The history and evolution of pessaries for pelvic organ prolapse
    Sheetle M Shah
    Department of Obstetrics and Gynaecology, Mayday University Hospital, 530 London Road, CR7 7YE, Croydon, U K
    Int Urogynecol J Pelvic Floor Dysfunct 17:170-5. 2006
    The use of pessaries for the treatment of genital prolapse dates back prior to the days of Hippocrates and their use has been documented in early Egyptian papyruses...
  47. ncbi [Surgical management of pelvic organ prolapse in women: laparoscopic or vaginal sacrocolpopexy?]
    G Descargues
    Centre de pelvipérinéologie, Clinique Saint Hilaire, 2, place Saint Hilaire, 76000 Rouen, France
    Gynecol Obstet Fertil 36:978-83. 2008
    To compare the safety and the efficacy of the laparoscopic and vaginal technique for the surgical management of pelvic organ prolapse, with systematic support of the three compartments and prosthetic reinforcements.
  48. ncbi Pessary use in advanced pelvic organ prolapse
    Kenneth Powers
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology and Women s Health, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, NY 10467, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:160-4. 2006
    The objective of this study was to review our experience with pessary use for advanced pelvic organ prolapse. Charts of patients treated for Stage III and IV prolapse were reviewed...
  49. ncbi Gastric slippage as an emergency: diagnosis and management
    Al Waleed M Abuzeid
    Royal Free and University College Medical School Department of Surgery, Whittington Campus, Highgate Hill, London, UK
    Obes Surg 17:559-61. 2007
    ..The most prevalent complication following LAGB is band slippage leading to gastric prolapse. These cases often present to the emergency department where surgeons need to appropriately diagnose and ..
  50. ncbi Levator defects are associated with prolapse after pelvic floor surgery
    Angela N Model
    Nepean Clinical School, University of Sydney, Penrith, NSW, Australia
    Eur J Obstet Gynecol Reprod Biol 153:220-3. 2010
    Pelvic organ prolapse recurrence after pelvic floor surgery is a common problem. This study was designed to assess whether avulsion defects of the puborectalis muscle are associated with recurrent pelvic organ prolapse and its symptoms.
  51. ncbi The role of laparoscopic surgery in the management of tubal prolapse: a 7 case series and literature review
    Keith W K Lo
    Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
    Surg Innov 14:24-6. 2007
    Fallopian tube prolapse is an unusual complication after hysterectomy. Different surgical options have been proposed, including abdominal, vaginal, and combined laparoscopic approaches, with partial or complete salpingectomy...
  52. ncbi Lacrimal gland prolapse in blepharochalasis
    K S Hundal
    Eye (Lond) 18:429-30. 2004
  53. ncbi Prolapse of aortic intimal flap into the left ventricle: a rare cause of global myocardial ischemia in acute type A aortic dissection
    Yoichi Sato
    Department of Cardiovascular Surgery, Fukushima Medical University School of Medicine1 Hikarogaoka, Fukushima 960 1295, Japan
    Circ J 70:214-5. 2006
    ..Acute aortic dissection must be kept in mind when presented with myocardial ischemia and TEE is the most useful method for detecting a prolapsing cylindrical intimal flap...
  54. ncbi Reducing band slippage in laparoscopic adjustable gastric banding: the mesh plication pars flaccida technique
    Chantel Mary Thornton
    Department of Surgery, Royal Hobart Hospital, Tasmania, Australia
    Obes Surg 19:1702-6. 2009
    ..This involves prolapse of part of the stomach, with varying degrees of gastric obstruction...
  55. ncbi Management of the urethral outlet in patients with severe prolapse
    Lauri J Romanzi
    Obstetrics and Gynecology, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, New York, USA
    Curr Opin Urol 12:339-44. 2002
    ..of women seeking consultation for pelvic floor disorders, a large portion of which will involve pelvic organ prolapse (POP) and lower urinary tract dysfunction, are expected to reach epidemic proportions within the next decade...
  56. ncbi Umbilical cord prolapse--a review of diagnosis to delivery interval on perinatal and maternal outcome
    Rozilla S Khan
    Department of Obstetrics and Gynaecology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 57:487-91. 2007
    To determine the significance of the Diagnosis to Delivery Interval (DDI) on perinatal outcome and maternal complications in patients with umbilical cord prolapse.
  57. ncbi Full-thickness pouch prolapse after restorative proctocolectomy: a potential future problem treated by the new technique of external pelvic neorectal suspension (the Express procedure)
    Norman S Williams
    Centre for Academic Surgery, The Royal London Hospital, Whitechapel, London, United Kingdom
    Dis Colon Rectum 47:1415-9. 2004
    Full thickness pouch prolapse following restroative proctocolectomy is an uncommon complication but likely to become more frequent as this population of patients grows older...
  58. ncbi [Diagnosis of uterovaginal prolapse]
    M E Vierhout
    Universitair Medisch Centrum St Radboud, afd Obstetrie en Gynaecologie, Huispost 415, 6500 HB Nijmegen
    Ned Tijdschr Geneeskd 148:2432-6. 2004
    Uterovaginal prolapse is a frequently occurring problem, being encountered in 2-88 per 1000 women in the population. When diagnosing uterovaginal prolapse, both the anatomical abnormality and the severity should be indicated...
  59. ncbi Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence
    Paulo C R Palma
    Division of Urology, Campinas State University Unicamp, Sao Paulo, Brazil
    Int Urogynecol J Pelvic Floor Dysfunct 17:670-1. 2006
    ..The authors present a case report of a granulomatous reaction leading to urethral prolapse, 3 months after the transurethral injection of calcium hydroxylapatite...
  60. ncbi Is prolapse gastropathy a cause of upper gastrointestinal bleeding?
    Gazi Yoruk
    Department of Gastroenterology, Ataturk Teaching and Research Hospital, Izmir, Turkey
    Turk J Gastroenterol 14:106-10. 2003
    b>Prolapse gastropathy is a clinical syndrome involving the invagination of a part of the gastric mucosa into the lower esophagus resulting in well demarcated hemorrhagic mucosa and sometimes bleeding...
  61. ncbi Complete eversion and prolapse of bladder concurrent with primary adenocarcinoma
    Y H Kim
    Department of Radiology, Korea University, College of Medicine, Anam Hospital, 126 1, 5 ka Anam dong, Sungbuk Ku, Seoul 136 705, Korea
    Br J Radiol 79:e8-11. 2006
    Complete eversion and prolapse of the urinary bladder is extremely rare. To the best of our knowledge, the imaging findings of complete bladder eversion have not been documented in the literature...
  62. ncbi Role of perineal ultrasound in the evaluation of urinary stress incontinence and pelvic organ prolapse: a systematic review
    Orietta Dalpiaz
    Department of Urology, University of Verona, Italy
    Neurourol Urodyn 25:301-6; discussion 307. 2006
    ....
  63. ncbi Prevalence and management of prolapse of the ileoanal pouch
    Mitra Ehsan
    Overlake Colon and Rectal Clinic, Bellevue, Washington, USA
    Dis Colon Rectum 47:885-8. 2004
    ..These may jeopardize the pouch and may require pouch salvage procedures. Prolapse of the ileoanal pouch is a little-known complication infrequently noted in the literature...
  64. ncbi Giant left atrium, giant thrombus, and left atrial prolapse in a patient with mitral valve replacement
    Ilyas Akdemir
    Department of Cardiology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
    Echocardiography 19:691-2. 2002
  65. ncbi Pelvic-floor muscle function in women with pelvic organ prolapse
    Diane F Borello-France
    Department of Physical Therapy, 111 Health Sciences Bldg, Duquesne University, Pittsburgh, PA 15282, USA
    Phys Ther 87:399-407. 2007
    The purpose of this study was to determine whether pelvic organ prolapse severity, pelvic symptoms, quality of life, and sexual function differ based on pelvic-floor muscle function in women planning to have prolapse surgery.
  66. ncbi Classification and evaluation of prolapse
    Lone Mouritsen
    Department of Gynecology and Obstetrics, Glostrup Hospital, University of Copenhagen, 2600 Glostrup, Denmark
    Best Pract Res Clin Obstet Gynaecol 19:895-911. 2005
    Pelvic organ prolapse is prevalent among older women. Milder stages of prolapse, cranial to the hymen, are common and usually symptomless. A specific symptom is a bulge outside the vagina...
  67. ncbi Risk factors and perinatal outcomes associated with umbilical cord prolapse
    Berna Dilbaz
    Obstetrics and Gynecology, Ministry of Health, Ankara Etlik Maternity and Women s Health Teaching, Research Hospital, Ankara, Turkey
    Arch Gynecol Obstet 274:104-7. 2006
    To utilize infant outcomes and to identify risk factors associated with umbilical cord prolapse.
  68. ncbi Magnetic resonance imaging measurements of extraocular muscle path shift and posterior eyeball prolapse from the muscle cone in acquired esotropia with high myopia
    Yoshiko Aoki
    Department of Ophthalmology, Shiga University of Medical Science, Otsu, Shiga, Japan
    Am J Ophthalmol 136:482-9. 2003
    To investigate extraocular muscle (EOM) path shift and prolapse of posterior eyeball from muscle cone in acquired esotropia with high myopia (AEHM), using magnetic resonance imaging.
  69. ncbi Primary surgery of genital prolapse: a shift in treatment tradition
    Kristina Crafoord
    Department of Molecular and Clinical Medicine, Division of Obstetrics and Gynecology, Faculty of Health Sciences, Linkoping University, Linköping 58185, Sweden
    Acta Obstet Gynecol Scand 85:1104-8. 2006
    The use of complete repairs in genital prolapse surgery has been questioned because of the possible adverse effects of the surgery on the urogenital and sexual function and selective repairs have been advocated...
  70. ncbi Do overactive bladder symptoms improve after repair of anterior vaginal wall prolapse?
    G Alessandro Digesu
    Urogynaecology Unit, Buzzi Hospital, ICP, Milan, Italy
    Int Urogynecol J Pelvic Floor Dysfunct 18:1439-43. 2007
    This study aims to evaluate the changes of overactive bladder symptoms to anterior vaginal wall prolapse repair...
  71. ncbi Fetal survival after umbilical cord prolapse for more than three days. A case report
    D M Poetker
    Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1080, USA
    J Reprod Med 46:776-8. 2001
    BACKGROUND: Umbilical cord prolapse is an uncommon obstetric emergency. CASE: A 28-year-old woman, gravida 1, para 0, presented at 23 2/7 weeks' gestation with vaginal leakage of fluid. She was diagnosed with umbilical cord prolapse...
  72. ncbi Factors associated with pelvic floor dysfunction with emphasis on urinary and fecal incontinence and genital prolapse: an epidemiological study
    Eva Uustal Fornell
    Department of Molecular and Clinical Medicine, Faculty of Health Sciences, University Hospital, Linkoping, Sweden
    Acta Obstet Gynecol Scand 83:383-9. 2004
    To describe a general population of women with regard to factors associated with urinary and fecal incontinence and genital prolapse symptoms.
  73. ncbi Vitreous prolapse and IOL dislocation during intravitreal injection of triamcinolone acetonide
    Robert F Degenring
    Department of Ophthalmology Cologne Merheim, Cologne Hospitals, Ostmerheimer Str 200, 51109, Cologne, Germany
    Graefes Arch Clin Exp Ophthalmol 244:1043-4. 2006
    ..To report on procedure-related anterior segment complications during intravitreal injections...
  74. ncbi SIS graft for anterior vaginal wall prolapse repair--a case-controlled study
    Charlotte Chaliha
    Urogynaecology Unit, Academic Department of Obstetrics and Gynaecology, Imperial College, St Mary s Hospital, London, UK
    Int Urogynecol J Pelvic Floor Dysfunct 17:492-7. 2006
    The purpose of this study was to assess the effect on quality of life and prolapse severity of traditional anterior repair compared to anterior repair with a small intestine submucosa (SIS) graft...
  75. ncbi Local correction of a transverse loop colostomy prolapse by means of a stapler device
    K Maeda
    Department of Surgery, Fujita Health University, School of Medicine, 1 98 Kutsukake, Toyoake, Aichi, 470 1192, Japan
    Tech Coloproctol 8:45-6. 2004
    b>Prolapse is a common complication in patients with a transverse loop colostomy. In most cases, the prolapse can be managed conservatively awaiting time for closure eventually...
  76. ncbi Analysis of prolapse in cardiovascular stents: a constitutive equation for vascular tissue and finite-element modelling
    P J Prendergast
    Center for Bioengineering, Department of Mechanical Engineering, Trinity College, Dublin 2, Ireland
    J Biomech Eng 125:692-9. 2003
    ..Because of this, the deflection of the tissue between the struts of the stent (called prolapse or "draping") has been used as a measure of the potential of a stent to cause restenosis...
  77. ncbi The development of pelvic organ prolapse following isolated Burch retropubic urethropexy
    Christina H Kwon
    Department of Obstetrics Gynecology, Division of Urogynecology, New York University, 550 First Avenue, NBV9E2, New York, NY 10016, USA
    Int Urogynecol J Pelvic Floor Dysfunct 14:321-5; discussion 325. 2003
    The purpose of our study was to examine the incidence of prolapse in a group of women who had had an isolated Tanagho modification of the Burch colposuspension performed without significant pelvic organ prolapse preoperatively...
  78. ncbi Pathophysiology and prevention of loop stomal prolapse in the transverse colon
    K Maeda
    Department of Surgery, Fujita Health University School of Medicine, 1 98 Kutsukake, Toyoake, 470 1192 Aichi, Japan
    Tech Coloproctol 7:108-11. 2003
    We investigated both pathogenesis and prevention of loop transverse stomal prolapse. Seven patients with reducible prolapsed stoma were studied under fluoroscopy after staining the prolapsed stoma and the colon by barium medium while ..
  79. ncbi Experiences and expectations of women with urogenital prolapse: a quantitative and qualitative exploration
    S Srikrishna
    Department of Urogynaecology, King s College Hospital, London, UK
    BJOG 115:1362-8. 2008
    To explore the expectations and goals of women undergoing surgery for urogenital prolapse using both a quantitative quality of life approach exploring symptom bother and a qualitative interview-based approach exploring patient goals and ..
  80. ncbi Correction of end colostomy prolapse using a curved surgical stapler, performed under sedation
    H J M Ferguson
    City Hospital, Birmingham, B18 7QH, UK
    Tech Coloproctol 14:165-7. 2010
    Acute stoma prolapse most commonly occurs following emergency surgery, frequently in patients with significant medical co-morbidities...
  81. ncbi Cadaveric prolapse repair with sling: intermediate outcomes with 6 months to 5 years of followup
    Robert W Frederick
    Tower Urology Institute for Continence, Los Angeles, California, USA
    J Urol 173:1229-33. 2005
    We present the prospective, intermediate-term results for cadaveric prolapse repair with sling as combined treatment of stress urinary incontinence and cystocele.
  82. ncbi Pregnancy, labor, delivery, and pelvic organ prolapse
    Eddie H M Sze
    Department ofObstetrics and Gynecology, East Carolina University Brody School of Medicine, Pitt County Memorial Hospital, Greenville, North Carolina, USA
    Obstet Gynecol 100:981-6. 2002
    To compare 1) the occurrence of pelvic organ prolapse after vaginal and cesarean delivery, and 2) the susceptibility of black and white women to developing prolapse during childbirth.
  83. ncbi 17beta-estradiol suppresses proliferation of fibroblasts derived from cardinal ligaments in patients with or without pelvic organ prolapse
    Y M Liu
    Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Hum Reprod 21:303-8. 2006
    Estrogen replacement therapy (ERT) has been used in the treatment of pelvic organ prolapse (POP) but clinical results are inconclusive...
  84. ncbi Obstetric management of a woman's first delivery and the implications for pelvic floor surgery in later life
    Ramalingam Uma
    Division of Maternal and Child Health Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    BJOG 112:1043-6. 2005
    ..To determine the influence of intrapartum care during a first delivery on the risk of pelvic floor surgery in later life...
  85. ncbi The use of prosthetics in pelvic reconstructive surgery
    Colin Birch
    Division of Urogynaecology, Department of Obstetrics and Gynecology, Foothills Medical Centre, North Tower, 1441 29th Street, NW Calgary, Alta, Canada T2N 4J8
    Best Pract Res Clin Obstet Gynaecol 19:979-91. 2005
    ..The lifetime risk of undergoing prolapse or incontinence surgery in the USA is 1 in 11...
  86. ncbi Sedation and local anaesthesia for vaginal pelvic floor repair of genital prolapse using mesh
    Folke Flam
    Department of Gynecology, St Goran s Hospital and Sabbatsberg Hospital, 11281 Stockholm, Sweden
    Int Urogynecol J Pelvic Floor Dysfunct 18:1471-5. 2007
    In this study of the surgical repair of pelvic organ prolapse (POP), the vaginal pelvic floor repair with mesh (PFR-Mesh) procedure was used. The procedure is originally named TVM...
  87. ncbi [Imaging pelvic floor prolapse]
    B Deval
    Service de Gynecologie Obstetrique, Université Bichat Beaujon, Hopital Beaujon, 100, Avenue du General Leclerc, 92110 Clichy
    J Gynecol Obstet Biol Reprod (Paris) 32:22-9. 2003
    ..MR imaging (MRI) may be used as an alternative to dynamic cystoproctography for the evaluation of pelvic floor prolapse. Our study aimed to define the range of dynamic pelvic MRI aspects observed during the exploration of pelvic ..
  88. pmc The significance of bladder trabeculation in the female lower urinary system: an objective evaluation by urodynamic studies
    Sang Wook Bai
    Department of Obstetrics and Gynecology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 46:673-8. 2005
    ..to investigate the relationship between bladder trabeculation, urinary function, and the stage of pelvic organ prolapse (POP)...
  89. ncbi Anatomical and functional significance of urogenital hiatus in primary urodynamic stress incontinence
    W C Huang
    Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan, ROC
    Ultrasound Obstet Gynecol 27:71-7. 2006
    ..To explore the correlations of anatomical and functional sonographic parameters of urogenital hiatus in primary urodynamic stress incontinence...
  90. ncbi Dynamic evaluation of female pelvic organ prolapse by extended proctography
    Frederick M Kelvin
    Department of Radiology, Methodist Hospital of Indiana, 1701 North Senate Boulevard, Indianapolis, IN 46202, USA
    Radiol Clin North Am 41:395-407. 2003
    ..Large enteroceles and marked vaginal vault prolapse, in particular, are much more amenable to correction by transabdominal surgery...
  91. ncbi MRI of pelvic floor dysfunction: dynamic true fast imaging with steady-state precession versus HASTE
    Elizabeth M Hecht
    Department of Radiology, New York University Medical Center, 560 First Ave, Ste HW 202, New York, NY 10016, USA
    AJR Am J Roentgenol 191:352-8. 2008
    The objective of our study was to retrospectively compare the degree of pelvic organ prolapse shown on dynamic true fast imaging with steady-state precession (FISP) versus HASTE sequences in symptomatic patients.
  92. ncbi Magnetic resonance imaging in evaluating functional disorders of female pelvic floor
    P Torricelli
    Dipartimento di Scienze Mediche, Oncologiche e Radiologiche, Sezione di Scienze Radiologiche, Universita degli Studi di Modena e Reggio Emilia, Italy
    Radiol Med 103:488-500. 2002
    ..To evaluate the diagnostic capabilities of MRI in the study of functional diseases of the female pelvic floor...
  93. ncbi MRI of pelvic organ prolapse
    Harpreet K Pannu
    The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Eur Radiol 14:1456-64. 2004
  94. ncbi Pelvic floor surgery in the older woman
    Kimberly A Gerten
    Department of Obstetrics and Gynecology, Division of Women s Pelvic Medicine and Reconstructive Surgery, University of Alabama at Birmingham, USA
    Clin Obstet Gynecol 50:826-43. 2007
    Pelvic floor disorders including urinary incontinence, pelvic organ prolapse, and fecal incontinence are common problems encountered by the older woman...
  95. ncbi Practicalities and pitfalls of pessaries in older women
    Elisa Rodriguez Trowbridge
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0276, USA
    Clin Obstet Gynecol 50:709-19. 2007
    ..Although there are some downsides in using pessaries in clinical practice, many of these pitfalls can be appropriately addressed with education and training of clinician and patients...
  96. ncbi Evisceration after enterocele repair: a rare complication of vaginal surgery
    H S Virtanen
    University Central Hospital of Turku, Finland
    Int Urogynecol J Pelvic Floor Dysfunct 7:344-7. 1996
    ..Of the reported repair operations, 57% were performed transabdominably, 28% transvaginally, and 15% via a combined abdominovaginal route. The authors present 1 more case treated transvaginally, with a review of the literature...
  97. ncbi Tension-free obturator tape (Monarc Subfascial Hammock) in patients with or without associated procedures
    Georges Mellier
    Department of Gynecology and Obstetrics, Edouard Herriot Hospital, Lyon, France
    Int Urogynecol J Pelvic Floor Dysfunct 18:165-72. 2007
    ..4% in the Monarc + other surgery group. Pelvic floor defects, benign uterine disorders, and stress urinary incontinence can be safely treated with transobturator tape, using the Monarc device, and concomitant vaginal procedures...
  98. ncbi Ultrasound imaging of the pelvic floor. Part II: three-dimensional or volume imaging
    H P Dietz
    Royal Prince Alfred Hospital, Sydney, Australia
    Ultrasound Obstet Gynecol 23:615-25. 2004
    ..To date, such systems have been used to image the urethra, the levator ani and paravaginal supports, prolapse and implants used in pelvic floor reconstruction and anti-incontinence surgery...
  99. ncbi Transvaginal bowel evisceration following pelvic floor repair
    S Sathiyathasan
    Chase Farm Hospital, Enfield, London, UK
    Arch Gynecol Obstet 277:183-4. 2008
  100. ncbi [Treatment of genito-urinary prolapses by spinuos fixation with a polypropylene prosthesis]
    Philippe Montête
    Service d Urologie, centre hospitalier René Dubos, 6, av enue de l Ile de France, BP 79, 95303 Cergy Pontoise
    Prog Urol 12:517-20; discussion 521. 2002
    ..The very satisfactory results achieved let us think that this technique will take a great place in the treatment of the genito-urinary prolapses...
  101. ncbi Pelvic organ support in nulliparous pregnant and nonpregnant women: a case control study
    Amy L O'Boyle
    Department of Obstetrics and Gynecology, Division of Urogynecology, Madigan Army Medical Center, Tacoma, WA 98431, USA
    Am J Obstet Gynecol 187:99-102. 2002
    ..Our purpose was to compare pelvic organ support in nulliparous pregnant and nonpregnant women at a single institution...

Research Grants66

  1. Stem Cell Homing for Treatment of Female Pelvic Floor Disorders
    Margot S Damaser; Fiscal Year: 2013
    ..female pelvic floor disorders (FPFD): stress urinary incontinence (SUI), fecal incontinence, and pelvic organ prolapse (POP)...
  2. Genetics of Spontaneous Pelvic Organ Prolapse in the Mouse
    Jay E Reeder; Fiscal Year: 2010
    We have discovered a form of inherited and spontaneous pelvic organ prolapse (S-POP) in mice. The mutation appeared in a colony of transgenic mice. The phenotype has been isolated from the transgene in FVB/N mice by selective breeding...
  3. The roles of MKP-1 in Gram-negative bacterial sepsis and colitis
    Yusen Liu; Fiscal Year: 2010
    ..mice housed in conventional but not pathogen-free conditions are known to develop colitis associated with rectal prolapse. Conversely, deletion of both MKP-1 and IL-10 caused severe rectal prolapse even in pathogen-free conditions...
  4. Regulation of Periostin by TGFbeta and BMP in Heart Development
    Thomas Doetschman; Fiscal Year: 2010
    ..g. Marfan's syndrome, Ehlers-Danlos syndrome, floppy mitral valve syndrome and mitral valve prolapse)...
  5. Mid Career Award in Patient Oriented Pelvic Floor Research
    Holly E Richter; Fiscal Year: 2013
    ..in the older woman, rectoceles, defecatory dysfunction, outcomes associated with sphincteroplasty and rectal prolapse surgery...
  6. Pelvic Floor Disorders Network - Duke University Clinical Site
    Anthony G Visco; Fiscal Year: 2013
    ..with expertise in both surgical and non-surgical management of urinary incontinence (Ul), pelvic organ prolapse (POP), fecal incontinence, and defecatory dysfunction...
  7. Pittsburgh Pelvic Floor Research Program
    Halina M Zyczynski; Fiscal Year: 2013
    ..record of successful contribution to multicenter studies of urinary and fecal incontinence, and pelvic organ prolapse. We are particularly well suited to be a clinical site in the PFDN because of our volume, research infrastructure ..
  8. Architectural Design of the Pelvic Floor Skeletal Muscles
    Marianna Alperin; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders (PFD) include pelvic organ prolapse (POP), urinary incontinence, and fecal incontinence...
  9. Genetic Epidemiology of Pelvic Organ Prolapse
    Jennifer Marie Wu; Fiscal Year: 2010
    Pelvic organ prolapse represents a major health issue for women with a prevalence of 40% in postmenopausal women...
  10. NMR studies of the effects of mode of birth on vaginal elastin
    Gregory Boutis; Fiscal Year: 2013
    DESCRIPTION (provided by applicant) The management and treatment of pelvic organ prolapse in the United States currently exceeds one billion dollars in costs annually...
  11. Patient-Reported Outcomes in Functioning for Female Pelvic Floor Disorders
    Vivian W Sung; Fiscal Year: 2013
    ..TOPIC: Female PFDs, including urinary incontinence, pelvic organ prolapse and fecal incontinence, are chronic conditions with a significant impact on multiple aspects of a woman's ..
  12. Elastic Fiber Homeostasis in the Vaginal Wall
    Hiromi Yanagisawa; Fiscal Year: 2013
    ..One of the most prevalent pelvic floor disorders is pelvic organ prolapse, a condition in which the pelvic organs (bladder, vagina, cervix and uterus) herniate through the vaginal opening...
  13. Core-Shell Fiber Mesh for the Treatment of UI and PFD in Elderly Women
    MICHAEL P H LAU; Fiscal Year: 2011
    ..e. bladder neck) in UI or genital organs in genital prolapse. However, difficulty in tensioning commercially available surgical mesh presents a barrier to dialing in optimal ..
  14. Physical Activity and Pelvic Floor Disorders
    Ingrid E Nygaard; Fiscal Year: 2012
    ..impacts pelvic floor disorders is important: half of American women have urinary incontinence or pelvic organ prolapse and one in nine undergoes surgery for these conditions...
  15. Brown/WIH Pelvic Floor Disorders Network Site
    Vivian W Sung; Fiscal Year: 2013
    ..RELEVANCE: Female pelvic floor disorders including urinary incontinence, pelvic organ prolapse and fecal incontinence are common, disabling conditions and are a significant public health issue...
  16. Macrophage Phenotype as a Determinant of Outcome in Pelvic Organ Prolapse Repair
    BRYAN NICKLAUS BROWN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic organ prolapse (POP) results in 225,000-300,000 surgical procedures per annum and with costs exceeding $1 billion in the United States...
  17. Vaginal Tactile Imager for Pelvic Floor Biomechanical Assessment
    Vladimir Egorov; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic organ prolapse is a highly prevalent condition affecting at least 50% of women in the US during their lifetimes...
  18. Cesarean and vaginal birth: cohort study of the impact on pelvic floor disorders
    VICTORIA LYNN HANDA; Fiscal Year: 2013
    ..very high prevalence of female pelvic floor disorders (urinary incontinence, fecal incontinence, and pelvic organ prolapse), the biological mechanisms underlying these disorders are uncertain...
  19. Natural History of Stress, Urge and Mixed Urinary Incontinence in Women
    XIAOWEI SHERRY YAN; Fiscal Year: 2013
    ..Risk factors common to stress and urge UI include obesity, parity, hormone replacement therapy, prolapse and others...
  20. 3T Pelvic MRI Measures After Childbirth: Pre-Pregnancy and 6 Months Postpartum (R
    Holly E Richter; Fiscal Year: 2010
    ..attributable to pregnancy and childbirth and associated with pelvic floor disorders, including incontinence and prolapse through the use of 3T MRI imaging pre-pregnancy and 6 months postpartum...
  21. Pelvic floor Disorders Network-Data Coordinating Center
    CATHERINE A SPINO; Fiscal Year: 2010
    Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States...
  22. Comprehensive Evaluation of Prolapse Meshes by an Interdisciplinary Research Team
    Pamela A Moalli; Fiscal Year: 2013
    Project Summary/Abstract: Comprehensive Evaluation of Prolapse Meshes by an Interdisciplinary Research Team Each year roughly 200,000 U.S. women undergo a surgery to repair pelvic organ prolapse (6, 7)...
  23. MOLECULAR AND BIOCHEMICAL STUDY OF COLLAGEN IN PROLAPSE
    Anthony Visco; Fiscal Year: 2002
    ..Adapted from Applicant's Description): Pelvic floor dysfunction including urinary incontinence and pelvic organ prolapse is a major health issue for women resulting in an 11 percent lifetime risk of requiring surgery...
  24. Protease regulation and integrity of connective tissues of the pelvic floor
    Hiromi Yanagisawa; Fiscal Year: 2013
    ..by applicant): Multiple mechanisms have been hypothesized to contribute to the development of pelvic organ prolapse, but none fully explain the origin and natural history of this process...
  25. Minimally Invasive Vaginal Prolapse Repair
    WALTER VON PECHMANN; Fiscal Year: 2012
    ..An outside panel of medical peers will be formed to follow the project, to provide feedback on the safety and efficiency of the approach and tooling and to suggest improvements. ..
  26. Perioperative Pelvic Floor Rehab: A Rrandomized Trial
    Holly E Richter; Fiscal Year: 2013
    ..treatment of women with pelvic floor disorders including urinary and fecal incontinence as well as pelvic organ prolapse. We have substantially contributed to the Network activities by participating at all levels of clinical trial ..
  27. Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies (ACCESS)
    ELIZABETH ROSE MUELLER; Fiscal Year: 2010
    ..Compared to standard abdominal sacrocolpopexy, the classic gold standard operation for vaginal apical prolapse, minimally-invasive robotic sacrocolpopexy has the potential to provide a safer and more precise treatment, with ..
  28. Cleveland Clinic Clinical Site
    Matthew Barber; Fiscal Year: 2013
    ..comparative effectiveness of sacrospinous hysteropexy (SSH), the most well-studied uterine-sparing pelvic organ prolapse (POP) surgery, relative to total vaginal hysterectomy with sacrospinous ligament fixation (TVH/SSLF), a commonly ..
  29. Clinical and Translational Resaerch in the Pelvic Floor Disorders Network
    Linda Brubaker; Fiscal Year: 2013
    ..RELEVANCE: American women are affected by pelvic floor disorders, including urinary incontinence, pelvic organ prolapse and fecal incontinence, yet there is insufficient clinical and translational science to provide effective, ..
  30. Adult Life Predictors of Genitourinary Disorders
    Stephen K Van Den Eeden; Fiscal Year: 2013
    ..g., urinary incontinence, pelvic organ prolapse, sexual dysfunction, lower urinary tract symptoms, and erectile dysfunction)...
  31. Mitral Regurgitation, Heart Failure and Coronary Disease: Benefits to MV Repair?
    Robert Michler; Fiscal Year: 2012
    ..Importantly, patients with organic disease of the mitral valve such as mitral valve prolapse, ruptured chordae and endocarditis will be excluded from the study...
  32. IDENTIFICATION OF GENES PREDISPOSING TO PELVIC FLOOR DISORDERS
    LISA CANNON ALBRIGHT; Fiscal Year: 2013
    ..between basic and clinical scientists in Utah to identify genes affecting predisposition to pelvic organ prolapse (POP). The co-PIs both have significant experience, Dr. Norton in Pelvic Floor Disorder (PFD) genetics and Dr...
  33. Improved Surgical Treatment of Pelvic Organ Prolapse
    KEITH LIPFORD; Fiscal Year: 2009
    The overall objective of this research and development project is to improve treatment of vaginal prolapse, a disorder of the female pelvic floor...
  34. Pelvic Floor Disorders Network
    CHARLES WILLIAM NAGER; Fiscal Year: 2013
    ..A growing-trend of women is seeking uterine sparing surgery for prolapse and a growing trend of gynecologists and urologists are managing uterine prolapse with vaginal mesh kit ..
  35. MVPS: Health Concerns, Role function, Health Service Use
    KRISTINE SCORDO; Fiscal Year: 2002
    DESCRIPTION: (provided by applicant) Mitral valve prolapse (MVP) is the most common valvular heart disease with millions of people newly diagnosed each year...
  36. CIRCULATORY CONTROL IN CHRONIC HYPOTENSIVE STATES
    ROSE ROBERTSON; Fiscal Year: 1990
    ..which overlaps clinically with "vasoregulatory" or "neurocirculatory" asthenia and a portion of the mitral valve prolapse population, and dysautonomic orthostatic hypotension (DOH), including patients with idiopathic orthostatic ..
  37. Translational Research in Pelvic Floor Disorders
    Jennifer Marie Wu; Fiscal Year: 2013
    ..My research will focus on identifying genetic risk factors for pelvic organ prolapse through a candidate gene association study (Aim 1)...
  38. NICHD Pelvic Floor Disorders Network Clinical Sites (U10)
    Joseph I Schaffer; Fiscal Year: 2013
    ..trial of intravaginal estrogen therapy as an adjunct to sacrocolpopexy for prevention of recurrent pelvic organ prolapse. We believe this trial builds on the previous work of the PFDN and addresses several key research topics ..
  39. In Situ Biomechanical Testing of the Anterior Vaginal Support System
    Yvonne Hsu; Fiscal Year: 2010
    ..In this proposal we apply biomechanical principles to investigate the pathogenesis of anterior vaginal prolapse to generate preliminary data in two distinct areas: in situ testing with dynamic MR imaging and apical support ..
  40. Mechanisms of anterior vaginal wall support failure
    John O L Delancey; Fiscal Year: 2013
    ..The goal of our proposed research is to discover the anatomical failures that cause anterior compartment (AC) prolapse. AC prolapse is clinically manifest as the inter-related problems of cystocele and uterine prolapse...
  41. Birth, Muscle Injury and Pelvic Floor Dysfunction
    John O L Delancey; Fiscal Year: 2013
    ..been known for millennia that many young women who give birth vaginally will suffer from disabling pelvic organ prolapse later in their lifespan, the factors linking these two events remain a mystery...
  42. Pelvic Floor Disorders Network Clinical Sites
    Ingrid E Nygaard; Fiscal Year: 2013
    ..in this proposal is to evaluate whether a pessary placed immediately after vaginal surgery for pelvic organ prolapse improves anatomic success compared to usual care...
  43. ECHOCARDIOGRAPHIC STROKE PREDICTORS IN A TRI-ETHNIC COMM
    Marco Di Tullio; Fiscal Year: 2003
    ..associated with less frequent abnormalities (patent foramen ovale, mitral annular calcification, mitral valve prolapse). Finally, the prevalence of a patent foramen ovale in each race-ethnic group will be evaluated...
  44. PARTURITION INDUCED PELVIC FLOOR NEUROPATHY
    KARL THOR; Fiscal Year: 2003
    Pelvic organ prolapse (descent of the bladder, vagina, and rectum) and associated bladder and bowel dysfunction are problems for many women...
  45. MODEL FOR PELVIC FLOOR DISORDERS
    Amanda Clark; Fiscal Year: 2004
    Women's health is severely impacted by pelvic organ prolapse (pop), a highly prevalent condition that results from abnormal elongation and breaks of the connective tissue of the vaginal walls and its paravaginal attachments...
  46. Epidemiology of Female Pelvic Floor Disorders
    Kristen Kjerulff; Fiscal Year: 2001
    ..Uterine prolapse is the most common indication for hysterectomy among women aged 60-79, and the second most common indication ..
  47. DUKE UNINARY CONTINENCE TREATMENT CENTER
    Richard Bump; Fiscal Year: 2000
    A woman's lifetime risk of surgery for genuine stress incontinence (GSI) or pelvic organ prolapse (POP) is 11 %, with nearly 1/3 of surgery being performed for recurrenCes...
  48. MULTICENTER NETWORK OF MATERNAL-FETAL MEDICINE UNITS
    Richard Depp; Fiscal Year: 1991
    ..distress syndrome and intraventricular hemorrhage against the intrauterine risks of infection, umbilical cord prolapse, and fetal death. Maternal infections morbidity and incidence of cesarean section will also be compared...
  49. Pelvic Floor Changes Before and After Birth
    REBECCA GLENN ROGERS; Fiscal Year: 2010
    ..Structured pelvic examinations incorporating the pelvic organ prolapse quantification system will evaluate pelvic floor anatomy...
  50. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..Urinary incontinence (UT) and pelvic organ prolapse (POP) are common health problems in older women, for which the etiologies are poorly understood...
  51. Computational Study of Fibrillins in CV Morphogenesis
    BRENDA RONGISH; Fiscal Year: 2004
    ..patients with these disorders manifest aortic root dilatation, aortic insufficiency, and mitral valve prolapse. A neonatal form of Marfan syndrome causes severe cardiovascular defects and leads to death within the first year...
  52. COMPUTATIONAL METHODS IN CARDIAC FLUID DYNAMICS
    CHARLES PESKIN; Fiscal Year: 1990
    ..valve pathology such as stenosis and regurgitation, specific syndromes involving the valves such as Mitral Valve Prolapse Syndrome and idiopathic Hypertrophic Subaortic Stenosis, and conditions in which wall motion abnormal such as ..
  53. Population Study of Pregnancy and Pelvic Floor Disorders
    Karl Luber; Fiscal Year: 2004
    ..These disorders, which include urinary incontinence, anal incontinence and pelvic organ prolapse, have a profound effect upon women's lives and impact a large percentage of the adult female population in the ..
  54. Vaginal Tactile Imager for Pelvic Floor Biomechanical Assessment
    Vladimir Egorov; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Pelvic organ prolapse is a highly prevalent condition affecting at least 50% of women in the US during their lifetimes...
  55. Novel Applications of Sarcomere Length to Improve Anal Continence
    RAVINDER MITTAL; Fiscal Year: 2009
    ..growing segment of VA health care users and pelvic floor disorders (fecal and urinary incontinence, pelvic organ prolapse) are extremely common in this patient population...
  56. A New Surgical Mesh for Pelvic Floor Reconstruction
    Simon Williams; Fiscal Year: 2005
    ..The new device is expected to address a market of 200,000 pelvic prolapse procedures in the United States, and it is anticipated that this new product could help reduce the unacceptable ..
  57. PSYCHOBIOLOGY OF ANXIETY DISORDERS
    Jack Gorman; Fiscal Year: 1991
    ..of panic during laboratory and ambulatory monitoring, continuation of work on the relationship of mitral valve prolapse to panic, collaboration in family studies of anxiety disorder using biologic probes, beginning of work to use ..
  58. ADVANCED DEVICE TO TREAT FEMALE URINARY INCONTINENCE
    Geoffrey Kotzar; Fiscal Year: 2000
    Stress urinary incontinence afflicts 20% of women. The lifetime risk of undergoing a single surgery for either prolapse or incontinence by age 80 is reported to be greater than 11%. For many women, however, surgery is not a viable option...
  59. A SYSTEM FOR MEASURING PELVIC MUSCLE STRENGTH IN WOMEN
    Neil Cole; Fiscal Year: 2003
    ..One in nine women suffer from pelvic floor dysfunction, including urinary incontinence and vaginal wall or uterine prolapse (VUP)...
  60. Population Base Multi-Ethnic Study of Pelvic Disorders
    Firouz Daneshgari; Fiscal Year: 2006
    ..risk factors of Female Pelvic Floor Disorders (FPFD: urinary incontinence, fecal incontinence, and pelvic organ prolapse) in conjunction with an on-going case-control study of breast cancer now underway...
  61. Magnetic Location System For Catheter Guidance
    Timothy Riehle; Fiscal Year: 2009
    ..localization information from points on the wire proximal to the wire tip, thus alerting the physician to wire prolapse. In phase I, Koronis Biomedical Technologies will design and fabricate a new ultra-miniature sensor for micro-..
  62. Maternal Birth-Related NeuroMuscular Injury and Recovery
    Janis Miller; Fiscal Year: 2006
    ..testing at 6-months by quantifying PCM strength (by instrumented speculum), pelvic organ support (by pelvic organ prolapse quantification) and incontinence (by standard urodynamic and survey measures)...
  63. ANXIETY AND REGIONAL CEREBRAL BLOOD FLOW
    Roy Mathew; Fiscal Year: 1990
    ..It would also explain the central mechanisms of cerebral ischemia, commonly associated with acute anxiety. Lastly, it might provide new insights into the association between anxiety, mitral valve prolapse and stroke.
  64. HUMAN ADRENERGIC RECEPTOR AND G-PROTEIN REGULATION
    Albert Davies; Fiscal Year: 1991
    ..In the dysautonomia of mitral valvular prolapse (MVP) dysautonomia), increased catecholamine responsiveness is associated with increased formation of a high ..