aspiration pneumonia

Summary

Summary: A type of pneumonia resulting from the aspiration of food, liquid, or gastric contents into the upper respiratory tract.

Top Publications

  1. ncbi Microbiology of severe aspiration pneumonia in institutionalized elderly
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine, NY, USA
    Am J Respir Crit Care Med 167:1650-4. 2003
  2. ncbi The nasogastric feeding tube as a risk factor for aspiration and aspiration pneumonia
    Guilherme F Gomes
    Departments of Gastroenterology and Surgery, Federal University of Parana, Hospital Nossa Senhora das Gracas, Curitiba, Brazil
    Curr Opin Clin Nutr Metab Care 6:327-33. 2003
  3. ncbi Aspiration pneumonia and dysphagia in the elderly
    Paul E Marik
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Chest 124:328-36. 2003
  4. ncbi Role of nasogastric tube in preventing aspiration pneumonia in patients with dysphagia
    K Mamun
    Geriatric Medicine Unit, Singapore General Hospital, Outram Road, Singapore 169608
    Singapore Med J 46:627-31. 2005
  5. ncbi Predictors of aspiration pneumonia in nursing home residents
    Susan E Langmore
    Department of Neurology, University of California San Francisco, San Francisco, California
    Dysphagia 17:298-307. 2002
  6. ncbi Reducing the risk of aspiration pneumonia among elderly patients in long-term care facilities through oral health interventions
    Jaya Sarin
    Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA
    J Am Med Dir Assoc 9:128-35. 2008
  7. ncbi Risk factors of aspiration pneumonia in Alzheimer's disease patients
    H Wada
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai, Miyagi, Japan
    Gerontology 47:271-6. 2001
  8. ncbi Aspiration pneumonia: incidence, mortality, and at-risk populations
    Mark H Delegge
    Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
    JPEN J Parenter Enteral Nutr 26:S19-24; discussion S24-5. 2002
  9. ncbi The effect of intermittent nasogastric feeding on preventing aspiration pneumonia in ventilated critically ill patients
    Yu Chih Chen
    Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Nurs Res 14:167-80. 2006
  10. ncbi Recurrent aspiration pneumonia after laparoscopic adjustable gastric banding
    M Hofer
    First Medical Department, Rudolfstiftung, Vienna, Austria
    Obes Surg 17:565-7. 2007

Detail Information

Publications207 found, 100 shown here

  1. ncbi Microbiology of severe aspiration pneumonia in institutionalized elderly
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine, NY, USA
    Am J Respir Crit Care Med 167:1650-4. 2003
    ..prospectively the microbial etiology and prognostic indicators of 95 institutionalized elders with severe aspiration pneumonia, and to investigate its relation to oral hygiene in using quantitative bronchial sampling...
  2. ncbi The nasogastric feeding tube as a risk factor for aspiration and aspiration pneumonia
    Guilherme F Gomes
    Departments of Gastroenterology and Surgery, Federal University of Parana, Hospital Nossa Senhora das Gracas, Curitiba, Brazil
    Curr Opin Clin Nutr Metab Care 6:327-33. 2003
    ..The true prevalence of aspiration is difficult to determine because of vague definitions, poor assessment methods, and varying levels of clinical recognition...
  3. ncbi Aspiration pneumonia and dysphagia in the elderly
    Paul E Marik
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Chest 124:328-36. 2003
    ..This may include swallow therapy, dietary modification, aggressive oral care, and consideration for treatment with an angiotensin-converting enzyme inhibitor...
  4. ncbi Role of nasogastric tube in preventing aspiration pneumonia in patients with dysphagia
    K Mamun
    Geriatric Medicine Unit, Singapore General Hospital, Outram Road, Singapore 169608
    Singapore Med J 46:627-31. 2005
    Every year, a large number of patients with dysphagia are placed on feeding tubes to prevent aspiration pneumonia. This prospective study was planned to compare the incidence of aspiration pneumonia and death in patients with dysphagia ..
  5. ncbi Predictors of aspiration pneumonia in nursing home residents
    Susan E Langmore
    Department of Neurology, University of California San Francisco, San Francisco, California
    Dysphagia 17:298-307. 2002
    b>Aspiration pneumonia is a serious problem for the elderly institutionalized person, often requiring transfer to a hospital and a lengthy stay there. It is associated with a high mortality rate and is very costly to the health care system...
  6. ncbi Reducing the risk of aspiration pneumonia among elderly patients in long-term care facilities through oral health interventions
    Jaya Sarin
    Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA
    J Am Med Dir Assoc 9:128-35. 2008
    b>Aspiration pneumonia is a leading cause of morbidity and mortality of elderly residents in long-term care facilities. The microflora present in the oral cavity because of poor oral hygiene has been associated with aspiration pneumonia...
  7. ncbi Risk factors of aspiration pneumonia in Alzheimer's disease patients
    H Wada
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai, Miyagi, Japan
    Gerontology 47:271-6. 2001
    ..Objectives: This study assessed swallowing function to explore the potential risk factors of aspiration pneumonia in AD patients. METHODS: Data were gathered on 121 AD patients (mean age 78.2, SD 7...
  8. ncbi Aspiration pneumonia: incidence, mortality, and at-risk populations
    Mark H Delegge
    Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
    JPEN J Parenter Enteral Nutr 26:S19-24; discussion S24-5. 2002
    ..Neurologic dysfunction, decreased consciousness, advancing age, gastroesophageal reflux, and tube feeding are all potential risk factors for the development of aspiration...
  9. ncbi The effect of intermittent nasogastric feeding on preventing aspiration pneumonia in ventilated critically ill patients
    Yu Chih Chen
    Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Nurs Res 14:167-80. 2006
    ..of a medical center to investigate the efficacy of intermittent nasogastric (NG) feeding in preventing aspiration pneumonia in critically ill patients on ventilators...
  10. ncbi Recurrent aspiration pneumonia after laparoscopic adjustable gastric banding
    M Hofer
    First Medical Department, Rudolfstiftung, Vienna, Austria
    Obes Surg 17:565-7. 2007
    ..We report a 44-year-old female suffering from dysphagia and aspiration pneumonia 2 years after adjustable banding...
  11. ncbi Epidemiology and impact of aspiration pneumonia in patients undergoing surgery in Maryland, 1999-2000
    Jeffrey H Kozlow
    Department of Anesthesiology Critical Care Medicine, The Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD, USA
    Crit Care Med 31:1930-7. 2003
    The epidemiology of aspiration pneumonia and its impact on clinical and economic outcomes in surgical patients are poorly defined...
  12. pmc Risk and outcome of aspiration pneumonia in a city hospital
    J Jones
    Howard University Medical Service, DC General Hospital, Washington, DC 20003
    J Natl Med Assoc 85:533-6. 1993
    Because aspiration pneumonia contributes significantly to morbidity and mortality in hospitalized patients, this study was undertaken to identify risk factors for morbidity and mortality associated with aspiration pneumonia...
  13. ncbi ACE inhibitors prevent aspiration pneumonia in Asian, but not Caucasian, elderly patients with stroke
    S Teramoto
    Eur Respir J 29:218-9; author reply 219-20. 2007
  14. ncbi [Association between aspiration pneumonia and malnutrition in patients from active geriatric units]
    Joanie Bouchard
    Departement de Nutrition, Faculté de médince, Universite de Montreal, Montreal, QC, Canada
    Can J Diet Pract Res 70:152-4. 2009
    To study the association between malnutrition and aspiration pneumonia (AP) in patients from active geriatric units and describe patients who developed AP.
  15. ncbi Aspiration pneumonia: dental and oral risk factors in an older veteran population
    M S Terpenning
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48105, USA
    J Am Geriatr Soc 49:557-63. 2001
    OBJECTIVES: To investigate the importance of medical and dental factors in aspiration pneumonia in an older veteran population. DESIGN: Prospective enrollment of subjects with retrospective analysis of data...
  16. ncbi Tongue-coating as risk indicator for aspiration pneumonia in edentate elderly
    Shu Abe
    Department of Microbiology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Arch Gerontol Geriatr 47:267-75. 2008
    Silent aspiration of oral microorganisms is a major cause of aspiration pneumonia. To establish oral hygiene criteria for the prevention of aspiration pneumonia in edentulous elderly persons, we investigated the relationship between ..
  17. ncbi Blockade of neutrophil responses in aspiration pneumonia via ELR-CXC chemokine antagonism does not predispose to airway bacterial outgrowth
    Xixing Zhao
    Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, Canada
    Pulm Pharmacol Ther 23:22-8. 2010
    ..Herein we assessed whether blocking neutrophil responses in a guinea pig model of aspiration pneumonia would foster airway bacterial growth...
  18. ncbi Risk of aspiration pneumonia in suspected variceal hemorrhage: the value of prophylactic endotracheal intubation prior to endoscopy
    David G Koch
    Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Dig Dis Sci 52:2225-8. 2007
    ..acute VH is a concern; however, few data exist regarding the efficacy of prophylactic intubation to prevent aspiration pneumonia. We reviewed all endoscopic procedures for acute VH from January 1995 to December 2002; only patients with ..
  19. ncbi Preanaesthetic H2 antagonists for acid aspiration pneumonia prophylaxis. Is there evidence of tolerance?
    K Hirota
    Br J Anaesth 90:576-9. 2003
  20. ncbi A traditional Chinese herbal medicine, banxia houpo tang, improves cough reflex of patients with aspiration pneumonia
    Koh Iwasaki
    J Am Geriatr Soc 50:1751-2. 2002
  21. ncbi Acute stroke predisposes to oral gram-negative bacilli -- a cause of aspiration pneumonia?
    B Millns
    Department of Dental Sciences, University of Liverpool, UK
    Gerontology 49:173-6. 2003
    To assess any change in the oral flora in the mouths of stroke patients during the acute and rehabilitation phases and to determine whether this is related to episodes of aspiration pneumonia and clinical outcome.
  22. ncbi Does the presence of esophagitis prior to PEG placement increase the risk for aspiration pneumonia?
    Matthew L Carnes
    Medical University of South Carolina, Department of Medicine, Division of Gastroenterology and Hepatology, Digestive Disease Center, Charleston, South Carolina 29425, USA
    Dig Dis Sci 49:1798-802. 2004
    The aim of this study is to determine if the endoscopic presence of esophagitis predicts aspiration pneumonia after the initiation of enteral feedings in a newly placed PEG tube...
  23. ncbi [Post stroke swallowing dysfunction and aspiration pneumonia]
    Tadashi Arai
    Arai Clinic
    Nihon Rinsho 64:463-6. 2006
  24. ncbi Nosocomial pneumonia
    Waldemar G Johanson
    UMDNJ New Jersey Medical School, 185 South Orange, Newark, NJ 07018, USA
    Intensive Care Med 29:23-9. 2003
    ..Quantitation of such specimens serves as an excellent proxy for direct cultures of the lung and are the current gold standard for diagnosis...
  25. ncbi Effect of professional oral health care on the elderly living in nursing homes
    Mieko Adachi
    Fuchu Health Center, Fuchu City, Tokyo, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:191-5. 2002
    ..We evaluated the effectiveness of professional oral health care (POHC) given by dental hygienists once a week for 24 months to 141 elderly persons needing daily care and living in 2 nursing homes...
  26. ncbi Impact of fundoplication versus gastrojejunal feeding tubes on mortality and in preventing aspiration pneumonia in young children with neurologic impairment who have gastroesophageal reflux disease
    Rajendu Srivastava
    University of Utah Health Sciences Center, Division of Inpatient Medicine, Salt Lake City, UT 84113, USA
    Pediatrics 123:338-45. 2009
    b>Aspiration pneumonia is the most common cause of death in children with neurologic impairment who have gastroesophageal reflux disease...
  27. ncbi Using a monitored test to assess risk of aspiration in postoperative patients
    Sonya Osborne
    Canberra Hospital, University of Canberra, ACT, Australia
    AORN J 83:908-12, 915-22, 925-8. 2006
    ..5%); however, no identification of patients at risk for aspiration occurred after either the use of the monitored sip test or routine cautious introduction of fluids during the data collection phase of the study...
  28. ncbi DNA identification of the pathogen of candidal aspiration pneumonia induced in the course of oral cancer therapy
    Tetsuya Yamamoto
    Department of Oral Surgery, Kochi Medical School, Kohasu, Oko cho, Nankoku City, Kochi 783 8505, Japan
    J Med Microbiol 54:493-6. 2005
    ..These results indicate that the pathogen of the pneumonia, C. albicans, was aspirated from the oral cavity and that oral Candida is easily aspirated and becomes the pathogen of pneumonia...
  29. ncbi Future considerations in aspiration pneumonia in the critically ill patient: what is not known, areas for future research, and experimental methods
    James A Disario
    Division of Gastroenterology, Hepatology, and Nutrition, University of Utah Health Sciences Center, Salt Lake City 84132, USA
    JPEN J Parenter Enteral Nutr 26:S75-8; discussion S79. 2002
    ..us define and prevent the disorder--for instance, standardized criteria should be developed for diagnosing aspiration pneumonia and for differentiating it from other types of pneumonia, and accurate tests should be devised for ..
  30. ncbi The role of anaerobes in patients with ventilator-associated pneumonia and aspiration pneumonia: a prospective study
    P E Marik
    Medical and Surgical Intensive Care Unit, St Vincent Hospital, Worcester, MA 01604, USA
    Chest 115:178-83. 1999
    ..Consequently, patients with these disorders are usually treated with antimicrobial agents with anaerobic activity...
  31. ncbi Differences in the features of aspiration pneumonia according to site of acquisition: community or continuing care facility
    M Reza Shariatzadeh
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Am Geriatr Soc 54:296-302. 2006
    To determine the prevalence of aspiration pneumonia and to compare the features and risk factors for this entity in patients from continuing care facilities (CCFs) and the community who were admitted to the hospital with pneumonia.
  32. ncbi Dysphagia and aspiration pneumonia in older adults
    Ellen Sue Eisenstadt
    Harmony Primary Care, Baltimore, Maryland 21209, USA
    J Am Acad Nurse Pract 22:17-22. 2010
    To review the risks, diagnosis, management, and prevention of aspiration pneumonia in adults over age 65, and discuss the major role of dysphagia as a risk factor in this population.
  33. ncbi Etiology and clinical outcome in dogs with aspiration pneumonia: 88 cases (2004-2006)
    David A Kogan
    Veterinary Medical Teaching Hospitaland the Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Am Vet Med Assoc 233:1748-55. 2008
    To evaluate the number and types of underlying disorders detected in dogs with aspiration pneumonia and determine the survival rate among affected dogs.
  34. pmc Pepsin as a marker for pulmonary aspiration
    Norma A Metheny
    School of Nursing, St Louis University, MO, USA
    Am J Crit Care 11:150-4. 2002
    ..A potential method is immunoassay of tracheal secretions for the gastric enzyme pepsin...
  35. ncbi Prevention of aspiration pneumonia in nursing home patients
    Margaret Terpenning
    Clin Infect Dis 40:7-8. 2005
  36. ncbi Diffuse FDG uptake in the lungs in aspiration pneumonia on positron emission tomographic imaging
    Jian Q Yu
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Nucl Med 29:567-8. 2004
  37. ncbi Involvement of periodontopathic anaerobes in aspiration pneumonia
    Katsuji Okuda
    Department of Microbiology, Oral Health Science Center, Tokyo Dental College, Chiba, Japan
    J Periodontol 76:2154-60. 2005
    Increasing evidence has linked the anaerobic bacteria forming periodontopathic biofilms with aspiration pneumonia in elderly persons...
  38. ncbi Prevention and treatment of aspiration pneumonia in intensive care units
    Thibaud d'Escrivan
    Service de Réanimation Médicale et Maladies Infectieuses, Centre Hospitalier de Tourcoing, Tourcoing, France
    Treat Respir Med 4:317-24. 2005
    ..With regard to treatment, aspiration pneumonitis does not require any antimicrobials; on the contrary, aspiration pneumonia has to be treated. Empiric antimicrobials treatment should be started on clinical suspicion...
  39. ncbi Risk factors for aspiration pneumonia after percutaneous endoscopic gastrostomy
    Toshiro Kitamura
    Department of Surgery, Municipal Kouyo Hospital, Hokuto City, Yamanashi, Japan
    Gerontology 53:224-7. 2007
    Percutaneous endoscopic gastrostomy (PEG) is generally used for long-term enteral nutrition. Patients who require PEG placement are often very sick, and postoperative complications, especially aspiration pneumonia, can be fatal.
  40. ncbi Aspiration pneumonia. Pathophysiological aspects, prevention and management. A review
    A Petroianni
    Unit of Respiratory Diseases, Policlinico Umberto I, Fondazione E Lorillard Spencer Cenci, University La Sapienza, Rome, Italy
    Panminerva Med 48:231-9. 2006
    ..preventive measures can drastically reduce the worsening of clinical conditions and the deaths due to aspiration pneumonia. Normal airway structure, effective defence mechanisms, and preventive measures are decisive in reducing ..
  41. ncbi Cardiac effects of burn injury complicated by aspiration pneumonia-induced sepsis
    Jean White
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9160, USA
    Am J Physiol Heart Circ Physiol 285:H47-58. 2003
    ..In conclusion, our data suggest that burn injury primes the subject such that a second insult early in the postburn period produces significantly greater cardiac abnormalities than those seen with either burn alone or sepsis alone...
  42. ncbi Incidence of aspiration pneumonia in ALS in Olmsted County, MN
    Eric J Sorenson
    Department of Neurology, Mayo Clinic Rochester, MN 55905, USA
    Amyotroph Lateral Scler 8:87-9. 2007
    b>Aspiration pneumonia is believed to be an uncommon complication of amyotrophic lateral sclerosis (ALS). However, the incidence of aspiration pneumonia and its contribution to morbidity and mortality are unknown in ALS...
  43. doi High incidence of aspiration pneumonia in community- and hospital-acquired pneumonia in hospitalized patients: a multicenter, prospective study in Japan
    Shinji Teramoto
    J Am Geriatr Soc 56:577-9. 2008
  44. ncbi Pharmacologic prevention of aspiration pneumonia: a systematic review
    Ali A El Solh
    Westem New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, Buffalo, New York 14215, USA
    Am J Geriatr Pharmacother 5:352-62. 2007
    b>Aspiration pneumonia is a common cause of morbidity and mortality...
  45. ncbi Effect of Seihai-to, a Kampo medicine, in relapsing aspiration pneumonia--an open-label pilot study
    N Mantani
    Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Japan
    Phytomedicine 9:195-201. 2002
    Two published case reports described palliation of disease after Seihai-to therapy for refractory aspiration pneumonia caused by recurrent laryngeal nerve paralysis and cerebrovascular disease...
  46. ncbi Interventions to prevent aspiration pneumonia in older adults: a systematic review
    Mark B Loeb
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Am Geriatr Soc 51:1018-22. 2003
    ..review was conducted to assess the effectiveness of the following interventions for prevention of aspiration pneumonia (AP) in older adults: compensatory strategy/positioning changes, dietary interventions, pharmacologic ..
  47. ncbi Aspiration syndromes: aspiration pneumonia and pneumonitis
    Paul E Marik
    Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Hosp Pract (1995) 38:35-42. 2010
    b>Aspiration pneumonia and pneumonitis are common clinical syndromes that occur in hospitalized patients...
  48. ncbi Pneumonia versus aspiration pneumonitis in nursing home residents: diagnosis and management
    Joseph M Mylotte
    Department of Medicine, Division of Infectious Diseases, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, USA
    J Am Geriatr Soc 51:17-23. 2003
    ..To determine the frequency of aspiration pneumonitis in nursing home residents with an initial diagnosis of pneumonia and to compare the clinical characteristics, management, and outcome of aspiration pneumonitis with those of pneumonia...
  49. ncbi Fatal aspiration pneumonia during transition from donepezil to rivastigmine
    Amy M Taylor
    College of Pharmacy, University of Iowa, Iowa City, IA, USA
    Ann Pharmacother 36:1550-3. 2002
    To report a case of fatal aspiration pneumonia in a patient shortly after initiation of rivastigmine and discontinuation of donepezil, with no washout period between therapies.
  50. ncbi Treatment of recurrent aspiration pneumonia in end-stage dementia: preferences and choices of a group of elderly nursing home residents
    J A Low
    Department of Geriatrics, Alexandra Hospital, Singapore
    Intern Med J 33:345-9. 2003
    ..of how best to manage patients with advanced dementia who present to the hospital with repeated episodes of aspiration pneumonia. Rarely, if at all, are the opinions of the group that is most likely to be directly affected, that is the ..
  51. ncbi Fever, cough, and bilateral lung infiltrates. Achalasia associated with aspiration pneumonia
    Nikolaos Akritidis
    Department of Internal Medicine, Hatzikosta General Hospital of Ioannina, Greece
    Chest 123:608-12. 2003
  52. ncbi [Aspiration pneumonia]
    Jordi Almirall
    Hospital de Mataró Consorci Sanitari del Maresme Mataró Barcelona Universitat Autònoma de Barcelona Barcelona España
    Med Clin (Barc) 129:424-32. 2007
    The incidence and the prevalence of aspiration pneumonia (AP) in the community is poorly defined. It increases in direct relation with age and underlying diseases...
  53. ncbi A novel diagnostic test for the risk of aspiration pneumonia in the elderly
    Shinji Teramoto
    Chest 125:801-2. 2004
  54. ncbi Effect of temperature on swallowing reflex in elderly patients with aspiration pneumonia
    Aya Watando
    J Am Geriatr Soc 52:2143-4. 2004
  55. ncbi Effects of functional training of dysphagia to prevent pneumonia for patients on tube feeding
    Koichiro Ueda
    Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Japan
    Gerodontology 21:108-11. 2004
    ..The purpose of this study was to evaluate the effects of functional training on outbreak frequency of pneumonia for the elderly dysphagia patients who were being tube fed...
  56. ncbi Silent aspiration: what do we know?
    Deborah Ramsey
    Guy s, King s and St Thomas School of Medicine, King s College, London, UK
    Dysphagia 20:218-25. 2005
    ..The phenomenon of silent aspiration is poorly understood and further research is needed to improve methods of detection and thereby better define its prevalence and prognostic significance...
  57. ncbi Tracheal pH monitoring and aspiration in acute stroke
    Joanne Clayton
    Department of Geriatric Medicine, University of Liverpool, Liverpool, Merseyside, UK
    Age Ageing 35:47-53. 2006
    ..The aim of this study was to investigate aspiration in acute stroke patients, who are safe for oral intake as assessed by bedside swallow test and videofluoroscopy, using tracheal pH monitoring...
  58. ncbi Oral health and mortality risk from pneumonia in the elderly
    S Awano
    Division of Community Oral Health Science, Department of Health Promotion, Kyushu Dental College, 2 6 1 Manazuru, Kokurakita ku, Kitakyushu 803 8580, Japan
    J Dent Res 87:334-9. 2008
    ..Therefore, the increase in teeth with periodontal pockets in the elderly may be associated with increased mortality from pneumonia...
  59. ncbi Effect of nasogastric tubes on incidence of aspiration
    Steven B Leder
    Department of Surgery, Section of Otolaryngology, Yale University School of Medicine, New Haven, CT 06520 8041, USA
    Arch Phys Med Rehabil 89:648-51. 2008
    ..To determine what effect, if any, a nasogastric (NG) tube has on occurrence of anterograde aspiration during objective evaluation of swallowing using both liquid and puree bolus consistencies...
  60. ncbi [Dysphagia: clinical management in diagnostics and therapy]
    C Storck
    Klinik für Ohren Nasen Hals und Gesichtschirurgie der Universität Zürich, Abteilung Phoniatrie, Nordtrakt II, Frauenklinikstrasse 24, 8091 Zurich
    Praxis (Bern 1994) 94:283-9. 2005
    ..It is important to recognize early signs. The general practicer is an important initiator to introduce a differential diagnostic procedure...
  61. ncbi Poor validity of residual volumes as a marker for risk of aspiration in critically ill patients
    Stephen A McClave
    Department of Medicine, University of Louisville School of Medicine, Louisville, KY, USA
    Crit Care Med 33:324-30. 2005
    ..Elevated residual volumes (RV), considered a marker for the risk of aspiration, are used to regulate the delivery of enteral tube feeding. We designed this prospective study to validate such use...
  62. pmc Comparison of 2 interventions for liquid aspiration on pneumonia incidence: a randomized trial
    Joanne Robbins
    William S Middleton Memorial Veterans Hospital, Geriatric Research Education and Clinical Center, and University of Wisconsin, Madison, Wisconsin 53705, USA
    Ann Intern Med 148:509-18. 2008
    b>Aspiration pneumonia is common among frail elderly persons with dysphagia. Although interventions to prevent aspiration are routinely used in these patients, little is known about the effectiveness of those interventions.
  63. ncbi [Etiology and therapy choices in dysphagia. Swallowing can be relearned]
    Angelika Bischoff
    MMW Fortschr Med 150:18. 2008
  64. ncbi [Characteristics and limitation of portable bedside swallowing test in elderly with dementia: comparison between the repetitive saliva swallowing test and the simple swallowing provocation test]
    Yuki Baba
    Department of Geriatric Medicine, Kyorin University, School of Medicine
    Nihon Ronen Igakkai Zasshi 42:323-7. 2005
    ..Comprehensive geriatric assessment will help to choose an alternative test for dysphagia such as SSPT which is more specific test for aspiration pneumonia.
  65. ncbi Bronchial auscultation: an effective adjunct to speech and language therapy bedside assessment when detecting dysphagia and aspiration?
    Jane L Shaw
    Speech and Language Therapy Department, Doncaster and Bassetlaw NHS Trust, Doncaster Royal Infirmary, Doncaster, United Kingdom
    Dysphagia 19:211-8. 2004
    ..BA is a potentially useful clinical tool which requires further research...
  66. ncbi Pneumonia in stroke patients with oropharyngeal dysphagia: a six-month follow-up study
    Stefano Masiero
    Department of Rehabilitation, University of Padova, Padova, Italy
    Neurol Sci 29:139-45. 2008
    ..The pneumonia was associated with absence of reflex cough after swallow, COPD, and severe impairment of consciousness and poor functional outcome...
  67. ncbi [Clinical implications of the glucose test strip method for early detection of pulmonary aspiration in nasogastric tube- fed patients]
    Hwa Soon Kim
    Department of Nursing, Inha University, Incheon
    Taehan Kanho Hakhoe Chi 34:1215-23. 2004
    ..This study was performed to test the clinical usefulness of the glucose test strip method for early detection of pulmonary aspiration in tube fed patients...
  68. ncbi Enteral tube feeding and pneumonia
    David Sheridan Gray
    Sonoma Developmental Center, Eldridge, CA, USA
    Am J Ment Retard 111:113-20. 2006
    ..We conclude that although feeding tubes do not completely prevent pneumonia, there is an immediate decrease in the incidence of pneumonia following tube placement...
  69. pmc Tracheobronchial aspiration of gastric contents in critically ill tube-fed patients: frequency, outcomes, and risk factors
    Norma A Metheny
    Saint Louis University School of Nursing, MO, USA
    Crit Care Med 34:1007-15. 2006
    ....
  70. ncbi [The lung in deglutition disorders]
    P Fraisse
    Pôle de Pathologie Thoracique, Hopitaux Universitaires, Strasbourg, France
    Rev Mal Respir 24:791-3. 2007
  71. ncbi Oropharyngeal aspiration and pneumonia in children
    Kelly Weir
    Department of Paediatrics and Child Health, University of Queensland, Herston, Queensland, Australia
    Pediatr Pulmonol 42:1024-31. 2007
    ..We conclude that the impact of OPA on development of pneumonia is considerably reduced once other factors in children with multisystem involvement are taken into account...
  72. ncbi Hyoid bone and laryngeal movement dependent upon presence of a tracheotomy tube
    Alyssa R Terk
    Department of Surgery, Section of Otolaryngology, Yale University School of Medicine, New Haven, Connecticut 06520 8041, USA
    Dysphagia 22:89-93. 2007
    ..e., hyoid bone movement and laryngeal excursion. The hypothesis that a tracheotomy tube tethers the larynx thereby preventing hyoid bone and laryngeal movement during normal swallowing is not supported...
  73. ncbi Routine evaluation for aspiration after thoracotomy for pulmonary resection
    W Brent Keeling
    Division of Cardiothoracic Surgery, University of South Florida, Tampa, Florida, USA
    Ann Thorac Surg 83:193-6. 2007
    ..The purpose of this study was to evaluate the role of a routine protocol for evaluation of oropharyngeal aspiration after thoracotomy for pulmonary resection...
  74. ncbi Analysis of respiratory complications after minimally invasive esophagectomy: preliminary observation of persistent aspiration risk
    B Zane Atkins
    Department of Surgery, Wilford Hall USAF Medical Center, San Antonio, Texas 78236 5300, USA
    Dysphagia 22:49-54. 2007
    ..Furthermore, serial evaluation of deglutition is encouraged to guide the safe and appropriate resumption of oral feeding...
  75. ncbi Dysphagia: causes, assessment, treatment, and management
    Gregory N White
    Department of Aged Care and Rehabilitation, Bankstown Lidcombe Hospital, Bankstown, New South Wales, Australia
    Geriatrics 63:15-20. 2008
    ..This article reviews the current assessment, treatment, and management techniques for dysphagia; covers new developments in research and pilot studies; and reviews the ethical issues related to treatment when prognosis is poor...
  76. ncbi Impact of swallowing therapy on aspiration rate following treatment for locally advanced head and neck cancer
    Nam P Nguyen
    Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, VA North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
    Oral Oncol 43:352-7. 2007
    ..However, a significant number of patients still suffered from chronic severe aspiration. New strategies must be devised to improve their outcome...
  77. ncbi [Effects of one-way speaking valve placement on swallowing physiology for tracheostomized patients: impact on laryngeal clearance]
    Yukio Ohmae
    Department of Otorhinolaryngology, National Defense Medical Collage, Tokorozawa
    Nihon Jibiinkoka Gakkai Kaiho 109:594-9. 2006
    ..We concluded that one-way speaking valve placement improves laryngeal clearance and prevents laryngeal penetration, resulting in better oropharyngeal swallowing physiology and oral feeding...
  78. ncbi Aspiration rate following chemoradiation for head and neck cancer: an underreported occurrence
    Nam P Nguyen
    Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75216, USA
    Radiother Oncol 80:302-6. 2006
    ..We would like to assess the prevalence of aspiration before and following chemoradiation for head and neck cancer...
  79. ncbi Dysphagia in the elderly--a management challenge for nurses
    Heather Morris
    Br J Nurs 15:558-62. 2006
    ..nutritional status, complicating the administration of solid medications, increasing the risk of aspiration pneumonia and undermining the quality of life...
  80. ncbi Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer
    David I Rosenthal
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:2636-43. 2006
    ..Specific recommendations are made to promote maintenance and recovery of swallowing function...
  81. ncbi Functional outcomes after organ preservation treatment in head and neck cancer: a critical review of the literature
    J M Rieger
    Craniofacial Osseointegration and Maxillofacial Prosthetic Rehabilitation Unit COMPRU, Edmonton, Alta, Canada
    Int J Oral Maxillofac Surg 35:581-7. 2006
    ..Speech does not appear to be affected to the same degree as swallowing. These results suggest that organ preservation does not translate into function preservation for all patients with head and neck cancer...
  82. pmc A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson's disease
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, 3 358, Evanston, IL 60208, USA
    J Speech Lang Hear Res 51:173-83. 2008
    ....
  83. ncbi An unusual cause of aspiration pneumonia
    Stefano Masiero
    Department of Physical Medicine, University of Padova, Padova, Italy
    Aging Clin Exp Res 18:78-82. 2006
    ..The aspiration pneumonia probably had multifactorial etiology: dysphagia, abnormal cough reflex, colonization of the oropharynx by ..
  84. ncbi Comparison of the glottic closure reflex in traditional "open" versus endoscopic laser supraglottic laryngectomy
    Clarence T Sasaki
    Section of Otolaryngology, Dept of Surgery, Yale School of Medicine, 333 Cedar St, PO Box 208041, New Haven, CT 06520 8041, USA
    Ann Otol Rhinol Laryngol 115:93-6. 2006
    ..Conversely, ELSL results in the resumption of serviceable swallowing within 2 to 7 days after surgery...
  85. ncbi Stage transition duration in patients poststroke
    Youngsun Kim
    School of Hearing, Speech and Language Sciences, College of Health and Human Services, Ohio University, Athens, Ohio 45701 2979, USA
    Dysphagia 22:299-305. 2007
    ..Nonaspirating stroke participants had similar patterns to the normal subjects. Implications for these findings are discussed...
  86. pmc Management of dysphagia
    Irene Campbell-Taylor
    CMAJ 170:1078-9; author reply 1079, 1082. 2004
  87. ncbi [Management of dysphagia in the institutionalized elderly patient: current situation]
    J J Botella Trelis
    Geriatra, Medico Adjunto, Servicio de Medicina Interna
    Nutr Hosp 17:168-74. 2002
    ..Etiology, characteristics and complications of dysphagia were studied as well as the most frequently used strategies to improve the management of swallowing disorders...
  88. ncbi Diagnostic methods for the detection of anterograde aspiration in enterally fed patients
    Guilherme F Gomes
    Department of Gastroenterology, Federal University of Parana and Hospital Nossa Senhora das Graças, Curitiba, Brazil
    Curr Opin Clin Nutr Metab Care 7:285-92. 2004
    ..This review examines the most recent studies and developments in the field with an approach to the technical aspects of diagnostic methods...
  89. ncbi Altered Swallowing Physiology and Aspiration in COPD
    Shinji Teramoto
    Chest 122:1104-5; author reply 1105. 2002
  90. pmc Management of dysphagia
    Fred Saibil
    CMAJ 170:1079; author reply 1079, 1082. 2004
  91. pmc Rehabilitation medicine: 2. Diagnosis of dysphagia and its nutritional management for stroke patients
    Hillel M Finestone
    Stroke Rehabilitation Program, Department of Physical Medicine and Rehabilitation, Elisabeth Bruyere Health Centre, University of Ottawa, Ottawa, ON
    CMAJ 169:1041-4. 2003
    ..and other neurological deficits that could affect their nutritional and hydration status and lead to aspiration pneumonia. Impaired nutritional status is associated with reduced functional improvement, increased complication ..
  92. ncbi [Deglutition disorders following a stroke: what to attend to in nursing care of the patient]
    Paul van Keeken
    Pflege Z 55:suppl 2-4. 2002
  93. ncbi Dysphagia following chemoradiation for locally advanced head and neck cancer
    N P Nguyen
    Radiation Oncology, VA North Texas Health Care System, Dallas 75216, USA
    Ann Oncol 15:383-8. 2004
    ..To assess the prevalence, severity and morbidity of dysphagia following concurrent chemoradiation for head and neck cancer...
  94. ncbi Oropharyngeal aspiration in pediatric patients with endotracheal intubation
    Sérgio L Amantéa
    Pediatric Emergency Room, Hospital da Criança Santo Antônio, Complexo Santa Casa, Porto Alegre, RS, Brazil
    Pediatr Crit Care Med 5:152-6. 2004
    ..To determine the prevalence and factors associated with oropharyngeal aspiration in pediatric patients submitted to mechanical ventilation and endotracheal intubation...
  95. ncbi Videofluoroscopic and manometric evaluation of swallowing function in patients with multiple system atrophy
    Ryuzaburo Higo
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Ann Otol Rhinol Laryngol 112:630-6. 2003
    ..Although findings of videofluoroscopy were not correlated with a history of aspiration pneumonia, severity of disease was significantly correlated with a history of aspiration pneumonia...
  96. ncbi Evaluation of percutaneous endoscopic gastrostomy in elderly patients with silicosis and co-morbidities
    Masaya Kawano
    Department of Internal Medicine, Nagato Memorial Hospital, 1 11 59 Tsuruoka, Saiki 879 0835, Japan
    Kurume Med J 50:81-5. 2003
    ..Tube feeding through the PEG was not performed in three cases because of repeated aspiration pneumonia. The mean duration of PEG usage was 9 months, ranging from 5 to 20 months...
  97. ncbi Characteristics of dysphagia in elderly patients requiring mechanical ventilation
    Lori A Davis
    Department of Communication Disorders, University of Tulsa, Tulsa, Oklahoma 74104, USA
    Dysphagia 19:7-14. 2004
    ..Due to the lack of reliable clinical evaluation measures, the MBSS is necessary for differential diagnosis of dysphagia and dietary recommendations for these individuals...
  98. ncbi Gastro-oesophageal reflux in mechanically ventilated patients: effects of an oesophageal balloon
    M Orozco-Levi
    Servei de Pneumologia, Hospital del Mar, and Unitat de Recerca Respiratòria i Ambiental, IMIM, Barcelona, Spain
    Eur Respir J 22:348-53. 2003
    ..Although the method was found to be safe when applied for 8 h, longer times should be considered with caution...
  99. ncbi Critical care nutrition: reducing the risk of aspiration
    Stephen A McClave
    Division of Gastroenterology Hepatology, University of Louisville School of Medicine, 550 S Jackson St, Louisville, KY 40202, USA
    Semin Gastrointest Dis 14:2-10. 2003
    ..While aspiration is a fairly common event for critically ill patients on enteral tube feeding, progression to aspiration pneumonia is difficult to predict due to variation in host factors and characteristics of the aspirate material...
  100. ncbi Incidence and risk factors for oropharyngeal aspiration in mechanically ventilated infants and children
    Kathleen L Meert
    Pediatr Crit Care Med 5:194-6. 2004
  101. ncbi Laryngotracheal separation for intractable aspiration pneumonia in neurologically impaired children: experience with 11 cases
    Shigeru Takamizawa
    Department of Surgery, Kobe Children s Hospital, Kobe, Japan
    J Pediatr Surg 38:975-7. 2003
    ..separation (LTS) with or without end-to-side laryngoesophagostomy was performed as an antiaspiration procedure for intractable aspiration pneumonia in 11 children. The effectiveness of LTS for preventing aspiration was investigated.

Research Grants60

  1. COORDINATION OF RESPIRATION AND DEGLUTITION
    ADRIENNE PERLMAN; Fiscal Year: 2003
    ..healthy individuals or in persons, such as stroke patients, who are known to be at high risk for developing aspiration pneumonia. Using respirodeglutometry, this research will characterize the joint timing of respiration with the ..
  2. PASSY-MUIR SWALLOWING SELF TRAINING DEVICE TO ENCHANCE RECOVERY POST STROKE
    CHRISTY LESLIE LUDLOW; Fiscal Year: 2012
    ..the device at home for daily self training, they improved their oral intake without risk-none developed aspiration pneumonia over 12 months of device use...
  3. Neural Substrates of Oral Motor Dysfunction in Parkinson's Disease
    EMILY KATE PRINE; Fiscal Year: 2010
    ..by applicant): Speech and swallowing impairments occur in 90% of Parkinson's Disease (PD) patients and aspiration pneumonia is the leading cause of death...
  4. Oral Health Intervention for Intellectually/Developmentally Disabled Persons
    KNOWLTON WILLIAM JOHNSON; Fiscal Year: 2012
    ..importantly, poor oral health in persons with IDD may also contribute to respiratory infections including aspiration pneumonia. The oral health of this population is compromised not only by the lack of preventive dental treatment ..
  5. Oral Home Telecare for Tetraplegics
    Hon K Yuen; Fiscal Year: 2010
    ..Poor oral health compounded with impaired respiratory function in this population may increase the risk of aspiration pneumonia. The aims of this study are to gather preliminary evidence on the effectiveness of an oral home telecare ..
  6. Accuracy of Examining Cough Function and its Relationship to Airway Protection
    CHRISTINE M contact SAPIENZA; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Dysphagia and aspiration pneumonia are the main cause of life-threatening morbidity in Parkinson's disease (PD)...
  7. Accuracy of Examining Cough Function and its Relationship to Airway Protection
    Christine M Sapienza; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Dysphagia and aspiration pneumonia are the main cause of life-threatening morbidity in Parkinson's disease (PD)...
  8. Manual Control of the Upper Esophageal Sphincter
    Peter Belafsky; Fiscal Year: 2013
    ..Untreated dysphagia can lead to dehydration, malnutrition, aspiration pneumonia, and death...
  9. Benzodiazepine Analogs as Novel Treatments for Catatonia
    HOWARD P SARD; Fiscal Year: 2012
    ..of ailments including bed sores, deep venous thrombi, pulmonary emboli, urinary retention, infection, and aspiration pneumonia, which can lead to severe medical impairment and death...
  10. Associations between laryngeal and cough dysfunction in bulbar amyotrophic latera
    Deanna Britton; Fiscal Year: 2012
    ..Difficulty with coughing and clearing secretions contributes to risk for aspiration pneumonia and respiratory failure...
  11. Multiscale mechanisms of lingual mechanical function
    Richard J Gilbert; Fiscal Year: 2013
    ..and patients with neurological diseases, and may be responsible for malnutrition and increased risk of aspiration pneumonia in these patients...
  12. Identifying and Treating Arousal-Related Deficits in Neglect and Dysphagia
    Mark S Mennemeier; Fiscal Year: 2010
    ..and they place patients at increased risk for additional injury and hospitalization due either to falls or aspiration pneumonia, respectively. There is no widely effective form of pharmacological treatment for either disorder...
  13. Dissociating the Neural Substrates of Cranial and Limb Motor Impairment in an Ani
    EMILY KATE PLOWMAN; Fiscal Year: 2013
    ..Speech and swallowing impairments occur in 90% of individuals with Parkinson's Disease (PD) and aspiration pneumonia constitutes the leading cause of death in this patient population...
  14. Aspiration Pneumonia in Children with Neurological Impairment
    Rajendu Srivastava; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Aspiration pneumonia (AP) is the most common cause of death in children with severe neurological impairment (Nl)...
  15. DYSPHAGIA THERAPY FOLLOWING STROKE--CONTROLLED TRIAL
    Michael Reding; Fiscal Year: 1992
    ..protection should obviate many of the problems which plague rehabilitation efforts: Dehydration, inanition, aspiration pneumonia, death, and poor recovery of self-care and mobility function following stroke...
  16. Predicting Pediatric Risk of Death After Hospitalization
    JOHN FEUDTNER; Fiscal Year: 2005
    ..or classes of patients (eg, those with cerebral palsy and the first or second hospitalization for an aspiration pneumonia) suitable for quality of care assessment and improvement, with targeted intensive care coordination to ..
  17. Lingual Mechanical Function During Swallowing
    Richard Gilbert; Fiscal Year: 2005
    ..stroke, Parkinson's disease, and dementia, and are responsible for impaired nutrition and increased risk of aspiration pneumonia in these patient populations...
  18. OXYGEN TRANSPORT IN RESPIRATORY FAILURE
    Paul Schumacker; Fiscal Year: 1990
    ..an abnormal relationship between O2 delivery and uptake; (2) whether patients with localized lung injury (aspiration pneumonia) demonstrate the same abnormal O2 extraction capacity...
  19. Statewide Efforts to Improve Care in Intensive Care Unit
    Peter Pronovost; Fiscal Year: 2004
    ..we can improve patient safety; improve safety culture; and reduce ICU mortality, blood stream infections, aspiration pneumonia and ICU length of stay...
  20. DYSPHAGIA IN ALZHEIMER'S DISEASE
    Jennifer Horner; Fiscal Year: 1992
    Non-cognitive symptoms of Alzheimer's disease (AD) include feeding abnormalities, and aspiration pneumonia. Though dysphagia is generally recognized to be a major contributor to morbidity in Alzheimer's dementia, information about this ..
  21. DETECTING ASPIRATION ASSOCIATED WITH TUBE FEEDINGS
    Norma Metheny; Fiscal Year: 2007
    ..Delivery, receipt and enactment of the ARRP will be evaluated by quantitative and qualitative methods. [unreadable] [unreadable] [unreadable]..
  22. Development of a 'Nurse-Friendly' Bedside Test for Aspiration
    Norma A Metheny; Fiscal Year: 2010
    ..they cumulatively lead to pulmonary problems (such as chemical pneumonitis or potentially life-threatening aspiration pneumonia). At present, there is no reliable bedside test for aspiration...
  23. Host response to post-operative pneumonia
    Paul Knight; Fiscal Year: 2005
    ....
  24. Comprehensive Research Training for Oral Health Sciences
    Frank Scannapieco; Fiscal Year: 2008
    ..Name Organization Frank A. Scannapieco University at Buffalo/Oral Biology Libuse Bobek University at Buffalo/Oral Biology Rosemary Dziak University at Buffalo/Oral Biology in the format shown below. Role on ..
  25. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2008
    ..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..
  26. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2006
    ..abstract_text> ..
  27. Reinnervation of Paralyzed Muscle by Nerve-Muscle-Endplate Band Grafting
    Liancai Mu; Fiscal Year: 2011
    ..Our preliminary work showed that this technique results in better outcomes than currently used methods. The data obtained from this research is useful for future clinical application to treat muscle paralysis. ..
  28. Pneumococcal immunization through a novel mechanism
    Richard Malley; Fiscal Year: 2010
    ..abstract_text> ..
  29. Oropharyngeal Function After Radiotherapy with IMRT
    Jerilyn A Logemann; Fiscal Year: 2010
    ..This project attempts to quantify the swallow problems associated with this specific treatment and the effects of interventions for these swallow problems. ..
  30. IGF-I/ALS Trial
    Eric Sorenson; Fiscal Year: 2007
    ..The preliminary data from our prior trial allows design of a phase III treatment trial that will yield a definitive result about the treatment effect of IGF-I. ..
  31. CONTROL OF BREATHING IN RECOVERY FROM APNEA
    Bradley Thach; Fiscal Year: 2008
    ..Louis, MO.) of infants dying suddenly and unexpectedly to determine if post mortem body temperature indicates involvement of overheating or disorders of thermoregulation in SIDS. [unreadable] [unreadable]..
  32. Critical Role of Alveolar Fibrin in Acute Lung Injury
    Gilman Allen; Fiscal Year: 2008
    ..abstract_text> ..
  33. Sedation Effects in Mechanically Ventilated Patients
    Mary Jo Grap; Fiscal Year: 2009
    ..abstract_text> ..
  34. Effects of LSVT on Dysphagia in Parkinson's Disease
    Jerilyn Logemann; Fiscal Year: 2003
    ..This application proposes to generate pilot data on the effects of LSVT on aspiration, a potentially dangerous and costly side effect of dysphagia in Parkinson's disease. ..
  35. Siblings With Ischemic Stroke Study (SWISS)
    JAMES MESCHIA; Fiscal Year: 2009
    ..DNA banking and the creation of permanent lymphoblastoid cell lines will be done to permit future collaborative efforts to study the genetic basis for stroke risk. ..
  36. Jo-1-specific T Cell Responses in Polymyositis
    DANA ASCHERMAN; Fiscal Year: 2007
    ..These studies are intended to also provide insight concerning the relative roles of altered T cell repertoire and antigen presentation in the expression of Jo-1+ polymyositis. ..
  37. Neuro-Immune Interactions in Developing Airways
    Gary Larsen; Fiscal Year: 2005
    ..These studies of developmental airway biology in mammalian species allow definition of neuro-immune mechanisms that may have relevance to events that occur in infants and small children. ..
  38. Pneumolysin, Innate and Acquired Immunity to Pneumococci
    Richard Malley; Fiscal Year: 2005
    ..The establishment of a link between the innate and the acquired arm of the immune response to pneumococcus may provide a better understanding of the mechanisms by which immunity to pneumococcus is acquired. ..
  39. QUANTITATIVE FUNCTION IN MOTOR NEURON DISEASE
    Eric Sorenson; Fiscal Year: 2004
    ..This will become increasingly important as our population ages, increasing demands for medical and social resources. ..
  40. Oral Care and Respiratory Pathogen Colonization
    Ozan Akca; Fiscal Year: 2004
    ..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
  41. Increasing Screening Colonoscopy Among Minority Women
    Moshe Shike; Fiscal Year: 2004
    ..Demonstration of the feasibility of this model can form the basis for a nationwide project using mammography centers to enhance CRCS. ..
  42. Chemoprevention of Duodenal Polyps in FAP
    James DiSario; Fiscal Year: 2003
    ..A 5-year study is proposed. The randomized treatment period is 1 year. There will be a 6 month termination phase to include data analysis, manuscript preparation and closure of all study procedures. ..
  43. Development of a Registry for Familial Pancreatic Cancer
    James DiSario; Fiscal Year: 2003
    ..The goal corresponds with the National Cancer Institute Initiative to "identify, characterize, and understand the genes that cause or play a role in familial cancer." ..
  44. Administrative Data and General Comorbidity Models
    George Stukenborg; Fiscal Year: 2002
    ..In the fourth stage, we will compare the statistical performance of the developed models to that of other comparable methods (Deyo/Charlson method and the Elixhauser et al. Method) in each study population. ..
  45. RESPIRATORY AND LARYNGEAL DYNAMICS DURING SWALLOW
    Bonnie Martin Harris; Fiscal Year: 2002
    ..Cluster analysis will be applied to identify critical clusters of respiratory-swallowing dynamics. Mixed- effects analysis of variance will estimate the key study parameters of age group specific durations and variability. ..
  46. TREATING PERIODONTAL INFECTION: GLYCEMIC CONTROL
    George Taylor; Fiscal Year: 2002
    ..abstract_text> ..
  47. Diabetes Associations with Caries and Tooth Loss
    George Taylor; Fiscal Year: 2005
    ..Results may also impact on existing clinical practice protocols, and promote new public policy in matters related to diabetes. ..
  48. Effects of Swallowing Therapy in Head and Neck Cancer
    Jerilyn Logemann; Fiscal Year: 2006
    ....
  49. Periodontal Therapy: Effects on Glycemic Control in Community Health Centers
    George Taylor; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  50. Oropharyngeal Bolus Flow Dynamics
    Mark Nicosia; Fiscal Year: 2008
    ..This behavior may transport oral bacteria to the lungs and is a risk factor for aspiration pneumonia, a serious and often life-threatening health concern for the institutionalized and hospitalized geriatric ..
  51. Measurement model for respiratory-swallowing impairment
    Bonnie Martin Harris; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  52. A randomized trial of influenza vaccination of Hutterite children
    Mark Loeb; Fiscal Year: 2006
    ..We believe that the trial we propose will lead to important data that can inform policy on influenza immunization strategy. [unreadable] [unreadable] [unreadable]..
  53. DYSRHYTHMIAS OF THE RESPIRATORY OSCILLATOR
    David Paydarfar; Fiscal Year: 2002
    ....
  54. MECHANISMS OF CELL INJURY IN BURN COMPLICATED BY SEPSIS
    Deborah Carlson; Fiscal Year: 2006
    ..The proposed work focuses on five specific aims to increase our understanding of the cellular events involved in burn and sepsis-related myocardial injury. ..
  55. Physiology of Swallowing and Airway Protection
    David Paydarfar; Fiscal Year: 2006
    ..We will stimulate the ISLN (using optimum parameters from Aim 3) in patients with neurogenic dysphagia caused by focal cerebral damage, and we will test for improvement in swallowing and decrease in aspiration. ..
  56. Role of Cytokines in Two Hit Organ Injury
    Jean Nemzek; Fiscal Year: 2006
    ..Successful completion of these aims could impact current two hit theories and use of immune therapy in septic patients exposed to additional inflammatory insults. ..
  57. ISGS: The Ischemic Stroke Genetics Study
    JAMES MESCHIA; Fiscal Year: 2006
    ..The application and SWISS share the same definitions for the present and absence of phenotype and key enrollment criteria. ..
  58. Discharge Planning and Telehealth for Post CABG Elders
    Ruth Kleinpell; Fiscal Year: 2009
    ....
  59. Stadardized Assesment of Swallowing Impairment
    Bonnie Martin Harris; Fiscal Year: 2007
    ..abstract_text> ..