pulmonary coin lesion

Summary

Summary: Solitary, round, circumscribed shadows found in the lungs in x-ray examinations. Common causes are tuberculosis, neoplasms, cysts, or vascular anomalies. (Stedman, 25th ed)

Top Publications

  1. ncbi Evidence for the treatment of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition)
    Momen M Wahidi
    Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Box 3683, Durham, NC 27710, USA
    Chest 132:94S-107S. 2007
  2. ncbi Management of lung nodules detected by volume CT scanning
    Rob J van Klaveren
    Department of Pulmonology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    N Engl J Med 361:2221-9. 2009
  3. ncbi Subsolid pulmonary nodules and the spectrum of peripheral adenocarcinomas of the lung: recommended interim guidelines for assessment and management
    Myrna C B Godoy
    Department of Radiology, New York University Langone Medical Center, 560 First Ave, IRM 236, New York, NY 10016, USA
    Radiology 253:606-22. 2009
  4. ncbi Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society
    Heber Macmahon
    Radiology 237:395-400. 2005
  5. ncbi A new computationally efficient CAD system for pulmonary nodule detection in CT imagery
    Temesguen Messay
    Department of Electrical and Computer Engineering, University of Dayton, 300 College Park, Dayton, OH 45469 0232, United States
    Med Image Anal 14:390-406. 2010
  6. ncbi Pulmonary ground-glass nodules: increase in mass as an early indicator of growth
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 255:199-206. 2010
  7. ncbi Three-dimensional segmentation and growth-rate estimation of small pulmonary nodules in helical CT images
    William J Kostis
    Department of Radiology, Weill Medical College, Cornell University, New York, NY 10021, USA
    IEEE Trans Med Imaging 22:1259-74. 2003
  8. ncbi A large-scale evaluation of automatic pulmonary nodule detection in chest CT using local image features and k-nearest-neighbour classification
    K Murphy
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Med Image Anal 13:757-70. 2009
  9. ncbi Segmentation of pulmonary nodules of various densities with morphological approaches and convexity models
    Toshiro Kubota
    Mathematical Sciences, Susquehanna University, Selinsgrove, PA 17870, USA
    Med Image Anal 15:133-54. 2011
  10. ncbi Nodular ground-glass opacity at thin-section CT: histologic correlation and evaluation of change at follow-up
    Chang Min Park
    Department of Radiology, Seoul National University College of Medicine and the Institute of Radiation Medicine, Seoul National University Medical Research Center, 28 Yeongeon dong, Jongno gu, Seoul, Republic of Korea
    Radiographics 27:391-408. 2007

Research Grants

  1. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael K Gould; Fiscal Year: 2011
  2. Ventilator-induced diaphragm dysfunction
    SANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010
  3. Thin Film Magnetic Sensors for Ultrathin Bronchoscope Navigation
    Timothy Riehle; Fiscal Year: 2009
  4. Dynamic contrast-enhanced MRI of pulmonary nodule at 3T
    Hiroto Hatabu; Fiscal Year: 2007
  5. COMPUTER AIDED DIAGNOSIS IN CT OF THE THORAX
    Samuel Armato; Fiscal Year: 2004
  6. Standard Database for CT Lung Images
    Samuel Armato; Fiscal Year: 2006
  7. Computerized Analysis of Mesothelioma on CT Scans
    Samuel Armato; Fiscal Year: 2009
  8. 3D Massive Training ANN for CAD for Colon Cancer in CT Colonography
    Kenji Suzuki; Fiscal Year: 2010
  9. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
  10. Medical Image Perception Society Confrence XI
    Elizabeth Krupinski; Fiscal Year: 2005

Detail Information

Publications245 found, 100 shown here

  1. ncbi Evidence for the treatment of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition)
    Momen M Wahidi
    Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Box 3683, Durham, NC 27710, USA
    Chest 132:94S-107S. 2007
    ..The solitary pulmonary nodule (SPN) is a frequent incidental finding that may represent primary lung cancer or other malignant or benign lesions. The optimal management of the SPN remains unclear...
  2. ncbi Management of lung nodules detected by volume CT scanning
    Rob J van Klaveren
    Department of Pulmonology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    N Engl J Med 361:2221-9. 2009
    ....
  3. ncbi Subsolid pulmonary nodules and the spectrum of peripheral adenocarcinomas of the lung: recommended interim guidelines for assessment and management
    Myrna C B Godoy
    Department of Radiology, New York University Langone Medical Center, 560 First Ave, IRM 236, New York, NY 10016, USA
    Radiology 253:606-22. 2009
    ..It is anticipated that interim guidelines may serve to standardize our current management of these lesions, pending further clarification of their natural history...
  4. ncbi Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society
    Heber Macmahon
    Radiology 237:395-400. 2005
    ....
  5. ncbi A new computationally efficient CAD system for pulmonary nodule detection in CT imagery
    Temesguen Messay
    Department of Electrical and Computer Engineering, University of Dayton, 300 College Park, Dayton, OH 45469 0232, United States
    Med Image Anal 14:390-406. 2010
    ..4% of the nodules (115/143) using 40 selected features. A 7-fold cross-validation performance analysis using the LIDC database only shows CAD sensitivity of 82.66% with an average of 3 FPs per CT scan/case...
  6. ncbi Pulmonary ground-glass nodules: increase in mass as an early indicator of growth
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 255:199-206. 2010
    ..To compare manual measurements of diameter, volume, and mass of pulmonary ground-glass nodules (GGNs) to establish which method is best for identifying malignant GGNs by determining change across time...
  7. ncbi Three-dimensional segmentation and growth-rate estimation of small pulmonary nodules in helical CT images
    William J Kostis
    Department of Radiology, Weill Medical College, Cornell University, New York, NY 10021, USA
    IEEE Trans Med Imaging 22:1259-74. 2003
    ..The methods presented are promising in their ability to distinguish malignant from nonmalignant pulmonary nodules and represent the first such system in clinical use...
  8. ncbi A large-scale evaluation of automatic pulmonary nodule detection in chest CT using local image features and k-nearest-neighbour classification
    K Murphy
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Med Image Anal 13:757-70. 2009
    ..2 false-positives per scan is achieved. The detection results presented are a realistic measure of a CAD system performance in a low-dose screening study which includes a diverse array of nodules of many varying sizes, types and textures...
  9. ncbi Segmentation of pulmonary nodules of various densities with morphological approaches and convexity models
    Toshiro Kubota
    Mathematical Sciences, Susquehanna University, Selinsgrove, PA 17870, USA
    Med Image Anal 15:133-54. 2011
    ..The experiments show that the algorithm is highly reliable in segmenting nodules of various types in a computationally efficient manner...
  10. ncbi Nodular ground-glass opacity at thin-section CT: histologic correlation and evaluation of change at follow-up
    Chang Min Park
    Department of Radiology, Seoul National University College of Medicine and the Institute of Radiation Medicine, Seoul National University Medical Research Center, 28 Yeongeon dong, Jongno gu, Seoul, Republic of Korea
    Radiographics 27:391-408. 2007
    ..A meticulous evaluation of those CT features, and their correlation with specific histopathologic characteristics, also may enable a more accurate prognosis in cases of neoplastic disease...
  11. ncbi Pulmonary nodules at chest CT: effect of computer-aided diagnosis on radiologists' detection performance
    Kazuo Awai
    Department of Radiology, Kinki University School of Medicine, 377 2 Oono Higashi, Osaka Sayama City, Osaka 589 8511, Japan
    Radiology 230:347-52. 2004
    ..To evaluate the effect of computer-aided diagnosis (CAD) on radiologists' detection of pulmonary nodules...
  12. pmc Noncalcified lung nodules: volumetric assessment with thoracic CT
    Marios A Gavrielides
    National Institute of Biomedical Imaging and Bioengineering Center for Devices and Radiological Health, U S Food and Drug Administration, Silver Spring, MD 20993 0002, USA
    Radiology 251:26-37. 2009
    ....
  13. ncbi Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation
    D F Yankelevitz
    Department of Radiology, New York Presbyterian Hospital Weill Cornell Medical Center, Building Starr 8A23, 525 E 68th St, New York, NY 10021, USA
    Radiology 217:251-6. 2000
    ..To determine the accuracy of high-resolution computed tomographic (CT) volumetric measurements of small pulmonary nodules to assess growth and malignancy status...
  14. ncbi Lung cancer: performance of automated lung nodule detection applied to cancers missed in a CT screening program
    Samuel G Armato
    Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637, USA
    Radiology 225:685-92. 2002
    ..To evaluate the performance of a fully automated computerized method for the detection of lung nodules in computed tomographic (CT) scans in the identification of lung cancers that may be missed during visual interpretation...
  15. ncbi Dual time point 18F-FDG PET for the evaluation of pulmonary nodules
    Alexander Matthies
    Division of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Nucl Med 43:871-5. 2002
    ..18F-FDG PET has reached widespread application in the assessment of pulmonary nodules. This study compares the diagnostic accuracy of standard 18F-FDG PET scanning with those of dual time point 18F-FDG PET scanning...
  16. ncbi Surface normal overlap: a computer-aided detection algorithm with application to colonic polyps and lung nodules in helical CT
    David S Paik
    Department of Radiology, Stanford University, Stanford, CA 94305 5450, USA
    IEEE Trans Med Imaging 23:661-75. 2004
    ..It is able to achieve 100% sensitivity for colonic polyps 10 mm and larger at 7.0 false positives (FPs)/dataset and 90% sensitivity for solid lung nodules 6 mm and larger at 5.6 FP/dataset...
  17. ncbi Accuracy of PET for diagnosis of solid pulmonary lesions with 18F-FDG uptake below the standardized uptake value of 2.5
    Yaichiro Hashimoto
    Division of Nuclear Medicine, Department of Radiology, School of Medicine, Tokyo Women s Medical University, Tokyo, Japan
    J Nucl Med 47:426-31. 2006
    ..5. However, the frequency of malignancies with an SUV of <2.5 is significant, and pulmonary nodules with low 18F-FDG uptake often present diagnostic challenges...
  18. ncbi Computer-aided diagnosis of pulmonary nodules using a two-step approach for feature selection and classifier ensemble construction
    Michael C Lee
    Philips Research North America, 345 Scarborough Road, Briarcliff Manor, NY 10510 2099, USA
    Artif Intell Med 50:43-53. 2010
    ....
  19. ncbi Pulmonary nodule detection on MDCT images: evaluation of diagnostic performance using thin axial images, maximum intensity projections, and computer-assisted detection
    A Jankowski
    Service Central de Radiologie et d Imagerie Médicale, CHU Grenoble, BP 217, 38043, Grenoble Cedex 09, France
    Eur Radiol 17:3148-56. 2007
    ..0001). MIP and CAD reduced the number of overlooked small nodules. As MIP is more sensitive and less time consuming than the CAD we used, we recommend viewing MIP and 1-mm images for the detection of pulmonary nodules...
  20. ncbi Pulmonary epithelial-myoepithelial tumor of unproven malignant potential: report of a case and review of the literature
    G Pelosi
    Department of Pathology and Laboratory Medicine, European Institute of Oncology and University of Milan School of Medicine, Italy
    Mod Pathol 14:521-6. 2001
    ..In addition, we first introduce p63 as a novel marker for highlighting the myoepithelial cells of the respiratory tract and speculate on the role of these cells in the development of this unusual tumor...
  21. ncbi A comparison of six software packages for evaluation of solid lung nodules using semi-automated volumetry: what is the minimum increase in size to detect growth in repeated CT examinations
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Utrecht, The Netherlands
    Eur Radiol 19:800-8. 2009
    ..5%-25.6%). Segmented volumes of each package were compared to each of the other packages. Systematic volume differences were detected in 11/15 comparisons. This hampers comparison of nodule volumes between software packages...
  22. ncbi CT screening for lung cancer: suspiciousness of nodules according to size on baseline scans
    Claudia I Henschke
    Department of Radiology and Medicine, Weill Medical College of Cornell University, 525 E 68th St, New York, NY 10021, USA
    Radiology 231:164-8. 2004
    ..0 mm in diameter identified on initial computed tomographic (CT) images at baseline screening leads to a diagnosis of malignancy prior to first annual repeat screening, compared with a possibly optimal work-up of larger nodules...
  23. ncbi Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up
    Dong Ming Xu
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, Postbus 30 001, 9700 RB Groningen, The Netherlands
    Radiology 250:264-72. 2009
    ....
  24. ncbi Clinical practice. The solitary pulmonary nodule
    David Ost
    Center for Pulmonary and Critical Care Medicine, North Shore University Hospital, Manhasset, NY 11030, USA
    N Engl J Med 348:2535-42. 2003
  25. pmc Computer-aided diagnosis of pulmonary nodules on CT scans: segmentation and classification using 3D active contours
    Ted W Way
    Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Med Phys 33:2323-37. 2006
    ..The lung nodule volumes segmented by the 3D AC model for best classification were generally larger than those outlined by the LIDC radiologists using visual judgment of nodule boundaries...
  26. ncbi Predictive CT findings of malignancy in ground-glass nodules on thin-section chest CT: the effects on radiologist performance
    Hyun Ju Lee
    Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Jongno gu, Seoul, Korea
    Eur Radiol 19:552-60. 2009
    ..727 +/- 0.064 and 0.764 +/- 0.056, P > 0.05). Information about lesion size and morphological characteristics can enhance radiologists' performance in determining malignancy of pure GGNs...
  27. ncbi Computer-aided detection and automated CT volumetry of pulmonary nodules
    Katharina Marten
    Department of Radiology, Klinikum rechts der Isar, Technical University Munich, Ismaningerstr 22, 81675, Munich, Germany
    Eur Radiol 17:888-901. 2007
    ..In this review, we give an overview of current CAD in lung nodule detection and volumetry and discuss their relative merits and limitations...
  28. ncbi Shape-based computer-aided detection of lung nodules in thoracic CT images
    Xujiong Ye
    Medicsight PLC, London W14 8UD, UK
    IEEE Trans Biomed Eng 56:1810-20. 2009
    ..The method's high detection rate, fast computation, and applicability to different imaging conditions and nodule types shows much promise for clinical applications...
  29. ncbi Lung nodule detection in low-dose and thin-slice computed tomography
    A Retico
    Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, Largo Pontecorvo 3, 56127 Pisa, Italy
    Comput Biol Med 38:525-34. 2008
    ..The FROC curve obtained on this data set shows high values of sensitivity to lung nodules (80-85% range) at an acceptable level of false positive findings per patient (10-13 FP/scan)...
  30. ncbi Systematic error in lung nodule volumetry: effect of iterative reconstruction versus filtered back projection at different CT parameters
    Martin J Willemink
    Department of Radiology, Utrecht University Medical Center, HP E01 132, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    AJR Am J Roentgenol 199:1241-6. 2012
    ..We compared nodule volumes measured with iterative reconstruction and FBP at different CT parameters...
  31. ncbi Lung nodule detection on thoracic computed tomography images: preliminary evaluation of a computer-aided diagnosis system
    Metin N Gurcan
    Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 0904, USA
    Med Phys 29:2552-8. 2002
    ..These preliminary results demonstrate the feasibility of our approach to lung nodule detection and FP reduction on CT images...
  32. ncbi Computer-aided differentiation of malignant from benign solitary pulmonary nodules imaged by high-resolution CT
    Shingo Iwano
    Department of Radiology, Nagoya University, School of Medicine, 65 Tsurumai Cho, Shouwa ku, Nagoya 466 8550, Japan
    Comput Med Imaging Graph 32:416-22. 2008
    ..Using discriminant analysis for two thresholds in differentiating malignant from benign states resulted in a sensitivity of 76.9%, a specificity of 80%, a positive predictive value of 78.4%, and a negative predictive value of 78.6%...
  33. ncbi Tissue characterization of solitary pulmonary nodule: comparative study between helical dynamic CT and integrated PET/CT
    Chin A Yi
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Nucl Med 47:443-50. 2006
    ..The purpose of this study was to compare the diagnostic accuracy of helical dynamic (HD) CT (HDCT) and integrated PET/CT for pulmonary nodule characterization...
  34. ncbi Three-dimensional analysis of pulmonary nodules: variability of semiautomated volume measurements between different versions of the same software
    M F Rinaldi
    Radiologia III, Policlinico S Orsola Malpighi, Bologna, Italy
    Radiol Med 115:403-12. 2010
    ..This study was done to evaluate the variability of semiautomated volume measurements of solid pulmonary nodules between two different versions of the same volumetric software...
  35. ncbi Flat panel detector-based volumetric CT: prototype evaluation with volumetry of small artificial nodules in a pulmonary phantom
    Katharina Marten
    Department of Radiology, Klinikum rechts der Isar, Technical University, Munich, Germany
    J Thorac Imaging 19:156-63. 2004
    ..To evaluate amorphous silicone-based flat panel detector volumetric CT (VCT) in volumetric assessment of small nodules in a pulmonary phantom, and to perform comparative experiments with 4-row multislice CT (MSCT)...
  36. ncbi European and North American lung cancer screening experience and implications for pulmonary nodule management
    Arjun Nair
    Department of Radiology, St Georges Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK
    Eur Radiol 21:2445-54. 2011
    ..Several European randomised controlled trials for LDCT are underway. • The trials vary in methodology but most compare LDCT to no screening. • Preliminary results have reinforced existing nodule management concepts...
  37. pmc A computer-aided diagnosis for evaluating lung nodules on chest CT: the current status and perspective
    Jin Mo Goo
    Department of Radiology, Seoul National University College of Medicine and the Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 110 744, Korea
    Korean J Radiol 12:145-55. 2011
    ..Therefore, understanding the current status and limitations of CAD for evaluating lung nodules is essential to effectively apply CAD in clinical practice...
  38. ncbi Computer-aided diagnosis: a shape classification of pulmonary nodules imaged by high-resolution CT
    Shingo Iwano
    Department of Radiology, School of Medicine, Nagoya University, Nagoya, 65 Tsurumai Cho, Shouwa ku, Nagoya 466 8550, Japan
    Comput Med Imaging Graph 29:565-70. 2005
    ..We found that pulmonary nodules with circularity < or =0.75 and second moment < or =0.18 were very likely to reveal lung cancer...
  39. ncbi Transient part-solid nodules detected at screening thin-section CT for lung cancer: comparison with persistent part-solid nodules
    Sang Min Lee
    Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center, 101 Daehangno, Jongno gu, Seoul 110 744, Korea
    Radiology 255:242-51. 2010
    ....
  40. ncbi Frequency and significance of pulmonary nodules on thin-section CT in patients with extrapulmonary malignant neoplasms
    Mai Hanamiya
    Department of Radiology, University of Occupational and Environmental Health School of Medicine, Iseigaoka 1 1, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Eur J Radiol 81:152-7. 2012
    ..To determine the frequency and significance of pulmonary nodules detected on thin-section CT in patients with extrapulmonary malignant neoplasms...
  41. ncbi Computer-aided diagnosis of the solitary pulmonary nodule
    Sumit K Shah
    Department of Radiology, David Geffen School of Medicine at University of California Los Angeles, Thoracic Imaging Research Group, 924 Westwood Blvd, Suite 650, Box 957319, Los Angeles, CA 90095 7319, USA
    Acad Radiol 12:570-5. 2005
    ..We sought to investigate the utility of a computer-aided diagnosis in the task of differentiating malignant nodules from benign nodules based on single thin-section computed tomography image data...
  42. ncbi Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions: a meta-analysis
    M K Gould
    Pulmonary Section 111P, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA
    JAMA 285:914-24. 2001
    ..Focal pulmonary lesions are commonly encountered in clinical practice, and positron emission tomography (PET) with the glucose analog 18-fluorodeoxyglucose (FDG) may be an accurate test for identifying malignant lesions...
  43. ncbi Perifissural nodules seen at CT screening for lung cancer
    Myeong I Ahn
    Department of Radiology, Vancouver General Hospital, 899 W 12th Ave, Vancouver, BC, Canada V5Z 1M9
    Radiology 254:949-56. 2010
    ..To describe and characterize the potential for malignancy of noncalcified lung nodules adjacent to fissures that are often found in current or former heavy smokers who undergo computed tomography (CT) for lung cancer screening...
  44. ncbi [Multidetector-row CT of the lungs: Multiplanar reconstructions and maximum intensity projections for the detection of pulmonary nodules]
    R Eibel
    Institut fur Klinische Radiologie, Klinikum Grosshadern derLudwig Maximilians Universität München
    Rofo 173:815-21. 2001
    ....
  45. ncbi Autonomous detection of pulmonary nodules on CT images with a neural network-based fuzzy system
    Daw Tung Lin
    Department of Computer Science and Information Engineering, National Taipei University, 151, University Road, San Shia, Taipei, Taiwan 237, ROC
    Comput Med Imaging Graph 29:447-58. 2005
    ..The proposed system is fully automated with fast processing speed. The studies have shown a high potential for implementation of this system in clinical practice as a CAD tool...
  46. pmc Variability of semiautomated lung nodule volumetry on ultralow-dose CT: comparison with nodule volumetry on standard-dose CT
    Patrick A Hein
    Department of Radiology, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    J Digit Imaging 23:8-17. 2010
    ..Thus, the evaluated segmentation software provides nodule volumetry that appears to be independent of the dose level with which the CT source dataset is acquired...
  47. ncbi Comparison of radiologist and CAD performance in the detection of CT-confirmed subtle pulmonary nodules on digital chest radiographs
    Thorsten Alexander Bley
    Department of Diagnostic Radiology, University Hospital Freiburg, Freiburg, Germany
    Invest Radiol 43:343-8. 2008
    ..Detection of subtle pulmonary nodules on digital radiography is a challenging task for radiologists. The aim of this study was to evaluate the performance of a newly approved computer aided detection (CAD) system...
  48. ncbi Evaluation of a real-time interactive pulmonary nodule analysis system on chest digital radiographic images: a prospective study
    Edwin J R van Beek
    Department of Radiology, Carver College of Medicine, University of Iowa, C751 GH, 200 Hawkins Drive, Iowa City, IA 52242 1077, USA
    Acad Radiol 15:571-5. 2008
    ..We sought to assess the performance of a real-time interactive pulmonary nodule analysis system for evaluation of chest digital radiographic (DR) images in a routine clinical environment...
  49. ncbi Pulmonary nodules: effect of adaptive statistical iterative reconstruction (ASIR) technique on performance of a computer-aided detection (CAD) system-comparison of performance between different-dose CT scans
    Masahiro Yanagawa
    Department of Radiology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita City, Osaka 565 0871, Japan
    Eur J Radiol 81:2877-86. 2012
    ..To evaluate the effects of ASIR on CAD system of pulmonary nodules using clinical routine-dose CT and lower-dose CT...
  50. ncbi Solitary pulmonary nodules in patients with extrapulmonary neoplasms
    L E Quint
    Departments of Radiology and Surgery, Section of Thoracic Surgery, University of Michigan Health Systems, 1500 E Medical Center Dr, Box 0300, Ann Arbor, MI 48109 0030, USA
    Radiology 217:257-61. 2000
    ..To determine the frequency of single lung metastasis, primary lung cancer, and benign lesions in patients with a solitary lung nodule and a primary extrapulmonary neoplasm...
  51. pmc Volumetric measurements of lung nodules with multi-detector row CT: effect of changes in lung volume
    Jin Mo Goo
    Department of Radiology, Seoul National University College of Medicine, and the Institute of Radiation Medicine, SNUMRC, Jongno gu, Seoul, Korea
    Korean J Radiol 7:243-8. 2006
    ..To evaluate how changes in lung volume affect volumetric measurements of lung nodules using a multi-detector row CT...
  52. ncbi Comparison of sensitivity and reading time for the use of computer-aided detection (CAD) of pulmonary nodules at MDCT as concurrent or second reader
    F Beyer
    Department of Clinical Radiology, University Hospital Muenster, Albert Schweitzer Str 33, 48129, Muenster, Germany
    Eur Radiol 17:2941-7. 2007
    ..001). In our study CAD could either speed up reading of chest CT cases for pulmonary nodules without relevant loss of sensitivity when used as CR, or it increased sensitivity at the cost of longer reading times when used as SR...
  53. pmc Evaluation of lung MDCT nodule annotation across radiologists and methods
    Charles R Meyer
    Department of Radiology, School of Medicine, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48109 2200, USA
    Acad Radiol 13:1254-65. 2006
    ..Thus assessing the source of variability in defining the spatial location of lung nodules by expert radiologists using different software tools as an alternative form of truth is necessary...
  54. pmc Solitary pulmonary nodule on helical dynamic CT scans: analysis of the enhancement patterns using a computer-aided diagnosis (CAD) system
    Eun Jung Choi
    Department of Radiology, Chonbuk National University Hospital and Medical School, Research Institute for Medical Science, Chonbuk, Korea
    Korean J Radiol 9:401-8. 2008
    ..We wanted to investigate the usefulness of a computer-aided diagnosis (CAD) system in assisting radiologists to diagnosis malignant solitary pulmonary nodules (SPNs), as compared with diagnosing SPNs with using direct personal drawing...
  55. ncbi Pulmonary nodule volumetric measurement variability as a function of CT slice thickness and nodule morphology
    Myria Petrou
    Department of Radiology, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA
    AJR Am J Roentgenol 188:306-12. 2007
    ....
  56. pmc Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably
    H Ashraf
    Department of Radiology, Gentofte Hospital, Copenhagen University, Hellerup, Denmark
    Eur Radiol 20:1878-85. 2010
    ..We examined the reproducibility of lung nodule volumetry software that offers three different volumetry algorithms...
  57. ncbi Volumetric measurement of synthetic lung nodules with multi-detector row CT: effect of various image reconstruction parameters and segmentation thresholds on measurement accuracy
    Jin Mo Goo
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110, USA
    Radiology 235:850-6. 2005
    ..To evaluate the effect of various multi-detector row computed tomographic (CT) reconstruction parameters and nodule segmentation thresholds on the accuracy of volumetric measurement of synthetic lung nodules...
  58. ncbi Morphological segmentation and partial volume analysis for volumetry of solid pulmonary lesions in thoracic CT scans
    Jan Martin Kuhnigk
    MeVis Center for Medical Visualization and Diagnostic Systems, Universitaetsallee 29, Bremen 28359, Germany
    IEEE Trans Med Imaging 25:417-34. 2006
    ..The method was especially successful in accounting for slice thickness and reconstruction kernel variations, where the median error was more than halved in comparison to the conventional approach...
  59. pmc The Lung Image Database Consortium (LIDC): a comparison of different size metrics for pulmonary nodule measurements
    Anthony P Reeves
    School of Electrical and Computer Engineering, Rhodes Hall, Cornell University, Ithaca, NY 14853, USA
    Acad Radiol 14:1475-85. 2007
    ....
  60. ncbi The solitary pulmonary nodule
    Johnsey L Leef
    Department of Radiology, Fletcher Allen Health Care, and University of Vermont College of Medicine, Burlington 05401, USA
    Radiol Clin North Am 40:123-43, ix. 2002
    ..If the use of low-dose helical CT for screening for early lung cancer in the form of a SPN becomes widespread practice, it is likely that radiologists will encounter an increasing number of smaller SPNs in the near future...
  61. ncbi Evaluation of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition)
    Michael K Gould
    VA Palo Alto Health Care System, 3801 Miranda Ave 111P, Palo Alto, CA 94304, USA
    Chest 132:108S-130S. 2007
    ..Nodules are extremely common in clinical practice and challenging to manage, especially small, "subcentimeter" nodules. Identification of malignant nodules is important because they represent a potentially curable form of lung cancer...
  62. ncbi Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners
    Marco Das
    Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52072 Aachen, Germany
    Eur Radiol 17:1979-84. 2007
    ..Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies...
  63. ncbi The performance of( 18)F-fluorodeoxyglucose positron emission tomography in small solitary pulmonary nodules
    Gerarda J Herder
    Department of Pulmonary Diseases, VU University Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Eur J Nucl Med Mol Imaging 31:1231-6. 2004
    ..Such results may help in the design of larger prospective trials with structured clinical work-up...
  64. ncbi Computer-aided volumetry of pulmonary nodules exhibiting ground-glass opacity at MDCT
    Seitaro Oda
    Department of Diagnostic Radiology, Kumamoto University, Japan
    AJR Am J Roentgenol 194:398-406. 2010
    ..The purpose of this study was to investigate the accuracy and reproducibility of results acquired with computer-aided volumetry software during MDCT of pulmonary nodules exhibiting ground-glass opacity...
  65. ncbi Video-assisted thoracoscopic surgery for small indeterminate pulmonary nodules: indications for preoperative marking
    K Suzuki
    Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan
    Chest 115:563-8. 1999
    ..To determine the indications for preoperative localization of a small indeterminate pulmonary nodule...
  66. ncbi Prospective investigation of positron emission tomography in lung nodules
    V J Lowe
    Department of Nuclear Medicine, St Louis University Health Sciences Center, Mo 63110 0250, USA
    J Clin Oncol 16:1075-84. 1998
    ..We evaluated the ability of fluorine-18 deoxyglucose positron emission tomography (FDG-PET) to discriminate between benign and malignant pulmonary nodules in a prospective, multicenter trial...
  67. ncbi Computer-aided detection of solid lung nodules on follow-up MDCT screening: evaluation of detection, tracking, and reading time
    Catherine Beigelman-Aubry
    Department of Radiology, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, University Pierre et Marie Curie, Paris VI, 47 83 Bd de l Hopital, 75651 Paris, Cedex 13, France
    AJR Am J Roentgenol 189:948-55. 2007
    ..The purpose of this article is to assess detection, tracking, and reading time of solid lung nodules > or = 4 mm on pairs of MDCT chest screening examinations using a computer-aided detection (CAD) system...
  68. ncbi Indeterminate solitary pulmonary nodules revealed at population-based CT screening of the lung: using first follow-up diagnostic CT to differentiate benign and malignant lesions
    Shodayu Takashima
    Department of Radiology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    AJR Am J Roentgenol 180:1255-63. 2003
    ....
  69. ncbi Persistent pure ground-glass nodules in the lung: interscan variability of semiautomated volume and attenuation measurements
    Chang Min Park
    Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center, 101 Daehangno, Jongno gu, Seoul 110 744, Republic of Korea
    AJR Am J Roentgenol 195:W408-14. 2010
    ..The purpose of this article is to assess the interscan variability of semiautomated volume and attenuation measurements for pulmonary persistent pure ground-glass nodules...
  70. ncbi Pulmonary nodules detected at lung cancer screening: interobserver variability of semiautomated volume measurements
    Hester A Gietema
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 241:251-7. 2006
    ..To retrospectively determine interobserver variability of semiautomated volume measurements of pulmonary nodules and the potential reasons for variability...
  71. ncbi Managing the small pulmonary nodule discovered by CT
    Daniel M Libby
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Weill Medical College of Cornell University, New York, NY, USA
    Chest 125:1522-9. 2004
    ..To review the Early Lung Cancer Action Project experience and the medical literature from 1993 to 2003 on detection of the small, noncalcified pulmonary nodule by CT in order to formulate a management algorithm for these nodules...
  72. ncbi Incremental benefit of maximum-intensity-projection images on observer detection of small pulmonary nodules revealed by multidetector CT
    James F Gruden
    Division of Cardiothoracic Imaging, Image Processing Laboratory, Emory University Hospital and Clinic, 1324 Clifton Road N E, Ste E 118, Atlanta, GA 30322, USA
    AJR Am J Roentgenol 179:149-57. 2002
    ....
  73. ncbi Pulmonary perifissural nodules on CT scans: rapid growth is not a predictor of malignancy
    Bartjan de Hoop
    Department of Radiology, Rijnstate Hospital, Wagnerlaan 55, 6815 AD, Arnhem, The Netherlands
    Radiology 265:611-6. 2012
    ..To assess the prevalence, natural course, and malignancy rate of perifissural nodules (PFNs) in smokers participating in a lung cancer screening trial...
  74. pmc Computerized detection of lung nodules in thin-section CT images by use of selective enhancement filters and an automated rule-based classifier
    Qiang Li
    Department of Radiology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Acad Radiol 15:165-75. 2008
    ..We have been developing a computer-aided diagnostic (CAD) scheme for lung nodule detection in order to assist radiologists in the detection of lung cancer in thin-section computed tomography (CT) images...
  75. ncbi 18-fluorine fluorodeoxyglucose positron emission tomography with computerized tomography versus computerized tomography alone for the management of solitary lung nodules with diameters inferior to 1.5 cm
    D Divisi
    Department of Thoracic Surgery, University of L Aquila, Teramo, Italy
    Thorac Cardiovasc Surg 58:422-6. 2010
    ..Aim of the study was to establish a noninvasive method for the preoperative characterisation of a pulmonary nodule when biopsy of the small mass is impossible...
  76. ncbi CT-guided hook wire localization of subpleural lung lesions for video-assisted thoracoscopic surgery (VATS)
    Yu Ruei Chen
    Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Taipei, Taiwan
    J Formos Med Assoc 106:911-8. 2007
    ..This study reviewed the indications, results and complications of CT-guided hook wire localization for subpleural lung lesions in video-assisted thoracoscopic surgery (VATS)...
  77. ncbi Pulmonary nodules: detection, assessment, and CAD
    Francis Girvin
    Department of Radiology, Thoracic Imaging, New York University Medical Center, 560 1st Ave, New York, NY 10016, USA
    AJR Am J Roentgenol 191:1057-69. 2008
    ..The potential contribution of MRI, evolving imaging-guided techniques, and computer applications are also discussed...
  78. ncbi Marking of small pulmonary nodules before thoracoscopic resection: injection of lipiodol under CT-fluoroscopic guidance
    Koichi Kawanaka
    Department of Diagnostic Radiology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan
    Acad Radiol 16:39-45. 2009
    ..The aim of the present study was to examine the usefulness and record the complications of preoperative lipiodol marking using computed tomographic (CT) fluoroscopy for the intraoperative localization of 107 pulmonary nodules...
  79. ncbi Linear and volume measurements of pulmonary nodules at different CT dose levels - intrascan and interscan analysis
    P A Hein
    Institut fur Radiologie, Charite Campus Mitte, Charite Universitatsmedizin Berlin
    Rofo 181:24-31. 2009
    ....
  80. ncbi The value of FDG-PET/CT in assessing single pulmonary nodules in patients at high risk of lung cancer
    Olga Kagna
    Department of Nuclear Medicine, Ramban Health Care Campus, Technion, Israel Institute of Technology, Haifa, Israel
    Eur J Nucl Med Mol Imaging 36:997-1004. 2009
    ..To evaluate whether PET/low-dose CT (ldCT) using (18)F-fluorodeoxyglucose (FDG) improves characterization of indeterminate single pulmonary nodules (SPNs) in patients at high risk of lung cancer...
  81. ncbi Video-assisted thoracoscopic solitary pulmonary nodule resection after CT-guided hookwire localization: 43 cases report and literature review
    Sufeng Chen
    Department of Thoracic Surgery, Cancer Hospital of Fudan University, Shanghai, China
    Surg Endosc 25:1723-9. 2011
    ....
  82. ncbi Percutaneous localisation of pulmonary nodules prior to video-assisted thoracoscopic surgery using methylene blue and TC-99
    Yi Zarn Wang
    Louisiana State University, Department of Surgery, New Orleans, LA 70112, USA
    Eur J Cardiothorac Surg 37:237-8. 2010
    ..This modified dual agent's preoperative localisation is logical, practical and easy to be adopted into the clinical setting for surgeons who choose to use the VATS technique in addressing these lung nodules...
  83. ncbi The pulmonary nodule: clinical and radiological characteristics affecting a diagnosis of malignancy
    L Cardinale
    S C D U Radiologia, Ospedale San Luigi Gonzaga, Regione Gonzole 10, Orbassano, Torino, Italy
    Radiol Med 114:871-89. 2009
    ..The aim of this paper is to summarise the approach to pulmonary nodules from the point of view of the radiologist, oncologist and thoracic surgeon...
  84. ncbi Fluoroscopy-aided thoracoscopic resection of pulmonary nodule localized with contrast media
    S W Moon
    Department of Thoracic and Cardiovascular Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Ann Thorac Surg 68:1815-20. 1999
    ..Recently, several preoperative or intraoperative techniques for identifying small or deeply seated pulmonary nodules have facilitated thoracoscopic resection. We describe the new technique for detecting difficult lesions...
  85. ncbi Thoracoscopic resection of pulmonary nodules after computed tomographic-guided coil labeling
    N Lizza
    Department of Cardiovascular and Thoracic Surgery, University of Louvain Medical School at Mont-Godinne University Hospital, Yvoir, Belgium
    Ann Thorac Surg 71:986-8. 2001
    ..CONCLUSIONS: Our experience with microcoil injection shows that it provides consistent and highly accurate marking of pulmonary nodules for video-assisted thoracic surgery, allowing secure resection with a safe margin...
  86. pmc A resource for the assessment of lung nodule size estimation methods: database of thoracic CT scans of an anthropomorphic phantom
    Marios A Gavrielides
    Division of Imaging and Mathematics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U S Food and Drug Administration, Silver Spring, MD, USA
    Opt Express 18:15244-55. 2010
    ..This resource complements public databases of clinical data and will contribute towards the development of procedures that will maximize the utility of CT imaging for lung cancer screening and tumor therapy evaluation...
  87. ncbi Positron emission tomography imaging in nonmalignant thoracic disorders
    Abass Alavi
    Division of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Semin Nucl Med 32:293-321. 2002
    ..Finally, the value of FDG-PET in differentiating benign from malignant diseases of the pleura including asbestosis-related disorders is described at the conclusion of this comprehensive review...
  88. ncbi Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules
    Nicolas Kahn
    Department of Thoracic Surgery, Thoraxklinik, University of Heidelberg, Germany
    J Thorac Cardiovasc Surg 138:474-9. 2009
    ..We investigated the feasibility of bronchoscopic microsampling to collect endobronchial epithelial lining fluid to obtain RNA as a starting point for gene expression profiling...
  89. ncbi Can lung cancer screening by computed tomography be effective in areas with endemic histoplasmosis?
    Sandra L Starnes
    Division of Thoracic Surgery, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Thorac Cardiovasc Surg 141:688-93. 2011
    ..The goal of the present study was to determine whether lung cancer screening could be done while minimizing the number of benign biopsy specimens taken in an area endemic for histoplasmosis...
  90. ncbi The role of surgery in the management of solitary pulmonary nodule in breast cancer patients
    O Rena
    Thoracic Surgery Department, University A Avogadro, Via Frasconi, 14, 28100 Novara, Italy
    Eur J Surg Oncol 33:546-50. 2007
    ..To assess the role of surgery in the diagnosis and treatment of a solitary pulmonary nodule (SPN) in patients who had received previous surgery for breast cancer...
  91. ncbi Model-based detection of lung nodules in computed tomography exams. Thoracic computer-aided diagnosis
    Colin C McCulloch
    Applied Statistics Laboratory, GE Global Research Center, Building K1, Room 4C29A, One Research Circle, Niskayuna, NY 12309, USA
    Acad Radiol 11:258-66. 2004
    ..By using this CAD algorithm, along with the radiologist's initial interpretation, we aim to improve the sensitivity of radiologic readings of CT lung exams...
  92. ncbi Automated matching of pulmonary nodules: evaluation in serial screening chest CT
    Cheng Tao
    Department of Radiology, University of Pittsburgh School of Medicine, 3362 Fifth Ave, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 192:624-8. 2009
    ..The purpose of our study was to evaluate the performance of a computer-aided program that performs automated matching of pulmonary nodules imaged in three serial screening chest MDCT studies...
  93. ncbi Performance of a computer-aided program for automated matching of metastatic pulmonary nodules detected on follow-up chest CT
    Kyung Won Lee
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA
    AJR Am J Roentgenol 189:1077-81. 2007
    ..The purpose of this study was to evaluate the performance of a computer-aided program that allows automated matching of metastatic pulmonary nodules imaged with two serial clinical chest CT studies...
  94. ncbi Efficacy of computer-aided detection system and thin-slab maximum intensity projection technique in the detection of pulmonary nodules in patients with resected metastases
    Eun Ah Park
    Department of Radiology, Seoul National University College of Medicine, Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea
    Invest Radiol 44:105-13. 2009
    ....
  95. pmc Effect of CAD on radiologists' detection of lung nodules on thoracic CT scans: analysis of an observer performance study by nodule size
    Berkman Sahiner
    Department of Radiology, The University of Michigan, MIB C480A, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Acad Radiol 16:1518-30. 2009
    ....
  96. ncbi Role of video-assisted thoracic surgery for the diagnosis of indeterminate pulmonary nodule
    Shinji Hirai
    Department of Thoracic and Cardiovascular Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan
    Ann Thorac Cardiovasc Surg 12:388-92. 2006
    ..A study was undertaken to evaluate the validity and efficacy of video-assisted thoracic surgery (VATS) for the diagnosis of indeterminate pulmonary nodules...
  97. ncbi Evaluation of computer-aided diagnosis (CAD) software for the detection of lung nodules on multidetector row computed tomography (MDCT): JAFROC study for the improvement in radiologists' diagnostic accuracy
    Tomohiro Hirose
    Department of Radiology, Shiga University of Medical Science, Seta tsukinowa cho, Otsu shi, Shiga 520 2192, Japan
    Acad Radiol 15:1505-12. 2008
    ....
  98. ncbi Solitary pulmonary nodules: morphological and metabolic characterisation by FDG-PET-MDCT
    A Orlacchio
    Dipartimento di Diagnostica per Immagini e Radiologia Interventistica, Policlinico Universitario Tor Vergata, Viale Oxford 81, I 00133, Roma, Italy
    Radiol Med 112:157-73. 2007
    ....
  99. ncbi Computer-assisted lung nodule volumetry from multi-detector row CT: influence of image reconstruction parameters
    Osamu Honda
    Department of Radiology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Eur J Radiol 62:106-13. 2007
    ..To investigate differences in volumetric measurement of pulmonary nodules caused by changing the reconstruction parameters for multi-detector row CT...
  100. ncbi Computer-aided pulmonary nodule detection - performance of two CAD systems at different CT dose levels
    P A Hein
    Institut fur Radiologie, Charite Campus Mitte, Charite Universitatsmedizin Berlin
    Rofo 181:1056-64. 2009
    ....
  101. ncbi Solid or partly solid solitary pulmonary nodules: their characterization using contrast wash-in and morphologic features at helical CT
    Kyung Soo Lee
    Department of Radiology, Samsung Medical Center, 50 Ilwon Dong, Kangnam Ku, Seoul 135 710, Korea
    Chest 131:1516-25. 2007
    ..However, increased specificity results in reduced sensitivity and the missing of malignant SPNs. Thus, the purpose of this study was to seek the most effective method for SPN characterization during HDCT scanning...

Research Grants47

  1. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael K Gould; Fiscal Year: 2011
    ..abstract_text> ..
  2. Ventilator-induced diaphragm dysfunction
    SANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010
    ..Moreover, these studies may directly lead to therapy for this newly recognized but relatively common disease of diaphragm muscle. ..
  3. Thin Film Magnetic Sensors for Ultrathin Bronchoscope Navigation
    Timothy Riehle; Fiscal Year: 2009
    ..Over 3,000,000 bronchoscopies are performed annually worldwide. The majority of target lung lesions are located in the peripheral areas of the lungs where large bronchoscopes cannot reach. ..
  4. Dynamic contrast-enhanced MRI of pulmonary nodule at 3T
    Hiroto Hatabu; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  5. COMPUTER AIDED DIAGNOSIS IN CT OF THE THORAX
    Samuel Armato; Fiscal Year: 2004
    ....
  6. Standard Database for CT Lung Images
    Samuel Armato; Fiscal Year: 2006
    ..The ideas resented in this proposal are expected to stimulate the efforts of the Consortium toward that goal. ..
  7. Computerized Analysis of Mesothelioma on CT Scans
    Samuel Armato; Fiscal Year: 2009
    ....
  8. 3D Massive Training ANN for CAD for Colon Cancer in CT Colonography
    Kenji Suzuki; Fiscal Year: 2010
    ....
  9. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  10. Medical Image Perception Society Confrence XI
    Elizabeth Krupinski; Fiscal Year: 2005
    ..abstract_text> ..
  11. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2003
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  12. Optimized Compression for Telepathology Virtual Slides
    Elizabeth Krupinski; Fiscal Year: 2009
    ....
  13. Conference--Medical Image Perception
    Elizabeth Krupinski; Fiscal Year: 2003
    ..This grant will be used to provide financial support for about 12 graduate students and residents, as well as logistic support for publicity and program printing. ..
  14. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2002
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  15. DIAGNOSIS OF THE SOLITARY PULMONARY NODULE IMAGED ON CT
    MIKE MCNITT GRAY; Fiscal Year: 2003
    ....
  16. Monte Carlo Based Patient Radiation Dose from CT
    Michael McNitt Gray; Fiscal Year: 2008
    ..can be obtained without performing all aspects of the detailed analysis and modeling. [unreadable] [unreadable]..
  17. Lung Imaging Database Resource for Imaging Research
    MIKE MCNITT GRAY; Fiscal Year: 2006
    ..SA-3 To provide a means for documentation and distribution of this database to researchers through the internet. ..
  18. Computer Detection of Nodules of the Lung
    Anthony Reeves; Fiscal Year: 2007
    ..The complete detection system will be evaluated with a CT image database that has a ground truth established by multiple radiologist reads. [unreadable] [unreadable]..
  19. Bi-Plane Correlation Imaging: Detection of Lung Cancer
    Ehsan Samei; Fiscal Year: 2007
    ..The findings will be used to substantiate the capability of BCI for improving the early detection of lung nodules and to optimize its performance on actual clinical cases. ..
  20. Archiving the Charleston Heart Study
    Paul Nietert; Fiscal Year: 2002
    ..abstract_text> ..
  21. Resolution requirements for mammographic displays
    Ehsan Samei; Fiscal Year: 2004
    ..The results will be used to formulate recommendations to the breast imaging community concerning display resolution criteria for safe and optimized soft-copy display of digital mammograms. ..
  22. Early Detection of Lung Cancer via Bi Plane Correlation
    Ehsan Samei; Fiscal Year: 2002
    ..The findings will be used to demonstrate the capability of the approach for improving the detection of lung nodules, and thus the prognosis of lung cancer. ..
  23. International Conferences on Screening for Lung Cancer
    Claudia Henschke; Fiscal Year: 2003
    ..The advantage of such a consensus reports is that it will provide useful and up-to-date information about CT screening on which to base the national and international policies in a very timely and cost-efficient manner. ..
  24. Exploration of Stereo Display for Lung Cancer Screening
    Xiao Hui Wang; Fiscal Year: 2005
    ..We expect to demonstrate that the use of a stereo display for lung cancer screening will result in improved accuracy and efficiency, and this could greatly increase the efficacy of this screening process. ..
  25. PATIENT SPECIFIC MODELS IN LUNG CANCER SCREENING WITH CT
    Matthew Brown; Fiscal Year: 2004
    ..4] To compare radiologist accuracy and interpretation times of HR-hCT scans, both with and without assistance from the automated detection system, against pre-existing nodule detection methods. ..
  26. Growth Assessment of Pulmonary Nodules
    David Yankelevitz; Fiscal Year: 2007
    ..The innovations we propose to address in this grant application will markedly enhance the applicability of ERCT in a more diverse, non-research, clinical setting. ..
  27. PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATION
    Dev Chakraborty; Fiscal Year: 2003
    ..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
  28. CAD for CT Nodules in Lung Cancer Detection
    Kunio Doi; Fiscal Year: 2006
    ..abstract_text> ..
  29. Computerized Classification of COPD and Contributing Components
    Joseph K Leader; Fiscal Year: 2010
    ..If successful, the proposal will result in advanced methods to characterize pulmonary disease in the individual patient and to monitor the effectiveness of treatment as well. ..
  30. Discovery of Biomarkers for Lung Cancer Metastasis
    Edward Patz; Fiscal Year: 2009
    ..This translational project will focus on an essential prognostic issue in lung cancer, but this model can be applied to any other diagnostic question in oncology. ..
  31. COMPUTER AIDED DIAGNOSIS IN CHEST RADIOGRAPHY
    Kunio Doi; Fiscal Year: 2004
    ....
  32. PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATION
    Dev Chakraborty; Fiscal Year: 2002
    ..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
  33. Alveolitis and Fibrosis in Scleroderma Lung Disease
    Jonathan Goldin; Fiscal Year: 2004
    ..These findings will potentially improve our understanding of the relationship between alveolitis and fibrosis and to the pathogenesis of fibrosis in SLD. ..
  34. Imaging of Pulmonary Cancer: Overcoming Limitations
    Jane Ko; Fiscal Year: 2007
    ..The proposed method will enable early recognition of nodule growth and, therefore, the early diagnosis of malignancy. ..
  35. Development and CAD Assessment of a PN Database
    David Yankelevitz; Fiscal Year: 2006
    ..Working groups will include radiology, CAD development, and informatics and our outreach efforts will include patient advocacy and early users of the database. ..
  36. THE ROLE OF A BONE MORPHOGENETIC PROTEIN IN LUNG CANCER
    John Langenfeld; Fiscal Year: 2004
    ..Our long-term goal is to use BMP-2 inhibiting therapy as a modality to prevent the progression of lung cancer. ..
  37. Phase Contrast Computed Tomography Scanner
    Edwin Donnelly; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  38. Monochromatic Phase-Contrast Breast Cancer Radiography
    Edwin Donnelly; Fiscal Year: 2005
    ..Image quality of all images will be judged by an experienced mammographer. ..
  39. Promotion of Angiogenesis in Lung Cancer by MIF
    Douglas A Arenberg; Fiscal Year: 2010
    ..Specific aim: a) Determine the role of CD74 in the promotion of lung tumor growth by MIF, and b) to determine the role myeloid cells in the MIF-CD74 axis in lung cancer. ..
  40. Lung Image Database
    Charles Meyer; Fiscal Year: 2006
    ..4) The Department of Radiology and the University Hospitals are already committed to the acquisition of new generation CT and PET scanners within the next 2 years. ..
  41. Multimodality CAD system with image references for breast mass characterization
    Berkman Sahiner; Fiscal Year: 2007
    ..Any reduction in this number without a decrease in breast cancer detection sensitivity will decrease health care costs, as well as contribute to the well-being of the patient by reducing anxiety and morbidity. ..
  42. Computer Asistance for Targeting of Small Pulmonary Nodules in CT-Guided Biopsy
    David Yankelevitz; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  43. Diagnosis and prognosis of lung cancer using gene ratios
    GAVIN GORDON; Fiscal Year: 2004
    ..Specific Aim 4. To develop software for the expression ratio test and to design a form summarizing the results of the diagnostic test kit to clinicians and health care personnel. ..