opisthorchiasis

Summary

Summary: Infection with flukes of the genus Opisthorchis.

Top Publications

  1. ncbi A case of Opisthorchis felineus infestation in a pilot from Greece
    E Tselepatiotis
    Dept of Internal Medicine, Patission General Hospital, Athens, Greece
    Infection 31:430-2. 2003
  2. ncbi Development and evaluation of a polymerase chain reaction (PCR) assay for the detection of Opisthorchis viverrini in fish
    Ammini Parvathi
    Department of Fishery Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences University, College of Fisheries, Mangalore 575 002, India
    Acta Trop 107:13-6. 2008
  3. pmc The current status of opisthorchiasis and clonorchiasis in the Mekong Basin
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:10-6. 2012
  4. ncbi Taxonomy and biology of liver flukes
    Sasithorn Kaewkes
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:177-86. 2003
  5. ncbi Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR
    Somphou Sayasone
    Institut de la Francophonie pour la Médecine Tropicale, Vientiane, Lao PDR
    Trans R Soc Trop Med Hyg 101:40-7. 2007
  6. ncbi Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100)
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    World J Gastroenterol 11:3392-7. 2005
  7. pmc Cholangiocarcinoma: lessons from Thailand
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Thailand
    Curr Opin Gastroenterol 24:349-56. 2008
  8. ncbi Opisthorchiasis control in Thailand
    P Jongsuksuntigul
    Department of Disease Control, Ministry of Public Health, Tiwanon Road, Nonthaburi 11000, Thailand
    Acta Trop 88:229-32. 2003
  9. ncbi Local perceptions and practices in regard to opisthorchiasis in two villages in Lao PDR
    Hanne Strandgaard
    DBL Center for Health Research and Development, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Charlottenlund, Denmark
    Southeast Asian J Trop Med Public Health 39:19-26. 2008
  10. ncbi Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand
    Satoshi Honjo
    Epidemiology Unit, Research Institute, Tochigi Cancer Centre, Utsunomiya, Japan
    Int J Cancer 117:854-60. 2005

Scientific Experts

Detail Information

Publications175 found, 100 shown here

  1. ncbi A case of Opisthorchis felineus infestation in a pilot from Greece
    E Tselepatiotis
    Dept of Internal Medicine, Patission General Hospital, Athens, Greece
    Infection 31:430-2. 2003
    ..He was successfully treated with praziquantel administered in divided doses over a single day. Opisthorchiasis is common to eastern Europe and areas of the former Soviet Union, but extremely rare in Greece...
  2. ncbi Development and evaluation of a polymerase chain reaction (PCR) assay for the detection of Opisthorchis viverrini in fish
    Ammini Parvathi
    Department of Fishery Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences University, College of Fisheries, Mangalore 575 002, India
    Acta Trop 107:13-6. 2008
    ..viverrini. Owing to potential risk of transmission of opisthorchiasis through fish trade, rapid and reliable detection methods have gained importance to ensure food safety...
  3. pmc The current status of opisthorchiasis and clonorchiasis in the Mekong Basin
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:10-6. 2012
    ..Updated data on prevalence and distribution have been summarized from presentations in the "96 Years of Opisthorchiasis. International Congress of Liver Flukes"...
  4. ncbi Taxonomy and biology of liver flukes
    Sasithorn Kaewkes
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:177-86. 2003
    ..However, the differentiation between opisthorchid and lecithodendrid eggs is possible. Morphology and biology of each stage are comparatively reviewed. Biological aspects of snail and fish hosts are also included...
  5. ncbi Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR
    Somphou Sayasone
    Institut de la Francophonie pour la Médecine Tropicale, Vientiane, Lao PDR
    Trans R Soc Trop Med Hyg 101:40-7. 2007
    ..The disease associated with O. viverrini infection needs to be assessed in order to develop and conduct adequate interventions...
  6. ncbi Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100)
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    World J Gastroenterol 11:3392-7. 2005
    ..To establish and characterize a new cholangiocarcinoma cell line from a patient living in the Opisthorchis viverrini (O. viverrini) endemic area of Northeast Thailand...
  7. pmc Cholangiocarcinoma: lessons from Thailand
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Thailand
    Curr Opin Gastroenterol 24:349-56. 2008
    ..To present the background of liver fluke-associated cholangiocarcinoma in Thailand focusing on recent epidemiological data and pathogenesis of this bile duct cancer...
  8. ncbi Opisthorchiasis control in Thailand
    P Jongsuksuntigul
    Department of Disease Control, Ministry of Public Health, Tiwanon Road, Nonthaburi 11000, Thailand
    Acta Trop 88:229-32. 2003
    History of opisthorchiasis control started in 1950 as a small scale helminthiasis control program in some high risk areas...
  9. ncbi Local perceptions and practices in regard to opisthorchiasis in two villages in Lao PDR
    Hanne Strandgaard
    DBL Center for Health Research and Development, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Charlottenlund, Denmark
    Southeast Asian J Trop Med Public Health 39:19-26. 2008
    The aim of the present study was to assess local perceptions and practices in regard to opisthorchiasis in a village receiving treatment and health education compared to a village where no intervention was offered...
  10. ncbi Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand
    Satoshi Honjo
    Epidemiology Unit, Research Institute, Tochigi Cancer Centre, Utsunomiya, Japan
    Int J Cancer 117:854-60. 2005
    ..Infection with OV correlates strongly with cholangiocarcinoma, susceptibility to which may be possibly associated with GSTM1 polymorphism. Alcohol may affect metabolic pathways of endogenous and exogenous nitrosamines...
  11. ncbi Epidemiology of Opisthorchis viverrini
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:187-94. 2003
    ..In this review, we present the basic population features and the factors influencing transmission between the different hosts...
  12. ncbi High prevalence of Opisthorchis viverrini infection in reservoir hosts in four districts of Khon Kaen Province, an opisthorchiasis endemic area of Thailand
    Surasit Aunpromma
    Department of Veterinary Pathobiology, Faculty of Veterinary Medicine, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:60-4. 2012
    Khon Kaen, a northeastern province of Thailand, has been considered as one of the human opisthorchiasis endemic areas with continuing high prevalence...
  13. ncbi Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis
    Somchai Pinlaor
    Department of Environmental and Molecular Medicine, Mie University School of Medicine, Mie 514 8507, Japan
    Nitric Oxide 11:175-83. 2004
    ..In conclusion, nitrative and oxidative DNA damage via iNOS expression in hamsters infected with OV may participate in CHCA carcinogenesis...
  14. ncbi Update on hepatobiliary flukes: fascioliasis, opisthorchiasis and clonorchiasis
    Luis A Marcos
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Curr Opin Infect Dis 21:523-30. 2008
    ..The present review focuses on current knowledge of clinical, diagnostic and treatment aspects caused by hepatobiliary flukes that can be applied to current protocols in endemic areas...
  15. pmc Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis
    Jittiyawadee Sripa
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:191-5. 2012
    ..viverrini cathepsin B1 (rOv-CB-1) as an antigen for immunodiagnosis of opisthorchiasis. The full length Ov-CB-1 cDNA was cloned and recombinant protein was produced in catalytically active form in ..
  16. ncbi Raw attitudes, wetland cultures, life-cycles: socio-cultural dynamics relating to Opisthorchis viverrini in the Mekong Basin
    Carl Grundy-Warr
    Department of Geography, National University of Singapore, 21 Lower Kent Ridge Road, Singapore 119077, Singapore
    Parasitol Int 61:65-70. 2012
    ..food cultures based on eating raw, semi-cooked and fermented fish dishes, which are known to lead to opisthorchiasis, and potentially cholangiocarcinoma...
  17. ncbi Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis
    Prajak Sawangsoda
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Parasitol Int 61:196-202. 2012
    ..viverrini-specific immunoglobulins in serum, urine and saliva and assessed efficacies in diagnosis of opisthorchiasis and evaluated the relationship of antibodies among clinical specimens in a sample population in endemic areas ..
  18. ncbi An epidemiological study on Opisthorchis viverrini infection in Lao villages
    J Kobayashi
    Department of Parasitology, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan
    Southeast Asian J Trop Med Public Health 31:128-32. 2000
    ..Infection with Opisthorchis viverrini appears to be a serious public health problem strongly associated with the frequent eating habit of raw fish in low land Laos...
  19. pmc Spatial distribution of, and risk factors for, Opisthorchis viverrini infection in southern Lao PDR
    Armelle Forrer
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1481. 2012
    ..Our aim was to map the distribution of O. viverrini in southern Lao PDR, identify underlying risk factors, and predict the prevalence of O. viverrini at non-surveyed locations...
  20. ncbi Time profiles of the expression of metalloproteinases, tissue inhibitors of metalloproteases, cytokines and collagens in hamsters infected with Opisthorchis viverrini with special reference to peribiliary fibrosis and liver injury
    Suksanti Prakobwong
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Int J Parasitol 39:825-35. 2009
    ..MMPs and TIMPs may serve as diagnostic markers for the severity of O. viverrini-induced liver injury...
  21. pmc A new PCR-based approach indicates the range of Clonorchis sinensis now extends to Central Thailand
    Rebecca J Traub
    School of Veterinary Science, University of Queensland, St Lucia, Queensland, Australia
    PLoS Negl Trop Dis 3:e367. 2009
    ..This extends the known range of this liver fluke in Southeast Asia. The PCR developed herein provides an important tool for the specific identification of liver and intestinal fluke species for future epidemiological surveys...
  22. ncbi Liver fluke-associated cholangiocarcinoma
    P Watanapa
    Departments of Surgery and Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10 700, Thailand
    Br J Surg 89:962-70. 2002
    ..Infection with liver flukes has been reported to be associated with bile duct malignancy...
  23. ncbi Discovery of Opisthorchis viverrini metacercariae in freshwater fish in southern Cambodia
    Sarun Touch
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Acta Trop 111:108-13. 2009
    ..The small liver fluke found in this study were identified as Opisthorchis viverrini by the morphological features of adult worms, and this identification was confirmed by partial COI sequencing of the metacercariae...
  24. ncbi Molecular identification and phylogenetic analysis of nuclear rDNA sequences among three opisthorchid liver fluke species (Opisthorchiidae: Trematoda)
    Seokha Kang
    Department of Parasitology and Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    Parasitol Int 57:191-7. 2008
    ..Our data are insufficient for discriminating between sudden cladogenesis and other potential causes of poor resolution. Further information from independent loci might help resolve this phylogeny...
  25. ncbi Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis
    Raynoo Thanan
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Cancer Epidemiol Biomarkers Prev 17:518-24. 2008
    ..Urinary 8-oxodG may be a useful biomarker to monitor not only infection but also carcinogenesis...
  26. pmc Opisthorchiasis from imported raw fish
    Orit Yossepowitch
    E Wolfson Hospital, Holon, Israel
    Emerg Infect Dis 10:2122-6. 2004
    ..We report an outbreak of acute opisthorchiasis in a family that was infected in a non-disease-endemic area after eating raw carp illegally imported from a ..
  27. ncbi A high frequency of hepatobiliary disease and suspected cholangiocarcinoma associated with heavy Opisthorchis viverrini infection in a small community in north-east Thailand
    D B Elkins
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Thailand
    Trans R Soc Trop Med Hyg 84:715-9. 1990
    ..These results indicate that Opisthorchis is associated with moderate to severe hepatobiliary disease in a considerable proportion of infected individuals...
  28. ncbi Opisthorchis viverrini: evaluation of 28 kDa glutathione S-transferase as diagnostic tool in human opisthorchiasis
    Veerachai Eursitthichai
    Graduate Program in Biomedical Sciences, Faculty of Allied Health Sciences, Thammasat University, Rangsit Campus, 99 Moo 18, Pathumthani 12121, Thailand
    Acta Trop 114:76-80. 2010
    The liver fluke Opisthorchis viverrini is the agent of human opisthorchiasis in Thailand with a high prevalence observed in the rural population of north and northeastern regions of the country...
  29. ncbi Nucleotide sequence of mitochondrial CO I and ribosomal ITS II genes of Opisthorchis viverrini in northeast Thailand
    K Ando
    Department of Medical Zoology, School of Medicine, Mie University, Tsu, Japan
    Southeast Asian J Trop Med Public Health 32:17-22. 2001
    ..viverrini ITS II gene (296 bp) from different areas were identical. However, they were different from those of Clonorchis sinensis, Haplorchis taichui, H. pumilio, Fasciola gigantica, Echinostoma malayanum and Centrocestus sp....
  30. ncbi Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos
    J Y Chai
    Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul 110 799, Korea
    J Helminthol 79:283-9. 2005
    ....
  31. ncbi Prevalence of Opisthorchis viverrini infection and incidence of cholangiocarcinoma in Khon Kaen, Northeast Thailand
    S Sriamporn
    Department of Epidemiology, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
    Trop Med Int Health 9:588-94. 2004
    ..The cancer registry is an appropriate tool for disease monitoring in small areas...
  32. pmc Opisthorchiasis in Thailand: review and current status
    Natthawut Kaewpitoon
    Research and Diagnostic Center for Parasitic Infectious Diseases, Northeastern Region RCPNER, College of Medicine and Public Health, Ubon Rajathanee University, Warinchamrap district, Ubonratchathai province 34190, Thailand
    World J Gastroenterol 14:2297-302. 2008
    b>Opisthorchiasis caused by Opisthorchis viverrini (O. viverrini) remains a major public health problem in many parts of Southeast Asia including Thailand, Lao PDR, Vietnam and Cambodia...
  33. pmc Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand
    Eimorn Mairiang
    Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:208-11. 2012
    A cross sectional study on hepatobiliary abnormalities in opisthorchiasis was performed in 8936 males and females aged from 20 to 60 years from 90 villages of Khon Kaen province, Northeast Thailand...
  34. ncbi Immunology and molecular biology of Opisthorchis viverrini infection
    S Wongratanacheewin
    Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Acta Trop 88:195-207. 2003
    b>Opisthorchiasis is the major public health problems in Laos PDR and Thailand. The disease becomes chronic and persists for many years, leading to hepatobiliary disease and cholangiocarcinoma...
  35. pmc Cryptic and asymptomatic Opisthorchis felineus infections
    Orlando Armignacco
    Unita Operativa Complessa Malattie Infettive, Belcolle Hospital, Viterbo, Italy
    Am J Trop Med Hyg 88:364-6. 2013
    We describe the diagnostic difficulties experienced during an opisthorchiasis outbreak. Of 31 infected individuals, 61...
  36. ncbi Impact of temporal changes and host factors on the genetic structure of a population of Opisthorchis viverrini sensu lato in Khon Kaen Province (Thailand)
    W Saijuntha
    Walai Rukhavej Botanical Research Institute WRBRI, Mahasarakham University, Mahasarakham 44150, Thailand
    Parasitology 136:1057-63. 2009
    ..viverrini are discussed in terms of self- and cross-fertilisation, natural selection, non-random mating, the Wahlund effect, presence of null alleles, intensity of infection, biology and ecology of their intermediate cyprinid hosts...
  37. ncbi High excretion of etheno adducts in liver fluke-infected patients: protection by praziquantel against DNA damage
    Somkid Dechakhamphu
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Cancer Epidemiol Biomarkers Prev 17:1658-64. 2008
    ..Urinary epsilondA and epsilondC levels should be explored (a) as noninvasive risk markers for developing opisthorchiasis-related CCA and (b) as promising biomarkers to assess the efficacy of preventive and therapeutic interventions...
  38. pmc Genetic variation at three enzyme loci within a Thailand population of Opisthorchis viverrini
    Weerachai Saijuntha
    Walai Rukhavej Botanical Research Institute, Mahasarakham University, Mahasarakham 44150, Thailand
    Parasitol Res 103:1283-7. 2008
    ..This heterozygote deficiency suggests non-random mating and/or potentially high self fertilization...
  39. pmc Human illnesses caused by Opisthorchis felineus flukes, Italy
    Orlando Armignacco
    Belcolle Hospital, Viterbo, Italy
    Emerg Infect Dis 14:1902-5. 2008
    ..Of the 22 infected persons, 10 (45.4%) were asymptomatic. When present, symptoms (fever, nausea, abdominal pain, and myalgias) were mild. Eosinophilia occurred in all infected persons...
  40. ncbi Biological variation within Opisthorchis viverrini sensu lato in Thailand and Lao PDR
    Nonglak Laoprom
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen 40002, Thailand
    J Parasitol 95:1307-13. 2009
    ..These results support the genetic/molecular data indicating a subdivision of O. viverrini populations on the basis of watershed and that propose the existence of cryptic species in Thailand and the Lao PDR...
  41. ncbi The systematics and population genetics of Opisthorchis viverrini sensu lato: implications in parasite epidemiology and bile duct cancer
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:32-7. 2012
    ..viverrini may contribute to recorded local and regional differences in epidemiology and host morbidity in opisthorchiasis and cholangiocarcinoma (CCA). In this review, we address recent findings that O...
  42. ncbi Viable metacercariae of Opisthorchis viverrini in northeastern Thai cyprinid fish dishes--as part of a rational program for control of O. viverrini-associated cholangiocarcinoma
    Jiraporn Prasongwatana
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Parasitol Res 112:1323-7. 2013
    Among the various types of chronic helminthic infections, only schistosomiasis hematobium, opisthorchiasis, and clonorchiasis in a long-standing inflammation are found to be causative agents of cancer...
  43. ncbi Specific serum IgG, but not IgA, antibody against purified Opisthorchis viverrini antigen associated with hepatobiliary disease and cholangiocarcinoma
    Porntip Pinlaor
    Centre for Research and Development in Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:212-6. 2012
    b>Opisthorchiasis caused by Opisthorchis viverrini infection induces hepatobiliary disease (HBD)-associated cholangiocarcinoma (CCA) via a chronic inflammatory immune response...
  44. ncbi Affinity purified oval antigen for diagnosis of Opisthorchiasis viverrini
    T Wongsaroj
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Bangkok, Thailand
    Asian Pac J Allergy Immunol 19:245-58. 2001
    ..e. opisthorchiasis in Thailand. The antibodies were used in an affinity column to purify the O...
  45. pmc Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini
    Banchob Sripa
    Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand
    PLoS Negl Trop Dis 6:e1654. 2012
    ..viverrini, but to the development of the advanced and often lethal pathologies resulting from chronic O. viverrini infection...
  46. ncbi Opisthorchis felineus, an emerging infection in Italy and its implication for the European Union
    Edoardo Pozio
    European Union Reference Laboratory for Parasites, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Acta Trop 126:54-62. 2013
    ..from freshwater snails to fish and then to fish-eating mammals, including humans, in which it causes opisthorchiasis. In the 20th century, the majority of infections in humans have been reported in Eastern Europe (e.g...
  47. ncbi Acute renal failure in obstructive jaundice in cholangiocarcinoma
    P Mairiang
    Department of Medicine, Khon Kaen Thailand, University
    Arch Intern Med 150:2357-60. 1990
    ..Clinical data highlight the higher serum bilirubin levels and the frequent occurrence of hyponatremia, hypokalemia, and hypotension in renal failure. Their possible roles in contributing to the development of renal failure are discussed...
  48. pmc The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002 Thailand
    Trends Parasitol 28:395-407. 2012
    ..Here we review the pathogenesis of opisthorchiasis and the association between O...
  49. ncbi Monophyly of Opisthorchis viverrini populations in the lower Mekong Basin, using mitochondrial DNA nad1 gene as the marker
    Urusa Thaenkham
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Parasitol Int 59:242-7. 2010
    ..viverrini species complex should be rejected. The bio-geographical diversity of O. viverrini populations should be explored further, using other appropriate markers and a wider range of samples from geographically different areas...
  50. ncbi Opisthorchis felineus and Metorchis bilis are the main agents of liver fluke infection of humans in Russia
    Viatcheslav A Mordvinov
    Institute of Cytology and Genetics Siberian Branch of RAS, Novosibirsk, Russia
    Parasitol Int 61:25-31. 2012
    ..trematode belonging to the family Opisthorchiidae, is a well known causative agent of the infection called opisthorchiasis. Metorchis bilis, also a member of the family Opisthorchiidae, causes metorchiasis, a disease very close to ..
  51. ncbi Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis
    Watcharin Loilome
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:136-9. 2012
    ..These results suggest that OSBP2 and OSBPL-7 might serve as molecular markers for the identification of CCA metastasis in the bloodstream...
  52. ncbi A large outbreak of Opisthorchis felineus in Italy suggests that opisthorchiasis develops as a febrile eosinophilic syndrome with cholestasis rather than a hepatitis-like syndrome
    A Traverso
    Infectious Diseases Unit, U Parini Hospital, Aosta, Italy
    Eur J Clin Microbiol Infect Dis 31:1089-93. 2012
    We describe the greatest Italian human acute opisthorchiasis outbreak acquired from eating raw tenches. Out of 52 people with suspected opisthorchiasis, 45 resulted in being infected...
  53. ncbi Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial
    Phonepasong Soukhathammavong
    National Institute of Public Health, Ministry of Health, Vientiane, Laos
    Lancet Infect Dis 11:110-8. 2011
    ..We aimed to assess the efficacy and safety of these drugs compared with that of praziquantel in patients with O viverrini infection...
  54. ncbi Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis
    Jae Hoon Lim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Abdom Imaging 33:157-65. 2008
    ..In the biliary phase, the flukes are demonstrated in the intra- and extrahepatic bile ducts and the gallbladder as small intraluminal flat objects, sometimes moving spontaneously. Bile ducts are dilated...
  55. ncbi Experimental investigation of opisthorchiasis-associated cholangiocarcinoma induction in the Syrian hamster - pointers for control of the human disease
    Suchart Chaimuangraj
    Urology Department of Surgery, Ramathibodi Hospital, Rama VI, Bangkok 10400, Thailand
    Asian Pac J Cancer Prev 4:87-93. 2003
    ....
  56. pmc Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos
    Banchob Sripa
    Tropical Disease Research Laboratory, Department of Pathology, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 120:S158-68. 2011
    ..b>Opisthorchiasis has been studied extensively in Thailand, where about 8 million people are infected with the liver fluke...
  57. pmc Seasonal variation of Opisthorchis viverrini infection in cyprinoid fish in north-east Thailand: implications for parasite control and food safety
    P Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Thailand
    Bull World Health Organ 75:125-31. 1997
    ..Samples of fish were collected in 1991-92 at monthly intervals from two areas-Khon Kaen Province, where the opisthorchiasis transmission rate was high, and Mahasarakham Province, where the rate was low...
  58. ncbi Pathobiology of opisthorchiasis: an update
    Banchob Sripa
    Division of Experimental Pathology, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:209-20. 2003
    ..This review summarizes the pathology of opisthorchiasis from literature mainly published between 1970 and the present time and, particularly, emphasizes on current ..
  59. pmc Evidence of a species complex within the food-borne trematode Opisthorchis viverrini and possible co-evolution with their first intermediate hosts
    Weerachai Saijuntha
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Int J Parasitol 37:695-703. 2007
    ..Our findings have major implications for the implementation of effective control and surveillance programs targeted to these medically important food-borne parasites...
  60. ncbi Ultrasound screening for Opisthorchis viverrini-associated cholangiocarcinomas: experience in an endemic area
    Eimorn Mairiang
    Department of Radiology, Cancer Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Asian Pac J Cancer Prev 7:431-3. 2006
    ..Most people (77%) had normal U/S findings while only 0.5% had suspected CHCA; thus, U/S should be used primarily for those with the highest risk, presenting symptoms and/or being OV positive...
  61. ncbi Hepatobiliary changes, antibody response, and alteration of liver enzymes in hamsters re-infected with Opisthorchis viverrini
    Somchai Pinlaor
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Exp Parasitol 108:32-9. 2004
    ..This study emphasizes that there is an important relationship between the gradual decreases of inflammation with a concomitant increase in fibrosis after re-infection...
  62. ncbi The diagnosis of human opisthorchiasis
    Natsuda Jamornthanyawat
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:86-91. 2002
    b>Opisthorchiasis viverrini is a liver fluke infection causing a serious public health problem in Thailand, Lao PDR, Cambodia, and South Vietnam because it acts as a strong promoter of cholangiocarcinoma...
  63. ncbi Clinical manifestation of opisthorchiasis and treatment
    Eimorn Mairiang
    Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:221-7. 2003
    This paper presents an overview of recent progress in the clinical study of opisthorchiasis and treatment...
  64. pmc Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6
    Banchob Sripa
    Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand
    Hepatology 50:1273-81. 2009
    ..O. viverrini-infected individuals with advanced periductal fibrosis showed other hepatobiliary abnormalities, including reduced gallbladder contractility and the presence of gallbladder sludge...
  65. pmc Opisthorchis viverrini: an underestimated parasite in world health
    Ross H Andrews
    University of South Australia, GPO Box 2471, Adelaide South Australia, Australia 5001, Australia
    Trends Parasitol 24:497-501. 2008
    ..Future research should determine the relationship between the genetic variability of O. viverrini and patterns of opisthorchiasis-related disease.
  66. ncbi Proteomic identification of peroxiredoxin 6 for host defence against Opisthorchis viverrini infection
    J Khoontawad
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasite Immunol 32:314-23. 2010
    Opisthorchis viverrini infection causes opisthorchiasis and is a risk factor for cholangiocarcinoma via chronic inflammation. To investigate the mechanism of O...
  67. ncbi Involvement of MMP-9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1-dependent DNA damage in a hamster model
    Suksanti Prakobwong
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Int J Cancer 127:2576-87. 2010
    ..The results suggest that MMP-9 expression is associated with the accumulation of peribiliary fibrosis in conjunction to the induction of iNOS and Rac1 that may potentiate DNA damage and cholangiocarcinogenesis...
  68. ncbi Relationships between the synthesis of N-nitrosodimethylamine and immune responses to chronic infection with the carcinogenic parasite, Opisthorchis viverrini, in men
    S Satarug
    National Research Centre for Environmental Toxicology, Coopers Plains, Queensland, Australia
    Carcinogenesis 19:485-91. 1998
    ..viverrini-infected humans...
  69. ncbi Biliary liver flukes (Opisthorchiasis and Clonorchiasis) in immigrants in the United States: often subtle and diagnosed years after arrival
    William M Stauffer
    Pediatric and Medicine Faculty, Regions Hospital Healthpartners, Center for International Health and International Travel Clinic, 640 Jackson Street, St Paul, MN 55101, USA
    J Travel Med 11:157-9. 2004
    ..It was noted that several cases presenting at our center had been in the US for prolonged periods. This prompted us to retrospectively review cases of liver fluke infection diagnosed at our facility...
  70. ncbi Clonorchis sinensis and Opisthorchis viverrini: development of a mitochondrial-based multiplex PCR for their identification and discrimination
    Thanh Hoa Le
    Institute of Biotechnology, Viet Nam
    Exp Parasitol 112:109-14. 2006
    ..here proved to be a species-specific, sensitive and fast tool for accurate diagnosis of clonorchiasis and/or opisthorchiasis, permitting the detection of their metacercariae in infected fishes or adult/eggs from patients in endemic ..
  71. pmc Asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and its potential for serodiagnosis
    Thewarach Laha
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Int J Infect Dis 12:e49-59. 2008
    ..To isolate and characterize an asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and evaluate its expression profile, biochemical activity, and potential as an immunodiagnostic antigen...
  72. ncbi Opisthorchis viverrini and opisthorchiasis: a historical review and future perspective
    E S Upatham
    Department of Medical Science, Faculty of Science, Burapha University, Bangsaen, Chonburi 20131, Thailand
    Acta Trop 88:171-6. 2003
    b>Opisthorchiasis is caused by the liver fluke, Opisthorchis viverrini. The fluke afflicts approximately seven million inhabitants in northeastern and northern Thailand...
  73. ncbi Prevalence of Opisthorchis viverrini infection among villagers harboring Opisthorchis-like eggs
    K L Sukontason
    Department of Parasitology, Faculty of Medicine, Chiang Mai University, Thailand
    Southeast Asian J Trop Med Public Health 32:23-6. 2001
    ..viverrini: H. taichui eggs in mixed infection cases was 2.29 (min = 1, max = 17.5). It is suggested that chemotherapy with praziquentel treatment should be given to patients who are positive for O. viverrini-like eggs...
  74. ncbi Localisation of parasite antigens and inflammatory responses in experimental opisthorchiasis
    B Sripa
    Division of Experimental Pathology, Department of Pathology, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand
    Int J Parasitol 30:735-40. 2000
    ..The results strongly support the role of fluke-associated antigens and local parasite-specific immune responses in the pathogenesis of opisthorchiasis.
  75. ncbi A focus of opisthorchiidosis in Germany
    S Hering-Hagenbeck
    Institute for Biology, Humboldt University, Berlin, Germany
    Appl Parasitol 37:260-5. 1996
    ..R. rutilus and A. alburnus showed a prevalence of Opisthorchis of more than 70%. Two out of 166 Bithynia leachi were positive for trematode developmental stages. Due to their young age the rediae could not be specified...
  76. ncbi Enzyme markers to identify and characterize Opisthorchis viverrini in Thailand and Lao PDR
    Weerachai Saijuntha
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Southeast Asian J Trop Med Public Health 37:43-7. 2006
    ....
  77. ncbi Opisthorchis viverrini and opisthorchiasis: the 21st century review
    B Sripa
    Acta Trop 88:169-70. 2003
  78. ncbi Evaluation of PCR based coprodiagnosis of human opisthorchiasis
    C R Stensvold
    Danish Bilharziasis Laboratory DBL, Institute for Health Research and Development, Jaergersborg Allé 1D, DK 2920 Charlottenlund, Denmark
    Acta Trop 97:26-30. 2006
    ....
  79. ncbi Enhancement of DHPN induced hepatocellular, cholangiocellular and pancreatic carcinogenesis by Opisthorchis viverrini infestation in Syrian golden hamsters
    W Thamavit
    Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Carcinogenesis 9:1095-8. 1988
    ....
  80. ncbi [Opisthorchiasis simulating a malignancy]
    B Berger
    Allgemeines Krankenhaus St Georg, Institut fur Pathologie, Hamburg
    Z Gastroenterol 39:173-5. 2001
    ..The Opisthorchiasis is endemic in large areas of Asia and Russia. Humans acquire the infection by eating raw fresh-water fish...
  81. ncbi Relationship between intensity of Opisthorchis viverrini infection and hepatobiliary disease detected by ultrasonography
    E Mairiang
    Nongrua District Hospital, Khon Kaen Province, Thailand
    J Gastroenterol Hepatol 7:17-21. 1992
    ..Two suspected cases of cholangiocarcinoma were identified from the heavy group. The results highlight the importance of intensity of infection on the frequency and severity of fluke-associated hepatobiliary disease...
  82. ncbi Gall bladder and extrahepatic bile duct changes in Opisthorchis viverrini-infected hamsters
    Banchob Sripa
    Department of Pathology, Division of Experimental Pathology, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand
    Acta Trop 83:29-36. 2002
    ..is associated with several hepatobiliary diseases, but few reports have described extrahepatic lesions in opisthorchiasis. We therefore sequentially investigated histological changes of the gall bladder and extrahepatic bile duct ..
  83. ncbi Liver and intestinal flukes
    L X Liu
    Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Gastroenterol Clin North Am 25:627-36. 1996
    ..Zoonotic trematode infections include the sheep liver fluke F. hepatica and the intestinal flukes Fasciolopsis, Echinostoma, Heterophyes, and Metagonimus...
  84. ncbi Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment
    Somchai Pinlaor
    Department of Parasitology, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Am J Trop Med Hyg 78:564-73. 2008
    ..viverrini antigen release. Data in this study can be used as a basis to understand potential side effects of praziquantel treatment in humans...
  85. ncbi Association of parasitic infections and cancers
    S Khurana
    Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Indian J Med Microbiol 23:74-9. 2005
    ..The evidence for the association of several other parasites and cancers has also been postulated...
  86. ncbi Serodiagnosis of human opisthorchiasis using cocktail and electroeluted Bithynia snail antigens
    Jitra Waikagul
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Parasitol Int 51:237-47. 2002
    ..The performance of these two antigens in the antibody detection of human opisthorchiasis was evaluated by indirect ELISA. Serum samples from people whose stool was either: (i)...
  87. ncbi [Clinical effectiveness of dehelmintization in patients with psoriasis accompanied by chronic opisthorchosis]
    S A Khardikova
    Klin Med (Mosk) 83:48-51. 2005
    ..Thus, effective dehelmintization allowed improvement of alimentary tract functional condition and the clinical course of psoriasis...
  88. ncbi TaqMan real-time PCR assay for specific detection of Opisthorchis viverrini DNA in Thai patients with hepatocellular carcinoma and cholangiocarcinoma
    Nithikoon Suksumek
    Division of Molecular Laboratory, Vachira Hospital, Bangkok 10400, Thailand
    Exp Parasitol 119:217-24. 2008
    ..193; 90%CI). This RT-PCR will be a useful tool for investigating the relationship between cancer type and presence of the parasite and also for conducting epidemiological surveys...
  89. pmc Improvement of PCR for detection of Opisthorchis viverrini DNA in human stool samples
    Kunyarat Duenngai
    Department of Parasitology, Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Clin Microbiol 46:366-8. 2008
    ..01). PCR-positive tests identified several cases judged parasite negative by the parasitological method (28.6%), indicating the new test's advantage in the diagnosis of individuals with light infections...
  90. pmc Specific and common antigens of Clonorchis sinensis and Opisthorchis viverrini(Opisthorchidae, Trematoda)
    Min Ho Choi
    Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul 110 799, Korea
    Korean J Parasitol 41:155-63. 2003
    ..The frequency and intensity of the immunoblot reactions were positively correlated with the intensity of the liver fluke infection...
  91. ncbi Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini
    C Thuwajit
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitology 129:455-64. 2004
    ..viverrini; this finding may clarify how O. viverrini ES product(s) affect human bile duct epithelium during cholangiocarcinogenesis...
  92. ncbi Cholangiocarcinoma: recent progress. Part 1: epidemiology and etiology
    Kunio Okuda
    Department of Medicine, Chiba University School of Medicine, Chiba, Japan
    J Gastroenterol Hepatol 17:1049-55. 2002
    ....
  93. ncbi Opisthorchiasis-associated biliary stones: light and scanning electron microscopic study
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    World J Gastroenterol 10:3318-21. 2004
    Biliary stones are frequently encountered in areas endemic for opisthorchiasis in Thailand. The present study was to describe the prevalence and pathogenesis of these stones.
  94. ncbi Equivocal evidence of complete carcinogenicity after repeated infection of Syrian hamsters with Opisthorchis viverrini
    W Thamavit
    Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Toxicol Pathol 24:493-7. 1996
    ....
  95. ncbi [A case of severe eosinophilia in the acute phase of Opisthorchis viverrini infection]
    Hiroshi Nishiura
    Department of Infectious Diseases, Tokyo Metropolitan Ebara General Hospital
    Kansenshogaku Zasshi 77:677-81. 2003
    ..It was considered eosinophilia in this case was induced by acute phase of severe ophisthorchiasis...
  96. ncbi Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase
    Somchai Pinlaor
    Department of Environmental and Molecular Medicine and Department of Anatomy, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Carcinogenesis 25:1535-42. 2004
    ....
  97. ncbi Histological analysis of gallbladder diseases in relation to opisthorchiasis in endemic areas of Thailand
    Banchob Sripa
    Division of Experimental Pathology, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:239-46. 2003
    ..The close relationship between parasite-specific IgG and severe fibrosis suggests that specific immune response to the parasite play an important role in the pathogenesis of the fibrotic change...
  98. ncbi [Experimental grounds of a new concept of Opisthorchis felineus infection formation in a definitive host]
    F P Kovalenko
    Parazitologiia 39:257-62. 2005
    ..felineus infection in the bilious duct of definitive hosts is performed by means of hematogenic migration of metacercariae through the portal veins system from the mucous layer of the alimentary tract of the host...
  99. ncbi Opisthorchis viverrini: identification of a glycine-tyrosine rich eggshell protein and its potential as a diagnostic tool for human opisthorchiasis
    Jiraporn Ruangsittichai
    Department of Biology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Int J Parasitol 36:1329-39. 2006
    ..Comparison of rOvESP with the parasite's excretion/secretion products as diagnostic tools for human opisthorchiasis shows a higher sensitivity (0.82-0.48) and specificity (0.97-0...
  100. ncbi A pilot screening of prevalence of atopic states and opisthorchosis and their relationship in people of Tomsk Oblast
    L M Ogorodova
    Siberian State Medical University, Tomsk, Russia
    Parasitol Res 101:1165-8. 2007
    ..The data obtained confirm the negative association of rural lifestyle and atopic diseases prevalence and indicate that O. felineus invasion might be a modifying factor of this relationship in Tomsk Oblast...

Research Grants4

  1. Space Renovation for New Research Center for the Neglected Diseases of Poverty
    John Williams; Fiscal Year: 2010
    ..health, with faculty members conducting fundamental NIH-sponsored research on hookworm, schistosomiasis, opisthorchiasis, and toxoplasmosis, as well as epidemiological and policy work...
  2. Pathogenesis, Carcinogenesis and Ecology of Opisthorchiasis in Thailand
    Banchob Sripa; Fiscal Year: 2013
    This TMRC application deals with the neglected tropical disease, opisthorchiasis, caused by infection with the fish-borne trematode parasite, Opisthorchis viverrini...
  3. MODULATION OF LIVER FLUKE-ASSOCIATED NEOPLASIA
    Nobuyuki Ito; Fiscal Year: 1990
    ..The influence of repeated infection and chemotherapy will also be investigated. Since the observed opisthorchiasis-dependent enhancement of neoplasia in both man and the hamster appears directly related to the hyperplastic ..
  4. Risk Factors for HIV-1 infection Among Young Thai Men
    Ram Rangsin; Fiscal Year: 2009
    ..We propose a case control study of HIV-1 infected young men and their 1:4 controls matched on year of birth, district of residence, and type of conscription. ..