central nervous system parasitic infections

Summary

Summary: Infections of the brain, spinal cord, and meninges caused by parasites, primarily PROTOZOA and HELMINTHS.

Top Publications

  1. ncbi Parasitic central nervous system infections: echinococcus and schistosoma
    Kiarash Shahlaie
    Department of Neurological Surgery, University of California, Davis Medical Center, Davis, CA, USA
    Rev Neurol Dis 2:176-85. 2005
  2. ncbi Parasitic worms of the central nervous system: an Australian perspective
    A J Hughes
    University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Intern Med J 32:541-53. 2002
  3. ncbi Secondary infection of intracranial hydatid cyst with Clostridium ramosum
    Omer Faruk Turkoglu
    Department of Neurosurgery, Ankara Numune Research and Education Hospital, Turkey
    Childs Nerv Syst 21:1004-7. 2005
  4. ncbi Parasitic central nervous system infections in immunocompromised hosts: clarification of malaria diagnosis
    William M Stauffer
    Clin Infect Dis 43:114-5; author reply 115-6. 2006
  5. ncbi Echinococcosis presenting as an otogenic brain abscess: an unusual lesion of the middle ear cleft and temporal lobe
    Erasmo Gonzalo D V Llanes
    Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital University Hospital, University of Berne, 3010 Berne, Switzerland
    Auris Nasus Larynx 35:115-20. 2008
  6. ncbi Imaging of rickettsial, spirochetal, and parasitic infections
    Ayca Akgoz
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neuroimaging Clin N Am 22:633-57. 2012
  7. ncbi Dental management of the tropical disease human African trypanosomiasis: an unusual case of pseudobulbar palsy
    L Frost
    Solent Healthcare Dental Service, Dental Department, Bitterne Health Centre, Commercial Street, Southampton, Hampshire, SO18 6BT
    Br Dent J 210:13-6. 2011
  8. ncbi Rickettsiae, protozoa, and opisthokonta/metazoa
    Erich Schmutzhard
    Department of Neurology, Medical University Hospital Innsbruck, Innsbruck, Austria Electronic address
    Handb Clin Neurol 121:1403-43. 2014
  9. ncbi Parasitoses of the human central nervous system
    J Finsterer
    Krankenanstalt Rudolfstiftung, Vienna, Austria
    J Helminthol 87:257-70. 2013
  10. ncbi Presumptive central nervous system cuterebriasis and concurrent protein-losing nephropathy in a dog
    Vincent J Thawley
    Section of Critical Care, Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Emerg Crit Care (San Antonio) 23:335-9. 2013

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Publications88

  1. ncbi Parasitic central nervous system infections: echinococcus and schistosoma
    Kiarash Shahlaie
    Department of Neurological Surgery, University of California, Davis Medical Center, Davis, CA, USA
    Rev Neurol Dis 2:176-85. 2005
    ..Ongoing advancements in neuroimaging and diagnostic studies, as well as efforts to better understand the parasite genome and host-parasite relationships, will likely continue to improve patient management...
  2. ncbi Parasitic worms of the central nervous system: an Australian perspective
    A J Hughes
    University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Intern Med J 32:541-53. 2002
    ..Specific risk factors that predispose to these infections are also discussed and particular attention is drawn to the situation in Australia...
  3. ncbi Secondary infection of intracranial hydatid cyst with Clostridium ramosum
    Omer Faruk Turkoglu
    Department of Neurosurgery, Ankara Numune Research and Education Hospital, Turkey
    Childs Nerv Syst 21:1004-7. 2005
    ..Brain involvement in hydatid disease occurs in 1-2% of all Echinococcus granulosus infections. Secondary infection of intracranial hydatid cysts is extremely rare...
  4. ncbi Parasitic central nervous system infections in immunocompromised hosts: clarification of malaria diagnosis
    William M Stauffer
    Clin Infect Dis 43:114-5; author reply 115-6. 2006
  5. ncbi Echinococcosis presenting as an otogenic brain abscess: an unusual lesion of the middle ear cleft and temporal lobe
    Erasmo Gonzalo D V Llanes
    Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital University Hospital, University of Berne, 3010 Berne, Switzerland
    Auris Nasus Larynx 35:115-20. 2008
    ..Evacuation of the brain abscess was performed with a combined otolaryngologic and neurosurgical procedures (canal wall-down mastoidectomy and temporal craniotomy). The pathology turned out to be infestation with Echinococcus granulosus...
  6. ncbi Imaging of rickettsial, spirochetal, and parasitic infections
    Ayca Akgoz
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neuroimaging Clin N Am 22:633-57. 2012
    ..Being familiar with clinical presentation and imaging findings of these infections is crucial for early diagnosis and treatment especially in patients who live in or have a travel history to endemic regions or are immunocompromised...
  7. ncbi Dental management of the tropical disease human African trypanosomiasis: an unusual case of pseudobulbar palsy
    L Frost
    Solent Healthcare Dental Service, Dental Department, Bitterne Health Centre, Commercial Street, Southampton, Hampshire, SO18 6BT
    Br Dent J 210:13-6. 2011
    ..Changes in disease demographics require the dental profession to increase its awareness of migration medicine and the appropriate dental management of such diseases...
  8. ncbi Rickettsiae, protozoa, and opisthokonta/metazoa
    Erich Schmutzhard
    Department of Neurology, Medical University Hospital Innsbruck, Innsbruck, Austria Electronic address
    Handb Clin Neurol 121:1403-43. 2014
    ....
  9. ncbi Parasitoses of the human central nervous system
    J Finsterer
    Krankenanstalt Rudolfstiftung, Vienna, Austria
    J Helminthol 87:257-70. 2013
    ..g. Angiostrongylus costaricensis) or whether they remain undetected or asymptomatic, like 25% of neurocysticerciasis cases. ..
  10. ncbi Presumptive central nervous system cuterebriasis and concurrent protein-losing nephropathy in a dog
    Vincent J Thawley
    Section of Critical Care, Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Emerg Crit Care (San Antonio) 23:335-9. 2013
    ..To describe the clinical course and successful management of a dog suspected to have central nervous system (CNS) Cuterebra larval migration and concurrent protein-losing nephropathy (PLN)...
  11. ncbi Parasitic disorders
    Charles R Newton
    KEMRI Wellcome Collaborative Programme, Kilifi, Kenya Electronic address
    Handb Clin Neurol 112:1139-52. 2013
    ..Most parasitic conditions can be treated, but in some diseases it is unclear whether the treatment influences outcome...
  12. ncbi Mechanisms of CNS invasion and damage by parasites
    Krister Kristensson
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden Electronic address
    Handb Clin Neurol 114:11-22. 2013
    ..Finally, examples are given which illustrate different mechanisms by which parasites can cause dysfunction or damage in the CNS related to toxic effects of parasite-derived molecules or to immune responses to the infection. ..
  13. ncbi Pathology of CNS parasitic infections
    José Eymard Homem Pittella
    Pathology Service, Hospital das Clinicas, Medical Faculty of Ribeirão Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil Electronic address
    Handb Clin Neurol 114:65-88. 2013
    ..Some infections may be present as an expanding mass lesion. The parasites can be identified by conventional histology, immunohistochemistry, in situ hybridization, and PCR...
  14. ncbi Baylisascaris larva migrans
    Kevin R Kazacos
    Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA
    Handb Clin Neurol 114:251-62. 2013
    ..procyonis. Baylisascaris procyonis has also been found in kinkajous in the USA and South America and may also occur in related procyonids (coatis, olingos, etc.). ..
  15. pmc Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria
    Judith Miklossy
    International Alzheimer Research Center, Prevention Alzheimer Foundation, Martigny Combe, Switzerland
    J Neuroinflammation 8:90. 2011
    ..Spirochetal infection occurs years or decades before the manifestation of dementia. As adequate antibiotic and anti-inflammatory therapies are available, as in syphilis, one might prevent and eradicate dementia...
  16. pmc Babesia lengau associated with cerebral and haemolytic babesiosis in two domestic cats
    Anna Mari Bosman
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    Parasit Vectors 6:128. 2013
    ..Babesia lengau, recently described from asymptomatic cheetahs, has now possibly been incriminated as the causative agent in two severe clinical cases in domestic cats...
  17. pmc Cerebral schistosomiasis due to Schistosoma haematobium confirmed by PCR analysis of brain specimen
    Kentaro Imai
    Department of Infectious Diseases and Applied Immunology, Research Hospital of the Institute of Medical Science, The University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    J Clin Microbiol 49:3703-6. 2011
    ..Although serum antibody tests showed a cross-reaction with other helminths and no ova were excreted in urine or feces, the existence of Schistosoma haematobium in the brain was confirmed by PCR analysis...
  18. ncbi Spine infections
    John L Go
    Division of Neuroradiology, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Neuroimaging Clin N Am 22:755-72. 2012
    ..This article reviews the underlying pathophysiologic basis of infection, clinical manifestations, and imaging modalities used to diagnose infections of the spine and spinal cord...
  19. pmc Neurologic complications of HIV-1 infection and its treatment in the era of antiretroviral therapy
    Sarah M Kranick
    National Institutes of Health, Building 10, 6 5700, Bethesda, MD 20892, USA
    Continuum (Minneap Minn) 18:1319-37. 2012
    ..Additionally, as successful virologic control has extended the life span of patients with HIV infection, neurologists are called upon to manage long-term complications, such as neurocognitive disorders and peripheral neuropathy...
  20. ncbi Pathology of tropical diseases
    Nuzhat Husain
    Department of Pathology, Dr Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow, Uttar Pradesh, India
    Neuroimaging Clin N Am 21:757-75, vii. 2011
    ..Nutritional disorders present with generalized and nonspecific imaging manifestations. The pathology of commonly encountered vitamin deficiencies is also discussed...
  21. ncbi Parasitic diseases of the central nervous system
    Ahmed Abdel Khalek Abdel Razek
    Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Neuroimaging Clin N Am 21:815-41, viii. 2011
    ..Combining imaging findings with geographic prevalence, clinical history, and serologic tests is required for diagnosis of parasitic diseases of the central nervous system...
  22. ncbi Epidemiology of central nervous system infection
    James Riddell
    Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109 5378, USA
    Neuroimaging Clin N Am 22:543-56. 2012
    ..This article reviews and discusses the changing epidemiology of pathogens most often observed in meningitis, brain abscess, epidural abscess, postoperative infections, and human immunodeficiency virus infection...
  23. pmc A retrospective study of spinal cord lesions in goats submitted to 3 veterinary diagnostic laboratories
    Andrew L Allen
    Department of Veterinary Pathology and Prairie Diagnostic Services, Inc, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada
    Can Vet J 53:639-42. 2012
    ....
  24. ncbi [Parasitic and fungal neuroinfections at the Infectious Diseases Clinic in Fann Teaching Hospital in Dakar]
    M Soumare
    Clinique des Maladies Infectieuses CHU de Fann, BP 5035, Dakar, Senegal
    Mali Med 24:31-4. 2009
    ..This retrospective study was carried out to describe the epidemiological, clinical and aetiological profile of parasitic and fungal neuroinfections at the Infectious Diseases Clinic in Fann Teaching Hospital in Dakar...
  25. pmc Update on eosinophilic meningoencephalitis and its clinical relevance
    Carlos Graeff-Teixeira
    Laboratório de Biologia Parasitária, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, 91619 900 Porto Alegre, Brazil
    Clin Microbiol Rev 22:322-48, Table of Contents. 2009
    ..Thus, distinctive identification of eosinophils in fluids is a necessary component in the etiologic diagnosis of CNS infections...
  26. ncbi Parasitic brain infection, endocannabinoids, and schizophrenia
    Robert Melamede
    Biology Department, University of Colorado at Colorado, Springs, Colorado Springs, CO 80918, USA
    Med Hypotheses 72:220-2. 2009
    ....
  27. ncbi Multiple infected cerebral hydatid cysts
    R Gana
    Department of Neurosurgery, Ibn Sina Hospital, Hopital Avicenne, Souissi, Rabat, Morocco
    J Clin Neurosci 15:591-3. 2008
    ..The aim of surgery is to remove the cyst unruptured and this should be followed by antihelminthic and antibiotic treatment in order to avoid recurrences...
  28. doi Primary central nervous system vasculitis in a child mimicking parasitosis
    C Kamm
    J Neurol 255:130-2. 2008
  29. ncbi Visceral larva migrans presenting as multiple intracranial and intraspinal abscesses
    Alefia Moiyadi
    Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, India
    Neuropathology 27:371-4. 2007
    ....
  30. ncbi Intraprostatic hydatid cyst: an unusual presentation
    Yassine Nouira
    Department of Urology, La Rabta Hospital, Tunis, Tunisia
    ScientificWorldJournal 6:2315-8. 2006
    ..Postoperative course was uneventful and follow-up did not show evidence of recurrence. This is the first case of hydatid cyst of the prostate to present as an intraprostatic stone pouch...
  31. ncbi Neurohydatidosis
    J M E Kovoor
    Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka 560029, India
    Australas Radiol 51:406-11. 2007
    ..Early and non-invasive evaluation of hydatid infestation of brain and spine is of paramount importance, especially in endemic areas. We present a spectrum of imaging findings in neurohydatidosis with a brief review of literature...
  32. ncbi Toxocariasis of the CNS simulating acute disseminated encephalomyelitis
    C Marx
    Department of Neurology and Neurosurgery, Federal University of Sao Paulo, Sao Paulo, Brazil
    Neurology 69:806-7. 2007
  33. ncbi [Descriptive epidemiology of extrapulmonary hydatid cysts: a report of 265 Tunisian cases]
    Salma Bellil
    Service d Anatomie Pathologique, Hopital La Rabta, Tunis
    Tunis Med 87:123-6. 2009
    ..Hydatidosis is a parasitic endemic disease in Tunisia. The liver and lung are the most common sites of involvement; however, it can develop anywhere in the body...
  34. ncbi [Neuroradiologic imaging results suggestive of parasitic cysts in central nervous system in course of neoplastic disorders--cases report]
    Agnieszka Muszyńska
    Uniwersytet Medyczny w Białymstoku, Klinika Chorób Zakaźnych i Neuroinfekcji
    Pol Merkur Lekarski 26:645-8. 2009
    ....
  35. ncbi [Clinical analysis of 78 cases of parasitic encephalopathy]
    Shu Mei Wang
    Department of Infectious Disease, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 27:245-8. 2009
    ..To investigate the epidemiology, clinical characteristics, therapeutic approaches and outcomes of parasitic encephalopathy...
  36. ncbi Protozoa traversal of the blood-brain barrier to invade the central nervous system
    Hany M Elsheikha
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK
    FEMS Microbiol Rev 34:532-53. 2010
    ..Advances in understanding the molecular pathways will offer opportunities for the rational development of novel therapeutic interventions...
  37. ncbi [Cerebrovascular disease in the tropics]
    O H Del Brutto
    Departamento de Ciencias Neurologicas, Hospital Clinica Kennedy, Guayaquil, Ecuador
    Rev Neurol 33:750-62. 2001
    ..To review the clinical manifestations, diagnosis, and therapy of diseases causing cerebrovascular disease (CVD) in the tropics...
  38. ncbi Atypical radiological findings in cerebral hydatid disease
    Mohammed Benzagmout
    Department of Neurosurgery, University Hospital Hassan II, Fez, Morocco
    Neurosciences (Riyadh) 16:263-6. 2011
    ..An MRI was helpful in the diagnosis of the 2 cases. Both patients underwent successful surgery with a good outcome. The hydatid nature of the cyst was confirmed by histology in both cases...
  39. ncbi Trichobilharzia regenti: host immune response in the pathogenesis of neuroinfection in mice
    Lucie Lichtenbergová
    Department of Parasitology, Faculty of Science, Charles University in Prague, Vinicna 7, 128 44 Prague 2, Czech Republic
    Exp Parasitol 128:328-35. 2011
    ..Immunoreactivity of the parasite intestinal content for specific antigens of oligodendrocytes/myelin and neurofilaments showed for the first time that schistosomula ingest the nervous tissue components during their migration...
  40. ncbi Subarachnoid basal neurocysticercosis: a focus on the most severe form of the disease
    Agnes Fleury
    Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico UNAM, Mexico City, Mexico
    Expert Rev Anti Infect Ther 9:123-33. 2011
    ..We provide a critical review of the central epidemiological, clinical, diagnostic and therapeutic features of this particular form of the disease, which is still associated with unacceptably high rates of morbidity and mortality...
  41. ncbi Spine infection/inflammation
    Jeffrey DeSanto
    Neuroradiology Department, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013, USA
    Radiol Clin North Am 49:105-27. 2011
    ..Subsequently, several infectious pathogenic agents are discussed individually as they affect the spinal column and its contents...
  42. ncbi Parasitic diseases of the central nervous system
    Geeta Chacko
    Division of Neuropathology, Department of Neurological Sciences, Christian Medical College, Vellore, India
    Semin Diagn Pathol 27:167-85. 2010
    ..In this review of the pathology of parasitic infections that affect the CNS, each parasite is discussed in the sequence of epidemiology, life cycle, pathogenesis, and pathology...
  43. ncbi Non-vertebrate models to study parasite invasion of the central nervous system
    Ruqaiyyah Siddiqui
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK, LE12 5RD, United Kingdom
    Trends Parasitol 27:5-10. 2011
    ..Improving our knowledge of these core processes might elevate the efficiency of therapy of diseases caused by them...
  44. ncbi Helminth infections of the central nervous system occurring in Southeast Asia and the Far East
    Shan Lv
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People s Republic of China
    Adv Parasitol 72:351-408. 2010
    ..Finally, risk factors, and research needs for enhanced patient management and population-based control measures are discussed...
  45. ncbi Isolation and identification of Acanthamoeba species related to amoebic encephalitis and nonpathogenic free-living amoeba species from the rice field
    S Y Liang
    Institute of Oral Biology, School of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Appl Microbiol 109:1422-9. 2010
    ..Isolation and characterization of the clinically relevant amphizoic amoebas in vegetated farmlands, which may present a risk to farmers' health...
  46. ncbi Diagnosis and stereotactic aspiration treatment of cerebral sparganosis: summary of 11 cases
    Lei Deng
    Department of Neurosurgery, No 94 Hospital of People s Liberation Army, Nanchang, Jiangxi Province, People s Republic of China
    J Neurosurg 114:1421-5. 2011
    ....
  47. ncbi Emergent neuroimaging of intracranial infection/inflammation
    Mark E Mullins
    Department of Radiology, Emory University School of Medicine, 1364 Clifton Road NE, Room D125A, Atlanta, GA 30322, USA
    Radiol Clin North Am 49:47-62. 2011
    ..This article reviews some of the salient factors in understanding intracranial infection/ inflammation, including pathophysiology and neuroimaging protocols/findings, and provides some examples and a few "pearls and pitfalls."..
  48. ncbi MRI of cerebral alveolar echinococcosis
    M Tunaci
    Department of Radiology, Istanbul Medical Faculty, PK 112 Acibadem, Kadikoy, Istanbul, Turkey
    Neuroradiology 41:844-6. 1999
    ..We report a case with multiple intracranial masses which show cauliflower-like contrast enhancement pattern on MRI. The lesions originated from hepatic involvement with invasion of the inferior vena cava...
  49. ncbi Parasites and the brain: neuroinvasion, immunopathogenesis and neuronal dysfunctions
    K Kristensson
    Department of Neuroscience, Retzius vag 8, Karolinska Institutet, 171 77 Stockholm, Sweden
    Curr Top Microbiol Immunol 265:227-57. 2002
  50. ncbi Submandibular and intracranial hydatid cyst in an adolescent
    Onder Guney
    Department of Neurosurgery, Selcuk University Faculty of Medicine, Konya, Turkey
    Laryngoscope 112:1857-60. 2002
    ..Review of the pertinent literature did not reveal any hydatid disease located simultaneously in both the intracranial and submandibular glands. This is the first case with hydatid disease occurring in both locations at the same time...
  51. ncbi Infectious myelopathies
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington 40536, USA
    Semin Neurol 22:133-42. 2002
    ..This review addresses the infectious myelopathies by microorganism...
  52. ncbi [Investigation of inpatient cases of food-borne parasitic encephalopathy]
    Chun yu Yin
    Department of Infectious Diseases, Affiliated Huashan Hospital of Fudan University, Shanghai 200040
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 20:177-9. 2002
    ..To investigate the clinical features of the patients with encephalopathy caused by food-borne parasites...
  53. ncbi Chronic cerebral paragonimiasis combined with aneurysmal subarachnoid hemorrhage
    Juk Dong Choo
    Department of Neurosurgery, Sun General Hospital, Daejeon, Republic of Korea
    Am J Trop Med Hyg 69:466-9. 2003
    ..Overall, this case was diagnosed as chronic cerebral paragonimiasis, in which she may have been infected through the contamination of utensils during the preparation of the second intermediate hosts, combined with a cerebral hemorrhage...
  54. ncbi Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi-infected suckling rats
    Grace C Silva
    Department of Morphology, Federal University of Minas Gerais, Av Antonio Carlos, 6627, 31270 901 Belo Horizonte, Minas Gerais, Brazil
    J Neuroimmunol 149:50-8. 2004
    ..Occludin immunoreactivity remained as in uninfected animals. Our results indicate a role for blood-born macrophages in both parasite invasion and brain reaction. Microglia activation cannot be discarded...
  55. ncbi Chest pain after travel to the tropics
    Luigia Elzi
    Division of Infectious Diseases University Hospital Basel CH 4002 Basel, Switzerland
    Lancet 363:1198. 2004
  56. ncbi Infection of organotypic slice cultures from rat central nervous tissue with Neospora caninum: an alternative approach to study host-parasite interactions
    Nathalie Vonlaufen
    Institute of Parasitology, University of Berne, Langgass strasse 122, 3012, Berne, Switzerland
    Int J Parasitol 32:533-42. 2002
    ..caninum within the context of neuronal tissue, which at the same time can be modulated and influenced under controlled conditions, and will be useful in the future to gain more information on the cerebral phase of neosporosis...
  57. ncbi [Calcified cerebral hydatid cyst. Report of a case]
    M Choukri
    Service de Neurochirurgie, CHU Ibn Rochd, Casablanca, Maroc
    J Neuroradiol 28:261-3. 2001
    ..The evolution has been favourable with improvement of the left hemiparesis. The calcified hydatid cyst of brain is still exceptional, its symptomatology is the same as the safe CHC, but it poses some diagnostic and therapeutic problems...
  58. ncbi Cerebral hydatid cysts in children
    S Kocaman
    Division of Pediatric Neurosurgery, Ege University Faculty of Medicine, Bornova, Izmir, Turkey
    J Neurosci Nurs 31:270-7. 1999
    ..Hydatid disease can also be seen in Western countries because of travel and migration. Cerebral hydatid cyst should be kept in mind for the differential diagnosis of cystic lesions...
  59. ncbi Parasitic lesion of the insula suggesting cerebral sparganosis: case report
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Neuroradiology 42:206-8. 2000
    ..We describe the MRI appearances and pathologic features. Intracranial mass lesions secondary to sparganosis must be considered in patients with a history of travel to endemic areas, especially Asia...
  60. ncbi Imaging of rickettsial, spirochetal, and parasitic infections
    C M Kornbluth
    Department of Radiology, St Luke s Roosevelt Hospital Center, New York, NY, USA
    Neuroimaging Clin N Am 10:375-90. 2000
    ..Many of the infections, however, are endemic to certain parts of the world and are seen with increasing frequency in immunocompromised individuals...
  61. ncbi Use of the capture-recapture method for determining the prevalence of neurological parasitic diseases
    John H Lange
    Neuroepidemiology 23:99; author reply 99-100. 2004
  62. ncbi Central nervous system hydatidosis in Turkey: a cooperative study and literature survey analysis of 458 cases
    N Altinors
    Neurosurgery Department, Baskent University, Ankara, Turkey
    J Neurosurg 93:1-8. 2000
    ..The aim of this study was to analyze central nervous system (CNS) involvement in this disease, the related problems the disease causes, and its diagnostic and therapeutic aspects...
  63. ncbi Infection of organotypic slice cultures from rat central nervous tissue with Trypanosoma brucei brucei
    L Stoppini
    Department of Pharmacology, Centre Medical Universitaire, Geneva, Switzerland
    Int J Med Microbiol 290:105-13. 2000
    ..Secondly, it provides, to the best of our knowledge, the first in vitro demonstration of intracellular forms of African trypanosomes...
  64. ncbi Clinics in diagnostic imaging (58). Chronic cerebral paragonimiasis
    G J Kaw
    Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore
    Singapore Med J 42:89-91. 2001
    ..CT scan confirmed the presence of large calcified nodules in the corresponding regions. These imaging findings were typical of chronic cerebral paragonimiasis. The clinical, CT and MR features of cerebral paragonimiasis are reviewed...
  65. ncbi Neural sarcocystosis in a straw-necked ibis (Carphibis spinicollis) associated with a Sarcocystis neurona-like organism and description of muscular sarcocysts of an unidentified Sarcocystis species
    J R Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Beltsville, Maryland 20705 2350, USA
    J Parasitol 87:1317-22. 2001
    ..The villar protrusions on the sarcocyst wall were up to 4.5 microm long, constricted at the base, and expanded laterally. Schizonts and sarcocysts distinct from those of S. falcatula...
  66. ncbi Review of epidemiological studies searching for a relationship between onchocerciasis and epilepsy
    M Druet-Cabanac
    Institute of Neuroepidemiology and Tropical Neurology EA 3174, Limoges, France
    Neuroepidemiology 23:144-9. 2004
    ..However, the results are nearly significant. Further research is needed in this neglected subject, in particular for the better understanding of the neurological pathogenicity in onchocerciasis...
  67. ncbi Report of diffusion-weighted MRI in two cases with different cerebral hydatid disease
    O Kitis
    Ege University, Faculty of Medicine, Department of Radiology, Bornova, Izmir, Turkey
    Acta Radiol 45:85-7. 2004
    ..To present MRI findings in two cases of cerebral hydatid disease with an emphasis on diffusion-weighted imaging (DWI) findings of Echinococcus granulosus (EG) versus Echinococcus alveolaris (EA)...
  68. ncbi [Parasitic diseases in the central nervous system]
    Yukifumi Nawa
    University of Miyazaki
    Rinsho Shinkeigaku 45:891-3. 2005
    ..They accidentally migrate into CNS to cause deleterious conditions. Clinicians should always remind about the possibility of parasitic diseases when they make differential diagnosis for CNS diseases...
  69. pmc Parasitic central nervous system infections in immunocompromised hosts: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis
    Melanie Walker
    Department of Neurology, University of Washington School of Medicine, Seattle, Washington, USA
    Clin Infect Dis 42:115-25. 2006
    ..This review will discuss the presentation, diagnosis, and treatment of the following additional parasitic CNS infections: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis...
  70. ncbi Cerebral alveolar echinoccosis mimicking primary brain tumor
    S Senturk
    Department of Radiology, Hacettepe University, Sihhiye, Ankara, Turkey
    AJNR Am J Neuroradiol 27:420-2. 2006
    ..Perfusion-weighted MR imaging revealed low relative cerebral blood volume within the calcified lesion and peripheral hyperemia. Single-voxel proton MR spectroscopy with an echo time of 135 milliseconds was normal...
  71. ncbi Microbial translocation of the blood-brain barrier
    Kwang Sik Kim
    Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Park 256, Baltimore, MD 21287, USA
    Int J Parasitol 36:607-14. 2006
    ..This review summarises our current understanding of the pathogenic mechanisms involved in translocation of the BBB by meningitis-causing bacteria, fungi and parasites...
  72. ncbi Cestode parasitic infestation: intracranial and spinal hydatid disease--a clinicopathological study of 29 cases from South India
    M Rumana
    Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, India
    Clin Neuropathol 25:98-104. 2006
    ..None of the cases had anaphylactic reaction, with no significant post-operative morbidity and no mortality. One intracranial and 2 spinal lesions caused by fertile cysts recurred to undergo repeated surgery...
  73. ncbi Onchocerciasis-related epilepsy? Prospects at a time of uncertainty
    Benoit Marin
    Institut de Neuroépidémiologie et de Neurologie Tropicale EA 3174, Faculte de Medecine, 2 rue de Docteur Marcland, 87025 Limoges Cedex, France
    Trends Parasitol 22:17-20. 2006
    ..volvulus strains; (iii) immunological mechanisms involving cross-reactive immunization or cytokine production during infection; and (iv) the triggering role of insomnia due to itching...
  74. ncbi Seroprevalence of Helicobacter pylori among children in Sana'a, Yemen
    Hassan A Al-Shamahy
    University of Sana a, Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Sana a, Yemen
    Ann Saudi Med 25:299-303. 2005
    ..pylori immunoglobulin G (IgG) in Yemeni children under 10 years of age, the potential risk factors for contracting H. pylori infection and co-infection of H. pylori with intestinal parasites...
  75. ncbi Primary intracranial hydatid cyst in the interpeduncular cistern
    E Beskonakli
    Department of Neurosurgery, Ankara Numune Research and Education Hospital, Ankara, Turkey
    Acta Neurochir (Wien) 147:781-3; discussion 783. 2005
    ..In this report, a case of 33-year-old male with primary intracranial hydatid cyst in the interpeduncular cistern is reported. This is the first such case in the literature...
  76. ncbi Ophthalmomyiasis (interna posterior) of the posterior segment and central nervous system myiasis: Cuterebra spp. in a cat
    Milton Wyman
    MedVet Columbus, 300 E Wilson Bridge Road, Worthington, OH 43085, USA
    Vet Ophthalmol 8:77-80. 2005
    ..The larva was demonstrated by histopathology with coagulation necrosis and hemorrhage of the optic nerve, retina and choroid, and anterior uveitis. No significant cerebrum and anterior brain stem lesions were found...
  77. ncbi Central nervous system infections
    Zoran Rumboldt
    Department of Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
    Semin Roentgenol 42:62-91. 2007
  78. ncbi Multiple organ involvement hydatid cysts in a 2-year-old boy
    Omer Iyigun
    Department of Neurosurgery, School of Medicine, Ondokuz Mayis University, Samsun, Turkey
    J Trop Pediatr 50:374-6. 2004
    ..We suggest that a differential diagnosis of hydatid cyst should be considered when a brain mass is found in a patient, even 2 years old, from an endemic area of echinococcosis...
  79. ncbi Balamuthia mandrillaris, an opportunistic agent of granulomatous amebic encephalitis, infects the brain via the olfactory nerve pathway
    Albrecht F Kiderlen
    Department of Infectious Diseases, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Parasitol Res 94:49-52. 2004
    ..A similar invasion pathway has been described for N. fowleri. The data suggest that the olfactory nerve pathway is a likely route for natural infection of the brain by B. mandrillaris amebae...
  80. ncbi Granulomatous diseases of the central nervous system
    Antonio Jose da Rocha
    Department of Neuroradiology, Santa Casa de Misericordia de Sao Paulo, Brazil
    Top Magn Reson Imaging 16:155-87. 2005
    ..Taking these parameters into account we will discuss the several patterns of image found in parasitic, bacterial, and fungal granulomatous infections...
  81. ncbi Infections of the central nervous system in transplant recipients
    N Singh
    VA Medical Center and University of Pittsburgh, Thomas E Starzl Transplantation Institute, Pittsburgh, Pennsylvania 15240, USA
    Transpl Infect Dis 2:101-11. 2000
    ....
  82. ncbi [Neurotrichinosis]
    K Knezevic
    Klinicki centar, Novi Sad
    Med Pregl 54:483-5. 2001
    ..Central nervous system complications can occur during the course of this disease. This paper presents a case of neurotrichinellosis, assayed by using indirect immunofluorescence test...
  83. ncbi [Imaging of a historical case of vertebral hydatidosis]
    M Mahi
    Service d Imagerie Medicale, hôpital militaire d instruction Mohamed V, Rabat, Maroc
    J Neuroradiol 28:244-8. 2001
    ..Radiological, computed tomography and magnetic resonance imaging findings in a case of spinal hydatidosis are reported...
  84. ncbi Chronic meningitis
    Raimund Helbok
    Dept of Neurology, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    J Neurol 256:168-75. 2009
    ..However, most patients with idiopathic chronic meningitis have a relatively good outcome...
  85. ncbi Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis
    Yvonne Qvarnstrom
    Division of Parasitic Disease, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    J Infect Dis 199:1139-42. 2009
    ..The results illustrate the potential for other free-living amoebae, which are not normally associated with human disease, to cause occasional infections...
  86. ncbi [Cerebral hydatic cyst and psychiatric disorders. Two cases]
    F Asri
    Service Universitaire Psychiatrique, CHU Mohamed VI, Faculte de Medecine, Universite Cadi Ayyad, Marrakech, Maroc
    Encephale 33:216-9. 2007
    ..We are conscious of the methodological difficulties that present these 2 cases but there are unfortunately due to the financial difficulties of our patients...
  87. ncbi [Inflammatory and infectious manifestations of the nervous system]
    G P Pizzolato
    Unité de neuropathologie, Hopital Universitaire de Geneve
    Rev Med Suisse Romande 119:799-804. 1999
    ..We will review recent progress in our knowledge about transmissible spongiformes encephalopathies and AIDS-associated lesions, and briefly discuss cerebral vasculitis, granulomatous diseases and the most frequent infections by parasites...
  88. ncbi Isolated cerebral hydatid cysts: a comparative study of two different types of presentations
    T Patankar
    Dept of Radiology, KEM Hospital, Mumbai, India
    J Assoc Physicians India 47:805-8. 1999
    ..To demonstrate the existence of two imaging patterns of cerebral hydatidosis and discuss its clinical importance...

Research Grants7

  1. GP 120 MEDIATED ACTIVATION OF BRAIN ENDOTHELIAL CELLS
    Kwang Kim; Fiscal Year: 2002
    ..e., roles of G proteins and signaling pathways, platelet-activating factor (PAF). The information derived from this proposal should enhance our understanding of the role of HBMEC in HIV encephalopathy. ..
  2. E. COLI BINDING TO BRAIN ENDOTHELIAL CELLS
    Kwang Kim; Fiscal Year: 2003
    ....
  3. Ethanol, Tat and the Blood-brain barrier
    Kwang Kim; Fiscal Year: 2004
    ..e., nitric oxide and signaling pathways. The information derived from this proposal should enhance our understanding of the role of ethanol in HIV-1 neuropthogenesis. ..
  4. Cryptococcus traversal of Brain Endothelial cells
    Kwang Kim; Fiscal Year: 2007
    ..neoformans traversal of HBMEC monolayers and will be the basis of future investigations to characterize microbial-host interactions that are relevant to the pathogenesis of cryptococcal meningitis/meningoencephalitis. ..
  5. Genome-wide screening of E. coli for bacteremia
    Kwang Kim; Fiscal Year: 2007
    ..coli bacteremia should help in development of preventive measures such as vaccines against E. coli bacteremia. [unreadable] [unreadable] [unreadable]..
  6. Treatment for Canine Diabetic Cataracts
    Milton Wyman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  7. E. coli invasion of brain endothelial cells
    Kwang Kim; Fiscal Year: 2008
    ..3.To determine the role of K1 capsule in E. coli trafficking in HBMEC. Further understanding and characterization of E. coli K1-HBMEC interactions should allow us to develop novel strategies to prevent this serious infection. ..