paranasal sinus neoplasms

Summary

Summary: Neoplasms or tumors of the paranasal sinuses. Malignant neoplasms are rare, comprising 3% of all head and neck neoplasms. The majority arise in the maxillary sinus with malignancies of the ethmoid sinus constituting virtually all the remaining tumors.

Top Publications

  1. ncbi Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review
    P Dulguerov
    Division of Head and Neck Surgery, Department of Surgery, University of California Los Angeles, Los Angeles, California, USA
    Cancer 92:3012-29. 2001
  2. ncbi Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection
    V J Lund
    University College London, Ear Institute, London, United Kingdom
    Rhinology 50:203-10. 2012
  3. ncbi Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review
    N Clifton
    Department of Otolaryngology, Head and Neck Surgery, Queen s Medical Centre Campus, Nottingham, UK
    J Laryngol Otol 125:479-85. 2011
  4. ncbi Primary sinonasal malignant melanoma: a nationwide study of the Swedish population, 1960-2000
    M Jangard
    Department of Oto Rhino Laryngology, Karolinska University Hospital, Stockholm, Sweden
    Rhinology 51:22-30. 2013
  5. ncbi Paranasal sinus malignancies: an 18-year single institution experience
    Larry L Myers
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390 9035, USA
    Laryngoscope 112:1964-9. 2002
  6. ncbi Carcinoma of the nasal cavity and paranasal sinuses
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610 0385, USA
    Laryngoscope 119:899-906. 2009
  7. ncbi Treatment planning comparison of conventional, 3D conformal, and intensity-modulated photon (IMRT) and proton therapy for paranasal sinus carcinoma
    Ulrike Mock
    Department of Radiotherapy and Radiobiology, University Hospital Vienna, Vienna, Austria
    Int J Radiat Oncol Biol Phys 58:147-54. 2004
  8. ncbi Endoscopic resection of sinonasal inverted papilloma: a meta-analysis
    Jose M Busquets
    Department of Otolaryngology Head and Neck Surgery, Oregon Health and Science University, Portland, OR, USA
    Otolaryngol Head Neck Surg 134:476-82. 2006
  9. pmc K-ras mutations in sinonasal cancers in relation to wood dust exposure
    Jette Bornholdt
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    BMC Cancer 8:53. 2008
  10. ncbi Intensity-modulated radiotherapy for sinonasal tumors: Ghent University Hospital update
    Indira Madani
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 73:424-32. 2009

Detail Information

Publications223 found, 100 shown here

  1. ncbi Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review
    P Dulguerov
    Division of Head and Neck Surgery, Department of Surgery, University of California Los Angeles, Los Angeles, California, USA
    Cancer 92:3012-29. 2001
    ..The authors reviewed treatment results in patients with nasal and paranasal sinus carcinoma from a large retrospective cohort and conducted a systematic literature review...
  2. ncbi Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection
    V J Lund
    University College London, Ear Institute, London, United Kingdom
    Rhinology 50:203-10. 2012
    ..Melanomas account for 4% of sinonasal malignancies. We present the largest single institution series reported thus far and analyze the outcome with reference to lymph node involvement, radiotherapy and endoscopic resection...
  3. ncbi Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review
    N Clifton
    Department of Otolaryngology, Head and Neck Surgery, Queen s Medical Centre Campus, Nottingham, UK
    J Laryngol Otol 125:479-85. 2011
    ..To report our experience of the management of patients with primary sinonasal malignant melanoma, and to review the relevant medical literature...
  4. ncbi Primary sinonasal malignant melanoma: a nationwide study of the Swedish population, 1960-2000
    M Jangard
    Department of Oto Rhino Laryngology, Karolinska University Hospital, Stockholm, Sweden
    Rhinology 51:22-30. 2013
    ..To establish population-based trends for sinonasal mucosal melanoma (SNMM) in Sweden...
  5. ncbi Paranasal sinus malignancies: an 18-year single institution experience
    Larry L Myers
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390 9035, USA
    Laryngoscope 112:1964-9. 2002
    ..To characterize a single institution experience with management of paranasal sinus malignancies during an 18-year time period, report long-term survival rates, and identify prognostic factors...
  6. ncbi Carcinoma of the nasal cavity and paranasal sinuses
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610 0385, USA
    Laryngoscope 119:899-906. 2009
    ..To determine the outcomes after radiotherapy (RT) alone or combined with surgery at the University of Florida for patients with carcinomas of the nasal cavity and paranasal sinuses...
  7. ncbi Treatment planning comparison of conventional, 3D conformal, and intensity-modulated photon (IMRT) and proton therapy for paranasal sinus carcinoma
    Ulrike Mock
    Department of Radiotherapy and Radiobiology, University Hospital Vienna, Vienna, Austria
    Int J Radiat Oncol Biol Phys 58:147-54. 2004
    ..To determine the potential improvements in patients with paranasal sinus carcinoma by comparing proton and intensity-modulated radiotherapy (IMRT) with conventional and conformal photon treatment planning techniques...
  8. ncbi Endoscopic resection of sinonasal inverted papilloma: a meta-analysis
    Jose M Busquets
    Department of Otolaryngology Head and Neck Surgery, Oregon Health and Science University, Portland, OR, USA
    Otolaryngol Head Neck Surg 134:476-82. 2006
    ..This study aims to systematically review and integrate the available literature to objectively compare success rates of endoscopic versus nonendoscopic tumor resection techniques...
  9. pmc K-ras mutations in sinonasal cancers in relation to wood dust exposure
    Jette Bornholdt
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    BMC Cancer 8:53. 2008
    ..In previous small studies of this cancer, ras mutations were suggested to be related to wood dust exposure, but these studies were too limited to detect statistically significant associations...
  10. ncbi Intensity-modulated radiotherapy for sinonasal tumors: Ghent University Hospital update
    Indira Madani
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 73:424-32. 2009
    ..To report the long-term outcome of intensity-modulated radiotherapy (IMRT) for sinonasal tumors...
  11. ncbi Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 101:2567-73. 2004
    ..The authors reviewed their institutional experience to determine whether sinonasal neuroendocrine tumors of different histologies have distinct clinical characteristics that warrant individualized treatment approaches...
  12. ncbi Decreasing incidence of malignant tumors of the paranasal sinuses in Sweden. An analysis of 141 consecutive cases at Karolinska Hospital from 1960 to 1980
    Tomas Norlander
    Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
    Ann Otol Rhinol Laryngol 112:236-41. 2003
    ..7 to 0.3 for female patients between 1960 and 1980. We conclude that the incidence of malignant paranasal sinus tumors has decreased, and that squamous cell tumors now seem to be generally less differentiated than they were 50 years ago...
  13. ncbi Endoscopic management of inverted papillomas of the nose and paranasal sinuses
    Paramita Baruah
    Department of Otorhinolaryngology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Ear Nose Throat J 82:317-20. 2003
    ..We believe that endoscopic surgery is ideally suited for the treatment of appropriately selected patients who have limited disease and who are likely to adhere conscientiously to a regular follow-up program...
  14. ncbi Demographics and treatment trends in sinonasal mucosal melanoma
    Thomas J Gal
    Division of Otolaryngology Head and Neck Surgery, University of Kentucky, Lexington, Kentucky 40536, USA
    Laryngoscope 121:2026-33. 2011
    ..To evaluate the population characteristics of mucosal melanoma of the nasal cavity and paranasal sinuses and determine the impact of the new staging classification...
  15. pmc Expression of mismatch repair proteins, beta catenin, and E cadherin in intestinal-type sinonasal adenocarcinoma
    B Perez-Ordonez
    Department of Pathology, University Health Network, Princess Margaret Hospital, 610 University Avenue, Room 4 304, Toronto, Ontario M4N 3M5, Canada
    J Clin Pathol 57:1080-3. 2004
    ..Despite their histological resemblance to colorectal adenocarcinomas, there is little information about the molecular events involved in the pathogenesis of intestinal-type sinonasal adenocarcinomas (ITACs)...
  16. ncbi Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance
    Sue S Yom
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Mod Pathol 18:315-9. 2005
    ....
  17. ncbi Prediction of TP53 status for primary cisplatin, fluorouracil, and leucovorin chemotherapy in ethmoid sinus intestinal-type adenocarcinoma
    L Licitra
    Medical Oncology Department, Head and Neck Unit, Istituto Nazionale Tumori, Via Venezian 1, 20133 Milan, Italy
    J Clin Oncol 22:4901-6. 2004
    ..To assess the role of TP53 status in predicting pathologic complete remission after primary chemotherapy in patients with ethmoidal intestinal-type adenocarcinoma (ITAC)...
  18. ncbi Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm
    Wish Banhiran
    Department of Otolaryngology, University of Miami School of Medicine, University of Miami Hospital and Clinics, Miami, Florida 33136, USA
    Curr Opin Otolaryngol Head Neck Surg 13:50-4. 2005
    ..The following represents a review of the recent literature on the latest trends regarding endoscopic resection of nasal and paranasal sinus neoplasms.
  19. ncbi p53 and BCL-2 over-expression inversely correlates with histological differentiation in occupational ethmoidal intestinal-type sinonasal adenocarcinoma
    M Re
    Department of Otorhinolaryngology, Marche Polytechnic University, Ancona, Italy
    Int J Immunopathol Pharmacol 24:603-9. 2011
    ..The relationship between up-regulation of p53 and Bcl-2 and poorly differentiated ethmoidal adenocarcinoma suggests a role of these genes, in combination with additional genetic events, in the pathogenesis of ITAC...
  20. ncbi Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses
    Milo Frattini
    Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, 20133 Milan, Italy
    Head Neck 28:909-15. 2006
    ..Our aim was to verify whether the morphologic resemblances mirror genetic profile similarities...
  21. ncbi Intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses. A clinicopathologic study of 6 cases
    J I Lopez
    Service of Pathology, Hospital Civil de Bilbao, Spain
    Tumori 76:250-4. 1990
    ..Data pooled from the literature reveal that 53% of patients have experienced local recurrences following therapy, and 60% have died of their disease. Of these deaths, 80% occurred within 5 years of diagnosis...
  22. ncbi Role of endoscopic approach in the management of inverted papilloma
    Filippo Carta
    Department of Ear, Nose and Throat, Hopital Lariboisiere, AP HP, Paris, Universite Paris Diderot, Paris, France
    Curr Opin Otolaryngol Head Neck Surg 19:21-4. 2011
    ....
  23. ncbi Endoscopic management of inverted papillomas: long-term results--the St. Paul's Sinus Centre experience
    Carl M Philpott
    St Paul s Sinus Centre, St Paul s Hospital, Vancouver, BC, Canada
    Rhinology 48:358-63. 2010
    ..To demonstrate that computer-assisted endoscopic management of inverted papillomas yields excellent long-term results in terms of preventing recurrence and minimizing significant morbidity and mortality...
  24. ncbi Sinonasal mucosal melanomas
    B Lietin
    Service d ORL et de chirurgie de la Face et du Cou, Universite d Auvergne, CHU, BP 69, 58, rue Montalembert, 63003 Clermont Ferrand Cedex 01, France
    Eur Ann Otorhinolaryngol Head Neck Dis 127:70-6. 2010
    ..Metastases are frequent. The main objective of this study was to analyze all of our cases of sinonasal mucosal melanomas and determine any prognostic factors...
  25. pmc Is routine histopathological examination of FESS material useful?
    Cindy van den Boer
    Department of Otolaryngology Head Neck Surgery, Sint Lucas Andreas Hospital, P O Box 9243, 1006AE, Amsterdam, The Netherlands
    Eur Arch Otorhinolaryngol 267:381-4. 2010
    ..In patients in whom there is a high degree of suspicion for (pre)malignancy, histopathological examination of functional endoscopic sinsus surgery material remains indicated...
  26. ncbi Sinonasal malignancies with neuroendocrine differentiation: case series and review of literature
    Santosh Menon
    Department of Pathology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
    Indian J Pathol Microbiol 53:28-34. 2010
    ..They can be distinguished based on immunohistochemical characteristics. Pathological sub categorization is imperative for management and prognostication of these aggressive tumors...
  27. ncbi Primary malignant tumors of the sphenoidal sinus
    F DeMonte
    Department of Neurosurgery, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Neurosurgery 46:1084-91; discussion 1091-2. 2000
    ..Primary involvement of the sphenoidal sinus has been reported to occur in only 1 to 2% of all paranasal sinus tumors. Tumors at this site commonly present with cranial neuropathies and require multidisciplinary treatment...
  28. ncbi [Paralateral-nasal malignant schwannoma with rhabdomyoblastic differentiation (Triton tumor). Report of a case]
    M Re
    Istituto di Scienze Odontostomatologiche, Cattedra di Clinica Otorinolaringoiatrica, Universita di Ancona
    Acta Otorhinolaryngol Ital 22:245-7. 2002
    ..We report a case of a 64-year-old man who presented a right paralatero-nasal Triton tumor. Following exeresis, a cycle of high-dose radiotherapy was prescribed; the 10-year follow-up revealed no sign of recurrence or distant metastases...
  29. ncbi Osteoma of the ethmoidal sinus: a rare case of recurrence
    Lambros Zouloumis
    Department of Oral and Maxillofacial Surgery, School of Dentistry, Aristotle University of Thessaloniki, Greece
    Br J Oral Maxillofac Surg 43:520-2. 2005
    ..The patient presented with proptosis, epiphora, and headaches. We approached the lesion and removed it through a lateral nasal incision. Two years later the patient was free of symptoms...
  30. ncbi Intraparenchymal tension pneumatocele complicating frontal sinus osteoma: case report
    David Johnson
    Department of Neurosurgery, Gold Coast Hospital, Southport, Queensland, Australia
    Neurosurgery 50:878-9; discussion 880. 2002
    ..The scanty body of literature on this subject is briefly summarized, and the importance of this condition as a result of its life-threatening but readily treatable intracranial mass effect is outlined...
  31. ncbi Proton beam therapy for unresectable malignancies of the nasal cavity and paranasal sinuses
    Sadamoto Zenda
    Division of Radiation Oncology, National Cancer Center Hospital East, Chiba, Japan
    Int J Radiat Oncol Biol Phys 81:1473-8. 2011
    ..We retrospectively analyzed the clinical profile of PBT for unresectable malignancies of the nasal cavity and paranasal sinuses...
  32. ncbi Proton radiation therapy for primary sphenoid sinus malignancies: treatment outcome and prognostic factors
    Minh Tam Truong
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Head Neck 31:1297-308. 2009
    ..The purpose of this study was to determine treatment outcome and prognostic factors in patients with locally advanced primary sphenoid sinus malignancy treated with proton radiation therapy...
  33. pmc Tobacco use and sinonasal cancer: a case-control study
    R B Hayes
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892
    Br J Cancer 56:843-6. 1987
    ..The study findings indicate that tobacco use, and in particular recent tobacco use, is associated with the development of squamous cell sinonasal cancer...
  34. ncbi Conformal radiotherapy for paranasal sinus and nasal cavity tumors: three-dimensional treatment planning and preliminary results in 40 patients
    P Pommier
    Department of Radiation Oncology, Centre Leon Berard, Lyon, France
    Int J Radiat Oncol Biol Phys 48:485-93. 2000
    ..To assess the possibility to deliver a high and homogeneous irradiation with respect to maximal tolerated dose to the visual pathways for paranasal sinus and nasal cavity tumors...
  35. ncbi Neuroendocrine tumors of the sinonasal tract. Results of a prospective study incorporating chemotherapy, surgery, and combined proton-photon radiotherapy
    Markus M Fitzek
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 94:2623-34. 2002
    ..The authors report the results of a prospective study of patients with malignant neuroendocrine tumors of the sinonasal tract who received multimodality treatment incorporating high-dose proton-photon radiotherapy...
  36. ncbi Unresectable carcinoma of the paranasal sinuses: outcomes and toxicities
    Bradford S Hoppe
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Int J Radiat Oncol Biol Phys 72:763-9. 2008
    ..To evaluate long-term outcomes and toxicity in patients with unresectable paranasal sinus carcinoma treated with radiotherapy, with or without chemotherapy...
  37. ncbi Carcinoma of paranasal sinuses: long-term outcomes with radiotherapy
    Angel I Blanco
    Department of Radiation Oncology, Washington University, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 59:51-8. 2004
    ..To assess the clinical features, prognostic factors, results, and complications of treatment of carcinomas of the paranasal sinus...
  38. ncbi An evolution in the management of sinonasal inverting papilloma
    J K Han
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226
    Laryngoscope 111:1395-400. 2001
    ..Difference in recurrence rates was not observed between the endoscopic and the external approach groups. Recurrence rates are lower for primary resection versus secondary resection, regardless of surgical approach...
  39. ncbi Nasal and paranasal sinus carcinoma: how can we continue to make progress?
    Pavel Dulguerov
    Geneva University Hospital, Department of Otolaryngology Head and Neck Surgery, Geneva, Switzerland
    Curr Opin Otolaryngol Head Neck Surg 14:67-72. 2006
    ..New developments in the nasal and paranasal sinus cancers are reviewed...
  40. ncbi Endoscopic management of benign sinonasal tumors: a decade of experience
    Scott D London
    Department of Otolaryngology, Head and Neck Surgery, University of Virginia Health Sciences Center, Charlottesville 22908 0713, USA
    Am J Rhinol 16:221-7. 2002
    ..A variety of benign tumors present in the nasal and paranasal sinuses...
  41. ncbi Malignant tumors of the nasal cavity and paranasal sinuses: long-term outcome and morbidity with emphasis on hypothalamic-pituitary deficiency
    An Snyers
    Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Radiat Oncol Biol Phys 73:1343-51. 2009
    ..To evaluate the long-term outcome after surgery and radiotherapy for patients with sinonasal cancer and assess late toxicity, with special emphasis on hypothalamic-pituitary dysfunction...
  42. pmc A case-control study on occupational risk factors for sino-nasal cancer
    A d'Errico
    Local Health Unit ASL TO3, Epidemiology Department Piedmont Region, Via Sabaudia 164, Grugliasco TO 10095, Italy
    Occup Environ Med 66:448-55. 2009
    ..The aim of this study was to investigate the risk of sino-nasal epithelial cancer (SNEC) by histological type with prior exposure to suspected occupational risk factors and, in particular, those in metalworking...
  43. ncbi Magnetic resonance imaging findings of inverted papilloma: differential diagnosis with malignant sinonasal tumors
    Roberto Maroldi
    Department of Radiology, University of Brescia, Italy
    Am J Rhinol 18:305-10. 2004
    ..The present retrospective study was performed in the attempt to identify distinguishing features of IP on MRI...
  44. ncbi Malignant neoplasms of the sinonasal tract: report of 71 patients and literature review and analysis
    Bijan Khademi
    Department of Otolaryngology, and Head and Neck Surgery, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz 71936 13311, Iran
    Oral Maxillofac Surg 13:191-9. 2009
    ..The present study aimed to report the characteristics, prognostic factors, and treatment outcomes of 71 cases of malignant neoplasms of the sinonasal tract and literature review and analysis of major report series...
  45. ncbi The roles and limitations of computed tomography in the preoperative assessment of sinonasal inverted papillomas
    C L Sham
    Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Am J Rhinol 22:144-50. 2008
    ..This study investigates the roles and limitations of preoperative plain computed tomography (CT) scan in the preoperative assessment of SNIP...
  46. ncbi Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like features
    Jonathan B McHugh
    Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
    Arch Pathol Lab Med 133:1587-93. 2009
    ..Osteomas may have osteoblastoma-like areas and distinguishing it from true osteoblastoma can be challenging. Some believe osteomas with osteoblastoma-like features behave more aggressively...
  47. ncbi Endoscopic surgery for recurrent inverted papilloma
    Ta Jen Lee
    Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Laryngoscope 114:106-12. 2004
    ..The study determined the effectiveness of endoscopic surgery for recurrent inverted papilloma and described when endoscopic medial maxillectomy was indicated...
  48. ncbi Proton beam radiation therapy for skull base adenoid cystic carcinoma
    Pascal Pommier
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Otolaryngol Head Neck Surg 132:1242-9. 2006
    ..To determine the treatment outcome and prognostic factors in patients with adenoid cystic carcinoma of the skull base treated with proton beam radiation therapy...
  49. ncbi Cigarette smoking increases risk of recurrence for sinonasal inverted papilloma
    Il Joon Moon
    Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul, Korea
    Am J Rhinol Allergy 24:325-9. 2010
    ..This study was performed to evaluate clinical and environmental factors including smoking that can predict neoplasm recurrence after surgery in patients with IP...
  50. ncbi Visual outcome of accelerated fractionated radiation for advanced sinonasal malignancies employing photons/protons
    Damien C Weber
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Radiother Oncol 81:243-9. 2006
    ..To investigate the visual outcomes of patients with advanced sinonasal malignancies treated with proton/photon accelerated fractionated radiation (AFR)...
  51. ncbi Long-term results of endonasal sinus surgery in sinonasal papillomas
    Marcel Kraft
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Lausanne, Switzerland
    Laryngoscope 113:1541-7. 2003
    ..To assess the value of endonasal sinus surgery in the management of sinonasal papillomas...
  52. ncbi Sino-nasal cancer in Denmark 1982-1991--a nationwide survey
    C Grau
    Department of Oncology, Aarhus University Hospital, Denmark
    Acta Oncol 40:19-23. 2001
    ..In the future, the Society plans to expand this activity further...
  53. ncbi Different endoscopic surgical strategies in the management of inverted papilloma of the sinonasal tract: experience with 47 patients
    Davide Tomenzoli
    Department of Otorhinolaryngology, University of Brescia, Brescia, Italy
    Laryngoscope 114:193-200. 2004
    ..To demonstrate the potentials and limitations of three different endoscopic procedures employed for treatment of inverted papilloma (IP) of the sinonasal tract...
  54. ncbi Focal hyperostosis on CT of sinonasal inverted papilloma as a predictor of tumor origin
    D K Lee
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    AJNR Am J Neuroradiol 28:618-21. 2007
    ..To evaluate the CT characteristics of focal hyperostosis in patients with sinonasal inverted papilloma and to correlate these characteristics with the detection of the origins of tumors...
  55. ncbi Inverted papilloma: report of 89 cases
    Ernesto Pasquini
    Department of Otolaryngology, University of Bologna, Sant Orsola Malpighi Hospital, Italy
    Am J Otolaryngol 25:178-85. 2004
    ..In this study, the surgical management of an inverted papilloma of the nose and paranasal sinuses performed at our institution is reviewed...
  56. ncbi Chondromyxoid fibroma of the frontal sinus
    D Azorin
    Department of Pathology, Hospital Universitario 12 de Octubre, Madrid, Spain
    Br J Oral Maxillofac Surg 41:418-20. 2003
  57. ncbi Peripheral osteoma of the oral and maxillofacial region: a study of 35 new cases
    Nejat Bora Sayan
    Department of Oral and Maxillofacial Surgery, Dental Faculty, Ankara University, Ankara, Turkey
    J Oral Maxillofac Surg 60:1299-301. 2002
    ..The purpose of this article was to present 35 new cases of peripheral osteoma of the oral and maxillofacial region with an analysis of the literature...
  58. ncbi Common fibro-osseous lesions of the paranasal sinuses
    Robert Eller
    American Institute for Voice and Ear Care and The Graduate Institute, Philadelphia, PA, USA
    Otolaryngol Clin North Am 39:585-600, x. 2006
    ..They have similar appearance and makeup; however, their clinical implications vary. This article focuses primarily on sinonasal osteomas, with less emphasis on fibrous dysplasia and ossifying fibroma...
  59. ncbi Cancer of the nasal cavity and paranasal sinuses. A clinico-pathological study of 277 patients
    G Harbo
    Department of Head and Neck Surgery, Aarhus University Hospital, Denmark
    Acta Oncol 36:45-50. 1997
    ..poor 22%), primary T-site (nasal cavity 56% vs. maxillary antrum 39% vs. other sinuses 24%), tumour stage (T2 68% vs. T3 37% vs. T4 29%), nodal stage (N0 48% vs. N1-3 21%), treatment (radiotherapy + surgery 56% vs. radiation alone 35%)...
  60. ncbi Sinonasal chondromyxoid fibroma
    Emanuela F T Veras
    Department of Pathology, The University of Texas Medical School at Houston, Houston, Texas, USA
    Ann Diagn Pathol 13:41-6. 2009
    ..We believe that the use of SOX9 in our case assisted in the recognition of the chondroid nature of the lesion and facilitated the diagnosis of CMF...
  61. ncbi Patterns of failure after combined-modality approaches incorporating radiotherapy for sinonasal undifferentiated carcinoma of the head and neck
    Allen M Chen
    Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA, USA
    Int J Radiat Oncol Biol Phys 70:338-43. 2008
    ..To report the clinical outcome of patients treated with combined-modality approaches for sinonasal undifferentiated carcinoma (SNUC) of the head and neck...
  62. ncbi Lymph node metastases in malignant tumors of the paranasal sinuses: prognostic value and treatment
    Giulio Cantu
    National Cancer Institute, Via Venezian 1, 20133 Milano, Italy
    Arch Otolaryngol Head Neck Surg 134:170-7. 2008
    ..To assess the frequency of nodal involvement and its prognostic value in malignant tumors of the paranasal sinuses, particularly in maxillary sinus squamous cell carcinoma...
  63. ncbi Undifferentiated malignant neoplasms of the sinonasal tract
    Bruce M Wenig
    Department of Pathology and Laboratory Medicine, Beth Israel Medical Center, St Luke s Roosevelt Hospitals, New York, New York 10003, USA
    Arch Pathol Lab Med 133:699-712. 2009
    ..Nevertheless, differentiating these tumors has clinical import because advances in therapeutic intervention may increase survival with good quality of life, and in some instances may achieve a cure...
  64. ncbi Carcinomas of the paranasal sinuses and nasal cavity treated with radiotherapy at a single institution over five decades: are we making improvement?
    Allen M Chen
    Department of Radiation Oncology, University of California, San Francisco UCSF Comprehensive Cancer Center, San Francisco, CA, USA
    Int J Radiat Oncol Biol Phys 69:141-7. 2007
    ..To compare clinical outcomes of patients with carcinomas of the paranasal sinuses and nasal cavity according to decade of radiation treatment...
  65. ncbi Prognostic factors in sinonasal tumors involving the anterior skull base
    Carlos Suarez
    Department of Otolaryngology, Hospital Central de Asturias, Celestino Villaamil, S N, 33006 Oviedo, Spain
    Head Neck 26:136-44. 2004
    ..Anterior craniofacial resection is a standardized procedure for the treatment of ethmoid and frontal orbital tumors with intracranial invasion...
  66. ncbi Primary paranasal sinus lymphoma: natural history and improved outcome with central nervous system chemoprophylaxis
    Janessa J Laskin
    Division of Medical Oncology, University of British Columbia and the British Columbia Cancer Agency, Vancouver, BC, Canada
    Leuk Lymphoma 46:1721-7. 2005
    ..Treatment with combined modality chemotherapy and irradiation can cure many patients and the addition of intrathecal chemotherapy may reduce the risk of CNS relapse...
  67. ncbi Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses
    Megan E Daly
    Department of Radiation Oncology, University of California, San Francisco UCSF Comprehensive Cancer Center, San Francisco, CA, USA
    Int J Radiat Oncol Biol Phys 67:151-7. 2007
    ..To report the clinical outcome of patients treated with intensity-modulated radiation therapy (IMRT) for malignancies of the nasal cavity and paranasal sinuses...
  68. ncbi Postoperative intensity-modulated radiation therapy for cancers of the paranasal sinuses, nasal cavity, and lacrimal glands: technique, early outcomes, and toxicity
    Bradford S Hoppe
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, New York 10021, USA
    Head Neck 30:925-32. 2008
    ....
  69. ncbi Sphenoid sinus chondromyxoid fibroma mimicking a mucocele
    Stephen E Vernon
    Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA
    Am J Otolaryngol 27:406-8. 2006
    ..Although CMFs are generally regarded as benign neoplasms, they may show an infiltrative pattern and may recur, particularly when they are in locations where complete surgical excision may be difficult or impossible...
  70. ncbi Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting--the MSKCC experience
    Bradford S Hoppe
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 67:691-702. 2007
    ..To perform a retrospective analysis of patients with paranasal sinus (PNS) cancer treated with postoperative radiotherapy (RT) at Memorial Sloan-Kettering Cancer Center...
  71. ncbi Sinonasal neuroendocrine carcinoma: a case report
    Dulani Mendis
    Department of ENT Surgery, Queen s Hospital, Belvedere Rd, Burton upon Trent, Derby DE13 0RB, UK
    Ear Nose Throat J 87:280-2, 293. 2008
    ..The patient underwent a right lateral rhinotomy and medial maxillectomy followed by adjuvant radiotherapy. At 20 months of follow-up, he exhibited no sign of recurrence...
  72. ncbi Malignant tumors of the nasal cavity and paranasal sinuses
    Teri S Katz
    Department of Radiation Oncology, University of Florida Health Science Center, P O Box 100385, Gainesville, Florida 32610 0385, USA
    Head Neck 24:821-9. 2002
    ..To evaluate the role of radiation therapy in patients with nasal cavity and paranasal sinus tumors...
  73. ncbi Comparison of treatment plans using intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for paranasal sinus carcinoma
    David Huang
    Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA
    Int J Radiat Oncol Biol Phys 56:158-68. 2003
    ..To compare intensity-modulated radiotherapy (IMRT) treatment planning with three-dimensional conformal radiotherapy (3D-CRT) planning for paranasal sinus carcinoma...
  74. ncbi Radiotherapy after surgical resection for head and neck mucosal melanoma
    Abraham J Wu
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    Am J Clin Oncol 33:281-5. 2010
    ..To present our single-institution experience with postoperative radiotherapy for mucosal melanoma of the head and neck...
  75. ncbi Malignancies of the nasal cavity and paranasal sinuses: long-term outcome with conventional or three-dimensional conformal radiotherapy
    Piet Dirix
    Department of Radiation Oncology, Leuvens Kanker Instituut, University Hospital Gasthuisberg, Leuven, Belgium
    Int J Radiat Oncol Biol Phys 69:1042-50. 2007
    ..To evaluate the long-term clinical outcome and toxicity of conventional and three-dimensional conformal radiotherapy for malignancies of the nasal cavity and paranasal sinuses...
  76. ncbi Sinonasal tubulopapillary low-grade adenocarcinoma. Histopathological, immunohistochemical and ultrastructural features of poorly recognised entity
    A Skalova
    Medical Faculty Hospital, Charles University, Alej Svobody 80, 323 18 Plzen, Czech Republic
    Virchows Arch 443:152-8. 2003
    ....
  77. ncbi Low-grade salivary type tubulo-papillary adenocarcinoma of the sinonasal tract
    A Franchi
    Histopathology 48:881-4. 2006
  78. ncbi Does the combination of radiotherapy and debulking surgery favor survival in paranasal sinus carcinoma?
    E P Jansen
    Department of Radiation Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 48:27-35. 2000
    ..As most patients present with locally advanced disease, the possibility of radical surgery is limited. Consequently, radiotherapy is often needed as monotherapy or as an adjunct to surgery...
  79. ncbi Occupational risks for adenocarcinoma of the nasal cavity and paranasal sinuses in the German wood industry
    B Pesch
    BGFA Forschungsinstitut für Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung, Burkle de la Camp Platz 1, 44789 Bochum, Germany
    Occup Environ Med 65:191-6. 2008
    ..To examine the risk of wood dust and chemical exposures for adenocarcinoma of the nasal cavity and paranasal sinuses (ADCN) among German wood workers...
  80. ncbi Comparative genomic hybridization in primary sinonasal adenocarcinomas
    Manuela Ariza
    Instituto Universitario de Oncologia del Principado de Asturias, University of Oviedo, JM Caso 14, 33006 Oviedo, Asturias, Spain
    Cancer 100:335-41. 2004
    ..The goal of the current study was to detect recurrent chromosomal gains and losses in a series of 21 primary sinonasal adenocarcinomas using comparative genomic hybridization (CGH)...
  81. ncbi Sino-nasal cancer and exposure to leather dust
    Vincent Bonneterre
    Laboratoire EPSP TIMC, UMR CNRS 5525, Faculte de Medecine, Domaine de la Merci, 38700 La Tronche Cedex, France
    Occup Med (Lond) 57:438-43. 2007
    ..However, there are 10 times fewer articles published on Medline compared to wood dust which also induces sino-nasal cancer...
  82. ncbi Report of a study on IMRT planning strategies for ethmoid sinus cancer
    Filip Claus
    Division of Radiotherapy, Ghent University Hospital, Belgium
    Strahlenther Onkol 178:572-6. 2002
    ..This communication reviews the planning strategies and dose statistics of nine IMRT plans generated for a complex head and neck case...
  83. pmc COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure
    Reetta Holmila
    Finnish Institute of Occupational Health, Helsinki, Finland
    Int J Cancer 122:2154-9. 2008
    ..In contrast, SCCs predominated among smokers and expressed COX-2 rarely; this may suggest at least partially different molecular mechanisms...
  84. ncbi Sinonasal cancer and occupational exposures: a pooled analysis of 12 case-control studies
    Daniele Luce
    INSERM Unité 88, Hopital, National de Saint Maurice, Saint Maurice, France
    Cancer Causes Control 13:147-57. 2002
    ..In order to examine the associations between sinonasal cancer and occupational exposures other than wood dust and leather dust, the data from 12 case-control studies conducted in seven countries were pooled and reanalyzed...
  85. ncbi Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia
    K Innos
    Department of Epidemiology and Biostatistics, Institute of Experimental and Clinical Medicine, Tallinn, Estonia
    Am J Ind Med 37:501-11. 2000
    ..Occupational wood dust exposure is associated with increased risk of sinonasal cancer in men. However, little is known whether it is associated with sinonasal cancer in women or with malignancies of other sites...
  86. ncbi Chromosomal imbalances in wood dust-related adenocarcinomas of the inner nose and their associations with pathological parameters
    Dirk Korinth
    Institute of Pathology, University Hospital Charite, Berlin, Germany
    J Pathol 207:207-15. 2005
    ..These data provide further evidence for a recurrent pattern of chromosomal imbalances in sinonasal adenocarcinomas and highlight distinct aberrations that are associated with tumour differentiation and progression...
  87. ncbi Infantile fibromatosis of the nose and paranasal sinuses: report of a rare case and brief review of the literature
    Abul Ala Syed Rifat Mannan
    Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
    Ear Nose Throat J 83:481-4. 2004
    ..We also discuss the clinicopathologic features of this lesion, including its ultrastructural characteristics, and we review the literature...
  88. ncbi Genome-wide analysis of genetic changes in intestinal-type sinonasal adenocarcinoma
    Mario A Hermsen
    Department of Otorhinolaryngology, IUOPA, Hospital Universitario Central de Asturias, Asturias, Spain
    Head Neck 31:290-7. 2009
    ..Intestinal-type sinonasal adenocarcinomas are rare tumors related to professional exposure to wood dust. Little is known about the genetic changes in these tumors...
  89. ncbi Primary sphenoid sinus neoplasms: a report of four cases with common clinical presentation treated with transsphenoidal surgery and adjuvant therapies
    Felice Esposito
    Department of Surgery, Division of Neurosurgery, David Geffen School of Medicine, University of California Los Angeles UCLA Medical Center, Los Angeles, California 90095 7182, USA
    J Neurooncol 76:299-306. 2006
    ..Primary neoplasms of the sphenoid sinus are a rare occurrence, accounting for approximately 1-2% of all paranasal sinus tumors. Here we report a series of four such patients...
  90. ncbi Routine histopathology in uncomplicated sinus surgery: is it necessary?
    Alexander A Romashko
    Department of Otolaryngology Head and Neck Surgery, Loyola University Medical Center, Maywood, IL, USA
    Otolaryngol Head Neck Surg 132:407-12; discussion 413. 2005
    ..To evaluate the incidence of occult pathology in routine, uncomplicated endoscopic sinus surgery, and to suggest guidelines for when to send specimens for histopathologic exam...
  91. ncbi Adenocarcinomas of the nasal cavity and paranasal sinuses: a clinicopathological and immunohistochemical study of 14 cases
    J Abecasis
    Serviço Universitário de Anatomia Patológica, Faculdade de Ciencias Medicas, Universidade Nova de Lisboa, Lisboa, Portugal
    Histopathology 45:254-9. 2004
    ....
  92. ncbi [Sphenoid sinus lymphoma. Case report and review of the literature]
    P Metellus
    Service de Neurochirurgie, Hopital de la Timone, Marseille
    Neurochirurgie 48:522-6. 2002
    ..This case underscores the importance of thorough radiological work-up for accurate identification of tumor masses involving the pituitary fossa and provides an opportunity to review the literature on the management of this rare entity...
  93. ncbi Postoperative intensity-modulated radiotherapy in sinonasal carcinoma: clinical results in 39 patients
    Wim Duthoy
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Cancer 104:71-82. 2005
    ..Intensity-modulated radiotherapy (IMRT) is a relatively new technique, which is implemented with the hypothesis that, compared with conventional RT, it would result in a lower rate of ocular toxicity for an equal local control (LC)...
  94. ncbi Case-control study evaluating the homogeneity and heterogeneity of risk factors between sinonasal and nasopharyngeal cancers
    Kangmin Zhu
    Department of Health Evaluation Sciences, Penn State College of Medicine, Hershey, PA 17033 0855, USA
    Int J Cancer 99:119-23. 2002
    ..Our study suggests that except for smoking and chlorophenol exposure, which are associated with both sites, the risk factor profiles may differ between sinonasal and nasopharyngeal cancers...
  95. ncbi Postoperative radiotherapy for adenocarcinoma of the ethmoid sinuses: treatment results for 47 patients
    Filip Claus
    Division of Radiotherapy P7, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Int J Radiat Oncol Biol Phys 54:1089-94. 2002
    ..This study reports on the treatment outcome of 47 patients diagnosed with adenocarcinoma of the ethmoid sinuses and treated with surgery and high-dose postoperative radiation therapy...
  96. ncbi Non-coplanar beam direction optimization for intensity-modulated radiotherapy
    G Meedt
    Department of Medical Physics, Universitatsklinikum Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Phys Med Biol 48:2999-3019. 2003
    ..The existence of a threshold number for the minimum configuration and its dependence on the complexity of the problem are shown. BDO outperforms manual configurations and equispaced coplanar beam arrangements in both example cases...
  97. ncbi Short term toxicity profile for 32 sinonasal cancer patients treated with IMRT. Can we avoid dry eye syndrome?
    Filip Claus
    Division of Radiotherapy P7, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Radiother Oncol 64:205-8. 2002
    ..Follow-up it too short to evaluate local control, optic nerve or retinal toxicity...
  98. ncbi Genetic and clinical aspects of wood dust related intestinal-type sinonasal adenocarcinoma: a review
    Jose Luis Llorente
    Department of Otolaryngology, Instituto Universitario de Oncologia del Principado de Asturias, Edificio H Covadonga 1 feminine Planta Centro, Lab 2, Hospital Universitario Central de Asturias, Celestino Villamil s n, 33006, Oviedo, Spain
    Eur Arch Otorhinolaryngol 266:1-7. 2009
    ..This review aims to describe the clinico-pathological characteristics of this relatively unknown tumor and to summarize the knowledge on genetic and chromosomal analyses up to the present time...
  99. ncbi Inverted papilloma of paranasal sinuses
    Georg Eggers
    Department of Oral and Cranio Maxillofacial Surgery, Heidelberg University Hospital, Heidelberg, Germany
    J Craniomaxillofac Surg 35:21-9. 2007
    ..Clinical problems include a tendency towards local destruction, recurrence and malignant transformation into squamous cell carcinoma. Hence, complete surgical removal is the therapy of choice and a meticulous follow-up is mandatory...
  100. ncbi Meningioma of the paranasal sinus: a case report
    Kazuyuki Kainuma
    Department of Otolaryngology, Shinshu University School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    Auris Nasus Larynx 34:397-400. 2007
    ..This is the first report of the use of such a system with endoscopic surgery for this condition. We discuss the clinical presentation, diagnosis, and treatment of this case as well as present a review of the literature...
  101. ncbi Cavernous hemangioma involving the lacrimal outflow system
    Anna S Kitzmann
    Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA
    Ophthal Plast Reconstr Surg 23:488-90. 2007
    ..Histopathology revealed a cavernous hemangioma involving the nasolacrimal duct and nasal cavity. Cavernous hemangiomas may occur rarely in the nasal cavity, paranasal sinuses, and/or the nasolacrimal duct...

Research Grants3

  1. Cytokines on Olfactory Receptor Neuron Function
    Andrew Lane; Fiscal Year: 2006
    ..Additional bench research will be performed in the laboratory of Dr. Schleimer, an established scientist with expertise in airway inflammation and cytokine modulation of cell function. ..
  2. Human Copper Transporter 1 as Reporter Gene for Imaging
    Fangyu Peng; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  3. A Novel Tool to Understand Insulin Production and Failure in Pancreatic beta-Cell
    Israel Hodish; Fiscal Year: 2008
    ..The model presented opens new avenues to the development and testing of potential therapeutic interventions that may ultimately help preserve insulin secretory function in humans with diabetes mellitus. [unreadable] [unreadable]..