vestibular diseases

Summary

Summary: Diseases of the vestibule, the part of the inner ear that contains organs involved with balance.

Top Publications

  1. ncbi Closing an open-loop control system: vestibular substitution through the tongue
    Mitchell Tyler
    Wicab, Inc, 3510 W Beltline Hwy, Middleton, WI 53562, USA
    J Integr Neurosci 2:159-64. 2003
  2. pmc Cell phone based balance trainer
    Beom Chan Lee
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, USA
    J Neuroeng Rehabil 9:10. 2012
  3. ncbi Impulsive testing of semicircular-canal function using video-oculography
    Konrad P Weber
    Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia
    Ann N Y Acad Sci 1164:486-91. 2009
  4. pmc Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome
    Damien Lederer
    Centre de Genetique Humaine, Institut de Pathologie et Genetique, Charleroi, Belgium
    Am J Hum Genet 90:119-24. 2012
  5. ncbi Acrophobia and pathological height vertigo: indications for vestibular physical therapy?
    Susan L Whitney
    Department of Physical Therapy, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 85:443-58. 2005
  6. ncbi Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades
    K P Weber
    Neurology Department, Royal Prince Alfred Hospital, Camperdown NSW 2050, Sydney, Australia
    Neurology 70:454-63. 2008
  7. pmc The video head impulse test: diagnostic accuracy in peripheral vestibulopathy
    H G MacDougall
    Vestibular Research Laboratory, School of Psychology, University of Sydney, Sydney, Australia
    Neurology 73:1134-41. 2009
  8. ncbi Audio-biofeedback improves balance in patients with bilateral vestibular loss
    Marco Dozza
    Department of Electronics, Computer Science and Systems, University of Bologna, Bologna, Italy
    Arch Phys Med Rehabil 86:1401-3. 2005
  9. ncbi Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound
    S M Rosengren
    Institute of Neurological Sciences and UNSW Clinical School, Prince of Wales Hospital Randwick, Sydney, NSW 2031, Australia
    Clin Neurophysiol 116:1938-48. 2005
  10. pmc Mutation spectrum of MLL2 in a cohort of Kabuki syndrome patients
    Lucia Micale
    Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, 71013 San Giovanni Rotondo, Italy
    Orphanet J Rare Dis 6:38. 2011

Research Grants

  1. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2005
  2. CONDITIONAL GENE TARGETING IN HAIR CELLS
    Jian Zuo; Fiscal Year: 2003
  3. VIRTUAL REALITY IN BALANCE DISORDERS
    Susan Whitney; Fiscal Year: 2007
  4. MANAGEMENT OF ADAPTATION TO ALTERED SENSORIMOTOR STATES
    Helen Cohen; Fiscal Year: 2003
  5. TREATMENTS FOR BENIGN PAROXYSMAL POSITIONAL VERTIGO
    Helen Cohen; Fiscal Year: 2008
  6. RECOVERY OF VISUAL ACUITY IN VESTIBULAR DEFICITS
    SUSAN HERDMAN; Fiscal Year: 2002
  7. CERVICAL INFLUENCES ON BALANCE
    Joseph Furman; Fiscal Year: 2003
  8. VESTIBULO-OCULAR FUNCTION IN THE ELDERLY
    Joseph Furman; Fiscal Year: 2009
  9. International Conference on Episodic Ataxia Syndromes
    Joanna Jen; Fiscal Year: 2005
  10. Genetics of Familial Episodic Ataxia
    Joanna C Jen; Fiscal Year: 2010

Detail Information

Publications245 found, 100 shown here

  1. ncbi Closing an open-loop control system: vestibular substitution through the tongue
    Mitchell Tyler
    Wicab, Inc, 3510 W Beltline Hwy, Middleton, WI 53562, USA
    J Integr Neurosci 2:159-64. 2003
    ..Moreover, postural stability persists for a period of time after removing the vestibular substitution, after which the open-loop instability reappears...
  2. pmc Cell phone based balance trainer
    Beom Chan Lee
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, USA
    J Neuroeng Rehabil 9:10. 2012
    ....
  3. ncbi Impulsive testing of semicircular-canal function using video-oculography
    Konrad P Weber
    Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia
    Ann N Y Acad Sci 1164:486-91. 2009
    ..This system is easy to use in a clinical setting, provides an objective measure of the vestibulo-ocular reflex (VOR), and detects both overt and covert catch-up saccades in patients with vestibular loss...
  4. pmc Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome
    Damien Lederer
    Centre de Genetique Humaine, Institut de Pathologie et Genetique, Charleroi, Belgium
    Am J Hum Genet 90:119-24. 2012
    ..This study identifies KDM6A mutations as another cause of KS and highlights the growing role of histone methylases and histone demethylases in multiple-congenital-anomaly and intellectual-disability syndromes...
  5. ncbi Acrophobia and pathological height vertigo: indications for vestibular physical therapy?
    Susan L Whitney
    Department of Physical Therapy, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 85:443-58. 2005
    ..The purpose of this case report is to describe the use of vestibular physical therapy intervention following behavioral therapy to reduce a patient's visual dependence and height vertigo...
  6. ncbi Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades
    K P Weber
    Neurology Department, Royal Prince Alfred Hospital, Camperdown NSW 2050, Sydney, Australia
    Neurology 70:454-63. 2008
    ..Bedside HIT identifies subsequent catch-up saccades after the head rotation as indirect signs of VOR deficit...
  7. pmc The video head impulse test: diagnostic accuracy in peripheral vestibulopathy
    H G MacDougall
    Vestibular Research Laboratory, School of Psychology, University of Sydney, Sydney, Australia
    Neurology 73:1134-41. 2009
    ..The scleral search coil technique is the gold standard for HIT measurements, but it is not practical for routine testing or for acute patients, because they are required to wear an uncomfortable contact lens...
  8. ncbi Audio-biofeedback improves balance in patients with bilateral vestibular loss
    Marco Dozza
    Department of Electronics, Computer Science and Systems, University of Bologna, Bologna, Italy
    Arch Phys Med Rehabil 86:1401-3. 2005
    ..To evaluate the effectiveness of an audio-biofeedback (ABF) system for improving balance in patients with bilateral vestibular loss (BVL)...
  9. ncbi Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound
    S M Rosengren
    Institute of Neurological Sciences and UNSW Clinical School, Prince of Wales Hospital Randwick, Sydney, NSW 2031, Australia
    Clin Neurophysiol 116:1938-48. 2005
    ..To investigate the origin, whether ocular or extraocular, of the short latency frontal potential (N15) reported by following vestibular stimulation...
  10. pmc Mutation spectrum of MLL2 in a cohort of Kabuki syndrome patients
    Lucia Micale
    Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, 71013 San Giovanni Rotondo, Italy
    Orphanet J Rare Dis 6:38. 2011
    ..Recently mutations in the histone methyl transferase MLL2 gene have been identified as its underlying cause...
  11. ncbi Observation of vestibular asymmetry in a majority of patients over 50 years with fall-related wrist fractures
    E K Kristinsdottir
    Department of Otorhinolaryngology, Lund University, Sweden
    Acta Otolaryngol 121:481-5. 2001
    ..These findings suggest that an asymmetric vestibular function could be an epidemiologically important contributory factor to falls and wrist fractures among the elderly population...
  12. ncbi Vestibular and proprioceptive influences on trunk movements during quiet standing
    C G C Horlings
    Radboud University Nijmegen Medical Center, Donders Institute for Brain, Cognition and Behaviour, Departments of Neurology, The Netherlands
    Neuroscience 161:904-14. 2009
    ..We conclude that there is relative motion between the upper trunk and pelvis during quiet stance and suggest that it may contribute to balance control...
  13. ncbi Effects of multi-directional vibrotactile feedback on vestibular-deficient postural performance during continuous multi-directional support surface perturbations
    K H Sienko
    Division of Health Sciences and Technology, Harvard Massachusetts Institute of Technology, Cambridge, MA, USA
    J Vestib Res 18:273-85. 2008
    ..Therefore, a spatial resolution of 90 degrees (4 columns) seems to be as effective as a spatial resolution of 22.5 degrees (16 columns) for control of standing...
  14. ncbi Vestibular dysfunction in vitamin D receptor mutant mice
    Anna Minasyan
    Department of Anatomy, Medical School, University of Tampere, Finland
    J Steroid Biochem Mol Biol 114:161-6. 2009
    ..These data suggest that VDR deficiency in mice is associated with decreased balance function, and may be relevant to poorer balance/posture control in humans with low levels of vitamin D...
  15. ncbi Disorders of balance and vestibular function in US adults: data from the National Health and Nutrition Examination Survey, 2001-2004
    Yuri Agrawal
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA
    Arch Intern Med 169:938-44. 2009
    ....
  16. ncbi Horizontal head impulse test detects gentamicin vestibulotoxicity
    K P Weber
    Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia
    Neurology 72:1417-24. 2009
    ..Parenteral antibiotic therapy with gentamicin, even in accepted therapeutic doses, can occasionally cause bilateral vestibular loss (BVL) due to hair cell toxicity...
  17. ncbi Large vestibular aqueduct syndrome: audiological, radiological, clinical, and genetic features
    Stefano Berrettini
    ENT Unit, Neuroscience Department, University of Pisa, 56126 Pisa, Italy
    Am J Otolaryngol 26:363-71. 2005
    ..The aim of this study was to analyze the clinical, audiological, radiological, and genetic features of a group of patients affected with large vestibular aqueduct syndrome...
  18. ncbi Older adults and balance dysfunction
    Gregory F Marchetti
    Department of Physical Therapy, Rangos School of Health Sciences, Duquesne University, Pittsburgh, PA, USA
    Neurol Clin 23:785-805, vii. 2005
  19. ncbi Effect of vestibular rehabilitation on dizziness in the elderly
    Jae Yun Jung
    Department of Otolaryngology Head and Neck Surgery, Dankook University College of Medicine, Cheonan City, Chungnam do 330 714, South Korea
    Am J Otolaryngol 30:295-9. 2009
    ..Dizziness in the elderly is relatively common, but only a few studies are available. The purpose of this study was to analyze the effect of vestibular rehabilitation on dizziness in elderly patients...
  20. ncbi Comparison of head thrust test with head autorotation test reveals that the vestibulo-ocular reflex is enhanced during voluntary head movements
    Charles C Della Santina
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins Medical Institutions, 601 N Caroline St, Baltimore, MD 21287 0910, USA
    Arch Otolaryngol Head Neck Surg 128:1044-54. 2002
    ....
  21. ncbi Walking performance of vestibular-defective patients before and after unilateral vestibular neurotomy
    Liliane Borel
    UMR 6149, Neurobiologie Intégrative et Adaptative, Universite de Provence CNRS, 52, Faculte de St Jerome, Case 361, 13397 Marseille Cedex 20, France
    Behav Brain Res 150:191-200. 2004
    ..They argue for an increased weight of visual reference frame on locomotor functions when vestibular function is unilaterally impaired...
  22. ncbi Increased independence and decreased vertigo after vestibular rehabilitation
    Helen S Cohen
    Bobby R Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX 77030, USA
    Otolaryngol Head Neck Surg 128:60-70. 2003
    ..We sought to determine the effectiveness in decreasing some symptoms, such as vertigo, and increasing performance of daily life skills after vestibular rehabilitation...
  23. ncbi Differences in coding provided by proprioceptive and vestibular sensory signals may contribute to lateral instability in vestibular loss subjects
    John H J Allum
    Department of ORL, University Hospital, Basel, Switzerland
    Exp Brain Res 184:391-410. 2008
    ....
  24. pmc Vibrotactile biofeedback improves tandem gait in patients with unilateral vestibular loss
    Fay B Horak
    Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA
    Ann N Y Acad Sci 1164:279-81. 2009
    ..However, BF did not increase the rate of improvement or retention of improved stability during gait...
  25. ncbi Downbeat nystagmus: aetiology and comorbidity in 117 patients
    J N Wagner
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, D 81366 Munich, Germany
    J Neurol Neurosurg Psychiatry 79:672-7. 2008
    ..We reviewed 117 patients to establish whether analysis of a large collective and improved diagnostic means would reduce the number of cases with "idiopathic DBN" and thus change the aetiological spectrum...
  26. pmc A mathematical model of human semicircular canal geometry: a new basis for interpreting vestibular physiology
    Andrew P Bradshaw
    School of Electrical Engineering, The University of New South Wales, Sydney, Australia
    J Assoc Res Otolaryngol 11:145-59. 2010
    ..Finally, we mathematically model SCC geometry using Fourier series equations. This work has the potential to reinterpret physiology and pathophysiology in terms of real individual 3D morphology...
  27. ncbi Assessment of vibrotactile feedback on postural stability during pseudorandom multidirectional platform motion
    Kathleen H Sienko
    Department ofMechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
    IEEE Trans Biomed Eng 57:944-52. 2010
    ..However, the spatial resolution of the tactor displays did not affect subjects' performance, thereby supporting the use of a lower spatial resolution display in future device designs...
  28. ncbi Effectiveness of head-mounted vibrotactile stimulation in subjects with bilateral vestibular loss: a phase 1 clinical trial
    Joel A Goebel
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Otol Neurotol 30:210-6. 2009
    ..Evaluate the effectiveness of a head-mounted vibrotactile prosthesis for balance improvement in subjects with severe bilateral vestibular loss (BVL)...
  29. ncbi Vestibulo-ocular physiology underlying vestibular hypofunction
    Michael C Schubert
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, 710 Ross Bldg, 720 Rutland Ave, Baltimore, MD 21205, USA
    Phys Ther 84:373-85. 2004
    ..The purposes of this article are to review the anatomy and physiology of the vestibular system and to describe the neurophysiological mechanisms responsible for the vestibulo-ocular abnormalities in patients with vestibular hypofunction...
  30. ncbi The challenges of managing vestibular disorders: a qualitative study of clinicians' experiences associated with low referral rates for vestibular rehabilitation
    S H Polensek
    Rehabilitation Research and Development, Atlanta VA Medical Center, Decatur, GA, USA
    Int J Clin Pract 63:1604-12. 2009
    ..To explore clinicians' perspectives influencing the under-diagnosis and management of patients with vestibular impairment (VI)...
  31. ncbi A balance control model predicts how vestibular loss subjects benefit from a vibrotactile balance prosthesis
    Adam D Goodworth
    Center for Health, CARE, and Well being, Department of Physical Therapy, University of Hartford, West Hartford, CT 06117, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:1306-9. 2011
    ....
  32. ncbi Can Tai Chi improve vestibulopathic postural control?
    Peter M Wayne
    Research Department, New England School of Acupuncture, Watertown, MA 02472, USA
    Arch Phys Med Rehabil 85:142-52. 2004
    ..To evaluate the rationale and scientific support for Tai Chi as an intervention for vestibulopathy and to offer recommendations for future studies...
  33. ncbi Effect of displacement, velocity, and combined vibrotactile tilt feedback on postural control of vestibulopathic subjects
    C Wall
    Department of Otology and Laryngology and Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    J Vestib Res 20:61-9. 2010
    ..The improvement by using a predictor is consistent with compensating for a neural processing delay...
  34. ncbi Tailchaser (Tlc): a new mouse mutation affecting hair bundle differentiation and hair cell survival
    A E Kiernan
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    J Neurocytol 28:969-85. 1999
    ..Based on the mode of inheritance and map location, Tlc appears to be a novel mouse mutation affecting both hair cell survival and stereocilia bundle development...
  35. ncbi The balance control of bilateral peripheral vestibular loss subjects and its improvement with auditory prosthetic feedback
    J Hegeman
    Department of ORL, University Hospital, Basel, Switzerland
    J Vestib Res 15:109-17. 2005
    ..A successful integration of natural and artificial signals would provide a basis for a balance prosthesis...
  36. ncbi [Disability due to auditory and vestibular dysfunction in a specialized care center]
    Aralia Gutiérrez-Márquez
    Departamento de Audiología y Otoneurología del HG GGG CMN La Raza IMSS
    Gac Med Mex 141:105-10. 2005
    ..To assess the frequency and characteristics of the disability associated with hearing loss and vestibular disease in a Specialized Medical Center of the Mexican Social Security Institute...
  37. ncbi Designing vibrotactile balance feedback for desired body sway reductions
    Patrick Loughlin
    University of Pittsburgh, Pittsburgh, PA 15261, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:1310-3. 2011
    ..Simulation results are provided to illustrate the results...
  38. ncbi The sensitivity and specificity of the Timed "Up & Go" and the Dynamic Gait Index for self-reported falls in persons with vestibular disorders
    Susan L Whitney
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    J Vestib Res 14:397-409. 2004
    ..Slower scores on the TUG (> 11.1 seconds) and lower scores on the DGI (18) correlated with reports of falls in persons with vestibular dysfunction...
  39. ncbi The effect of age on vestibular rehabilitation outcomes
    Susan L Whitney
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Laryngoscope 112:1785-90. 2002
    ..The purpose of the retrospective chart review was to compare vestibular rehabilitation outcomes in young versus older adults...
  40. ncbi Improving impaired balance function: real-time versus carry-over effects of prosthetic feedback
    John H J Allum
    Dept of ORL, University Hospital of Basel, Switzerland
    Conf Proc IEEE Eng Med Biol Soc 2011:1314-8. 2011
    ..However, the prospect for longer term (>1 week) effects of prosthetic training on balance control remains currently unknown...
  41. ncbi Partial anomalous left pulmonary artery along with aortic coarctation in an infant with Kabuki syndrome
    Aarti H Bhat
    Division of Pediatric Cardiology, Seattle Children s Hospital, University of Washington, Seattle, Washington 98105, USA
    Echocardiography 29:E145-7. 2012
    ..While coarctation and hypoplastic left heart syndrome are observed in this syndrome, this is the second reported case of aLPA in KS and the first with the forme fruste of left-sided obstruction as well as aLPA in this group of patients...
  42. ncbi Chronological changes of hearing in pediatric patients with large vestibular aqueduct syndrome
    Chien Chung Lai
    Department of Otolaryngology, National Yang Ming University, Taipei, Taiwan, Republic of China
    Laryngoscope 114:832-8. 2004
    ..To describe the chronologic changes of hearing in patients with large vestibular aqueduct syndrome (LVAS) and identify the prognostic factors...
  43. ncbi Determining the preferred modality for real-time biofeedback during balance training
    Kelli E Bechly
    Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, United States
    Gait Posture 37:391-6. 2013
    ....
  44. ncbi Assessing the effect of vibrotactile feedback during continuous multidirectional platform motion: a frequency domain approach
    V V Vichare
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6910-3. 2009
    ..3 Hz. The lack of a consistent difference among tactor configurations argue in favor of the simplest 4-column configuration during multidirectional continuous surface perturbations...
  45. ncbi Using vibrotactile feedback of instability to trigger a forward compensatory stepping response
    Francois Asseman
    Imperial College London, Department of Clinical Neuroscience, Charing Cross Campus, Fulham Palace Road, London W6 8RF, UK
    J Neurol 254:1555-61. 2007
    ..We conclude that the effectiveness of vibration biofeedback appears limited. Any enhancement of compensatory stepping might be triggered by speeding the decision to step rather than by creating a specific stimulus-response loop...
  46. ncbi Determining subjective visual vertical: dynamic versus static testing
    Mario Faralli
    Otolaryngology and Cervicofacial Surgery Division, Department of Medical Surgical Specialization, University of Perugia, Perugia, Italy
    Otol Neurotol 28:1069-71. 2007
    ....
  47. ncbi Unilateral examination of utricle and saccule function
    A H Clarke
    Vestibular Research Laboratory, HNO Klinik, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, 12200 Berlin, Germary
    J Vestib Res 13:215-25. 2003
    ..To illustrate the efficacy of such differential testing, the findings from two patients are presented that demonstrate for the first time an isolated unilateral utricular dysfunction...
  48. ncbi Vestibular rehabilitation by auditory feedback in otolith disorders
    Dietmar Basta
    Department Otolaryngology at ukb, Hospital of the University of Berlin, Warener Str 7, 12683 Berlin, Germany
    Gait Posture 28:397-404. 2008
    ..The results indicate that an auditory feedback rehabilitation program with exercises related to the specific neurotological disease could significantly improve the postural control in patients with otolith disorders...
  49. ncbi Otoneurological findings in human immunodeficiency virus positive patients
    R Teggi
    Department of ENT, Istitudo di Ricovero e Cura a Carattere Scientifico San Raffaele Hospital, Vita Salute University, Milan, Italy
    J Laryngol Otol 122:1289-94. 2008
    ..To investigate vestibular function in human immunodeficiency virus positive subjects...
  50. ncbi Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation
    Henry Pau
    MRC Institute of Hearing Research, University Park, Nottingham, UK
    Otol Neurotol 25:707-13. 2004
    ..Furthermore, we asked whether the mutation responsible for the defects was located in the same region of mouse chromosome 4 as several other mouse mutations that we have previously described...
  51. ncbi Vestibular rehabilitation with electrotactile vestibular substitution: early effects
    Alev Uneri
    Department of Otorhinolaryngology, Balance Center, Acibadem Oncology and Neurology Hospital, Istanbul, Turkey
    Eur Arch Otorhinolaryngol 266:1199-203. 2009
    ..In conclusion, these preliminary results demonstrate efficacy of the EVSS in improving patients symptoms and signs and signify the evidence of sensory substitution in the early post-training period...
  52. pmc Vestibular function in HIV patients: preliminary report
    R Teggi
    Deparment of ENT, IRRCS S Raffaele Hospital, Milan, Italy
    Acta Otorhinolaryngol Ital 26:140-6. 2006
    ..In order to evaluate equilibrium in these patients, a Dynamic Gait Index (DGI) test was performed. Scores were >21 points in 85.7% of Class A patients and decreased in Classes B and C...
  53. ncbi Vestibular function testing
    E E Lang
    Department of Otolaryngology Head and Neck Surgery, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland
    Ir J Med Sci 179:173-8. 2010
    ..However, in a subgroup of patients, vestibular function testing may be invaluable in arriving at a correct diagnosis and ultimately in the optimal treatment of these patients...
  54. ncbi Systematic review of vestibular disorders related to human immunodeficiency virus and acquired immunodeficiency syndrome
    B Heinze
    Department of Communication Pathology, University of Pretoria, Pretoria, South Africa
    J Laryngol Otol 125:881-90. 2011
    ..Disorders of the auditory and vestibular system are often associated with human immunodeficiency virus infection and acquired immunodeficiency syndrome. However, the extent and nature of these vestibular manifestations are unclear...
  55. ncbi The interpretation of clinical tests of peripheral vestibular function
    Ian S Curthoys
    Vestibular Research Laboratory, School of Psychology, University of Sydney, Sydney, New South Wales, Australia
    Laryngoscope 122:1342-52. 2012
    ....
  56. ncbi The reliability and validity of the Four Square Step Test for people with balance deficits secondary to a vestibular disorder
    Susan L Whitney
    Department of Physical Therapy, University of Pittsburgh School of Health and Rehabilitation Sciences, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 88:99-104. 2007
    ..To determine the reliability and validity of the Four Square Step Test (FSST) for use in people with balance deficits secondary to vestibular disorders, who frequently report falling and have difficulty with changes of direction...
  57. ncbi A systematic review about the effects of the vestibular rehabilitation in middle-age and older adults
    Natalia A Ricci
    Departamento de Fisioterapia, Universidade Federal de Sao Carlos, Sao Carlos, SP, Brasil
    Rev Bras Fisioter 14:361-71. 2010
    ..to summarize the results of clinical trials on vestibular rehabilitation (VR) in middle-aged and elderly people with vestibular disorders...
  58. pmc Influence of extero- and proprioceptive afferents of the plantar surface in determining subjective visual vertical in patients with unilateral vestibular dysfunction
    M Faralli
    Otolaryngology and Cervicofacial Surgery Clinic, University of Perugia, via delle Danaidi 21, Perugia, Italy
    Acta Otorhinolaryngol Ital 29:245-50. 2009
    ....
  59. ncbi Dynamic and static subjective visual vertical with aging
    Hironari Kobayashi
    Department of Otorhinolaryngology, School of Medicine, Keio University, 35 Shinanomachi Shin juku, 160 8582, Tokyo, Japan
    Auris Nasus Larynx 29:325-8. 2002
    ..Our vestibular function is gradually deteriorating during aging, although, its behavioral consequences are not easily recognized due to a substitution process by other sensory modalities as visual or proprioceptive inputs...
  60. ncbi The influence of footwear on timed balance scores of the modified clinical test of sensory interaction and balance
    Susan L Whitney
    Department of Physical Therapy, Univesity of Pittsburgh, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 85:439-43. 2004
    ....
  61. ncbi Driving disability and dizziness
    Helen S Cohen
    Bobby R Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA
    J Safety Res 34:361-9. 2003
    ..e., inner ear) disorders complain of difficulty driving. Physicians occasionally warn their patients with vestibular disorders not to drive. Few studies have asked patients about their driving performance, so little data are available...
  62. ncbi Recovery of dynamic visual acuity in unilateral vestibular hypofunction
    Susan J Herdman
    Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA
    Arch Otolaryngol Head Neck Surg 129:819-24. 2003
    ..To determine the effect of vestibular exercises on the recovery of visual acuity during head movement in patients with unilateral vestibular hypofunction...
  63. ncbi Head taps evoke a crossed vestibulo-ocular reflex
    S Iwasaki
    Vestibular Research Laboratory, School of Psychology, University of Sydney, Sydney, NSW, Australia
    Neurology 68:1227-9. 2007
    ..These responses probably reflect vestibular function via crossed otolith-ocular pathways...
  64. ncbi Characteristics and clinical applications of vestibular-evoked myogenic potentials
    Miriam S Welgampola
    Institute of Neurological Sciences, Prince of Wales Hospital and School of Medicine, University of New South Wales, Sydney, Australia
    Neurology 64:1682-8. 2005
    ....
  65. pmc A systematic review of vertigo in primary care
    K Hanley
    Trinity College, Dublin, Ireland
    Br J Gen Pract 51:666-71. 2001
    ..An important practice point is that vestibular sedatives are not recommended on a prolonged basis for any type of vertigo. There is a need for basic epidemiological and clinical management research of vertigo in general practice...
  66. ncbi Repair of the vestibular system via adenovector delivery of Atoh1: a potential treatment for balance disorders
    Kim Baker
    University of Maryland School of Medicine, Baltimore, MD, USA
    Adv Otorhinolaryngol 66:52-63. 2009
    ..Additionally, mice treated with atoh1 recover balance function. Currently vestibular diseases have few treatment options and several lines of evidence suggest that regeneration of hair cells may be ..
  67. ncbi Management of the patient with chronic dizziness
    A M Bronstein
    Neuro Otology Unit, Division of Neuroscience and Mental Health, Imperial College London, Charing Cross Hospital, London, UK
    Restor Neurol Neurosci 28:83-90. 2010
    ..In contrast, vestibular suppressants or tranquilisers should be reduced or, if possible, stopped...
  68. ncbi Direction and distance deficits in path integration after unilateral vestibular loss depend on task complexity
    Patrick Péruch
    Laboratoire de Neurophysiologie et Neuropsychologie, INSERM and Université de la Méditerranée, Faculte de Medecine de la Timone, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France
    Brain Res Cogn Brain Res 25:862-72. 2005
    ..On the whole, results suggest that the environment experienced by the patients is different after UVN and that a different internal spatial representation is constructed, especially for tasks requiring high levels of spatial processing...
  69. ncbi Improving the quality of life in patients with vestibular disorders: the role of medical treatments and physical rehabilitation
    E Mira
    Department of Otolaryngology and Head Neck Surgery, University of Pavia and IRCCS Policlinico San Matteo, Pavia, Italy
    Int J Clin Pract 62:109-14. 2008
    ..A profile of the compound betahistine and its efficacy on QoL indices in the treatment of Menière's disease and other forms of peripheral vertigo is also presented...
  70. ncbi Bilateral vestibulopathy: clinical, diagnostic, and genetic considerations
    Joanna C Jen
    David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Semin Neurol 29:528-33. 2009
    ..Furthermore, the study of bilateral vestibulopathy may shed light on the pathophysiology of more common vestibular syndromes such as benign recurrent vertigo and vestibular migraine...
  71. ncbi Screening for vestibular disorders: a study of clinicians' compliance with recommended practices
    Sharon H Polensek
    Rehabilitation Research and Development, Atlanta VA Medical Center, Atlanta, GA, USA
    Med Sci Monit 14:CR238-242. 2008
    ..The aim of this study was to examine clinical assessments used by providers in evaluating dizzy patients in outpatient clinics and the emergency department...
  72. pmc Effects of practicing tandem gait with and without vibrotactile biofeedback in subjects with unilateral vestibular loss
    Marco Dozza
    Department of Electronics, Computer Sciences and Systems, University of Bologna, Bologna, Italy
    J Vestib Res 17:195-204. 2007
    ....
  73. ncbi Control of sway using vibrotactile feedback of body tilt in patients with moderate and severe postural control deficits
    C Wall
    Department of Otology and Laryngology, Harvard Medical School, and Jenks Vestibular Diagnostic Laboratory Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    J Vestib Res 15:313-25. 2005
    ..This trend was found for both SOT 5 and 6, as well as the medium and large MCT. Additionally, during the MCT, the peak deflection and mean recovery time also decreased significantly...
  74. ncbi Outcomes after rehabilitation for adults with balance dysfunction
    Mary Beth Badke
    Department of Orthopedics and Rehabilitation, University of Wisconsin Hospital and Clinics, Madison, WI 53562, USA
    Arch Phys Med Rehabil 85:227-33. 2004
    ..To assess balance, dynamic gait, and dynamic visual acuity outcomes after a vestibular and balance rehabilitation program and to determine which variables were significantly associated with improved balance and ambulation...
  75. ncbi Auditory biofeedback substitutes for loss of sensory information in maintaining stance
    Marco Dozza
    Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Ave, Beaverton, OR 97006, USA
    Exp Brain Res 178:37-48. 2007
    ....
  76. ncbi Is hyperventilation-induced nystagmus more common in retrocochlear vestibular disease than in end-organ vestibular disease?
    Jeffrey Robichaud
    Department of Otolaryngology, The Toronto General Hospital University Health Network, Ontario
    J Otolaryngol 31:140-3. 2002
    ..This difference was very significant on chi-square testing (p < .002). Hyperventilation-induced nystagmus appears to be much more prevalent in retrocochlear pathology than in end-organ pathology...
  77. ncbi Epidemiology of vestibular vertigo: a neurotologic survey of the general population
    H K Neuhauser
    Department of Epidemiology, Robert Koch Institute, D 13353 Berlin, Germany
    Neurology 65:898-904. 2005
    ..The purpose of this study was to determine the prevalence and incidence of vestibular vertigo in the general population and to describe its clinical characteristics and associated factors...
  78. ncbi Vestibular paroxysmia: diagnostic features and medical treatment
    K Hufner
    Department of Neurology, Klinikum Grosshadern, Neurologisches Forschungshaus, Munich, Germany
    Neurology 71:1006-14. 2008
    ..Although VP was described more than 30 years ago by Jannetta and colleagues, we still need more reliable data on its diagnostic features and the efficacy of medical treatment...
  79. ncbi Vestibular rehabilitation and 6-month follow-up using objective and subjective measures
    A Meli
    ENT Rehabilitation Unit, San Raffaele Research Institute, Tosinvest Sanità s pa, Rome, Italy
    Acta Otolaryngol 126:259-66. 2006
    ..Vestibular rehabilitation improves both subjective and objective parameters, although no significant correlation between these two indices was found...
  80. ncbi Recovery of dynamic visual acuity in bilateral vestibular hypofunction
    Susan J Herdman
    Department of Rehabilitation Medicine, Emory University, Atlanta, GA 30322, USA
    Arch Otolaryngol Head Neck Surg 133:383-9. 2007
    ..To determine the effect of vestibular exercises on the recovery of visual acuity during head movement in patients with bilateral vestibular hypofunction (BVH)...
  81. ncbi Factor analysis and correlation between Dizziness Handicap Inventory and Dizziness Characteristics and Impact on Quality of Life scales
    N Perez
    Department of Otorhinolaryngology, University Hospital and Medical School, University of Navarra, Pamplona, Spain
    Acta Otolaryngol Suppl 545:145-54. 2001
    ..The DHI and UCLA-DQ questionnaires are multidimensional questionnaires for the assessment of the impact of dizziness and provide a model for vestibular disability and handicap...
  82. ncbi The activities-specific balance confidence scale and the dizziness handicap inventory: a comparison
    S L Whitney
    School of Health and Rehabilitation Sciences, University of Pittsburgh, PA 15260, USA
    J Vestib Res 9:253-9. 1999
    ..A moderately strong negative correlation was found between the scores of the two inventories (Ts = -0.6350). The results suggest that the ABC is a valid tool for use with individuals with complaints of dizziness...
  83. ncbi Tilt determination in MEMS inertial vestibular prosthesis
    Marc S Weinberg
    Draper Laboratory, Cambridge, MA 02139, USA
    J Biomech Eng 128:943-56. 2006
    ..Such a device would be used as a temporary aid during recovery from ablative inner-ear surgery, a postural monitor during rehabilitation (for example, hip surgery), and as a permanent prosthesis for those elderly prone to falls...
  84. ncbi Development of the vestibular disorders activities of daily living scale
    H S Cohen
    Bobby R Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Otolaryngol Head Neck Surg 126:881-7. 2000
    ..Existing scales of self-perceived disablement in patients with vestibular impairment either are too broad to detect the subtle deficits in this population or omit some important daily life tasks...
  85. ncbi Mental transformation abilities in patients with unilateral and bilateral vestibular loss
    Luzia Grabherr
    Department of Psychology, University of Bern, Muesmattstr 45, 3009 Bern, Switzerland
    Exp Brain Res 209:205-14. 2011
    ....
  86. ncbi Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs
    Carla Soler-Martín
    Departament de Ciències Fisiològiques II Universitat de Barcelona and Institut d Investigació Biomèdica de Bellvitge, 08907 Hospitalet de Llobregat, Spain
    Toxicol Sci 96:123-32. 2007
    ..This conclusion highlights the potential interest of this toxic effect and offers new animal models in which to decipher its basis...
  87. ncbi Vestibular dysfunction in migraine: effects of associated vertigo and motion sickness
    Seong Hae Jeong
    Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 300 Gumi dong, Bundang gu, Seongnam si, Gyeonggi do 463 707, South Korea
    J Neurol 257:905-12. 2010
    ..The increased tilt suppression may be an adaptive cerebellar mechanism to suppress the hyperactive vestibular system in migraineurs...
  88. ncbi Tai Chi and vestibular rehabilitation effects on gaze and whole-body stability
    Chris A McGibbon
    Institute of Biomedical Engineering, and Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada E3B 5A3
    J Vestib Res 14:467-78. 2004
    ..We conclude that GZS is most improved in those who receive VR, but that TC improves WBS and FFS without improving GZS, suggesting patients with VSP can rely on non-gaze related mechanisms to improve postural control...
  89. ncbi Is backward disequilibrium in the elderly caused by an abnormal perception of verticality? A pilot study
    Patrick Manckoundia
    INSERM ERIT M 0207 Motricité Plasticité, Universite de Bourgogne, Dijon, France
    Clin Neurophysiol 118:786-93. 2007
    ..We hypothesised that backward disequilibrium (BD), defined by a posterior position of the centre of mass with respect to the base of support, could be caused by a backward tilt in the perception of verticality...
  90. ncbi Ocular vestibular evoked myogenic potentials to bone conducted vibration of the midline forehead at Fz in healthy subjects
    S Iwasaki
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 119:2135-47. 2008
    ..To provide evidence that the response depends on otolithic function...
  91. ncbi Effects of vestibular rehabilitation on dizziness and imbalance
    F B Horak
    R S Dow Neurological Sciences Institute, Portland, OR 97209
    Otolaryngol Head Neck Surg 106:175-80. 1992
    ..This study takes the first step toward determining the efficacy of a specific exercise approach for reducing dizziness and imbalance in patients with chronic peripheral vestibular disorders...
  92. ncbi The n10 component of the ocular vestibular-evoked myogenic potential (oVEMP) is distinct from the R1 component of the blink reflex
    Y E Smulders
    Vestibular Research Laboratory, School of Psychology, University of Sydney, NSW, Australia
    Clin Neurophysiol 120:1567-76. 2009
    ..The early negative component of the oVEMP, n10, is due to vestibular stimulation, however it is similar to the early R1 component of the blink reflex. Here we seek to dissociate n10 from R1...
  93. ncbi Medical treatment of vestibular disorders
    Thomas Brandt
    Ludwig Maximilians University, Institute of Clinical Neuroscience, Marchioninistr 15, 81377 Munich, Germany
    Expert Opin Pharmacother 10:1537-48. 2009
    ..However, the majority of vestibular disorders have a benign cause, take a favorable natural course, and respond positively to therapy...
  94. ncbi Vestibulotoxicity as a consequence of systemically administered tobramycin in cystic fibrosis patients
    Renske J Scheenstra
    Department of Head and Neck Surgery, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands
    Acta Otolaryngol 129:4-7. 2009
    ..4%) in cystic fibrosis (CF) patients supports vestibulotoxicity screening in CF patients during or after tobramycin exposure. Prospective longitudinal investigation is required for a more specific evidence-based proposal...
  95. ncbi Inferior vestibular neuritis
    G M Halmagyi
    Neurology Department, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Sydney, Australia
    Ann N Y Acad Sci 956:306-13. 2002
    ....
  96. ncbi Dynamic locomotor function in normals and patients with vertigo
    K Ishikawa
    Department of Otorhinolaryngology, Akita University, School of Medicine, Hondo, Japan
    Acta Otolaryngol 121:241-4. 2001
    ..Those results could reflect a functional disorder of the gait control system caused by each disease. Significance of gait analysis is also discussed...
  97. ncbi Dynamic asymmetry of the vestibulo-ocular reflex in unilateral peripheral vestibular and cochleovestibular loss
    R Maire
    Clinic of Otolaryngology, Head and Neck Surgery, University Hospital Lausanne, Switzerland
    Laryngoscope 110:256-63. 2000
    ....
  98. ncbi Vestibular rehabilitation outcomes: velocity trajectory analysis of repeated bench stepping
    D Goldvasser
    Biomotion Laboratory, Massachusetts General Hospital, 40 Parkman Street, Boston, MA 02114, USA
    Clin Neurophysiol 111:1838-42. 2000
    ..To quantify vestibular rehabilitation (VR) outcomes in patients with vestibulospinal reflex pathology (VSP) using a new technique, high curvature analysis (HCA), that measures space trajectory stability...
  99. ncbi A case of normal ENG findings on air caloric stimulus that were not substantiated by water stimulus
    Kenneth H Brookler
    Neurotologic Associates, P C, New York City, USA
    Ear Nose Throat J 81:496-7. 2002
  100. ncbi Relationship between dynamic balance and self-reported handicap in patients who have unilateral peripheral vestibular loss
    Fabienne Mbongo
    Laboratoire de Neurobiologie des Reseaux Sensorimoteurs, CNRS UMR 7060 Université Paris 5, Paris 7, France
    Otol Neurotol 28:905-10. 2007
    ..The purpose of this study was to investigate whether Dizziness Handicap Inventory (DHI) score is related to postural performance as assessed by dynamic posturography...
  101. ncbi A comparison between oculomotor rehabilitation and vestibular electrical stimulation in unilateral peripheral vestibular deficit
    Stefania Barozzi
    Department of Otorhinolaryngology and Ophthalmology, University of Milan, Italy
    Int Tinnitus J 12:45-9. 2006
    ..Comparison of our two study groups did not show any significant difference, revealing that both forms of therapy are effective...

Research Grants62

  1. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2005
    ....
  2. CONDITIONAL GENE TARGETING IN HAIR CELLS
    Jian Zuo; Fiscal Year: 2003
    ..Ultimately, such studies will also contribute to the understanding, prevention, and treatment of vestibular diseases in humans. All mice made in FVB/N strain will be available to the academic community.
  3. VIRTUAL REALITY IN BALANCE DISORDERS
    Susan Whitney; Fiscal Year: 2007
    ..The data derived from the above three goals will help direct a randomized clinical trial that will assist in determining if virtual reality is an effective method of intervention with persons with vestibular dysfunction. ..
  4. MANAGEMENT OF ADAPTATION TO ALTERED SENSORIMOTOR STATES
    Helen Cohen; Fiscal Year: 2003
    ..abstract_text> ..
  5. TREATMENTS FOR BENIGN PAROXYSMAL POSITIONAL VERTIGO
    Helen Cohen; Fiscal Year: 2008
    ..4. Determine the influence of rhinosinusitis. A) Determine the prevalence of rhinosinusitis in patients with BPPV. B) Determine if the presence of rhinosinusitis affects severity of symptoms or response to treatment. ..
  6. RECOVERY OF VISUAL ACUITY IN VESTIBULAR DEFICITS
    SUSAN HERDMAN; Fiscal Year: 2002
    ..The rol of perceptual learning will be assessed by comparing the re- and post-exercise values of dynamic visual acuity measured in a target motion-head still paradigm. ..
  7. CERVICAL INFLUENCES ON BALANCE
    Joseph Furman; Fiscal Year: 2003
    ..To address specific aim #3, postural sway will be measured in response to naso-occipital optic flow within a virtual reality environment during several yaw head-on-trunk positions. ..
  8. VESTIBULO-OCULAR FUNCTION IN THE ELDERLY
    Joseph Furman; Fiscal Year: 2009
    ..Taken together, these studies will provide essential information regarding the influence of aging on several specific aspects of balance and thus may have practical implications regarding the management of age-related loss of balance. ..
  9. International Conference on Episodic Ataxia Syndromes
    Joanna Jen; Fiscal Year: 2005
    ..abstract_text> ..
  10. Genetics of Familial Episodic Ataxia
    Joanna C Jen; Fiscal Year: 2010
    ..Insights gained from the study will lead to improved diagnosis and treatment of familial episodic ataxia and the more common episodic vertigo syndromes. ..
  11. VOR adaptation/utility of saccades as rehab strategies
    Michael Schubert; Fiscal Year: 2008
    ..This is important for the long-term goals of this project, which are to determine the adaptive preferences that individuals with vestibular loss use to improve gaze stability. ..
  12. THE GENETIC & FUNCTIONAL ANATOMICAL BASIS OF HGPPS
    Joanna Jen; Fiscal Year: 2009
    ..Understanding the anatomical and molecular basis of HGPPS will provide insight into the genetically programmed neurodevelopment of the conjugate horizontal gaze center and other cranial nuclei in the brainstem. ..
  13. Pathobiology of Retinal Vasculopathy with Cerebal Leukodystrophy (RVCL)
    Joanna C Jen; Fiscal Year: 2010
    ..abstract_text> ..
  14. MUTATIONS IN CALCIUM CHANNELS CAUSING VERTIGO AND ATAXIA
    Joanna Jen; Fiscal Year: 2002
    ..The further relevance of this work to the more common basilar migraine and Meniere's syndrome is emphasized by the overlapping symptoms of vertigo and ataxia in the group of patients that we propose to study. ..
  15. VESTIBULAR INFLUENCES ON SPATIAL ORIENTATION
    Richard Lewis; Fiscal Year: 2008
    ..abstract_text> ..
  16. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2005
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  17. Development of semicircular canal prostheses for studies of vestibular plasticity
    DANIEL MERFELD; Fiscal Year: 2009
    ..abstract_text> ..
  18. Genetic Linkage & Candidate Gene Analysis in Two Pedigre
    VALERIE STREET; Fiscal Year: 2003
    ..Characterization of these normal and mutated gene products will contribute further to an understanding of the intricate workings of the auditory system. ..
  19. SENSORIMOTOR INTEGRATION IN HUMAN POSTURAL CONTROL
    Robert Peterka; Fiscal Year: 2009
    ..A better understanding of these active regulatory processes may lead to new rehabilitative methods and new clinical balance-function tests. ..
  20. Diseases of the Vestibular System
    Robert Baloh; Fiscal Year: 2006
    ..abstract_text> ..
  21. DIZZINESS IN OLDER PEOPLE
    Robert Baloh; Fiscal Year: 2006
    ..By continuing this longitudinal study of carefully studied older patients and controls, our multidisciplinary research team is in a good position to achieve our goals. ..
  22. EFFECTS OF DBS ON POSTURE AND OROMOTOR CONTROL
    Fay Horak; Fiscal Year: 2005
    ..Quantifying two types of postural and oromotor control in the same subjects will also substantially increase our understanding of the role of the basal ganglia in axial motor control. ..
  23. QUANTIFICATION OF CARTILAGE AND BONE DEFECTS USING MRI
    Chris Mc Gibbon; Fiscal Year: 2002
    ..Hypothesis: the analytical model can predict AC and SB thickness within 1 voxel dimension at a 95 percent confidence level and exhibit defect detection sensitivity and specificity greater than 98 percent. ..
  24. GENERATION OF MODELS FOR GENETIC HEARING LOSS
    DANA ORTEN; Fiscal Year: 2003
    ..Understanding disease processes will be the basis for designing and testing new treatments that could reduce or prevent human inherited hearing loss. ..
  25. PERIPHERAL AND CENTRAL POSTURAL DISORDERS IN THE ELDERLY
    Fay Horak; Fiscal Year: 2003
    ..abstract_text> ..
  26. The Influence of Head Position on Postural Vertical
    Diane Wrisley; Fiscal Year: 2003
    ..In experiment 2 we will determine whether the lateral bias of verticality will be observed during ambulation with various head positions. ..
  27. Genetics of Progressive Sensorineural Hearing Loss
    VALERIE STREET; Fiscal Year: 2008
    ..A molecular genetic and animal model approach as described in this grant proposal is one path to follow towards accomplishing this task. ..
  28. NEW METHOD TO IDENTIFY UNILATERAL VESTIBULAR DYSFUNCTION
    Robert Peterka; Fiscal Year: 2002
    ..Experimental results from subjects with different levels of partial unilateral vestibular loss will determine the effectiveness and reliability of the proposed new rotation test. ..
  29. VESTIBULAR SOMATOSENSORY INTERACTIONS FOR HUMAN POSTURE
    Fay Horak; Fiscal Year: 2002
    ....
  30. Adaptation of Spatial Orientation in Locomotion and Posture
    FAY BAHLING HORAK; Fiscal Year: 2010
    ..abstract_text> ..
  31. HEAD CONTROL MECHANISMS DURING VOLUNTARY TRUNK MOVEMENTS
    Timothy Hain; Fiscal Year: 2002
    ..The comparison of intact and BVL populations will elucidate why some persons with BVL recover relatively high functional levels, and others do not. ..
  32. EYE MOVEMENTS IN THE PERCEPTION OF DEPTH FROM MOTION
    Mark Nawrot; Fiscal Year: 2002
    ..The addition of an eye movement signal would expand the scope of the model to include motion parallax and its various interactions with binocular stereopsis. ..
  33. Complementary/Alternative Medicine for Vestibulopathy
    David Krebs; Fiscal Year: 2002
    ..The latter aim is purely exploratory and descriptive in nature. ..
  34. Sudden Hearing Loss Multicenter Treatment Trial
    Steven Rauch; Fiscal Year: 2008
    ..Thus the results of this study will have significant impact on evidence-based clinical practice guidelines for management of SSNHL. This application is for the collaborating Clinical Coordinating Center (CCC). ..
  35. Genetic Analysis of Age Related Hearing Impairment
    Rick A Friedman; Fiscal Year: 2010
    ..This improved knowledge base can be anticipated to constitute fertile ground for developing new evidence-based preventive and therapeutic approaches to treating ARHI. ..
  36. Refining the Genetic Basis of the Dopamine Hypothesis of Schizophrenia
    Michael Talkowski; Fiscal Year: 2008
    ..Our analyses may enable a better understanding of SZ pathogenesis, paving the way for development of rational therapeutics. [unreadable] [unreadable] [unreadable]..
  37. Micro-Electric Impedance Spectroscopy of Hair Cells
    Richard Rabbitt; Fiscal Year: 2009
    ..Dr. Rabbitt, Professor of Bioengineering at the University of Utah, will direct the BRP team. ..
  38. ID OF THE MOUSE DEAFNESS (DN) GENE ON CHROMOSOME 19
    Bronya Keats; Fiscal Year: 2002
    ..The deafness mouse is a model for nonsyndromic profound hearing impairment, and identifying the defective gene will be a valuable contribution to our understanding of the genes needed for normal cochlear function. ..
  39. TIME VARYING CHARACTERISTICS OF HUMAN POSTURAL SWAY
    Patrick Loughlin; Fiscal Year: 2002
    ..An objective of the research is to improve the evaluation and rehabilitation of individuals with balance disorders. ..
  40. Modeling Sensory Integration and Attention in Postural Control of Older Adults
    Patrick Loughlin; Fiscal Year: 2009
    ..Our research will provide new insights into the interaction of balance and attention through cortical brain imaging while subjects perform balance and attention tasks simultaneously. ..
  41. MEASUREMENT OF VESTIBULAR FUNCTION IN MENIERE'S DISEASE
    Steven Rauch; Fiscal Year: 2002
    ....
  42. Social Phobia: Assessment and Treatment of Social Skill
    Deborah Beidel; Fiscal Year: 2006
    ..The second study is designed to determine if skill deficits in generalized social phobics can be improved, and whether improvements in social skills are associated with improvements in overall social functioning. ..
  43. Regulation of auditory neuron neurite growth by activity
    Marlan Hansen; Fiscal Year: 2008
    ..The results of these studies will provide critical data on the consequences of electrical activity on SGN neurite growth and cochlear innervation. ..
  44. Borrelia lipoproteins with the cerebral microcirculation
    Diego Cadavid; Fiscal Year: 2007
    ..2. Investigate whether Vspl enters BMEC. 3. Determine whether Vspl crosses BMEC barriers. 4. Identify the structural features that mediate the interaction of Vspl with BMEC. [unreadable] [unreadable]..
  45. Genetic Architecture of Aging Skeletal Muscle
    Stephen Roth; Fiscal Year: 2005
    ..abstract_text> ..
  46. LIP READING AID VIA THE TONGUE
    Paul Bach Y Rita; Fiscal Year: 2004
    ..Successful completion of the lip reading system may lead to the development of a hearing substitution system for deaf persons. ..
  47. Study of a genetic network involved in ear development
    Rick Friedman; Fiscal Year: 2005
    ..These and future experiments represent the natural progression from my Mentored Clinical Scientist Development Award (K08). ..
  48. Genetic Aspects of Vestibular Dysfunction
    Stephen Roth; Fiscal Year: 2004
    ..The proposed project will generate important pilot data related to the genetics of vestibular dysfunction, thus fitting within the R21 grant mechanism. ..
  49. WEARABLE ARTIFICIAL LABYRINTH IN MOTION SICKNESS/VERTIGO
    WESLEY KRUEGER; Fiscal Year: 2005
    ....
  50. Mechanism of Opiate Induced Audiovestibular Dysfunction
    Gail Ishiyama; Fiscal Year: 2006
    ....
  51. Speech Production in Children with Cochlear Implants
    Sneha Bharadwaj; Fiscal Year: 2006
    ..abstract_text> ..
  52. Walking Activity and the Burden of Multiple Morbidities
    James Cavanaugh; Fiscal Year: 2006
    ..Study findings are likely to be relevant to aging studies arising from a variety of basic and clinical science disciplines. ..
  53. Behavior Treatment for Chronic PTSD
    Deborah Beidel; Fiscal Year: 2007
    ..g., depression); and (4) treatment credibility and satisfaction. This application is submitted under the R21 (Exploratory/Developmental Grants) Mechanism. ..
  54. Optotrack Motion Analysis System
    Timothy Hain; Fiscal Year: 2005
    ..Motion analysis equipment is critical to all of our research faculty, and we have also recently added investigators to the department who need motion analysis capabilities. ..
  55. 11th International conference on cochlear implants in children
    Craig Buchman; Fiscal Year: 2007
    ..The purpose of this symposium is to continue this necessary and productive interaction. [unreadable] [unreadable] [unreadable]..
  56. Building a New Model for Diagnosis of ED Dizzy Patients
    David Newman Toker; Fiscal Year: 2007
    ..This research project and the research paradigms derived from it will form the nucleus of a career devoted to research in medical decision-making, causes of diagnostic errors, and methods to preventthem. ..
  57. VIRTUAL REALITY FOR BALANCE REHABILITATION
    Mark Redfern; Fiscal Year: 2003
    ....
  58. MOLECULAR BASIS OF VESTIBULAR EFFERENT FUNCTION
    P Ashley Wackym; Fiscal Year: 2008
    ..abstract_text> ..
  59. Aerobic Exercise Intervention for Knee Osteoarthritis
    Kenton Kaufman; Fiscal Year: 2005
    ..Hypothesis: A effective exercise prescription for adults with degenerative joint disease is dependent on knee compartment involvement, CIA stage, BMI, and type of exercise prescribed. ..
  60. Genetic Epidemiology of Aging Skeletal Muscle
    Stephen Roth; Fiscal Year: 2007
    ..abstract_text> ..
  61. Aging and vestibular disease on postural control
    PATRICK SPARTO; Fiscal Year: 2005
    ..abstract_text> ..