hyperacusis

Summary

Summary: An abnormally disproportionate increase in the sensation of loudness in response to auditory stimuli of normal volume. COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; FACIAL NERVE DISEASES; STAPES SURGERY; and other disorders may be associated with this condition.

Top Publications

  1. ncbi Tinnitus retraining therapy: a different view on tinnitus
    Pawel J Jastreboff
    Tinnitus and Hyperacusis Center, Department of Otolaryngology Head and Neck Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
    ORL J Otorhinolaryngol Relat Spec 68:23-9; discussion 29-30. 2006
  2. ncbi When tinnitus loudness and annoyance are discrepant: audiological characteristics and psychological profile
    Wolfgang Hiller
    Department of Clinical Psychology, University of Mainz, Mainz, Germany
    Audiol Neurootol 12:391-400. 2007
  3. ncbi Psychometric normalization of a hyperacusis questionnaire
    S Khalfa
    Neurosciences and Sensory Systems, Lyon, France
    ORL J Otorhinolaryngol Relat Spec 64:436-42. 2002
  4. ncbi [Loudness discomfort level in normal hearing individuals]
    Keila Alessandra Baraldi Knobel
    Faculdade de Medicina da Universidade de Sao Paulo
    Pro Fono 18:31-40. 2006
  5. ncbi Hyperacusis and misophonia: the lesser-known siblings of tinnitus
    Paula Schwartz
    Tinnitus and Hyperacusis Clinic, Twin Cities, USA
    Minn Med 94:42-3. 2011
  6. ncbi Assessment and amelioration of hyperacusis in tinnitus patients
    René Dauman
    Tinnitus Clinic, Department of Otolaryngology Head and Neck Surgery, Unit of Audiology, University Hospital of Bordeaux, University Victor Segalen Bordeaux 2, Bordeaux, France
    Acta Otolaryngol 125:503-9. 2005
  7. ncbi Self-reported hearing problems among older adults: prevalence and comparison to measured hearing impairment
    Samuli Hannula
    Department of Clinical Medicine, Otorhinolaryngology, University of Oulu, Oulu, Finland
    J Am Acad Audiol 22:550-9. 2011
  8. pmc Behavioral evidence for possible simultaneous induction of hyperacusis and tinnitus following intense sound exposure
    G Chen
    Department of Neurosciences, Lerner Research Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Assoc Res Otolaryngol 14:413-24. 2013
  9. ncbi Gap detection methods for assessing salicylate-induced tinnitus and hyperacusis in rats
    Jeremy G Turner
    Department of Surgery Otolaryngology Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794 9629, USA
    Am J Audiol 17:S185-92. 2008
  10. ncbi Hyperacusis: review and clinical guidelines
    U Katzenell
    Department of Otolaryngology, Wolfson Medical Center, Holon, Israel
    Otol Neurotol 22:321-6; discussion 326-7. 2001

Detail Information

Publications220 found, 100 shown here

  1. ncbi Tinnitus retraining therapy: a different view on tinnitus
    Pawel J Jastreboff
    Tinnitus and Hyperacusis Center, Department of Otolaryngology Head and Neck Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
    ORL J Otorhinolaryngol Relat Spec 68:23-9; discussion 29-30. 2006
    ..It is crucial to assess and treat tinnitus, decreased sound tolerance, and hearing loss simultaneously. Results from various groups have shown that TRT can be an effective method of treatment...
  2. ncbi When tinnitus loudness and annoyance are discrepant: audiological characteristics and psychological profile
    Wolfgang Hiller
    Department of Clinical Psychology, University of Mainz, Mainz, Germany
    Audiol Neurootol 12:391-400. 2007
    ..71), vertigo/dizziness (OR = 1.94) or hyperacusis (OR = 4.96). Another significant predictor was history of neurological disease (OR = 3.16)...
  3. ncbi Psychometric normalization of a hyperacusis questionnaire
    S Khalfa
    Neurosciences and Sensory Systems, Lyon, France
    ORL J Otorhinolaryngol Relat Spec 64:436-42. 2002
    Clinical hyperacusis consists of a marked intolerance to ordinary environmental sounds, while hearing thresholds are quite often normal...
  4. ncbi [Loudness discomfort level in normal hearing individuals]
    Keila Alessandra Baraldi Knobel
    Faculdade de Medicina da Universidade de Sao Paulo
    Pro Fono 18:31-40. 2006
    Loudness Discomfort Level (LDL), a test used in the hearing aid fitting process, has also been recommended to evaluate patients with tinnitus and/or suspect of hyperacusis.
  5. ncbi Hyperacusis and misophonia: the lesser-known siblings of tinnitus
    Paula Schwartz
    Tinnitus and Hyperacusis Clinic, Twin Cities, USA
    Minn Med 94:42-3. 2011
    b>Hyperacusis (decreased sound tolerance) and misophonia (fear of sound) are two conditions about which little is known. Consequently, physicians often struggle when they encounter patients who are affected by them...
  6. ncbi Assessment and amelioration of hyperacusis in tinnitus patients
    René Dauman
    Tinnitus Clinic, Department of Otolaryngology Head and Neck Surgery, Unit of Audiology, University Hospital of Bordeaux, University Victor Segalen Bordeaux 2, Bordeaux, France
    Acta Otolaryngol 125:503-9. 2005
    Tinnitus can be bothersome even without hyperacusis. The good correlation found in this study between the multiple-activity scale for hyperacusis (MASH) score and the overall annoyance of hyperacusis score supports the reliability of ..
  7. ncbi Self-reported hearing problems among older adults: prevalence and comparison to measured hearing impairment
    Samuli Hannula
    Department of Clinical Medicine, Otorhinolaryngology, University of Oulu, Oulu, Finland
    J Am Acad Audiol 22:550-9. 2011
    ..between self-reported hearing difficulties and measured hearing thresholds is unclear and, according to our knowledge, there are no previous population-based studies reporting hearing thresholds among subjects with hyperacusis.
  8. pmc Behavioral evidence for possible simultaneous induction of hyperacusis and tinnitus following intense sound exposure
    G Chen
    Department of Neurosciences, Lerner Research Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Assoc Res Otolaryngol 14:413-24. 2013
    Many human subjects suffering from chronic tinnitus also suffer from hyperacusis, a heightened perception of loudness at moderate to intense sound levels...
  9. ncbi Gap detection methods for assessing salicylate-induced tinnitus and hyperacusis in rats
    Jeremy G Turner
    Department of Surgery Otolaryngology Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794 9629, USA
    Am J Audiol 17:S185-92. 2008
    ..These options are briefly reviewed, followed by data suggesting that gap detection procedures might be used to efficiently measure acute, salicylate-induced tinnitus and possibly hyperacusis in rats.
  10. ncbi Hyperacusis: review and clinical guidelines
    U Katzenell
    Department of Otolaryngology, Wolfson Medical Center, Holon, Israel
    Otol Neurotol 22:321-6; discussion 326-7. 2001
    To review the current known causes of hyperacusis and the different hypotheses concerning its etiology, and to suggest clinical guidelines.
  11. pmc Structural neuroanatomy of tinnitus and hyperacusis in semantic dementia
    Colin J Mahoney
    Dementia Research Centre, Institute of Neurology, University College London, London, UK
    J Neurol Neurosurg Psychiatry 82:1274-8. 2011
    Tinnitus and hyperacusis are common symptoms of excessive auditory perception in the general population; however, their anatomical substrates and disease associations continue to be defined.
  12. ncbi Hearing loss, hyperacusis, or tinnitus: what is modeled in animal research?
    Jos J Eggermont
    Department of Physiology and Pharmacology, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada T2N 1N4
    Hear Res 295:140-9. 2013
    ..Furthermore, the synaptic mechanisms underlying spontaneous firing rate changes may be different from those involved in driven neural activity...
  13. pmc Hyperacusis
    David M Baguley
    Audiology 94, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    J R Soc Med 96:582-5. 2003
  14. ncbi The relationship of tinnitus, hyperacusis, and hearing loss
    Jeffrey J Nelson
    Division of Dentistry Otolaryngology, Department of Surgery, Medical College of Ohio, Toledo 43614 5807, USA
    Ear Nose Throat J 83:472-6. 2004
    The triad of tinnitus, hyperacusis, and hearing loss remains an often-underdiagnosed combination of symptoms that causes physical, mental, and emotional distress for millions of patients...
  15. pmc Age-related hearing loss in C57BL/6J mice has both frequency-specific and non-frequency-specific components that produce a hyperacusis-like exaggeration of the acoustic startle reflex
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Meliora Hall, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 8:539-50. 2007
    ..This hyperacusis-like effect appeared in all mice but was especially pronounced in mice with more serious hearing loss...
  16. pmc An active loudness model suggesting tinnitus as increased central noise and hyperacusis as increased nonlinear gain
    Fan Gang Zeng
    Department of Anatomy and Neurobiology, University of California, Irvine, CA 92697 5320, USA
    Hear Res 295:172-9. 2013
    The present study uses a systems engineering approach to delineate the relationship between tinnitus and hyperacusis as a result of either hearing loss in the ear or an imbalanced state in the brain...
  17. ncbi Correlation between hyperacusis measurements in daily ENT practice
    Olivier M Meeus
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital UZA, University of Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Int J Audiol 49:7-13. 2010
    The aim of this study was to investigate hyperacusis measurement tools and to assess the correlation between diagnostic methods for hyperacusis in daily ENT practice...
  18. pmc Noise-induced tinnitus using individualized gap detection analysis and its relationship with hyperacusis, anxiety, and spatial cognition
    Edward Pace
    Department of Otolaryngology Head and Neck Surgery, Wayne State University School of Medicine, Detroit, Michigan, United States of America
    PLoS ONE 8:e75011. 2013
    Tinnitus has a complex etiology that involves auditory and non-auditory factors and may be accompanied by hyperacusis, anxiety and cognitive changes...
  19. ncbi Celebrating a decade of evaluation and treatment: the University of Maryland Tinnitus & Hyperacusis Center
    S L Gold
    University of Maryland Tinnitus and Hyperacusis Center, Baltimore, USA
    Am J Audiol 9:69-74. 2000
    The University of Maryland Tinnitus & Hyperacusis Center in Baltimore was the first center in the United States dedicated to the evaluation and treatment of tinnitus and hyperacusis patients implementing an habituation-based protocol ..
  20. ncbi Sleep complaints in elderly tinnitus patients: a controlled study
    Sylvie Hébert
    Ecole d Orthophonie et d Audiologie, Centre de recherche en neuropsychologie et en cognition, Universite de Montreal, Canada
    Ear Hear 28:649-55. 2007
    ..Sleep difficulties are among the most frequent complaints associated with tinnitus. Yet most studies reporting on this problem are rather succinct, and all of them lack proper age- and health-matched control subjects...
  21. ncbi Advances in the neurobiology of hearing disorders: recent developments regarding the basis of tinnitus and hyperacusis
    Marlies Knipper
    University of Tubingen, Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre THRC, Molecular Physiology of Hearing, Tubingen, Germany Electronic address
    Prog Neurobiol 111:17-33. 2013
    ..Afferent neuronal degeneration has been suggested to be involved in hyperacusis (over sensitivity to sound) and tinnitus (a phantom sound percept)...
  22. ncbi Self-reported and behavioral sound avoidance in tinnitus and hyperacusis subjects, and association with anxiety ratings
    Lena Blaesing
    Department of Clinical Psychology and Psychotherapy, Georg August University of Gottingen, Germany
    Int J Audiol 51:611-7. 2012
    The purpose of the study was to analyse the role of sound avoidance and anxiety in tinnitus subjects with hyperacusis, defined as hypersensitivity to low to moderate intensity sounds.
  23. ncbi Noise exposure enhances auditory cortex responses related to hyperacusis behavior
    Wei Sun
    Center for Hearing and Deafness, The State University of New York at Buffalo, NY 14214, USA
    Brain Res 1485:108-16. 2012
    b>Hyperacusis, a marked intolerance to normal environmental sound, is a common symptom in patients with tinnitus, Williams syndrome, autism, and other neurologic diseases...
  24. ncbi Psychiatric comorbidity and personality traits in patients with hyperacusis
    Linda Jüris
    Department of Neuroscience, Uppsala University, Uppsala University Hospital, Uppsala, Sweden
    Int J Audiol 52:230-5. 2013
    b>Hyperacusis, defined as unusual intolerance of ordinary environmental sounds, is a common problem. In spite of this, there is limited understanding of the underlying mechanisms...
  25. ncbi Hyperacusis, sound annoyance, and loudness hypersensitivity in children
    Claudia Barros Coelho
    Department of Otolaryngology of the University of São Paulo Medical School, Sao Paulo, Brazil
    Prog Brain Res 166:169-78. 2007
    The objective of the present study was to estimate the prevalence of hyperacusis among school-aged children. We define hyperacusis as lowered loudness discomfort levels (LDL) associated with an abnormal annoyance to sounds...
  26. ncbi The relationship between migraine pain and other associated symptoms
    L Kelman
    Headache Center of Atlanta, Atlanta, GA 30342, USA
    Cephalalgia 26:548-53. 2006
    ..Taste abnormality and osmophobia are better correlated with headache duration rather than headache intensity...
  27. ncbi Central hyperacusis with phonophobia in multiple sclerosis
    H Weber
    Department of Neurology and Clinical Neurophysiology, Klinikum Augsburg, Augsburg, Germany
    Mult Scler 8:505-9. 2002
    Hearing disorders are a well-described symptom in patients with multiple sclerosis (MS). Unilateral or bilateral hyperacusis or deafness in patients with normal sound audiometry is often attributed to demyelinating lesions in the central ..
  28. ncbi Aversion, awareness, and attraction: investigating claims of hyperacusis in the Williams syndrome phenotype
    Daniel J Levitin
    Department of Psychology, McGill University, Canada
    J Child Psychol Psychiatry 46:514-23. 2005
    ..Previously published reports indicate that people with WS experience hyperacusis, yet careful examination reveals that the term 'hyperacusis' has been used indiscriminately in the literature ..
  29. ncbi Hyperacusis in Williams syndrome: characteristics and associated neuroaudiologic abnormalities
    D Gothelf
    Behavioral Neurogenetics Center, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    Neurology 66:390-5. 2006
    b>Hyperacusis and phonophobia are common, debilitating symptoms in Williams syndrome (WS), yet little is known about their underlying audiologic and neurologic processes.
  30. ncbi Hyperacusis in Williams syndrome
    L B Johnson
    Department of Otolaryngology, Dalhousie University, Halifax, Nova Scotia
    J Otolaryngol 30:90-2. 2001
    OBJECTIVE: To define hyperacusis in audiologic parameters and to further elucidate central and peripheral auditory pathways. DESIGN AND SETTING: Theories surrounding hyperacusis have always been highly debated...
  31. ncbi Brain activation in patients with idiopathic hyperacusis
    Juen Haur Hwang
    Department of Otolaryngology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, School of Medicine, Tzu Chi University, Hualien, Taiwan
    Am J Otolaryngol 30:432-4. 2009
    The neural network associated with idiopathic hyperacusis is still not well known...
  32. ncbi Fears, hyperacusis and musicality in Williams syndrome
    Stefan Blomberg
    Department of Behavioural Sciences, Linkoping University, Sweden
    Res Dev Disabil 27:668-80. 2006
    The study investigated the prevalence of fear and hyperacusis and the possible connections between fear, hyperacusis and musicality in a Swedish sample of individuals with Williams syndrome (WS)...
  33. ncbi Pain threshold improvement for chronic hyperacusis patients in a prospective clinical study
    Michael Zazzio
    Audio Laser Kliniken, Flygeln, Hovmantorp, Sweden
    Photomed Laser Surg 28:371-7. 2010
    ..therapy in combination with pulsed electromagnetic field therapy/repetitive transcranial magnetic stimulation (rTMS) and the control of reactive oxygen species (ROS) would lead to positive treatment results for hyperacusis patients.
  34. ncbi Hypersensitivity to sound (hyperacusis): a prevalence study conducted via the Internet and post
    Gerhard Andersson
    Department of Psychology, Uppsala University, Uppsala, Sweden
    Int J Audiol 41:545-54. 2002
    The present study explored the prevalence and descriptive characteristics of hyperacusis, defined as unusual intolerance of ordinary environmental sounds...
  35. ncbi Dysfunction of the auditory efferent system in patients with traumatic brain injuries with tinnitus and hyperacusis
    J Attias
    Department of Communication Disorders, Haifa University, Petach Tikva, Israel
    J Basic Clin Physiol Pharmacol 16:117-26. 2005
    Tinnitus, hyperacusis and difficulty listening in background noise are common symptoms reported by patients with traumatic brain injury (TBI)...
  36. ncbi Severity of hyperacusis predicts individual differences in speech perception in Williams Syndrome
    M Elsabbagh
    Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK
    J Intellect Disabil Res 55:563-71. 2011
    ..Individuals with WS display an unusual sensitivity to noise, known as hyperacusis.
  37. ncbi A cognitive model of tinnitus and hyperacusis; a clinical tool for patient information, appeasement and assessment
    Olav Wagenaar
    Erasmus Medical Center, Department of Otorhinolaryngology, Rotterdam, The Netherlands
    Int Tinnitus J 16:66-72. 2010
    Tinnitus and hyperacusis are both aggravating audiological symptoms. Their underlying mechanisms are not fully understood, but the pathophysiology involves a central mechanism rather than a peripheral one. There is no curative treatment...
  38. pmc Hyperacusis in patients with complex regional pain syndrome related dystonia
    M J M de Klaver
    Department of Neurology, Leiden University Medical Centre, PO Box 9600, Leiden, The Netherlands
    J Neurol Neurosurg Psychiatry 78:1310-3. 2007
    ..We noted that more severely affected patients may experience hyperacusis, which may also reflect central involvement...
  39. ncbi [Hyperacusis, phonophobia, and recruitment. Abnormal deviations of hearing associated with hypersensitivity to sound]
    H Schaaf
    Tinnitus Klinik Arolsen
    HNO 51:1005-11. 2003
    ..One can distinguish between recruitment accompanying inner ear hearing loss, hyperacusis with a general hypersensitivity to sound of any frequency, and phonophobia as an anxious sensitivity towards ..
  40. ncbi Semicircular canal function before and after surgery for superior canal dehiscence
    John P Carey
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Otol Neurotol 28:356-64. 2007
    ..To characterize semicircular canal function before and after surgery for superior semicircular canal dehiscence (SCD) syndrome...
  41. ncbi Acoustic shock
    D J McFerran
    Department of Otolaryngology and Head and Neck Surgery, Essex County Hospital, Colchester, UK
    J Laryngol Otol 121:301-5. 2007
    ..has not yet been proposed, but the potential utility of modern therapeutic techniques for tinnitus and hyperacusis are considered...
  42. ncbi [DPOAE in tinnitus patients with cochlear hearing loss considering hyperacusis and misophonia]
    Aleksandra Sztuka
    Katedra i Klinika Otolaryngologii AM we Wrocławiu
    Otolaryngol Pol 60:765-72. 2006
    ..DPOAE parameters most useful in localizing tinnitus generators and estimation of hypothetic influence of hyperacusis and misophony on parameters of DPOAE in tinnitus patients with cochlear hearing loss...
  43. ncbi [Rock music and hearing disorders]
    Carl Christian Lein Størmer
    Institutt for klinisk medisin, Det medisinske fakultet, Universitetet i Tromsø, 9037 Tromsø
    Tidsskr Nor Laegeforen 127:874-7. 2007
    ..The aim of this paper was to get an overview of hearing loss, tinnitus and hyperacusis among rock musicians.
  44. ncbi Tensor tympani muscle: strange chewing muscle
    Luis Miguel Ramirez
    Universidad Javeriana, Santa Fe de Bogota, Colombia
    Med Oral Patol Oral Cir Bucal 12:E96-100. 2007
    ..Common symptomatology is frequently observed in otic symptoms and temporomandibular disorders during daily practice; this should be understood by each discipline from a broad, anatomical and clinical perspective...
  45. pmc Factors associated with migraine-related quality of life and disability in adolescents: a preliminary investigation
    Gregg A Tkachuk
    Department of Psychology, Ohio University, Athens, OH, USA
    Headache 43:950-5. 2003
    ..Subjects.-The 37 participants were 51.4% female, and averaged 14.3 years of age and 4.1 migraines per month for the previous 36 months...
  46. ncbi Clinical guide for audiologic tinnitus management II: Treatment
    James A Henry
    VA Medical Center, Portland, OR 97207, USA
    Am J Audiol 14:49-70. 2005
    ..2 that address the need for basic procedures that can be used commonly by audiologists to manage patients with clinically significant tinnitus, as well as hyperacusis. The method described is termed audiologic tinnitus management (ATM).
  47. ncbi Effect of slow-acting wide dynamic range compression on measures of intelligibility and ratings of speech quality in simulated-loss listeners
    Peninah S Rosengard
    Harvard MIT Division of Health Sciences and Technology and Massachusetts Institute of Technology, USA
    J Speech Lang Hear Res 48:702-14. 2005
    ....
  48. ncbi A revised model of loudness perception applied to cochlear hearing loss
    Brian C J Moore
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Hear Res 188:70-88. 2004
    ..Like the earlier model, the new model can account for the loudness recruitment and reduced loudness summation that are typically associated with cochlear hearing loss...
  49. ncbi Drop attacks secondary to superior canal dehiscence syndrome
    Krister Brantberg
    Department of Audiology, Karolinska University Hospital, Stockholm, Sweden
    Neurology 64:2126-8. 2005
    ..Neither had sound- or pressure-induced nystagmus. Repair of the dehiscence in one case stopped the drop attacks, supporting a causal relationship between the dehiscence and the drop attacks...
  50. ncbi Relation of hyperacusis in sensorineural tinnitus patients with normal audiological assessment
    Sandra Lira Bastos de Magalhães
    Department of Otorhinolaryngology, Pontific Catholic University Sorocaba, Sao Paulo, Brazil
    Int Tinnitus J 9:79-83. 2003
    b>Hyperacusis is mainly a consequence of the noise level in the twenty-first century, owing to dramatic changes in people's lifestyles. Of every 100 people with otological complaints (e.g...
  51. ncbi Perception of clear fricatives by normal-hearing and simulated hearing-impaired listeners
    Kazumi Maniwa
    Department of Linguistics, The University of Kansas, Lawrence, Kansas 66044, USA
    J Acoust Soc Am 123:1114-25. 2008
    ..Correlations between acoustic and perceptual data were less consistent for listeners with simulated impairment, and suggested that lower-frequency information may play a role...
  52. ncbi Use of cluster analysis to validate IHS diagnostic criteria for migraine and tension-type headache
    S Bruehl
    Center for Pain Studies, Rehabilitation Institute of Chicago, Ill 60611, USA
    Headache 39:181-9. 1999
    ..Overall, these data support migraine and tension-type headache as distinct entities, and provide support for the IHS diagnostic criteria with minor modifications...
  53. ncbi Tinnitus: pharmacological topodiagnosis
    Dario Alpini
    Ear, Nose, and Throat Otoneurology Service Scientific Institute, Don Gnocchi Foundation, Milan, Italy
    Int Tinnitus J 10:91-3. 2004
    ..consists of specific audiological tests evaluating the characteristics of symptoms (annoyance, pitch, loudness, hyperacusis) and of several pharmacological tests carried out through the administration of particular drugs, the ..
  54. ncbi Estimates of loudness, loudness discomfort, and the auditory dynamic range: normative estimates, comparison of procedures, and test-retest reliability
    LaGuinn P Sherlock
    University of Maryland, Baltimore, MD 21201, USA
    J Am Acad Audiol 16:85-100. 2005
    ....
  55. ncbi Tinnitus in children and associated risk factors
    Claudia Barros Coelho
    Department of Otolaryngology of the University of São Paulo Medical School, Sao Paulo, Brazil
    Prog Brain Res 166:179-91. 2007
    ..Related factors were age, hearing loss, and history of noise exposure, motion sickness and hyperacusis. Estimates of the prevalence of tinnitus clearly depend on how tinnitus is defined...
  56. ncbi Questionnaire investigation of musicians' use of hearing protectors, self reported hearing disorders, and their experience of their working environment
    Heli Laitinen
    Heikki Helimäki Ltd, Helsinki, Finland
    Int J Audiol 47:160-8. 2008
    ..Furthermore, musicians can suffer from tinnitus, hyperacusis, and distortion, among other hearing disorders, which can affect their work more severely than a hearing loss...
  57. ncbi Tolerable hearing aid delays. V. Estimation of limits for open canal fittings
    Michael A Stone
    Department of Experimental Psychology, University of Cambridge, Cambridge, England
    Ear Hear 29:601-17. 2008
    ....
  58. ncbi Testing the concept of softness imperception: loudness near threshold for hearing-impaired ears
    Brian C J Moore
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
    J Acoust Soc Am 115:3103-11. 2004
    ..g., 2 dB SL matched 2 dB SL). This relationship held for SLs up to 4-10 dB, depending on the subject. These results are not consistent with the concept of softness imperception...
  59. ncbi The effects of neural synchronization and peripheral compression on the acoustic-reflex threshold
    Matthias Müller-Wehlau
    Medizinische Physik, Universitat Oldenburg, D 26111 Oldenburg, Germany
    J Acoust Soc Am 117:3016-27. 2005
    ..These differences might be useful for objective recruitment detection in clinical diagnostics...
  60. ncbi Adaptive plasticity of loudness induced by chronic attenuation and enhancement of the acoustic background
    C Formby
    J Acoust Soc Am 114:55-8. 2003
  61. ncbi Tinnitus retraining therapy for patients with tinnitus and decreased sound tolerance
    Pawel J Jastreboff
    Tinnitus and Hyperacusis Center, Department of Otolaryngology, Emory University School of Medicine, 1365A Clifton Road, NE, Atlanta, GA 30322, USA
    Otolaryngol Clin North Am 36:321-36. 2003
    ..3) TRT does not require frequent clinic visits and has no side effects; however, (4) Special training of health providers involved in this treatment is required for this treatment to be effective...
  62. ncbi [The assessment of subjective distress related to hyperacusis with a self-rating questionnaire on hypersensitivity to sound]
    M Nelting
    Tinnitus Klinik Arolsen, Bad Arolsen, Germany
    Laryngorhinootologie 81:327-34. 2002
    ..So far there has been no adequate measure to assess or illustrate, in terms of different levels, subjective distress related to hypersensitivity to sound...
  63. ncbi [Central hyperacusis with phonophobia in multiple sclerosis]
    K Pfadenhauer
    Klinikum Augsburg, Neurologische Klinik mit Klinischer Neurophysiologie, Stenglinstrasse 2, 86156 Augsburg
    Nervenarzt 72:928-31. 2001
    ..modulation which controls the regulation of sensitivity of incoming acoustic stimuli seems to be the cause of hyperacusis. All our patients developed clinically confirmed MS in the further course after suffering from phonophobia as ..
  64. ncbi [Otoacoustic emissions and recruitment]
    Wiesław Konopka
    Zakład Diagnostyki Audiologicznej i Elektrofizjologicznej Katedry Chirurgii Głowy i Szyi Uniwersytetu Medycznego
    Otolaryngol Pol 59:731-6. 2005
    ..There have been many explanation connected this phenomena so far. It has been suggested that otoacoustic emissions might be more sensitive in assessment of changes to the cochlea caused by noise than pure tone audiometry...
  65. ncbi Acoustic injury and TRPV1 expression in the cochlear spiral ganglion
    Carol A Bauer
    Southern Illinois University School of Medicine, Division of Otolaryngology Head and Neck Surgery, Springfield, IL 62794, USA
    Int Tinnitus J 13:21-8. 2007
    ..These results suggest that TRPV1 may participate after cochlear injury in a signal cascade that is responsible for the neuroplastic events leading to tinnitus and hyperacusis.
  66. pmc Current perspectives on tinnitus
    D M Baguley
    Audiology, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Arch Dis Child 86:141-3. 2002
  67. ncbi Long-term assessment of auditory changes resulting from a single noise exposure associated with non-occupational activities
    Nicolas Schmuzigert
    Department of Otorhinolaryngology, University Hospital, Basel, Switzerland
    Int J Audiol 45:46-54. 2006
    ..Furthermore, the majority of the subjects from both groups reported tinnitus and hypersensitivity to sound at follow-up, but with minimal impact on their lives...
  68. ncbi Tinnitus and Ménière's disease: characteristics and prognosis in a tinnitus clinic sample
    C Herraiz
    Unidad de Otorrinolaringologia, Fundacion Hospital Alcorcon, Madrid, C Budapest, 1 Alcorcón, 28922, Madrid, Spain
    Eur Arch Otorhinolaryngol 263:504-9. 2006
    ..01). We found a statistical association (P<0.05) between tinnitus intensity and worse hearing loss or hyperacusis, but it was not influenced by number of vertigo spells...
  69. ncbi The prevalence and onset of gaze modulation of tinnitus and increased sensitivity to noise after translabyrinthine vestibular schwannoma excision
    David M Baguley
    Department of Audiology, Addenbrooke s Hospital, Cambridge, United Kingdom
    Otol Neurotol 27:220-4. 2006
    ..To determine the prevalence and timing of onset of gaze-modulated tinnitus and increased sensitivity to noise in patients who had undergone translabyrinthine excision of a vestibular schwannoma...
  70. ncbi Identification of negative predictors of pain-free response to triptans: analysis of the eletriptan database
    H C Diener
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 28:35-40. 2008
    ..placebo (all P < 0.01). Thus, eletriptan and sumatriptan are efficacious in difficult-to-treat patients at high risk for non-response to triptans...
  71. ncbi Specific findings in distortion product otoacoustic emissions and growth functions with chronic tinnitus
    Gerhard Hesse
    Tinnitus Klinik Arolsen, Bad Arolsen, Germany
    Int Tinnitus J 11:6-13. 2005
    ..Regarding therapeutic approaches, these central functions can be trained by hearing therapy, as we know from patients' rehabilitation...
  72. ncbi A meta-analysis of the placebo response in acute migraine and how this response may be influenced by some of the characteristics of clinical trials
    Ana Macedo
    Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Eur J Clin Pharmacol 62:161-72. 2006
    ..These data reinforce the need for knowing the magnitude of the placebo response in each specific situation during the planning of clinical trials on acute migraine...
  73. ncbi Speech perception, localization, and lateralization with bilateral cochlear implants
    Richard J M van Hoesel
    CRC for Cochlear Implant and Hearing Aid Innovation, Melbourne, Victoria, Australia
    J Acoust Soc Am 113:1617-30. 2003
    ..The data do indicate, however, that effects of interaural timing cues are weaker than those from interaural level cues and according to our psychophysical findings rely on the availability of low-rate information below a few hundred Hz...
  74. ncbi Enriched acoustic environment rescales auditory sensitivity
    Arnaud Jean Noreña
    Laboratory of Integrative and Adaptative Neurobiology, University of Provence St Charles, Pole 3C, Marseille, France
    Neuroreport 18:1251-5. 2007
    ..a decrease in sensory inputs could increase this central gain and cause an auditory hypersensitivity or hyperacusis. According to this model, individuals with hyperacusis, provided with an enriched acoustic environment ..
  75. ncbi [Tinnitus Center at the Nofer Institute of Occupational Medicine--earliest experience]
    Wojciech J Guzek
    Ośrodka Diagnostyki i Leczenia Szumów Usznych, Łodzi
    Med Pr 53:461-4. 2002
    ..b>Hyperacusis was diagnosed in 16 cases...
  76. ncbi [Recruitment in presbycusis]
    E Sanchez Legaza
    Servicio ORL, Hospital del Sas de la Línea, Cadiz
    An Otorrinolaringol Ibero Am 33:183-91. 2006
    ..We analyse variables and their possible interrelations with recruitment in 241 presbycusic patients...
  77. ncbi The prevalence of premonitory symptoms in migraine: a questionnaire study in 461 patients
    G G Schoonman
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Cephalalgia 26:1209-13. 2006
    ..In conclusion, premonitory symptoms are frequently reported by migraine patients. Sensitivity and specificity of premonitory symptoms for migraine need to be assessed using prospective methods...
  78. ncbi [Migrainous aura subtypes in hospitalized children]
    Agnieszka Biedrón
    Katedra Neurologii Dzieci i Młodziezy, Uniwersytet Jagielloński Collegium Medicum, Krakow
    Przegl Lek 66:952-7. 2009
    ..Knowledge of migraine with aura symptoms, clinical differences associated with developmental age and features enabling differentiation with other disorders imitating migraine is very important...
  79. ncbi Intravenous magnesium sulfate rapidly alleviates headaches of various types
    A Mauskop
    Department of Neurology, State University of New York, Health Science Center at Brooklyn 11203, USA
    Headache 36:154-60. 1996
    ..Measurement of serum IMg2+ levels may have a practical application in many types of headache patients. Low serum and brain tissue ionized magnesium levels may precipitate headache symptoms in susceptible patients...
  80. ncbi Comparison of intravenous valproate versus intramuscular dihydroergotamine and metoclopramide for acute treatment of migraine headache
    K R Edwards
    Western New England Pain and Headache Center, Southwestern Vermont Medical Center, Bennington, VT 05201, USA
    Headache 41:976-80. 2001
    ..Relative to dihydroergotamine/metoclopramide, however, headache relief was not as likely to be sustained at 24 hours as with intravenous valproate...
  81. ncbi Sumatriptan. A pharmacoeconomic review of its use in migraine
    A J Coukell
    Adis International Limited, Auckland, New Zealand
    Pharmacoeconomics 11:473-90. 1997
    ..However, few economic data from well controlled prospective comparisons of sumatriptan with other available agents are available to quantify the effect of sumatriptan on the overall cost of migraine...
  82. ncbi Early intervention in migraine with sumatriptan tablets 50 mg versus 100 mg: a pooled analysis of data from six clinical trials
    Paul Winner
    Palm Beach Headache Center, Premiere Research Institute, 5205 Greenwood Avenue, Ste 200, West Palm Beach, FL 33407, USA
    Clin Ther 27:1785-94. 2005
    ..In clinical trials evaluating sumatriptan in the treatment of moderate or severe migraine pain, the 50- and 100-mg doses have been comparably effective and well tolerated...
  83. ncbi Sumatriptan. An updated review of its use in migraine
    C M Perry
    Adis International Limited, Auckland, New Zealand
    Drugs 55:889-922. 1998
    ..14% of patients with migraine treated with sumatriptan. As the drug is associated with the rare development of cardiovascular effects, it is contraindicated in patients with a history of cardiovascular disease...
  84. ncbi Sumatriptan-naproxen for acute treatment of migraine: a randomized trial
    Jan Lewis Brandes
    Nashville Neuroscience Group, Nashville, Tenn 37203, USA
    JAMA 297:1443-54. 2007
    ..Multiple pathogenic mechanisms may be involved in generating the migraine symptom complex, and multimechanism-targeted therapy may confer advantages over monotherapy...
  85. ncbi Prevalence of migraine in schoolchildren and some clinical comparisons between migraine with and without aura
    I Mavromichalis
    Second Paediatric Department, Aristotelian University of Thessaloniki (Greece, AHEPA General Hospital
    Headache 39:728-36. 1999
    ....
  86. ncbi Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study
    G Geraud
    Service de Neurologie, CHU de Rangueil, Toulouse, France
    Eur Neurol 47:88-98. 2002
    ....
  87. ncbi Topiramate versus amitriptyline in migraine prevention: a 26-week, multicenter, randomized, double-blind, double-dummy, parallel-group noninferiority trial in adult migraineurs
    David W Dodick
    Mayo Clinic Hospital, Phoenix, Arizona 85054, USA
    Clin Ther 31:542-59. 2009
    ..The primary objective of this study was to compare the efficacy and tolerability of topiramate and amitriptyline in the prophylaxis of episodic migraine headache...
  88. ncbi Efficacy of sumatriptan tablets in migraineurs self-described or physician-diagnosed as having sinus headache: a randomized, double-blind, placebo-controlled study
    Gary Ishkanian
    Elkind Headache Center, Mount Vernon, New York 10550, USA
    Clin Ther 29:99-109. 2007
    ..Many patients and physicians interpret episodic headache in the presence or absence of nasal symptoms as "sinus' headache, while ignoring the possible diagnosis of migraine...
  89. ncbi Acute management of migraine
    Debashish Chowdhury
    G B Pant Hospital, New Delhi, India
    J Assoc Physicians India 58:21-5. 2010
    ..Ergots are slowly being replaced by triptans. This is because of their adverse side-effects, low bioavailability and high potential for abuse that can lead to overuse headache...
  90. ncbi A practical guide to the management and prevention of migraine
    H C Diener
    Department of Neurology, University of Essen, Germany
    Drugs 56:811-24. 1998
    ..The efficacy of aspirin or magnesium is still under evaluation...
  91. ncbi Zolmitriptan: a review of its use in migraine
    C M Spencer
    Adis International Limited, Auckland, New Zealand
    Drugs 58:347-74. 1999
    ..The most common adverse events with zolmitriptan therapy are asthenia, heaviness other than that of the chest or neck, dry mouth, nausea, dizziness, somnolence, paraesthesia, warm sensation, tightness, vasodilation and chest pain...
  92. ncbi The prophylactic effect of valproate on glyceryltrinitrate induced migraine
    J F Tvedskov
    Danish Headache Centre, University of Copenhagen
    Cephalalgia 24:576-85. 2004
    ..The size of the effect was similar to that of valproate in clinical trials. The GTN model may therefore be a valid tool for testing new prophylactic antimigraine drugs...
  93. ncbi Noise-induced cell death in the mouse medial geniculate body and primary auditory cortex
    Dietmar Basta
    Department of Otolaryngology at UKB, Free University of Berlin, Warener Str 7, 12683 Berlin, Germany
    Neurosci Lett 381:199-204. 2005
    ..g. tinnitus, recruitment, reduced speech intelligibility, hyperacusis. There are few reports on central noise effects...
  94. ncbi Almotriptan: a review of its use in migraine
    Susan J Keam
    Adis International Limited, Mairangi Bay, Auckland, New Zealand
    Drugs 62:387-414. 2002
    ..Almotriptan can be coadministered with drugs that share a common hepatic metabolic path; in addition, dosage reduction is required only in the presence of severe renal or hepatic impairment...
  95. ncbi Effect of early intervention with almotriptan vs placebo on migraine-associated functional disability: results from the AEGIS Trial
    Frederick Freitag
    Diamond Headache Clinic, Ltd, Chicago, IL, USA
    Headache 48:341-54. 2008
    ..To investigate the effect of early acute migraine intervention with almotriptan vs placebo on functional disability and health-related quality of life (HRQoL) indicators...
  96. ncbi [Differential diagnosis between vertigo of posterior circulation ischemia and migrainous vertigo]
    Ziming Wu
    Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, the Otolaryngology Institute of Chinese PLA, Beijing, 100853, China
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 21:721-3. 2007
    ..To analyze two groups of patients with migrainous vertigo (MV )and vertigo resulting from posterior circulation ischemia (PCIV) and investigate the differential diagnosis between them...
  97. ncbi Topiramate treatment of chronic migraine: a randomized, placebo-controlled trial of quality of life and other efficacy measures
    Stephen Silberstein
    Thomas Jefferson University, Department of Neurology, Philadelphia, PA 19107, USA
    Headache 49:1153-62. 2009
    ..To define yet more clearly the utility of topiramate in the treatment of chronic migraine, we evaluated prespecified secondary endpoints from a recent randomized, double-blind, placebo-controlled, multicenter clinical trial...
  98. pmc Acute endolymphatic hydrops generated by exposure of the ear to nontraumatic low-frequency tones
    Alec N Salt
    Department of Otolaryngology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Assoc Res Otolaryngol 5:203-14. 2004
    Low-frequency sounds presented at high nontraumatizing levels induce temporary hyperacusis in humans and animals. One explanation of this finding is that the basilar membrane operating point may be disturbed by an endolymph volume change...
  99. ncbi Neurobiology in primary headaches
    Lars Edvinsson
    Department of Internal Medicine, University Hospital, S 221 85 Lund, Sweden
    Brain Res Brain Res Rev 48:438-56. 2005
    ..These data suggest a central role for sensory and parasympathetic mechanisms in the pathophysiology of primary headaches. The positive clinical trial with a CGRP receptor antagonist offers a new promising way of treatment...
  100. ncbi Botulinum toxin in migraine prophylaxis
    Hartmut Gobel
    Neurologisch verhaltensmedizinische Schmerzklinik Kiel, Heikendorfer Weg 9 27, 24149 Kiel, Germany
    J Neurol 251:I8-11. 2004
    ....
  101. ncbi Neural changes in the auditory cortex of awake guinea pigs after two tinnitus inducers: salicylate and acoustic trauma
    A J Noreña
    Universite de Provence, CNRS UMR 6149, Marseille, France
    Neuroscience 166:1194-209. 2010
    ..These alterations of cortical response amplitudes likely reflect associated hypoacusis and hyperacusis. The effects of salicylate administration and noise trauma on spontaneous activity were also studied...

Research Grants26

  1. Intervention for Reduced Sound Tolerance
    C Formby; Fiscal Year: 2006
    ..e., hyperacusis) for hearing impaired persons...
  2. Vestibular Recovery after Intratympanic Gentamicin
    John Carey; Fiscal Year: 2004
    ..Furthermore, the mechanisms of vestibular recovery may help us understand the potential for the inner ear to recover from a variety of injuries. ..
  3. Mechanism of Medication Overuse Headache and Chronic Migraine Pain
    Frank Porreca; Fiscal Year: 2013
    ..Understanding such mechanisms may give insight into underlying pathophysiology of medication overuse headache and chronic migraine and of migraine pathophysiology. ..
  4. ANATOMY OF THE AUDITORY SYSTEM
    DONALD KENT MOREST; Fiscal Year: 2010
    ..The overall hypothesis is that these shifts provide a structural basis for tinnitus and hyperacusis after noise exposure...
  5. From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
    Peter M Narins; Fiscal Year: 2010
    ..Ultimately, our research may lead to new therapeutic approaches to treatment of hyperacusis and noise-induced tinnitus, two known syndromes in which efferent system malfunction has been implicated.
  6. SINGLE-NEURON MARKING IN THE STUDY OF ABNORMAL COCHLEAS
    M Charles Liberman; Fiscal Year: 2013
    ..especially in the absence of olivocochlear (OC) feedback, and that selective low-SR fiber loss may lead to hyperacusis, tinnitus and hyperactivity in central circuits...
  7. Functional Networks in Migraine
    Todd Schwedt; Fiscal Year: 2013
    ....
  8. Sensorimotor gating in humans with tinnitus and hyperacusis
    JENNIFER RENEE MELCHER; Fiscal Year: 2013
    ..gating - the acoustic startle response (ASR) and prepulse inhibition (PPI) - in humans with tinnitus and hyperacusis is both important and timely...
  9. Excitability and synaptic function of type II cochlear afferents
    Paul Fuchs; Fiscal Year: 2013
    ..Hearing loss can lead to hyperacusis and the phantom percept of tinnitus...
  10. Serotonin receptors in the inferior colliculus
    Laura Hurley; Fiscal Year: 2006
    ..the auditory behaviors and pathologies in which serotonin is thought to play a role, including auditory gating, hyperacusis, and tinnitus...
  11. Development of a rapid behavioral tinnitus screen for rats.
    Jeremy Turner; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  12. Peripherial and Central Mechanisms of Tinnitus Generat
    Carol Bauer; Fiscal Year: 2006
    ..Safe and efficacious therapy for this prevalent and often debilitating problem can only occur with improved understanding of the disorder. ..
  13. Auditory Plasticity in the Aged Mouse
    Jeremy Turner; Fiscal Year: 2005
    ..abstract_text> ..
  14. CERVICAL INFLUENCES ON BALANCE
    Joseph Furman; Fiscal Year: 2003
    ..To address specific aim #3, postural sway will be measured in response to naso-occipital optic flow within a virtual reality environment during several yaw head-on-trunk positions. ..
  15. VESTIBULO-OCULAR FUNCTION IN THE ELDERLY
    Joseph Furman; Fiscal Year: 2009
    ..Taken together, these studies will provide essential information regarding the influence of aging on several specific aspects of balance and thus may have practical implications regarding the management of age-related loss of balance. ..
  16. Migraine Pathophysiology:Thalamus and Extended Allodynia
    Rami Burstein; Fiscal Year: 2009
    ....
  17. Signal Processing in Audition
    Fan Gang Zeng; Fiscal Year: 2009
    ..abstract_text> ..
  18. SPECTRAL CUES FOR SOUND LOCALIZATION
    Bradford May; Fiscal Year: 2008
    ..Consequently, this research will enhance our current understanding of the processes and perceptions that shape directional hearing, speech processing, and compensation for hearing loss in humans. [unreadable] [unreadable]..
  19. DRUG AND NON-DRUG TREATMENT OF SEVERE MIGRAINES
    Kenneth Holroyd; Fiscal Year: 2004
    ....
  20. VESTIBULAR EFFECTS OF INTRATYMPANIC GENTAMICIN
    John Carey; Fiscal Year: 2005
    ..Johns Hopkins is uniquely suited to this training because it has a core group devoted to vestibular research, and the mentor's laboratory has successfully used all of the techniques required. ..
  21. Problems and Competence under Age5: School Transition
    Alice Carter; Fiscal Year: 2005
    ....
  22. Evalution of Vestibular Function in Meniere's Disease
    John Carey; Fiscal Year: 2009
    ..Comparisons of angular and translational VOR deficits after intratympanic gentamicin should demonstrate whether or not the utricle is less susceptible than the semicircular canals to intratympanic gentamicin. ..
  23. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  24. Auditory processing of signals in noise
    Bradford May; Fiscal Year: 2006
    ..A better understanding of the brain's signal processing solutions will lead to improved designs for assistive listening devices that now show poor performance in noisy environments. ..
  25. NEUROBIOLOGY OF ANOREXIA INDUCED BY MIGRAINE PAIN
    Rami Burstein; Fiscal Year: 2004
    ..abstract_text> ..
  26. Gene Expression in Acute and Chronic Neurologic Disease
    Donald Gilden; Fiscal Year: 2008
    ..This concerted effort is focused on prospective studies to delineate the cause, pathogenesis and eventual prevention of viral and demyelinating diseases of the human nervous system. ..