Summary: An imbalanced nutritional status resulted from insufficient intake of nutrients to meet normal physiological requirement.

Top Publications

  1. ncbi The World Health Organization Global Database on Child Growth and Malnutrition: methodology and applications
    Mercedes de Onis
    Department of Nutrition for Health and Development, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    Int J Epidemiol 32:518-26. 2003
  2. doi Maternal and child undernutrition: global and regional exposures and health consequences
    Robert E Black
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 371:243-60. 2008
  3. pmc Maternal and child undernutrition: consequences for adult health and human capital
    Cesar G Victora
    Universidade Federal de Pelotas, Pelotas, Brazil
    Lancet 371:340-57. 2008
  4. ncbi Bacteremia among children admitted to a rural hospital in Kenya
    James A Berkley
    Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    N Engl J Med 352:39-47. 2005
  5. ncbi A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease
    D Fouque
    Department of Nephrology, Hopital Edouard Herriot, Universite Lyon 1, U870 INSERM, Lyon, France
    Kidney Int 73:391-8. 2008
  6. ncbi ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
    Tatsuo Hashimoto
    IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, 1030 Vienna, Austria
    Nature 487:477-81. 2012
  7. ncbi The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals
    J P Cegielski
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA
    Int J Tuberc Lung Dis 8:286-98. 2004
  8. pmc HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria
    James A Berkley
    Centre for Geographic Medicine Research, Kilifi, Kenya
    Clin Infect Dis 49:336-43. 2009
  9. ncbi Role of premature leptin surge in obesity resulting from intrauterine undernutrition
    Shigeo Yura
    Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara cho Sakyo ku, Kyoto 606 8507, Japan
    Cell Metab 1:371-8. 2005
  10. ncbi Food insecurity is associated with nutrient inadequacies among Canadian adults and adolescents
    Sharon I Kirkpatrick
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON M5S 3E2
    J Nutr 138:604-12. 2008

Detail Information

Publications298 found, 100 shown here

  1. ncbi The World Health Organization Global Database on Child Growth and Malnutrition: methodology and applications
    Mercedes de Onis
    Department of Nutrition for Health and Development, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    Int J Epidemiol 32:518-26. 2003
    ..surveys have been conducted using various definitions, indicators and reference populations to classify child malnutrition. The World Health Organization (WHO) Global Database on Child Growth and Malnutrition was initiated in 1986 ..
  2. doi Maternal and child undernutrition: global and regional exposures and health consequences
    Robert E Black
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet 371:243-60. 2008
  3. pmc Maternal and child undernutrition: consequences for adult health and human capital
    Cesar G Victora
    Universidade Federal de Pelotas, Pelotas, Brazil
    Lancet 371:340-57. 2008
    ..Its prevention will probably bring about important health, educational, and economic benefits. Chronic diseases are especially common in undernourished children who experience rapid weight gain after infancy...
  4. ncbi Bacteremia among children admitted to a rural hospital in Kenya
    James A Berkley
    Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    N Engl J Med 352:39-47. 2005
    ..We studied every acute pediatric admission to a rural district hospital in Kenya to examine the prevalence, incidence, types, and outcome of community-acquired bacteremia...
  5. ncbi A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease
    D Fouque
    Department of Nephrology, Hopital Edouard Herriot, Universite Lyon 1, U870 INSERM, Lyon, France
    Kidney Int 73:391-8. 2008
    The recent research findings concerning syndromes of muscle wasting, malnutrition, and inflammation in individuals with chronic kidney disease (CKD) or acute kidney injury (AKI) have led to a need for new terminology...
  6. ncbi ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
    Tatsuo Hashimoto
    IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, 1030 Vienna, Austria
    Nature 487:477-81. 2012
    b>Malnutrition affects up to one billion people in the world and is a major cause of mortality. In many cases, malnutrition is associated with diarrhoea and intestinal inflammation, further contributing to morbidity and death...
  7. ncbi The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals
    J P Cegielski
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA
    Int J Tuberc Lung Dis 8:286-98. 2004
    The oral traditions of medicine and public health have it that malnutrition is an important risk factor for the development of tuberculosis (TB)...
  8. pmc HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria
    James A Berkley
    Centre for Geographic Medicine Research, Kilifi, Kenya
    Clin Infect Dis 49:336-43. 2009
    Human immunodeficiency virus (HIV) infection, malnutrition, and invasive bacterial infection (IBI) are reported among children with severe malaria...
  9. ncbi Role of premature leptin surge in obesity resulting from intrauterine undernutrition
    Shigeo Yura
    Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara cho Sakyo ku, Kyoto 606 8507, Japan
    Cell Metab 1:371-8. 2005
    ..The present study suggests that the premature leptin surge alters energy regulation by the hypothalamus and contributes to "developmental origins of health and disease."..
  10. ncbi Food insecurity is associated with nutrient inadequacies among Canadian adults and adolescents
    Sharon I Kirkpatrick
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON M5S 3E2
    J Nutr 138:604-12. 2008
    ..These findings highlight the need for concerted public policy responses to ameliorate household food insecurity...
  11. ncbi Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles
    Laura E Caulfield
    Department of International Health, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Clin Nutr 80:193-8. 2004
    ..Previous analyses derived the relative risk (RR) of dying as a result of low weight-for-age and calculated the proportion of child deaths worldwide attributable to underweight...
  12. ncbi Mechanisms of nutrient modulation of the immune response
    Susanna Cunningham-Rundles
    Host Defenses Program, Department of Pediatrics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY, USA
    J Allergy Clin Immunol 115:1119-28; quiz 1129. 2005
    ..Nutrients act as antioxidants and as cofactors at the level of cytokine regulation. Protein calorie malnutrition and zinc deficiency activate the hypothalamic-pituitary-adrenal axis...
  13. pmc Conceptual framework for understanding the bidirectional links between food insecurity and HIV/AIDS
    Sheri D Weiser
    Division of HIV AIDS, San Francisco General Hospital, USA
    Am J Clin Nutr 94:1729S-1739S. 2011
    ..More research on the relative importance of each of these pathways is warranted because effective interventions to reduce food insecurity and HIV depend on a rigorous understanding of these multifaceted relationships...
  14. ncbi The interaction between nutrition and infection
    Peter Katona
    The David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
    Clin Infect Dis 46:1582-8. 2008
    Infection and malnutrition have always been intricately linked. Malnutrition is the primary cause of immunodeficiency worldwide, and we are learning more and more about the pathogenesis of this interaction...
  15. pmc Severe malnutrition with and without HIV-1 infection in hospitalised children in Kampala, Uganda: differences in clinical features, haematological findings and CD4+ cell counts
    Hanifa Bachou
    Department of Paediatrics and Child Health, Makerere University Medical School, P O Box 7072, Kampala, Uganda
    Nutr J 5:27. 2006
    ..The aim of this study was to describe the clinical features, haematological findings and CD4+ and CD8+ cell counts of severely malnourished children in relation to human immunodeficiency virus (HIV) infection...
  16. pmc Childhood tuberculosis and malnutrition
    Devan Jaganath
    David Geffen School of Medicine at the University of California, Los Angeles, USA
    J Infect Dis 206:1809-15. 2012
    Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship...
  17. pmc Contribution of enteric infection, altered intestinal barrier function, and maternal malnutrition to infant malnutrition in Bangladesh
    Dinesh Mondal
    International Centre for Diarrhoeal Disease Research, Laboratory Sciences Division, Dhaka, Bangladesh
    Clin Infect Dis 54:185-92. 2012
    ..Our goal was to determine the contribution of specific enteric infections to malnutrition-associated diarrhea and to determine the role of enteric infections in the development of malnutrition.
  18. ncbi The economic impact of disease-related malnutrition at hospital admission
    Teresa F Amaral
    Faculty of Nutrition and Food Sciences, University of Porto, Portugal
    Clin Nutr 26:778-84. 2007
    The reported frequency of disease-related malnutrition (DRM) for patients admitted to hospitals has been shown to be high, but an accurate estimate of the magnitude of its economic costs is lacking...
  19. pmc Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
    Asgeir Johannessen
    Department of Infectious Diseases, Ulleval University Hospital, Oslo, Norway
    BMC Infect Dis 8:52. 2008
    ..Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania...
  20. ncbi The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis
    M Isabel T D Correia
    Department of Surgery, Faculdade de Medicina da, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Clin Nutr 22:235-9. 2003
    b>Malnutrition has been identified as affecting patient outcome. The purpose of this study was to correlate the nutritional status of hospitalized patients with their morbidity, mortality, length of hospital stay and costs...
  21. ncbi Pneumonia in severely malnourished children in developing countries - mortality risk, aetiology and validity of WHO clinical signs: a systematic review
    Mohammod Jobayer Chisti
    Clinical Science Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Trop Med Int Health 14:1173-89. 2009
    To quantify the degree by which moderate and severe degrees of malnutrition increase the mortality risk in pneumonia, to identify potential differences in the aetiology of pneumonia between children with and without severe malnutrition, ..
  22. pmc Mapping the risk of anaemia in preschool-age children: the contribution of malnutrition, malaria, and helminth infections in West Africa
    Ricardo J Soares Magalhães
    School of Population Health, University of Queensland, Herston, Queensland, Australia
    PLoS Med 8:e1000438. 2011
    ..The aim was to estimate the geographical risk profile of anaemia accounting for malnutrition, malaria, and helminth infections, the risk of anaemia attributable to these factors, and the number of anaemia ..
  23. pmc Malnutrition and infection: complex mechanisms and global impacts
    Ulrich E Schaible
    London School of Hygiene and Tropical Medicine, Department of Infectious and Tropical Diseases, Immunology Unit, London, United Kingdom
    PLoS Med 4:e115. 2007
  24. ncbi Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya
    Mike English
    KEMRI Centre for Geographic Medicine Research, PO Box 230, Kilifi, Kenya
    Lancet 363:1948-53. 2004
    ..The district hospital is considered essential for delivering basic, cost-effective health care to children in resource poor countries. We aimed to investigate the performance of these facilities in Kenya...
  25. pmc Socioeconomic inequalities in childhood undernutrition in India: analyzing trends between 1992 and 2005
    Malavika A Subramanyam
    Center for Integrative Approaches to Health Disparities, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 5:e11392. 2010
    ..We examined the trends in social disparities in underweight and stunting among Indian children aged less than three years using nationally representative data...
  26. ncbi The politics of reducing malnutrition: building commitment and accelerating progress
    Stuart Gillespie
    International Food Policy Research Institute, Washington, DC 20006 1002, USA
    Lancet 382:552-69. 2013
    ..Harmonisation has increased among stakeholders, with regard to their understanding of the main causes of malnutrition and to the various options for addressing it...
  27. pmc Prenatal malnutrition and adult schizophrenia: further evidence from the 1959-1961 Chinese famine
    Ming Qing Xu
    Bio X Life Science Research Center, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, PR China
    Schizophr Bull 35:568-76. 2009
    ..We tested the hypothesis in a second Chinese population and also determined whether risk differed between urban and rural areas...
  28. ncbi Association of Malnutrition-Inflammation Score with quality of life and mortality in hemodialysis patients: a 5-year prospective cohort study
    Mehdi Rambod
    Harold Simmons Center for Kidney Disease Research and Epidemiology, CA, USA
    Am J Kidney Dis 53:298-309. 2009
    The Malnutrition-Inflammation Score (MIS), an inexpensive and easy-to-assess score of 0 to 30 to examine protein-energy wasting (PEW) and inflammation, includes 7 components of the Subjective Global Assessment, body mass index, and serum ..
  29. ncbi Relations between malnutrition-inflammation-atherosclerosis and volume status. The usefulness of bioimpedance analysis in peritoneal dialysis patients
    Meltem Sezis Demirci
    Division of Nephrology, Ege University School of Medicine, Izmir, Turkey
    Nephrol Dial Transplant 26:1708-16. 2011
    ..In addition, we analysed the relationship of extracellular volume values by m-BIA to echocardiographic parameters in order to define its usefulness as a measure of FO...
  30. ncbi International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control
    Kenneth H Brown
    Program in International Nutrition, University of California, Davis, USA
    Food Nutr Bull 25:S99-203. 2004
  31. ncbi Prevalence of malnutrition in Parkinson's disease: a systematic review
    Jamie M Sheard
    Movement Neuroscience Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
    Nutr Rev 69:520-32. 2011
    Parkinson's disease (PD) patients may be at higher risk of malnutrition because of the symptoms associated with the disease and the side effects of the medication used to manage it...
  32. ncbi Maternal and child undernutrition: effective action at national level
    Jennifer Bryce
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Lancet 371:510-26. 2008
    ..This resource needs to be formalised, shared, and used as the basis for setting priorities in problem-solving research for nutrition...
  33. ncbi Serum albumin, C-reactive protein, interleukin 6, and fetuin a as predictors of malnutrition, cardiovascular disease, and mortality in patients with ESRD
    Hirokazu Honda
    Division of Renal Medicine, Department of Clinical Science, Interventions and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Kidney Dis 47:139-48. 2006
    Serum albumin (S-Alb), C-reactive protein (CRP), and interleukin 6 (IL-6) predict malnutrition, atherosclerotic cardiovascular disease (CVD), and mortality in patients with end-stage renal disease (ESRD)...
  34. ncbi Clinical outcomes of severe malnutrition in a high tuberculosis and HIV setting
    Tim De Maayer
    Rahima Moosa Mother and Child Hospital, Department of Paediatrics and Child Health, University of the Witwatersrand, Newclare 2112, Johannesburg, South Africa
    Arch Dis Child 96:560-4. 2011
    Case death rates for severe childhood malnutrition remain stubbornly elevated in high HIV prevalence settings, despite the implementation of WHO guidelines...
  35. pmc Prevalence and determinants of chronic malnutrition among preschool children: a cross-sectional study in Dhaka City, Bangladesh
    Aklima Jesmin
    Medicine Sans Frontires Belgium, Dhaka, Bangladesh
    J Health Popul Nutr 29:494-9. 2011
    Chronic malnutrition is one of the major causes of morbidity and mortality among preschool children and the future productivity of nations...
  36. ncbi Perioperative nutrition in malnourished surgical cancer patients - a prospective, randomized, controlled clinical trial
    Stanislaw Klek
    Stanley Dudrick s Memorial Hospital, General Surgery Unit, 15 Tyniecka Street, 32 050 Skawina, Poland
    Clin Nutr 30:708-13. 2011
    ..The aim of the study was to evaluate the clinical value of the route and type of perioperative nutritional support...
  37. ncbi Impact of malnutrition and social determinants on survival of HIV-infected adults starting antiretroviral therapy in resource-limited settings
    Xavier Argemi
    Department of Infectious Diseases, Nouvel Hopital Civil, Strasbourg, France
    AIDS 26:1161-6. 2012
    Determining the impact of malnutrition, anaemia and social determinants on survival once starting antiretroviral therapy (ART) in a cohort of HIV-infected adults in a rural HIV care centre in Sihanoukville, Cambodia.
  38. pmc Malnutrition in a sample of community-dwelling people with Parkinson's disease
    Jamie M Sheard
    School of Exercise and Nutrition Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
    PLoS ONE 8:e53290. 2013
    b>Malnutrition results in poor health outcomes, and people with Parkinson's disease may be more at risk of malnutrition. However, the prevalence of malnutrition in Parkinson's disease is not yet well defined...
  39. pmc A large-scale distribution of milk-based fortified spreads: evidence for a new approach in regions with high burden of acute malnutrition
    Isabelle Defourny
    Medecins Sans Frontieres, Paris, France
    PLoS ONE 4:e5455. 2009
    ..In high burden regions for malnutrition, the treatment of individual children is limited by available resources...
  40. ncbi Comprehensive assessment of malnutrition risk and related factors in a large group of community-dwelling older adults
    Zekeriya Ulger
    Hacettepe University Faculty of Medicine, Department of Internal Medicine, Division of Geriatric Medicine, 06100 Sihhiye, Ankara, Turkey
    Clin Nutr 29:507-11. 2010
    Older adults are poorly assessed for malnutrition risk although malnutrition is not an uncommon problem in this population. The aim of this study was to determine the malnutrition risk and its correlates in geriatric outpatients.
  41. ncbi Who will become malnourished? A prospective study of factors associated with malnutrition in older persons living at home
    L Johansson
    Department of Nursing Science, School of Health Sciences, Jonkoping University, Sweden
    J Nutr Health Aging 13:855-61. 2009
    ..To describe the nutritional status of older persons living at home, to investigate factors of importance for nutritional status, and to describe possible relationships between nutritional status and health-related quality of life (HRQoL)...
  42. ncbi Frequency of malnutrition in older adults: a multinational perspective using the mini nutritional assessment
    Matthias J Kaiser
    Institute for Biomedicine of Aging, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    J Am Geriatr Soc 58:1734-8. 2010
    To provide pooled data on the prevalence of malnutrition in elderly people as evaluated using the Mini Nutritional Assessment (MNA).
  43. ncbi Associations of serum fetuin-A with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients
    Angela Yee Moon Wang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Nephrol Dial Transplant 20:1676-85. 2005
    ..However, its relationships with cardiac valvular calcification and atherosclerosis and outcome have not been evaluated in peritoneal dialysis (PD) patients...
  44. ncbi Programs to improve production and consumption of animal source foods and malnutrition in Vietnam
    Le Thi Hop
    National Institute of Nutrition, Ministry of Health, Hanoi, Vietnam
    J Nutr 133:4006S-4009S. 2003
    ..The prevalence of undernutrition in children <5 y old, and of chronic energy deficiency (CED) in women of reproductive age, has been remarkably reduced...
  45. ncbi Prognostic impact of disease-related malnutrition
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Nutr 27:5-15. 2008
    This review focuses on the studies investigating the prognostic implications of disease-related malnutrition. Malnutrition is a common problem in patients with chronic or severe diseases...
  46. ncbi Malnutrition in a home-living older population: prevalence, incidence and risk factors. A prospective study
    Yvonne Johansson
    Department of Medical and Health Sciences, Division of Nursing Science, Faculty of Health Science, Linkoping University, Linkoping, Sweden
    J Clin Nurs 18:1354-64. 2009
    To prospectively investigate and describe the prevalence and incidence of malnutrition among home-living older people, related to demographic and medical factors, self-perceived health and health-related quality of life...
  47. ncbi Urinary arsenic concentration adjustment factors and malnutrition
    Barbro Nermell
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Res 106:212-8. 2008
    ..1466 individuals, 5-88 years of age, in Matlab, rural Bangladesh, where arsenic-contaminated drinking water and malnutrition are prevalent (about 30% of the adults had body mass index (BMI) below 18.5 kg/m(2))...
  48. pmc Children with severe malnutrition: can those at highest risk of death be identified with the WHO protocol?
    Kathryn Maitland
    Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
    PLoS Med 3:e500. 2006
    With strict adherence to international recommended treatment guidelines, the case fatality for severe malnutrition ought to be less than 5%...
  49. ncbi ESPEN Guidelines on Parenteral Nutrition: surgery
    M Braga
    Department of Surgery, San Raffaele University, Milan, Italy
    Clin Nutr 28:378-86. 2009
    ..In those patients who are unable to be fed via the enteral route after surgery, and in whom total or near total parenteral nutrition is required, a full range of vitamins and trace elements should be supplemented on a daily basis...
  50. ncbi Poverty, obesity, and malnutrition: an international perspective recognizing the paradox
    Sherry A Tanumihardjo
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Am Diet Assoc 107:1966-72. 2007
    ..Therefore, we need to take heed of the double burden of malnutrition caused by poverty, hunger, and food insecurity...
  51. ncbi Bioimpedance-based identification of malnutrition using fuzzy logic
    S Wieskotten
    Technische Universitat Darmstadt, Institute of Automatic Control, Darmstadt, Germany
    Physiol Meas 29:639-54. 2008
    Protein-energy malnutrition reduces the quality of life, lengthens the time in hospital and dramatically increases mortality...
  52. ncbi Anthropometry as a tool for measuring malnutrition: impact of the new WHO growth standards and reference
    M B Duggan
    Department of Paediatrics and Child Health, Mbarara, Uganda College of Medicine, Blantyre, Malawi
    Ann Trop Paediatr 30:1-17. 2010
    ..agreed growth standards in 1983 facilitated comparative nutritional assessment and the grading of childhood malnutrition. New growth standards for children under 5 years and growth reference for children aged 5-19 years have ..
  53. ncbi Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition
    Yongmei Liu
    Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 291:451-9. 2004
    ..This paradox may be explained by systemic inflammation and/or malnutrition, which are associated with lower cholesterol levels and higher mortality.
  54. ncbi The impact of malnutrition on survival and the CD4 count response in HIV-infected patients starting antiretroviral therapy
    N I Paton
    Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore
    HIV Med 7:323-30. 2006
    The impact that malnutrition at the time of starting antiretroviral therapy (ART) has on survival and the CD4 count response is not known.
  55. pmc Poverty, child undernutrition and morbidity: new evidence from India
    Shailen Nandy
    School for Policy Studies, University of Bristol, Bristol, England
    Bull World Health Organ 83:210-6. 2005
  56. ncbi Massive increase, spread, and exchange of extended spectrum β-lactamase-encoding genes among intestinal Enterobacteriaceae in hospitalized children with severe acute malnutrition in Niger
    Paul Louis Woerther
    French National Reference Center for Bacterial Resistance in Commensal Flora, Laboratory of Bacteriology, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris
    Clin Infect Dis 53:677-85. 2011
    ..Although their dissemination appears linked to Escherichia coli intestinal carriage, precise paths of this dynamic are largely unknown...
  57. pmc Global burden of double malnutrition: has anyone seen it?
    Daniel J Corsi
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada
    PLoS ONE 6:e25120. 2011
    ..Low- to middle-income countries (LMICs) are believed to be characterized by the coexistence of underweight and overweight. It has also been posited that such coexistence is appearing among the low socioeconomic status (SES) groups...
  58. pmc Nutritional status and functional capacity of hospitalized elderly
    Maria R M Oliveira
    Institute of Biosciences, UNESP Sao Paulo State University, Botucatu, Brazil
    Nutr J 8:54. 2009
    ..We asses the relationship between nutritional status and indicators of functional capacity among recently hospitalized elderly in a general hospital...
  59. ncbi Estimating the costs associated with malnutrition in Dutch nursing homes
    Judith M M Meijers
    Department of Health Services Research, School for Public Heath and Primary Care CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Clin Nutr 31:65-8. 2012
    b>Malnutrition in western health care involves a tremendous burden of illness...
  60. ncbi Socioeconomic status and chronic child malnutrition: Wealth and maternal education matter more in the Peruvian Andes than nationally
    Helga B Urke
    Department of Health Promotion and Development, Faculty of Psychology, University of Bergen, Bergen, Norway
    Nutr Res 31:741-7. 2011
    ..b>Malnutrition was measured using the indicator "stunting," which is small stature for age...
  61. pmc Undernutrition among HIV-positive children in Dar es Salaam, Tanzania: antiretroviral therapy alone is not enough
    Bruno F Sunguya
    Department of Community and Global Health, Graduate School of Medicine, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Public Health 11:869. 2011
  62. ncbi Childhood malnutrition and growth in a rural area of Western Kenya
    Samantha Semproli
    Dipartimento Biologia Evoluzionistica Sper, Universita degli Studi, Bologna, Italy
    Am J Phys Anthropol 132:463-9. 2007
    ..patterns of growth and nutritional status of the Luo population by assessment of the prevalence and trends of malnutrition among children and adolescents...
  63. ncbi The double burden of malnutrition and cardiometabolic risk widens the gender and socio-economic health gap: a study among adults in Burkina Faso (West Africa)
    Augustin N Zeba
    Departement de Nutrition, Faculte de Medecine, Universite de Montreal, Montreal, Quebec, Canada
    Public Health Nutr 15:2210-9. 2012
    To document the double burden of malnutrition and cardiometabolic risk factors (CMRF) in adults and its occurrence according to different sociodemographic parameters.
  64. ncbi Helminths and skewed cytokine profiles increase tuberculin skin test positivity in Warao Amerindians
    L M Verhagen
    Laboratorio de Tuberculosis, Instituto de Biomedicina, Caracas, Venezuela
    Tuberculosis (Edinb) 92:505-12. 2012
    ..We investigated the influence of parasitic infections, malnutrition and plasma cytokine profiles on tuberculin skin test (TST) positivity in Warao Amerindians in Venezuela...
  65. ncbi Predicting the outcome of long-term care by clinical and functional indices: the role of nutritional status
    L M Donini
    Department of Medical Physiopathology Food Science Section Sapienza University of Rome, Italy
    J Nutr Health Aging 15:586-92. 2011
    ..Aim of the study is that of retrospectively verify, through a multivariate analysis, the factors able to condition mortality in long-term care, paying particular attention to the nutritional status...
  66. ncbi Prevalence of the notification of malnutrition in the departments of internal medicine and its prognostic implications
    Javier Marco
    Department of Internal Medicine, Hospital Clinico de San Carlos, Madrid, Spain
    Clin Nutr 30:450-4. 2011
    Detection and notification of malnutrition are essential to adopt a support plan and take costs into account...
  67. ncbi Association of depression with malnutrition in chronic hemodialysis patients
    Ja Ryong Koo
    Department of Internal Medicine, Division of Nephrology, College of Medicine, Hallym University, Chuchon, Kangwon Do, South Korea
    Am J Kidney Dis 41:1037-42. 2003
    ..associated with poor oral intake and activation of proinflammatory cytokines that could further increase mortality by malnutrition, we investigated the relation between depression and nutritional status in chronic hemodialysis patients.
  68. ncbi Strengthening public health nutrition research and training capacities in West Africa: Report of a planning workshop convened in Dakar, Senegal, 26-28 March 2009
    Kenneth H Brown
    Department of Nutrition, University of California Davis, USA
    Glob Public Health 5:S1-19. 2010
  69. pmc 'Rumours' and clinical trials: a retrospective examination of a paediatric malnutrition study in Zambia, southern Africa
    Patricia Kingori
    Anthropologies of African Biosciences, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, Tavistock Place, London WC13 7HT, UK
    BMC Public Health 10:556. 2010
    ..This paper represents a retrospective examination of a malnutrition study conducted by an international team of researchers in Zambia, Southern Africa...
  70. pmc N-terminal proBNP--marker of cardiac dysfunction, fluid overload, or malnutrition in hemodialysis patients?
    John Booth
    Center for Nephrology, Royal Free Hospital, London, UK
    Clin J Am Soc Nephrol 5:1036-40. 2010
    ..However recent reports have suggested that NTproBNP is a marker of volume overload rather than one of cardiac dysfunction. Therefore this study investigated the effect of fluid volume status on NTproBNP...
  71. ncbi Nutritional assessment interpretation on 22,007 Spanish community-dwelling elders through the Mini Nutritional Assessment test
    M Cuervo
    Department of Food Sciences, Nutrition, Physiology and Toxicology, University of Navarra, Irunlarrea 1, E 31080 Pamplona, Spain
    Public Health Nutr 12:82-90. 2009
    ..To evaluate the prevalence of undernutrition among community-dwelling elderly people in Spain using the Mini Nutritional Assessment (MNA) and to analyse its distribution according to age, gender and residence region...
  72. ncbi Malnutrition in the elderly and its relationship with other geriatric syndromes
    Bulent Saka
    Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Millet Cad, Capa, Fatih, Istanbul 34093, Turkey
    Clin Nutr 29:745-8. 2010
    ..Age related decline in food intake is associated with various physiological, psychological and social factors. Our aim was to assess the nutritional status of our elderly patients and its association with other geriatric syndromes...
  73. ncbi Health economic impact of managing patients following a community-based diagnosis of malnutrition in the UK
    Julian F Guest
    CATALYST Health Economics Consultants, Northwood, Middlesex, UK
    Clin Nutr 30:422-9. 2011
    To examine the effect of malnutrition on clinical outcomes and healthcare resource use from initial diagnosis by a general practitioner (GP) in the UK.
  74. pmc The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure
    Leslie P Kozak
    Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    PLoS ONE 5:e11015. 2010
  75. ncbi Evaluation of nutrition assessment tools compared with body cell mass for the assessment of malnutrition in chronic kidney disease
    Katrina L Campbell
    Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia
    J Ren Nutr 17:189-95. 2007
    ..We compared the subjective global assessment (SGA) and a range of SGA-based assessment tools with body cell mass (BCM) in patients with stage IV and V predialysis chronic kidney disease (CKD)...
  76. ncbi Prompt initiation of ART With therapeutic food is associated with improved outcomes in HIV-infected Malawian children with malnutrition
    Maria H Kim
    Baylor College of Medicine International Pediatrics AIDS Initiative at Texas Children s Hospital, Houston, TX, USA
    J Acquir Immune Defic Syndr 59:173-6. 2012
    This retrospective observational study of 140 HIV-infected children with uncomplicated malnutrition in urban Malawi tested the hypothesis that initiation of antiretroviral therapy (ART) within 21 days of outpatient therapeutic feeding (..
  77. pmc Malnutrition affects quality of life in gastroenterology patients
    Kristina Norman
    Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charité Universitätsmedizin Berlin Campus Mitte, Germany
    World J Gastroenterol 12:3380-5. 2006
    To investigate the association between malnutrition and quality of life in patients with benign gastrointestinal disease.
  78. pmc Domestic violence and chronic malnutrition among women and children in India
    Leland K Ackerson
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 167:1188-96. 2008 correlates, but there is little evidence regarding a relation between domestic violence and malnutrition. To investigate this relation, the authors analyzed data from 69,072 women aged 15-49 years and 14,552 children ..
  79. pmc Risk and causes of paediatric hospital-acquired bacteraemia in Kilifi District Hospital, Kenya: a prospective cohort study
    Alexander M Aiken
    Kenya Medical Research Institute Wellcome Trust Research Programme, Kilifi, Kenya
    Lancet 378:2021-7. 2011
    ..In sub-Saharan Africa, community-acquired bacteraemia is an important cause of illness and death in children. Our aim was to establish the magnitude and causes of hospital-acquired (nosocomial) bacteraemia in African children...
  80. ncbi Determinants of nutritional status of older people in long-term care settings on the example of the nursing home in Białystok
    Z B Wojszel
    Department of Geriatrics, Medical University of Białystok, ul Fabryczna 27, 15 471 Białystok, Poland
    Adv Med Sci 51:168-73. 2006
    ..The aim of the study was the assessment of the nutritional status of older people living in the chosen long-term care setting in Poland as well as the determinants having an effect on the nutritional status of the examined subjects...
  81. ncbi Nutritional deficiencies in the developing world: current status and opportunities for intervention
    Yasir Khan
    Division of Women and Child Health, Aga Khan University, Stadium Road, PO Box 3500, Karachi 74800, Pakistan
    Pediatr Clin North Am 57:1409-41. 2010
    ..Three groups of underlying factors contribute to inadequate dietary intake and infectious disease: inadequate maternal and child care, household food insecurity, and poor health services in an unhealthy environment...
  82. ncbi Nutritional status, nutrition practices and post-operative complications in patients with gastrointestinal cancer
    A K Garth
    School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Victoria, Australia
    J Hum Nutr Diet 23:393-401. 2010
    b>Malnutrition and its associated complications are a considerable issue for surgical patients with upper gastrointestinal and colorectal cancer...
  83. ncbi Effectiveness of ready-to-use therapeutic food compared to a corn/soy-blend-based pre-mix for the treatment of childhood moderate acute malnutrition in Niger
    Fabienne Nackers
    Epicentre, Paris, France
    J Trop Pediatr 56:407-13. 2010
    Standard nutritional treatment of moderate acute malnutrition (MAM) relies on fortified blended flours though their importance to treat this condition is a matter of discussion...
  84. ncbi Insufficient nutritional knowledge among health care workers?
    Morten Mowe
    Department of Geriatric Medicine, Aker University Hospital, Trondheimsveien 155, 0514 Oslo, Norway
    Clin Nutr 27:196-202. 2008
    ..The aim of this questionnaire was to study doctors and nurses' self-reported knowledge in nutritional practice, with focus on ESPEN's guidelines in nutritional screening, assessment and treatment...
  85. ncbi Effects of food fortification on nutritional and functional status in frail elderly nursing home residents at risk of malnutrition
    Christine Smoliner
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 24:1139-44. 2008
    b>Malnutrition is a frequent problem in the elderly and is associated with an impaired functional status and higher morbidity and mortality...
  86. pmc Zinc and glutamine improve brain development in suckling mice subjected to early postnatal malnutrition
    Fernando V L Ladd
    Department of Surgery, College of Veterinary Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
    Nutrition 26:662-70. 2010
    ..The effect of zinc and glutamine on brain development was investigated during the lactation period in Swiss mice...
  87. ncbi Obesity as malnutrition: the role of capitalism in the obesity global epidemic
    Jonathan C K Wells
    Childhood Nutrition Research Centre, UCL Institute of Child Health, London, United Kingdom
    Am J Hum Biol 24:261-76. 2012
    ..Prevention policies targeting individual behavior have proved ineffective and economic policies are arguably the optimal target for intervention...
  88. pmc Quality of hospital care for sick newborns and severely malnourished children in Kenya: a two-year descriptive study in 8 hospitals
    David Gathara
    KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
    BMC Health Serv Res 11:307. 2011
    Given the high mortality associated with neonatal illnesses and severe malnutrition and the development of packages of interventions that provide similar challenges for service delivery mechanisms we set out to explore how well such ..
  89. ncbi Perceived health and risk of undernutrition: a comparison of different nutritional screening results in older patients
    Ulrika Söderhamn
    Department of Health and Nursing Sciences, Faculty of Health and Sport Sciences, University of Agder and Centre for Caring Research Southern Norway, Grimstad, Norway
    J Clin Nurs 20:2162-71. 2011
    ..To compare screening results using different nutritional screening instruments with respect to nutritional risk and associations with perceived health and health-related issues in a group of older hospital patients...
  90. ncbi Malnutrition and intestinal parasitic infections in school children of Gondar, North West Ethiopia
    Netsanet Worku
    Department of Nutrition, College of Medicine and Health Sciences, University of Gondar, P O Box 196, Gondar, Ethiopia
    Ethiop Med J 47:9-16. 2009
    In developing countries, malnutrition is a considerable health problem with prevalence ranges of 4-46%, with 1-10% severely malnourished.
  91. ncbi Malnutrition was associated with poor quality of life in colorectal cancer: a retrospective analysis
    Digant Gupta
    Cancer Treatment Centers of America at Midwestern Regional Medical Center, Operations Center, Office of Research, 2610 Sheridan Road, Zion, IL 60099, USA
    J Clin Epidemiol 59:704-9. 2006
    b>Malnutrition is a significant cause of morbidity and mortality in advanced colorectal cancer, and little is known about its relationship with quality of life (QoL)...
  92. ncbi Rheumatoid cachexia, central obesity and malnutrition in patients with low-active rheumatoid arthritis: feasibility of anthropometry, Mini Nutritional Assessment and body composition techniques
    Ann Charlotte Elkan
    Department of Rheumatology, R92, Karolinska Institute, Karolinska University Hospital Huddinge, 141 86, Stockholm, Sweden
    Eur J Nutr 48:315-22. 2009
    ..The objectives of this study were to evaluate body composition and nutritional status in patients with RA and the feasibility of bioelectrical impedance (BIA) to detect rheumatoid cachexia...
  93. ncbi The Reactive Scope Model - a new model integrating homeostasis, allostasis, and stress
    L Michael Romero
    Department of Biology, Tufts University, Medford, MA 02155, USA
    Horm Behav 55:375-89. 2009
    ..Reactive Scope Model and contrast it with the traditional model and with allostasis in the context of chronic malnutrition, changes in social status, and changes in stress responses due to early life experiences...
  94. doi Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence
    Geert Tom Heikens
    Department of Paediatrics, College of Medicine, University of Malawi, Blantyre, Malawi
    Lancet 371:1305-7. 2008
  95. ncbi Prognostic significance of Subjective Global Assessment (SGA) in advanced colorectal cancer
    D Gupta
    Cancer Treatment Centers of America at Midwestern Regional Medical Center, Zion, IL 60099, USA
    Eur J Clin Nutr 59:35-40. 2005
    ..To evaluate the prognostic significance of Subjective Global Assessment (SGA) in advanced colorectal cancer and create statistically distinct prognostic groups of colorectal cancer patients based on clinical and nutritional variables...
  96. pmc Prevalence and risk factors for transmission of infection among children in household contact with adults having pulmonary tuberculosis
    M Singh
    Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Arch Dis Child 90:624-8. 2005
    ..To study the prevalence of tuberculosis infection among children in household contact with adults having pulmonary tuberculosis, and identify the possible risk factors...
  97. pmc Nutritional deficiencies in obesity and after bariatric surgery
    Stavra A Xanthakos
    Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2010, Cincinnati, OH 45229, USA
    Pediatr Clin North Am 56:1105-21. 2009
    ..This article reviews current knowledge of nutritional deficits in obese and overweight individuals and those that commonly present after bariatric surgery and summarizes current recommendations for screening and supplementation...
  98. ncbi Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: a 5-year prospective study
    Ibrahim Akdag
    Department of Nephrology and Rheumatology, Uludag University Medical School, Bursa, Turkey
    Nephron Clin Pract 108:c99-c105. 2008
    ..In this study we sought to investigate the clinical value of the malnutrition-inflammation-atherosclerosis (MIA) syndrome for long-term prediction of cardiovascular mortality in patients ..
  99. pmc Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice
    Josep C Jimenez-Chillaron
    Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 58:460-8. 2009
    ..We aimed to determine whether such metabolic phenotypes can be transmitted to subsequent generations in an experimental model, even in the absence of altered nutrition during the second pregnancy...
  100. ncbi EuroOOPS: an international, multicentre study to implement nutritional risk screening and evaluate clinical outcome
    Janice Sorensen
    Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, 30 Rolighedsvej, 1958 Frederiksberg C, Denmark
    Clin Nutr 27:340-9. 2008
    ..The aim of the study was to implement nutritional risk screening (NRS-2002) and to assess the association between nutritional risk and clinical outcome...
  101. ncbi Short stature of mothers from an area endemic for undernutrition is associated with obesity, hypertension and stunted children: a population-based study in the semi-arid region of Alagoas, Northeast Brazil
    Haroldo S Ferreira
    Faculdade de Nutrição, Universidade Federal de Alagoas, Campus A C Simões, Campus Universitario, 57072 970 Maceió, AL, Brazil
    Br J Nutr 101:1239-45. 2009
    ..019) in the offspring. Thus, in the semi-arid region of Alagoas, women of short stature presented a higher prevalence of chronic degenerative diseases and produced less healthy children than women of normal stature...

Research Grants74

  1. Hybrid Optical/Doppler Imaging of Ischemia in NEC - a multicenter trial
    David A Benaron; Fiscal Year: 2010
    ..Finally, Neonates recovering from NEC often incur additional serious complications (malnutrition, liver dysfunction)...
  2. Vitamin A adjuvant to enhance gut immunity and rotavirus vaccines in neonates
    Linda J Saif; Fiscal Year: 2010
    ..In developing countries, widespread malnutrition with micronutrient deficiencies (vitamin A, etc) and multiple concurrent infections compromise children's ..
  3. Maternal nutrient restriction and nonhuman primate fetal skeletal muscle developm
    Min Du; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Fetal nutrient deficiency results from many conditions in pregnancy, e.g. maternal malnutrition, reduced placenta efficiency, adolescence pregnancy, and closely spaced pregnancy...
  4. New drug VS-110 for treating inflammatory bowel diseases
    Jinshyun Ruth Wu-Wong; Fiscal Year: 2013
    ..Symptoms may include abdominal pain, severe diarrhea and malnutrition. IBD primarily includes ulcerative colitis (UC) and Crohn's disease (CD)...
    ..It is probable that the high prevalence of malnutrition in the region, worsened by HIV disease, is a factor in both early mortality and overall ART outcomes...
  6. Nutrition and Anabolic Interventions in Cancer Cachexia
    Melinda Sheffield-Moore; Fiscal Year: 2013
    ..In the clinical realm, malnutrition and cachexia are synonymous...
  7. Mechanisms of ethanol-induced neurodevelopmental effects
    Marina Guizzetti; Fiscal Year: 2011
    ..It may also help understanding why in some very poor regions of South Africa the prevalence of FAS is much higher than in Western countries as these populations also experience severe malnutrition.
    CLAIRE L MURPHY; Fiscal Year: 2013
    ..1990). Chemosensory, behavioral, and metabolic abnormalities lead to malnutrition and weight loss, furthering morbidity in this precarious disease population (Guirin et al, 2005;reviewed in ..
  9. Leptin as a Regulator of T Cell Metabolism and Function
    NANCIE MACIVER; Fiscal Year: 2013
    ..Deficits in adipose tissue, as seen in malnutrition, lead to a deficiency of the adipose hormone leptin, which plays a critical role in metabolic regulation as ..
  10. Effect Ultraviolet Radiation on Latent M. tuberculosis Infection in Guinea Pigs
    Amminikutty Jeevan; Fiscal Year: 2010
    ..may develop years later in some individuals as their immune system is compromised by HIV infection, malnutrition or the use of immunosuppressive agents...
    SHELLY CHI LOO LU; Fiscal Year: 2013
  12. Biliary Atresia, Cholestatic Liver Diseases, and Cystic Fibrosis: Indiana Univers
    Jean Pappas Molleston; Fiscal Year: 2013
    ..Relevance: Pediatric liver disease, associated with chronic illness, malnutrition, and the need for liver transplantation, has significant public health impact...
  13. Developmental Origins of Phenotypic Characteristics that Predict Longevity
    Andrzej Bartke; Fiscal Year: 2012
  14. The human gut microbiome, malnutrition and vaccine responses
    ANDREW LEON KAU; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Malnutrition kills millions of children worldwide every year. Much of their morbidity and mortality is a result of infections, including those caused by enteropathogens...
  15. Epigenomic Regulation of Gene Expression in Diet Induced Obesity
    Donald K Scott; Fiscal Year: 2012
    ..are perhaps best exemplified by recent studies demonstrating that the intrauterine environment, either malnutrition or overnutrition, influences gene expression through differential methylation of genes that lead to an altered ..
  16. Skeletal Muscle Mitochondrial Adaptations to a Two-Year Caloric Restiction
    STEVEN RICHARD SMITH; Fiscal Year: 2012
    ..Calorie restriction (CR), without malnutrition, is a well-known dietary intervention that consistently increases life span by delaying the aging process in a ..
  17. NKT cells, fatty acids, and insulin resistance
    CURTIS LEE GABRIEL; Fiscal Year: 2010
    ..status and immune system function become apparent when one examines the diametrically opposite epidemics of malnutrition and overnutrition...
  18. Monoamine Contributions to Neurocircuitry in Eating Disorders
    Walter H Kaye; Fiscal Year: 2013
    ..In order to avoid the confounding effects of malnutrition, and because they have behaviors and neural circuit alterations relevant for this study, we will study 25 ..
  19. Assessment of Dehydration in Children with Diarrhea in Resource-Limited Settings
    ADAM CARL LEVINE; Fiscal Year: 2013
    ..clinical trial design and management, cost- effectiveness analysis, the pathophysiology of diarrhea and malnutrition, and the ethics of conducting research in resource-limited settings, which will be completed during the five ..
  20. The Role of Syntrophic Bacteria in Methanogenic Metabolism in the Human Gut
    Catherine Lozupone; Fiscal Year: 2013
    ..research on the association of the gut microbial community with diseases of nutrition (obesity and malnutrition) and the application of gnotobiotic mouse models to understanding microbial interactions in the gut...
  21. Mechanisms of ER stress - induced fatty liver
    D Thomas Rutkowski; Fiscal Year: 2013
    ..liver disease (FLD) has a variety of causes including chronic alcohol consumption, obesity, viral infection, malnutrition, and acute exposure to hepatotoxins...
  22. Hospital and Household Studies of Respiratory Cryptosporidiosis and Transmission
    Jeffrey K Griffiths; Fiscal Year: 2013
    ..may limit RT infection, in contrast to malnutrition or HIV which may facilitate or worsen clinical RT infection...
  23. Alterations in membrane composition and function eith calorie restriction
    Jon J Ramsey; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): Calorie restriction (CR), without malnutrition, is the only intervention that has consistently been shown to increase maximum life span and prevent or delay the onset of age-associated ..
  24. Causes of rotavirus vaccine failure in Zambian children
    Roma Chilengi; Fiscal Year: 2013
    ..ii) Malnutrition negatively impacts infant immunity and increases the risk of post-vaccination rotavirus gastroenteritis...
  25. Gut microflora: Impact on neonatal immunity, viral gastroenteritis and vaccines
    ..b>Malnutrition (kwashiorkor) and frequent antibiotic usage in infants affect the gut microbiome and barrier integrity, likely ..
  26. Effect of a sanitation &nutrition intervention on HIV-exposed infant health
    JEAN HAWES HUMPHREY; Fiscal Year: 2012
    ..5 to -2.5, followed by little or no recovery thereafter. The resulting underweight and stunting malnutrition underlies 50% and 35%, respectively, of all under-5 mortality, and results in long-term deficits in cognitive ..
  27. Mechanisms of Interleukin-17 Inflammation Induced by Bacteroides fragilis
    CYNTHIA SEARS; Fiscal Year: 2012
    ..The first is infectious diarrheal diseases, a global cause of morbidity and mortality that is associated with malnutrition and delayed cognitive development in children;and the second is colorectal cancer, the second leading cause of ..
  28. Gene Networks Regulating Muscle Protein Degradation
    Nathaniel J Szewczyk; Fiscal Year: 2010
    ..provided by applicant): Muscle atrophy is associated with increased mortality in patients with chronic malnutrition, denervation, sepsis, cancer, diabetes, renal failure, heart failure, AIDS and in aging patients...
  29. IRS insecticides for malaria control and child neurodevelopment in South Africa
    Brenda Eskenazi; Fiscal Year: 2013
    ..the relative and synergistic health impacts of alternative IRS insecticides;and 4) evaluate whether poverty, malnutrition and poor health potentiate the health effects of these exposures...
  30. Targeting Bacterial Virulence Transcription Factors, a Novel Antibiotic Approach
    George A Garcia; Fiscal Year: 2011
    ..Persistent cases of diarrhea cause malnutrition, retard growth, and delay mental development...
  31. Maternal nutrient restriction: Effects on offspring immune function
    Mark J Nijland; Fiscal Year: 2013
    ..B cells will provide the first insights into specific mechanisms that effect long-term immune consequences of malnutrition during pregnancy...
  32. Changes in antioxidants and susceptibility to parasites
    DEBORAH KRISTAN; Fiscal Year: 2012
    ..Chronic calorie restriction (CR) is prolonged low calorie intake without malnutrition. CR has many physiological benefits, including enhanced immune function as tested with antigens and mitogens...
  33. Investigation of synergy between Rifampin and SQ109, a new anti-TB drug candidate
    VENKATA REDDY; Fiscal Year: 2009
    ..individuals becomes even less in the setting of secondary immunosuppression caused by HIV and malnutrition, conditions that are rampant in developing countries...
  34. Mechanisms of host-bacterial interactions, ileitis and granuloma formation in Agr
    Steven M Lipkin; Fiscal Year: 2013 chronic, relapsing intestinal inflammation producing debilitating symptoms of diarrhea, abdominal pain and malnutrition. Its main forms are Crohn's disease and ulcerative colitis...
  35. Fostering Opportunities for Nutrition and Global Health
    Wafaie W Fawzi; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Malnutrition is the leading cause of death and disability worldwide, and is a major impediment to population health and economic development...
  36. Susceptibility and Protective Immunity to Noroviruses
    Ralph S Baric; Fiscal Year: 2013
    ..In developing nations, repeat infection likely contribute to malnutrition in infants and young children and may result in death...
  37. Hypothalamic Mechanisms in Cachexia
    Daniel L Marks; Fiscal Year: 2013
    ..This devastating state of malnutrition is brought about by a synergistic combination of a dramatic decrease in appetite and an increase in metabolism ..
  38. Omega-3 Fatty Acid Administration In Dialysis Patients
    Talat Alp Ikizler; Fiscal Year: 2010
    ..mediators of inflammatory response leading to muscle wasting lead to a unique form of protein and energy malnutrition, which can be termed "uremic wasting"...
  39. Antimicrobial and Regenerative Treatment for Oral Mucositis
    SHENDA BAKER; Fiscal Year: 2012
    ..including pain, oral lesions, dehydration and nutritional compromise including limiting calorie intake and malnutrition as well as the high risk for systemic infection...
  40. Protein intake, nutrition and cardiovascular disease in stage V CKD
    Srinivasan Beddhu; Fiscal Year: 2011
    ..The effects of protein intake on cardiovascular disease are also controversial. Malnutrition has been considered to be a uremic CV risk factor...
    Sherin U Devaskar; Fiscal Year: 2010
    ..Ten-twenty% of this epidemic arises because of in-utero/postnatal malnutrition with subsequent superimposition of western diet and sedentary life style...
  42. Giardia drug targets: Structure, function and inhibitors
    Osnat Herzberg; Fiscal Year: 2010
    ..Chronic infection leads to malnutrition, growth retardation in children, and death...
  43. Brain Reward Circuits and Computational Modeling in Adolescent Anorexia Nervosa
    GUIDO KW FRANK; Fiscal Year: 2013
    ..application we will study in adolescents with AN brain reward pathways, and how those circuits are affected by malnutrition and re-feeding, as well as stress hormones that are frequently altered in AN...
  44. Benefits of dietary essential amino acid restriction
    James Mitchell; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Dietary restriction (DR), or reduced food intake without malnutrition, is highly beneficial in a variety of experimental organisms using a number of endpoints, including glucose homeostasis, acute ..
  45. Waterless hand sanitizer for diarrhea prevention in a humanitarian emergency
    Pavani Kalluri Ram; Fiscal Year: 2013
    ..Intense crowding and acute and chronic malnutrition contribute to the high burden of diarrhea and acute respiratory infection...
  46. Taste and Cyclophosphamide in Mice
    Eugene R Delay; Fiscal Year: 2013
    ..Taste loss caused by chemotherapy frequently reduces food intake and results in malnutrition, lower quality of life, poorer recovery, and increased mortality...
  47. Remote food photography for the real-time measurement of children's food intake
    Corby K Martin; Fiscal Year: 2013
    ..Additionally, this method can be applied to clinical settings and provide a valuable tool for clinicians and patients to measure energy and nutrient intake. ..
  48. Effect of FADS gene variants on fatty acid synthesis &brain development in India
    AVINASH KUNJAN SHETTY; Fiscal Year: 2013
    ..Pregnant mothers and their developing fetuses as well as young children who are impacted by malnutrition are particularly vulnerable because the staple foods they ingest have little or no preformed DHA or AA...
  49. Muscle protein synthesis and gene expression in myostatin-deficient mice
    Stephen L Welle; Fiscal Year: 2010
    ..conditions, including muscular dystrophies, cancer, glucocorticoid administration, inactivity, arthritis, malnutrition, AIDS, and old age...
  50. Human Umami Taste: Genetics of Psychophysical Traits
    Paul A S Breslin; Fiscal Year: 2012
    ..Since children with protein malnutrition prefer foods that have added free amino acids in experimental settings, a better understanding of amino acid ..
  51. Genetic and Inflammatory Factors in Anemia in the Elderly
    Nancy Berliner; Fiscal Year: 2010
    ..2. To characterize the role of a chronic proinflammatory state in the age-stratified incidence of anemia. 3. To characterize the role of genetic polymorphisms in predicting the development of a proinflammatory state. ..
  52. Combinational Approaches to the Chemoprevention of Esophageal Cancer
    Tong Chen; Fiscal Year: 2012
    ..abstract_text> ..
  53. Impact of Malnutrition on HIV Treatment Failure in Resource-Limited Settings
    Amita Gupta; Fiscal Year: 2012
    ..mass index, and anemia, but these markers are nonspecific and could reflect advanced HIV, co-infections, and/or malnutrition. The relative contribution of malnutrition to early treatment failure in RLS is unknown...
  54. Effect of Nutrition, Immunity, and Vaccines on Pediatric Enteric Infections
    Juan S Leon; Fiscal Year: 2013
    ..3) To quantify the influence of severe malnutrition and immune-competence on RV infection and diarrhea after RV vaccination. TRAINING: Dr...
  55. Undernutrition in Pregnancy and Developmental Programming of Vascular Function
    Chengwen Sun; Fiscal Year: 2010
  56. Cost-effective chronic disease prevention in developing countries
    DESCRIPTION (provided by applicant): Despite the perception that infectious diseases and malnutrition are the main threats to health in the developing world, the reality is that the prevalence of chronic diseases is increasing rapidly...
  57. Molecular characterization of a hookworm Macrophage Migration Inhibitory Factor
    Jon J Vermeire; Fiscal Year: 2010
    Hookworm infection is the leading cause of malnutrition and anemia in the developing world...
  58. Malnutrition, Diet and Racial Disparities in CKD
    Kamyar Kalantar-Zadeh; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The purpose of this Mid-Career Investigator Award in "Malnutrition, Diet and Racial Disparities in CKD" by Kamyar Kalantar-Zadeh, MD, MPH, PhD, Associate Professor-in-Residence of Medicine, Pediatrics ..
  59. Significance of Pituitary Leptin to Gonadotropes
    Gwen V Childs; Fiscal Year: 2010
    ..aim of the study will be to determine how leptin supports reproductive competence and how information about malnutrition may be linked with infertility...
  60. Protection against renal ischemic injury by short term dietary restriction
    James Mitchell; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Dietary restriction (DR) is defined as reduced food consumption without malnutrition and extends lifespan in organisms as diverse as yeast, roundworms, fruit flies and mammals...
  61. Newborn Screening, Malnutrition and Lung Disease in Children with Cystic Fibrosis
    HuiChuan J Lai; Fiscal Year: 2013
    ..CF is characterized by gastrointestinal and pulmonary manifestations. Malnutrition and growth faltering are prevalent, and occur even in infants diagnosed through newborn screening (NBS)...
  62. Development of swallow evoked potentials as a novel tool to investigate swallowin
    Teresa E Lever; Fiscal Year: 2012
    ..Common symptoms include malnutrition, dehydration, and respiratory complications, all of which may result in a poor quality of life and contribute ..
    Ericka Hayes; Fiscal Year: 2009
    The objective of this project is to understand how severe malnutrition affects the pharmacokinetics of highly active antiretroviral therapy (HAART) as well as antioxidant capacity and mitochondrial integrity in HIV infected children ..
    Milton Saier; Fiscal Year: 2000
    ..They are primary causes of infant mortality, malnutrition and retarded mental and physical development worldwide...
    Michael Lewis; Fiscal Year: 1992
    ..In malnutrition, oxidative capacity of skeletal muscle fibers has been shown to be decreased, while in emphysema it has been ..
  66. Puberty, Immunity and Malnutrition in S. Japonicum
    Jonathan Kurtis; Fiscal Year: 2005
    ..the development of protective immune responses to schistosome infections Schistosomiasis is causally linked to malnutrition leading to the hypothesis that chronic infection results in attenuate growth for age and possibly delayed ..
    RHONDA KINEMAN; Fiscal Year: 2006
    ..alteration in GH production which contribute to the pathophysiology of clinically relevant disorders such as malnutrition, anorexia nervosa, obesity and diabetes...
  68. Oral Health Outcomes of Early Childhood Malnutrition
    Walter Psoter; Fiscal Year: 2006
    ..The primary objectives of this retrospective cohort study are to assess the impact of early protein-energy malnutrition (PEM) on the permanent dentition, specifically with respect to: 1) dental caries, 2) enamel hypoplasia, 3) ..
  69. Slowing of Transit - The Third Enteric Function of 5-HT
    Henry Lin; Fiscal Year: 2005
    ..Abdominal pain, nausea, bloating, diarrhea and malnutrition are the consequences of impaired control of intestinal transit...
  70. Molecular tools to monitor eradication of Schistosoma haematobium transmission
    Charles King; Fiscal Year: 2009
    ..This tool will provide a highly useful method of directing schistosomiasis control programs, and could lead to much more effective targeted strategies for eradication of parasite transmission. ..
  71. Oxidative Stress in Alcoholic Cardiomyopathy
    Charles Lui; Fiscal Year: 2004
    ..Since selenium and vitamin deficiencies are common among alcoholics, possibly as a result of malnutrition and/or malabsorption, it is hypothesized that alcoholic cardiomyopathy is caused by long-term alcohol abuse in ..
  72. Acu/Moxa for Peripheral Neuropathy in Pts with HIV
    JOYCE ANASTASI; Fiscal Year: 2007
    ..The effects of symptom reduction on quality of life will also be examined. In addition, this application originates from an institution with a NIH Center for AIDS Research (CFAR) and a supportive community network. ..
  73. Feasibility Study of Probiotics for Growth Faltering
    Christine Wanke; Fiscal Year: 2006
    Diarrheal disease and growth faltering that occur at the time of weaning are significant public health problems. Malnutrition is associated with more than half of the 10 million deaths per year in children under the age of five in the ..
  74. Testosterone:Physical Function in Men on Hemodialysis
    Shalender Bhasin; Fiscal Year: 2004
    b>Malnutrition and loss of muscle mass (sarcopenia) are common in patients with end stage renal disease on hemodialysis and associated with increased mortality, impaired physical function, disability, and poor quality of life...